Bioconductor Affymetrix Probe Listing

Probe	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	PubMed	Gene Ontology	Pathway
TC1100003401.mm.2	Ccl3	chemokine (C-C motif) ligand 3	11	-83647842	NM_011337, BC111443 NM_011337, BC111443	20302	260	monocyte chemotaxis cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity chemokine activity regulation of cell shape neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production positive regulation of neuron apoptotic process positive regulation of GTPase activity astrocyte cell migration positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II CCR chemokine receptor binding macrophage chemotaxis lymphocyte chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor	04060 04062 04620 05142 05323
TC1200000203.mm.2	Rrm2	ribonucleotide reductase M2	12	24708253	NM_009104, BC085136 NM_009104, BC085136	20135	72	blastocyst development ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding nuclear envelope cytoplasm cytosol cytosol cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication ferric iron binding deoxyribonucleotide metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity identical protein binding protein homodimerization activity metal ion binding protein heterotetramerization	00230 00240 00480 01100 04115
TC0600001606.mm.2	Emp1	epithelial membrane protein 1	6	135362930, 135367492	NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491	13730	29	plasma membrane plasma membrane cell death membrane integral component of membrane cell growth bleb assembly
TC0800001737.mm.2	Gas6	growth arrest specific 6	8	-13465373	NM_019521, BC005444 NM_019521, BC005444	14456	109	neuron migration phosphatidylserine binding positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of glomerular filtration signaling receptor binding calcium ion binding extracellular region extracellular space extracellular space extracellular space cytoplasm protein phosphorylation phagocytosis signal transduction enzyme linked receptor protein signaling pathway blood coagulation cellular response to starvation positive regulation of gene expression negative regulation of tumor necrosis factor-mediated signaling pathway macrophage cytokine production peptidyl-serine phosphorylation fusion of virus membrane with host plasma membrane viral genome replication protein tyrosine kinase activator activity protein-macromolecule adaptor activity receptor tyrosine kinase binding cell-substrate adhesion positive regulation of TOR signaling activation of protein kinase B activity negative regulation of interferon-gamma production negative regulation of interleukin-1 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of natural killer cell differentiation positive regulation of peptidyl-serine phosphorylation cellular response to interferon-alpha cellular response to drug B cell chemotaxis regulation of growth cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic cell clearance apoptotic cell clearance negative regulation of DNA-binding transcription factor activity protein kinase B signaling protein kinase B signaling protein kinase B signaling protein kinase B signaling positive regulation of protein kinase activity negative regulation of transcription, DNA-templated viral entry into host cell receptor-mediated virion attachment to host cell positive regulation of protein export from nucleus metal ion binding receptor ligand activity receptor ligand activity receptor ligand activity positive regulation of fibroblast proliferation positive regulation of phagocytosis positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport cellular response to vitamin K cellular response to glucose stimulus cellular response to growth factor stimulus cellular response to growth factor stimulus protein localization to plasma membrane hematopoietic stem cell migration to bone marrow negative regulation of oligodendrocyte apoptotic process negative regulation of fibroblast apoptotic process negative regulation of endothelial cell apoptotic process positive regulation of dendritic cell chemotaxis negative regulation of dendritic cell apoptotic process
TC0400001856.mm.2	Dhrs3	dehydrogenase/reductase (SDR family) member 3	4	144893136, 144892826, 144893076	NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540	20148	30	retinoid metabolic process retinoid metabolic process outflow tract morphogenesis retinol dehydrogenase activity retinol dehydrogenase activity lipid droplet membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor regulation of ossification retinol metabolic process regulation of retinoic acid receptor signaling pathway negative regulation of retinoic acid receptor signaling pathway NADP-retinol dehydrogenase activity roof of mouth development bone morphogenesis cardiac septum morphogenesis	00830 01100
TC1000000372.mm.2	Sesn1	sestrin 1	10	41810573, 41887438	NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403	140742	33	fibrillar center protein binding nucleus nucleoplasm cytoplasm cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor negative regulation of cell growth TORC2 complex cellular response to amino acid starvation cellular response to glucose starvation regulation of protein kinase B signaling GATOR2 complex GATOR2 complex leucine binding leucine binding cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process cellular oxidant detoxification regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation	04115
TC0100000298.mm.2	Il1rl1	interleukin 1 receptor-like 1	1	40439628, 40439628, 40429569	NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445	17082	293	interleukin-33 binding interleukin-33 binding interleukin-33 receptor activity interleukin-33 receptor activity negative regulation of T-helper 1 type immune response interleukin-1 receptor activity protein binding extracellular region extracellular space cytosol plasma membrane focal adhesion signal transduction negative regulation of cell population proliferation external side of plasma membrane external side of plasma membrane cell surface membrane integral component of membrane hydrolase activity extracellular matrix negative regulation of interferon-gamma production positive regulation of chemokine production positive regulation of interleukin-5 production positive regulation of macrophage activation negative regulation of I-kappaB kinase/NF-kappaB signaling NAD(P)+ nucleosidase activity positive regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating
TC0400001639.mm.2	Stmn1	stathmin 1	4	134468319	NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396	16765	112	mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm cytoplasm cytosol cytoskeleton microtubule microtubule depolymerization microtubule depolymerization mitotic spindle organization multicellular organism development nervous system development axonogenesis tubulin binding tubulin binding membrane cell differentiation regulation of microtubule polymerization or depolymerization regulation of microtubule polymerization or depolymerization negative regulation of microtubule polymerization negative regulation of microtubule polymerization neuron projection development negative regulation of Rho protein signal transduction neuron projection hepatocyte growth factor receptor signaling pathway positive regulation of cellular component movement negative regulation of stress fiber assembly establishment of skin barrier negative regulation of thrombin-activated receptor signaling pathway negative regulation of guanyl-nucleotide exchange factor activity	04010
TC0500003472.mm.2					NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024			nucleotide binding double-strand break repair via break-induced replication in utero embryonic development negative regulation of B cell apoptotic process DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytosol DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cellular response to DNA damage stimulus cell cycle cell aging sensory perception of sound cell population proliferation Wnt signaling pathway hydrolase activity regulation of phosphorylation MCM complex MCM complex negative regulation of apoptotic process regulation of viral genome replication regulation of viral genome replication long-term synaptic potentiation SMAD protein signal transduction cellular response to inorganic substance cellular response to xenobiotic stimulus cellular response to forskolin single-stranded 3'-5' DNA helicase activity
TC0400001934.mm.2	Srm	spermidine synthase	4	148591512	NM_009272, BC005566 NM_009272, BC005566	20810	24	catalytic activity spermidine synthase activity spermidine synthase activity polyamine metabolic process polyamine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process transferase activity identical protein binding protein homodimerization activity cellular response to leukemia inhibitory factor	00270 00330 00410 00480 01100
TC1400000176.mm.2	Plau	plasminogen activator, urokinase	14	20836661	NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713	18792	311	angiogenesis response to hypoxia serine-type endopeptidase activity protein binding extracellular region extracellular space extracellular space proteolysis peptidase activity serine-type peptidase activity positive regulation of cell population proliferation cell surface regulation of signaling receptor activity smooth muscle cell migration regulation of smooth muscle cell migration positive regulation of smooth muscle cell migration membrane hydrolase activity positive regulation of cell migration plasminogen activation plasminogen activation regulation of cell adhesion mediated by integrin regulation of cell adhesion mediated by integrin wound healing regulation of cell population proliferation fibrinolysis fibrinolysis skeletal muscle tissue regeneration positive regulation of ovulation neuron death regulation of smooth muscle cell-matrix adhesion regulation of hepatocyte proliferation positive regulation of reactive oxygen species metabolic process	04610
TC1400002746.mm.2	Gpr183	G protein-coupled receptor 183	14	-121952330	NM_183031, BC052868 NM_183031, BC052868	321019	50	adaptive immune response B cell activation involved in immune response mature B cell differentiation involved in immune response immune system process dendritic cell chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane humoral immune response signal transduction G protein-coupled receptor signaling pathway oxysterol binding oxysterol binding T cell chemotaxis membrane integral component of membrane osteoclast differentiation leukocyte chemotaxis leukocyte chemotaxis positive regulation of B cell proliferation positive regulation of B cell proliferation dendritic cell homeostasis cell chemotaxis T follicular helper cell differentiation positive regulation of ERK1 and ERK2 cascade regulation of astrocyte chemotaxis
TSUnmapped00000029.mm.2	Psd3	pleckstrin and Sec7 domain containing 3	8	-67689081, -67689081, -67689081	NM_177698	234353	22	guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse	04144
TC0600002233.mm.2	Tmem176b	transmembrane protein 176B	6	-48833810, -48833811, -48833811	NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166	65963	34	protein binding nucleus membrane integral component of membrane cell differentiation negative regulation of dendritic cell differentiation negative regulation of dendritic cell differentiation
TC1100001220.mm.2	Ccl7	chemokine (C-C motif) ligand 7	11	82045711	NM_013654, BC061126 NM_013654, BC061126	20306	80	monocyte chemotaxis cytokine activity extracellular region extracellular space extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity heparin binding neutrophil chemotaxis CCR2 chemokine receptor binding positive regulation of GTPase activity CCR chemokine receptor binding eosinophil chemotaxis lymphocyte chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to ethanol	04060 04062
TC0900001182.mm.2	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9	9	94669891	NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825	331004	22	endosome plasma membrane ion transport cation transport sodium ion transport regulation of pH antiporter activity solute:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity membrane integral component of membrane regulation of intracellular pH recycling endosome recycling endosome transmembrane transport potassium ion transmembrane transport sodium ion import across plasma membrane
TC1100000168.mm.2	Cnrip1	cannabinoid receptor interacting protein 1	11	17051858	NM_029861, BC087946 NM_029861, BC087946	380686	27	cytoplasm plasma membrane plasma membrane protein C-terminus binding regulation of signaling receptor activity type 1 cannabinoid receptor binding type 1 cannabinoid receptor binding myelin sheath negative regulation of signaling receptor activity negative regulation of signaling receptor activity
TC0200002532.mm.2	Ube2c	ubiquitin-conjugating enzyme E2C	2	164769928	NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033	68612	25	ubiquitin ligase complex nucleotide binding protein polyubiquitination ubiquitin-protein transferase activity ATP binding nucleus anaphase-promoting complex cytosol plasma membrane ubiquitin-dependent protein catabolic process cell cycle exit from mitosis free ubiquitin chain polymerization protein ubiquitination transferase activity regulation of mitotic metaphase/anaphase transition anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of exit from mitosis ubiquitin-like protein ligase binding cell division ubiquitin conjugating enzyme activity ubiquitin conjugating enzyme activity protein K48-linked ubiquitination protein K11-linked ubiquitination	04120
TC0200001045.mm.2	Itga6	integrin alpha 6	2	71786938	NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095	16403	274	integrin binding protein binding basement membrane plasma membrane plasma membrane adherens junction cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex external side of plasma membrane basal plasma membrane cell surface cell surface positive regulation of cell-substrate adhesion positive regulation of neuron projection development membrane integral component of membrane basolateral plasma membrane positive regulation of cell-cell adhesion hemidesmosome filopodium positive regulation of cell migration cell-substrate adhesion cellular response to extracellular stimulus insulin-like growth factor I binding cell adhesion mediated by integrin integrin alpha6-beta4 complex nail development neuregulin binding positive regulation of phosphorylation odontogenesis of dentin-containing tooth positive regulation of apoptotic process laminin binding positive regulation of GTPase activity skin morphogenesis protein-containing complex binding basal part of cell positive regulation of transcription by RNA polymerase II filopodium assembly metal ion binding brown fat cell differentiation leukocyte migration leukocyte migration cell-cell adhesion negative regulation of extrinsic apoptotic signaling pathway	04510 04512 04514 04640 04810 05145 05200 05222 05410 05412 05414
TC1900000216.mm.2					XM_986941
TC0300001639.mm.2	Fabp4	fatty acid binding protein 4, adipocyte	3	-10204342	NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426	11770	198	cytokine production long-chain fatty acid transporter activity fatty acid binding nucleus nucleoplasm cytoplasm cytosol negative regulation of protein kinase activity fatty acid metabolic process positive regulation of cell population proliferation lipid binding response to bacterium long-chain fatty acid transport long-chain fatty acid binding cholesterol homeostasis negative regulation of transcription, DNA-templated regulation of inflammatory response positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation hormone receptor binding cellular response to lithium ion cellular response to tumor necrosis factor positive regulation of cold-induced thermogenesis	03320
TC1500000031.mm.2	Dab2	disabled 2, mitogen-responsive phosphoprotein	15	6386747, 6299788	NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887	13132	118	negative regulation of transcription by RNA polymerase II cell morphogenesis involved in differentiation fibrillar center in utero embryonic development positive regulation of receptor recycling positive regulation of protein phosphorylation positive regulation of receptor internalization integrin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis pinocytosis apoptotic process activation of JUN kinase activity multicellular organism development endoderm development excretion protein C-terminus binding positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation negative regulation of neuron projection development protein transport membrane Wnt signaling pathway apical plasma membrane myeloid cell differentiation clathrin coat of coated pit clathrin-coated vesicle cell differentiation clathrin binding negative regulation of cell growth positive regulation of cell migration positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway clathrin-coated vesicle membrane cytoplasmic vesicle negative regulation of protein binding positive regulation of aldosterone biosynthetic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of transcription elongation from RNA polymerase II promoter leading edge cell differentiation phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity clathrin adaptor activity cargo receptor activity cargo receptor activity negative regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle positive regulation of cell adhesion positive regulation of cell adhesion positive regulation of endocytosis positive regulation of endocytosis positive regulation of transcription by RNA polymerase II SMAD binding clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm response to steroid hormone negative regulation of epithelial cell proliferation low-density lipoprotein particle receptor binding positive regulation of SMAD protein signal transduction negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of protein localization to plasma membrane negative regulation of protein localization to plasma membrane positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of Rho-dependent protein serine/threonine kinase activity positive regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of early endosome to late endosome transport positive regulation of aldosterone secretion positive regulation of integrin-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway	04144
TC0100003026.mm.2	Mcm6	minichromosome maintenance complex component 6	1	-128331574	NM_008567, BC050886, BC057584 NM_008567, BC050886, BC057584 NM_008567, BC050886, BC057584	17219	58	nucleotide binding double-strand break repair via break-induced replication DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation cell cycle hydrolase activity MCM complex MCM complex identical protein binding mitotic DNA replication single-stranded 3'-5' DNA helicase activity	03030 04110
TC1000000937.mm.2	Chst11	carbohydrate sulfotransferase 11	10	82985496	NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793	58250	35	N-acetylgalactosamine 4-O-sulfotransferase activity in utero embryonic development chondrocyte development Golgi apparatus carbohydrate metabolic process respiratory gaseous exchange by respiratory system sulfotransferase activity sulfotransferase activity post-embryonic development membrane integral component of membrane carbohydrate biosynthetic process transferase activity proteoglycan biosynthetic process chondroitin sulfate metabolic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process embryonic limb morphogenesis negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization post-anal tail morphogenesis regulation of cell population proliferation embryonic digit morphogenesis negative regulation of apoptotic process chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity cartilage development	00532 00920
TC1500000453.mm.2	Myc	myelocytomatosis oncogene	15	61985340	NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932	17869	1226	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade re-entry into mitotic cell cycle chromatin euchromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding core promoter sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in ureteric bud morphogenesis B cell apoptotic process positive regulation of mesenchymal cell proliferation regulation of oxidative phosphorylation positive regulation of B cell apoptotic process DNA binding DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm spindle glucose metabolic process chromatin remodeling transcription, DNA-templated DNA-templated transcription, initiation regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II pyruvate transport amino acid transport cellular iron ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus inner mitochondrial membrane organization cell cycle arrest regulation of mitotic cell cycle transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage response to radiation response to radiation response to gamma radiation regulation of gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of mitochondrial membrane potential positive regulation of smooth muscle cell migration Wnt signaling pathway protein processing nuclear body transformation of host cell by virus axon ubiquitin protein ligase binding negative regulation of protein binding regulation of telomere maintenance protein-DNA complex disassembly protein-containing complex activating transcription factor binding cellular response to interferon-alpha cellular response to drug cellular response to drug skeletal muscle cell differentiation middle ear morphogenesis regulation of apoptotic process regulation of apoptotic process positive regulation of catalytic activity response to alkaloid positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of DNA binding pigmentation sequence-specific DNA binding canonical Wnt signaling pathway involved in negative regulation of apoptotic process canonical Wnt signaling pathway involved in positive regulation of apoptotic process protein-containing complex binding negative regulation of monocyte differentiation positive regulation of cell cycle positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of glucose import lactic acid secretion protein dimerization activity positive regulation of fibroblast proliferation negative regulation of fibroblast proliferation perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation skeletal system morphogenesis positive regulation of epithelial cell proliferation detection of mechanical stimulus involved in sensory perception of sound chromosome organization negative regulation of cell division positive regulation of telomerase activity positive regulation of glial cell proliferation positive regulation of transcription initiation from RNA polymerase II promoter negative regulation of cell death ERK1 and ERK2 cascade repressing transcription factor binding E-box binding cellular response to hypoxia positive regulation of metanephric cap mesenchymal cell proliferation positive regulation of cellular respiration positive regulation of oxidative phosphorylation regulation of somatic stem cell population maintenance positive regulation of DNA methylation positive regulation of DNA biosynthetic process positive regulation of response to DNA damage stimulus positive regulation of ATP biosynthetic process positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway	04010 04012 04110 04310 04350 04630 05200 05210 05213 05216 05219 05220 05221 05222
TC0500001734.mm.2	Daglb	diacylglycerol lipase, beta	5	143464492	NM_144915, BC016105 NM_144915, BC016105	231871	29	prostaglandin biosynthetic process triglyceride lipase activity nucleoplasm plasma membrane lipid metabolic process icosanoid metabolic process G protein-coupled glutamate receptor signaling pathway neuroblast proliferation positive regulation of triglyceride catabolic process membrane integral component of membrane lipid catabolic process lipase activity lipase activity hydrolase activity arachidonic acid metabolic process arachidonic acid metabolic process arachidonic acid metabolic process neurogenesis neurogenesis neurotransmitter biosynthetic process neurotransmitter biosynthetic process postsynaptic membrane metal ion binding regulation of inflammatory response endocannabinoid signaling pathway retrograde trans-synaptic signaling by endocannabinoid
TC0600002491.mm.2	Mat2a	methionine adenosyltransferase II, alpha	6	-72432795	NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360	232087	42	nucleotide binding methionine adenosyltransferase activity methionine adenosyltransferase activity methionine adenosyltransferase activity ATP binding cytosol cytosol S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to hormone amino acid binding transferase activity protein hexamerization response to drug identical protein binding metal ion binding methionine adenosyltransferase complex methionine adenosyltransferase complex protein heterooligomerization response to cAMP cellular response to leukemia inhibitory factor	00270 01100
TC1200001605.mm.2	Pik3cg	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	12	-32173396, -32173396	NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246	30955	302	nucleotide binding angiogenesis regulation of protein phosphorylation immune system process positive regulation of acute inflammatory response sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex, class IA phosphatidylinositol 3-kinase complex, class IB phosphatidylinositol 3-kinase complex, class IB protein phosphorylation endocytosis chemotaxis inflammatory response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of endothelial cell migration positive regulation of endothelial cell migration negative regulation of triglyceride catabolic process phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling membrane membrane kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity phosphorylation cell migration transferase activity secretory granule localization 1-phosphatidylinositol-4-phosphate 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity positive regulation of Rac protein signal transduction positive regulation of Rac protein signal transduction phosphatidylinositol-3-phosphate biosynthetic process identical protein binding positive regulation of catalytic activity positive regulation of MAP kinase activity phosphatidylinositol phosphorylation phosphatidylinositol phosphorylation ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-mediated signaling positive regulation of protein kinase B signaling phosphatidylinositol kinase activity cellular response to cAMP hepatocyte apoptotic process regulation of calcium ion transmembrane transport negative regulation of fibroblast apoptotic process	00562 04012 04062 04070 04150 04210 04370 04380 04510 04620 04630 04650 04660 04662 04664 04666 04670 04722 04810 04910 04914 04930 04960 04973 05100 05142 05145 05146 05160 05200 05210 05211 05212 05213 05214 05215 05218 05220 05221 05222 05223
TC0100000476.mm.2	Cd28	CD28 antigen	1	60746387	NM_007642, BC064058, CD28 NM_007642, BC064058, CD28 NM_007642, BC064058, CD28	12487	502	immunological synapse protease binding positive regulation of inflammatory response to antigenic stimulus plasma membrane immune response external side of plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression positive regulation of phosphatidylinositol 3-kinase signaling membrane integral component of membrane protein kinase binding T cell costimulation T cell costimulation T cell costimulation T cell costimulation T cell costimulation positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation T cell activation T cell activation regulation of T cell proliferation identical protein binding negative thymic T cell selection regulatory T cell differentiation membrane raft regulation of regulatory T cell differentiation positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation positive regulation of isotype switching to IgG isotypes T cell receptor signaling pathway T cell receptor signaling pathway positive regulation of protein kinase B signaling apoptotic signaling pathway protein complex involved in cell adhesion	04514 04660 04672 04940 05320 05322 05323 05330 05332 05416
TC0800002992.mm.2	Maf	avian musculoaponeurotic fibrosarcoma oncogene homolog	8	-115703252	NM_001025577	17132	182	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production lens development in camera-type eye DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II positive regulation of gene expression regulation of chondrocyte differentiation identical protein binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cell development inner ear development lens fiber cell differentiation lens fiber cell differentiation sequence-specific double-stranded DNA binding
TC0300000627.mm.2	Gask1b	golgi associated kinase 1B	3	79885929	NM_133187, BC056975 NM_133187, BC056975	68659	14	molecular_function Golgi apparatus biological_process membrane integral component of membrane
TC0600001433.mm.2	Cdca3	cell division cycle associated 3	6	124830175	NM_013538, BC002006 NM_013538, BC002006	14793	23	molecular_function cytoplasm adherens junction cell cycle cell division
TC1100004051.mm.2	Cd300lb	CD300 molecule like family member B	11	-114922778	NM_199221, CD300, BC160263 NM_199221, CD300, BC160263 NM_199221, CD300, BC160263	217304	21	immune system process neutrophil mediated immunity transmembrane signaling receptor activity protein binding plasma membrane membrane integral component of membrane positive regulation of mast cell activation cellular response to lipopolysaccharide
TC1100003561.mm.2	Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	11	-94343294	NM_029600, BC150788 NM_029600, BC150788	76408	46	nucleotide binding ATP binding plasma membrane integral component of plasma membrane drug transmembrane transport ABC-type xenobiotic transporter activity glucuronoside transmembrane transporter activity ABC-type glutathione S-conjugate transporter activity ABC-type bile acid transporter activity bile acid and bile salt transport canalicular bile acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane ATPase activity transmembrane transporter activity ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transport xenobiotic transmembrane transporter activity transmembrane transport transmembrane transport icosanoid transmembrane transporter activity leukotriene transport anion transmembrane transport	02010 04976
TC1400001676.mm.2	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	14	-31372613, -31372613	NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741	24056	27	protein kinase inhibitor activity protein kinase inhibitor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytoplasm mitochondrion negative regulation of protein kinase activity membrane nuclear body SH3 domain binding cytoplasmic vesicle membrane cytoplasmic vesicle intracellular signal transduction intracellular signal transduction negative regulation of protein tyrosine kinase activity
TC0600002404.mm.2	Hpgds	hematopoietic prostaglandin D synthase	6	-65117292	NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737	54486	47	magnesium ion binding prostaglandin biosynthetic process glutathione transferase activity glutathione transferase activity prostaglandin-D synthase activity prostaglandin-D synthase activity calcium ion binding nucleoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process prostaglandin metabolic process glutathione metabolic process transferase activity isomerase activity protein homodimerization activity intracellular membrane-bounded organelle negative regulation of male germ cell proliferation	00590 01100
TC0700004624.mm.2	Plk1	polo like kinase 1	7	122159434	NM_011121, BC006880 NM_011121, BC006880	18817	147	mitotic sister chromatid segregation G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II establishment of mitotic spindle orientation nucleotide binding mitotic cell cycle mitotic cell cycle mitotic cytokinesis magnesium ion binding chromosome, centromeric region kinetochore kinetochore condensed chromosome, centromeric region chromatin synaptonemal complex spindle pole spindle pole condensed nuclear chromosome outer kinetochore microtubule bundle formation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus chromosome cytoplasm cytoplasm centrosome centrosome centriole spindle cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation cell cycle mitotic spindle assembly checkpoint centrosome cycle regulation of mitotic cell cycle microtubule binding positive regulation of peptidyl-threonine phosphorylation anaphase-promoting complex binding microtubule cytoskeleton kinase activity phosphorylation female meiosis chromosome segregation protein ubiquitination transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding regulation of mitotic metaphase/anaphase transition midbody protein destabilization positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis regulation of cytokinesis protein localization to organelle centriolar satellite polar body extrusion after meiotic divisions identical protein binding negative regulation of apoptotic process regulation of protein binding regulation of protein binding homologous chromosome segregation establishment of protein localization negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of proteolysis nuclear envelope disassembly spindle midzone cell division positive regulation of ubiquitin-protein transferase activity synaptonemal complex disassembly protein localization to chromatin signal transduction involved in G2 DNA damage checkpoint protein localization to nuclear envelope mitotic spindle pole regulation of mitotic spindle assembly positive regulation of ubiquitin protein ligase activity regulation of protein localization to cell cortex	04110 04114 04914
TC0400003366.mm.2	Kif2c	kinesin family member 2C	4	-117159632, -117159635	NM_134471, BC006841 NM_134471, BC006841	73804	32	nucleotide binding chromosome, centromeric region chromosome, centromeric region kinetochore microtubule motor activity ATP binding nucleus chromosome cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule depolymerization cell cycle chromosome segregation mitotic metaphase plate congression microtubule binding microtubule cytoskeleton ATPase activity establishment or maintenance of microtubule cytoskeleton polarity microtubule plus-end microtubule plus-end binding cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore regulation of chromosome segregation
TC1100001219.mm.2	Ccl2	chemokine (C-C motif) ligand 2	11	82035576	NM_011333, BC145867, BC145869 NM_011333, BC145867, BC145869 NM_011333, BC145867, BC145869	20296	908	angiogenesis G protein-coupled receptor binding positive regulation of leukocyte mediated cytotoxicity positive regulation of endothelial cell proliferation leukocyte migration involved in inflammatory response monocyte chemotaxis positive regulation of leukocyte migration positive regulation of cellular extravasation cytokine activity protein binding extracellular region extracellular space extracellular space extracellular space extracellular space cytoplasm rough endoplasmic reticulum cellular calcium ion homeostasis chemotaxis inflammatory response immune response cytoskeleton organization transforming growth factor beta receptor signaling pathway G protein-coupled receptor signaling pathway chemokine activity chemokine activity heparin binding glial cell migration regulation of cell shape response to heat response to wounding response to bacterium regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of macrophage chemotaxis positive regulation of macrophage chemotaxis negative regulation of angiogenesis cytokine-mediated signaling pathway sensory perception of pain positive regulation of cell-cell adhesion endocytic vesicle dendrite neutrophil chemotaxis neutrophil chemotaxis killing of cells of other organism CCR2 chemokine receptor binding positive regulation of tumor necrosis factor production positive regulation of collagen biosynthetic process helper T cell extravasation monocyte homeostasis neuronal cell body perikaryon positive regulation of GTPase activity axon terminus C-fiber synapse positive regulation of cell adhesion vascular endothelial growth factor receptor signaling pathway CCR chemokine receptor binding eosinophil chemotaxis eosinophil chemotaxis macrophage chemotaxis lymphocyte chemotaxis lymphocyte chemotaxis perinuclear region of cytoplasm positive regulation of synaptic transmission positive regulation of T cell activation positive regulation of nitric-oxide synthase biosynthetic process positive regulation of synaptic transmission, glutamatergic antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to interferon-gamma cellular response to interferon-gamma cellular response to interleukin-1 cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to tumor necrosis factor positive regulation of monocyte chemotaxis positive regulation of monocyte chemotaxis positive regulation of immune complex clearance by monocytes and macrophages positive regulation of wound healing positive regulation of protein targeting to membrane positive regulation of NMDA glutamate receptor activity positive regulation of apoptotic cell clearance	04062
TC1300001814.mm.2	F13a1	coagulation factor XIII, A1 subunit	13	-36867177, -36867177	NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274	74145	69	protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity extracellular region cytoplasm blood coagulation blood coagulation hemostasis transferase activity transferase activity, transferring acyl groups peptide cross-linking peptide cross-linking peptide cross-linking metal ion binding collagen-containing extracellular matrix blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation	04610
TC1100004053.mm.2	Cd300ld	CD300 molecule like family member d	11	-114982445	NM_145437, BC019814, CD300-like NM_145437, BC019814, CD300-like NM_145437, BC019814, CD300-like	217305	16	virus receptor activity immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane membrane integral component of membrane regulation of interleukin-6 production regulation of tumor necrosis factor production
TC1900001095.mm.2	Fads2	fatty acid desaturase 2	19	-10062764	NM_019699, BC057189 NM_019699, BC057189	56473	39	stearoyl-CoA 9-desaturase activity endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane linoleoyl-CoA desaturase activity oxidoreductase activity	00592 01040 03320
TC1500001963.mm.2	Nfam1	Nfat activating molecule with ITAM motif 1	15	-82996735, -82996735, -82996735	NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488	74039	14	positive regulation of cytokine production transmembrane signaling receptor activity transmembrane signaling receptor activity transmembrane signaling receptor activity plasma membrane signal transduction signal transduction cell surface membrane integral component of membrane integral component of membrane integral component of membrane B cell differentiation intracellular signal transduction intracellular signal transduction membrane raft membrane raft regulation of B cell differentiation B cell receptor signaling pathway B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity positive regulation of DNA-binding transcription factor activity
TC1800000291.mm.2	Kif20a	kinesin family member 20A	18	34624935, 34624623, 34625032	NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608	19348	33	nucleotide binding mitotic cytokinesis microtubule bundle formation microtubule motor activity ATP binding nucleus nucleoplasm cytoplasm Golgi apparatus spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding protein transport ATPase activity protein kinase binding midbody cleavage furrow regulation of cytokinesis intercellular bridge midbody abscission
TC0800000937.mm.2	Asf1b	anti-silencing function 1B histone chaperone	8	83955693	NM_024184, BC003428 NM_024184, BC003428	66929	23	chromatin chromatin blastocyst hatching nucleus nucleoplasm chromatin organization chromatin assembly or disassembly nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly DNA replication-independent nucleosome assembly protein-containing complex histone binding histone binding
TC1400000322.mm.2	Nt5dc2	5'-nucleotidase domain containing 2	14	31134735, 31131088	NM_027289, BC011230 NM_027289, BC011230	70021	17	cellular_component 5'-nucleotidase activity
TC0100002285.mm.2	Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	1	-45908069	NM_016917, BC003438 NM_016917, BC003438	53945	138	lymphocyte homeostasis endothelium development iron ion transmembrane transporter activity iron ion transmembrane transporter activity iron ion transmembrane transporter activity protein binding nucleoplasm cytosol plasma membrane plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle ferrous iron transmembrane transporter activity membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane peptide hormone binding peptide hormone binding peptide hormone binding regulation of transcription from RNA polymerase II promoter in response to iron iron ion transmembrane transport iron ion transmembrane transport iron ion transmembrane transport identical protein binding negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II spleen development iron ion homeostasis iron ion homeostasis spleen trabecula formation multicellular organismal iron ion homeostasis iron ion export across plasma membrane
TC1100004229.mm.2	Cbr2	carbonyl reductase 2	11	-120729484	NM_007621, BC010758 NM_007621, BC010758	12409	25	carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity protein binding mitochondrion xylulose metabolic process glucose metabolic process NADH oxidation oxidoreductase activity identical protein binding protein self-association L-xylulose reductase (NADP+) activity	00590 01100
TC0800000096.mm.2	Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	8	11758364, 11728057, 11779283, 11728057, 11758364	NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838	54126	81	storage vacuole hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane focal adhesion Golgi organization small GTPase mediated signal transduction nervous system development protein kinase binding protein kinase binding lamellipodium lamellipodium assembly cell junction growth cone small GTPase binding positive regulation of protein binding protein-containing complex regulation of Rho protein signal transduction intracellular signal transduction cell projection neuron projection neuronal cell body positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of GTPase activity positive regulation of GTPase activity astrocyte cell migration positive regulation of growth hormone secretion postsynaptic actin cytoskeleton organization GABA-ergic synapse presynaptic actin cytoskeleton organization regulation of GTP binding	04810
TC0100003029.mm.2	Cxcr4	chemokine (C-X-C motif) receptor 4	1	-128588198	NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322	12767	580	branching involved in blood vessel morphogenesis ameboidal-type cell migration neuron migration neuron migration kidney development positive regulation of protein phosphorylation epithelial cell development ventricular septum development actin binding G protein-coupled receptor activity chemokine receptor activity protein binding nucleus cytoplasm lysosome endosome early endosome late endosome plasma membrane plasma membrane cell-cell junction chemotaxis immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration germ cell development nervous system development brain development brain development motor neuron axon guidance germ cell migration animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface cell surface membrane integral component of membrane cell migration C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling cytokine binding C-C chemokine binding C-C chemokine binding neurogenesis neurogenesis telencephalon cell migration cell junction regulation of cell adhesion regulation of cell migration regulation of cell migration positive regulation of cell migration growth cone cell leading edge cytoplasmic vesicle ubiquitin protein ligase binding myosin light chain binding protein-containing complex positive regulation of vascular wound healing hematopoietic stem cell migration aorta development C-X-C motif chemokine 12 receptor activity CXCL12-activated CXCR4 signaling pathway T cell proliferation identical protein binding regulation of programmed cell death ubiquitin binding myelin maintenance endothelial cell differentiation generation of neurons positive regulation of oligodendrocyte differentiation positive regulation of neurogenesis regulation of viral process regulation of chemotaxis positive regulation of chemotaxis detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain regulation of calcium ion transport cardiac muscle contraction cell chemotaxis endothelial tube morphogenesis neural precursor cell proliferation positive regulation of ERK1 and ERK2 cascade cellular response to cytokine stimulus cellular response to cytokine stimulus positive regulation of calcium ion import positive regulation of cold-induced thermogenesis positive regulation of dendrite extension positive regulation of mesenchymal stem cell migration positive regulation of macrophage migration inhibitory factor signaling pathway	04060 04062 04144 04360 04670 04672
TC0800001247.mm.2	Prmt7	protein arginine N-methyltransferase 7	8	106211053	NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177	214572	42	spliceosomal snRNP assembly fibrillar center protein binding nucleus nucleoplasm cytoplasm cytosol chromatin organization regulation of gene expression by genetic imprinting protein methylation methyltransferase activity histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity [myelin basic protein]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation cell differentiation methylation histone arginine methylation protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity ribonucleoprotein complex binding DNA methylation involved in gamete generation histone methyltransferase activity (H4-R3 specific)
TC1500000175.mm.2					NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379			inorganic phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity plasma membrane integral component of plasma membrane integral component of plasma membrane phosphate ion transport phosphate ion transmembrane transporter activity membrane integral component of membrane integral component of membrane regulation of bone mineralization inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity phosphate ion transmembrane transport
TC0900000051.mm.2	Mmp27	matrix metallopeptidase 27	9	7571395	NM_001030289	234911	12	metalloendopeptidase activity extracellular matrix organization collagen catabolic process extrinsic component of endoplasmic reticulum membrane
TC0100003210.mm.2	Rgs18	regulator of G-protein signaling 18	1	-144752682	NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546	64214	21	GTPase activator activity cytoplasm G protein-coupled receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction
TC0200000603.mm.2	Angptl2	angiopoietin-like 2	2	33215960	NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610	26360	53	angiogenesis signaling receptor binding extracellular region extracellular space extracellular space collagen-containing extracellular matrix
TC0900001173.mm.2	Plscr4	phospholipid scramblase 4	9	92457377	NM_178711, BC052067 NM_178711, BC052067	235527	14	plasma membrane plasma membrane membrane integral component of membrane plasma membrane phospholipid scrambling phospholipid scramblase activity enzyme binding CD4 receptor binding cellular response to lipopolysaccharide
TC1100004057.mm.2					NM_001101656, NM_001101657, BC119352 NM_001101656, NM_001101657, BC119352 NM_001101656, NM_001101657, BC119352			immune system process molecular_function transmembrane signaling receptor activity protein binding cellular_component lysosome endosome plasma membrane biological_process membrane integral component of membrane positive regulation of protein ubiquitination positive regulation of toll-like receptor 9 signaling pathway positive regulation of toll-like receptor 9 signaling pathway
TC0300001378.mm.2	Slc39a8	solute carrier family 39 (metal ion transporter), member 8	3	135825789, 135825656, 135825278	NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731	67547	51	iron ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity lysosome lysosomal membrane plasma membrane plasma membrane integral component of plasma membrane transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated protein N-linked glycosylation arginine metabolic process ion transport cobalt ion transport zinc ion transport cellular cadmium ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cobalt ion transmembrane transporter activity bicarbonate transmembrane transporter activity anion:cation symporter activity bicarbonate transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane metal ion transport cellular manganese ion homeostasis extracellular matrix organization extracellular matrix organization organelle membrane regulation of membrane potential metal ion transmembrane transporter activity transmembrane transport leukocyte adhesion to arterial endothelial cell cadmium ion transmembrane transport cadmium ion transmembrane transport cadmium ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport zinc ion transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane selenite:proton symporter activity plasma membrane selenite transport plasma membrane selenite transport iron ion import across plasma membrane iron ion import across plasma membrane zinc:bicarbonate symporter activity cartilage homeostasis mitochondrial manganese ion transmembrane transport
TC0800000846.mm.2	Mcm5	minichromosome maintenance complex component 5	8	75109508	NM_008566, BC094416 NM_008566, BC094416	17218	41	nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleoplasm chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation cell cycle hydrolase activity single-stranded DNA helicase activity MCM complex MCM complex 3'-5' DNA helicase activity	03030 04110
TC0900001673.mm.2	Ccr3	chemokine (C-C motif) receptor 3	9	124021970	NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968	12771	76	positive regulation of endothelial cell proliferation mast cell chemotaxis G protein-coupled receptor activity chemokine receptor activity protein binding extracellular space cytoplasm endosome plasma membrane chemotaxis inflammatory response immune response signal transduction positive regulation of cytosolic calcium ion concentration external side of plasma membrane membrane integral component of membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding C-C chemokine binding C-C chemokine binding angioblast cell migration positive regulation of angiogenesis positive regulation of angiogenesis eosinophil chemotaxis cell chemotaxis ERK1 and ERK2 cascade	04060 04062
TC0600002690.mm.2	Mcm2	minichromosome maintenance complex component 2	6	-88883473	NM_008564, BC055318 NM_008564, BC055318	17216	82	nucleotide binding double-strand break repair via break-induced replication chromatin DNA binding DNA replication origin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm nuclear origin of replication recognition complex chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA replication initiation nucleosome assembly apoptotic process cell cycle hydrolase activity single-stranded DNA helicase activity enzyme binding histone binding MCM complex MCM complex 3'-5' DNA helicase activity metal ion binding cellular response to interleukin-4 cochlea development mitotic DNA replication initiation negative regulation of DNA helicase activity	03030 04110
TC1600000650.mm.2	Naa50	N(alpha)-acetyltransferase 50, NatE catalytic subunit	16	44139808, 44139790	NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117	72117	26	peptide alpha-N-acetyltransferase activity protein binding nucleus cytoplasm cytoplasm cytoplasm cytosol N-terminal protein amino acid acetylation N-terminal protein amino acid acetylation mitotic sister chromatid cohesion N-acetyltransferase activity H4 histone acetyltransferase activity histone acetylation transferase activity transferase activity, transferring acyl groups NatA complex NatA complex establishment of mitotic sister chromatid cohesion peptidyl-lysine acetyltransferase activity mitotic sister chromatid cohesion, centromeric
TC1100001256.mm.2	Ccl4	chemokine (C-C motif) ligand 4	11	83662583	NM_013652, BC119257, BC119259 NM_013652, BC119257, BC119259 NM_013652, BC119257, BC119259	20303	86	monocyte chemotaxis cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis inflammatory response inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity chemokine activity response to toxic substance neutrophil chemotaxis leukocyte chemotaxis CCR1 chemokine receptor binding CCR5 chemokine receptor binding positive regulation of tumor necrosis factor production cellular response to drug identical protein binding positive regulation of vascular permeability positive regulation of GTPase activity negative regulation by host of viral transcription CCR chemokine receptor binding eosinophil chemotaxis lymphocyte chemotaxis positive regulation of calcium-mediated signaling positive regulation of calcium ion transport chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor positive regulation of natural killer cell chemotaxis	04060 04062 04620 04623
TC1000001207.mm.2	Dusp6	dual specificity phosphatase 6	10	99263230	NM_026268, BC003869 NM_026268, BC003869	67603	165	inactivation of MAPK activity inactivation of MAPK activity negative regulation of protein phosphorylation phosphoprotein phosphatase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding nucleoplasm cytoplasm cytoplasm cytosol cytosol protein dephosphorylation protein dephosphorylation protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity positive regulation of cell death dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-threonine dephosphorylation positive regulation of apoptotic process positive regulation of apoptotic process mitogen-activated protein kinase binding regulation of heart growth regulation of heart growth negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade	04010
TC1300001558.mm.2	H2ac15	H2A clustered histone 15	13	-21753376	NM_178183, BC119335 NM_178183, BC119335	319169	7	nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity	05322
TC1600001011.mm.2	Itsn1	intersectin 1 (SH3 domain protein 1A)	16	91729370, 91729370, 91729370	NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688	16443	71	guanyl-nucleotide exchange factor activity calcium ion binding protein binding nucleus nuclear envelope cytoplasm cytoplasm endosome cytosol plasma membrane plasma membrane clathrin-coated pit clathrin-coated pit clathrin-coated pit exocytosis endocytosis small GTPase mediated signal transduction protein transport membrane endosomal transport kinase activator activity lamellipodium cell junction endocytic vesicle cytoplasmic vesicle cellular protein localization regulation of Rho protein signal transduction intracellular signal transduction presynaptic membrane cell projection neuron projection neuronal cell body dendritic spine negative regulation of neuron apoptotic process calyx of Held synapse metal ion binding synaptic vesicle endocytosis synaptic vesicle endocytosis positive regulation of protein kinase B signaling molecular adaptor activity molecular adaptor activity positive regulation of growth hormone secretion positive regulation of dendritic spine development proline-rich region binding apical dendrite intracellular vesicle intracellular vesicle presynaptic endocytic zone postsynaptic actin cytoskeleton glutamatergic synapse clathrin-dependent synaptic vesicle endocytosis regulation of modification of postsynaptic actin cytoskeleton positive regulation of caveolin-mediated endocytosis
TC1100002224.mm.2	Fignl1	fidgetin-like 1	11	-11800287	NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415	60530	23	nucleotide binding nuclear chromosome osteoblast differentiation ATP binding nucleus nucleus cytoplasm male meiotic nuclear division microtubule-severing ATPase activity regulation of double-strand break repair via homologous recombination hydrolase activity ATPase activity cytoplasmic microtubule organization osteoblast proliferation negative regulation of apoptotic process metal ion binding perinuclear region of cytoplasm regulation of cell cycle cellular response to ionizing radiation negative regulation of intrinsic apoptotic signaling pathway
TC0800000126.mm.2	Tfdp1	transcription factor Dp 1	8	13338803, 13338750	NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344	21781	62	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II cell cycle transcription factor binding epidermis development protein domain specific binding anoikis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of DNA-binding transcription factor activity regulation of cell cycle negative regulation of fat cell proliferation RNA polymerase II transcription regulator complex positive regulation of G1/S transition of mitotic cell cycle regulation of DNA biosynthetic process	04110 04350
TC1500001940.mm.2	Cenpm	centromere protein M	15	-82233775, -82233775	NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160	66570	19	chromosome, centromeric region kinetochore molecular_function nucleus chromosome cytoplasm cytosol biological_process
TC0500000052.mm.2	Abcb1b	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	5	8798146	NM_011075, BC141363, BC150811 NM_011075, BC141363, BC150811 NM_011075, BC141363, BC150811	18669	256	Golgi membrane nucleotide binding ATP binding mitochondrion plasma membrane establishment of endothelial blood-brain barrier membrane integral component of membrane apical plasma membrane ATPase activity response to drug ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity phospholipid translocation intercellular canaliculus transmembrane transport Sertoli cell barrier remodeling phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity external side of apical plasma membrane ceramide floppase activity ceramide translocation	02010 04976
TC1300000246.mm.2	H3c8	H3 clustered histone 8	13	23535417	NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357	97908	28	nuclear chromosome nucleosome nucleus nucleoplasm nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC1000003119.mm.2	Lrp1	low density lipoprotein receptor-related protein 1	10	-127538157	NM_008512	16971	324	protease binding astrocyte activation involved in immune response cardiac septum development calcium ion binding protein binding nucleus cytoplasm endosome early endosome Golgi apparatus cytoskeleton plasma membrane integral component of plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis phagocytosis lysosomal transport positive regulation of cytosolic calcium ion concentration protein kinase C-activating G protein-coupled receptor signaling pathway multicellular organism development cholesterol metabolic process cell population proliferation external side of plasma membrane negative regulation of cell-substrate adhesion positive regulation of cholesterol efflux positive regulation of cell death positive regulation of neuron projection development negative regulation of neuron projection development negative regulation of smooth muscle cell migration coreceptor activity membrane integral component of membrane basolateral plasma membrane alpha-2 macroglobulin receptor activity cell junction clathrin-coated vesicle negative regulation of Wnt signaling pathway dendrite clathrin heavy chain binding positive regulation of protein binding positive regulation of lipid transport regulation of cholesterol transport regulation of phospholipase A2 activity insulin-responsive compartment regulation of actin cytoskeleton organization apolipoprotein binding positive regulation of insulin secretion involved in cellular response to glucose stimulus aorta morphogenesis cargo receptor activity cargo receptor activity neuronal cell body negative regulation of apoptotic process receptor complex apoptotic cell clearance negative regulation of neuron apoptotic process cellular lipid catabolic process axonal growth cone protein-containing complex binding apical part of cell synapse positive regulation of axon extension positive regulation of endocytosis metal ion binding perinuclear region of cytoplasm positive regulation of axon extension involved in regeneration positive regulation of collateral sprouting of injured axon positive regulation of phagocytosis positive regulation of protein transport negative regulation of cytosolic calcium ion concentration negative regulation of focal adhesion assembly negative regulation of cell death coronary vasculature development chemoattraction of axon positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process transport across blood-brain barrier positive regulation of Schwann cell migration positive regulation of amyloid-beta clearance positive regulation of protein localization to plasma membrane positive regulation of cholesterol import positive regulation of transcytosis cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell migration positive regulation of lysosomal protein catabolic process positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of platelet-derived growth factor receptor-beta signaling pathway	05010 05144
TC0200001748.mm.2	Knstrn	kinetochore-localized astrin/SPAG5 binding	2	118814002	NM_026412, BC031709 NM_026412, BC031709	51944	22	mitotic sister chromatid segregation mitotic sister chromatid segregation microtubule cytoskeleton organization chromosome, centromeric region kinetochore kinetochore ruffle protein binding nucleus chromosome cytoplasm cytoskeleton microtubule plasma membrane cell cycle spindle organization spindle organization chromosome segregation cell migration centriolar satellite centriolar satellite microtubule plus-end microtubule plus-end protein homodimerization activity microtubule plus-end binding cell division regulation of attachment of spindle microtubules to kinetochore regulation of attachment of spindle microtubules to kinetochore cellular response to epidermal growth factor stimulus mitotic spindle mitotic spindle
TC0600001443.mm.2	Lpar5	lysophosphatidic acid receptor 5	6	125067919, 125071334	NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528	381810	39	G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane positive regulation of CREB transcription factor activity positive regulation of CREB transcription factor activity behavioral response to pain behavioral response to pain
TC0300000934.mm.2	H3c13	H3 clustered histone 13	3	96268653	NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965	319154	5	nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC0200000245.mm.2	Mrc1	mannose receptor, C type 1	2	14229413	NM_008625, BC141338 NM_008625, BC141338	17533	108	transmembrane signaling receptor activity protein binding mannose binding endosome plasma membrane plasma membrane plasma membrane endocytosis receptor-mediated endocytosis receptor-mediated endocytosis cell surface endosome membrane membrane integral component of membrane carbohydrate binding signaling receptor activity cargo receptor activity cellular response to lipopolysaccharide cellular response to interferon-gamma cellular response to interleukin-4	04145
TC0900002593.mm.2	Ccnb2	cyclin B2	9	-70407688	NM_007630, BC008247 NM_007630, BC008247	12442	54	regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex in utero embryonic development protein binding nucleus cytoplasm cytoplasm centrosome centrosome cytosol cell cycle spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I G2/MI transition of meiotic cell cycle G2/MI transition of meiotic cell cycle microtubule cytoskeleton membrane cyclin-dependent protein serine/threonine kinase regulator activity regulation of growth T cell homeostasis mitotic cell cycle phase transition thymus development cell division	04110 04114 04115 04914
TC0700002422.mm.2	C5ar1	complement component 5a receptor 1	7	-16246742, -16246744	NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643	12273	256	microglial cell activation complement component C5a binding complement receptor mediated signaling pathway complement receptor activity complement component C5a receptor activity complement component C5a receptor activity complement component C5a receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane apoptotic process chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell surface positive regulation of vascular endothelial growth factor production positive regulation of macrophage chemotaxis membrane integral component of membrane basolateral plasma membrane cell proliferation in hindbrain neutrophil chemotaxis cytoplasmic vesicle response to peptidoglycan complement component C5a signaling pathway mRNA transcription by RNA polymerase II negative regulation of neuron apoptotic process apical part of cell positive regulation of angiogenesis astrocyte activation positive regulation of epithelial cell proliferation defense response to Gram-positive bacterium cognition positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis amyloid-beta clearance presynapse organization regulation of tau-protein kinase activity	04080 04610 05150
TC1300000262.mm.2	H1f1	H1.1 linker histone, cluster member	13	23763667	NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850	80838	42	nucleosome DNA binding double-stranded DNA binding protein binding nucleus nucleus chromosome nucleosome assembly spermatogenesis spermatogenesis heparin binding cell surface nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing vesicle negative regulation of DNA recombination positive regulation of receptor-mediated endocytosis
TC1300002037.mm.2	Cltb	clathrin, light polypeptide (Lcb)	13	-54592385	NM_028870, BC070404 NM_028870, BC070404	74325	32	structural molecule activity trans-Golgi network cytosol plasma membrane plasma membrane plasma membrane clathrin-coated pit intracellular protein transport membrane vesicle-mediated transport clathrin coat clathrin vesicle coat clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle clathrin heavy chain binding peptide binding intracellular membrane-bounded organelle clathrin coat assembly ciliary membrane clathrin-dependent endocytosis presynaptic endocytic zone membrane postsynaptic endocytic zone cytoplasmic component	04142 04144 05016 05100
TC1000001066.mm.2	Igf1	insulin-like growth factor 1	10	87861110, 87859051, 87858264	NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052	16000	992	activation of MAPK activity osteoblast differentiation cell activation regulation of protein phosphorylation blood vessel remodeling blood vessel remodeling negative regulation of immune system process insulin receptor binding insulin receptor binding insulin-like growth factor receptor binding insulin-like growth factor receptor binding integrin binding hormone activity steroid binding protein binding extracellular region interstitial matrix extracellular space extracellular space extracellular space cytoplasm plasma membrane regulation of translation nervous system development sensory perception of smell memory circadian rhythm growth factor activity cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation response to heat glial cell differentiation regulation of gene expression positive regulation of glycoprotein biosynthetic process positive regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression negative regulation of muscle cell apoptotic process phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration muscle hypertrophy myotube cell development positive regulation of smooth muscle cell migration positive regulation of cerebellar granule cell precursor proliferation water homeostasis proteoglycan biosynthetic process positive regulation of cell growth lung development positive regulation of cell migration mammary gland development exocrine pancreas development platelet alpha granule positive regulation of myelination activation of protein kinase B activity negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production regulation of establishment or maintenance of cell polarity regulation of intracellular steroid hormone receptor signaling pathway negative regulation of smooth muscle cell apoptotic process multicellular organism growth bone mineralization involved in bone maturation alphav-beta3 integrin-IGF-1-IGF1R complex wound healing positive regulation of activated T cell proliferation regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein insulin-like growth factor ternary complex insulin-like growth factor ternary complex neuronal cell body negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of DNA binding positive regulation of MAPK cascade protein kinase B signaling positive regulation of blood vessel endothelial cell migration protein serine/threonine kinase activator activity positive regulation of insulin-like growth factor receptor signaling pathway regulation of nitric oxide biosynthetic process myoblast differentiation response to ethanol positive regulation of fat cell differentiation positive regulation of osteoblast differentiation positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of mitotic nuclear division positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of glucose import positive regulation of Ras protein signal transduction insulin-like growth factor receptor signaling pathway insulin-like growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of fibroblast proliferation lung alveolus development lung alveolus development cell development positive regulation of smooth muscle cell proliferation branching morphogenesis of an epithelial tube inner ear development chondroitin sulfate proteoglycan biosynthetic process positive regulation of epithelial cell proliferation positive regulation of protein secretion positive regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation protein stabilization detection of mechanical stimulus involved in sensory perception regulation of protein metabolic process myoblast proliferation positive regulation of protein kinase B signaling regulation of calcium ion transport positive regulation of glial cell proliferation negative regulation of oocyte development lung vasculature development lung vasculature development lung lobe morphogenesis lung lobe morphogenesis type I pneumocyte differentiation type II pneumocyte differentiation prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis prostate gland growth prostate gland growth prostate gland epithelium morphogenesis prostate gland stromal morphogenesis negative regulation of androgen receptor signaling pathway positive regulation of cell growth involved in cardiac muscle cell development ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade exocytic vesicle positive regulation of calcineurin-NFAT signaling cascade cellular response to glucose stimulus positive regulation of protein serine/threonine kinase activity positive regulation of steroid hormone biosynthetic process negative regulation of release of cytochrome c from mitochondria extrinsic apoptotic signaling pathway in absence of ligand negative regulation of neuroinflammatory response negative regulation of oligodendrocyte apoptotic process negative regulation of neuron death negative regulation of amyloid-beta formation positive regulation of trophectodermal cell proliferation negative regulation of cholangiocyte apoptotic process cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process positive regulation of vascular endothelial cell proliferation cellular response to insulin-like growth factor stimulus positive regulation of myoblast proliferation positive regulation of transcription regulatory region DNA binding negative regulation of extrinsic apoptotic signaling pathway	04114 04115 04150 04510 04730 04914 04960 05200 05214 05215 05218 05410 05414
TC0100001985.mm.2	Eya1	EYA transcriptional coactivator and phosphatase 1	1	-14168957	NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860	14048	151	establishment of mitotic spindle orientation establishment of mitotic spindle orientation metanephros development ureteric bud development branching involved in ureteric bud morphogenesis outflow tract morphogenesis RNA binding phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm DNA repair double-strand break repair chromatin organization protein dephosphorylation cellular response to DNA damage stimulus multicellular organism development pattern specification process pattern specification process mesodermal cell fate specification animal organ morphogenesis response to ionizing radiation striated muscle tissue development histone dephosphorylation histone dephosphorylation nuclear body hydrolase activity protein sumoylation cell differentiation protein-containing complex protein-DNA complex cellular protein localization establishment or maintenance of apical/basal cell polarity peptidyl-tyrosine dephosphorylation aorta morphogenesis ear morphogenesis inner ear morphogenesis inner ear morphogenesis outer ear morphogenesis middle ear morphogenesis cell fate commitment regulation of neuron differentiation regulation of neuron differentiation positive regulation of DNA repair positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding neuron fate specification embryonic skeletal system morphogenesis semicircular canal morphogenesis anatomical structure development anatomical structure development positive regulation of epithelial cell proliferation pharyngeal system development lung epithelial cell differentiation otic vesicle development otic vesicle morphogenesis positive regulation of secondary heart field cardioblast proliferation cochlea morphogenesis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
TC0X00003241.mm.2	Ptchd1	patched domain containing 1	X	-155569735	NM_001093750, BC116312, BC116313 NM_001093750, BC116312, BC116313 NM_001093750, BC116312, BC116313	211612	18	protein binding plasma membrane plasma membrane smoothened signaling pathway chemical synaptic transmission short-term memory long-term memory membrane integral component of membrane thalamus development social behavior synapse synapse cognition cognition cognition excitatory chemical synaptic transmission inhibitory chemical synaptic transmission
TC0100001550.mm.2	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	1	167349990	NM_019993, BC003297 NM_019993, BC003297	56752	27	aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase (NAD+) activity cytoplasm mitochondrion cytosol cytosol cellular aldehyde metabolic process carnitine metabolic process oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor aminobutyraldehyde dehydrogenase activity aminobutyraldehyde dehydrogenase activity neurotransmitter biosynthetic process identical protein binding amine binding 4-trimethylammoniobutyraldehyde dehydrogenase activity 4-trimethylammoniobutyraldehyde dehydrogenase activity NAD binding protein homotetramerization	00010 00053 00071 00280 00310 00330 00340 00380 00410 00561 00620 00640 01100
TC0900000046.mm.2	Mmp12	matrix metallopeptidase 12	9	7347373, 7344396	NM_008605, BC019135 NM_008605, BC019135	17381	159	negative regulation of transcription by RNA polymerase II core promoter sequence-specific DNA binding metalloendopeptidase activity metalloendopeptidase activity calcium ion binding collagen binding extracellular region extracellular region extracellular space extracellular space extracellular space nucleus nucleus cytoplasm proteolysis protein import into nucleus protein import into nucleus peptidase activity metallopeptidase activity zinc ion binding positive regulation of gene expression hydrolase activity extracellular matrix organization collagen catabolic process extracellular matrix positive regulation of interferon-alpha production wound healing, spreading of epidermal cells wound healing sequence-specific DNA binding positive regulation of transcription by RNA polymerase II metal ion binding lung alveolus development regulation of defense response to virus by host positive regulation of epithelial cell proliferation involved in wound healing elastin catabolic process negative regulation of type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway bronchiole development bronchiole development cellular response to virus regulation of trophoblast cell migration negative regulation of endothelial cell-matrix adhesion via fibronectin
TC0300001137.mm.2	Sort1	sortilin 1	3	108284063	NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343	20661	120	ossification protein binding nucleus lysosome endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein targeting to lysosome post-Golgi vesicle-mediated transport Golgi to endosome transport Golgi to endosome transport endocytosis endocytosis endocytosis G protein-coupled receptor signaling pathway neuropeptide signaling pathway multicellular organism development endosome to lysosome transport extrinsic apoptotic signaling pathway via death domain receptors cell surface endosome membrane nerve growth factor receptor activity regulation of gene expression myotube differentiation myotube differentiation membrane integral component of membrane integral component of membrane vesicle organization vesicle organization vesicle organization enzyme binding clathrin-coated vesicle trans-Golgi network transport vesicle cell differentiation neurotensin receptor activity, non-G protein-coupled dendrite cytoplasmic vesicle membrane cytoplasmic vesicle endosome transport via multivesicular body sorting pathway response to insulin response to insulin neuronal cell body intracellular membrane-bounded organelle negative regulation of fat cell differentiation glucose import glucose import neurotrophin TRK receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity Golgi to lysosome transport positive regulation of epithelial cell apoptotic process retromer complex binding	04142 04722
TC0100003069.mm.2	Cdk18	cyclin-dependent kinase 18	1	-132113546	NM_008795, BC119617 NM_008795, BC119617	18557	20	regulation of transcription involved in G1/S transition of mitotic cell cycle nucleotide binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein phosphorylation kinase activity phosphorylation transferase activity
TC1100004058.mm.2					NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300			immune system process molecular_function transmembrane signaling receptor activity protein binding cellular_component lysosome endosome plasma membrane biological_process membrane integral component of membrane positive regulation of protein ubiquitination positive regulation of toll-like receptor 9 signaling pathway positive regulation of toll-like receptor 9 signaling pathway
TC0300001856.mm.2	Ccna2	cyclin A2	3	-36564864	NM_009828, BC052730 NM_009828, BC052730	12428	199	regulation of cyclin-dependent protein serine/threonine kinase activity G2/M transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex female pronucleus male pronucleus protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm cytosol regulation of DNA replication cell cycle cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity histone phosphorylation protein kinase binding protein kinase binding protein domain specific binding mitotic cell cycle phase transition cell cycle G1/S phase transition positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fibroblast proliferation cell division cyclin A2-CDK2 complex cyclin A2-CDK2 complex cyclin A2-CDK2 complex	04110 04914
TC1300001837.mm.2	Eef1e1	eukaryotic translation elongation factor 1 epsilon 1	13	-38645690	NM_025380, BC048466 NM_025380, BC048466	66143	27	protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol translation negative regulation of cell population proliferation aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex positive regulation of apoptotic process positive regulation of DNA damage response, signal transduction by p53 class mediator cellular response to leukemia inhibitory factor positive regulation of cellular senescence positive regulation of apoptotic signaling pathway
TC0300002313.mm.2	Lmna	lamin A	3	-88481147, -88483204, -88483204	NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020	16905	327	protein binding nucleus nucleus nuclear envelope nuclear envelope nuclear envelope lamin filament nucleoplasm nucleoplasm cytosol intermediate filament protein import into nucleus nucleus organization nucleus organization nuclear envelope organization nuclear envelope organization muscle organ development protein phosphatase 1 binding negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix nuclear body nuclear speck establishment of cell polarity regulation of cell migration establishment or maintenance of microtubule cytoskeleton polarity regulation of protein stability nuclear membrane regulation of telomere maintenance protein localization to nucleus cellular protein localization site of double-strand break identical protein binding positive regulation of osteoblast differentiation perinuclear region of cytoplasm ventricular cardiac muscle cell development negative regulation of mesenchymal cell proliferation negative regulation of release of cytochrome c from mitochondria positive regulation of cell aging positive regulation of histone H3-K9 trimethylation negative regulation of cardiac muscle hypertrophy in response to stress negative regulation of adipose tissue development DNA double-strand break attachment to nuclear envelope negative regulation of extrinsic apoptotic signaling pathway	05410 05412 05414
TC1200000664.mm.2	Rhoj	ras homolog family member J	12	75308312	NM_023275, BC043719 NM_023275, BC043719	80837	34	nucleotide binding angiogenesis GTPase activity GTPase activity GTPase activity protein binding GTP binding GTP binding intracellular anatomical structure plasma membrane endocytosis small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape regulation of endothelial cell migration membrane cell migration cell projection assembly actin cytoskeleton organization actin cytoskeleton organization Cdc42 protein signal transduction retina vasculature morphogenesis in camera-type eye positive regulation of cell migration involved in sprouting angiogenesis regulation of sprouting angiogenesis
TC1100001592.mm.2	Igfbp4	insulin-like growth factor binding protein 4	11	99041243	NM_010517, BC019836 NM_010517, BC019836	16010	101	regulation of cell growth protein binding insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space regulation of glucose metabolic process growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding regulation of growth positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation
TC0300000656.mm.2	Tmem154	transmembrane protein 154	3	84666191	NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175	320782	11	molecular_function cellular_component biological_process membrane integral component of membrane
TC1900001498.mm.2	Blnk	B cell linker	19	-40928926	NM_008528, BC059785 NM_008528, BC059785	17060	107	protein binding cytoplasm cytoplasm cytosol plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of gene expression membrane enzyme binding intracellular signal transduction intracellular signal transduction signaling adaptor activity cytoplasmic ribonucleoprotein granule B cell activation SH2 domain binding B cell receptor signaling pathway protein tyrosine kinase binding	04380 04662 05340
TC1300001633.mm.2	H3c6	H3 clustered histone 6	13	-23561474	NM_178205, BC156786 NM_178205, BC156786	319151	11	nuclear chromosome chromatin nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC1300001561.mm.2	H3c11	H3 clustered histone 11	13	-21782914	NM_178207, BC116383 NM_178207, BC116383	319153	10	nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC1000002453.mm.2	Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase	10	-78436746	NM_172134, BC027745 NM_172134, BC027745	216134	31	nucleotide binding magnesium ion binding ATP binding nucleoplasm cytoplasm cytosol zinc ion binding pyridoxal kinase activity pyridoxal kinase activity pyridoxal 5'-phosphate salvage pyridoxal 5'-phosphate salvage kinase activity phosphorylation transferase activity pyridoxal phosphate binding potassium ion binding sodium ion binding lithium ion binding small molecule binding protein homodimerization activity pyridoxal phosphate biosynthetic process negative regulation of apoptotic process metal ion binding pyridoxal binding	00750 01100
TC1200001324.mm.2	Cdca7l	cell division cycle associated 7 like	12	117843860	NM_146040, BC006933 NM_146040, BC006933	217946	19	fibrillar center nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol regulation of transcription, DNA-templated positive regulation of cell population proliferation
TC0800000955.mm.2	Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	8	84415363	NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578	12286	343	regulation of neurotransmitter levels ion channel activity voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity calcium channel activity protein binding calmodulin binding nucleus cytoplasm plasma membrane voltage-gated calcium channel complex voltage-gated calcium channel complex ion transport calcium ion transport calcium ion transport calcium ion transport positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration gamma-aminobutyric acid signaling pathway chemical synaptic transmission chemical synaptic transmission chemical synaptic transmission neuron-neuron synaptic transmission neuromuscular synaptic transmission synapse assembly adult walking behavior adult walking behavior cell death high voltage-gated calcium channel activity high voltage-gated calcium channel activity high voltage-gated calcium channel activity regulation of hormone levels gamma-aminobutyric acid secretion regulation of acetylcholine secretion, neurotransmission membrane integral component of membrane calcium-ion regulated exocytosis regulation of calcium ion-dependent exocytosis transmission of nerve impulse sensory perception of pain syntaxin binding spinal cord motor neuron differentiation cerebellum maturation cerebellar molecular layer development cerebellar Purkinje cell layer development cerebellar Purkinje cell differentiation vestibular nucleus development central nervous system neuron differentiation dendrite cellular chloride ion homeostasis regulation of sulfur amino acid metabolic process negative regulation of hormone biosynthetic process protein-containing complex regulation of ion transmembrane transport synaptic transmission, glutamatergic regulation of membrane potential glucose homeostasis cell projection neuronal cell body neuronal cell body receptor clustering perikaryon negative regulation of neuron apoptotic process metal ion binding response to pain behavioral response to pain calcium ion-regulated exocytosis of neurotransmitter dendrite morphogenesis regulation of axonogenesis modulation of chemical synaptic transmission nervous system process musculoskeletal movement, spinal reflex action neuromuscular process controlling balance neuromuscular process neuromuscular process membrane depolarization transmembrane transport rhythmic synaptic transmission calcium ion import calcium ion import calcium ion transmembrane transport glutamatergic synapse glutamatergic synapse integral component of presynaptic active zone membrane voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels regulation of voltage-gated calcium channel activity response to amyloid-beta cellular response to amyloid-beta	04010 04020 04730 04742 04930
TC1900000152.mm.2	Wdr74	WD repeat domain 74	19	8735838	NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478	107071	21	nuclear exosome (RNase complex) blastocyst formation molecular_function nucleus nucleus nucleoplasm nucleolus nucleolus rRNA processing RNA metabolic process preribosome, large subunit precursor ribosomal large subunit biogenesis ribosomal large subunit biogenesis
TC1000002650.mm.2	Utp20	UTP20 small subunit processome component	10	-88746606	NM_175158	70683	20	nucleus nucleolus nucleolus plasma membrane rRNA processing 90S preribosome small-subunit processome
TC1200001990.mm.2	Actn1	actinin, alpha 1	12	-80167541	NM_134156, BC054830 NM_134156, BC054830	109711	100	stress fiber stress fiber stress fiber ruffle ruffle double-stranded RNA binding actin binding integrin binding integrin binding calcium ion binding protein binding cytoskeletal regulatory protein binding nucleus cytoplasm cytoskeleton actin filament plasma membrane brush border cell-cell junction fascia adherens focal adhesion focal adhesion actin filament organization membrane vinculin binding vinculin binding protein domain specific binding sarcomere Z disc Z disc cell junction secretory granule platelet formation nuclear receptor coactivator activity cortical cytoskeleton cortical actin cytoskeleton cortical cytoskeleton organization dense core granule membrane platelet morphogenesis protein homodimerization activity protein homodimerization activity cell projection dendritic spine ion channel binding metal ion binding focal adhesion assembly synapse organization actin filament binding actin filament binding actin filament bundle assembly negative regulation of cellular component movement actin filament network formation actin crosslink formation glutamatergic synapse postsynapse organization structural constituent of postsynapse	04510 04520 04530 04670 04810 05146 05322 05412
TC1900001266.mm.2	Mamdc2	MAM domain containing 2	19	-23302608	NM_174857, BC042773 NM_174857, BC042773	71738	14	glycosaminoglycan binding extracellular region interstitial matrix endoplasmic reticulum membrane peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix
TC1900000491.mm.2	Lipn	lipase, family member N	19	34067357	NM_027340	70166	12	extracellular region lipid metabolic process lipid catabolic process hydrolase activity hydrolase activity, acting on ester bonds intracellular membrane-bounded organelle
TC0600000324.mm.2	Akr1b8	aldo-keto reductase family 1, member B8	6	34354145	NM_008012, BC005789 NM_008012, BC005789	14187	23	retinoid metabolic process retinal dehydrogenase activity alditol:NADP+ 1-oxidoreductase activity cytoplasm mitochondrion cytosol alcohol dehydrogenase (NADP+) activity farnesol catabolic process oxidoreductase activity daunorubicin metabolic process doxorubicin metabolic process geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity cellular detoxification of aldehyde	00040 00051 00052 00561 00620 01100
TC0100003522.mm.2	Fcgr2b	Fc receptor, IgG, low affinity IIb	1	-170960558	NM_001077189, NM_010187, BC038070 NM_001077189, NM_010187, BC038070 NM_001077189, NM_010187, BC038070	14130	472	amyloid-beta binding negative regulation of type I hypersensitivity immune complex clearance negative regulation of immunoglobulin production negative regulation of inflammatory response to antigenic stimulus negative regulation of acute inflammatory response to antigenic stimulus negative regulation of humoral immune response mediated by circulating immunoglobulin transmembrane signaling receptor activity protein binding extracellular region cytoplasm cytoskeleton plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane integral component of plasma membrane receptor-mediated endocytosis phagocytosis, engulfment defense response cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane cell surface membrane integral component of membrane immunoglobulin mediated immune response dendrite development low-affinity IgG receptor activity IgG binding IgG binding immunoglobulin binding antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation endocytic recycling negative regulation of interleukin-10 production negative regulation of neutrophil apoptotic process Fc-gamma receptor signaling pathway involved in phagocytosis dendritic spine cell body protein-containing complex binding membrane raft positive regulation of JNK cascade regulation of long-term neuronal synaptic plasticity negative regulation of phagocytosis positive regulation of phagocytosis regulation of immune response negative regulation of immune response negative regulation of B cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity recycling endosome cellular response to molecule of bacterial origin positive regulation of neuron death positive regulation of neuron death regulation of dendritic spine maintenance regulation of dendritic spine maintenance cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of response to endoplasmic reticulum stress positive regulation of response to endoplasmic reticulum stress	04145 04380 04662 04666 05150 05322
TC1000003117.mm.2	Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	10	-127517122	NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396	108037	33	translation repressor activity, mRNA regulatory element binding regulation of oxidative phosphorylation regulation of oxidative phosphorylation regulation of oxidative phosphorylation chromatin binding catalytic activity glycine hydroxymethyltransferase activity glycine hydroxymethyltransferase activity nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial intermembrane space mitochondrial matrix mitochondrial matrix cytosol glycine metabolic process glycine biosynthetic process L-serine metabolic process L-serine biosynthetic process L-serine catabolic process one-carbon metabolic process one-carbon metabolic process zinc ion binding positive regulation of cell population proliferation L-allo-threonine aldolase activity purine nucleobase biosynthetic process microtubule cytoskeleton membrane amino acid binding transferase activity glycine biosynthetic process from serine glycine biosynthetic process from serine pyridoxal phosphate binding pyridoxal phosphate binding response to type I interferon response to type I interferon tetrahydrofolate interconversion mitochondrial nucleoid identical protein binding protein homodimerization activity tetrahydrofolate metabolic process tetrahydrofolate metabolic process folic acid metabolic process mRNA 5'-UTR binding cobalt ion binding protein tetramerization protein homotetramerization protein homotetramerization regulation of mitochondrial translation regulation of mitochondrial translation protein K63-linked deubiquitination BRISC complex BRISC complex serine binding regulation of aerobic respiration regulation of aerobic respiration	00260 00460 00670 01100
TC1400000940.mm.2	Pbk	PDZ binding kinase	14	65805910	NM_023209, BC020099 NM_023209, BC020099	52033	33	nucleotide binding mitotic cell cycle negative regulation of protein phosphorylation protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of stress-activated MAPK cascade cellular response to UV negative regulation of inflammatory response
TC0100002033.mm.2	Mcm3	minichromosome maintenance complex component 3	1	-20802967	NM_008563, BC031700 NM_008563, BC031700	17215	65	nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytoplasm centrosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex perinuclear region of cytoplasm mitotic DNA replication initiation	03030 04110
TC0300002284.mm.2	Fcrls	Fc receptor-like S, scavenger receptor	3	-87250964	NM_030707, BC016551 NM_030707, BC016551	80891	22	transmembrane signaling receptor activity integral component of plasma membrane cell surface receptor signaling pathway
TC1700001622.mm.2					NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662			regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex re-entry into mitotic cell cycle placenta development nucleus nucleus cytoplasm centrosome centrosome centriole cytoskeleton cell cycle negative regulation of centrosome duplication negative regulation of centrosome duplication cyclin-dependent protein serine/threonine kinase regulator activity protein ubiquitination SCF ubiquitin ligase complex cell junction SCF-dependent proteasomal ubiquitin-dependent protein catabolic process mitotic cell cycle phase transition cell division regulation of cell cycle
TC1300000181.mm.2					NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162			nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity
TC1300001565.mm.2					NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162			nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity
TC0800000564.mm.2	Dctd	dCMP deaminase	8	48109957, 48110012, 48099091	NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719	320685	16	catalytic activity dCMP deaminase activity pyrimidine nucleotide metabolic process dUMP biosynthetic process dTMP biosynthetic process metabolic process zinc ion binding nucleotide biosynthetic process hydrolase activity identical protein binding metal ion binding	00240 01100
TC0100002576.mm.2	Tns1	tensin 1	1	-73910231	NM_001289895, NM_027884 NM_001289895, NM_027884	21961	27	actin binding focal adhesion focal adhesion cell-substrate junction assembly fibroblast migration cell-substrate junction
TC0100001387.mm.2					NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086			nucleotide binding magnesium ion binding angiogenesis catalytic activity glutamate-ammonia ligase activity glutamate-ammonia ligase activity protein binding ATP binding cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion endoplasmic reticulum rough endoplasmic reticulum cytosol plasma membrane glutamate metabolic process glutamine biosynthetic process glutamine biosynthetic process nitrogen compound metabolic process cell population proliferation cellular response to starvation response to glucose regulation of endothelial cell migration regulation of endothelial cell migration membrane glutamate binding transferase activity ligase activity protein palmitoylation ammonia assimilation cycle protein-cysteine S-palmitoyltransferase activity manganese ion binding positive regulation of insulin secretion protein-containing complex ribosome biogenesis identical protein binding cell projection neuron projection perikaryon myelin sheath myelin sheath intracellular membrane-bounded organelle axon terminus cell body dynein light chain binding metal ion binding positive regulation of epithelial cell proliferation positive regulation of synaptic transmission, glutamatergic glial cell projection regulation of sprouting angiogenesis regulation of sprouting angiogenesis regulation of protein localization to nucleolus
TC0100003697.mm.2	Lbr	lamin B receptor	1	-181815314	NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522	98386	67	DNA binding protein binding nucleus nuclear envelope nuclear envelope nuclear inner membrane nuclear inner membrane nuclear pore nuclear lamina cytoplasm endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process nuclear localization sequence binding steroid metabolic process cholesterol metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor neutrophil differentiation nuclear membrane nuclear membrane delta14-sterol reductase activity delta14-sterol reductase activity chaperone binding chromo shadow domain binding NADPH binding
TC0500003632.mm.2	Slc46a3	solute carrier family 46, member 3	5	-147875897	NM_027872, BC006902 NM_027872, BC006902	71706	18	membrane integral component of membrane transmembrane transporter activity vacuolar transmembrane transport transmembrane transport integral component of lysosomal membrane
TC1700000937.mm.2	Trem2	triggering receptor expressed on myeloid cells 2	17	48346400	NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784	83433	169	lipopolysaccharide binding amyloid-beta binding microglial cell activation microglial cell activation positive regulation of protein phosphorylation microglial cell activation involved in immune response positive regulation of antigen processing and presentation of peptide antigen via MHC class II response to ischemia transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding phospholipid binding extracellular region plasma membrane plasma membrane plasma membrane integral component of plasma membrane phagocytosis, engulfment phagocytosis, engulfment high-density lipoprotein particle binding lipid binding regulation of gene expression regulation of gene expression negative regulation of autophagy negative regulation of autophagy positive regulation of gene expression positive regulation of mitochondrion organization membrane integral component of membrane low-density lipoprotein particle binding osteoclast differentiation intrinsic component of plasma membrane lipopolysaccharide-mediated signaling pathway regulation of TOR signaling positive regulation of TOR signaling detection of lipopolysaccharide detection of peptidoglycan regulation of interleukin-6 production negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production positive regulation of interleukin-10 production apolipoprotein binding apolipoprotein A-I binding very-low-density lipoprotein particle binding positive regulation of macrophage fusion signaling receptor activity defense response to bacterium peptidoglycan binding negative regulation of apoptotic process apoptotic cell clearance plasma membrane raft protein-containing complex binding innate immune response regulation of innate immune response positive regulation of osteoclast differentiation astrocyte activation positive regulation of protein secretion regulation of peptidyl-tyrosine phosphorylation regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of calcium-mediated signaling positive regulation of chemotaxis regulation of resting membrane potential positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment microglial cell proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid lipoteichoic acid binding cellular response to lipoteichoic acid cellular response to peptidoglycan regulation of macrophage inflammatory protein 1 alpha production lipoprotein particle binding dendritic cell differentiation scaffold protein binding amyloid-beta clearance import into cell regulation of plasma membrane bounded cell projection organization regulation of plasma membrane bounded cell projection organization regulation of plasma membrane bounded cell projection organization complement-mediated synapse pruning neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of amyloid-beta clearance positive regulation of engulfment of apoptotic cell positive regulation of NIK/NF-kappaB signaling positive regulation of proteasomal protein catabolic process positive regulation of inward rectifier potassium channel activity regulation of intracellular signal transduction positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of microglial cell activation positive regulation of microglial cell activation positive regulation of microglial cell activation negative regulation of autophagic cell death positive regulation of microglial cell migration positive regulation of microglial cell migration cellular response to amyloid-beta positive regulation of CAMKK-AMPK signaling cascade protein tyrosine kinase binding positive regulation of CD40 signaling pathway positive regulation of ATP biosynthetic process	04380
TC1000001894.mm.2	Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	10	-24637913	NM_008813, BC160371 NM_008813, BC160371	18605	131	nucleic acid binding catalytic activity exonuclease activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity nucleotide diphosphatase activity nucleotide diphosphatase activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding extracellular region extracellular space extracellular space plasma membrane integral component of plasma membrane generation of precursor metabolites and energy phosphate-containing compound metabolic process immune response zinc ion binding nucleoside triphosphate catabolic process nucleoside triphosphate catabolic process cell surface cell surface cell surface membrane integral component of membrane hydrolase activity polysaccharide binding negative regulation of ossification negative regulation of cell growth melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport inorganic diphosphate transport cellular phosphate ion homeostasis sequestering of triglyceride biomineral tissue development negative regulation of protein autophosphorylation cellular response to insulin stimulus NADH pyrophosphatase activity identical protein binding protein homodimerization activity cell projection neuron projection neuronal cell body cell body synapse negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process ATP metabolic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway bone remodeling metal ion binding nucleoside-triphosphate diphosphatase activity nucleoside-triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process nucleic acid phosphodiester bond hydrolysis apical dendrite basal dendrite cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity negative regulation of hh target transcription factor activity	00230 00500 00740 00760 00770 01100
TC1900000508.mm.2	Kif20b	kinesin family member 20B	19	34922357	NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148	240641	35	nucleotide binding neural tube closure microtubule motor activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytosol cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle regulation of mitotic nuclear division microtubule binding microtubule binding positive regulation of cell population proliferation positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed microtubule cytoskeleton ATPase activity ATPase activity midbody midbody positive regulation of cytokinesis protein localization to microtubule protein homodimerization activity cell projection intercellular bridge perinuclear region of cytoplasm neuron projection morphogenesis WW domain binding spindle midzone cell division regulation of establishment of protein localization contractile ring positive regulation of intracellular protein transport mitotic spindle pole positive regulation of mitotic cytokinetic process mitotic spindle midzone regulation of establishment of cell polarity regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration
TC1700001173.mm.2	Rasgrp3	RAS, guanyl releasing protein 3	17	75435904, 75465537	NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127	240168	21	guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm Ras protein signal transduction kinase binding small GTPase binding small GTPase binding guanyl-nucleotide exchange factor complex regulation of GTPase activity perinuclear region of cytoplasm	04010 04662
TC1100002001.mm.2	Slc26a11	solute carrier family 26, member 11	11	119355556	NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897	268512	17	nucleoplasm lysosome lysosomal membrane endoplasmic reticulum Golgi apparatus plasma membrane integral component of plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity sulfate transmembrane transporter activity anion:anion antiporter activity membrane integral component of membrane intracellular membrane-bounded organelle transmembrane transport
TC0400002010.mm.2	Nol9	nucleolar protein 9	4	152039320, 152039320, 152039337	NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099	74035	19	nucleotide binding cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA RNA binding ATP binding nucleus nucleolus rRNA processing RNA processing kinase activity transferase activity intermediate filament cytoskeleton polynucleotide 5'-hydroxyl-kinase activity polynucleotide 5'-hydroxyl-kinase activity
TC0100002965.mm.2	Steap3	STEAP family member 3	1	-120226413, -120226413, -120226413, -120226413	NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435	68428	33	ferric-chelate reductase activity ferric-chelate reductase activity protein binding cytoplasm endosome endosome multivesicular body plasma membrane plasma membrane ion transport iron ion transport apoptotic process cell cycle cupric reductase activity cupric reductase activity protein secretion protein secretion copper ion import copper ion import copper ion import membrane integral component of membrane oxidoreductase activity iron import into cell identical protein binding positive regulation of apoptotic process metal ion binding ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity iron ion homeostasis iron ion import across cell outer membrane iron ion import across cell outer membrane positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator exosomal secretion	04115
TC0300002500.mm.2	H3c15	H3 clustered histone 15	3	96246699, -96238478	NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965	97114	5	nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC0300003216.mm.2					NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965			negative regulation of transcription by RNA polymerase II nuclear chromosome nucleosome chromatin binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing
TC0200002990.mm.2	Hacd1	3-hydroxyacyl-CoA dehydratase 1	2	-14026830	NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017	30963	14	endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development regulation of G2/M transition of mitotic cell cycle positive regulation of cell-substrate adhesion myotube differentiation membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation cellular protein-containing complex assembly very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process hydroxyapatite binding cementum mineralization 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity regulation of G1/S transition of mitotic cell cycle
TC0700000236.mm.2	Slc1a5	solute carrier family 1 (neutral amino acid transporter), member 5	7	16781345	NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462	20514	33	plasma membrane plasma membrane amino acid transport glutamine transport basal plasma membrane glutamine secretion neutral amino acid transmembrane transporter activity L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity symporter activity L-serine transport membrane integral component of membrane metal ion binding protein homotrimerization L-aspartate import across plasma membrane L-aspartate import across plasma membrane transport across blood-brain barrier L-glutamine import across plasma membrane	04974
TC1300000972.mm.2	Mef2c	myocyte enhancer factor 2C	13	83504033, 83573606, 83524742, 83523655	NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650	17260	401	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade MAPK cascade transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development osteoblast differentiation osteoblast differentiation neuron migration B cell homeostasis heart looping endochondral ossification endochondral ossification blood vessel remodeling chondrocyte differentiation germinal center formation regulation of germinal center formation primary heart field specification secondary heart field specification outflow tract morphogenesis sinoatrial valve morphogenesis cardiac ventricle formation cardiac ventricle formation DNA binding DNA binding minor groove of adenine-thymine-rich DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II apoptotic process humoral immune response multicellular organism development nervous system development heart development heart development skeletal muscle tissue development muscle cell fate determination learning or memory positive regulation of cardiac muscle hypertrophy positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of alkaline phosphatase activity neural crest cell differentiation cardiac muscle hypertrophy in response to stress nuclear speck sarcomere cell differentiation neuron differentiation platelet formation monocyte differentiation negative regulation of ossification melanocyte differentiation positive regulation of bone mineralization positive regulation of B cell proliferation protein-containing complex activating transcription factor binding cellular response to drug skeletal muscle cell differentiation skeletal muscle cell differentiation cellular response to trichostatin A B cell proliferation histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding cell fate commitment regulation of megakaryocyte differentiation positive regulation of myoblast differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion protein heterodimerization activity protein dimerization activity regulation of synaptic plasticity positive regulation of skeletal muscle tissue development neuron development cell morphogenesis involved in neuron differentiation embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis negative regulation of epithelial cell proliferation B cell receptor signaling pathway smooth muscle cell differentiation regulation of synapse assembly regulation of synaptic transmission, glutamatergic cardiac muscle cell differentiation cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation roof of mouth development regulation of synaptic activity positive regulation of cardiac muscle cell proliferation excitatory postsynaptic potential transdifferentiation regulation of sarcomere organization cartilage morphogenesis regulation of dendritic spine development renal tubule morphogenesis cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to growth factor stimulus cellular response to parathyroid hormone stimulus cellular response to fluid shear stress cellular response to transforming growth factor beta stimulus HMG box domain binding positive regulation of cell proliferation in bone marrow glomerulus morphogenesis nephron tubule epithelial cell differentiation negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular endothelial cell proliferation sequence-specific double-stranded DNA binding positive regulation of macrophage apoptotic process regulation of NMDA receptor activity regulation of AMPA receptor activity positive regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell differentiation positive regulation of behavioral fear response epithelial cell proliferation involved in renal tubule morphogenesis positive regulation of skeletal muscle cell differentiation	04010
TC1100003470.mm.2	Prr11	proline rich 11	11	-87089155	NM_175563, BC023918 NM_175563, BC023918	270906	14	molecular_function nucleus nucleus cytoplasm cytoplasm cell cycle arrest regulation of cell cycle
TC0200002474.mm.2	Srsf6	serine and arginine-rich splicing factor 6	2	162931507	NM_026499, BC012039 NM_026499, BC012039	67996	30	alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus mRNA splice site selection mRNA splice site selection mRNA processing RNA splicing negative regulation of gene expression regulation of keratinocyte proliferation nuclear speck nuclear speck pre-mRNA binding negative regulation of keratinocyte differentiation negative regulation of mRNA splicing, via spliceosome positive regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of cell death regulation of wound healing negative regulation of type B pancreatic cell apoptotic process	03040
TC0400003390.mm.2	Cdc20	cell division cycle 20	4	-118432900	NM_023223, BC003215 NM_023223, BC003215	107995	81	mitotic metaphase protein binding nucleoplasm anaphase-promoting complex anaphase-promoting complex cytoplasm centrosome cytosol cytoskeleton cell cycle mitotic sister chromatid cohesion nervous system development protein C-terminus binding positive regulation of cell population proliferation anaphase-promoting complex binding enzyme binding cell differentiation anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of synaptic plasticity protein-containing complex regulation of meiotic nuclear division histone deacetylase binding perinuclear region of cytoplasm regulation of dendrite development cell division positive regulation of synapse maturation mitotic spindle assembly ubiquitin-protein transferase activator activity positive regulation of ubiquitin protein ligase activity positive regulation of anaphase-promoting complex-dependent catabolic process ubiquitin ligase activator activity	04110 04114 04120
TC1300000174.mm.2	H3c10	H3 clustered histone 10	13	21717627	NM_178206	319152	3	nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing	05322
TC0600001279.mm.2	Pparg	peroxisome proliferator activated receptor gamma	6	115422065, 115360950, 115362348, 115361143	NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798	19016	1453	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific negative regulation of cytokine production placenta development response to dietary excess diet induced thermogenesis negative regulation of acute inflammatory response DNA binding DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity steroid hormone receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II fatty acid metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response signal transduction protein C-terminus binding transcription factor binding regulation of blood pressure zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation response to light stimulus hormone-mediated signaling pathway regulation of gene expression macrophage derived foam cell differentiation negative regulation of macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of cholesterol storage negative regulation of sequestering of triglyceride long-chain fatty acid transport negative regulation of angiogenesis regulation of lipid metabolic process regulation of lipid metabolic process fatty acid oxidation enzyme binding protein phosphatase binding cell differentiation monocyte differentiation negative regulation of cell growth estrogen receptor binding nuclear receptor coactivator activity negative regulation of BMP signaling pathway epithelial cell differentiation response to food cellular response to insulin stimulus cellular response to insulin stimulus negative regulation of collagen biosynthetic process activating transcription factor binding response to lipid response to lipid peroxisome proliferator activated receptor signaling pathway peroxisome proliferator activated receptor signaling pathway peptide binding glucose homeostasis regulation of circadian rhythm identical protein binding lipoprotein transport positive regulation of apoptotic process intracellular membrane-bounded organelle receptor complex positive regulation of DNA binding negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding protein self-association cell fate commitment cell fate commitment fat cell differentiation fat cell differentiation fat cell differentiation fat cell differentiation regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation negative regulation of osteoblast differentiation negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fatty acid metabolic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fatty acid oxidation metal ion binding retinoid X receptor binding retinoic acid receptor signaling pathway retinoic acid receptor signaling pathway cell maturation perinuclear region of cytoplasm rhythmic process negative regulation of smooth muscle cell proliferation positive regulation of oligodendrocyte differentiation arachidonic acid binding DNA binding domain binding LBD domain binding WW domain binding negative regulation of inflammatory response white fat cell differentiation white fat cell differentiation brown fat cell differentiation positive regulation of DNA-binding transcription factor activity alpha-actinin binding negative regulation of telomerase activity positive regulation of phagocytosis, engulfment negative regulation of interferon-gamma-mediated signaling pathway negative regulation of gene silencing by miRNA E-box binding cellular response to lithium ion cellular response to low-density lipoprotein particle stimulus cellular response to organic cyclic compound negative regulation of peptide hormone secretion RNA polymerase II transcription regulator complex negative regulation of neuroinflammatory response negative regulation of cellular response to insulin stimulus positive regulation of pri-miRNA transcription by RNA polymerase II negative regulation of microglial cell activation negative regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular endothelial cell proliferation positive regulation of low-density lipoprotein receptor activity promoter-specific chromatin binding negative regulation of pancreatic stellate cell proliferation negative regulation of signaling receptor activity	03320 04380 05016 05200 05216
TC0200005164.mm.2	Sulf2	sulfatase 2	2	-166073898, -166073898	NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086	72043	66	kidney development chondrocyte development glomerular filtration catalytic activity arylsulfatase activity calcium ion binding glycosaminoglycan binding extracellular space endoplasmic reticulum endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane sulfur compound metabolic process N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity response to wounding cell surface cell surface positive regulation of vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production esophagus smooth muscle contraction hydrolase activity positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process glomerular basement membrane development glomerular basement membrane development glial cell-derived neurotrophic factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway metal ion binding embryonic skeletal system development cartilage development bone development innervation positive regulation of canonical Wnt signaling pathway liver regeneration regulation of hepatocyte proliferation
TC1900000184.mm.2	Rab3il1	RAB3A interacting protein (rabin3)-like 1	19	10018193, 10001668, 10018193, 10018193, 10018250, 10001724, 10015046, 10018250	NM_144538, BC020147 NM_144538, BC020147	74760	19	guanyl-nucleotide exchange factor activity exocytosis protein transport kinase binding identical protein binding Golgi to plasma membrane transport vesicle
TC1600000447.mm.2	Tfrc	transferrin receptor	16	32608895, 32609121	NM_011638, BC054522 NM_011638, BC054522	22042	174	positive regulation of protein phosphorylation double-stranded RNA binding transferrin receptor activity transferrin receptor activity iron ion transmembrane transporter activity protein binding extracellular region extracellular space nucleus cytoplasm mitochondrion endosome endosome early endosome plasma membrane plasma membrane integral component of plasma membrane clathrin-coated pit clathrin-coated pit iron ion transport iron ion transport cellular iron ion homeostasis cellular iron ion homeostasis endocytosis receptor-mediated endocytosis external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface endosome membrane positive regulation of gene expression negative regulation of mitochondrial fusion membrane membrane integral component of membrane basolateral plasma membrane protein kinase binding osteoclast differentiation Hsp70 protein binding positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of protein-containing complex assembly cytoplasmic vesicle receptor internalization cellular response to extracellular stimulus positive regulation of peptidyl-serine phosphorylation transferrin transport intracellular signal transduction cellular response to drug positive regulation of T cell proliferation positive regulation of T cell proliferation identical protein binding protein homodimerization activity negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling intracellular membrane-bounded organelle protein-containing complex binding positive regulation of bone resorption positive regulation of isotype switching perinuclear region of cytoplasm perinuclear region of cytoplasm chaperone binding positive regulation of NF-kappaB transcription factor activity recycling endosome recycling endosome recycling endosome membrane extracellular exosome extracellular exosome cellular response to iron ion positive regulation of protein localization to nucleus HFE-transferrin receptor complex HFE-transferrin receptor complex cellular response to leukemia inhibitory factor	04144 04145 04640
TC0400001107.mm.2	Dhcr24	24-dehydrocholesterol reductase	4	106561037	NM_053272, BC019797 NM_053272, BC019797	74754	47	delta24(24-1) sterol reductase activity delta24(24-1) sterol reductase activity nucleus cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus cytosol cytoskeleton lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process Ras protein signal transduction protein localization steroid metabolic process steroid metabolic process cholesterol metabolic process negative regulation of cell population proliferation tissue development tissue development membrane membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor enzyme binding male genitalia development plasminogen activation peptide antigen binding amyloid precursor protein catabolic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process skin development delta24-sterol reductase activity flavin adenine dinucleotide binding membrane organization FAD binding	00100 01100
TC1400000975.mm.2	Entpd4	ectonucleoside triphosphate diphosphohydrolase 4	14	69337150, 69555400	BC043134, NM_026174 BC043134, NM_026174	67464	23	Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane	00230 00240 04142
TC0200003195.mm.2	Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	2	-26593056	NM_026212, BC125530, BC137840 NM_026212, BC125530, BC137840 NM_026212, BC125530, BC137840	67512	31	positive regulation of cytokine production 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lipid metabolic process phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process phospholipid biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring acyl groups	00561 00564 01100 04975
TC1300000543.mm.2	Rnf144b	ring finger protein 144B	13	47194002, 47122719	NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007	218215	20	ubiquitin ligase complex protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoplasm mitochondrion ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process apoptotic process membrane integral component of membrane protein ubiquitination transferase activity ubiquitin conjugating enzyme binding mitochondrial membrane mitochondrial membrane positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of apoptotic process metal ion binding ubiquitin protein ligase activity
TC0300002334.mm.2	Fdps	farnesyl diphosphate synthetase	3	-89093587	NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886	110196	37	dimethylallyltranstransferase activity geranyltranstransferase activity geranyltranstransferase activity nucleoplasm cytoplasm mitochondrion mitochondrial matrix peroxisome cytosol lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process sterol biosynthetic process transferase activity farnesyl diphosphate biosynthetic process farnesyl diphosphate biosynthetic process positive regulation of cholesterol biosynthetic process metal ion binding positive regulation of cell growth involved in cardiac muscle cell development	00900 01100
TC0100002866.mm.2	Pam	peptidylglycine alpha-amidating monooxygenase	1	-97821093, -97821093	NM_013626, BC166013 NM_013626, BC166013	18484	51	peptide amidation long-chain fatty acid metabolic process catalytic activity monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding calcium ion binding extracellular region extracellular space trans-Golgi network cytosol plasma membrane integral component of plasma membrane regulation of transcription by RNA polymerase II peptide metabolic process peptide metabolic process metabolic process zinc ion binding response to pH toxin metabolic process cell surface response to zinc ion membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen lyase activity protein amidation protein metabolic process protein kinase binding secretory granule secretory granule membrane cytoplasmic vesicle L-ascorbic acid binding regulation of actin cytoskeleton organization response to drug identical protein binding neuron projection neuronal cell body perikaryon metal ion binding perinuclear region of cytoplasm regulation of protein secretion fatty acid primary amide biosynthetic process
TC1500001656.mm.2	Sla	src-like adaptor	15	-66780818	NM_001029841, NM_009192, BC032922 NM_001029841, NM_009192, BC032922 NM_001029841, NM_009192, BC032922	20491	49	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding cytoplasm endosome focal adhesion transmembrane receptor protein tyrosine kinase signaling pathway regulation of signal transduction cell differentiation extrinsic component of cytoplasmic side of plasma membrane dendritic spine innate immune response
TC0900002369.mm.2	Scamp5	secretory carrier membrane protein 5	9	-57441326	NM_020270, BC018613 NM_020270, BC018613	56807	22	Golgi membrane positive regulation of cytokine production endosome Golgi apparatus plasma membrane exocytosis synaptic vesicle synaptic vesicle protein transport membrane integral component of membrane cell junction integral component of synaptic vesicle membrane cytoplasmic vesicle trans-Golgi network membrane trans-Golgi network membrane response to endoplasmic reticulum stress protein-containing complex binding synapse negative regulation of endocytosis positive regulation of calcium ion-dependent exocytosis recycling endosome membrane recycling endosome membrane regulation of synaptic vesicle endocytosis
TC0200004811.mm.2	Cd93	CD93 antigen	2	-148436650	NM_010740, BC156937, CD93 NM_010740, BC156937, CD93 NM_010740, BC156937, CD93	17064	42	complement component C1q complex binding calcium ion binding plasma membrane plasma membrane cell adhesion cell surface membrane integral component of membrane carbohydrate binding cytoplasmic vesicle cell-cell adhesion cell-cell adhesion
TC1300001576.mm.2					NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373			DNA binding nucleus chromatin silencing negative regulation of cell population proliferation
TC1800000528.mm.2	Sncaip	synuclein, alpha interacting protein (synphilin)	18	52768092, 52767810, 52768143	NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489	67847	40	nucleoplasm cytoplasm cell death ubiquitin protein ligase binding cytoplasmic ribonucleoprotein granule dopamine metabolic process identical protein binding regulation of neurotransmitter secretion regulation of inclusion body assembly	05012
TC1400000075.mm.2	Rpp14	ribonuclease P 14 subunit	14	8080312	NM_025938, BC026988, BC046803 NM_025938, BC026988, BC046803 NM_025938, BC026988, BC046803	67053	20	tRNA 5'-leader removal ribonuclease P activity nucleolus multimeric ribonuclease P complex ribonuclease P RNA binding	03013
TC0800002235.mm.2	Neil3	nei like 3 (E. coli)	8	-53586866	NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753	234258	34	bubble DNA binding nucleic acid binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding catalytic activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity nucleus nucleus nucleoplasm chromosome DNA repair base-excision repair base-excision repair base-excision repair nucleotide-excision repair cellular response to DNA damage stimulus metabolic process zinc ion binding hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds lyase activity DNA N-glycosylase activity DNA N-glycosylase activity DNA N-glycosylase activity metal ion binding	03410
TC0500000054.mm.2	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	5	8893720	NM_008830, BC150687 NM_008830, BC150687	18670	156	Golgi membrane nucleotide binding ATP binding nucleoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane plasma membrane focal adhesion lipid transport actin cytoskeleton membrane integral component of membrane apical plasma membrane ATPase activity cytoplasmic vesicle positive regulation of cholesterol transport bile acid secretion ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity phospholipid translocation phospholipid translocation intercellular canaliculus transmembrane transport lipid homeostasis positive regulation of phospholipid translocation phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity ceramide floppase activity response to fenofibrate cellular response to bile acid positive regulation of phospholipid transport	02010 04976
TC1700000775.mm.2	Olfr110	olfactory receptor 110	17	37492467	NM_146328, BC132347 NM_146328, BC132347	258325	7	olfactory receptor activity G protein-coupled receptor signaling pathway sensory perception of smell integral component of membrane	04740
TC0400003000.mm.2	Hacd4	3-hydroxyacyl-CoA dehydratase 4	4	-88413955, -88410341	NM_025760, BC020155 NM_025760, BC020155	66775	13	endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity
TC1200002396.mm.2	Cinp	cyclin-dependent kinase 2 interacting protein	12	-110872609	NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867	67236	17	molecular_function cellular_component nucleus DNA replication DNA repair cellular response to DNA damage stimulus cell cycle biological_process cell division
TC0700000652.mm.2	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	7	35119292, 35119292	NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161	12606	476	urea cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase I transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development embryonic placenta development DNA binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex nucleolus regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase I mitochondrion organization Notch signaling pathway multicellular organism development transcription factor binding transcription factor binding cholesterol metabolic process negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix cytokine-mediated signaling pathway kinase binding kinase binding protein domain specific binding myeloid cell differentiation myeloid cell differentiation macrophage differentiation lung development granulocyte differentiation granulocyte differentiation protein-containing complex Rb-E2F complex CHOP-C/EBP complex regulation of cell population proliferation glucose homeostasis identical protein binding protein homodimerization activity histone deacetylase binding positive regulation of macrophage activation intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding protein-containing complex binding fat cell differentiation fat cell differentiation fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation negative regulation of cell cycle negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III protein heterodimerization activity cell maturation inner ear development positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation lipid homeostasis interleukin-6-mediated signaling pathway cellular response to lithium ion cellular response to tumor necrosis factor cellular response to organic cyclic compound HMG box domain binding RNA polymerase II transcription regulator complex positive regulation of DNA-templated transcription, initiation	05200 05221
TC1500002012.mm.2	Cerk	ceramide kinase	15	-86139100	NM_145475, BC094253 NM_145475, BC094253	223753	42	nucleotide binding magnesium ion binding lipid kinase activity ceramide kinase activity ceramide kinase activity ceramide kinase activity ceramide kinase activity NAD+ kinase activity ATP binding cytoplasm mitochondrion plasma membrane sphingolipid metabolic process ceramide metabolic process ceramide metabolic process membrane integral component of membrane kinase activity phosphorylation transferase activity	00600
TC1900000727.mm.2	Gsto1	glutathione S-transferase omega 1	19	47854972	NM_010362, BC085165 NM_010362, BC085165	14873	36	glutathione transferase activity basement membrane nucleoplasm cytoplasm cytosol regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum oxidoreductase activity transferase activity L-ascorbic acid metabolic process L-ascorbic acid biosynthetic process axon nuclear membrane xenobiotic catabolic process myelin sheath cell body glutathione dehydrogenase (ascorbate) activity glutathione dehydrogenase (ascorbate) activity methylarsonate reductase activity negative regulation of ryanodine-sensitive calcium-release channel activity positive regulation of ryanodine-sensitive calcium-release channel activity cellular response to arsenic-containing substance	00480 00980 00982
TC0400002980.mm.2	Plin2	perilipin 2	4	-86656564	NM_007408, BC054766 NM_007408, BC054766	11520	135	protein binding nucleus cytoplasm lipid droplet lipid droplet lipid droplet cytosol cytosol plasma membrane positive regulation of sequestering of triglyceride long-chain fatty acid transport membrane lipid storage lipid storage
TC0200001760.mm.2	Rad51	RAD51 recombinase	2	119112813	NM_011234, BC027384 NM_011234, BC027384	19361	173	recombinase activity nucleotide binding nuclear chromosome telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA recombinase assembly DNA recombinase assembly chromosome, telomeric region chromosome, telomeric region chromatin condensed chromosome condensed nuclear chromosome condensed nuclear chromosome synaptonemal complex lateral element lateral element regulation of protein phosphorylation DNA binding chromatin binding chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytoplasm mitochondrion cytoskeleton DNA metabolic process DNA unwinding involved in DNA replication DNA repair DNA recombination mitotic recombination cellular response to DNA damage stimulus cellular response to DNA damage stimulus reciprocal meiotic recombination reciprocal meiotic recombination protein C-terminus binding DNA-dependent ATPase activity regulation of double-strand break repair via homologous recombination telomere maintenance via telomere lengthening PML body single-stranded DNA helicase activity enzyme binding replication fork processing replication fork processing telomere organization protein-containing complex site of double-strand break interstrand cross-link repair strand invasion identical protein binding perinuclear region of cytoplasm positive regulation of DNA ligation meiotic cell cycle DNA polymerase binding chromosome organization involved in meiotic cell cycle chromosome organization involved in meiotic cell cycle cellular response to alkaloid cellular response to ionizing radiation cellular response to hydroxyurea cellular response to camptothecin replication-born double-strand break repair via sister chromatid exchange mitotic recombination-dependent replication fork processing	03440 05200 05212
TC1600001373.mm.2	Tmem41a	transmembrane protein 41a	16	-21934326	NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770	66664	13	molecular_function cellular_component biological_process membrane integral component of membrane
TC0500002152.mm.2	Tyms	thymidylate synthase	5	-30058199	NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139	22171	38	translation repressor activity, mRNA regulatory element binding mRNA binding thymidylate synthase activity thymidylate synthase activity folic acid binding nucleus nucleolus cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix cytosol dTMP biosynthetic process dTMP biosynthetic process regulation of translation methyltransferase activity nucleotide biosynthetic process membrane transferase activity negative regulation of translation methylation tetrahydrofolate interconversion protein homodimerization activity heterocyclic compound binding sequence-specific mRNA binding	00240 00670 01100
TC0600001400.mm.2	Clec4b1	C-type lectin domain family 4, member b1	6	123049961	NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521	69810	15	positive regulation of release of sequestered calcium ion into cytosol
TC1600001143.mm.2	Ubald1	UBA-like domain containing 1	16	-4874778	NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081	207740	15	molecular_function cellular_component biological_process
TC1700001003.mm.2	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	17	56303336, 56304312	NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167	18140	107	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin euchromatin heterochromatin heterochromatin cis-regulatory region sequence-specific DNA binding DNA binding ubiquitin-protein transferase activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork replication fork plasma membrane DNA repair chromatin organization ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus cell cycle zinc ion binding methyl-CpG binding maintenance of DNA methylation maintenance of DNA methylation maintenance of DNA methylation histone monoubiquitination histone monoubiquitination nuclear matrix protein ubiquitination histone ubiquitination transferase activity cytoplasmic vesicle nucleosomal histone binding positive regulation of cellular protein metabolic process methylated histone binding methylated histone binding histone binding identical protein binding hemi-methylated DNA-binding hemi-methylated DNA-binding metal ion binding regulation of epithelial cell proliferation protein autoubiquitination protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity
TC0200002542.mm.2	Mmp9	matrix metallopeptidase 9	2	164948218	NM_013599, BC046991 NM_013599, BC046991	17395	1041	skeletal system development skeletal system development positive regulation of protein phosphorylation fibronectin binding positive regulation of leukocyte migration endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity extracellular region extracellular space proteolysis response to oxidative stress heart development embryo implantation aging peptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity transformation of host cell by virus extracellular matrix organization extracellular matrix organization extracellular matrix organization positive regulation of cell migration collagen catabolic process collagen catabolic process collagen catabolic process extracellular matrix positive regulation of synaptic plasticity protein-containing complex cellular response to reactive oxygen species response to drug identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding protein-containing complex binding positive regulation of epidermal growth factor receptor signaling pathway positive regulation of angiogenesis metal ion binding negative regulation of fibroblast proliferation tissue remodeling positive regulation of keratinocyte migration collagen-containing extracellular matrix cellular response to cadmium ion cellular response to cell-matrix adhesion cellular response to UV-A positive regulation of release of cytochrome c from mitochondria positive regulation of receptor binding response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of epithelial cell differentiation involved in kidney development negative regulation of intrinsic apoptotic signaling pathway negative regulation of cation channel activity negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	04670 05200 05219
TC1100004183.mm.2	Sgsh	N-sulfoglucosamine sulfohydrolase (sulfamidase)	11	-119343488	NM_018822, BC130268 NM_018822, BC130268	27029	46	protein binding glycosaminoglycan binding lysosome lysosome glycosaminoglycan catabolic process glycosaminoglycan catabolic process N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity sulfuric ester hydrolase activity N-sulfoglucosamine sulfohydrolase activity N-sulfoglucosamine sulfohydrolase activity heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan metabolic process	00531 01100 04142
TC1600001262.mm.2	Fgd4	FYVE, RhoGEF and PH domain containing 4	16	-16416914, -16416914, -16416914	NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234	224014	30	actin binding guanyl-nucleotide exchange factor activity cytoplasm cytoskeleton cytoskeleton organization activation of JUN kinase activity regulation of cell shape lamellipodium lamellipodium assembly microspike assembly filopodium regulation of Rho protein signal transduction cell projection filopodium assembly metal ion binding actin filament binding
TC0700002617.mm.2	Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	7	-24978168, -24978168	BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921	232975	83	nucleotide binding amyloid-beta binding photoreceptor inner segment P-type sodium:potassium-exchanging ATPase activity P-type sodium:potassium-exchanging ATPase activity ATP binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex ion transport potassium ion transport sodium ion transport cellular sodium ion homeostasis cellular sodium ion homeostasis cellular sodium ion homeostasis memory adult locomotory behavior visual learning potassium transmembrane transporter activity, phosphorylative mechanism membrane integral component of membrane cellular potassium ion homeostasis cellular potassium ion homeostasis axon organelle membrane D1 dopamine receptor binding ionotropic glutamate receptor signaling pathway sodium ion export across plasma membrane sodium ion export across plasma membrane sodium ion export across plasma membrane sarcolemma response to drug neuronal cell body myelin sheath myelin sheath heparan sulfate proteoglycan binding calyx of Held dendritic spine neck dendritic spine head synapse metal ion binding chaperone binding cardiac muscle contraction regulation of cardiac muscle cell membrane potential sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential postsynapse neuron to neuron synapse integral component of presynaptic membrane ion antiporter activity involved in regulation of presynaptic membrane potential proton transmembrane transport cellular response to amyloid-beta neuron projection maintenance potassium ion import across plasma membrane potassium ion import across plasma membrane	04260 04960 04964 04970 04971 04972 04973 04974 04976
TC0300000491.mm.2	P2ry1	purinergic receptor P2Y, G-protein coupled 1	3	61002784	NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635	18441	114	nucleotide binding G protein-coupled ADP receptor activity positive regulation of protein phosphorylation G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor activity ATP binding mitochondrion plasma membrane plasma membrane integral component of plasma membrane cilium signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration glial cell migration regulation of cell shape response to mechanical stimulus regulation of signaling receptor activity negative regulation of norepinephrine secretion postsynaptic density membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain signal transduction involved in regulation of gene expression platelet activation dendrite A1 adenosine receptor binding positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway eating behavior positive regulation of ion transport positive regulation of ion transport ADP binding cell body G protein-coupled purinergic nucleotide receptor activity G protein-coupled ATP receptor activity postsynaptic membrane positive regulation of transcription by RNA polymerase II positive regulation of hormone secretion protein heterodimerization activity negative regulation of binding positive regulation of penile erection positive regulation of ERK1 and ERK2 cascade cellular response to organic cyclic compound cellular response to purine-containing compound protein localization to plasma membrane relaxation of muscle scaffold protein binding blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis	04080
TC1300000245.mm.2	H2ac10	H2A clustered histone 10	13	23533874	NM_175661, BC125011 NM_175661, BC125011	319173	10	nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity	05322
TC1000002341.mm.2	Cdk1	cyclin-dependent kinase 1	10	-69335145	NM_007659, BC024396 NM_007659, BC024396	12534	223	G2/M transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix centrosome cytosol cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint cell aging cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity response to organonitrogen compound positive regulation of gene expression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation chromosome condensation cyclin binding midbody Hsp70 protein binding animal organ regeneration protein localization to kinetochore histone kinase activity positive regulation of protein import into nucleus regulation of circadian rhythm negative regulation of apoptotic process mitotic cell cycle phase transition response to ethanol positive regulation of DNA replication positive regulation of mitotic cell cycle rhythmic process cell division positive regulation of cardiac muscle cell proliferation protein-containing complex assembly mitotic spindle Golgi disassembly cyclin B1-CDK1 complex cyclin-dependent protein kinase activity positive regulation of protein localization to nucleus positive regulation of mitochondrial ATP synthesis coupled electron transport	04110 04114 04115 04540 04914
TC0500001663.mm.2	Fam20c	FAM20C, golgi associated secretory pathway kinase	5	138755080	NM_030565	80752	44	nucleotide binding skeletal system development protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity calcium ion binding ATP binding extracellular region extracellular space extracellular space extracellular space cytoplasm cytoplasm Golgi apparatus Golgi apparatus protein phosphorylation protein phosphorylation protein phosphorylation kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor manganese ion binding positive regulation of bone mineralization biomineral tissue development osteoclast maturation regulation of fibroblast growth factor receptor signaling pathway positive regulation of osteoblast differentiation ATP metabolic process metal ion binding regulation of phosphorus metabolic process enamel mineralization enamel mineralization odontoblast differentiation dentinogenesis
TC1500000432.mm.2	Sqle	squalene epoxidase	15	59315091	NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361	20775	31	squalene monooxygenase activity squalene monooxygenase activity endoplasmic reticulum cellular aromatic compound metabolic process cholesterol metabolic process cholesterol metabolic process response to organic substance membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process oxidoreductase activity regulation of cell population proliferation intracellular membrane-bounded organelle flavin adenine dinucleotide binding FAD binding lipid droplet formation	00100 01100
TC1600001191.mm.2	Emp2	epithelial membrane protein 2	16	-10281748	NM_007929, BC041670 NM_007929, BC041670	13731	31	membrane raft assembly T cell mediated cytotoxicity regulation of cell-matrix adhesion regulation of cell-matrix adhesion positive regulation of cell-matrix adhesion regulation of glomerular filtration integrin binding integrin binding nucleus cytoplasm cytoplasm cytoplasm Golgi apparatus plasma membrane plasma membrane actin filament organization cell adhesion cell adhesion cell-matrix adhesion embryo implantation embryo implantation cell death positive regulation of cell population proliferation cell surface regulation of endothelial cell migration membrane integral component of membrane apical plasma membrane cell migration kinase binding protein kinase binding protein kinase binding cytoplasmic vesicle bleb assembly activation of protein kinase activity protein localization to cell surface blood vessel endothelial cell migration regulation of kinase activity early endosome to late endosome transport membrane raft membrane raft apical part of cell regulation of angiogenesis actin-mediated cell contraction protein localization to plasma membrane positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway regulation of vasculogenesis
TC0900002503.mm.2	Hacd3	3-hydroxyacyl-CoA dehydratase 3	9	-64986982	NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023	57874	26	protein binding endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process I-kappaB kinase/NF-kappaB signaling JNK cascade Rho protein signal transduction membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation nuclear membrane very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process positive regulation of viral genome replication positive regulation by virus of viral protein levels in host cell 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity
TC1300000572.mm.2	Iars	isoleucine-tRNA synthetase	13	49682129	NM_172015, BC067029 NM_172015, BC067029	105148	26	tRNA binding nucleotide binding aminoacyl-tRNA editing activity aminoacyl-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity ATP binding nucleoplasm cytoplasm cytosol translation tRNA aminoacylation for protein translation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex GTPase binding	00290 00970
TC1000002264.mm.2	Ddx21	DExD box helicase 21	10	-62580246	NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237	56200	47	nucleotide binding immune system process positive regulation of myeloid dendritic cell cytokine production nucleic acid binding RNA binding RNA binding RNA helicase activity RNA helicase activity RNA helicase activity double-stranded RNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus cytoplasm mitochondrion cytosol rRNA processing transcription by RNA polymerase II response to virus hydrolase activity rRNA binding snoRNA binding miRNA binding identical protein binding positive regulation of I-kappaB kinase/NF-kappaB signaling response to exogenous dsRNA innate immune response defense response to virus R-loop disassembly 7SK snRNA binding
TC0800000959.mm.2	Lyl1	lymphoblastomic leukemia 1	8	84701456	NM_008535, BC005736 NM_008535, BC005736	17095	45	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific blood vessel maturation DNA binding nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II B cell differentiation positive regulation of transcription, DNA-templated protein dimerization activity definitive hemopoiesis
TC1700000036.mm.2	Zdhhc14	zinc finger, DHHC domain containing 14	17	5492599	NM_146073, BC059814 NM_146073, BC059814	224454	19	endoplasmic reticulum endoplasmic reticulum Golgi apparatus protein targeting to membrane membrane integral component of membrane palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity
TC0200004410.mm.2	Gpr176	G protein-coupled receptor 176	2	-118277097	NM_201367, BC052037 NM_201367, BC052037	381413	18	G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway membrane integral component of membrane rhythmic process circadian behavior
TC1100000582.mm.2	Cdkn2aipnl	CDKN2A interacting protein N-terminal like	11	51967630	NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363	52626	20	molecular_function nucleoplasm nucleolus
TC1800001048.mm.2	B4galt6	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6	18	-20684598	NM_019737, BC011149 NM_019737, BC011149	56386	28	lactosylceramide biosynthetic process cellular_component Golgi apparatus Golgi apparatus carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process glycosphingolipid biosynthetic process glycosphingolipid biosynthetic process galactosyltransferase activity galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity ganglioside biosynthetic process via lactosylceramide membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups central nervous system neuron axonogenesis central nervous system myelination sphingolipid biosynthetic process neuron maturation metal ion binding glycosylation	00600 01100
TC1100000983.mm.2	Pimreg	PICALM interacting mitotic regulator	11	72042501	NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115	109212	18	molecular_function nucleus nucleoplasm nucleolus cell cycle cell division
TC1600000480.mm.2	Itgb5	integrin beta 5	16	33829664	NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246	16419	91	signaling receptor binding integrin binding integrin binding protein binding plasma membrane focal adhesion focal adhesion cell adhesion cell-matrix adhesion cell-matrix adhesion transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin complex cell surface cell surface membrane integral component of membrane cell migration cell leading edge cell adhesion mediated by integrin integrin alphav-beta5 complex integrin alphav-beta5 complex signaling receptor activity stress fiber assembly stress fiber assembly receptor complex epithelial cell-cell adhesion glutamatergic synapse integral component of synaptic membrane	04145 04510 04512 04810 05410 05412 05414
TC1800001404.mm.2	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	18	-60684493, -60684493, -60684493, -60701433, -60684493, -60684493	NM_008306, BC066098, BC079561 NM_008306, BC066098, BC079561 NM_008306, BC066098, BC079561	15531	88	polysaccharide biosynthetic process cardiac septum development catalytic activity protein binding Golgi apparatus protein deacetylation protein sulfation protein sulfation inflammatory response heart development respiratory gaseous exchange by respiratory system sulfotransferase activity metabolic process cell population proliferation fibroblast growth factor receptor signaling pathway embryo development animal organ morphogenesis heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [heparan sulfate]-glucosamine N-sulfotransferase activity [heparan sulfate]-glucosamine N-sulfotransferase activity [heparan sulfate]-glucosamine N-sulfotransferase activity membrane integral component of membrane transferase activity hydrolase activity deacetylase activity deacetylase activity glycosaminoglycan metabolic process forebrain development forebrain development midbrain development aorta development positive regulation of MAPK cascade positive regulation of smoothened signaling pathway embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis coronary vasculature development heparan sulfate N-deacetylase activity	00534 01100
TC0200001776.mm.2	Nusap1	nucleolar and spindle associated protein 1	2	119618297	NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392	108907	31	mitotic sister chromatid segregation microtubule cytoskeleton organization mitotic cytokinesis mitotic cytokinesis DNA binding nucleus chromosome nucleolus nucleolus cytoplasm spindle cytoskeleton microtubule cell cycle mitotic chromosome condensation mitotic chromosome condensation microtubule binding microtubule binding establishment of mitotic spindle localization establishment of mitotic spindle localization positive regulation of mitotic nuclear division cell division mitotic spindle
TC0400001217.mm.2	Pdzk1ip1	PDZK1 interacting protein 1	4	115088707	NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542	67182	24	molecular_function biological_process membrane integral component of membrane
TC1100001155.mm.2	Spag5	sperm associated antigen 5	11	78301590	NM_017407, BC052672 NM_017407, BC052672	54141	31	mitotic sister chromatid segregation chromosome, centromeric region kinetochore chromosome cytoplasm spindle cytosol cytoskeleton microtubule cell cycle spindle organization chromosome segregation microtubule binding nuclear body positive regulation of intracellular transport centriolar satellite microtubule plus-end establishment of spindle orientation cell division regulation of attachment of spindle microtubules to kinetochore protein localization to centrosome mitotic spindle mitotic spindle regulation of metaphase plate congression mitotic spindle pole positive regulation of spindle assembly
TC0200001144.mm.2	Gm14461	predicted gene 14461	2	78237546	NM_177843	329436	10
TC0700001756.mm.2	Prkcb	protein kinase C, beta	7	122289124	NM_008855, BC127083 NM_008855, BC127083	18751	222	nucleotide binding response to hypoxia adaptive immune response immune system process chromatin binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein kinase C activity protein kinase C activity protein kinase C binding calcium channel regulator activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm centrosome cytosol plasma membrane chromatin organization regulation of transcription by RNA polymerase II protein phosphorylation calcium ion transport cellular calcium ion homeostasis apoptotic process spectrin zinc ion binding regulation of glucose transmembrane transport negative regulation of glucose transmembrane transport regulation of dopamine secretion membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation nuclear receptor coactivator activity positive regulation of vascular endothelial growth factor receptor signaling pathway brush border membrane histone kinase activity (H3-T6 specific) histone H3-T6 phosphorylation intracellular signal transduction regulation of growth B cell activation histone binding response to drug positive regulation of I-kappaB kinase/NF-kappaB signaling calyx of Held calyx of Held positive regulation of angiogenesis negative regulation of insulin receptor signaling pathway metal ion binding androgen receptor binding B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity cellular response to carbohydrate stimulus presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission presynaptic cytosol regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis	04010 04012 04020 04062 04070 04270 04310 04370 04510 04530 04540 04650 04662 04664 04666 04670 04720 04730 04912 04916 04960 04970 04971 04972 04973 05140 05143 05146 05200 05214 05223
TC0X00003021.mm.2	Tceal8	transcription elongation factor A (SII)-like 8	X	-136168983	NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269	66684	18	nucleus WW domain binding
TC0100002736.mm.2	Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	1	-86099036	NM_008311, BC023690 NM_008311, BC023690	15559	104	Gq/11-coupled serotonin receptor activity neural crest cell migration positive regulation of cytokine production positive regulation of cytokine production positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation G-protein alpha-subunit binding G protein-coupled receptor internalization heart morphogenesis cardiac muscle hypertrophy G protein-coupled receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity GTPase activator activity nucleoplasm cytoplasm cytoplasm plasma membrane plasma membrane integral component of plasma membrane cellular calcium ion homeostasis smooth muscle contraction signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger phospholipase C-activating G protein-coupled receptor signaling pathway activation of phospholipase C activity protein kinase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating serotonin receptor signaling pathway phospholipase C-activating serotonin receptor signaling pathway chemical synaptic transmission heart development behavior positive regulation of cell population proliferation negative regulation of autophagy positive regulation of phosphatidylinositol biosynthetic process neural crest cell differentiation phosphatidylinositol 3-kinase signaling intestine smooth muscle contraction membrane integral component of membrane phosphorylation calcium-mediated signaling cGMP-mediated signaling cell junction dendrite dendrite neurotransmitter receptor activity ion transmembrane transport vasoconstriction response to drug response to drug neuron projection neuronal cell body negative regulation of apoptotic process positive regulation of MAP kinase activity synapse embryonic morphogenesis regulation of behavior regulation of behavior positive regulation of nitric-oxide synthase activity release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol serotonin binding serotonin binding positive regulation of cell division negative regulation of cell death ERK1 and ERK2 cascade ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade protein kinase C signaling cellular response to amine stimulus cellular response to temperature stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled serotonin receptor complex G protein-coupled serotonin receptor complex cellular response to serotonin	04020 04080 04540
TC0400002275.mm.2	Atp6v0d2	ATPase, H+ transporting, lysosomal V0 subunit D2	4	-19876837	NM_175406, BC087899 NM_175406, BC087899	242341	45	lysosomal membrane endosome early endosome early endosome ion transport vacuolar transport vacuolar acidification proton transmembrane transporter activity membrane apical plasma membrane vacuolar proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V0 domain plasma membrane proton-transporting V-type ATPase complex proton-transporting ATPase activity, rotational mechanism proton transmembrane transport	00190 01100 04142 04145 04966 05323
TC1700001969.mm.2	Tcf19	transcription factor 19	17	-35512734	NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617	106795	29	G1/S transition of mitotic cell cycle nucleus nucleus regulation of gene expression regulation of gene expression type B pancreatic cell proliferation
TC1400000350.mm.2	Tmem273	transmembrane protein 273	14	32785962	NM_001163616	69069	8	molecular_function cellular_component biological_process
TC0400001312.mm.2					NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876			nucleus chromosome nucleolus nucleolus rRNA processing preribosome, large subunit precursor nuclear periphery ribosome biogenesis ribosomal large subunit biogenesis
TC1900001240.mm.2	Anxa1	annexin A1	19	-20373433	NM_010730, BC002289, BC004594 NM_010730, BC002289, BC004594 NM_010730, BC002289, BC004594	16952	210	cornified envelope neutrophil homeostasis neutrophil homeostasis adaptive immune response immune system process monocyte chemotaxis regulation of leukocyte migration regulation of leukocyte migration single-stranded DNA binding single-stranded RNA binding phospholipase inhibitor activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding extracellular region extracellular space extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm endosome cytosol cytosol actin filament plasma membrane plasma membrane plasma membrane cilium phagocytosis inflammatory response inflammatory response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of cell shape regulation of cell shape cell surface response to X-ray myoblast migration involved in skeletal muscle regeneration myoblast migration involved in skeletal muscle regeneration membrane apical plasma membrane lateral plasma membrane peptide cross-linking phospholipase A2 inhibitor activity phospholipase A2 inhibitor activity extrinsic component of membrane insulin secretion insulin secretion keratinocyte differentiation keratinocyte differentiation prostate gland development endocrine pancreas development extrinsic component of external side of plasma membrane positive regulation of vesicle fusion positive regulation of vesicle fusion positive regulation of prostaglandin biosynthetic process positive regulation of prostaglandin biosynthetic process cytoplasmic vesicle motile cilium actin cytoskeleton reorganization actin cytoskeleton reorganization mitochondrial membrane response to estradiol DNA duplex unwinding DNA duplex unwinding regulation of interleukin-1 production regulation of interleukin-1 production negative regulation of interleukin-8 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production protein-containing complex positive regulation of neutrophil apoptotic process positive regulation of neutrophil apoptotic process cellular response to vascular endothelial growth factor stimulus cellular response to vascular endothelial growth factor stimulus double-stranded DNA helicase activity gliogenesis positive regulation of T cell proliferation positive regulation of T cell proliferation regulation of cell population proliferation sarcolemma response to drug mast cell granule identical protein binding cell projection positive regulation of apoptotic process response to peptide hormone estrous cycle innate immune response positive regulation of T-helper 1 cell differentiation positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis negative regulation of exocytosis alpha-beta T cell differentiation alpha-beta T cell differentiation metal ion binding regulation of hormone secretion regulation of hormone secretion calcium-dependent protein binding arachidonic acid secretion arachidonic acid secretion negative regulation of protein secretion regulation of inflammatory response regulation of inflammatory response collagen-containing extracellular matrix extracellular exosome cellular response to hydrogen peroxide cellular response to hydrogen peroxide hepatocyte differentiation prolactin secretion prolactin secretion response to interleukin-1 cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus granulocyte chemotaxis granulocyte chemotaxis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of wound healing positive regulation of wound healing synaptic membrane neutrophil clearance neutrophil clearance positive regulation of G1/S transition of mitotic cell cycle positive regulation of G1/S transition of mitotic cell cycle negative regulation of phospholipase A2 activity negative regulation of phospholipase A2 activity DNA/DNA annealing activity
TC0600001397.mm.2	Clec4a1	C-type lectin domain family 4, member a1	6	122921847	NM_199311, BC049354 NM_199311, BC049354	269799	5	molecular_function cellular_component biological_process
TC1600001379.mm.2	Etv5	ets variant 5	16	-22381312, -22381312	NM_023794, BC034680 NM_023794, BC034680	104156	283	negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II neuromuscular synaptic transmission locomotory behavior cell differentiation cellular response to oxidative stress sequence-specific DNA binding positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II male germ-line stem cell asymmetric division regulation of synapse organization positive regulation of glial cell proliferation regulation of branching involved in mammary gland duct morphogenesis skeletal muscle acetylcholine-gated channel clustering sequence-specific double-stranded DNA binding
TC0100000590.mm.2	Atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	1	71557155	NM_026195, BC039925 NM_026195, BC039925	108147	24	catalytic activity IMP cyclohydrolase activity IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity mitochondrion cytosol cytosol plasma membrane purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process 'de novo' IMP biosynthetic process metabolic process nucleoside metabolic process ribonucleotide metabolic process transferase activity hydrolase activity protein homodimerization activity dihydrofolate metabolic process tetrahydrofolate biosynthetic process cellular response to interleukin-7	00230 00670 01100
TC1300001562.mm.2	H2ac22	H2A clustered histone 22	13	-21786773	NM_178184	319170	4	DNA binding nucleus chromatin silencing enzyme binding	05322
TC0300002718.mm.2	Csf1	colony stimulating factor 1 (macrophage)	3	-107745594, -107741047	NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205	12977	508	ossification positive regulation of cell-matrix adhesion osteoclast proliferation immune system process response to ischemia developmental process involved in reproduction cytokine activity cytokine activity macrophage colony-stimulating factor receptor binding protein binding extracellular region extracellular space extracellular space extracellular space plasma membrane inflammatory response transmembrane receptor protein tyrosine kinase signaling pathway growth factor activity cell population proliferation positive regulation of cell population proliferation positive regulation of gene expression positive regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of macrophage chemotaxis membrane integral component of membrane nuclear body macrophage differentiation regulation of ossification osteoclast differentiation osteoclast differentiation osteoclast differentiation positive regulation of cell migration positive regulation of cellular protein metabolic process positive regulation of mononuclear cell proliferation macrophage colony-stimulating factor signaling pathway positive regulation of multicellular organism growth odontogenesis positive regulation of odontogenesis of dentin-containing tooth identical protein binding identical protein binding protein homodimerization activity protein homodimerization activity innate immune response positive regulation of macrophage differentiation positive regulation of macrophage differentiation positive regulation of macrophage differentiation positive regulation of monocyte differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of protein kinase activity positive regulation of Ras protein signal transduction perinuclear region of cytoplasm homeostasis of number of cells within a tissue branching involved in mammary gland duct morphogenesis mammary gland fat development mammary duct terminal end bud growth microglial cell proliferation negative regulation of neuron death positive regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell migration CSF1-CSF1R complex	04060 04380 04640 05323
TC0600001474.mm.2	D6Wsu163e	DNA segment, Chr 6, Wayne State University 163, expressed	6	126939965	NM_138594, BC016429 NM_138594, BC016429	28040	17	molecular_function cytoplasm cytoplasm regulation of mast cell degranulation regulation of mast cell degranulation
TC0500000888.mm.2	Septin11	septin 11	5	93093415, 93093415	NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466	52398	38	nucleotide binding stress fiber GTPase activity protein binding GTP binding cytoplasm cytoskeleton septin ring cell cycle microtubule cytoskeleton cell junction septin complex septin complex septin complex cell division site cellular protein localization cell projection synapse regulation of synapse organization cell division molecular adaptor activity cytoskeleton-dependent cytokinesis postsynapse glutamatergic synapse GABA-ergic synapse postsynaptic specialization of symmetric synapse
TC1100003771.mm.2	Nt5c3b	5'-nucleotidase, cytosolic IIIB	11	-100429351, -100439552, -100422320	NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307	68106	15	nucleotide binding magnesium ion binding cytoplasm nucleotide metabolic process hydrolase activity metal ion binding
TC1900000748.mm.2	Add3	adducin 3 (gamma)	19	53140442, 53142755, 53143996	NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116	27360	31	condensed nuclear chromosome actin binding protein kinase C binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton cytoskeleton plasma membrane brush border cell-cell junction cell cortex postsynaptic density postsynaptic density membrane response to drug positive regulation of vasoconstriction actin filament binding barbed-end actin filament capping
TC1300001069.mm.2	Wdr41	WD repeat domain 41	13	94976343	NM_172590, BC138095, BC145144 NM_172590, BC138095, BC145144 NM_172590, BC138095, BC145144	218460	18	guanyl-nucleotide exchange factor activity cytoplasm cytoplasm autophagy regulation of autophagy guanyl-nucleotide exchange factor complex Atg1/ULK1 kinase complex
TC1900000560.mm.2	Hells	helicase, lymphoid specific	19	38930989	NM_008234, BC100394 NM_008234, BC100394	15201	65	nucleotide binding chromosome, centromeric region urogenital system development chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus pericentric heterochromatin pericentric heterochromatin DNA methylation DNA methylation chromatin silencing DNA methylation-dependent heterochromatin assembly DNA methylation-dependent heterochromatin assembly cell cycle multicellular organism development maintenance of DNA methylation maintenance of DNA methylation hydrolase activity lymphocyte differentiation pericentric heterochromatin assembly pericentric heterochromatin assembly negative regulation of apoptotic process lymphocyte proliferation lymphocyte proliferation cell division cellular response to leukemia inhibitory factor negative regulation of intrinsic apoptotic signaling pathway
TC0100000836.mm.2					NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969			retinoic acid binding enzyme inhibitor activity protein kinase C binding steroid binding fatty acid binding mitochondrial inner membrane endoplasmic reticulum integral component of plasma membrane estrogen catabolic process drug binding estrogen metabolic process response to organic substance glucuronosyltransferase activity glucuronosyltransferase activity membrane membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups aromatic compound catabolic process glucuronate metabolic process glucuronate metabolic process enzyme binding bile acid secretion protein-containing complex endoplasmic reticulum chaperone complex protein homodimerization activity intracellular membrane-bounded organelle intracellular membrane-bounded organelle protein-containing complex binding coumarin catabolic process protein heterodimerization activity flavone metabolic process cellular glucuronidation flavonoid glucuronidation flavonoid glucuronidation xenobiotic glucuronidation xenobiotic glucuronidation cytochrome complex vitamin D3 metabolic process biphenyl catabolic process negative regulation of cellular glucuronidation
TC1400002836.mm.2	Dok2	docking protein 2	14	70774380	NM_010071, BC004590 NM_010071, BC004590	13449	54	transmembrane receptor protein tyrosine kinase adaptor activity protein binding transmembrane receptor protein tyrosine kinase signaling pathway Ras protein signal transduction negative regulation of MAPK cascade
TC0100001227.mm.2	Cyb5r1	cytochrome b5 reductase 1	1	134405780	NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618	72017	21	cytochrome-b5 reductase activity, acting on NAD(P)H mitochondrion lipid metabolic process steroid biosynthetic process steroid metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity FAD binding	00520
TC1900000171.mm.2					NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786			protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction actin cytoskeleton actin cytoskeleton vesicle vesicle sarcolemma identical protein binding costamere costamere regulation of RNA splicing regulation of RNA splicing cell-cell contact zone cell-cell contact zone S100 protein binding membrane raft membrane raft extracellular exosome structural molecule activity conferring elasticity regulation of voltage-gated calcium channel activity
TC1200001314.mm.2	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	12	117516525, 117533927	NM_175930, BC046627 NM_175930, BC046627	217944	25	guanyl-nucleotide exchange factor activity intracellular anatomical structure nucleus nucleoplasm small GTPase mediated signal transduction nuclear body GTP-dependent protein binding intracellular signal transduction
TC0700001122.mm.2	Fanci	Fanconi anemia, complementation group I	7	79392337	NM_145946	208836	25	nucleus nucleoplasm cytoplasm cytosol DNA repair cellular response to DNA damage stimulus cell cycle positive regulation of protein ubiquitination Fanconi anaemia nuclear complex DNA polymerase binding DNA polymerase binding
TC0200005052.mm.2	Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	2	-160363676	NM_010658, BC016434, BC038256 NM_010658, BC016434, BC038256 NM_010658, BC016434, BC038256	16658	255	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II segment specification respiratory gaseous exchange by respiratory system transcription factor binding rhombomere 5 development rhombomere 6 development abducens nerve formation T cell differentiation in thymus brain segmentation inner ear morphogenesis identical protein binding sequence-specific DNA binding protein-containing complex binding regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation negative regulation of osteoclast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development sequence-specific double-stranded DNA binding
TC0700002950.mm.2	Cd33	CD33 antigen	7	-43527455	NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33	12489	24	plasma membrane cell adhesion external side of plasma membrane membrane integral component of membrane carbohydrate binding sialic acid binding	04640
TC0300003225.mm.2					BC145417, BC145418, NM_001173459 BC145417, BC145418, NM_001173459 BC145417, BC145418, NM_001173459			molecular_function plasma membrane plasma membrane intracellular signal transduction positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of T cell activation
TC0100002974.mm.2	Ddx18	DEAD box helicase 18	1	-121553834	NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231	66942	25	nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleic acid binding RNA binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus hydrolase activity
TC0100000682.mm.2					NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102			nucleotide binding long-chain fatty acid metabolic process long-chain fatty acid metabolic process catalytic activity long-chain fatty acid-CoA ligase activity long-chain fatty acid-CoA ligase activity ATP binding nucleus nucleolus nucleolus mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum endoplasmic reticulum Golgi apparatus lipid droplet lipid droplet cytosol plasma membrane rRNA processing lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development spermatogenesis membrane integral component of membrane ligase activity protein kinase binding protein domain specific binding cell differentiation neuron differentiation small-subunit processome very-low-density lipoprotein particle assembly long-chain fatty-acyl-CoA metabolic process ribosome biogenesis positive regulation of Golgi to plasma membrane protein transport intracellular membrane-bounded organelle long-chain fatty acid import into cell arachidonate-CoA ligase activity perinuclear region of cytoplasm positive regulation of secretion meiotic cell cycle decanoate-CoA ligase activity positive regulation of phosphatidylcholine biosynthetic process
TC0X00002993.mm.2	Timm8a1	translocase of inner mitochondrial membrane 8A1	X	11609223, -134537255	NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631	30058	26	mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space protein targeting to mitochondrion zinc ion binding protein transport membrane identical protein binding metal ion binding chaperone-mediated protein transport
TC0200004568.mm.2	Bub1	BUB1, mitotic checkpoint serine/threonine kinase	2	-127800199	NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116	12235	63	nucleotide binding chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed nuclear chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm chromosome cytosol protein phosphorylation apoptotic process cell cycle chromosome segregation regulation of sister chromatid cohesion mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity intracellular membrane-bounded organelle cell division meiotic sister chromatid cohesion, centromeric regulation of chromosome segregation mitotic spindle checkpoint positive regulation of intrinsic apoptotic signaling pathway	04110 04114 04914
TC0700001151.mm.2	Prc1	protein regulator of cytokinesis 1	7	80294475, 80294450	NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475	233406	44	microtubule cytoskeleton organization cytokinesis microtubule bundle formation nucleus nucleoplasm cytoplasm spindle spindle cytoskeleton microtubule plasma membrane cell cycle microtubule binding positive regulation of cell population proliferation microtubule cytoskeleton kinesin binding protein kinase binding midbody regulation of cytokinesis identical protein binding intercellular bridge mitotic spindle midzone assembly cell division contractile ring mitotic spindle midzone
TC1800000265.mm.2	Wdr36	WD repeat domain 36	18	32837224, 32837224, 32837224	NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453	225348	24	retina homeostasis nucleolus rRNA processing regulation of axon extension small-subunit processome Pwp2p-containing subcomplex of 90S preribosome	03008
TC0100000222.mm.2	Imp4	IMP4, U3 small nucleolar ribonucleoprotein	1	34439828	NM_178601, BC069930 NM_178601, BC069930	27993	20	fibrillar center nucleus nucleolus nucleolus rRNA processing snoRNA binding preribosome small-subunit processome Mpp10 complex Mpp10 complex ribosome biogenesis	03008
TC1600001527.mm.2	Umps	uridine monophosphate synthetase	16	-33954781	NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981	22247	30	catalytic activity orotate phosphoribosyltransferase activity orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity orotidine-5'-phosphate decarboxylase activity nucleus cytoplasm 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process UMP biosynthetic process metabolic process nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups lyase activity carboxy-lyase activity pyrimidine nucleobase biosynthetic process identical protein binding 'de novo' UMP biosynthetic process	00240 00983 01100
TC0200003717.mm.2	Mettl8	methyltransferase like 8	2	-70964560, -70964561	NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960	228019	18	histone acetyltransferase activity nucleus cytoplasm skeletal muscle tissue development methyltransferase activity mRNA methyltransferase activity mRNA methyltransferase activity histone acetylation transferase activity methylation fat cell differentiation tRNA (cytosine-3-)-methyltransferase activity mRNA methylation mRNA methylation
TC0X00001322.mm.2	Tceal9	transcription elongation factor A like 9	X	136245079	NM_011712, BC007478 NM_011712, BC007478	22381	19	nucleus WW domain binding WW domain binding
TC0800002878.mm.2	Nob1	NIN1/RPN12 binding protein 1 homolog	8	-107412488	NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993	67619	23	cleavage involved in rRNA processing nuclease activity endonuclease activity endoribonuclease activity endoribonuclease activity nucleus nucleolus cytoplasm visual perception hydrolase activity maturation of SSU-rRNA maturation of SSU-rRNA preribosome, small subunit precursor ribosomal small subunit biogenesis metal ion binding	03008
TC1700000990.mm.2	Adgre4	adhesion G protein-coupled receptor E4	17	55749983	NM_139138, BC120538, BC120540 NM_139138, BC120538, BC120540 NM_139138, BC120538, BC120540	52614	19	transmembrane signaling receptor activity G protein-coupled receptor activity calcium ion binding plasma membrane integral component of plasma membrane integral component of plasma membrane signal transduction cell surface receptor signaling pathway epidermal growth factor receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway cell surface membrane integral component of membrane
TC0100003500.mm.2	Nuf2	NUF2, NDC80 kinetochore complex component	1	-169497933	NM_023284, BC020026 NM_023284, BC020026	66977	22	chromosome, centromeric region kinetochore condensed nuclear chromosome kinetochore nucleus nucleoplasm chromosome cytosol cell cycle mitotic spindle organization attachment of spindle microtubules to kinetochore Ndc80 complex Ndc80 complex protein-containing complex binding meiotic chromosome segregation cell division attachment of mitotic spindle microtubules to kinetochore kinetochore organization
TC0800002927.mm.2	Sf3b3	splicing factor 3b, subunit 3	8	-110810491	NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016	101943	28	mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding nucleus nucleus nucleoplasm spliceosomal complex U2 snRNP U12-type spliceosomal complex nucleolus mRNA processing RNA splicing U2 snRNA binding negative regulation of protein catabolic process protein-containing complex binding U2-type precatalytic spliceosome catalytic step 2 spliceosome	03040
TC1700001938.mm.2	D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5	17	-34996723	BC027314	110956	28
TC0800001095.mm.2	Mt1	metallothionein 1	8	94179088	NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990	17748	335	copper ion binding nucleus cytoplasm lysosome cytosol cytosol cellular metal ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding detoxification of copper ion detoxification of copper ion negative regulation of neuron apoptotic process metal ion binding metal ion binding cellular response to chromate cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion cellular response to zinc ion
TC1300001574.mm.2	H2ac12	H2A clustered histone 12	13	-22035121	NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008	319168	11	nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity	05322
TC0700003592.mm.2	Man2a2	mannosidase 2, alpha 2	7	-80349096	NM_172903, BC055006 NM_172903, BC055006	140481	23	Golgi membrane catalytic activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing protein deglycosylation metabolic process mannosidase activity membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding	00510 01100
TC0400002007.mm.2	Dnajc11	DnaJ heat shock protein family (Hsp40) member C11	4	151933719	NM_172704, BC085257 NM_172704, BC085257	230935	32	SAM complex nucleoplasm mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane membrane nuclear speck cristae formation cristae formation cristae formation MICOS complex MICOS complex
TC1900000543.mm.2	Cep55	centrosomal protein 55	19	38054983, 38054983, 38055040	NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396	74107	31	mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm centrosome cytoskeleton plasma membrane cell cycle regulation of phosphatidylinositol 3-kinase signaling midbody midbody midbody centriolar satellite identical protein binding intercellular bridge establishment of protein localization establishment of protein localization cell division midbody abscission Flemming body cranial skeletal system development
TC0400001465.mm.2	Clspn	claspin	4	126556979	NM_175554, BC050848 NM_175554, BC050848	269582	26	DNA replication checkpoint DNA damage checkpoint DNA secondary structure binding DNA binding nucleus nucleoplasm chromosome Golgi apparatus DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint anaphase-promoting complex binding anaphase-promoting complex binding peptidyl-serine phosphorylation activation of protein kinase activity activation of protein kinase activity mitotic DNA replication checkpoint mitotic DNA replication checkpoint
TC0900001987.mm.2	Fli1	Friend leukemia integration 1	9	-32422203	NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792	14247	133	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleus nucleus nucleoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II blood circulation animal organ morphogenesis cellular process nuclear body cell differentiation megakaryocyte development sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding
TC1300002543.mm.2	Ccnb1	cyclin B1	13	-100778738	NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238	268697	210	regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex spindle pole condensed nuclear chromosome outer kinetochore oocyte maturation in utero embryonic development negative regulation of protein phosphorylation patched binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm mitochondrial matrix mitochondrial matrix mitochondrial matrix centrosome centrosome cytosol cytoskeleton protein phosphorylation cell cycle mitotic spindle organization mitotic metaphase plate congression mitotic metaphase plate congression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding positive regulation of mRNA 3'-end processing positive regulation of histone phosphorylation ubiquitin-like protein ligase binding mitotic cell cycle phase transition protein-containing complex binding positive regulation of cell cycle positive regulation of mitotic cell cycle positive regulation of fibroblast proliferation cell division positive regulation of attachment of spindle microtubules to kinetochore positive regulation of cardiac muscle cell proliferation regulation of chromosome condensation cyclin-dependent protein serine/threonine kinase activator activity protein-containing complex assembly regulation of mitotic cell cycle spindle assembly checkpoint cyclin B1-CDK1 complex cyclin B1-CDK1 complex positive regulation of mitochondrial ATP synthesis coupled electron transport histone H3-S10 phosphorylation involved in chromosome condensation	04110 04114 04115 04914
TC1100003817.mm.2	Dusp3	dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)	11	-101971143	NM_028207, BC016269 NM_028207, BC016269	72349	39	inactivation of MAPK activity in utero embryonic development immunological synapse phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm cytosol cytosol protein dephosphorylation cytoskeletal protein binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/serine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity protein kinase binding negative regulation of cell migration receptor tyrosine kinase binding MAP kinase phosphatase activity MAP kinase phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation negative regulation of epidermal growth factor receptor signaling pathway negative regulation of MAPK cascade positive regulation of mitotic cell cycle positive regulation of mitotic cell cycle negative regulation of JNK cascade negative regulation of JNK cascade negative regulation of T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway negative regulation of T cell activation negative regulation of T cell activation negative regulation of chemotaxis regulation of focal adhesion assembly regulation of focal adhesion assembly negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus cellular response to epidermal growth factor stimulus positive regulation of focal adhesion disassembly peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity protein tyrosine kinase binding	04010
TC0900002036.mm.2	Chek1	checkpoint kinase 1	9	-36708481	NM_007691, BC100386 NM_007691, BC100386	12649	117	DNA damage checkpoint DNA damage checkpoint DNA damage checkpoint G2/M transition of mitotic cell cycle nucleotide binding chromosome, telomeric region chromatin condensed nuclear chromosome inner cell mass cell proliferation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome cytoplasm cytoplasm centrosome cytoskeleton DNA repair DNA repair protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus DNA damage induced protein phosphorylation nucleus organization cell cycle mitotic cell cycle checkpoint regulation of gene expression regulation of double-strand break repair via homologous recombination regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage negative regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-threonine phosphorylation protein domain specific binding protein-containing complex histone kinase activity (H3-T11 specific) histone kinase activity (H3-T11 specific) intracellular signal transduction regulation of cell population proliferation intracellular membrane-bounded organelle mitotic G2/M transition checkpoint positive regulation of cell cycle negative regulation of mitotic nuclear division regulation of mitotic centrosome separation chromatin-mediated maintenance of transcription signal transduction involved in G2 DNA damage checkpoint apoptotic process involved in development negative regulation of DNA biosynthetic process regulation of histone H3-K9 acetylation	04110 04115
TC1400000777.mm.2	Dhrs4	dehydrogenase/reductase (SDR family) member 4	14	55478757, 55478757	NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361	28200	24	3-keto sterol reductase activity retinal dehydrogenase activity carbonyl reductase (NADPH) activity nucleus mitochondrion peroxisome peroxisome peroxisomal membrane alcohol metabolic process steroid metabolic process oxidoreductase activity oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor alcohol dehydrogenase [NAD(P)+] activity cellular ketone metabolic process retinal metabolic process identical protein binding	00830 01100 04146
TC0700003581.mm.2	Idh2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	7	-80094846	NM_173011, BC060030 NM_173011, BC060030	269951	84	magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane peroxisome cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process NADP metabolic process NADP biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding NAD binding negative regulation of glial cell proliferation negative regulation of glial cell migration negative regulation of matrix metallopeptidase secretion	00020 00480 01100 04146
TC1300002463.mm.2	Iqgap2	IQ motif containing GTPase activating protein 2	13	-95627176	NM_027711, BC150958 NM_027711, BC150958	544963	39	GTPase activator activity calmodulin binding calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytoplasm microtubule microvillus signal transduction cell surface lamellipodium filopodium small GTPase binding regulation of actin cytoskeleton organization Arp2/3 complex-mediated actin nucleation regulation of GTPase activity actin filament binding actin filament binding thrombin-activated receptor signaling pathway Arp2/3 complex binding regulation of actin cytoskeleton reorganization	04810
TC1400001671.mm.2	Stab1	stabilin 1	14	-31139016	NM_138672	192187	42	low-density lipoprotein particle receptor activity scavenger receptor activity calcium ion binding hyaluronic acid binding cytoplasm integral component of plasma membrane inflammatory response cell adhesion cell-cell signaling membrane integral component of membrane negative regulation of angiogenesis low-density lipoprotein particle binding defense response to bacterium
TC0600001398.mm.2	Clec4a3	C-type lectin domain family 4, member a3	6	122952514, 122952643	NM_001204241, NM_153197, BC034893 NM_001204241, NM_153197, BC034893 NM_001204241, NM_153197, BC034893	73149	11	molecular_function cellular_component biological_process
TC0900002451.mm.2	Kif23	kinesin family member 23	9	-61917277	NM_024245, BC047273 NM_024245, BC047273	71819	34	nucleotide binding mitotic cytokinesis actomyosin contractile ring assembly microtubule motor activity ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle microtubule binding microtubule binding ATPase activity midbody positive regulation of cytokinesis intercellular bridge mitotic spindle midzone assembly mitotic spindle midzone assembly cell division plus-end-directed vesicle transport along microtubule mitotic spindle Flemming body centralspindlin complex
TC0100002772.mm.2					NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379			chromosome, centromeric region chromosome, centromeric region condensed chromosome kinetochore DNA binding nucleus nucleoplasm chromosome nucleolus mitochondrion cell cycle chromosome segregation CENP-A containing nucleosome assembly histone binding identical protein binding regulation of protein-containing complex assembly regulation of DNA binding
TC1000001546.mm.2	Cdk4	cyclin-dependent kinase 4	10	127063534	NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694	12567	327	G1/S transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex chromatin protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex nucleolus cytoplasm cytosol bicellular tight junction protein phosphorylation protein phosphorylation protein phosphorylation cell cycle signal transduction positive regulation of cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity response to organic substance response to lead ion regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane kinase activity phosphorylation mediator complex transferase activity cyclin binding cyclin binding nuclear membrane cellular response to insulin stimulus protein-containing complex response to testosterone regulation of multicellular organism growth regulation of cell population proliferation positive regulation of apoptotic process protein-containing complex binding positive regulation of translation positive regulation of cell size regulation of insulin receptor signaling pathway regulation of lipid biosynthetic process positive regulation of fibroblast proliferation perinuclear region of cytoplasm regulation of lipid catabolic process cell division regulation of cell cycle regulation of cell cycle adipose tissue development negative regulation of cell cycle arrest cellular response to lipopolysaccharide cellular response to interleukin-4 cyclin D2-CDK4 complex cellular response to phorbol 13-acetate 12-myristate cellular response to ionomycin	04110 04115 04530 04660 05200 05212 05214 05218 05219 05220 05222 05223
TC1400001665.mm.2					NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996			nucleotide binding molecular_function protein binding GTP binding GTP binding cellular_component nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus biological_process cell population proliferation nuclear body stem cell division stem cell population maintenance midbody positive regulation of telomere maintenance positive regulation of protein sumoylation regulation of cell population proliferation mRNA 5'-UTR binding positive regulation of pri-miRNA transcription by RNA polymerase II positive regulation of protein localization to chromosome, telomeric region
TC0600003268.mm.2	Ybx3	Y box protein 3	6	-131364857	NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377	56449	53	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development nucleic acid binding DNA binding single-stranded DNA binding single-stranded DNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm cytosol gap junction spermatogenesis male gonad development fertilization regulation of gene expression ribonucleoprotein complex binding negative regulation of apoptotic process positive regulation of organ growth negative regulation of skeletal muscle tissue development negative regulation of necroptotic process cellular response to tumor necrosis factor cellular hyperosmotic response negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress polysome binding	04530
TC0300002797.mm.2	S1pr1	sphingosine-1-phosphate receptor 1	3	-115710432	NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023	13609	252	angiogenesis angiogenesis G protein-coupled receptor binding blood vessel maturation cardiac muscle tissue growth involved in heart morphogenesis sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway G protein-coupled receptor activity G protein-coupled receptor activity nucleoplasm cytoplasm endosome plasma membrane chemotaxis signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway brain development positive regulation of cell population proliferation external side of plasma membrane membrane integral component of membrane cell migration regulation of metabolic process lamellipodium assembly regulation of cell adhesion positive regulation of cell migration regulation of bone mineralization leukocyte chemotaxis intrinsic component of plasma membrane actin cytoskeleton reorganization sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity intracellular membrane-bounded organelle positive regulation of GTPase activity regulation of bone resorption positive regulation of transcription by RNA polymerase II sphingolipid binding positive regulation of smooth muscle cell proliferation positive regulation of positive chemotaxis positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway negative regulation of stress fiber assembly heart trabecula morphogenesis T cell migration	04080
TC1100003399.mm.2	Ccl6	chemokine (C-C motif) ligand 6	11	-83587885	NM_009139, BC002073 NM_009139, BC002073	20305	34	monocyte chemotaxis cytokine activity extracellular region extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity chemokine activity neutrophil chemotaxis positive regulation of GTPase activity CCR chemokine receptor binding lymphocyte chemotaxis cell chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor	04060 04062
TC0900001792.mm.2	Fat3	FAT atypical cadherin 3	9	-15910189	NM_001080814	270120	25	cell morphogenesis involved in differentiation neuron migration calcium ion binding plasma membrane cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules multicellular organism development retina layer formation membrane integral component of membrane dendrite cell-cell adhesion negative regulation of dendrite development
TC0500003169.mm.2	Tpcn1	two pore channel 1	5	-120534156	NM_145853, BC058951 NM_145853, BC058951	252972	40	ion channel activity voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated sodium channel activity calcium channel activity lysosome lysosomal membrane lysosomal membrane endosome ion transport calcium ion transport endosome membrane endosome membrane positive regulation of autophagy ligand-gated sodium channel activity membrane integral component of membrane regulation of ion transmembrane transport sodium ion transmembrane transport identical protein binding protein homodimerization activity transmembrane transport calcium ion transmembrane transport NAADP-sensitive calcium-release channel activity NAADP-sensitive calcium-release channel activity phosphatidylinositol-3,5-bisphosphate binding
TC0900002044.mm.2	Slc37a2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2	9	-37229148	NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326	56857	18	endoplasmic reticulum glycerol-3-phosphate metabolic process glycerophosphate shuttle carbohydrate transport glycerol-3-phosphate transmembrane transporter activity antiporter activity glucose-6-phosphate transport glucose-6-phosphate transport glycerol-3-phosphate transmembrane transport membrane integral component of membrane transmembrane transporter activity integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane phosphate ion transmembrane transport phosphate ion transmembrane transport transmembrane transport glucose 6-phosphate:inorganic phosphate antiporter activity glucose 6-phosphate:inorganic phosphate antiporter activity
TC0100001058.mm.2	Nifk	nucleolar protein interacting with the FHA domain of MKI67	1	118321842	NM_026472, BC058559 NM_026472, BC058559	67949	21	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed nuclear chromosome nucleic acid binding RNA binding RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm
TC0700000896.mm.2	Nav2	neuron navigator 2	7	49246188, 48959072	NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112	78286	34	regulation of systemic arterial blood pressure by baroreceptor feedback interstitial matrix nucleoplasm nervous system development nervous system development sensory perception of sound sensory perception of smell locomotory behavior heparin binding optic nerve development glossopharyngeal nerve development vagus nerve development cerebellar cortex development extracellular matrix 3'-5' DNA helicase activity
TC0300002955.mm.2	Hadh	hydroxyacyl-Coenzyme A dehydrogenase	3	-131233419	NM_008212, BC064712 NM_008212, BC064712	15107	40	3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity protein binding nucleoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation response to activity oxidoreductase activity response to drug identical protein binding negative regulation of insulin secretion regulation of insulin secretion NAD+ binding positive regulation of cold-induced thermogenesis	00062 00071 00280 00310 00380 00650 01100
TC0500002231.mm.2	Mxd4	Max dimerization protein 4	5	-34176579	NM_010753, BC011303 NM_010753, BC011303	17122	31	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding protein binding nucleus regulation of transcription by RNA polymerase II negative regulation of transcription, DNA-templated protein dimerization activity RNA polymerase II transcription regulator complex
TC0300001757.mm.2	Ect2	ect2 oncogene	3	-27097221, -27097221	NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614	13605	48	mitotic cytokinesis mitotic cytokinesis cell morphogenesis guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytoskeleton cell-cell junction bicellular tight junction cell cortex cell cycle nervous system development protein transport nuclear body cell junction cell differentiation midbody small GTPase binding activation of protein kinase activity cleavage furrow positive regulation of cytokinesis regulation of Rho protein signal transduction intracellular signal transduction positive regulation of protein import into nucleus protein homodimerization activity positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of neuron differentiation regulation of protein kinase activity protein homooligomerization cell division regulation of attachment of spindle microtubules to kinetochore cellular response to hydrogen peroxide bicellular tight junction assembly cellular response to calcium ion cellular response to ionizing radiation mitotic spindle activation of GTPase activity activation of GTPase activity centralspindlin complex regulation of cytokinesis, actomyosin contractile ring assembly
TC1000001579.mm.2	Prim1	DNA primase, p49 subunit	10	128015214	NM_008921, BC089544 NM_008921, BC089544	19075	29	DNA primase activity DNA primase activity DNA-directed 5'-3' RNA polymerase activity protein binding alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer transferase activity nucleotidyltransferase activity metal ion binding primosome complex	00230 00240 01100 03030
TC1100004157.mm.2	Timp2	tissue inhibitor of metalloproteinase 2	11	-118301060	NM_011594, BC049126 NM_011594, BC049126	21858	152	protease binding protease binding enzyme inhibitor activity integrin binding integrin binding extracellular region basement membrane extracellular space extracellular space extracellular space enzyme activator activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation response to hormone cell surface cell surface response to organic substance negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity growth cone extracellular matrix regulation of Rap protein signal transduction response to cytokine neuron projection neuronal cell body regulation of MAPK cascade positive regulation of MAPK cascade regulation of neuron differentiation regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of adenylate cyclase activity negative regulation of proteolysis negative regulation of mitotic cell cycle negative regulation of Ras protein signal transduction metal ion binding negative regulation of membrane protein ectodomain proteolysis cellular response to organic substance negative regulation of metallopeptidase activity
TC0200003109.mm.2	Hnmt	histamine N-methyltransferase	2	-24002912	NM_080462, BC033928 NM_080462, BC033928	140483	21	regulation of neurotransmitter levels histamine metabolic process histamine catabolic process nucleoplasm cytoplasm centrosome cytosol methyltransferase activity N-methyltransferase activity transferase activity methylation neuron projection histamine N-methyltransferase activity	00340
TC0500003516.mm.2	Gna12	guanine nucleotide binding protein, alpha 12	5	-140759943	NM_010302, BC111810 NM_010302, BC111810	14673	87	nucleotide binding G protein-coupled receptor binding in utero embryonic development GTPase activity GTPase activity GTPase activity GTP binding cytoplasm heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway Rho protein signal transduction Rho protein signal transduction regulation of cell shape regulation of fibroblast migration membrane guanyl nucleotide binding cell differentiation brush border membrane brush border membrane G-protein beta/gamma-subunit complex binding D5 dopamine receptor binding D5 dopamine receptor binding regulation of TOR signaling regulation of TOR signaling regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of proteasomal ubiquitin-dependent protein catabolic process intracellular signal transduction embryonic digit morphogenesis metal ion binding negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration	04010 04270 04730 04810
TC0600000772.mm.2	Mad2l1	MAD2 mitotic arrest deficient-like 1	6	66535220	NM_019499, BC089012 NM_019499, BC089012	56150	81	mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore kinetochore spindle pole protein binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytoplasm cytosol cytoskeleton cell cycle mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint protein C-terminus binding negative regulation of protein catabolic process identical protein binding protein homodimerization activity negative regulation of apoptotic process negative regulation of apoptotic process nuclear pore nuclear basket negative regulation of mitotic metaphase/anaphase transition negative regulation of mitotic cell cycle perinuclear region of cytoplasm cell division establishment of centrosome localization mitotic spindle positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic cell cycle spindle assembly checkpoint negative regulation of ubiquitin protein ligase activity	04110 04114 04914
TC0200004207.mm.2	Ldlrad3	low density lipoprotein receptor class A domain containing 3	2	-101950200	NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510	241576	17	amyloid-beta binding plasma membrane receptor-mediated endocytosis membrane integral component of membrane regulation of protein processing
TC0200001906.mm.2	Blvra	biliverdin reductase A	2	127070656	NM_026678, BC052146 NM_026678, BC052146	109778	37	nucleotide binding biliverdin reductase (NAD(P)+) activity biliverdin reductase (NAD(P)+) activity biliverdin reductase (NAD(P)+) activity cytoplasm cytosol zinc ion binding oxidoreductase activity heme catabolic process metal ion binding	00860
TC0100003679.mm.2	Ephx1	epoxide hydrolase 1, microsomal	1	-180989555	NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493	13849	51	catalytic activity epoxide hydrolase activity endoplasmic reticulum plasma membrane cellular aromatic compound metabolic process response to toxic substance response to organic cyclic compound membrane integral component of membrane hydrolase activity arachidonic acid metabolic process aromatic compound catabolic process enzyme binding cis-stilbene-oxide hydrolase activity diol biosynthetic process intracellular membrane-bounded organelle epoxide metabolic process	00980 04976
TC0600001448.mm.2	Nop2	NOP2 nucleolar protein	6	125131882	NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151	110109	37	ribosomal large subunit assembly maturation of LSU-rRNA RNA methylation blastocyst formation RNA binding nucleus nucleolus nucleolus rRNA processing methyltransferase activity positive regulation of cell population proliferation S-adenosylmethionine-dependent methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity transferase activity methylation ribosome biogenesis rRNA base methylation regulation of signal transduction by p53 class mediator
TC0300000693.mm.2	Cd5l	CD5 antigen-like	3	87357880	NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like	11801	46	immune system process serine-type endopeptidase activity scavenger receptor activity extracellular region cytoplasm plasma membrane plasma membrane apoptotic process inflammatory response cell surface cell surface membrane regulation of complement activation zymogen activation positive regulation of complement-dependent cytotoxicity
TC0600001508.mm.2					NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723			G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding vasculogenesis liver development molecular_function DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding cellular_component nucleus nucleus DNA repair regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle biological_process positive regulation of cell population proliferation positive regulation of cell population proliferation protein kinase binding negative regulation of stress-activated MAPK cascade regulation of cell population proliferation regulation of cell population proliferation sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of Ras protein signal transduction regulation of cell cycle arrest regulation of cell cycle arrest negative regulation of cell aging regulation of reactive oxygen species metabolic process positive regulation of double-strand break repair positive regulation of double-strand break repair
TC1200001030.mm.2	Ifi27	interferon, alpha-inducible protein 27	12	103434188	NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276	52668	21	negative regulation of transcription by RNA polymerase II RNA polymerase II activating transcription factor binding lamin binding nuclear inner membrane mitochondrion regulation of protein export from nucleus apoptotic signaling pathway
TC0600001033.mm.2	Ruvbl1	RuvB-like protein 1	6	88465408	NM_019685, BC004718 NM_019685, BC004718	56505	53	nucleotide binding box C/D snoRNP assembly Swr1 complex Swr1 complex TFIID-class transcription factor complex binding DNA helicase activity DNA helicase activity transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm cytosol DNA repair DNA recombination chromatin organization chromatin remodeling regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus cell cycle positive regulation of plasminogen activation nuclear matrix histone acetylation hydrolase activity ATPase activity TBP-class protein binding Ino80 complex Ino80 complex protein-containing complex NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth 3'-5' DNA helicase activity 5'-3' DNA helicase activity ADP binding histone H4 acetylation histone H2A acetylation ATPase binding cell division MLL1 complex positive regulation of canonical Wnt signaling pathway R2TP complex R2TP complex ribonucleoprotein complex regulation of fibroblast apoptotic process	04310
TC1100003059.mm.2					NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441			angiogenesis immune system process immunoglobulin production in mucosal tissue positive regulation of germinal center formation cytokine activity tumor necrosis factor receptor binding extracellular region extracellular region extracellular space cytoplasm plasma membrane apoptotic process immune response multicellular organism development positive regulation of cell population proliferation external side of plasma membrane membrane integral component of membrane immunoglobulin mediated immune response cell differentiation positive regulation of protein catabolic process receptor ligand activity positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgA isotypes perinuclear region of cytoplasm regulation of immune response extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway
TC1300002654.mm.2	Gapt	Grb2-binding adaptor, transmembrane	13	-110352614	NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005	238875	14	B cell homeostasis B cell homeostasis B cell proliferation involved in immune response B cell proliferation involved in immune response immunoglobulin production involved in immunoglobulin-mediated immune response immunoglobulin production involved in immunoglobulin-mediated immune response Golgi apparatus plasma membrane membrane integral component of membrane B cell activation intracellular membrane-bounded organelle
TC1600001320.mm.2	Cdc45	cell division cycle 45	16	-18780446	NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635	12544	41	double-strand break repair via break-induced replication chromatin binding DNA replication origin binding single-stranded DNA binding nucleus nucleoplasm centrosome DNA replication DNA replication initiation cell cycle DNA replication preinitiation complex regulation of chromatin silencing at telomere ciliary basal body mitotic DNA replication preinitiation complex assembly	04110
TC0200001056.mm.2	Cdca7	cell division cycle associated 7	2	72476218	NM_025866, BC066169 NM_025866, BC066169	66953	36	molecular_function nucleus nucleus nucleoplasm cytoplasm cytosol regulation of transcription, DNA-templated apoptotic process regulation of cell population proliferation
TC1100002694.mm.2	Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	11	-51600099	NM_001048061, NM_010448, BC043069 NM_001048061, NM_010448, BC043069 NM_001048061, NM_010448, BC043069	15384	55	negative regulation of transcription by RNA polymerase II epithelial to mesenchymal transition nucleic acid binding DNA binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm regulation of gene expression positive regulation of transcription, DNA-templated RNA polymerase II transcription regulator complex presynaptic cytosol ribonucleoprotein complex
TC0100003505.mm.2	Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	1	-169949536	NM_010476	15490	38	3-keto sterol reductase activity 3-keto sterol reductase activity 3-keto sterol reductase activity estradiol 17-beta-dehydrogenase activity estradiol 17-beta-dehydrogenase activity prolactin receptor binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process estrogen biosynthetic process estrogen biosynthetic process nervous system development brain development androgen metabolic process androgen metabolic process membrane integral component of membrane oxidoreductase activity cell differentiation 5alpha-androstane-3beta,17beta-diol dehydrogenase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity embryonic organ development embryonic skeletal system development	00100 00140 01100
TC1000000402.mm.2	Cd24a	CD24a antigen	10	43579168	NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a	12484	167	response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation immune system process leukocyte migration involved in inflammatory response positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptotic process protein binding plasma membrane plasma membrane cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion cell surface receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuromuscular synaptic transmission neuromuscular synaptic transmission negative regulation of neuroblast proliferation apoptotic mitochondrial changes external side of plasma membrane external side of plasma membrane cell surface positive regulation of neuron projection development positive regulation of neuron projection development membrane membrane cell migration protein kinase binding regulation of cell-cell adhesion positive regulation of cell-cell adhesion carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity Hsp70 protein binding negative regulation of B cell proliferation neuron projection development neuron projection development anchored component of membrane T cell costimulation anchored component of external side of plasma membrane anchored component of external side of plasma membrane anchored component of external side of plasma membrane microvillus membrane chemokine receptor transport out of membrane raft negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of transforming growth factor beta3 production positive regulation of integrin activation positive regulation of integrin activation positive regulation of cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin regulation of cell-cell adhesion mediated by integrin positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPK cascade response to estrogen innate immune response membrane raft membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of neurogenesis positive regulation of calcium-mediated signaling Hsp90 protein binding ciliary membrane negative regulation of monocyte chemotactic protein-1 production apoptotic signaling pathway negative regulation of inflammatory response to wounding positive regulation of inflammatory response to wounding	04640
TC1100001634.mm.2	Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1	11	101010397, 101009440, 101009440, 101009440	NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182	11975	48	vacuolar proton-transporting V-type ATPase, V0 domain protein binding cytoplasm Golgi apparatus cytosol plasma membrane plasma membrane ion transport vacuolar acidification synaptic vesicle proton transmembrane transporter activity membrane integral component of membrane regulation of macroautophagy vacuolar proton-transporting V-type ATPase complex nuclear speck integral component of synaptic vesicle membrane cytoplasmic vesicle proton-transporting V-type ATPase, V0 domain intracellular organelle intracellular membrane-bounded organelle proton-transporting ATPase activity, rotational mechanism perinuclear region of cytoplasm ATPase binding ATPase binding toxin transport proton transmembrane transport	00190 01100 04142 04145 04966 05323
TC1100003434.mm.2	Brip1	BRCA1 interacting protein C-terminal helicase 1	11	-86058135	NM_178309, BC094252 NM_178309, BC094252	237911	22	nucleotide binding nucleic acid binding DNA binding DNA helicase activity chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm cytoplasm nucleobase-containing compound metabolic process DNA repair nucleotide-excision repair regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus homologous chromosome pairing at meiosis spermatogenesis spermatogonial cell division spermatid development negative regulation of cell population proliferation male gonad development negative regulation of gene expression meiotic DNA double-strand break processing involved in reciprocal meiotic recombination hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides nuclear membrane metal ion binding chiasma assembly iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding seminiferous tubule development double-strand break repair involved in meiotic recombination double-strand break repair involved in meiotic recombination
TC0100001381.mm.2	Rgs16	regulator of G-protein signaling 16	1	153740352	NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459	19734	45	GTPase activator activity GTPase activator activity GTPase activator activity protein binding cytoplasm cytoplasm G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway negative regulation of signal transduction membrane intrinsic component of membrane positive regulation of GTPase activity positive regulation of GTPase activity membrane raft
TC1200001460.mm.2	Lpin1	lipin 1	12	-16535668, -16535668	NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462	14245	127	negative regulation of transcription by RNA polymerase II mitochondrial fission RNA polymerase II transcription factor binding transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus transcription regulator complex cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum DNA replication regulation of transcription by RNA polymerase II lipid metabolic process triglyceride mobilization immune response phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity fatty acid catabolic process fatty acid catabolic process membrane hydrolase activity triglyceride biosynthetic process positive regulation of histone deacetylation ruffle organization actin cytoskeleton reorganization negative regulation of myelination nuclear membrane cellular response to insulin stimulus cellular response to insulin stimulus cellular response to insulin stimulus histone deacetylase binding peroxisome proliferator activated receptor binding cellular lipid metabolic process cellular lipid metabolic process fat cell differentiation regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II phosphatidic acid metabolic process positive regulation of cold-induced thermogenesis regulation of phosphatidate phosphatase activity
TC0500000008.mm.2	Cdk6	cyclin-dependent kinase 6	5	3343892	NM_009873, BC119360, BC120595 NM_009873, BC119360, BC120595 NM_009873, BC119360, BC120595	12571	139	negative regulation of transcription by RNA polymerase II nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion hematopoietic progenitor cell differentiation type B pancreatic cell development protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome cytosol cytoskeleton protein phosphorylation protein phosphorylation cell cycle Notch signaling pathway Notch signaling pathway RNA polymerase II CTD heptapeptide repeat kinase activity regulation of gene expression positive regulation of gene expression kinase activity phosphorylation mediator complex transferase activity hemopoiesis cell differentiation cyclin binding T cell differentiation in thymus response to 5-fluorouracil gliogenesis regulation of cell population proliferation cell projection cell dedifferentiation cell quiescence negative regulation of myeloid cell differentiation regulation of erythrocyte differentiation negative regulation of monocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division regulation of cell cycle hematopoietic stem cell differentiation cyclin D2-CDK6 complex FBXO family protein binding regulation of hematopoietic stem cell differentiation negative regulation of cellular senescence	04110 04115 05200 05212 05214 05218 05220 05222 05223
TC1400001031.mm.2	Rcbtb2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	14	73142509, 73142784	NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224	105670	17	acrosomal vesicle molecular_function biological_process cytoplasmic vesicle
TC1200000596.mm.2	Frmd6	FERM domain containing 6	12	70825513	NM_028127, BC053929 NM_028127, BC053929	319710	24	apical constriction protein binding cytoplasm cytoskeleton plasma membrane membrane actomyosin structure organization regulation of actin filament-based process cellular protein localization apical junction complex
TC0400001158.mm.2	Kti12	KTI12 homolog, chromatin associated	4	108847856	NM_029571, BC021493 NM_029571, BC021493	100087	12	nucleotide binding tRNA wobble uridine modification molecular_function ATP binding regulation of transcription by RNA polymerase II elongator holoenzyme complex
TC1300000260.mm.2	H2ac4	H2A clustered histone 4	13	23751087	NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047	319172	7	DNA binding nucleus chromatin silencing	05322
TC1000000422.mm.2	Prep	prolyl endopeptidase	10	45067215	NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830	19072	58	endopeptidase activity endopeptidase activity serine-type endopeptidase activity nucleus cytoplasm cytosol cytosol proteolysis peptidase activity serine-type peptidase activity hydrolase activity protein metabolic process peptide binding serine-type exopeptidase activity oligopeptidase activity
TC1400002231.mm.2	Msra	methionine sulfoxide reductase A	14	-64122620, -64122620, -64122620, -64122620, -64122620	NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311	110265	79	nucleus nucleoplasm cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion cytosol plasma membrane aging peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity actin cytoskeleton membrane oxidoreductase activity cellular response to oxidative stress L-methionine-(S)-S-oxide reductase activity
TC0400001129.mm.2	Ndc1	NDC1 transmembrane nucleoporin	4	107368046	NM_028355, BC021337 NM_028355, BC021337	72787	28	nucleus nuclear pore nuclear pore cytoplasm plasma membrane nuclear pore organization homologous chromosome pairing at meiosis spermatogenesis protein transport actin cytoskeleton membrane integral component of membrane structural constituent of nuclear pore protein-macromolecule adaptor activity nuclear membrane mRNA transport nuclear pore complex assembly nuclear pore localization nuclear pore transmembrane ring	03013
TC1400000980.mm.2	Entpd4	ectonucleoside triphosphate diphosphohydrolase 4	14	69337150, 69555400	NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931	67464	23	Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane	00230 00240 04142
TC1100000573.mm.2	Nhp2	NHP2 ribonucleoprotein	11	51619772	NM_026631, BC024944 NM_026631, BC024944	52530	29	cleavage involved in rRNA processing maturation of LSU-rRNA RNA binding RNA binding protein binding nucleus telomerase holoenzyme complex nucleolus rRNA processing telomere maintenance via telomerase rRNA pseudouridine synthesis snRNA pseudouridine synthesis box H/ACA snoRNP complex box H/ACA snoRNP complex box H/ACA snoRNA binding box H/ACA snoRNA binding ribosome biogenesis telomerase RNA binding box H/ACA telomerase RNP complex	03008
TC0600000570.mm.2	Tmem176a	transmembrane protein 176A	6	48841655, 48841482	NM_001098271, NM_025326, BC010831 NM_001098271, NM_025326, BC010831 NM_001098271, NM_025326, BC010831	66058	18	protein binding membrane integral component of membrane negative regulation of dendritic cell differentiation negative regulation of dendritic cell differentiation
TC0300001488.mm.2	Mcoln3	mucolipin 3	3	146121790	NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857	171166	53	cation channel activity cytoplasm lysosomal membrane endosome plasma membrane plasma membrane ion transport sensory perception of sound locomotory behavior lipid binding membrane integral component of membrane cytoplasmic vesicle inner ear auditory receptor cell differentiation cell projection NAADP-sensitive calcium-release channel activity
TC1100004128.mm.2	Srsf2	serine and arginine-rich splicing factor 2	11	-116849896	NM_011358, BC005493 NM_011358, BC005493	20382	92	regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding protein kinase C binding protein binding nucleus nucleus nucleoplasm spliceosomal complex cytoplasm cytosol mRNA processing RNA splicing nuclear speck nuclear speck nuclear speck interchromatin granule pre-mRNA binding regulation of RNA splicing	03040
TC0600001852.mm.2	Ica1	islet cell autoantigen 1	6	-8630526, -8630526	NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030	15893	37	Golgi membrane protein binding cytoplasm Golgi apparatus Golgi stack cytosol cytosol neurotransmitter transport membrane protein domain specific binding cell junction dendrite secretory granule membrane synaptic vesicle membrane cytoplasmic vesicle intracellular membrane-bounded organelle regulation of protein-containing complex assembly synapse regulation of neurotransmitter secretion perinuclear region of cytoplasm regulation of insulin secretion regulation of transport membrane curvature sensor activity	04940
TC0200001972.mm.2					NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355			fibrillar center molecular_function RNA binding cellular_component nucleus sno(s)RNA-containing ribonucleoprotein complex cytoplasm biological_process snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis pre-snoRNP complex histone methyltransferase binding
TC1600002082.mm.2	Gart	phosphoribosylglycinamide formyltransferase	16	-91621396	NM_010256, BC070465 NM_010256, BC070465	14450	40	nucleotide binding catalytic activity phosphoribosylamine-glycine ligase activity phosphoribosylamine-glycine ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylglycinamide formyltransferase activity ATP binding cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glycine metabolic process metabolic process biosynthetic process purine nucleobase biosynthetic process ribonucleoside monophosphate biosynthetic process response to organic substance response to inorganic substance transferase activity hydroxymethyl-, formyl- and related transferase activity ligase activity adenine biosynthetic process tetrahydrofolate biosynthetic process metal ion binding	00230 00670 01100
TC0900001210.mm.2	Tfdp2	transcription factor Dp 2	9	96259247, 96196274, 96258704	NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080	211586	37	mitotic cell cycle RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity transcription coregulator activity protein binding nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle transcription factor binding protein domain specific binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of cell cycle mitotic spindle RNA polymerase II transcription regulator complex	04110
TC1300000240.mm.2					NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303			nuclear chromosome nucleosome DNA binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly chromatin silencing negative regulation of cell population proliferation enzyme binding protein-containing complex regulation of gene silencing
TC0100002481.mm.2	Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	1	-65158615, -65158615	NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986	15926	147	magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisome cytosol cytosol cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process isocitrate metabolic process 2-oxoglutarate metabolic process NADP metabolic process glutathione metabolic process response to oxidative stress response to organic cyclic compound oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding protein homodimerization activity metal ion binding response to steroid hormone NADP binding NAD binding regulation of phospholipid catabolic process regulation of phospholipid biosynthetic process	00020 00480 01100 04146
TC1200001348.mm.2	Efr3b	EFR3 homolog B	12	-3962553	NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968	668212	14	molecular_function cytoplasm cytosol plasma membrane plasma membrane actin cytoskeleton membrane phosphatidylinositol phosphorylation protein localization to plasma membrane protein localization to plasma membrane
TC0900000854.mm.2	Pclaf	PCNA clamp associated factor	9	65890322	NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393	68026	31	chromatin binding chromatin binding nucleus nucleus cytoplasm centrosome DNA replication DNA repair cellular response to DNA damage stimulus centrosome cycle response to UV translesion synthesis translesion synthesis perinuclear region of cytoplasm regulation of cell cycle
TC0700003024.mm.2	Grwd1	glutamate-rich WD repeat containing 1	7	-45825225, -45825222	NM_153419, BC028896 NM_153419, BC028896	101612	19	chromatin binding DNA replication origin binding nucleus nucleoplasm chromosome nucleolus cytosol DNA replication nucleosome assembly nucleosome disassembly protein-containing complex histone binding
TC0600000711.mm.2	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	6	58596671, 58584532, 58640545, 58595959	NM_011920, BC053730 NM_011920, BC053730	26357	176	nucleotide binding ATP binding nucleus nucleoplasm mitochondrion plasma membrane plasma membrane plasma membrane cytoskeletal protein binding organic anion transmembrane transporter activity ABC-type xenobiotic transporter activity urate transmembrane transporter activity biotin transmembrane transporter activity efflux transmembrane transporter activity efflux transmembrane transporter activity organic anion transport urate transport biotin transport membrane integral component of membrane apical plasma membrane apical plasma membrane ATPase activity glucuronoside metabolic process brush border membrane riboflavin transmembrane transporter activity riboflavin transmembrane transporter activity riboflavin transport riboflavin transport ATPase-coupled transmembrane transporter activity identical protein binding protein homodimerization activity amide transmembrane transporter activity xenobiotic transmembrane transporter activity membrane raft urate metabolic process transmembrane transport embryonic process involved in female pregnancy protein-containing complex assembly transepithelial transport urate salt excretion external side of apical plasma membrane export across plasma membrane negative regulation of intestinal absorption cellular detoxification xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic transport across blood-brain barrier	02010 04976
TC1500002223.mm.2	Lima1	LIM domain and actin binding 1	15	-99778467, -99778467	NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490	65970	51	stress fiber ruffle actin binding actin monomer binding protein binding cytoplasm cytosol cytoskeleton plasma membrane plasma membrane brush border focal adhesion lipid metabolic process steroid metabolic process cholesterol metabolic process actin cytoskeleton actin cytoskeleton actin cytoskeleton membrane cell migration intestinal cholesterol absorption negative regulation of actin filament depolymerization brush border membrane ruffle organization ruffle organization cleavage furrow cholesterol homeostasis cell projection metal ion binding actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly
TC1000002493.mm.2	Gamt	guanidinoacetate methyltransferase	10	-80258150	NM_010255, BC049233 NM_010255, BC049233	14431	39	nucleus cytoplasm cytosol creatine biosynthetic process creatine biosynthetic process creatine biosynthetic process spermatogenesis methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity animal organ morphogenesis transferase activity guanidinoacetate N-methyltransferase activity guanidinoacetate N-methyltransferase activity methylation regulation of multicellular organism growth identical protein binding cell projection S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process	00260 00330 01100
TC1200002411.mm.2	Ckb	creatine kinase, brain	12	-111669354	NM_021273, BC015271, BC106109 NM_021273, BC015271, BC106109 NM_021273, BC015271, BC106109	12709	78	nucleotide binding catalytic activity creatine kinase activity creatine kinase activity protein binding ATP binding extracellular space nucleus cytoplasm mitochondrion cytosol kinase activity transferase activity transferase activity, transferring phosphorus-containing groups dendrite cellular chloride ion homeostasis ubiquitin protein ligase binding neuronal cell body myelin sheath phosphocreatine biosynthetic process	00330 01100
TC1400001174.mm.2	Uchl3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	14	101653966	NM_016723, BC048481 NM_016723, BC048481	50933	43	thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity intracellular anatomical structure nucleoplasm cytoplasm cytosol proteolysis ubiquitin-dependent protein catabolic process adult walking behavior peptidase activity peptidase activity cysteine-type peptidase activity protein deubiquitination protein deubiquitination protein deubiquitination protein deubiquitination hydrolase activity protein catabolic process protein catabolic process cellular response to insulin stimulus eating behavior ubiquitin binding positive regulation of fat cell differentiation retina development in camera-type eye ubiquitinyl hydrolase activity
TC0200001951.mm.2	Slc20a1	solute carrier family 20, member 1	2	129198772, 129207095, 129198772	NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085	20515	63	inorganic phosphate transmembrane transporter activity high-affinity inorganic phosphate:sodium symporter activity plasma membrane integral component of plasma membrane sodium ion transport phosphate ion transport symporter activity membrane integral component of membrane biomineral tissue development phosphate ion transmembrane transport
TC0700000798.mm.2					NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896			molecular_function cellular_component biological_process
TC0300001181.mm.2	Dph5	diphthamide biosynthesis 5	3	115888182	NM_027193, BC060372 NM_027193, BC060372	69740	16	diphthine synthase activity cellular_component methyltransferase activity transferase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine methylation
TC0800002153.mm.2	Ankrd37	ankyrin repeat domain 37	8	-45996907	NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377	654824	14	protein binding nucleus nucleoplasm cytoplasm mitochondrion cytosol biological_process
TC0800001258.mm.2	Utp4	UTP4 small subunit processome component	8	106893639	NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113	21771	28	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleus chromosome nucleolus regulation of transcription, DNA-templated rRNA processing maturation of SSU-rRNA 90S preribosome small-subunit processome t-UTP complex t-UTP complex ribosome biogenesis	03008
TC0800001493.mm.2	Cdt1	chromatin licensing and DNA replication factor 1	8	122568014	NM_026014, BC048076 NM_026014, BC048076	67177	45	DNA replication checkpoint DNA replication checkpoint DNA replication checkpoint mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore DNA binding DNA binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm chromosome DNA replication cell cycle chromosome segregation nuclear body regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation positive regulation of protein-containing complex assembly regulation of chromosome organization regulation of nuclear cell cycle DNA replication positive regulation of chromatin binding positive regulation of DNA replication cell division attachment of mitotic spindle microtubules to kinetochore kinetochore organization DNA polymerase binding DNA replication preinitiation complex assembly DNA replication preinitiation complex assembly response to sorbitol deactivation of mitotic spindle assembly checkpoint regulation of DNA replication origin binding negative regulation of protein localization to kinetochore positive regulation of protein localization to kinetochore positive regulation of DNA-dependent DNA replication
TC0100001244.mm.2	Ptpn7	protein tyrosine phosphatase, non-receptor type 7	1	135133308, 135132699	NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190	320139	17	phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity cytoplasm cytosol cytoskeleton protein dephosphorylation protein dephosphorylation cytoplasmic side of plasma membrane microtubule cytoskeleton dephosphorylation hydrolase activity phosphatase activity mitotic spindle	04010
TC0900001979.mm.2	Aplp2	amyloid beta (A4) precursor-like protein 2	9	-31149556	NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396	11804	111	suckling behavior DNA binding protein binding nucleus plasma membrane cellular copper ion homeostasis regulation of epidermal growth factor-activated receptor activity mating behavior locomotory behavior heparin binding cholesterol metabolic process embryo development membrane integral component of membrane extracellular matrix organization forebrain development midbrain development identical protein binding regulation of protein binding metal ion binding transition metal ion binding neuromuscular process controlling balance
TC1300001634.mm.2	H2ac8	H2A clustered histone 8	13	-23570662	NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498	319166	12	DNA binding nucleus chromatin silencing enzyme binding	05322
TC0X00003361.mm.2	Prps2	phosphoribosyl pyrophosphate synthetase 2	X	-167346319	NM_026662, BC024942 NM_026662, BC024942	110639	23	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex identical protein binding ADP binding cellular biosynthetic process metal ion binding	00030 00230 01100
TC1700002414.mm.2	Rab31	RAB31, member RAS oncogene family	17	-65651725	NM_133685, BC013063 NM_133685, BC013063	106572	25	nucleotide binding phagocytic cup GTPase activity protein binding GTP binding cytoplasm endosome early endosome late endosome Golgi apparatus trans-Golgi network intracellular protein transport endomembrane system membrane GDP binding cytoplasmic vesicle receptor internalization trans-Golgi network membrane trans-Golgi network membrane cellular response to insulin stimulus early phagosome membrane Golgi to plasma membrane protein transport Golgi to plasma membrane protein transport regulated exocytosis phagocytic vesicle Golgi vesicle transport positive regulation of phagocytosis, engulfment phagosome maturation	04144
TC1600001308.mm.2	Ranbp1	RAN binding protein 1	16	-18239978	NM_011239, BC061140 NM_011239, BC061140	19385	59	GDP-dissociation inhibitor activity GTPase activator activity nucleus nuclear pore cytoplasm cytoplasm cytoplasm centrosome centrosome cytosol spindle organization positive regulation of neuron projection development plasma membrane bounded cell projection cytoplasm positive regulation of mitotic centrosome separation positive regulation of mitotic centrosome separation intracellular transport cellular response to leptomycin B axon cytoplasm
TC0X00001272.mm.2					NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719			nucleic acid binding RNA binding mRNA binding nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA polyadenylation mRNA processing nuclear body mRNA 3'-end processing cleavage body pre-mRNA cleavage required for polyadenylation
TC0500002420.mm.2	Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)	5	-53107082	NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916	231238	18	molecular_function nucleoplasm biological_process membrane integral component of membrane
TC0500001648.mm.2	Nxpe5	neurexophilin and PC-esterase domain family, member 5	5	138225903	NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195	381680	10	molecular_function cellular_component biological_process
TC0400003349.mm.2	Mmachc	methylmalonic aciduria cblC type, with homocystinuria	4	-116702433	NM_025962, BC054756 NM_025962, BC054756	67096	21	cytoplasm cytoplasm mitochondrion glutathione metabolic process cobalamin metabolic process cobalamin metabolic process oxidoreductase activity transferase activity cobalamin binding demethylase activity demethylase activity cyanocobalamin reductase (cyanide-eliminating) activity cyanocobalamin reductase (cyanide-eliminating) activity protein homodimerization activity glutathione binding demethylation FAD binding FAD binding	04977
TC0800003249.mm.2	Emc8	ER membrane protein complex subunit 8	8	-120653913	NM_010926, BC009103 NM_010926, BC009103	18117	21	cytoplasm mitochondrion cytosol membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane EMC complex EMC complex
TC0100003204.mm.2	Rgs2	regulator of G-protein signaling 2	1	-143999337	NM_009061, BC023001 NM_009061, BC023001	19735	111	G-protein alpha-subunit binding GTPase activator activity GTPase activator activity protein binding nucleus nucleus cytoplasm cytosol cytosol plasma membrane plasma membrane regulation of translation cell cycle G protein-coupled receptor signaling pathway spermatogenesis regulation of G protein-coupled receptor signaling pathway cytoplasmic side of plasma membrane cytoplasmic side of plasma membrane negative regulation of signal transduction negative regulation of phospholipase activity negative regulation of cardiac muscle hypertrophy positive regulation of neuron projection development membrane negative regulation of translation neuron projection negative regulation of MAP kinase activity negative regulation of cAMP-mediated signaling negative regulation of G protein-coupled receptor signaling pathway negative regulation of G protein-coupled receptor signaling pathway beta-tubulin binding brown fat cell differentiation relaxation of cardiac muscle relaxation of vascular associated smooth muscle positive regulation of cardiac muscle contraction negative regulation of cell growth involved in cardiac muscle cell development negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process negative regulation of glycine import across plasma membrane
TC0800000972.mm.2					NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661			DNA catabolic process, endonucleolytic nuclease activity endonuclease activity endodeoxyribonuclease activity deoxyribonuclease II activity deoxyribonuclease II activity lysosome DNA metabolic process DNA catabolic process apoptotic DNA fragmentation apoptotic process multicellular organism development hydrolase activity erythrocyte differentiation regulation of immune response
TC0900001302.mm.2	Topbp1	topoisomerase (DNA) II binding protein 1	9	103305326	NM_176979, BC049797 NM_176979, BC049797	235559	50	condensed nuclear chromosome male germ cell nucleus DNA binding nucleus nucleoplasm chromosome chromosome cytoplasm cytoskeleton plasma membrane DNA replication initiation DNA repair cellular response to DNA damage stimulus mitotic G2 DNA damage checkpoint reciprocal meiotic recombination response to ionizing radiation actin cytoskeleton nuclear body PML body mitotic DNA replication checkpoint identical protein binding intracellular membrane-bounded organelle
TC0800001541.mm.2	Urb2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	8	124021496	NM_001029876, BC151125 NM_001029876, BC151125	382038	13	molecular_function nucleolus nucleolus aggresome midbody ribosome biogenesis
TC0700001871.mm.2	Fus	fused in sarcoma	7	127967478	NM_139149, BC040827, BC058247 NM_139149, BC040827, BC058247 NM_139149, BC040827, BC058247	233908	143	transcription coregulator activity RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm polysome RNA splicing gene expression gene expression estrogen receptor binding dendrite myosin V binding ionotropic glutamate receptor binding neuronal cell body dendritic spine perikaryon dendritic spine head retinoid X receptor binding thyroid hormone receptor binding mRNA stabilization perinuclear region of cytoplasm cellular response to calcium ion
TC1500001585.mm.2	Mtss1	MTSS I-BAR domain containing 1	15	-58941233	NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131	211401	51	in utero embryonic development actin binding actin monomer binding signaling receptor binding protein binding cytoplasm cytoskeleton adherens junction plasma membrane organization actin filament organization nervous system development muscle organ development magnesium ion homeostasis actin cytoskeleton actin cytoskeleton organization actin filament polymerization bone mineralization positive regulation of actin filament bundle assembly adherens junction maintenance identical protein binding identical protein binding negative regulation of epithelial cell proliferation actin filament binding renal tubule morphogenesis cellular response to fluid shear stress glomerulus morphogenesis nephron tubule epithelial cell differentiation metanephric tubule development epithelial cell proliferation involved in renal tubule morphogenesis
TC0800001031.mm.2	Adcy7	adenylate cyclase 7	8	88282991, 88289065, 88272402, 88294203	NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833	11513	30	nucleotide binding regulation of adaptive immune response adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane integral component of plasma membrane cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity cyclic nucleotide biosynthetic process membrane integral component of membrane lyase activity phosphorus-oxygen lyase activity intracellular signal transduction metal ion binding cellular response to lithium ion cellular response to ethanol negative regulation of cytokine production involved in inflammatory response	00230 04020 04062 04114 04270 04540 04912 04914 04916 04970 04971 04972 04976 05414
TC1100002069.mm.2	Metrnl	meteorin, glial cell differentiation regulator-like	11	121702426	NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646	210029	27	hormone activity hormone activity extracellular region extracellular space extracellular space extracellular space response to cold response to muscle activity fat cell differentiation negative regulation of inflammatory response brown fat cell differentiation positive regulation of brown fat cell differentiation positive regulation of brown fat cell differentiation energy homeostasis energy homeostasis
TC1900000312.mm.2	Prune2	prune homolog 2	19	16956117	NM_181348, BC095978 NM_181348, BC095978	353211	29	exopolyphosphatase activity cytoplasm polyphosphate catabolic process apoptotic process pyrophosphatase activity
TC1300002269.mm.2	Mtrr	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	13	-68560779, -68560779	NM_172480, BC025942 NM_172480, BC025942	210009	26	NADPH-hemoprotein reductase activity nucleoplasm cytoplasm cytosol cytosol DNA methylation cellular amino acid biosynthetic process methionine biosynthetic process methionine biosynthetic process methionine biosynthetic process FMN binding FMN binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [methionine synthase] reductase activity [methionine synthase] reductase activity [methionine synthase] reductase activity S-adenosylmethionine cycle homocysteine catabolic process intermediate filament cytoskeleton folic acid metabolic process folic acid metabolic process flavin adenine dinucleotide binding flavin adenine dinucleotide binding homocysteine metabolic process homocysteine metabolic process protein stabilization NADPH binding FAD binding negative regulation of cystathionine beta-synthase activity
TC1400001783.mm.2	Tspan14	tetraspanin 14	14	-40906426, -40906426	NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574	52588	24	plasma membrane integral component of plasma membrane cell surface membrane integral component of membrane enzyme binding enzyme binding positive regulation of Notch signaling pathway protein maturation protein maturation protein localization to plasma membrane tetraspanin-enriched microdomain
TC0900001101.mm.2	Ttk	Ttk protein kinase	9	83834688, 83834688	NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851	22137	34	nucleotide binding kinetochore kinetochore protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm spindle protein phosphorylation chromosome segregation mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint membrane kinase activity phosphorylation female meiosis chromosome segregation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation meiotic spindle assembly checkpoint meiotic spindle assembly checkpoint protein localization to kinetochore protein localization to kinetochore protein localization to chromosome identical protein binding kinetochore binding protein autophosphorylation chromosome separation meiotic prometaphase I protein localization to meiotic spindle midzone	04110
TC0500001894.mm.2	Cyp51	cytochrome P450, family 51	5	-4080673	NM_020010, BC031813 NM_020010, BC031813	13121	55	monooxygenase activity iron ion binding endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process sterol 14-demethylase activity sterol 14-demethylase activity membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding cholesterol biosynthetic process via 24,25-dihydrolanosterol negative regulation of protein catabolic process intracellular membrane-bounded organelle metal ion binding negative regulation of protein secretion negative regulation of amyloid-beta clearance	00100 01100
TC0300003221.mm.2	Wdr77	WD repeat domain 77	3	105959497	NM_027432, BC005755 NM_027432, BC005755	70465	39	protein binding nucleus nucleoplasm nucleoplasm cytoplasm Golgi apparatus cytosol cytosol regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II pole plasm assembly positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation methyl-CpG binding methyl-CpG binding nuclear receptor coactivator activity nuclear receptor coactivator activity methylosome methylosome pole plasm secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development negative regulation of epithelial cell proliferation involved in prostate gland development negative regulation of epithelial cell proliferation involved in prostate gland development
TC1800001087.mm.2	Tpgs2	tubulin polyglutamylase complex subunit 2	18	-25136038, -25127222, -25136038	NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777	66648	19	molecular_function cellular_component cytoplasm cytosol cytoskeleton microtubule biological_process protein polyglutamylation protein polyglutamylation
TC0100003478.mm.2	Uck2	uridine-cytidine kinase 2	1	-167226083	NM_030724, BC023789 NM_030724, BC023789	80914	24	nucleotide binding uridine kinase activity protein binding ATP binding cytoplasm cytosol cytosol CMP salvage phosphorylation transferase activity nucleoside kinase activity identical protein binding intracellular membrane-bounded organelle UMP salvage	00240 00983 01100
TC0700004363.mm.2	Rgs10	regulator of G-protein signalling 10	7	-128373624	NM_026418, BC109178 NM_026418, BC109178	67865	37	G-protein alpha-subunit binding GTPase activator activity protein binding nucleus cytoplasm cytosol G protein-coupled acetylcholine receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction neuronal cell body dendritic spine positive regulation of GTPase activity axon terminus
TC1100001973.mm.2	Birc5	baculoviral IAP repeat-containing 5	11	117849236	NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702	11799	215	G2/M transition of mitotic cell cycle microtubule cytoskeleton organization nuclear chromosome mitotic cytokinesis chromosome, centromeric region kinetochore condensed chromosome kinetochore cysteine-type endopeptidase inhibitor activity protein binding nucleus nucleus chromosome cytoplasm cytoplasm cytoplasm centriole cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cytoplasmic microtubule protein phosphorylation apoptotic process cell cycle chromosome segregation mitotic spindle assembly checkpoint regulation of mitotic cell cycle microtubule binding zinc ion binding embryo development negative regulation of peptidase activity tubulin binding apical plasma membrane enzyme binding peptidase inhibitor activity midbody interphase microtubule organizing center small GTPase binding protein-containing complex localization positive regulation of exit from mitosis chromosome passenger complex protein-containing complex identical protein binding protein homodimerization activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process positive regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of mitotic cell cycle metal ion binding protein heterodimerization activity chaperone binding cell division establishment of chromosome localization regulation of cell cycle regulation of insulin secretion involved in cellular response to glucose stimulus regulation of type B pancreatic cell proliferation	05200 05210
TC0900001652.mm.2	Kif15	kinesin family member 15	9	122951080	NM_010620, BC060710 NM_010620, BC060710	209737	26	nucleotide binding microtubule motor activity ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding ATPase activity
TC1500002217.mm.2	Racgap1	Rac GTPase-activating protein 1	15	-99620495	NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715	26934	52	mitotic cytokinesis actomyosin contractile ring assembly GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleoplasm cytoplasm spindle cytoskeleton plasma membrane ion transport cell cycle signal transduction multicellular organism development spermatogenesis neuroblast proliferation microtubule binding sulfate transport lipid binding membrane protein kinase binding cell differentiation midbody extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cleavage furrow positive regulation of cytokinesis intracellular signal transduction alpha-tubulin binding gamma-tubulin binding regulation of embryonic development metal ion binding beta-tubulin binding spindle midzone mitotic spindle midzone assembly cell division regulation of attachment of spindle microtubules to kinetochore mitotic spindle centralspindlin complex
TC0600003373.mm.2	Recql	RecQ protein-like	6	-142350341, -142361375, -142356946, -142361375	NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735	19691	21	nucleotide binding double-strand break repair via homologous recombination DNA strand renaturation nucleic acid binding DNA binding DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome cytoplasm DNA unwinding involved in DNA replication DNA repair DNA recombination four-way junction helicase activity hydrolase activity DNA duplex unwinding annealing helicase activity annealing helicase activity 3'-5' DNA helicase activity
TC1200000647.mm.2	Prkch	protein kinase C, eta	12	73584795	NM_008856, BC031121 NM_008856, BC031121	18755	43	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-independent protein kinase C activity protein binding ATP binding cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction protein phosphorylation positive regulation of macrophage derived foam cell differentiation membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation enzyme binding cell differentiation small GTPase binding negative regulation of glial cell apoptotic process intracellular signal transduction positive regulation of keratinocyte differentiation metal ion binding positive regulation of B cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity positive regulation of glial cell proliferation protein kinase C signaling regulation of bicellular tight junction assembly	04270 04530
TC0600000788.mm.2	Serbp1	serpine1 mRNA binding protein 1	6	67266978	NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502	66870	38	RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleus cytoplasm cytoplasm cytosol PML body organization SUMO binding
TC1300001353.mm.2	Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	13	119690350	NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317	208715	44	catalytic activity hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity cytoplasm cytosol cytosol acetyl-CoA metabolic process lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process farnesyl diphosphate biosynthetic process, mevalonate pathway response to purine-containing compound sterol biosynthetic process transferase activity isomerase activity small molecule binding protein homodimerization activity organic acid binding cellular response to low-density lipoprotein particle stimulus	00072 00280 00650 00900 01100
TC0300002203.mm.2	Tmem144	transmembrane protein 144	3	-79812563, -79812563, -79812563, -79812563	NM_027495, BC018493 NM_027495, BC018493	70652	11	molecular_function cellular_component biological_process carbohydrate transmembrane transporter activity membrane integral component of membrane carbohydrate transmembrane transport
TC1500000053.mm.2	Nup155	nucleoporin 155	15	8109312	NM_133227, BC050919 NM_133227, BC050919	170762	28	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear envelope nuclear pore cytoplasm RNA export from nucleus mRNA export from nucleus protein import into nucleus protein import into nucleus nucleocytoplasmic transport nuclear envelope organization protein transport membrane structural constituent of nuclear pore nuclear membrane protein localization to nuclear inner membrane nuclear pore inner ring mRNA transport atrial cardiac muscle cell action potential	03013
TC0300000586.mm.2	Nmd3	NMD3 ribosome export adaptor	3	69722054	NM_133787, BC003842, NMD3(S NM_133787, BC003842, NMD3(S NM_133787, BC003842, NMD3(S	97112	20	ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm protein transport protein-macromolecule adaptor activity positive regulation of protein binding ribosomal large subunit binding ribosomal large subunit binding positive regulation of RNA biosynthetic process positive regulation of protein localization to nucleolus	03008 03013
TC0800003233.mm.2	Trmt1	tRNA methyltransferase 1	8	84689283, 84689246, 84686323	NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404	212528	21	tRNA binding tRNA N2-guanine methylation RNA binding tRNA (guanine-N2-)-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity nucleus tRNA processing methyltransferase activity transferase activity methylation metal ion binding
TC1800000704.mm.2	Tubb6	tubulin, beta 6 class V	18	67390730	NM_026473, BC008225 NM_026473, BC008225	67951	38	nucleotide binding microtubule cytoskeleton organization mitotic cell cycle GTPase activity structural constituent of cytoskeleton GTP binding cytoplasm cytoskeleton microtubule microtubule microtubule-based process	04145 04540
TC0800000987.mm.2	Orc6	origin recognition complex, subunit 6	8	85299631	NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739	56452	21	origin recognition complex fibrillar center DNA binding nucleus nucleoplasm nuclear origin of replication recognition complex DNA replication DNA-dependent DNA replication DNA replication initiation negative regulation of cell division	04110
TC0500001865.mm.2	Brca2	breast cancer 2, early onset	5	150522620	NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649	12190	178	telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region lateral element oocyte maturation inner cell mass cell proliferation protease binding DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton DNA repair nucleotide-excision repair double-strand break repair double-strand break repair DNA recombination regulation of transcription, DNA-templated cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle male meiosis I male meiosis I spermatogenesis spermatogenesis brain development cell aging protein C-terminus binding cell population proliferation female gonad development intrinsic apoptotic signaling pathway in response to DNA damage response to X-ray response to UV-C response to gamma radiation H3 histone acetyltransferase activity H4 histone acetyltransferase activity hemopoiesis secretory granule mammary gland development homologous chromosome orientation involved in meiotic metaphase I plate congression regulation of cytokinesis protein-containing complex BRCA2-MAGE-D1 complex negative regulation of mammary gland epithelial cell proliferation multicellular organism growth intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding chordate embryonic development gamma-tubulin binding histone H3 acetylation histone H4 acetylation positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle replication fork protection chromosome organization centrosome duplication establishment of protein localization to telomere establishment of protein localization to telomere mitotic recombination-dependent replication fork processing	03440 05200 05212
TC1100004296.mm.2	Nme1	NME/NM23 nucleoside diphosphate kinase 1	11	-93958924, -93958924	NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23	18102	75	nucleotide binding magnesium ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding negative regulation of myeloid leukocyte differentiation single-stranded DNA binding deoxyribonuclease activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding GTP binding nucleus cytoplasm mitochondrion mitochondrial outer membrane centrosome cytosol intermediate filament nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process endocytosis nervous system development lactation nucleotide metabolic process negative regulation of gene expression positive regulation of neuron projection development membrane kinase activity phosphorylation transferase activity intermediate filament binding enzyme binding protein kinase binding cell differentiation mammary gland development ruffle membrane identical protein binding gamma-tubulin binding ribosomal small subunit binding myelin sheath positive regulation of DNA binding metal ion binding perinuclear region of cytoplasm positive regulation of epithelial cell proliferation	00230 00240 01100
TC0700004451.mm.2	Mki67	antigen identified by monoclonal antibody Ki 67	7	-135689787	NM_001081117	17345	1917	nucleotide binding chromosome, centromeric region condensed chromosome condensed chromosome DNA binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm cell cycle regulation of mitotic nuclear division protein C-terminus binding cell population proliferation nuclear body meiotic cell cycle regulation of chromosome segregation hepatocyte proliferation regulation of chromatin organization cholangiocyte proliferation
TC1400002057.mm.2	Prmt5	protein arginine N-methyltransferase 5	14	-54507181	NM_013768, BC023905 NM_013768, BC023905	27374	104	negative regulation of transcription by RNA polymerase II spliceosomal snRNP assembly p53 binding chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm Golgi apparatus cytosol cytosol chromatin organization DNA-templated transcription, termination regulation of transcription, DNA-templated protein methylation methyltransferase activity methyl-CpG binding histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation methylation circadian regulation of gene expression protein-containing complex methylosome histone arginine methylation histone methyltransferase complex histone methyltransferase complex protein-arginine omega-N symmetric methyltransferase activity peptidyl-arginine N-methylation endothelial cell activation identical protein binding ribonucleoprotein complex binding histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) regulation of DNA methylation protein-containing complex binding negative regulation of cell differentiation protein heterodimerization activity rhythmic process positive regulation of oligodendrocyte differentiation regulation of ERK1 and ERK2 cascade E-box binding Golgi ribbon formation positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	03013
TC0800000146.mm.2	Cln8	CLN8 transmembrane ER and ERGIC protein	8	14888535	NM_012000, BC021625 NM_012000, BC021625	26889	85	age-dependent response to oxidative stress protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment phospholipid metabolic process phospholipid metabolic process phospholipid metabolic process ceramide metabolic process mitochondrial membrane organization lysosome organization nervous system development nervous system development visual perception adult walking behavior cholesterol metabolic process associative learning adult locomotory behavior regulation of cell size membrane integral component of membrane spinal cord motor neuron differentiation somatic motor neuron differentiation social behavior negative regulation of apoptotic process cellular protein catabolic process cellular macromolecule catabolic process cellular protein metabolic process photoreceptor cell maintenance musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate reuptake lipid homeostasis retina development in camera-type eye neurofilament cytoskeleton organization ceramide binding ceramide binding
TC0400002457.mm.2	Nol6	nucleolar protein family 6 (RNA-associated)	4	-41114426	NM_139236, BC059820 NM_139236, BC059820	230082	24	condensed nuclear chromosome RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus mitochondrion rRNA processing tRNA export from nucleus small-subunit processome CURI complex UTP-C complex	03008
TC1000003152.mm.2	Pa2g4	proliferation-associated 2G4	10	-128557765	NM_011119, BC046532 NM_011119, BC046532	18813	52	nucleic acid binding transcription corepressor activity RNA binding nucleus nucleolus cytoplasm rRNA processing regulation of translation ubiquitin protein ligase binding negative regulation of apoptotic process positive regulation of cell differentiation negative regulation of transcription, DNA-templated ribonucleoprotein complex
TC1300000033.mm.2	Pitrm1	pitrilysin metallepetidase 1	13	6548156, 6548156	NM_145131, BC006917 NM_145131, BC006917	69617	28	catalytic activity metalloendopeptidase activity metalloendopeptidase activity mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix proteolysis peptidase activity metallopeptidase activity zinc ion binding protein processing hydrolase activity metal ion binding
TC0800003236.mm.2	Usp10	ubiquitin specific peptidase 10	8	119910359	NM_009462, BC007134 NM_009462, BC007134	22224	38	p53 binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity nucleus nucleus nucleoplasm cytoplasm endosome early endosome early endosome cytosol cytosol DNA repair ubiquitin-dependent protein catabolic process autophagy cellular response to DNA damage stimulus peptidase activity cysteine-type peptidase activity regulation of autophagy regulation of autophagy protein deubiquitination protein deubiquitination hydrolase activity DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator protein-containing complex negative regulation of I-kappaB kinase/NF-kappaB signaling ion channel binding intermediate filament cytoskeleton cellular response to interleukin-1
TC0400002222.mm.2	Cibar1	CBY1 interacting BAR domain containing 1	4	-12153141	NM_026558, BC020162 NM_026558, BC020162	68099	19	protein binding phospholipid binding nucleus cytoplasm mitochondrial inner membrane centriole cytoskeleton cilium inner mitochondrial membrane organization cell projection organization limb morphogenesis limb morphogenesis ciliary transition zone ciliary basal body cell projection positive regulation of smoothened signaling pathway cilium assembly cilium assembly membrane organization ciliary base
TC0600000648.mm.2	Chn2	chimerin 2	6	54039931, 54272821, 54269155, 54264857	NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060	69993	32	GTPase activator activity GTPase activator activity signal transduction membrane intracellular signal transduction regulation of GTPase activity synapse metal ion binding
TC1400001314.mm.2	Ipo5	importin 5	14	120915846, 120911193	NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814	70572	40	protein binding nucleus nucleus cytoplasm cytoplasm protein import into nucleus NLS-bearing protein import into nucleus ribosomal protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding positive regulation of protein import into nucleus nuclear import signal receptor activity nuclear import signal receptor activity cellular response to amino acid stimulus
TC1700000777.mm.2	Olfr111	olfactory receptor 111	17	37529956	NM_001005485, BC139116, BC139117 NM_001005485, BC139116, BC139117 NM_001005485, BC139116, BC139117	545205	6	olfactory receptor activity G protein-coupled receptor signaling pathway sensory perception of smell integral component of membrane
TC1900000212.mm.2	Prpf19	pre-mRNA processing factor 19	19	10898644, 10895230	NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070	28000	38	protein polyubiquitination spliceosomal tri-snRNP complex assembly spliceosomal complex assembly generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome Prp19 complex Prp19 complex inner cell mass cell proliferation ubiquitin-protein transferase activity protein binding nucleus nucleus DNA replication factor A complex spliceosomal complex cytoplasm cytoplasm lipid droplet cytoskeleton DNA repair double-strand break repair via nonhomologous end joining mRNA processing cellular response to DNA damage stimulus RNA splicing lipid biosynthetic process proteasomal protein catabolic process proteasomal protein catabolic process nuclear speck transferase activity ubiquitin-ubiquitin ligase activity cellular protein localization site of double-strand break identical protein binding negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of mRNA splicing, via spliceosome positive regulation of astrocyte differentiation positive regulation of astrocyte differentiation ubiquitin protein ligase activity protein K63-linked ubiquitination U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome signal transduction involved in DNA damage checkpoint	03040 04120
TC0100001858.mm.2	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	1	191821472	NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576	18005	48	mitotic sister chromatid segregation nucleotide binding chromosome, centromeric region kinetochore condensed nuclear chromosome spindle pole blastocyst development protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cytoskeleton microtubule protein phosphorylation protein phosphorylation cell cycle chromosome segregation chromosome segregation chromosome segregation kinase activity phosphorylation transferase activity protein phosphatase binding midbody positive regulation of telomere maintenance via telomerase protein-containing complex negative regulation of DNA binding regulation of mitotic centrosome separation protein autophosphorylation metal ion binding centrosome separation cell division meiotic cell cycle positive regulation of telomerase activity regulation of attachment of spindle microtubules to kinetochore mitotic spindle assembly negative regulation of centriole-centriole cohesion positive regulation of telomere capping
TC0400003633.mm.2	Nkain1	Na+/K+ transporting ATPase interacting 1	4	-130530130	NM_025998, BC116391 NM_025998, BC116391	67149	18	regulation of sodium ion transport plasma membrane membrane integral component of membrane ATPase binding
TC0100003280.mm.2	Npl	N-acetylneuraminate pyruvate lyase	1	-153503015	NM_028749, BC022734 NM_028749, BC022734	74091	23	catalytic activity cellular_component cytoplasm carbohydrate metabolic process N-acetylneuraminate lyase activity N-acetylneuraminate lyase activity lyase activity N-acetylneuraminate catabolic process identical protein binding	00520
TC1800001083.mm.2	Slc39a6	solute carrier family 39 (metal ion transporter), member 6	18	-24579880	NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012	106957	27	zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity endoplasmic reticulum plasma membrane integral component of plasma membrane integral component of plasma membrane ion transport zinc ion transport cellular zinc ion homeostasis cellular zinc ion homeostasis membrane integral component of membrane metal ion transport lamellipodium membrane metal ion transmembrane transporter activity transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane
TC0100002308.mm.2	Myo1b	myosin IB	1	-51749757	NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786	17912	41	microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding calmodulin binding ATP binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytoplasm early endosome actin filament plasma membrane plasma membrane microvillus brush border brush border brush border post-Golgi vesicle-mediated transport actin filament organization actin filament organization endosome membrane actin cytoskeleton myosin complex actin filament-based movement vesicle transport along actin filament filopodium actin-dependent ATPase activity actin-dependent ATPase activity vesicle trans-Golgi network membrane transferrin transport apical part of cell perinuclear region of cytoplasm actin filament binding actin filament binding actin filament bundle assembly cell periphery
TC1300001751.mm.2	Gmds	GDP-mannose 4, 6-dehydratase	13	-31819585	NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502	218138	21	cytoplasm GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process	00051 00520 01100
TC0900000505.mm.2	H2ax	H2A.X variant histone	9	44334714	NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A,	15270	476	double-strand break repair via homologous recombination chromosome, telomeric region chromatin nucleosome condensed nuclear chromosome male germ cell nucleus XY body DNA binding damaged DNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome centrosome DNA repair DNA repair DNA recombination chromatin silencing cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle spermatogenesis nuclear speck enzyme binding site of double-strand break site of double-strand break histone binding protein heterodimerization activity meiotic cell cycle cellular response to gamma radiation site of DNA damage	05322
TC1500000736.mm.2	Xrcc6	X-ray repair complementing defective repair in Chinese hamster cells 6	15	82016368	NM_010247, BC031422 NM_010247, BC031422	14375	137	nucleotide binding telomere maintenance transcription regulatory region sequence-specific DNA binding activation of innate immune response immune system process DNA binding DNA helicase activity damaged DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded telomeric DNA binding catalytic activity helicase activity protein binding ATP binding nucleus nucleus nucleoplasm transcription regulator complex chromosome nucleolus cytoplasm cytoplasm DNA repair double-strand break repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining DNA recombination cellular response to DNA damage stimulus protein C-terminus binding DNA-dependent ATPase activity metabolic process response to ionizing radiation hydrolase activity lyase activity cyclin binding protein-containing complex protein-DNA complex V(D)J recombination telomeric DNA binding Ku70:Ku80 complex Ku70:Ku80 complex protein-containing complex binding DNA end binding innate immune response positive regulation of lymphocyte differentiation positive regulation of protein kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of smooth muscle cell proliferation positive regulation of neurogenesis 5'-deoxyribose-5-phosphate lyase activity nonhomologous end joining complex cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to gamma radiation cellular response to X-ray cellular response to X-ray double-strand break repair via classical nonhomologous end joining	03450
TC1800000063.mm.2	Colec12	collectin sub-family member 12	18	9707647	NM_130449, BC057936 NM_130449, BC057936	140792	19	scavenger receptor activity collagen trimer phagocytosis, recognition phagocytosis, recognition immune response membrane integral component of membrane low-density lipoprotein particle binding low-density lipoprotein particle binding carbohydrate binding toll-like receptor 3 signaling pathway signaling receptor activity pattern recognition receptor activity pattern recognition receptor activity defense response to bacterium metal ion binding positive regulation of cell adhesion molecule production collagen-containing extracellular matrix	04145
TC0500002580.mm.2	Tec	tec protein tyrosine kinase	5	-72755717	NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884	21682	74	nucleotide binding adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane cell-cell junction protein phosphorylation integrin-mediated signaling pathway integrin-mediated signaling pathway lipid binding regulation of platelet activation regulation of platelet activation membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation intracellular signal transduction peptidyl-tyrosine autophosphorylation peptidyl-tyrosine autophosphorylation tissue regeneration metal ion binding positive regulation of peptidyl-tyrosine phosphorylation T cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway	04380 04660
TC0300000714.mm.2	Iqgap3	IQ motif containing GTPase activating protein 3	3	88082050	NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704	404710	20	G1/S transition of mitotic cell cycle activation of MAPK activity positive regulation of protein phosphorylation GTPase activator activity protein binding calmodulin binding calmodulin binding cytoplasm cytoplasm cell-cell junction Ras protein signal transduction regulation of cell size positive regulation of gene expression negative regulation of gene expression lateral plasma membrane small GTPase binding regulation of actin cytoskeleton organization positive regulation of mammary gland epithelial cell proliferation actin filament binding ERK1 and ERK2 cascade myosin VI light chain binding cellular response to organic substance	04810
TC1300000173.mm.2	H2ac13	H2A clustered histone 13	13	21716411	NM_178182, BC099406 NM_178182, BC099406	319191	16	DNA binding nucleus chromatin silencing negative regulation of cell population proliferation	05322
TC1800001138.mm.2	Stard4	StAR-related lipid transfer (START) domain containing 4	18	-33199137	NM_133774, BC005642 NM_133774, BC005642	170459	24	cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum cytosol cytosol lipid transport lipid binding positive regulation of cholesterol esterification cholesterol transport involved in cholesterol storage cholesterol transport involved in cholesterol storage cholesterol binding cholesterol binding cholesterol binding cytoplasmic vesicle intracellular cholesterol transport intracellular cholesterol transport cholesterol esterification cholesterol import cholesterol import positive regulation of bile acid biosynthetic process cholesterol transfer activity cholesterol transfer activity
TC0800001094.mm.2	Mt2	metallothionein 2	8	94172617	NM_008630, BC031758 NM_008630, BC031758	17750	217	nucleus cytoplasm cytosol cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding response to bacterium detoxification of copper ion detoxification of copper ion metal ion binding cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion
TC0800003059.mm.2	Slc7a5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	8	-121881145	NM_011404, BC026131 NM_011404, BC026131	20539	56	amino acid transmembrane transport lysosome cytosol plasma membrane amino acid transport basal plasma membrane negative regulation of gene expression amino acid transmembrane transporter activity aromatic amino acid transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-leucine transmembrane transporter activity L-tryptophan transmembrane transporter activity thyroid hormone transmembrane transporter activity L-amino acid transport phenylalanine transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane transmembrane transporter activity microvillus membrane positive regulation of interferon-gamma production positive regulation of interleukin-17 production positive regulation of interleukin-4 production xenobiotic transport intracellular membrane-bounded organelle transmembrane transport thyroid hormone transport amino acid import across plasma membrane external side of apical plasma membrane leucine import across plasma membrane L-leucine import across plasma membrane L-tryptophan transmembrane transport amino acid transport complex
TC0400000913.mm.2	Mtap	methylthioadenosine phosphorylase	4	89137369	NM_024433, BC003858 NM_024433, BC003858	66902	37	catalytic activity nucleus nucleoplasm cytoplasm cytosol cytosol purine ribonucleoside salvage nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring pentosyl groups S-methyl-5-thioadenosine phosphorylase activity L-methionine salvage from methylthioadenosine methylation	00270 01100
TC1100003221.mm.2	Rpa1	replication protein A1	11	-75300258	NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119	68275	73	telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome lateral element male germ cell nucleus in utero embryonic development nucleic acid binding DNA binding chromatin binding damaged DNA binding damaged DNA binding single-stranded DNA binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA unwinding involved in DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination cellular response to DNA damage stimulus telomere maintenance via telomerase positive regulation of cell population proliferation PML body hemopoiesis protein localization to chromosome single-stranded telomeric DNA binding metal ion binding homeostasis of number of cells within a tissue chromosome organization meiotic cell cycle meiotic cell cycle site of DNA damage G-rich strand telomeric DNA binding	03030 03420 03430 03440
TC0600001807.mm.2	Pon3	paraoxonase 3	6	-5216255	NM_173006, BC099416 NM_173006, BC099416	269823	29	aryldialkylphosphatase activity arylesterase activity arylesterase activity extracellular region extracellular space extracellular space response to toxic substance phenylacetate catabolic process hydrolase activity 3,4-dihydrocoumarin hydrolase activity aromatic compound catabolic process negative regulation of superoxide anion generation protein homodimerization activity intracellular membrane-bounded organelle coumarin catabolic process carboxylic acid catabolic process metal ion binding acyl-L-homoserine-lactone lactonohydrolase activity	01100
TC1500000710.mm.2	Adsl	adenylosuccinate lyase	15	80948489	NM_009634, BC020187 NM_009634, BC020187	11564	34	catalytic activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity mitochondrion cytosol cytosol purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process response to nutrient aerobic respiration purine ribonucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process lyase activity protein-containing complex identical protein binding 'de novo' AMP biosynthetic process (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	00230 00250 01100
TC0400003849.mm.2	Mrto4	mRNA turnover 4, ribosome maturation factor	4	-139347439	NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205	69902	26	ribosomal large subunit assembly nuclear-transcribed mRNA catabolic process intracellular anatomical structure nucleus nucleolus cytoplasm rRNA processing preribosome, large subunit precursor ribosome biogenesis ribosomal large subunit biogenesis
TC0X00001069.mm.2	Tlr13	toll-like receptor 13	X	106143274	NM_205820, BC117913, BC117914 NM_205820, BC117913, BC117914 NM_205820, BC117913, BC117914	279572	31	toll-like receptor signaling pathway immune system process MyD88-dependent toll-like receptor signaling pathway RNA binding protein binding cytoplasm endosome integral component of plasma membrane inflammatory response signal transduction response to virus membrane integral component of membrane hydrolase activity rRNA binding toll-like receptor 13 signaling pathway signaling receptor activity identical protein binding regulation of MAPK cascade innate immune response NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating
TC0700004321.mm.2	Sephs2	selenophosphate synthetase 2	7	-127271878	NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334	20768	20	nucleotide binding selenium compound metabolic process selenium compound metabolic process selenide, water dikinase activity selenide, water dikinase activity ATP binding cytoplasm selenocysteine biosynthetic process selenocysteine biosynthetic process kinase activity phosphorylation transferase activity metal ion binding	00450 01100
TC0700001951.mm.2	Dock1	dedicator of cytokinesis 1	7	134670686	NM_001033420	330662	46	hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleoplasm cytoplasm cytosol phagocytosis apoptotic process cytoskeleton organization small GTPase mediated signal transduction positive regulation of epithelial cell migration membrane cell migration nuclear speck SH3 domain binding guanyl-nucleotide exchange factor complex positive regulation of substrate adhesion-dependent cell spreading	04510 04810 05100
TC0700002999.mm.2	Cd37	CD37 antigen	7	-45233631, -45233631	NM_007645, BC019402, CD37 NM_007645, BC019402, CD37 NM_007645, BC019402, CD37	12493	34	immunological synapse positive regulation of immunoglobulin production regulation of humoral immune response integral component of plasma membrane negative regulation of cell population proliferation membrane integral component of membrane negative regulation of myeloid dendritic cell activation defense response to protozoan regulation of defense response to virus	04640
TC0200002478.mm.2	Mybl2	myeloblastosis oncogene-like 2	2	163054634	NM_008652, BC050842 NM_008652, BC050842	17865	77	mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated Myb complex positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mitotic spindle assembly cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding
TC1900000718.mm.2	Pdcd11	programmed cell death 11	19	47090765	NM_011053, BC070468 NM_011053, BC070468	18572	30	nucleic acid binding RNA binding nucleus nucleolus cytosol rRNA processing RNA processing mRNA processing transcription factor binding small-subunit processome
TC0600002045.mm.2					NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310			retinoid metabolic process retinal dehydrogenase activity tissue homeostasis epithelial cell maturation renal water homeostasis alditol:NADP+ 1-oxidoreductase activity alditol:NADP+ 1-oxidoreductase activity alditol:NADP+ 1-oxidoreductase activity extracellular space nucleoplasm cytoplasm cytosol cytosol monosaccharide metabolic process sorbitol biosynthetic process response to water deprivation response to organic substance oxidoreductase activity naphthalene metabolic process stress-activated protein kinase signaling cascade plasma membrane bounded cell projection cytoplasm paranodal junction regulation of urine volume regulation of urine volume norepinephrine metabolic process mast cell granule negative regulation of apoptotic process Schmidt-Lanterman incisure glyceraldehyde oxidoreductase activity daunorubicin metabolic process doxorubicin metabolic process positive regulation of receptor signaling pathway via JAK-STAT allyl-alcohol dehydrogenase activity perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation NADP-retinol dehydrogenase activity cellular response to hydrogen peroxide cellular hyperosmotic salinity response inner medullary collecting duct development metanephric collecting duct development cellular response to methylglyoxal Schwann cell microvillus
TC1100000822.mm.2	Pmp22	peripheral myelin protein 22	11	63131456, 63128981, 63132568, 63132802	NM_008885, BC010765 NM_008885, BC010765	18858	199	motor activity protein binding plasma membrane plasma membrane bicellular tight junction autophagy immune response cell cycle cell cycle arrest cell adhesion peripheral nervous system development mating adult walking behavior cholesterol metabolic process cell death negative regulation of cell population proliferation integrin complex adult locomotory behavior response to bacterium cell surface multicellular organism aging regulation of gene expression proteasomal protein catabolic process regulation of Schwann cell proliferation positive regulation of gene expression negative regulation of gene expression fibroblast migration negative regulation of neuron projection development Schwann cell differentiation Schwann cell development membrane integral component of membrane transmission of nerve impulse transmission of nerve impulse neuronal action potential propagation neuronal action potential myelination in peripheral nervous system myelination in peripheral nervous system lamellipodium assembly actin cytoskeleton organization cell differentiation paranodal junction assembly membrane raft organization bleb assembly myelin assembly myelin assembly regulation of glial cell apoptotic process cellular response to heat cellular response to unfolded protein response to endoplasmic reticulum stress multicellular organism growth Schwann cell migration gliogenesis myelination myelination proteasome-mediated ubiquitin-dependent protein catabolic process compact myelin compact myelin laminin complex cellular lipid metabolic process neuronal ion channel clustering perinuclear region of cytoplasm muscle fiber development peripheral nervous system neuron axonogenesis regulation of inflammatory response neuromuscular process striated muscle cell differentiation cellular localization vestibular reflex axon development motor behavior aggresome assembly basement membrane organization regulation of protein serine/threonine kinase activity neuromuscular junction development, skeletal muscle fiber regulation of apoptotic signaling pathway
TC0500001399.mm.2	P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	5	122643926, 122643926, 122650382, 122643926	NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120	18439	515	activation of MAPK activity cell morphogenesis lipopolysaccharide binding purinergic nucleotide receptor activity positive regulation of cytokine production phagolysosome assembly positive regulation of T cell mediated cytotoxicity positive regulation of protein phosphorylation extracellularly ATP-gated cation channel activity extracellularly ATP-gated cation channel activity extracellularly ATP-gated cation channel activity ion channel activity protein binding ATP binding integral component of nuclear inner membrane plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cell-cell junction protein phosphorylation membrane protein ectodomain proteolysis phospholipid transfer to membrane ion transport cation transport calcium ion transport cell volume homeostasis vesicle budding from membrane inflammatory response mitochondrion organization plasma membrane organization cell death cell death response to mechanical stimulus response to bacterium external side of plasma membrane response to organic substance response to zinc ion gene expression positive regulation of calcium ion transport into cytosol positive regulation of gene expression programmed cell death programmed cell death positive regulation of glutamate secretion positive regulation of gamma-aminobutyric acid secretion response to organic cyclic compound channel activity channel activity membrane membrane integral component of membrane synaptic vesicle exocytosis protein processing plasma membrane phospholipid scrambling sensory perception of pain protein catabolic process positive regulation of bone mineralization neuromuscular junction cellular response to extracellular stimulus bleb assembly bleb assembly positive regulation of prostaglandin secretion response to lipopolysaccharide response to lipopolysaccharide positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production collagen metabolic process response to ATP response to ATP response to ATP response to fluid shear stress positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway signaling receptor activity T cell proliferation response to drug identical protein binding neuronal cell body T cell homeostasis positive regulation of apoptotic process positive regulation of catalytic activity NAD transport negative regulation of MAPK cascade positive regulation of MAPK cascade synapse phospholipid translocation positive regulation of ossification negative regulation of bone resorption negative regulation of cell volume negative regulation of cell volume positive regulation of glycolytic process ceramide biosynthetic process pore complex assembly pore complex assembly skeletal system morphogenesis homeostasis of number of cells within a tissue positive regulation of protein secretion defense response to Gram-positive bacterium release of sequestered calcium ion into cytosol response to calcium ion response to calcium ion response to electrical stimulus membrane depolarization positive regulation of mitochondrial depolarization positive regulation of lymphocyte apoptotic process cellular response to dsRNA cellular response to organic cyclic compound reactive oxygen species metabolic process extrinsic apoptotic signaling pathway positive regulation of bleb assembly	04020 04080
TC1000001716.mm.2	Sash1	SAM and SH3 domain containing 1	10	-8722218	NM_175155, BC152995 NM_175155, BC152995	70097	22	protein polyubiquitination G-protein alpha-subunit binding cytoplasm protein C-terminus binding positive regulation of endothelial cell migration regulation of epithelial cell migration membrane protein kinase binding mitogen-activated protein kinase kinase kinase binding mitogen-activated protein kinase kinase kinase binding positive regulation of lipopolysaccharide-mediated signaling pathway protein-containing complex positive regulation of JUN kinase activity positive regulation of JUN kinase activity positive regulation of angiogenesis molecular adaptor activity regulation of protein K63-linked ubiquitination positive regulation of p38MAPK cascade positive regulation of NIK/NF-kappaB signaling positive regulation of NIK/NF-kappaB signaling regulation of protein autoubiquitination
TC1100003118.mm.2	C1qbp	complement component 1, q subcomponent binding protein	11	-70977845	NM_007573, BC038075 NM_007573, BC038075	12261	67	negative regulation of transcription by RNA polymerase II complement component C1q complex binding complement component C1q complex binding adaptive immune response immune system process transcription corepressor activity transcription corepressor activity mRNA binding mRNA binding protein kinase C binding protein binding hyaluronic acid binding hyaluronic acid binding extracellular region extracellular space nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol plasma membrane plasma membrane mRNA processing apoptotic process complement activation, classical pathway transcription factor binding transcription factor binding RNA splicing translation activator activity cell surface cell surface phosphatidylinositol 3-kinase signaling membrane regulation of complement activation regulation of complement activation kininogen binding kininogen binding adrenergic receptor binding negative regulation of interferon-gamma production negative regulation of interleukin-12 production negative regulation of MDA-5 signaling pathway negative regulation of RIG-I signaling pathway ribosome biogenesis mature ribosome assembly mature ribosome assembly mature ribosome assembly positive regulation of apoptotic process innate immune response positive regulation of cell adhesion negative regulation of mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome presynaptic active zone negative regulation of defense response to virus positive regulation of protein kinase B signaling positive regulation of mitochondrial translation positive regulation of mitochondrial translation positive regulation of neutrophil chemotaxis mitochondrial ribosome binding mitochondrial ribosome binding presynapse glutamatergic synapse GABA-ergic synapse positive regulation of substrate adhesion-dependent cell spreading positive regulation of trophoblast cell migration positive regulation of dendritic cell chemotaxis
TC0400002479.mm.2	Sigmar1	sigma non-opioid intracellular receptor 1	4	-41738492	NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930	18391	145	opioid receptor activity protein binding nucleus nuclear envelope endoplasmic reticulum endoplasmic reticulum lipid droplet plasma membrane lipid transport nervous system development postsynaptic density postsynaptic density membrane integral component of membrane cell junction cytoplasmic vesicle cell death in response to hydrogen peroxide signaling receptor activity identical protein binding cell projection regulation of neuron apoptotic process synapse postsynaptic membrane protein homotrimerization
TC1100001047.mm.2	Cluh	clustered mitochondria (cluA/CLU1) homolog	11	74649503	NM_001081158, BC072573 NM_001081158, BC072573	74148	19	mRNA binding mRNA binding cytoplasm cytoplasm mitochondrion organization intracellular distribution of mitochondria intracellular distribution of mitochondria
TC0700001689.mm.2	Xylt1	xylosyltransferase 1	7	117380978	NM_175645, BC157033 NM_175645, BC157033	233781	18	Golgi cis cisterna Golgi membrane extracellular space Golgi apparatus glycosaminoglycan biosynthetic process acetylglucosaminyltransferase activity heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein xylosyltransferase activity protein xylosyltransferase activity protein xylosyltransferase activity proteoglycan biosynthetic process chondroitin sulfate biosynthetic process cellular response to heat ossification involved in bone maturation metal ion binding negative regulation of axon regeneration embryonic skeletal system development chondroitin sulfate proteoglycan biosynthetic process chondroitin sulfate proteoglycan biosynthetic process	00532 00534 01100
TC0600002858.mm.2	Shq1	SHQ1 homolog (S. cerevisiae)	6	-100571810	NM_181590, BC052657 NM_181590, BC052657	72171	18	box H/ACA snoRNP assembly nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol ribonucleoprotein complex assembly positive regulation of apoptotic process unfolded protein binding negative regulation of rRNA processing
TC1100004233.mm.2	Fasn	fatty acid synthase	11	-120805957	NM_007988, BC046513 NM_007988, BC046513	14104	153	glandular epithelial cell development catalytic activity fatty acid synthase activity fatty acid synthase activity fatty acid synthase activity [acyl-carrier-protein] S-acetyltransferase activity [acyl-carrier-protein] S-malonyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity oleoyl-[acyl-carrier-protein] hydrolase activity cytoplasm mitochondrion Golgi apparatus cytosol plasma membrane acetyl-CoA metabolic process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process fatty acid biosynthetic process metabolic process ether lipid biosynthetic process biosynthetic process tissue development myristoyl-[acyl-carrier-protein] hydrolase activity palmitoyl-[acyl-carrier-protein] hydrolase activity acyl-[acyl-carrier-protein] hydrolase activity oxidoreductase activity transferase activity hydrolase activity hydrolase activity, acting on ester bonds lyase activity 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity neutrophil differentiation monocyte differentiation mammary gland development phosphopantetheine binding glycogen granule identical protein binding enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity cellular response to interleukin-4 establishment of endothelial intestinal barrier 3-oxo-glutaryl-[acp] methyl ester reductase activity 3-oxo-pimeloyl-[acp] methyl ester reductase activity	00061 01100 04910
TC1100001010.mm.2	Atp2a3	ATPase, Ca++ transporting, ubiquitous	11	72961168	NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147	53313	37	nucleotide binding calcium transmembrane transporter activity, phosphorylative mechanism calcium transmembrane transporter activity, phosphorylative mechanism calcium ion binding protein binding ATP binding endoplasmic reticulum endoplasmic reticulum ion transport calcium ion transport cellular calcium ion homeostasis cellular calcium ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process proton-exporting ATPase activity, phosphorylative mechanism cysteine-type endopeptidase activator activity involved in apoptotic process calcium ion transmembrane transporter activity membrane integral component of membrane sarcoplasmic reticulum ATPase activity calcium-dependent ATPase activity organelle membrane endoplasmic reticulum calcium ion homeostasis sarcoplasmic reticulum membrane ion channel binding metal ion binding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress calcium ion transmembrane transport calcium ion transmembrane transport negative regulation of receptor binding calcium ion transport from cytosol to endoplasmic reticulum	04020 04972 05010
TC0500000785.mm.2	Stap1	signal transducing adaptor family member 1	5	86071745	NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830	56792	26	phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity macrophage colony-stimulating factor receptor binding protein binding nucleus nucleoplasm cytoplasm mitochondrion transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to bacterium positive regulation of gene expression negative regulation of macrophage chemotaxis protein kinase binding protein kinase binding myeloid cell differentiation protein-macromolecule adaptor activity receptor tyrosine kinase binding protein-containing complex signaling adaptor activity signaling adaptor activity negative regulation of phosphorylation intracellular membrane-bounded organelle positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation positive regulation of non-membrane spanning protein tyrosine kinase activity negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity positive regulation of actin cytoskeleton reorganization
TC0X00001276.mm.2	Cenpi	centromere protein I	X	134308083	NM_145924, BC030328 NM_145924, BC030328	102920	14	chromosome, centromeric region kinetochore kinetochore molecular_function nucleus chromosome cytosol cytosol biological_process nuclear body nuclear body centromere complex assembly
TC0800001231.mm.2					NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773			nuclear outer membrane nucleoplasm cytosol protein import into nucleus protein import into nucleus protein import into nucleus protein export from nucleus nucleocytoplasmic transport structural constituent of nuclear pore small GTPase binding nuclear membrane positive regulation of protein import into nucleus identical protein binding nuclear pore central transport channel nuclear pore central transport channel nuclear import signal receptor activity protein localization to nuclear pore nucleocytoplasmic carrier activity negative regulation of vascular endothelial growth factor production
TC1500002221.mm.2	Cers5	ceramide synthase 5	15	-99735591	NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797	71949	46	DNA binding endoplasmic reticulum endoplasmic reticulum lipid metabolic process sphingolipid metabolic process membrane integral component of membrane N-acyltransferase activity transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity
TC0700000225.mm.2	Zc3h4	zinc finger CCCH-type containing 4	7	16401195	NM_198631, BC057627 NM_198631, BC057627	330474	35	nucleus nucleoplasm cytosol metal ion binding
TC0200001047.mm.2	Pdk1	pyruvate dehydrogenase kinase, isoenzyme 1	2	71873223, 71874903	NM_172665, BC027196 NM_172665, BC027196	228026	52	nucleotide binding protein kinase activity protein serine/threonine kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrion plasma membrane mitochondrial pyruvate dehydrogenase complex carbohydrate metabolic process glucose metabolic process protein phosphorylation protein phosphorylation cell surface receptor signaling pathway cell population proliferation intrinsic apoptotic signaling pathway in response to oxidative stress regulation of acetyl-CoA biosynthetic process from pyruvate regulation of glucose metabolic process regulation of glucose metabolic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation intracellular signal transduction identical protein binding protein-containing complex binding pyruvate dehydrogenase complex hypoxia-inducible factor-1alpha signaling pathway	04660 04664 04722 05145 05160
TC1500000420.mm.2	Trmt12	tRNA methyltransferase 12	15	58872648	NM_026642, BC052533, BC055850 NM_026642, BC052533, BC055850 NM_026642, BC052533, BC055850	68260	12	cytoplasm tRNA processing tRNA methyltransferase activity transferase activity tRNA methylation tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity
TC1800001632.mm.2	Haus1	HAUS augmin-like complex, subunit 1	18	-77757293, -77757293, -77757293	NM_146089, BC024400 NM_146089, BC024400	225745	17	molecular_function cytoplasm centrosome cytosol cytosol cytoskeleton microtubule cell cycle centrosome cycle centrosome cycle spindle assembly spindle assembly cell division HAUS complex HAUS complex mitotic spindle microtubule
TC1600001390.mm.2	Rfc4	replication factor C (activator 1) 4	16	-23113947	NM_145480, BC003335 NM_145480, BC003335	106344	29	nucleotide binding DNA binding DNA clamp loader activity DNA clamp loader activity ATP binding nucleus nucleoplasm DNA replication factor C complex DNA replication factor C complex DNA replication DNA-dependent DNA replication DNA repair single-stranded DNA helicase activity enzyme binding Ctf18 RFC-like complex Elg1 RFC-like complex positive regulation of DNA-directed DNA polymerase activity	03030 03420 03430
TC1700001084.mm.2	Ddx11	DEAD/H box helicase 11	17	66123519	NM_001003919, BC079656 NM_001003919, BC079656	320209	19	nucleotide binding chromatin spindle pole fibrillar center nucleic acid binding DNA binding DNA helicase activity DNA helicase activity chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding RNA binding single-stranded RNA binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytoskeleton nucleobase-containing compound metabolic process DNA replication DNA repair cellular response to DNA damage stimulus sister chromatid cohesion multicellular organism development DNA-dependent ATPase activity RNA-dependent ATPase activity hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides midbody replication fork processing Ctf18 RFC-like complex positive regulation of endodeoxyribonuclease activity negative regulation of protein binding DNA duplex unwinding DNA duplex unwinding establishment of sister chromatid cohesion positive regulation of chromatin binding G-quadruplex DNA unwinding triplex DNA binding positive regulation of sister chromatid cohesion metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding G-quadruplex DNA binding cellular response to hydroxyurea cellular response to cisplatin positive regulation of transcription of nucleolar large rRNA by RNA polymerase I cellular response to bleomycin nucleolar chromatin organization positive regulation of double-strand break repair
TC1900000099.mm.2	Cdca5	cell division cycle associated 5	19	6085096	NM_026410, BC052904 NM_026410, BC052904	67849	34	mitotic cell cycle mitotic cell cycle chromatin protein binding nucleus nucleus nucleoplasm chromosome cytoplasm double-strand break repair double-strand break repair cell cycle mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic chromosome condensation mitotic metaphase plate congression mitotic metaphase plate congression positive regulation of exit from mitosis positive regulation of exit from mitosis protein-containing complex binding cell division regulation of cohesin loading regulation of cohesin loading
TC0300002549.mm.2	Phgdh	3-phosphoglycerate dehydrogenase	3	-98313170	NM_016966, BC086668, BC110673 NM_016966, BC086668, BC110673 NM_016966, BC086668, BC110673	236539	59	phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity glutamine metabolic process glycine metabolic process L-serine metabolic process L-serine biosynthetic process threonine metabolic process cellular amino acid biosynthetic process gamma-aminobutyric acid metabolic process regulation of gene expression oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor taurine metabolic process spinal cord development glial cell development neural tube development neurogenesis neuron projection development myelin sheath NAD binding G1 to G0 transition	00260 01100
TC0700000861.mm.2	Dbp	D site albumin promoter binding protein	7	45705246	NM_016974, BC018323 NM_016974, BC018323	13170	76	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II circadian rhythm positive regulation of transcription by RNA polymerase II rhythmic process sequence-specific double-stranded DNA binding
TC1900001131.mm.2	Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	19	-11321038, -11321038	NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402	109225	12	molecular_function trans-Golgi network biological_process
TC0200004366.mm.2	Arhgap11a	Rho GTPase activating protein 11A	2	-113831491	NM_181416, BC050875 NM_181416, BC050875	228482	18	GTPase activator activity signal transduction
TC1500001750.mm.2	Eef1d	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	15	-75894795, -75894795	NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855	66656	35	fibrillar center DNA binding translation elongation factor activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytoplasm endoplasmic reticulum cytosol cytosol eukaryotic translation elongation factor 1 complex translation translational elongation mRNA transcription regulation of cell death heat shock protein binding activating transcription factor binding synapse synapse cellular response to ionizing radiation glutamatergic synapse glutamatergic synapse
TC0600001813.mm.2	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	6	-6041217	NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571	50799	49	L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity calcium ion binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane ATP biosynthetic process transport L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity aspartate transmembrane transport aspartate transmembrane transport aspartate transmembrane transport L-glutamate transmembrane transport L-glutamate transmembrane transport membrane integral component of membrane transmembrane transporter activity identical protein binding malate-aspartate shuttle malate-aspartate shuttle malate-aspartate shuttle cellular respiration metal ion binding response to calcium ion transmembrane transport
TC0400001770.mm.2	Padi2	peptidyl arginine deiminase, type II	4	140906359	NM_008812, BC040350, BC049947 NM_008812, BC040350, BC049947 NM_008812, BC040350, BC049947	18600	50	protein-arginine deiminase activity protein-arginine deiminase activity calcium ion binding nucleus cytoplasm cytoplasm regulation of chromatin disassembly hydrolase activity protein citrullination estrogen receptor binding intracellular estrogen receptor signaling pathway transcriptionally active chromatin histone H3-R26 citrullination histone citrullination protein homodimerization activity metal ion binding chromatin-mediated maintenance of transcription negative regulation of chemokine-mediated signaling pathway negative regulation of lymphocyte chemotaxis cellular response to leukemia inhibitory factor
TC1000002655.mm.2	Gas2l3	growth arrest-specific 2 like 3	10	-89408822	NM_001033331, NM_001079876, NM_001284344 NM_001033331, NM_001079876, NM_001284344 NM_001033331, NM_001079876, NM_001284344	237436	22	microtubule cytoskeleton organization microtubule cytoskeleton organization actin binding cytoplasm cytoskeleton microtubule actin filament microtubule binding microtubule binding cytoskeletal anchor activity response to bacterium actin cytoskeleton microtubule cytoskeleton actin cytoskeleton organization actin filament binding actin crosslink formation
TC0800002869.mm.2					NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654			molecular_function mitochondrion mitochondrion Golgi apparatus intra-Golgi vesicle-mediated transport positive regulation of cell population proliferation protein transport membrane Golgi transport complex Golgi transport complex peptidyl-methionine modification peptidyl-methionine modification N-terminal protein amino acid modification N-terminal protein amino acid modification peptide deformylase activity peptide deformylase activity co-translational protein modification
TC0700000057.mm.2	U2af2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2	7	5062142	NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF)	22185	42	commitment complex mRNA splicing, via spliceosome Prp19 complex nucleic acid binding RNA binding protein binding nucleus spliceosomal complex mRNA processing poly-pyrimidine tract binding RNA splicing nuclear speck nuclear speck nuclear speck enzyme binding pre-mRNA 3'-splice site binding pre-mRNA 3'-splice site binding negative regulation of protein ubiquitination positive regulation of RNA splicing negative regulation of mRNA splicing, via spliceosome C2H2 zinc finger domain binding U2-type prespliceosome U2-type prespliceosome U2AF complex U2AF complex	03040
TC0700002635.mm.2	Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	7	-25461701	NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926	26365	145	blood vessel development virus receptor activity negative regulation of cytokine production positive regulation of immunoglobulin production negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target actin binding granulocyte colony-stimulating factor receptor binding protein binding calmodulin binding extracellular space plasma membrane plasma membrane cell-cell junction adherens junction negative regulation of protein kinase activity homophilic cell adhesion via plasma membrane adhesion molecules external side of plasma membrane basal plasma membrane cell surface cell surface regulation of endothelial cell migration bile acid transmembrane transporter activity membrane integral component of membrane viral process apical plasma membrane lateral plasma membrane calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules kinase binding protein kinase binding protein phosphatase binding cell junction negative regulation of granulocyte differentiation filamin binding cytoplasmic vesicle brush border membrane negative regulation of interleukin-1 production negative regulation of interleukin-2 production Toll-like receptor binding common myeloid progenitor cell proliferation granulocyte colony-stimulating factor signaling pathway regulation of epidermal growth factor receptor signaling pathway T cell receptor complex positive regulation of T cell proliferation negative regulation of T cell proliferation identical protein binding protein homodimerization activity cell projection negative regulation of vascular permeability positive regulation of MAP kinase activity negative regulation by host of viral process negative regulation by host of viral process positive regulation by host of viral process negative regulation by host of viral genome replication cell-cell junction organization regulation of endothelial cell differentiation negative regulation of osteoclast differentiation negative regulation of bone resorption negative regulation of JNK cascade positive regulation of JNK cascade viral entry into host cell virion binding protein dimerization activity Peyer's patch development negative regulation of lipid biosynthetic process ciliary membrane regulation of blood vessel remodeling positive regulation of activation-induced cell death of T cells positive regulation of calcineurin-NFAT signaling cascade negative regulation of platelet aggregation insulin catabolic process regulation of sprouting angiogenesis protein tyrosine kinase binding protein tyrosine kinase binding negative regulation of hepatocyte proliferation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD8-positive, alpha-beta T cell activation positive regulation of vasculogenesis
TC0700000904.mm.2	Prmt3	protein arginine N-methyltransferase 3	7	49778357	NM_133740, BC050775 NM_133740, BC050775	71974	35	protein binding cytoplasm cytosol protein methylation methyltransferase activity protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine negative regulation of protein ubiquitination methylation protein-arginine omega-N asymmetric methyltransferase activity ribosome binding metal ion binding dendritic spine morphogenesis modified amino acid binding
TC0300003106.mm.2	Prkacb	protein kinase, cAMP dependent, catalytic, beta	3	-146729578, -146729578, -146729578, -146729578	NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533	18749	67	nucleotide binding magnesium ion binding magnesium ion binding neural tube closure protein kinase activity protein serine/threonine kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity ATP binding ATP binding nucleus nucleus cytoplasm centrosome cytosol cytosol plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex protein phosphorylation protein phosphorylation G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway protein kinase A signaling membrane kinase activity phosphorylation transferase activity ubiquitin protein ligase binding protein kinase A regulatory subunit binding perinuclear region of cytoplasm negative regulation of meiotic cell cycle regulation of protein processing ciliary base negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	04010 04020 04062 04114 04210 04270 04310 04340 04540 04720 04740 04742 04910 04912 04914 04916 04962 04970 04971 04976 05020 05146 05414
TC0400001274.mm.2	Eif2b3	eukaryotic translation initiation factor 2B, subunit 3	4	117019401, 117019401	NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658	108067	22	cytoplasmic translational initiation translation initiation factor activity translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm eukaryotic translation initiation factor 2B complex eukaryotic translation initiation factor 2B complex translational initiation translation factor activity, RNA binding response to heat response to glucose oligodendrocyte development guanyl-nucleotide exchange factor complex response to peptide hormone T cell receptor signaling pathway	03013
TC0700003829.mm.2	P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	7	-100937633	NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095	233571	54	G protein-coupled ADP receptor activity G protein-coupled receptor activity plasma membrane phagocytosis signal transduction G protein-coupled receptor signaling pathway positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane pyrimidine nucleotide binding transepithelial chloride transport positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor activity G protein-coupled UDP receptor activity G protein-coupled UDP receptor activity G protein-coupled UTP receptor activity positive regulation of ERK1 and ERK2 cascade cellular response to prostaglandin E stimulus cellular response to organic cyclic compound cellular response to purine-containing compound positive regulation of vascular associated smooth muscle cell proliferation cellular response to pyrimidine ribonucleotide	04080
TC1300001190.mm.2	Dimt1	DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)	13	106947128	NM_025447, BC019799 NM_025447, BC019799	66254	18	rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding nucleus nucleoplasm nucleolus mitochondrial matrix cytosol rRNA processing methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation rRNA methylation methylation 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity positive regulation of rRNA processing
TC0300001289.mm.2	Zgrf1	zinc finger, GRF-type containing 1	3	127553488	NM_197997	71643	15	RNA binding cytoplasm zinc ion binding membrane integral component of membrane 5'-flap endonuclease activity metal ion binding replication fork reversal
TC0300002730.mm.2	Ampd2	adenosine monophosphate deaminase 2	3	-108074061, -108074058, -108074061	NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119	109674	31	AMP deaminase activity AMP deaminase activity AMP deaminase activity cytosol cytosol IMP biosynthetic process IMP biosynthetic process IMP biosynthetic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity IMP salvage cholesterol homeostasis identical protein binding AMP metabolic process AMP metabolic process ATP metabolic process ATP metabolic process GTP metabolic process GTP metabolic process metal ion binding cyclic purine nucleotide metabolic process glomerular visceral epithelial cell development energy homeostasis energy homeostasis	00230 01100
TC1400002600.mm.2	Dis3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease	14	-99076633	NM_028315, BC027357 NM_028315, BC027357	72662	27	3'-5'-exoribonuclease activity 3'-5'-exoribonuclease activity nuclear exosome (RNase complex) nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) RNA binding nuclease activity endonuclease activity endonuclease activity exonuclease activity ribonuclease activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytosol rRNA processing rRNA catabolic process rRNA catabolic process hydrolase activity CUT catabolic process	03018
TC0800001436.mm.2	6430548M08Rik	RIKEN cDNA 6430548M08 gene	8	120114151, 120114151, 120144928	NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126	234797	15	molecular_function cellular_component biological_process
TC1000000240.mm.2	Arhgap18	Rho GTPase activating protein 18	10	26772511	NM_176837, BC030858 NM_176837, BC030858	73910	22	ruffle GTPase activator activity GTPase activator activity cytoplasm cytoplasm cytosol cytoplasmic microtubule plasma membrane signal transduction small GTPase mediated signal transduction regulation of cell shape nuclear speck regulation of actin filament polymerization regulation of actin filament polymerization regulation of actin cytoskeleton organization regulation of small GTPase mediated signal transduction regulation of small GTPase mediated signal transduction regulation of cell motility
TC1100004054.mm.2	Cd300c2	CD300C molecule 2	11	-114996768	NM_134158, BC006801 NM_134158, BC006801	140497	21	positive regulation of cytokine production immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane plasma membrane membrane integral component of membrane
TC0700001348.mm.2	Alg8	asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)	7	97371616	NM_199035, BC061244 NM_199035, BC061244	381903	20	alpha-1,3-mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups protein N-linked glycosylation via asparagine dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	00510 01100
TC0100003814.mm.2	Dtl	denticleless E3 ubiquitin protein ligase	1	-191537355	NM_029766	76843	33	protein polyubiquitination ubiquitin-protein transferase activity nucleus nucleoplasm chromosome nucleolus cytoplasm centrosome cytosol cytoskeleton DNA replication ubiquitin-dependent protein catabolic process protein monoubiquitination cellular response to DNA damage stimulus response to UV positive regulation of G2/M transition of mitotic cell cycle membrane translesion synthesis Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex positive regulation of protein catabolic process rhythmic process regulation of cell cycle signal transduction involved in G2 DNA damage checkpoint Cul4-RING E3 ubiquitin ligase complex
TC1500001192.mm.2	Skp2	S-phase kinase-associated protein 2	15	-9111981, -9111981	NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468	27401	133	G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle protein polyubiquitination protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of intracellular estrogen receptor signaling pathway identical protein binding regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process innate immune response positive regulation of smooth muscle cell proliferation defense response to virus regulation of cell cycle regulation of cell cycle protein K48-linked ubiquitination positive regulation of protein polyubiquitination	04110 04120 05200 05222
TC1400002215.mm.2	Fdft1	farnesyl diphosphate farnesyl transferase 1	14	-63145150, -63145150	NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302	14137	44	catalytic activity farnesyl-diphosphate farnesyltransferase activity farnesyl-diphosphate farnesyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process ergosterol biosynthetic process metabolic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process lipid biosynthetic process biosynthetic process membrane integral component of membrane sterol biosynthetic process transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups intracellular membrane-bounded organelle farnesyl diphosphate metabolic process farnesyl diphosphate metabolic process metal ion binding squalene synthase activity	00100 01100
TC1400001785.mm.2	Prxl2a	peroxiredoxin like 2A	14	-40993734, -40993734, -40993734, -40993734, -40993734	NM_027464, BC056635 NM_027464, BC056635	70564	25	extracellular region cytoplasm cytoplasm mitochondrion antioxidant activity antioxidant activity regulation of osteoclast differentiation
TC0700001455.mm.2	Rrm1	ribonucleotide reductase M1	7	102441694	NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217	20133	53	nucleotide binding catalytic activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding ATP binding nuclear envelope cytoplasm cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity purine nucleotide binding identical protein binding cell projection neuronal cell body protein heterotetramerization ribonucleoside-diphosphate reductase activity disordered domain specific binding	00230 00240 00480 01100
TC0100000469.mm.2	Cyp20a1	cytochrome P450, family 20, subfamily a, polypeptide 1	1	60343299	NM_030013, BC049147 NM_030013, BC049147	77951	17	monooxygenase activity iron ion binding membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding metal ion binding
TC0900001851.mm.2	Dnmt1	DNA methyltransferase (cytosine-5) 1	9	-20907205, -20907205, -20907205	NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047	13433	442	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II heterochromatin DNA binding DNA binding chromatin binding RNA binding catalytic activity DNA (cytosine-5-)-methyltransferase activity DNA (cytosine-5-)-methyltransferase activity protein binding nucleus nucleus nucleus nucleoplasm replication fork pericentric heterochromatin cytoplasm DNA methylation DNA methylation chromatin organization Ras protein signal transduction metabolic process methyltransferase activity zinc ion binding methyl-CpG binding DNA-methyltransferase activity DNA-methyltransferase activity maintenance of DNA methylation maintenance of DNA methylation DNA methylation on cytosine within a CG sequence regulation of gene expression positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression gene silencing transferase activity protein domain specific binding estrogen receptor binding methylation DNA methylation on cytosine DNA methylation on cytosine protein-containing complex regulation of cell population proliferation response to drug histone deacetylase binding neuronal cell body DNA methylation involved in embryo development DNA hypermethylation negative regulation of transcription, DNA-templated S-adenosylmethionine metabolic process metal ion binding positive regulation of histone H3-K4 methylation negative regulation of histone H3-K9 methylation DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates cellular response to amino acid stimulus cellular response to transforming growth factor beta stimulus C-5 methylation of cytosine positive regulation of DNA methylation-dependent heterochromatin assembly positive regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching promoter-specific chromatin binding	00270 01100
TC1100000774.mm.2	Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	11	61142483, 61126754	NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868	57916	81	B cell homeostasis B cell homeostasis B cell homeostasis hematopoietic progenitor cell differentiation hematopoietic progenitor cell differentiation adaptive immune response immune system process integral component of plasma membrane external side of plasma membrane membrane integral component of membrane negative regulation of B cell proliferation negative regulation of B cell proliferation	04060 04672 05340
TC0100000297.mm.2	Il1rl2	interleukin 1 receptor-like 2	1	40324588	NM_133193, BC117797 NM_133193, BC117797	107527	33	immune system process cytokine receptor activity interleukin-1 receptor activity interleukin-1, type I, activating receptor activity cellular_component inflammatory response signal transduction membrane integral component of membrane hydrolase activity positive regulation of interleukin-6 production innate immune response positive regulation of T cell differentiation NAD(P)+ nucleosidase activity regulation of inflammatory response regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating
TC0700001736.mm.2	Eef2k	eukaryotic elongation factor-2 kinase	7	120843599, 120851188, 120842830	NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826	13631	47	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding calmodulin binding ATP binding translational elongation protein phosphorylation translation factor activity, RNA binding postsynaptic density kinase activity phosphorylation transferase activity regulation of protein autophosphorylation negative regulation of apoptotic process dendritic spine positive regulation of endocytosis protein autophosphorylation positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis
TC0500001270.mm.2	Cit	citron	5	115845655	NM_007708, BC023775, BC051165 NM_007708, BC023775, BC051165 NM_007708, BC023775, BC051165	12704	52	mitotic sister chromatid segregation G2/M transition of mitotic cell cycle nucleotide binding mitotic cell cycle mitotic cytokinesis cytokinesis transcription coactivator binding ruffle protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm vacuole cytosol cytosol cytoskeleton plasma membrane protein phosphorylation Golgi organization cell cycle metaphase/anaphase transition of mitotic cell cycle multicellular organism development spermatogenesis nervous system development regulation of actin polymerization or depolymerization actin cytoskeleton kinase activity phosphorylation dendrite development transferase activity SH3 domain binding peptidyl-threonine phosphorylation protein kinase binding cell differentiation PDZ domain binding protein serine/threonine kinase inhibitor activity midbody actomyosin structure organization Golgi cisterna cleavage furrow positive regulation of cytokinesis negative regulation of hippo signaling intracellular signal transduction neuronal cell body negative regulation of neuron differentiation metal ion binding generation of neurons negative regulation of dendrite morphogenesis cell division neuron apoptotic process scaffold protein binding
TC1100001051.mm.2	Tsr1	TSR1 20S rRNA accumulation	11	74898079	NM_177325, BC031531 NM_177325, BC031531	104662	25	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus preribosome, small subunit precursor U3 snoRNA binding ribosome biogenesis
TC0100001602.mm.2	Cd84	CD84 antigen	1	171839696, 171839696	NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84	12523	34	adaptive immune response immune system process plasma membrane autophagy cell adhesion membrane integral component of membrane regulation of lipopolysaccharide-mediated signaling pathway negative regulation of granulocyte macrophage colony-stimulating factor production negative regulation of interleukin-10 production negative regulation of interleukin-18 production negative regulation of interleukin-6 production positive regulation of tumor necrosis factor production negative regulation of mast cell activation identical protein binding regulation of macrophage activation intracellular membrane-bounded organelle negative regulation of mast cell degranulation positive regulation of MAPK cascade innate immune response positive regulation of NF-kappaB transcription factor activity positive regulation of monocyte chemotactic protein-1 production regulation of store-operated calcium entry
TC0200005334.mm.2					NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480			negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II
TC1000002686.mm.2	Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	10	-92684744	NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870	17997	34	pericentriolar material pericentriolar material spindle pole spindle pole gamma-tubulin ring complex, centrosomal nucleoplasm cytoplasm centrosome centrosome centriole centriole cytoskeleton plasma membrane microtubule depolymerization cell cycle microtubule polymerization or depolymerization ciliary basal body ciliary basal body apical part of cell cell division regulation of establishment of protein localization protein localization to centrosome
TC0200001675.mm.2	Aven	apoptosis, caspase activation inhibitor	2	112571612, 112492963, 112559681, 112559281, 112618416	NM_001165935, NM_028844, BC100725 NM_001165935, NM_028844, BC100725 NM_001165935, NM_028844, BC100725	74268	21	molecular_function apoptotic process negative regulation of G2/M transition of mitotic cell cycle membrane membrane negative regulation of apoptotic process negative regulation of apoptotic process
TC0100001114.mm.2	Mgat5	mannoside acetylglucosaminyltransferase 5	1	127204985	NM_145128, BC125533, BC125535 NM_145128, BC125533, BC125535 NM_145128, BC125533, BC125535	107895	63	protein phosphatase inhibitor activity extracellular region Golgi apparatus Golgi apparatus protein N-linked glycosylation protein N-linked glycosylation protein N-linked glycosylation protein N-linked glycosylation acetylglucosaminyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein N-linked glycosylation via asparagine alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity manganese ion binding positive regulation of cell migration negative regulation of protein tyrosine phosphatase activity positive regulation of receptor signaling pathway via STAT	00510 01100
TC1000002944.mm.2	Nup107	nucleoporin 107	10	-117750642	NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261	103468	26	chromosome, centromeric region kinetochore posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore chromosome regulation of transcription, DNA-templated mRNA export from nucleus mRNA export from nucleus protein import into nucleus female gonad development protein transport membrane structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring nuclear pore outer ring nuclear membrane nuclear periphery mRNA transport nuclear pore complex assembly nephron development	03013
TC0700004291.mm.2	Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	7	-126672864	NM_133670, BC005413 NM_133670, BC005413	20887	40	nucleotide binding aryl sulfotransferase activity aryl sulfotransferase activity cytoplasm cytosol catecholamine metabolic process lipid metabolic process xenobiotic metabolic process sulfotransferase activity sulfotransferase activity sulfotransferase activity steroid metabolic process estrogen metabolic process transferase activity tyrosine-ester sulfotransferase activity drug metabolic process 4-nitrophenol metabolic process identical protein binding 3'-phosphoadenosine 5'-phosphosulfate binding response to glucocorticoid sulfation sulfation sulfation	00920
TC1800000794.mm.2	Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	18	74779211	NM_177470, BC028901 NM_177470, BC028901	52538	34	catalytic activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA hydrolase activity acetyl-CoA C-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix acetyl-CoA metabolic process lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation palmitoyl-CoA hydrolase activity transferase activity transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups hydrolase activity acyl-CoA hydrolase activity cellular response to hypoxia myristoyl-CoA hydrolase activity negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway negative regulation of mitochondrial membrane permeability involved in apoptotic process	00062 00071 00280 01100
TC1400000578.mm.2					NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843			angiogenesis angiogenesis response to hypoxia response to yeast response to yeast positive regulation of endothelial cell proliferation nucleic acid binding DNA binding RNA binding actin binding nuclease activity endonuclease activity ribonuclease activity ribonuclease activity ribonuclease activity signaling receptor binding copper ion binding extracellular region extracellular region extracellular region basement membrane extracellular space extracellular space extracellular space nucleus chromosome nucleolus diacylglycerol biosynthetic process activation of phospholipase C activity multicellular organism development central nervous system development heparin binding cellular response to starvation rRNA transcription response to hormone actin cytoskeleton cell migration hydrolase activity negative regulation of translation antibacterial humoral response antibacterial humoral response antibacterial humoral response antifungal humoral response antifungal humoral response cell differentiation growth cone cytoplasmic vesicle activation of protein kinase B activity angiogenin-PRI complex activation of phospholipase A2 activity peptide binding positive regulation of phosphorylation protein homodimerization activity neuronal cell body innate immune response innate immune response innate immune response negative regulation of smooth muscle cell proliferation positive regulation of protein secretion defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide RNA phosphodiester bond hydrolysis
TC0700000647.mm.2	Pepd	peptidase D	7	34912406	NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973	18624	40	aminopeptidase activity peptidase activity peptidase activity metallopeptidase activity hydrolase activity dipeptidase activity manganese ion binding collagen catabolic process metal ion binding proline dipeptidase activity
TC0600003474.mm.2	Sinhcaf	SIN3-HDAC complex associated factor	6	-148921058, -148921058	NM_019643, BC076599 NM_019643, BC076599	56306	28	protein binding nucleus positive regulation of cell population proliferation Sin3 complex Sin3 complex negative regulation of cell migration negative regulation of cell migration negative regulation of cell differentiation
TC0100003483.mm.2	Mgst3	microsomal glutathione S-transferase 3	1	-167371965	NM_025569, BC029669 NM_025569, BC029669	66447	28	glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity glutathione peroxidase activity nuclear envelope endoplasmic reticulum lipid metabolic process membrane integral component of membrane oxidoreductase activity transferase activity leukotriene biosynthetic process identical protein binding intracellular membrane-bounded organelle	00480 00980 00982
TC1200001598.mm.2	Dus4l	dihydrouridine synthase 4-like (S. cerevisiae)	12	-31640054	NM_028002, BC109351 NM_028002, BC109351	71916	15	catalytic activity tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity flavin adenine dinucleotide binding
TC0400002271.mm.2	Wwp1	WW domain containing E3 ubiquitin protein ligase 1	4	-19608299	NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812	107568	40	protein polyubiquitination ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus cytoplasm cytosol plasma membrane ubiquitin-dependent protein catabolic process membrane protein ubiquitination protein ubiquitination protein ubiquitination transferase activity T cell differentiation lung development proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process negative regulation of transcription, DNA-templated ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity	04120 04144
TC1400001935.mm.2	Dlgap5	DLG associated protein 5	14	-47387778	NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949	218977	24	nucleus nucleus cytoplasm mitochondrion cytosol cytoskeleton cell cycle mitotic spindle organization chromosome segregation regulation of mitotic cell cycle microtubule binding signaling spindle pole centrosome spindle pole centrosome centriolar satellite kinetochore assembly centrosome localization
TC0200000651.mm.2	Ptgs1	prostaglandin-endoperoxide synthase 1	2	36230425	NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322	19224	299	prostaglandin biosynthetic process prostaglandin biosynthetic process photoreceptor outer segment peroxidase activity prostaglandin-endoperoxide synthase activity nuclear envelope cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process inflammatory response response to oxidative stress learning memory regulation of blood pressure negative regulation of norepinephrine secretion membrane oxidoreductase activity sensory perception of pain cyclooxygenase pathway heme binding keratinocyte differentiation negative regulation of epinephrine secretion maintenance of blood-brain barrier regulation of cell population proliferation intracellular membrane-bounded organelle positive regulation of vasoconstriction positive regulation of smooth muscle contraction metal ion binding dioxygenase activity	00590 01100
TC0800000114.mm.2	F7	coagulation factor VII	8	13026033	NM_010172, BC061149 NM_010172, BC061149	14068	48	positive regulation of leukocyte chemotaxis positive regulation of leukocyte chemotaxis endopeptidase activity serine-type endopeptidase activity signaling receptor binding calcium ion binding extracellular region extracellular region extracellular space extracellular space proteolysis blood coagulation blood coagulation blood coagulation hemostasis peptidase activity serine-type peptidase activity positive regulation of platelet-derived growth factor receptor signaling pathway protein processing hydrolase activity positive regulation of blood coagulation response to nutrient levels vesicle positive regulation of positive chemotaxis positive regulation of protein kinase B signaling response to anticoagulant response to cholesterol response to astaxanthin serine-type peptidase complex	04610
TC0400000662.mm.2	Snx30	sorting nexin family member 30	4	59805649	NM_172468, BC099674 NM_172468, BC099674	209131	14	cytoplasm protein transport phosphatidylinositol binding
TC1000003220.mm.2	Nt5dc3	5'-nucleotidase domain containing 3	10	86779004	NM_175331, BC172705 NM_175331, BC172705	103466	20	mitochondrion cytosol 5'-nucleotidase activity hydrolase activity receptor complex metal ion binding
TC1300000330.mm.2	Mboat1	membrane bound O-acyltransferase domain containing 1	13	30136489	NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653	218121	18	endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phospholipid biosynthetic process regulation of neuron projection development membrane integral component of membrane transferase activity transferase activity, transferring acyl groups lipid modification phosphatidylserine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoserine O-acyltransferase activity	00561 00564 01100
TC0900001582.mm.2	Exog	endo/exonuclease (5'-3'), endonuclease G-like	9	119444959	NM_001172136, NM_172456, BC119024 NM_001172136, NM_172456, BC119024 NM_001172136, NM_172456, BC119024	208194	20	single-stranded DNA endodeoxyribonuclease activity nucleic acid binding nuclease activity endonuclease activity endonuclease activity endoribonuclease activity nucleus mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane apoptotic DNA fragmentation 5'-3' exonuclease activity 5'-3' exonuclease activity membrane hydrolase activity protein-containing complex metal ion binding	04210
TC1000000830.mm.2	Wdr18	WD repeat domain 18	10	79960151	NM_175450, BC095984 NM_175450, BC095984	216156	29	molecular_function nucleus nucleoplasm nuclear pre-replicative complex cytoplasm rRNA processing multicellular organism development regulation of DNA-dependent DNA replication initiation Rix1 complex
TC1800001437.mm.2	Adrb2	adrenergic receptor, beta 2	18	-62177712	NM_007420, BC032883 NM_007420, BC032883	11555	345	amyloid-beta binding G-protein alpha-subunit binding regulation of systemic arterial blood pressure by norepinephrine-epinephrine diet induced thermogenesis norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure regulation of sodium ion transport desensitization of G protein-coupled receptor signaling pathway by arrestin diaphragm contraction positive regulation of the force of heart contraction by epinephrine G protein-coupled receptor activity adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity protein binding nucleus nucleus cytoplasm endosome Golgi apparatus plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola receptor-mediated endocytosis regulation of smooth muscle contraction signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase binding positive regulation of cell population proliferation associative learning response to cold positive regulation of protein kinase A signaling positive regulation of protein kinase A signaling positive regulation of sodium ion transport potassium channel regulator activity membrane membrane integral component of membrane apical plasma membrane negative regulation of angiogenesis enzyme binding negative regulation of ossification axon dendrite positive regulation of bone mineralization heat generation B2 bradykinin receptor binding positive regulation of ATPase activity neuronal cell body membrane synaptic transmission, glutamatergic ionotropic glutamate receptor binding negative regulation of urine volume negative regulation of multicellular organism growth wound healing sarcolemma identical protein binding protein homodimerization activity positive regulation of apoptotic process dendritic spine intracellular membrane-bounded organelle receptor complex positive regulation of potassium ion transport positive regulation of MAPK cascade protein-containing complex binding bone resorption positive regulation of heart contraction positive regulation of transcription by RNA polymerase II negative regulation of smooth muscle contraction negative regulation of smooth muscle contraction positive regulation of skeletal muscle tissue growth negative regulation of inflammatory response brown fat cell differentiation norepinephrine binding norepinephrine binding protein phosphatase 2A binding regulation of calcium ion transport regulation of sensory perception of pain excitatory postsynaptic potential positive regulation of mini excitatory postsynaptic potential cellular response to hypoxia adrenergic receptor signaling pathway adenylate cyclase-activating adrenergic receptor signaling pathway positive regulation of protein serine/threonine kinase activity negative regulation of platelet aggregation receptor-receptor interaction blood vessel diameter maintenance glutamatergic synapse positive regulation of cold-induced thermogenesis positive regulation of autophagosome maturation positive regulation of lipophagy cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of calcium ion import across plasma membrane regulation of synaptic vesicle exocytosis positive regulation of AMPA receptor activity	04020 04080 04144 04970
TC1900001336.mm.2	Ak3	adenylate kinase 3	19	-29020831	NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191	56248	23	nucleotide binding adenylate kinase activity adenylate kinase activity ATP binding GTP binding cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial intermembrane space mitochondrial matrix mitochondrial matrix mitochondrial matrix nucleobase-containing compound metabolic process ADP biosynthetic process AMP phosphorylation nucleoside triphosphate biosynthetic process kinase activity phosphorylation transferase activity phosphotransferase activity, phosphate group as acceptor nucleobase-containing compound kinase activity identical protein binding AMP metabolic process AMP metabolic process ATP metabolic process GTP metabolic process ITP metabolic process UTP metabolic process dATP metabolic process nucleoside triphosphate adenylate kinase activity nucleoside triphosphate adenylate kinase activity	00240
TC1500000742.mm.2	Srebf2	sterol regulatory element binding factor 2	15	82147268	NM_033218, BC167259 NM_033218, BC167259	20788	149	negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II lipid metabolic process protein C-terminus binding steroid metabolic process cholesterol metabolic process cellular response to starvation response to hormone positive regulation of cholesterol storage positive regulation of cholesterol storage membrane integral component of membrane dendrite cytoplasmic vesicle SREBP signaling pathway SREBP-SCAP-Insig complex cholesterol homeostasis intracellular membrane-bounded organelle sequence-specific DNA binding positive regulation of cholesterol biosynthetic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein dimerization activity E-box binding negative regulation of cholesterol efflux positive regulation of pri-miRNA transcription by RNA polymerase II sequence-specific double-stranded DNA binding
TC1900001514.mm.2	Exosc1	exosome component 1	19	-41922979	NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423	66583	25	nuclear exosome (RNase complex) exosome (RNase complex) RNA binding protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing	03018
TC0100003449.mm.2	Mpzl1	myelin protein zero-like 1	1	-165592175, -165592180	NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563	68481	23	protein binding integral component of plasma membrane signal transduction membrane integral component of membrane positive regulation of cell migration	04514
TC0100002838.mm.2	Dtymk	deoxythymidylate kinase	1	-93792575, -93800494	NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902	21915	24	nucleotide binding nucleoside diphosphate kinase activity thymidylate kinase activity thymidylate kinase activity thymidylate kinase activity ATP binding nucleus cytoplasm mitochondrion mitochondrion mitochondrial intermembrane space mitochondrial matrix cytosol dUDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process dTTP biosynthetic process uridylate kinase activity nucleotide biosynthetic process kinase activity phosphorylation transferase activity cellular response to growth factor stimulus	00240 01100
TC0800000328.mm.2	Plpp5	phospholipid phosphatase 5	8	25720047	NM_028000	71910	16	diacylglycerol diphosphate phosphatase activity plasma membrane lipid metabolic process phosphatidate phosphatase activity phosphatidate phosphatase activity membrane integral component of membrane hydrolase activity phospholipid dephosphorylation phospholipid dephosphorylation
TC0300001046.mm.2	Dennd2c	DENN/MADD domain containing 2C	3	103140325, 103127555, 103102658	NM_177857, BC060666 NM_177857, BC060666	329727	21	guanyl-nucleotide exchange factor activity nucleoplasm
TC1500001181.mm.2
TC0200004598.mm.2	Ckap2l	cytoskeleton associated protein 2-like	2	-129268209	NM_181589, BC053443 NM_181589, BC053443	70466	18	molecular_function cytoplasm centrosome centrosome cytosol cytosol cytoskeleton biological_process mitotic spindle mitotic spindle
TC0800001863.mm.2	Ckap2	cytoskeleton associated protein 2	8	-22168151	NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023	80986	26	mitotic cytokinesis molecular_function cytoplasm centrosome cytosol cytoskeleton microtubule apoptotic process negative regulation of microtubule depolymerization cell cycle microtubule cytoskeleton microtubule cytoskeleton positive regulation of transcription by RNA polymerase II
TC0600001401.mm.2	Clec4a2	C-type lectin domain family 4, member a2	6	123122689, 123123315	NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565	26888	24	negative regulation of cytokine production adaptive immune response immune system process plasmacytoid dendritic cell antigen processing and presentation calcium ion binding mannose binding plasma membrane membrane integral component of membrane carbohydrate binding carbohydrate binding negative regulation of tumor necrosis factor production CD8-positive, alpha-beta T cell activation antigen processing and presentation of exogenous peptide antigen via MHC class I innate immune response metal ion binding
TC0200005476.mm.2	Nup35	nucleoporin 35	2	80639263, 80638811	NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814	69482	22	nucleic acid binding single-stranded DNA binding phospholipid binding nucleus nuclear pore nuclear lamina nucleoplasm plasma membrane regulation of transcription, DNA-templated NLS-bearing protein import into nucleus nuclear pore organization protein transport membrane structural constituent of nuclear pore nuclear membrane identical protein binding nuclear pore central transport channel nuclear pore nuclear basket mRNA transport cellular response to leukemia inhibitory factor	03013
TC1000002175.mm.2	Man1a	mannosidase 1, alpha	10	-53904784	NM_008548, BC015265 NM_008548, BC015265	17155	30	Golgi membrane Golgi membrane catalytic activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus cytosol N-glycan processing metabolic process membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds ubiquitin-dependent ERAD pathway cytoplasmic vesicle protein targeting to ER metal ion binding mannose trimming involved in glycoprotein ERAD pathway	00510 01100 04141
TC1200002242.mm.2	Fbln5	fibulin 5	12	-101746564, -101746564	NM_011812, BC006636 NM_011812, BC006636	23876	75	negative regulation of transcription by RNA polymerase II integrin binding calcium ion binding protein binding extracellular region extracellular region extracellular space extracellular space cell adhesion protein C-terminus binding negative regulation of angiogenesis extracellular matrix constituent conferring elasticity extracellular matrix organization positive regulation of osteoblast proliferation protein localization to cell surface protein homodimerization activity positive regulation of transcription by RNA polymerase II secretion elastic fiber assembly elastic fiber assembly elastic fiber assembly collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix elastic fiber intramembranous bone growth regulation of removal of superoxide radicals
TC1300000838.mm.2	Fastkd3	FAST kinase domains 3	13	68582209	NM_027123, BC042506, BC060688 NM_027123, BC042506, BC060688 NM_027123, BC042506, BC060688	69577	14	protein kinase activity nucleoplasm mitochondrion mitochondrion mitochondrial cytochrome c oxidase assembly regulation of mitochondrial mRNA stability positive regulation of mitochondrial translation
TC1300002204.mm.2	Ctsl	cathepsin L	13	-64361889	NM_009984, BC068163 NM_009984, BC068163	13039	210	endopeptidase activity aminopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region extracellular space extracellular space nucleus nucleolus cytoplasm lysosome lysosome lysosome vacuole plasma membrane microvillus proteolysis proteolysis thyroid hormone generation immune response cell communication peptidase activity cysteine-type peptidase activity external side of plasma membrane external side of plasma membrane negative regulation of keratinocyte proliferation membrane protein processing protein processing protein autoprocessing hydrolase activity cysteine-type carboxypeptidase activity secretory granule collagen catabolic process kininogen binding hair follicle morphogenesis cytoplasmic vesicle peptide binding histone binding catagen neuron projection perikaryon CD4-positive, alpha-beta T cell lineage commitment protein-containing complex binding apical part of cell decidualization antigen processing and presentation of peptide antigen proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process elastin catabolic process collagen-containing extracellular matrix regulation of actin cytoskeleton reorganization	04142 04145 04612 05323
TC0700003988.mm.2	Rrp8	ribosomal RNA processing 8	7	-105731729, -105731729	NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799	101867	23	rDNA heterochromatin assembly rDNA heterochromatin assembly nucleus nucleoplasm chromatin silencing complex chromatin silencing complex nucleolus nucleolus cytosol plasma membrane chromatin organization rRNA processing methyltransferase activity transferase activity methylation rDNA heterochromatin rDNA heterochromatin methylated histone binding methylated histone binding cellular response to glucose starvation cellular response to glucose starvation regulation of transcription by glucose regulation of transcription by glucose positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator
TC0700004665.mm.2	Vkorc1	vitamin K epoxide reductase complex, subunit 1	7	-127893062	NM_178600, BC031732 NM_178600, BC031732	27973	34	endoplasmic reticulum blood coagulation blood coagulation blood coagulation response to organonitrogen compound response to organic cyclic compound membrane integral component of membrane oxidoreductase activity drug metabolic process peptidyl-glutamic acid carboxylation peptidyl-glutamic acid carboxylation regulation of blood coagulation vitamin K biosynthetic process vitamin K metabolic process vitamin K metabolic process vitamin K metabolic process vitamin K metabolic process intracellular membrane-bounded organelle response to antibiotic vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-insensitive) activity quinone binding positive regulation of coagulation bone development
TC0800003162.mm.2	Nup133	nucleoporin 133	8	-123897122	NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845	234865	23	chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome outer kinetochore transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore nuclear pore nuclear pore chromosome mRNA export from nucleus mRNA export from nucleus protein import into nucleus nuclear pore organization protein transport poly(A)+ mRNA export from nucleus structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore neural tube development neurogenesis nuclear pore outer ring nuclear pore outer ring nuclear membrane paraxial mesoderm development mRNA transport somite development nephron development	03013
TC0600001404.mm.2	Clec4d	C-type lectin domain family 4, member d	6	123262106	NM_001163161, NM_010819, BC099471 NM_001163161, NM_010819, BC099471 NM_001163161, NM_010819, BC099471	17474	34	adaptive immune response T cell differentiation involved in immune response immune system process plasma membrane membrane integral component of membrane carbohydrate binding positive regulation of myeloid dendritic cell activation immunoglobulin receptor binding Fc-gamma receptor signaling pathway defense response to bacterium innate immune response metal ion binding
TC0200002232.mm.2	Gins1	GINS complex subunit 1 (Psf1 homolog)	2	150909593, 150909593	NM_001163476, NM_027014, BC027537 NM_001163476, NM_027014, BC027537 NM_001163476, NM_027014, BC027537	69270	20	GINS complex inner cell mass cell proliferation protein binding nucleus nucleus chromosome cytoplasm cytoplasm DNA replication DNA strand elongation involved in mitotic DNA replication
TC0X00003301.mm.2	Reps2	RALBP1 associated Eps domain containing protein 2	X	-162411951, -162411951	NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500	194590	19	molecular_function calcium ion binding cytoplasm plasma membrane endocytosis endosomal transport metal ion binding
TC0200005349.mm.2					NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process
TC0500001548.mm.2	Gtf2ird2	GTF2I repeat domain containing 2	5	134184037	NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159	114674	18	DNA binding protein binding nucleus nucleus transition between fast and slow fiber
TC1800001741.mm.2					NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188			molecular_function calcium ion binding protein binding plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cell-cell junction cell-cell junction cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules biological_process endosome to lysosome transport membrane integral component of membrane calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules growth cone synapse organization lipid tube assembly involved in organelle fusion
TC0100003027.mm.2	Dars	aspartyl-tRNA synthetase	1	-128412117, -128363706	NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638	226414	31	nucleotide binding nucleic acid binding RNA binding aminoacyl-tRNA ligase activity aspartate-tRNA ligase activity aspartate-tRNA ligase activity ATP binding cytoplasm cytosol cytosol translation tRNA aminoacylation for protein translation aspartyl-tRNA aminoacylation aspartyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex synapse	00970
TC0900001056.mm.2	Cd109	CD109 antigen	9	78615545	NM_153098, BC052443, CD109 NM_153098, BC052443, CD109 NM_153098, BC052443, CD109	235505	36	negative regulation of protein phosphorylation hair follicle development endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular region extracellular space cytosol plasma membrane negative regulation of peptidase activity negative regulation of keratinocyte proliferation membrane peptidase inhibitor activity negative regulation of transforming growth factor beta receptor signaling pathway anchored component of membrane regulation of keratinocyte differentiation transforming growth factor beta binding negative regulation of wound healing osteoclast fusion
TC1300000763.mm.2					NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907			RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding aminopeptidase activity nucleus nucleolus nucleolus cytoplasm proteolysis cell aging sensory perception of sound peptidase activity metallopeptidase activity zinc ion binding positive regulation of cell population proliferation response to bacterium regulation of gene expression negative regulation of gene expression Wnt signaling pathway hydrolase activity myelination regulation of viral genome replication regulation of viral genome replication positive regulation of angiogenesis metal ion binding long-term synaptic potentiation retina vasculature development in camera-type eye metalloaminopeptidase activity cellular response to lipopolysaccharide cellular response to inorganic substance cellular response to forskolin cellular response to leukemia inhibitory factor regulation of semaphorin-plexin signaling pathway
TC0800003037.mm.2	Gins2	GINS complex subunit 2 (Psf2 homolog)	8	-120581265	NM_178856, BC082565 NM_178856, BC082565	272551	19	double-strand break repair via break-induced replication GINS complex nucleus chromosome DNA replication
TC1100003397.mm.2	Ccl9	chemokine (C-C motif) ligand 9	11	-83572916	NM_011338, BC139318, BC145962 NM_011338, BC139318, BC145962 NM_011338, BC139318, BC145962	20308	52	monocyte chemotaxis cytokine activity extracellular region extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity neutrophil chemotaxis positive regulation of GTPase activity negative regulation of myoblast differentiation CCR chemokine receptor binding lymphocyte chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor	04060 04062
TC0800002558.mm.2					NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97			transmembrane signaling receptor activity G protein-coupled receptor activity calcium ion binding extracellular region plasma membrane integral component of plasma membrane cell adhesion signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway external side of plasma membrane membrane integral component of membrane positive regulation of synapse assembly
TC0200000393.mm.2	Pnpla7	patatin-like phospholipase domain containing 7	2	24976032	NM_146251, BC141365, BC141366 NM_146251, BC141365, BC141366 NM_146251, BC141365, BC141366	241274	25	lysophospholipase activity lysophospholipase activity lysophospholipase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid droplet lipid metabolic process membrane integral component of membrane lipid catabolic process hydrolase activity phosphatidylcholine catabolic process carboxylic ester hydrolase activity
TC1100001730.mm.2	Itgb3	integrin beta 3	11	104607999	NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520	16416	424	positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion fibronectin binding fibronectin binding protease binding positive regulation of leukocyte migration protein disulfide isomerase activity protein kinase C binding integrin binding integrin binding integrin binding protein binding nucleus nucleoplasm plasma membrane cell-cell junction focal adhesion focal adhesion focal adhesion cell-substrate junction assembly cell adhesion cell-matrix adhesion cell-matrix adhesion cell-matrix adhesion integrin-mediated signaling pathway regulation of G protein-coupled receptor signaling pathway integrin complex integrin complex external side of plasma membrane cell surface cell surface cell surface positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of macrophage derived foam cell differentiation positive regulation of fibroblast migration positive regulation of fibroblast migration negative regulation of lipid storage smooth muscle cell migration positive regulation of smooth muscle cell migration membrane integral component of membrane apical plasma membrane apical plasma membrane cell migration fibroblast growth factor binding enzyme binding enzyme binding C-X3-C chemokine binding cell junction platelet activation regulation of cell migration positive regulation of cell migration lamellipodium membrane filopodium membrane microvillus membrane cell-substrate adhesion insulin-like growth factor I binding activation of protein kinase activity negative regulation of lipid transport ruffle membrane regulation of protein localization regulation of actin cytoskeleton organization protein-containing complex cell adhesion mediated by integrin cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading integrin alpha9-beta1 complex integrin alphav-beta3 complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-IGF-1-IGF1R complex alphav-beta3 integrin-HMGB1 complex cellular response to platelet-derived growth factor stimulus apolipoprotein A-I-mediated signaling pathway neuregulin binding melanosome identical protein binding cell projection vascular endothelial growth factor receptor 2 binding receptor complex apoptotic cell clearance apoptotic cell clearance synapse postsynaptic membrane positive regulation of osteoclast differentiation positive regulation of angiogenesis positive regulation of bone resorption positive regulation of bone resorption viral entry into host cell platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation cell projection morphogenesis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process cell adhesion molecule binding extracellular matrix binding negative chemotaxis regulation of release of sequestered calcium ion into cytosol regulation of serotonin uptake negative regulation of cell death regulation of protein tyrosine kinase activity fibrinogen binding fibrinogen binding positive regulation of ERK1 and ERK2 cascade platelet aggregation alpha9-beta1 integrin-ADAM8 complex positive regulation of glomerular mesangial cell proliferation glutamatergic synapse glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization integral component of synaptic membrane positive regulation of substrate adhesion-dependent cell spreading positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway regulation of extracellular matrix organization negative regulation of low-density lipoprotein receptor activity positive regulation of T cell migration	04145 04380 04510 04512 04640 04810 05410 05412 05414
TC0200002395.mm.2	Epb41l1	erythrocyte membrane protein band 4.1 like 1	2	156475533, 156420908, 156421090, 156475548	NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815	13821	50	actin binding signaling receptor binding structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane plasma membrane cytoskeletal protein binding postsynaptic density cortical actin cytoskeleton organization actomyosin structure organization protein-containing complex synaptic membrane	04530
TC0500000850.mm.2	Cxcl2	chemokine (C-X-C motif) ligand 2	5	90903898	NM_009140, BC119511, BC119512 NM_009140, BC119511, BC119512 NM_009140, BC119511, BC119512	20310	162	response to molecule of bacterial origin cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis killing of cells of other organism CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway neuron death cellular response to lipopolysaccharide	04060 04062 04621
TC1100001741.mm.2	Mettl2	methyltransferase like 2	11	105126424	NM_172567, BC089591 NM_172567, BC089591	52686	23	cellular_component tRNA processing methyltransferase activity transferase activity tRNA methylation tRNA methylation methylation tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity	00340 00350
TC0X00001382.mm.2	Prps1	phosphoribosyl pyrophosphate synthetase 1	X	140456602	NM_021463, BC054772 NM_021463, BC054772	19139	35	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleobase metabolic process purine nucleotide biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex urate biosynthetic process identical protein binding protein homodimerization activity ADP binding cellular biosynthetic process hypoxanthine biosynthetic process metal ion binding	00030 00230 01100
TC0500001576.mm.2	Tbl2	transducin (beta)-like 2	5	135149685	NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185	27368	25	endoplasmic reticulum protein kinase binding endoplasmic reticulum unfolded protein response translation initiation factor binding cellular response to glucose starvation phosphoprotein binding cellular response to hypoxia
TC1100001882.mm.2	Cd300a	CD300A molecule	11	114890040	NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A	217303	31	phosphatidylserine binding immune system process serotonin secretion by mast cell transmembrane signaling receptor activity protein binding plasma membrane plasma membrane receptor-mediated endocytosis phosphatidylethanolamine binding negative regulation of serotonin secretion membrane integral component of membrane phosphatase binding negative regulation of B cell proliferation positive regulation of phosphoprotein phosphatase activity negative regulation of mast cell activation involved in immune response negative regulation of MyD88-dependent toll-like receptor signaling pathway signaling receptor activity negative regulation of mast cell degranulation negative regulation of mast cell degranulation negative regulation of MAP kinase activity negative regulation of fibroblast proliferation regulation of T cell receptor signaling pathway negative regulation of B cell receptor signaling pathway negative regulation of NK T cell activation negative regulation of phagocytosis, engulfment negative regulation of neutrophil activation negative regulation of eosinophil activation negative regulation of activation of Janus kinase activity negative regulation of eosinophil migration
TC0700003831.mm.2	P2ry2	purinergic receptor P2Y, G-protein coupled 2	7	-100996567, -100996567	NM_008773, BC006613 NM_008773, BC006613	18442	136	G protein-coupled receptor activity ATP binding mitochondrion lysosome early endosome plasma membrane signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of neuron projection development positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain negative regulation of ossification A1 adenosine receptor binding positive regulation of prostaglandin secretion positive regulation of chemokine production G protein-coupled purinergic nucleotide receptor activity G protein-coupled UTP receptor activity positive regulation of penile erection positive regulation of mucus secretion blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis	04080
TC1500000002.mm.2	Selenop	selenoprotein P	15	3270766, 3270976, 3270810	NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991	20363	74	selenium compound metabolic process selenium compound metabolic process selenium compound metabolic process protein binding extracellular region extracellular region extracellular space brain development locomotory behavior selenium binding selenium binding post-embryonic development sexual reproduction regulation of growth
TC0800000621.mm.2	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	8	56294551	NM_008278, BC021157 NM_008278, BC021157	15446	43	prostaglandin E receptor activity extracellular space nucleoplasm cytoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy female pregnancy parturition basolateral plasma membrane 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding positive regulation of apoptotic process response to ethanol negative regulation of cell cycle NAD binding NAD+ binding ductus arteriosus closure positive regulation of vascular associated smooth muscle cell proliferation regulation of prostaglandin catabolic process
TC1100000995.mm.2	Mybbp1a	MYB binding protein (P160) 1a	11	72441326	NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889	18432	63	DNA binding transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleolus nucleolus nucleolus cytoplasm regulation of transcription, DNA-templated transcription factor binding zinc ion binding respiratory electron transport chain circadian regulation of gene expression cellular response to glucose starvation ribosome biogenesis NLS-dependent protein nuclear import complex intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding negative regulation of transcription, DNA-templated rhythmic process E-box binding positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of anoikis
TC1300002036.mm.2	Nop16	NOP16 nucleolar protein	13	-54584190	NM_178605, BC012213 NM_178605, BC012213	28126	21	nucleus nucleoplasm nucleolus nucleolus ribosomal large subunit biogenesis intracellular membrane-bounded organelle
TC1900000683.mm.2	Nolc1	nucleolar and coiled-body phosphoprotein 1	19	46075846	NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086	70769	29	protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm nucleolus organization Cajal body small nuclear ribonucleoprotein complex
TC0400000207.mm.2	Mms22l	MMS22-like, DNA repair protein	4	24496450	NM_199467, BC137910, BC145028 NM_199467, BC137910, BC145028 NM_199467, BC137910, BC145028	212377	19	double-strand break repair via homologous recombination double-strand break repair via homologous recombination molecular_function nucleus nucleoplasm cytosol DNA repair cellular response to DNA damage stimulus replication fork processing replication fork processing FACT complex MCM complex MCM complex nuclear replication fork nuclear replication fork
TC1200000132.mm.2	E2f6	E2F transcription factor 6	12	16810964	NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F	50496	48	regulation of transcription involved in G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleoplasm DNA replication factor A complex transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle protein dimerization activity MLL1 complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex
TC0800001116.mm.2	Arl2bp	ADP-ribosylation factor-like 2 binding protein	8	94667090, 94666599	NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708	107566	23	transcription coactivator activity protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space centrosome cytoskeleton cilium midbody GTPase regulator activity positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein cell projection maintenance of protein location in nucleus maintenance of protein location in nucleus
TC1400002259.mm.2	Elp3	elongator acetyltransferase complex subunit 3	14	-65530445	NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453	74195	39	tRNA binding neuron migration tRNA wobble uridine modification tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation RNA binding catalytic activity nucleus nucleolus cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II nervous system development central nervous system development tRNA processing phosphorylase kinase regulator activity acetyltransferase activity transferase activity transferase activity, transferring acyl groups positive regulation of cell migration elongator holoenzyme complex elongator holoenzyme complex metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding
TC1100001049.mm.2	Mettl16	methyltransferase like 16	11	74770862	NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724	67493	23	RNA methylation mRNA (N6-adenosine)-methyltransferase activity mRNA (N6-adenosine)-methyltransferase activity RNA binding nucleus nucleus cytoplasm mRNA catabolic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process methyltransferase activity posttranscriptional regulation of gene expression posttranscriptional regulation of gene expression transferase activity U6 snRNA 3'-end binding methylation RNA stem-loop binding 23S rRNA (adenine(1618)-N(6))-methyltransferase activity mRNA destabilization rRNA base methylation mRNA methylation mRNA methylation U6 snRNA (adenine-(43)-N(6))-methyltransferase activity snRNA (adenine-N6)-methylation negative regulation of 3'-UTR-mediated mRNA stabilization
TC0500000260.mm.2	Insig1	insulin induced gene 1	5	28071411	NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499	231070	37	protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lipid metabolic process triglyceride metabolic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process response to sterol depletion oxysterol binding steroid metabolic process cholesterol metabolic process lipid binding negative regulation of steroid biosynthetic process membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process cellular response to insulin stimulus SREBP signaling pathway SREBP signaling pathway SREBP-SCAP-Insig complex SREBP-SCAP-Insig complex cellular response to sterol SREBP-SCAP complex retention in endoplasmic reticulum SREBP-SCAP complex retention in endoplasmic reticulum inner ear morphogenesis middle ear morphogenesis cholesterol homeostasis negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process roof of mouth development cranial suture morphogenesis negative regulation of protein exit from endoplasmic reticulum negative regulation of cargo loading into COPII-coated vesicle
TC0500000494.mm.2	Ncapg	non-SMC condensin I complex, subunit G	5	45669924	NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960	54392	26	condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex molecular_function cytoplasm cytoplasm mitotic chromosome condensation mitotic chromosome condensation
TC1900000529.mm.2	Kif11	kinesin family member 11	19	37376381	NM_010615, BC060670 NM_010615, BC060670	16551	58	nucleotide binding spindle pole microtubule motor activity ATP binding nucleus cytoplasm spindle cytosol cytoskeleton microtubule spindle microtubule spindle microtubule microtubule-based movement cell cycle spindle organization mitotic centrosome separation microtubule binding ATP-dependent microtubule motor activity, plus-end-directed protein kinase binding protein-containing complex regulation of mitotic centrosome separation spindle assembly cell division mitotic spindle mitotic spindle assembly mitotic spindle assembly
TC1400002515.mm.2	Diaph3	diaphanous related formin 3	14	-86655356	NM_019670, BC028920, BC085191 NM_019670, BC028920, BC085191 NM_019670, BC028920, BC085191	56419	64	actin binding protein binding nucleus nucleus cytoplasm cytoplasm cytoskeleton organization cellular component organization actin cytoskeleton organization actin filament polymerization small GTPase binding	04810
TC1000002003.mm.2	Amd2	S-adenosylmethionine decarboxylase 2	10	-40287464	NM_007444	100041585	17	adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity cytosol cytosol polyamine biosynthetic process spermine biosynthetic process spermidine biosynthetic process lyase activity carboxy-lyase activity putrescine binding putrescine binding identical protein binding
TC1300001641.mm.2	Hfe	homeostatic iron regulator	13	-23702033	NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746	15216	179	negative regulation of T cell antigen processing and presentation negative regulation of T cell cytokine production signaling receptor binding extracellular space extracellular space nucleoplasm early endosome plasma membrane ion transport cellular iron ion homeostasis external side of plasma membrane external side of plasma membrane response to iron ion positive regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral component of membrane BMP signaling pathway beta-2-microglobulin binding cytoplasmic vesicle positive regulation of protein binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of iron ion transport regulation of iron ion transport co-receptor binding hormone biosynthetic process apical part of cell basal part of cell positive regulation of receptor-mediated endocytosis perinuclear region of cytoplasm recycling endosome iron ion homeostasis iron ion homeostasis multicellular organismal iron ion homeostasis cellular response to iron ion positive regulation of peptide hormone secretion iron ion import across plasma membrane negative regulation of receptor binding positive regulation of receptor binding negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I positive regulation of ferrous iron binding positive regulation of transferrin receptor binding terminal web transferrin receptor binding transferrin receptor binding transferrin receptor binding response to iron ion starvation HFE-transferrin receptor complex HFE-transferrin receptor complex regulation of protein localization to cell surface negative regulation of ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process negative regulation of signaling receptor activity positive regulation of signaling receptor activity negative regulation of CD8-positive, alpha-beta T cell activation
TC0200000492.mm.2	Ak8	adenylate kinase 8	2	28700160	NM_001033874, BC100481, BC109352 NM_001033874, BC100481, BC109352 NM_001033874, BC100481, BC109352	68870	19	nucleotide binding adenylate kinase activity adenylate kinase activity cytidylate kinase activity cytidylate kinase activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding cytoplasm axoneme nucleobase-containing compound metabolic process nucleoside diphosphate phosphorylation nucleoside diphosphate phosphorylation nucleoside triphosphate biosynthetic process nucleoside triphosphate biosynthetic process kinase activity phosphorylation transferase activity nucleobase-containing compound kinase activity ventricular system development sperm flagellum
TC0300001247.mm.2	Bcar3	breast cancer anti-estrogen resistance 3	3	122483568, 122419756	NM_013867, BC023930 NM_013867, BC023930	29815	26	phosphotyrosine residue binding lens morphogenesis in camera-type eye guanyl-nucleotide exchange factor activity cytoplasm focal adhesion signal transduction small GTPase mediated signal transduction insulin receptor signaling pathway membrane kinase binding cell junction positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation of DNA replication positive regulation of epidermal growth factor receptor signaling pathway endothelin receptor signaling pathway
TC1200000334.mm.2	Agmo	alkylglycerol monooxygenase	12	37241638	NM_178767, BC148840 NM_178767, BC148840	319660	14	iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process membrane lipid metabolic process lipid biosynthetic process membrane integral component of membrane oxidoreductase activity ether lipid metabolic process glyceryl-ether monooxygenase activity glyceryl-ether monooxygenase activity
TC0700002980.mm.2	Prmt1	protein arginine N-methyltransferase 1	7	-44976754	NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964	15469	104	in utero embryonic development protein binding nucleus nucleus cytoplasm cytosol protein methylation methyltransferase activity N-methyltransferase activity protein methyltransferase activity protein methyltransferase activity positive regulation of cell population proliferation methyl-CpG binding histone-arginine N-methyltransferase activity membrane protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity [cytochrome c]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation enzyme binding peptidyl-arginine methylation, to asymmetrical-dimethyl arginine peptidyl-arginine methylation, to asymmetrical-dimethyl arginine snoRNP binding neuron projection development methylation protein-containing complex methylosome protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity peptidyl-arginine omega-N-methylation histone methyltransferase activity histone methyltransferase activity identical protein binding histone H4-R3 methylation histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) positive regulation of erythrocyte differentiation regulation of megakaryocyte differentiation negative regulation of megakaryocyte differentiation positive regulation of hemoglobin biosynthetic process mitogen-activated protein kinase p38 binding protein homooligomerization positive regulation of p38MAPK cascade S-adenosyl-L-methionine binding
TC1700002541.mm.2	Fam98a	family with sequence similarity 98, member A	17	-75537084, -75537085	NM_133747, BC004626 NM_133747, BC004626	72722	26	protein binding protein methylation protein methyltransferase activity positive regulation of cell population proliferation positive regulation of gene expression lysosome localization tRNA-splicing ligase complex positive regulation of ruffle assembly
TC0700002168.mm.2	Tmem150b	transmembrane protein 150B	7	-4716001, -4706831	NM_001142792, NM_177887, BC022651 NM_001142792, NM_177887, BC022651 NM_001142792, NM_177887, BC022651	330460	13	molecular_function lysosome endosome plasma membrane integral component of plasma membrane autophagy regulation of autophagy membrane integral component of membrane cytoplasmic vesicle
TC0400000085.mm.2	Ccne2	cyclin E2	4	11191708, 11191350	NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727	12448	79	regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex telomere maintenance nucleus cytoplasm centrosome DNA replication initiation cell cycle homologous chromosome pairing at meiosis cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding mitotic cell cycle phase transition cell division regulation of cell cycle chromosome organization involved in meiotic cell cycle cyclin E1-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex regulation of cellular protein localization	04110 04114 04115 05200 05215 05222
TC0300001364.mm.2	Cenpe	centromere protein E	3	135212562	NM_173762	229841	44	nucleotide binding mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed chromosome outer kinetochore microtubule motor activity ATP binding nucleus nucleoplasm chromosome cytoplasm kinetochore microtubule cytosol cytoskeleton microtubule microtubule microtubule-based movement cell cycle mitotic spindle organization spindle assembly involved in female meiosis I chromosome segregation mitotic chromosome movement towards spindle pole mitotic metaphase plate congression regulation of mitotic nuclear division mitotic spindle assembly checkpoint multicellular organism development microtubule binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed attachment of spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore microtubule cytoskeleton protein kinase binding regulation of mitotic metaphase/anaphase transition midbody regulation of protein stability kinetochore binding kinetochore binding establishment of protein localization positive regulation of mitotic metaphase/anaphase transition positive regulation of protein kinase activity positive regulation of protein kinase activity regulation of developmental process spindle midzone cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore kinetochore assembly positive regulation of chromosome segregation positive regulation of attachment of spindle microtubules to kinetochore microtubule plus-end directed mitotic chromosome migration lateral attachment of mitotic spindle microtubules to kinetochore mitotic spindle midzone
TC0200002010.mm.2	Cdc25b	cell division cycle 25B	2	131186947	NM_001111075, NM_023117, BC057568 NM_001111075, NM_023117, BC057568 NM_001111075, NM_023117, BC057568	12531	69	G2/M transition of mitotic cell cycle mitotic cell cycle spindle pole oocyte maturation phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm centrosome cytoskeleton protein phosphorylation protein dephosphorylation cell cycle female meiosis I positive regulation of G2/M transition of mitotic cell cycle hydrolase activity protein kinase binding positive regulation of cytokinesis positive regulation of protein kinase activity positive regulation of mitotic cell cycle cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition	04010 04110 04914
TC0200000591.mm.2	Sh2d3c	SH2 domain containing 3C	2	32721054, 32727688	NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203	27387	25	transmembrane receptor protein tyrosine kinase adaptor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm plasma membrane signal transduction small GTPase mediated signal transduction membrane positive regulation of peptidyl-serine phosphorylation cell projection
TC1700000402.mm.2	Pgap6	post-glycosylphosphatidylinositol attachment to proteins 6	17	26113315	NM_021793, BC005722 NM_021793, BC005722	60455	20	molecular_function phospholipase A2 activity lysosome plasma membrane integral component of plasma membrane biological_process membrane integral component of membrane hydrolase activity
TC0100000456.mm.2	Nop58	NOP58 ribonucleoprotein	1	59685005	NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135	55989	31	TFIID-class transcription factor complex binding fibrillar center nucleus nucleoplasm nucleolus sno(s)RNA-containing ribonucleoprotein complex cytosol Cajal body snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis snoRNA localization ATPase binding pre-snoRNP complex	03008
TC0100001877.mm.2	Plxna2	plexin A2	1	194619828	NM_008882, BC068155 NM_008882, BC068155	18845	130	somitogenesis semaphorin receptor complex protein binding plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane negative regulation of cell adhesion signal transduction cell surface receptor signaling pathway regulation of cell shape membrane integral component of membrane semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity neural tube development cerebellar granule cell precursor tangential migration regulation of cell migration regulation of cell migration identical protein binding regulation of GTPase activity positive regulation of axonogenesis centrosome localization pharyngeal system development limb bud formation collagen-containing extracellular matrix semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway involved in axon guidance	04360
TC1800000509.mm.2	Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	18	50128200	NM_008292, BC022175 NM_008292, BC022175	15488	55	very long-chain fatty acid metabolic process 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity enoyl-CoA hydratase activity enoyl-CoA hydratase activity estradiol 17-beta-dehydrogenase activity protein binding mitochondrion peroxisome peroxisome peroxisome peroxisomal matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation androgen metabolic process estrogen metabolic process oxidoreductase activity long-chain-enoyl-CoA hydratase activity lyase activity isomerase activity 3-hydroxyacyl-CoA dehydratase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity very long-chain fatty-acyl-CoA metabolic process medium-chain fatty-acyl-CoA metabolic process identical protein binding protein homodimerization activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Sertoli cell development	00120 01100 04146
TC0200001006.mm.2	Dhrs9	dehydrogenase/reductase (SDR family) member 9	2	69380461	NM_175512, BC118029 NM_175512, BC118029	241452	16	retinoic acid biosynthetic process alcohol dehydrogenase (NAD+) activity retinol dehydrogenase activity endoplasmic reticulum lipid metabolic process steroid metabolic process androgen metabolic process membrane oxidoreductase activity integral component of endoplasmic reticulum membrane progesterone metabolic process 9-cis-retinoic acid biosynthetic process intracellular membrane-bounded organelle androsterone dehydrogenase activity testosterone dehydrogenase (NAD+) activity androstan-3-alpha,17-beta-diol dehydrogenase activity	00830 01100
TC0200004547.mm.2	Ncaph	non-SMC condensin I complex, subunit H	2	-127103809	NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060	215387	31	condensin complex condensin complex condensin complex condensin complex chromatin binding chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation female meiotic nuclear division meiotic chromosome condensation meiotic chromosome condensation chromosome condensation DNA topoisomerase binding meiotic chromosome segregation cell division female meiosis chromosome separation DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity
TC1500000659.mm.2	Nol12	nucleolar protein 12	15	78934932	NM_133800, BC013701, BC094424 NM_133800, BC013701, BC094424 NM_133800, BC013701, BC094424	97961	20	single-stranded DNA binding RNA binding RNA binding nucleus nucleolus nucleolus nucleolus rRNA binding identical protein binding
TC1700001881.mm.2	Kifc1	kinesin family member C1	17	-33875665	NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328	100502766	35	microtubule motor activity microtubule motor activity protein binding nucleus nucleus microtubule organizing center kinesin complex kinesin complex microtubule microtubule-based movement microtubule binding ATP-dependent microtubule motor activity, minus-end-directed negative regulation of centrosome duplication ATPase activity endocytic vesicle spindle pole centrosome vesicle transport along microtubule minus-end-directed vesicle transport along microtubule mitotic spindle mitotic spindle mitotic spindle assembly
TC0300000902.mm.2	Ctsk	cathepsin K	3	95499209	NM_007802, BC046320 NM_007802, BC046320	13038	199	fibronectin binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity collagen binding extracellular region extracellular space extracellular space extracellular space nucleoplasm cytoplasm lysosome lysosome lysosome plasma membrane proteolysis thyroid hormone generation thyroid hormone generation immune response peptidase activity cysteine-type peptidase activity external side of plasma membrane membrane hydrolase activity collagen catabolic process collagen catabolic process intracellular membrane-bounded organelle proteoglycan binding bone resorption bone resorption proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process negative regulation of cartilage development	04142 04380 04620 05323
TC1100002549.mm.2	Hmmr	hyaluronan mediated motility receptor (RHAMM)	11	-40701387	NM_013552, BC021427 NM_013552, BC021427	15366	47	hyaluronic acid binding cytoplasm centrosome cytosol microtubule cytoskeleton	04512
TC0400002110.mm.2	Noc2l	NOC2 like nucleolar associated transcriptional repressor	4	156236014, 156236009	NM_021303, BC020013 NM_021303, BC020013	57741	25	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II p53 binding negative regulation of B cell apoptotic process chromatin binding transcription corepressor activity transcription corepressor activity nucleus nucleus nucleoplasm nucleoplasm chromosome nucleolus nucleolus cytosol apoptotic process Noc1p-Noc2p complex Noc2p-Noc3p complex nucleosome binding nucleosomal histone binding chromatin assembly cellular response to UV negative regulation of histone acetylation negative regulation of histone acetylation negative regulation of histone acetylation ribosomal large subunit biogenesis histone binding histone binding histone binding repressing transcription factor binding repressing transcription factor binding negative regulation of intrinsic apoptotic signaling pathway
TC1000000752.mm.2	Slc19a1	solute carrier family 19 (folate transporter), member 1	10	77033211, 77032738	NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263	20509	60	folic acid binding folic acid binding plasma membrane plasma membrane integral component of plasma membrane organic anion transmembrane transporter activity folic acid transmembrane transporter activity folic acid transmembrane transporter activity folate:anion antiporter activity folate:anion antiporter activity antiporter activity methotrexate transmembrane transporter activity methotrexate transmembrane transporter activity organic anion transport folic acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane brush border membrane vitamin transport methotrexate transport methotrexate transport transmembrane transport cyclic-GMP-AMP binding vitamin transmembrane transporter activity folate transmembrane transport folate transmembrane transport folate transmembrane transport folate import across plasma membrane folate import across plasma membrane	04977
TC0500001798.mm.2	Gtf3a	general transcription factor III A	5	146948656	NM_025652, BC032292 NM_025652, BC032292	66596	24	RNA polymerase III general transcription initiation factor activity nucleic acid binding DNA binding DNA binding RNA binding nucleus nucleoplasm 5S rRNA binding ribosome biogenesis ribosomal large subunit biogenesis metal ion binding
TC0600003074.mm.2	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	6	-122727808	NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811	20527	133	acrosomal membrane transporter activity glucose transmembrane transporter activity glucose binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane integral component of plasma membrane caveola carbohydrate transport monosaccharide transmembrane transporter activity membrane integral component of membrane galactoside binding kinase binding transmembrane transporter activity synaptic vesicle membrane xylose binding dehydroascorbic acid transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity cell projection D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity transmembrane transport dehydroascorbic acid transport glucose import across plasma membrane glutamatergic synapse integral component of synaptic membrane transport across blood-brain barrier glucose transmembrane transport glucose transmembrane transport glucose transmembrane transport
TC1800000708.mm.2	Psmg2	proteasome (prosome, macropain) assembly chaperone 2	18	67641586	NM_134138, BC016606 NM_134138, BC016606	107047	21	nucleus nucleus cytosol mitotic spindle assembly checkpoint negative regulation of apoptotic process proteasome assembly chaperone-mediated protein complex assembly regulation of cell cycle molecular adaptor activity chaperone complex
TC0700004361.mm.2					NM_145590, NR_037290, BC017158 NM_145590, NR_037290, BC017158 NM_145590, NR_037290, BC017158			molecular_function biological_process membrane integral component of membrane
TC1900001217.mm.2	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	19	-17326140, -17326140, -17326140	NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126	14537	68	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity extracellular space Golgi apparatus trans-Golgi network acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity glycoprotein biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups Golgi cisterna tissue morphogenesis leukocyte tethering or rolling cell adhesion molecule production kidney morphogenesis	00512 01100
TC0300002357.mm.2	Il6ra	interleukin 6 receptor, alpha	3	-89869323	NM_010559	16194	145	cytokine receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity interleukin-6 receptor binding extracellular region extracellular space plasma membrane interleukin-6 receptor complex interleukin-6 receptor complex positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of activation of Janus kinase activity positive regulation of activation of Janus kinase activity vascular endothelial growth factor production membrane integral component of membrane apical plasma membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway enzyme binding cytokine binding interleukin-11 binding interleukin-6 binding interleukin-6 binding interleukin-6 binding endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production neuronal cell body membrane negative regulation of collagen biosynthetic process response to cytokine positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein protein homodimerization activity receptor complex positive regulation of MAPK cascade developmental growth positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway positive regulation of glomerular mesangial cell proliferation T-helper 17 cell lineage commitment	04060 04630 04640
TC0200003753.mm.2	Gpr155	G protein-coupled receptor 155	2	-73341505	NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707	68526	13	molecular_function cognition
TC1100003659.mm.2	Plxdc1	plexin domain containing 1	11	-97923236	NM_001163608, NM_028199, BC114352 NM_001163608, NM_028199, BC114352 NM_001163608, NM_028199, BC114352	72324	24	angiogenesis protein binding cytoplasm plasma membrane plasma membrane bicellular tight junction membrane integral component of membrane cell junction dendrite neuronal cell body receptor complex
TC0100003783.mm.2	Cenpf	centromere protein F	1	-189640613	NM_001081363	108000	56	mitotic cell cycle mitotic cell cycle chromosome, centromeric region chromosome, centromeric region spindle pole spindle pole condensed chromosome outer kinetochore kidney development nucleus nucleus nucleus nucleus nuclear envelope nucleoplasm cytoplasm centrosome spindle axoneme chromosome segregation protein C-terminus binding transcription factor binding regulation of G2/M transition of mitotic cell cycle regulation of G2/M transition of mitotic cell cycle protein transport regulation of striated muscle tissue development nuclear matrix ventricular system development midbody ciliary basal body protein homodimerization activity pronucleus negative regulation of transcription, DNA-templated metaphase plate congression metaphase plate congression dynein complex binding dynein complex binding ciliary transition fiber ciliary transition fiber
TC0500002232.mm.2	Zfyve28	zinc finger, FYVE domain containing 28	5	-34194893	NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051	231125	20	cytoplasm endosome cytosol negative regulation of epidermal growth factor-activated receptor activity negative regulation of epidermal growth factor-activated receptor activity membrane early endosome membrane early endosome membrane phosphatidylinositol-3-phosphate binding negative regulation of epidermal growth factor receptor signaling pathway metal ion binding
TC1100001156.mm.2	Aldoc	aldolase C, fructose-bisphosphate	11	78324197, 78323072	NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184	11676	84	catalytic activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity cytoplasm mitochondrion cytosol glycolytic process apoptotic process aging cytoskeletal protein binding lyase activity fructose 1,6-bisphosphate metabolic process fructose 1,6-bisphosphate metabolic process axon identical protein binding protein-containing complex binding postsynaptic cytosol	00010 00030 00051 01100
TC1500001933.mm.2	Polr3h	polymerase (RNA) III (DNA directed) polypeptide H	15	-81915029	NM_030229, BC010793 NM_030229, BC010793	78929	23	immune system process DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex centrosome nucleobase-containing compound metabolic process transcription, DNA-templated transcription by RNA polymerase III transcription initiation from RNA polymerase III promoter intracellular membrane-bounded organelle innate immune response defense response to virus	00230 00240 01100 03020 04623
TC1500001005.mm.2	Troap	trophinin associated protein	15	99074972	NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227	78733	12	molecular_function cellular_component cytoplasm cell adhesion biological_process
TC1100001849.mm.2	Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	11	111066163	NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842	16518	120	inward rectifier potassium channel activity inward rectifier potassium channel activity voltage-gated ion channel activity protein binding phosphatidylinositol-4,5-bisphosphate binding smooth endoplasmic reticulum rough endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane ion transport potassium ion transport voltage-gated potassium channel complex intercalated disc regulation of skeletal muscle contraction via regulation of action potential magnesium ion transport membrane integral component of membrane T-tubule dendrite intrinsic component of membrane regulation of ion transmembrane transport identical protein binding identical protein binding neuronal cell body dendritic spine protein homotetramerization relaxation of cardiac muscle regulation of membrane repolarization potassium ion transmembrane transport cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction regulation of cardiac muscle cell contraction voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential regulation of heart rate by cardiac conduction relaxation of skeletal muscle positive regulation of potassium ion transmembrane transport potassium ion import across plasma membrane potassium ion import across plasma membrane	04971
TC0X00002671.mm.2	Las1l	LAS1-like (S. cerevisiae)	X	-95935312, -95935320	NM_152822, BC141155 NM_152822, BC141155	76130	25	maturation of 5.8S rRNA maturation of LSU-rRNA nucleus cytoplasm rRNA processing preribosome, large subunit precursor MLL1 complex
TC0800003160.mm.2	Ccsap	centriole, cilia and spindle associated protein	8	-123840843, -123839973, -123839973	NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300	73420	14	cytoplasm centrosome centriole centriole spindle spindle cytoskeleton microtubule cilium axoneme axoneme cell cycle multicellular organism development microtubule binding microtubule binding axon axon ciliary transition zone ciliary transition zone ciliary basal body ciliary basal body cell projection cell division mitotic spindle astral microtubule mitotic spindle regulation of mitotic spindle assembly regulation of mitotic spindle assembly mitotic spindle microtubule depolymerization
TC0100003639.mm.2	Adss	adenylosuccinate synthetase, non muscle	1	-177763177	NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417	11566	23	nucleotide binding adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cytoplasm mitochondrion cytosol purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process aspartate metabolic process ligase activity 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding	00230 00250 01100
TC1100001586.mm.2	Cdc6	cell division cycle 6	11	98907800, 98908150	NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434	23834	42	nucleotide binding mitotic cell cycle spindle pole chromatin binding DNA replication origin binding ATP binding nucleus nucleus nucleoplasm cytoplasm spindle cytosol DNA replication DNA replication initiation cell cycle kinase binding regulation of mitotic metaphase/anaphase transition positive regulation of cytokinesis mitotic DNA replication checkpoint intercellular bridge positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of fibroblast proliferation spindle midzone cell division positive regulation of chromosome segregation mitotic spindle	04110
TC0100003279.mm.2	Dhx9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	1	-153455757	NM_007842	13211	54	nucleotide binding alternative mRNA splicing, via spliceosome RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding regulatory region RNA binding regulatory region RNA binding RNA polymerase II transcription factor binding immune system process nucleic acid binding DNA binding DNA helicase activity DNA replication origin binding double-stranded DNA binding single-stranded DNA binding transcription coregulator activity transcription coactivator activity RNA binding RNA binding RNA helicase activity double-stranded RNA binding single-stranded RNA binding mRNA binding helicase activity protein binding ATP binding intracellular anatomical structure nucleus nucleus nucleoplasm perichromatin fibrils nucleolus nucleolus nucleolus cytoplasm cytoplasm centrosome polysome cytoskeleton DNA-templated transcription, termination regulation of transcription by RNA polymerase II mRNA processing regulation of translation inflammatory response circadian rhythm RNA splicing RNA secondary structure unwinding actin cytoskeleton RISC complex nuclear body hydrolase activity ATPase activity targeting of mRNA for destruction involved in RNA interference gene silencing by RNA chromatin DNA binding DNA duplex unwinding positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interleukin-18 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production protein-containing complex 3'-5' DNA/RNA helicase activity 3'-5' RNA helicase activity cellular response to heat cellular protein-containing complex assembly siRNA binding RNA stem-loop binding cytoplasmic ribonucleoprotein granule DNA-templated viral transcription polysomal ribosome 3'-5' DNA helicase activity 3'-5' DNA helicase activity G-quadruplex DNA unwinding innate immune response positive regulation of innate immune response triplex DNA binding positive regulation of DNA repair positive regulation of DNA replication positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of RNA export from nucleus metal ion binding nucleoside-triphosphate diphosphatase activity positive regulation of fibroblast proliferation rhythmic process positive regulation of viral transcription regulation of mRNA processing regulation of mRNA processing regulation of defense response to virus by host positive regulation of inflammatory response mRNA transport positive regulation of NF-kappaB transcription factor activity positive regulation of response to cytokine stimulus importin-alpha family protein binding RNA polymerase binding pyroptosis RISC-loading complex small RNA loading onto RISC CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex cellular response to tumor necrosis factor cellular response to exogenous dsRNA nuclear stress granule protein localization to cytoplasmic stress granule positive regulation of viral translation RISC complex binding polysome binding positive regulation of polysome binding single-stranded 3'-5' DNA helicase activity sequence-specific mRNA binding promoter-specific chromatin binding ribonucleoprotein complex ribonucleoprotein complex positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity positive regulation of gene silencing by miRNA regulation of cytoplasmic translation positive regulation of cytoplasmic translation
TC0100000282.mm.2	Npas2	neuronal PAS domain protein 2	1	39194271	NM_008719, BC109166 NM_008719, BC109166	18143	63	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus circadian rhythm circadian regulation of gene expression circadian regulation of gene expression response to drug circadian sleep/wake cycle regulation of circadian rhythm locomotor rhythm positive regulation of DNA repair positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding protein dimerization activity rhythmic process response to redox state response to redox state Hsp90 protein binding negative regulation of cell death CLOCK-BMAL transcription complex sequence-specific double-stranded DNA binding positive regulation of behavioral fear response regulation of response to DNA damage stimulus	04710
TC1900001691.mm.2	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	19	-55067635, -55067635	NM_008149, BC019201 NM_008149, BC019201	14732	58	regulation of cytokine production glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane glycerol-3-phosphate metabolic process lipid metabolic process fatty acid metabolic process fatty acid metabolic process acyl-CoA metabolic process triglyceride metabolic process glycerophospholipid metabolic process diacylglycerol biosynthetic process phosphatidic acid biosynthetic process phosphatidylglycerol biosynthetic process O-acyltransferase activity phospholipid biosynthetic process response to glucose positive regulation of triglyceride biosynthetic process response to activity membrane integral component of membrane transferase activity transferase activity, transferring acyl groups triglyceride biosynthetic process triglyceride biosynthetic process mitochondrial membrane mitochondrial membrane interleukin-2 production cellular response to insulin stimulus positive regulation of multicellular organism growth positive regulation of activated T cell proliferation cellular lipid metabolic process defense response to virus fatty acid homeostasis phospholipid homeostasis negative regulation of activation-induced cell death of T cells	00561 00564 01100
TC1600001770.mm.2	St3gal6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	16	-58469741, -58469741	NM_018784, BC052338 NM_018784, BC052338	54613	23	Golgi apparatus cellular protein modification process protein glycosylation glycolipid metabolic process sialyltransferase activity sialyltransferase activity oligosaccharide metabolic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups beta-galactoside alpha-2,3-sialyltransferase activity beta-galactoside alpha-2,3-sialyltransferase activity	00601 01100
TC0100000447.mm.2	Cdk15	cyclin-dependent kinase 15	1	59256905	NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036	271697	15	regulation of transcription involved in G1/S transition of mitotic cell cycle nucleotide binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity cyclin binding metal ion binding
TC1700001689.mm.2	Nme4	NME/NM23 nucleoside diphosphate kinase 4	17	-26091744	NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23	56520	24	nucleotide binding nucleoside diphosphate kinase activity ATP binding mitochondrion mitochondrion mitochondrial intermembrane space GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process lipid transport lipid binding nucleotide metabolic process membrane kinase activity phosphorylation transferase activity protein-containing complex binding metal ion binding GTPase binding cardiolipin binding	00230 00240 01100
TC1700002208.mm.2	Bysl	bystin-like	17	-47599330	NM_016859, BC017530 NM_016859, BC017530	53414	24	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) in utero embryonic development blastocyst formation trophectodermal cell differentiation nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm cytoplasmic microtubule rRNA processing cell population proliferation snoRNA binding preribosome, small subunit precursor ribosome biogenesis cell projection intracellular membrane-bounded organelle apical part of cell perinuclear region of cytoplasm
MG-1-pos-10341793_st
TC0X00002266.mm.2					NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271			Golgi membrane cytoplasm endosome early endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus plasma membrane plasma membrane cation transport cobalt ion transport copper ion transport iron ion transport cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity magnesium ion transmembrane transporter activity magnesium ion transport membrane integral component of membrane inorganic cation transmembrane transporter activity inorganic cation transmembrane transporter activity integral component of endoplasmic reticulum membrane membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane EMC complex EMC complex
TC0100000237.mm.2	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	1	36068399	NM_015818, BC052316 NM_015818, BC052316	50785	45	angiogenesis sulfotransferase activity heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, enzymatic modification heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane integral component of membrane transferase activity heparan sulfate 6-O-sulfotransferase activity heparan sulfate 6-O-sulfotransferase activity lung alveolus development neuron development labyrinthine layer blood vessel development	00534
TC1100000892.mm.2	Aurkb	aurora kinase B	11	69045636	NM_011496, BC003261 NM_011496, BC003261	20877	114	negative regulation of transcription by RNA polymerase II nucleotide binding chromosome, centromeric region kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region negative regulation of B cell apoptotic process protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm spindle cytoskeleton spindle microtubule protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle assembly checkpoint chromocenter kinase activity phosphorylation transferase activity kinase binding midbody midbody spindle pole centrosome negative regulation of protein binding chromosome passenger complex chromosome passenger complex chromosome passenger complex positive regulation of telomere maintenance via telomerase regulation of cytokinesis positive regulation of cytokinesis protein localization to kinetochore cellular response to UV histone serine kinase activity histone serine kinase activity cleavage furrow formation histone H3-S28 phosphorylation metal ion binding spindle midzone mitotic spindle midzone assembly cell division positive regulation of telomerase activity mitotic spindle pole mitotic spindle pole positive regulation of telomere capping positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore mitotic spindle midzone
TC0X00001634.mm.2	Phka2	phosphorylase kinase alpha 2	X	160502161, 160502161, 160502161	NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040	110094	27	catalytic activity calmodulin binding plasma membrane phosphorylase kinase complex phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process protein phosphorylation membrane	04020 04910
TC0200003865.mm.2	Calcrl	calcitonin receptor-like	2	-84330626	NM_018782, BC138537, BC138540 NM_018782, BC138537, BC138540 NM_018782, BC138537, BC138540	54598	41	angiogenesis angiogenesis adrenomedullin receptor activity adrenomedullin receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity transmembrane signaling receptor activity G protein-coupled receptor activity calcitonin receptor activity cytoplasm lysosome endosome endoplasmic reticulum plasma membrane plasma membrane calcium ion transport signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway heart development positive regulation of cell population proliferation G protein-coupled peptide receptor activity protein transport membrane integral component of membrane receptor internalization negative regulation of smooth muscle contraction positive regulation of smooth muscle cell proliferation negative regulation of inflammatory response cellular response to sucrose stimulus adrenomedullin receptor complex CGRP receptor complex calcitonin gene-related peptide receptor signaling pathway adrenomedullin binding adrenomedullin receptor signaling pathway	04080 04270
TC0900001099.mm.2	Sh3bgrl2	SH3 domain binding glutamic acid-rich protein like 2	9	83548337	NM_172507, BC038473 NM_172507, BC038473	212531	17	protein binding nucleus nucleoplasm biological_process SH3 domain binding nuclear membrane
TC0900001345.mm.2	Dusp7	dual specificity phosphatase 7	9	106368631	NM_153459, BC010207 NM_153459, BC010207	235584	22	inactivation of MAPK activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity cytoplasm cytosol cytosol protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-threonine dephosphorylation negative regulation of MAP kinase activity mitogen-activated protein kinase binding	04010
TC1400002150.mm.2	Ska3	spindle and kinetochore associated complex subunit 3	14	-57806560	NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501	219114	19	mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore molecular_function chromosome cytoplasm centrosome cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cell cycle chromosome segregation chromosome segregation regulation of microtubule polymerization or depolymerization cell division mitotic spindle
TC0200002869.mm.2	Mcm10	minichromosome maintenance 10 replication initiation factor	2	-4990723, -4990723	NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689	70024	29	DNA binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding nucleus nucleoplasm nucleolus DNA replication DNA replication initiation cellular response to DNA damage stimulus cell population proliferation enzyme binding replication fork protection complex identical protein binding metal ion binding
TC0300000711.mm.2	Nes	nestin	3	87971092	NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893	18008	988	protein binding cytoplasm intermediate filament intermediate filament intermediate filament multicellular organism development nervous system development intermediate filament binding positive regulation of intermediate filament depolymerization CCR5 chemokine receptor binding CCR5 chemokine receptor binding negative regulation of neuron apoptotic process cell projection morphogenesis
TC1000002212.mm.2	Mcu	mitochondrial calcium uniporter	10	-59446983	NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257	215999	80	calcium channel activity calcium channel activity protein binding mitochondrion mitochondrion mitochondrial inner membrane ion transport calcium ion transport mitochondrial calcium ion transmembrane transport mitochondrial calcium ion transmembrane transport uniporter activity uniporter activity membrane integral component of membrane calcium-mediated signaling integral component of mitochondrial inner membrane integral component of mitochondrial inner membrane positive regulation of insulin secretion calcium channel complex calcium channel complex calcium import into the mitochondrion calcium import into the mitochondrion glucose homeostasis identical protein binding identical protein binding protein complex oligomerization mitochondrial calcium ion homeostasis mitochondrial calcium ion homeostasis positive regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration calcium ion transmembrane transport positive regulation of neutrophil chemotaxis positive regulation of mitochondrial fission actin filament reorganization uniplex complex uniplex complex
MG-1-neg-10339860_st
TC1600001280.mm.2	Sdf2l1	stromal cell-derived factor 2-like 1	16	-17130137	NM_022324, BC053425 NM_022324, BC053425	64136	21	dolichyl-phosphate-mannose-protein mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane membrane endoplasmic reticulum chaperone complex response to endoplasmic reticulum stress protein O-linked mannosylation regulation of apoptotic process chaperone cofactor-dependent protein refolding chaperone binding ATPase binding misfolded protein binding cellular response to misfolded protein ER-associated misfolded protein catabolic process chaperone complex
TC0100002411.mm.2	Wdr12	WD repeat domain 12	1	-60076867, -60076867, -60076867	NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651	57750	23	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding nucleus nucleoplasm nucleolus rRNA processing Notch signaling pathway preribosome, large subunit precursor preribosome, large subunit precursor ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex
TC1300002360.mm.2	Polr3g	polymerase (RNA) III (DNA directed) polypeptide G	13	-81673836	NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818	67486	24	immune system process chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytoplasm cytosol transcription by RNA polymerase III cell population proliferation cell population proliferation cell population proliferation nuclear body positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus	00230 00240 01100 03020 04623
TC1000001204.mm.2	Galnt4	polypeptide N-acetylgalactosaminyltransferase 4	10	99108134	NM_015737, BC057882 NM_015737, BC057882	14426	21	polypeptide N-acetylgalactosaminyltransferase activity Golgi apparatus Golgi apparatus membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine protein O-linked glycosylation via threonine manganese ion binding carbohydrate binding metal ion binding perinuclear region of cytoplasm	00512 01100
TC1000002586.mm.2	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	10	-83600033	NM_145220, BC048906 NM_145220, BC048906	216190	34	ruffle phosphatidylserine binding diet induced thermogenesis protein binding nucleus cytoplasm cytoplasm endosome plasma membrane plasma membrane protein import into nucleus cell cycle transforming growth factor beta receptor signaling pathway cell population proliferation cold acclimation endosome membrane endosome membrane regulation of fibroblast migration membrane signaling small GTPase binding cytoplasmic vesicle vesicle early phagosome ruffle membrane adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway phosphatidylinositol binding cellular response to hepatocyte growth factor stimulus early phagosome membrane glucose homeostasis identical protein binding protein homodimerization activity cell projection macropinosome protein-containing complex binding regulation of innate immune response negative regulation of fatty acid oxidation negative regulation of glucose import negative regulation of glucose import negative regulation of neurogenesis protein homotetramerization positive regulation of phagocytosis, engulfment positive regulation of cold-induced thermogenesis negative regulation of cytokine production involved in inflammatory response negative regulation of cellular response to insulin stimulus positive regulation of macropinocytosis positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis regulation of G1/S transition of mitotic cell cycle negative regulation of neural precursor cell proliferation
TC1100000609.mm.2	Kif3a	kinesin family member 3A	11	53567368	NM_008443, BC052707 NM_008443, BC052707	16568	175	nucleotide binding in utero embryonic development kidney development heart looping cilium movement microtubule motor activity protein binding ATP binding cytoplasm centrosome centriole centriole cytosol cytoskeleton kinesin complex microtubule spindle microtubule cilium axoneme microtubule-based movement smoothened signaling pathway determination of left/right symmetry heart development microtubule binding microtubule binding anterograde axonal transport epidermis development anterior/posterior pattern specification dorsal/ventral pattern formation centriole-centriole cohesion protein transport microtubule cytoskeleton ATPase activity kinesin II complex kinesin II complex kinesin binding protein phosphatase binding dentate gyrus development dorsal/ventral neural tube patterning dorsal/ventral neural tube patterning neural tube development cell projection organization spectrin binding forebrain development small GTPase binding motile cilium photoreceptor connecting cilium microtubule anchoring at centrosome epidermal stem cell homeostasis cell projection neuron projection neuronal cell body motile cilium assembly protein-containing complex binding positive regulation of receptor-mediated endocytosis positive regulation of epithelial cell proliferation inner ear receptor cell stereocilium organization cilium assembly cilium assembly neural precursor cell proliferation positive regulation of intracellular protein transport ribbon synapse intraciliary transport particle B binding protein localization to cell junction axon cytoplasm positive regulation of axo-dendritic protein transport non-motile cilium assembly positive regulation of establishment or maintenance of cell polarity regulating cell shape
TC0600001440.mm.2	Pianp	PILR alpha associated neural protein	6	124998609, 124996719, 124998436	NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170	319352	18	molecular_function biological_process membrane integral component of membrane basolateral plasma membrane regulation of immune response
TC1500001791.mm.2	Arhgap39	Rho GTPase activating protein 39	15	-76723984	NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637	223666	31	GTPase activator activity nucleus cytoplasm cytoskeleton signal transduction postsynapse glutamatergic synapse postsynapse organization
TC1400000179.mm.2	Adk	adenosine kinase	14	21076151, 21052573	NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659	11534	58	nucleotide binding adenosine kinase activity adenosine kinase activity adenosine kinase activity ATP binding nucleus nucleus nucleus nucleoplasm cytoplasm cytosol cytosol cytosol plasma membrane purine ribonucleoside salvage dATP biosynthetic process positive regulation of cardiac muscle hypertrophy kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor positive regulation of T cell proliferation type B pancreatic cell proliferation adenosine metabolic process metal ion binding	00230 01100
TC1200001262.mm.2	Adssl1	adenylosuccinate synthetase like 1	12	112620046	NM_007421, BC039943 NM_007421, BC039943	11565	28	nucleotide binding GTPase activity adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity protein binding GTP binding cytoplasm cytoplasm cytoplasm purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process aspartate metabolic process purine ribonucleoside monophosphate biosynthetic process membrane ligase activity identical protein binding 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding actin filament binding	00230 00250 01100
TC0100003709.mm.2	Degs1	delta(4)-desaturase, sphingolipid 1	1	-182275963, -182275963	NM_007853, BC003751 NM_007853, BC003751	13244	39	mitochondrion endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane oxidoreductase activity sphingolipid biosynthetic process sphingolipid delta-4 desaturase activity sphingolipid delta-4 desaturase activity sphingolipid delta-4 desaturase activity positive regulation of apoptotic process myelin maintenance ceramide biosynthetic process ceramide biosynthetic process retinol isomerase activity retinol isomerase activity	00600 01100
TC1100000028.mm.2	Pes1	pescadillo ribosomal biogenesis factor 1	11	3963974	NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142	64934	35	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed chromosome RNA binding protein binding nucleus nucleoplasm chromosome nucleolus nucleolus cytosol rRNA processing rRNA processing rRNA processing nucleolus organization cell population proliferation preribosome, large subunit precursor protein localization to organelle ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex PeBoW complex
TC0X00003209.mm.2	Kctd12b	potassium channel tetramerisation domain containing 12b	X	-153685153	NM_175429, BC064459 NM_175429, BC064459	207474	12	molecular_function regulation of G protein-coupled receptor signaling pathway receptor complex
TC0600003072.mm.2	Gdf3	growth differentiation factor 3	6	-122605402	NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565	14562	46	skeletal system development eye development in utero embryonic development in utero embryonic development response to dietary excess cytokine activity protein binding extracellular region extracellular space cytoplasm signal transduction multicellular organism development endoderm development endoderm development mesoderm development mesoderm development growth factor activity regulation of cell fate commitment positive regulation of pathway-restricted SMAD protein phosphorylation protein kinase binding BMP signaling pathway negative regulation of BMP signaling pathway notochord development somite rostral/caudal axis specification positive regulation of fat cell differentiation negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation formation of anatomical boundary SMAD protein signal transduction primitive streak formation
TC0X00003371.mm.2	Msl3	MSL complex subunit 3	X	-168651266, -168651266	NM_010832, BC010226 NM_010832, BC010226	17692	22	histone acetyltransferase complex DNA binding nucleus chromatin organization chromatin silencing regulation of transcription, DNA-templated histone acetylation histone deacetylation methylated histone binding NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation histone H4-K16 acetylation histone H4-K16 acetylation histone acetyltransferase activity (H4-K16 specific) MSL complex MSL complex
TC0500003395.mm.2	Hip1	huntingtin interacting protein 1	5	-135406518, -135406495	NM_146001, BC017516 NM_146001, BC017516	215114	55	actin binding protein binding phospholipid binding nucleus cytoplasm Golgi apparatus endocytosis endocytosis apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process actin filament organization membrane clathrin-coated vesicle clathrin-coated vesicle cell differentiation clathrin binding extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle clathrin light chain binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity regulation of apoptotic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding postsynaptic membrane positive regulation of epidermal growth factor receptor signaling pathway protein heterodimerization activity positive regulation of receptor-mediated endocytosis positive regulation of receptor-mediated endocytosis clathrin coat assembly clathrin coat assembly protein stabilization actin filament binding actin filament binding clathrin-dependent endocytosis phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding apoptotic signaling pathway presynapse presynapse postsynapse extrinsic component of presynaptic membrane extrinsic component of postsynaptic membrane extrinsic component of postsynaptic membrane glutamatergic synapse positive regulation of platelet-derived growth factor receptor-beta signaling pathway	05016
TC1200002497.mm.2	D430020J02Rik	RIKEN cDNA D430020J02 gene	12	-116401946	NR_028421	319545	10	molecular_function cellular_component biological_process
TC0200002729.mm.2					NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480			negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II
TC0100001844.mm.2	Pacc1	proton activated chloride channel 1	1	191325901	NM_025864, BC027151 NM_025864, BC027151	66950	15	chloride channel activity plasma membrane integral component of plasma membrane ion transport chloride transport chloride transport membrane integral component of membrane chloride channel complex pH-gated chloride channel activity pH-gated chloride channel activity
TC1200002413.mm.2	Bag5	BCL2-associated athanogene 5	12	-111709489, -111709490	NM_027404, BC037642 NM_027404, BC037642	70369	20	adenyl-nucleotide exchange factor activity protein binding nucleus nucleus cytoplasm mitochondrion cytosol cytosol Golgi organization negative regulation of neuron projection development membrane inclusion body inclusion body protein kinase binding heat shock protein binding negative regulation of protein ubiquitination negative regulation of protein ubiquitination negative regulation of protein ubiquitination ubiquitin protein ligase binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process perinuclear region of cytoplasm perinuclear region of cytoplasm protein stabilization protein stabilization chaperone binding chaperone binding chaperone binding negative regulation of ubiquitin-protein transferase activity negative regulation of ubiquitin-protein transferase activity negative regulation of protein refolding negative regulation of protein refolding neuron death neuron death regulation of inclusion body assembly regulation of inclusion body assembly regulation of inclusion body assembly negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
TC1700000070.mm.2	Rps6ka2	ribosomal protein S6 kinase, polypeptide 2	17	7170114	NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946	20112	56	nucleotide binding magnesium ion binding oocyte maturation brain renin-angiotensin system protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity ribosomal protein S6 kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spindle protein phosphorylation heart development negative regulation of cell population proliferation positive regulation of gene expression cardiac muscle cell apoptotic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation intracellular signal transduction positive regulation of apoptotic process negative regulation of cell cycle negative regulation of meiotic nuclear division heart contraction regulation of protein processing regulation of protein processing cellular response to carbohydrate stimulus meiotic spindle	04010 04114 04150 04720 04722 04914
TC1100004267.mm.2	Trim16	tripartite motif-containing 16	11	62820252	NM_053169, BC052821 NM_053169, BC052821	94092	20	DNA binding cytoplasm cytoplasm cytosol plasma membrane zinc ion binding PML body transferase activity interleukin-1 binding NACHT domain binding positive regulation of interleukin-1 beta production histone H3 acetylation histone H4 acetylation positive regulation of keratinocyte differentiation positive regulation of transcription, DNA-templated metal ion binding positive regulation of retinoic acid receptor signaling pathway response to growth hormone
TC1000001686.mm.2	Fbxo5	F-box protein 5	10	-5799157	NM_025995, BC053434 NM_025995, BC053434	67141	29	oocyte maturation oocyte maturation protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm spindle cytoskeleton regulation of DNA replication cell cycle spindle assembly involved in female meiosis I regulation of mitotic nuclear division regulation of mitotic cell cycle positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex binding vesicle organization protein kinase binding negative regulation of DNA endoreduplication regulation of meiotic nuclear division positive regulation of osteoblast differentiation negative regulation of meiotic nuclear division negative regulation of meiotic nuclear division negative regulation of mitotic metaphase/anaphase transition microtubule polymerization metal ion binding spindle assembly cell division negative regulation of ubiquitin-protein transferase activity positive regulation of meiosis I positive regulation of biomineral tissue development meiotic spindle negative regulation of ubiquitin protein ligase activity positive regulation of mesenchymal stem cell migration ubiquitin ligase inhibitor activity negative regulation of cellular senescence negative regulation of response to DNA damage stimulus	04114
TC1000001593.mm.2	Timeless	timeless circadian clock 1	10	128232062, 128238065	NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770	21853	45	DNA replication checkpoint negative regulation of transcription by RNA polymerase II chromatin branching involved in ureteric bud morphogenesis kidney development morphogenesis of an epithelium DNA binding protein binding nucleus nucleus nucleoplasm chromosome DNA repair cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle multicellular organism development circadian rhythm embryo development lung development replication fork protection complex site of double-strand break regulation of circadian rhythm regulation of circadian rhythm positive regulation of circadian rhythm identical protein binding replication fork arrest cell cycle phase transition negative regulation of transcription, DNA-templated replication fork protection rhythmic process branching morphogenesis of an epithelial tube cell division cellular response to hydroxyurea cellular response to cisplatin cellular response to bleomycin positive regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair
TC0100002964.mm.2	Dbi	diazepam binding inhibitor	1	-120113279, -120113279	NM_001037999, NM_007830, BC028874 NM_001037999, NM_007830, BC028874 NM_001037999, NM_007830, BC028874	13167	65	fatty-acyl-CoA binding behavioral fear response hair follicle development extracellular space nucleus cytoplasm mitochondrion endoplasmic reticulum Golgi apparatus plasma membrane triglyceride metabolic process learning or memory synaptic vesicle lipid binding glial cell proliferation lateral ventricle development benzodiazepine receptor binding negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic protein-lipid complex long-chain fatty acyl-CoA binding phosphatidylcholine acyl-chain remodeling identical protein binding contractile fiber skin development positive regulation of lipid biosynthetic process positive regulation of release of sequestered calcium ion into cytosol long-term synaptic potentiation perinuclear endoplasmic reticulum negative regulation of protein lipidation positive regulation of CoA-transferase activity positive regulation of phospholipid transport	03320
TC1500000524.mm.2	Ptp4a3	protein tyrosine phosphatase 4a3	15	73723144, 73748025, 73724929, 73724796	NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043	19245	42	phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleus cytoplasm cytoplasm endosome plasma membrane regulation of transcription, DNA-templated protein dephosphorylation Notch signaling pathway membrane dephosphorylation hydrolase activity phosphatase activity positive regulation of vascular permeability endothelial cell migration endothelial cell migration endothelial cell migration regulation of vascular endothelial growth factor signaling pathway positive regulation of NIK/NF-kappaB signaling positive regulation of establishment of protein localization cellular response to leukemia inhibitory factor
TC0700001897.mm.2	Wdr11	WD repeat domain 11	7	129591862	NM_172255, BC037177 NM_172255, BC037177	207425	23	protein binding nucleus nucleus cytoplasm cytoplasm Golgi apparatus trans-Golgi network cytosol cytoskeleton cilium axoneme intracellular protein transport heart development regulation of smoothened signaling pathway microtubule cytoskeleton cytoplasmic vesicle multicellular organism growth ciliary basal body ciliary basal body cell projection cilium assembly head development vesicle tethering to Golgi
TC1300002609.mm.2	Rnf180	ring finger protein 180	13	-105147493, -105130569	NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700	71816	19	protein polyubiquitination protein binding nucleus endoplasmic reticulum membrane integral component of membrane transferase activity adult behavior intrinsic component of endoplasmic reticulum membrane intrinsic component of endoplasmic reticulum membrane positive regulation of protein ubiquitination ubiquitin conjugating enzyme binding ubiquitin conjugating enzyme binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process norepinephrine metabolic process norepinephrine metabolic process serotonin metabolic process serotonin metabolic process metal ion binding regulation of catalytic activity ubiquitin protein ligase activity ubiquitin protein ligase activity organic cyclic compound metabolic process
TC1600001471.mm.2	Xxylt1	xyloside xylosyltransferase 1	16	-30955502	NM_198626, BC031419 NM_198626, BC031419	268880	16	magnesium ion binding protein binding endoplasmic reticulum membrane integral component of membrane O-glycan processing O-glycan processing transferase activity transferase activity, transferring glycosyl groups manganese ion binding manganese ion binding integral component of endoplasmic reticulum membrane UDP-xylosyltransferase activity UDP-xylosyltransferase activity metal ion binding
TC0400000743.mm.2	Tlr4	toll-like receptor 4	4	66827550	NM_021297, BC029856 NM_021297, BC029856	21898	2990	activation of MAPK activity lipopolysaccharide binding lipopolysaccharide binding microglial cell activation lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity phagocytic cup activation of innate immune response toll-like receptor signaling pathway toll-like receptor signaling pathway B cell proliferation involved in immune response immune system process nitric oxide production involved in inflammatory response regulation of dendritic cell cytokine production MyD88-dependent toll-like receptor signaling pathway innate immune response-activating signal transduction signaling receptor binding protein binding cytoplasm endosome Golgi apparatus plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane leukotriene metabolic process phagocytosis inflammatory response response to oxidative stress signal transduction activation of NF-kappaB-inducing kinase activity I-kappaB phosphorylation I-kappaB phosphorylation response to bacterium external side of plasma membrane cell surface positive regulation of platelet activation positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression positive regulation of keratinocyte proliferation astrocyte development membrane integral component of membrane hydrolase activity positive regulation of B cell proliferation intrinsic component of plasma membrane lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide interferon-gamma production interleukin-1 beta production regulation of tumor necrosis factor production negative regulation of interferon-gamma production negative regulation of interleukin-17 production negative regulation of interleukin-23 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of interferon-gamma production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 4 signaling pathway TRIF-dependent toll-like receptor signaling pathway signaling receptor activity macrophage activation macrophage activation macrophage activation defense response to bacterium identical protein binding cell projection positive regulation of macrophage activation positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling receptor complex receptor complex positive regulation of DNA binding phosphatidylinositol 3-kinase binding innate immune response membrane raft positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol mast cell activation positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of JNK cascade lipopolysaccharide receptor complex protein heterodimerization activity perinuclear region of cytoplasm NAD(P)+ nucleosidase activity positive regulation of lymphocyte proliferation regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium defense response to Gram-negative bacterium detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process regulation of sensory perception of pain intestinal epithelial structure maintenance positive regulation of macrophage cytokine production NAD+ nucleotidase, cyclic ADP-ribose generating negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway response to fatty acid cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to interferon-gamma negative regulation of cold-induced thermogenesis cellular response to oxidised low-density lipoprotein particle stimulus positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly positive regulation of NIK/NF-kappaB signaling positive regulation of oxidative stress-induced neuron death positive regulation of reactive oxygen species biosynthetic process positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of matrix metallopeptidase secretion cellular response to amyloid-beta positive regulation of chemokine (C-X-C motif) ligand 2 production	04145 04620 05140 05142 05144 05145 05146 05323
TC0100003786.mm.2	Smyd2	SET and MYND domain containing 2	1	-189880491	NM_026796, BC023119 NM_026796, BC023119	226830	30	negative regulation of transcription by RNA polymerase II RNA polymerase II complex binding p53 binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol chromatin organization methyltransferase activity negative regulation of cell population proliferation protein-lysine N-methyltransferase activity histone methylation transferase activity histone-lysine N-methyltransferase activity peptidyl-lysine monomethylation peptidyl-lysine dimethylation methylation histone lysine methylation regulation of DNA damage response, signal transduction by p53 class mediator metal ion binding histone methyltransferase activity (H3-K36 specific)
TC1800000583.mm.2	Slc12a2	solute carrier family 12, member 2	18	57878677	NM_009194	20496	193	transporter activity protein binding cytosol plasma membrane ion transport potassium ion transport sodium ion transport chloride transport cellular sodium ion homeostasis cell volume homeostasis cell volume homeostasis hyperosmotic response gamma-aminobutyric acid signaling pathway sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity ammonium transmembrane transporter activity ammonium transmembrane transporter activity basal plasma membrane T cell chemotaxis T cell chemotaxis potassium ion transmembrane transporter activity symporter activity cation:chloride symporter activity potassium:chloride symporter activity ammonium transport ammonium transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane lateral plasma membrane protein kinase binding cellular potassium ion homeostasis transepithelial chloride transport cellular chloride ion homeostasis cytoplasmic vesicle membrane multicellular organism growth maintenance of blood-brain barrier sodium ion transmembrane transport cellular response to potassium ion cell projection neuron projection neuronal cell body neuronal cell body cell body positive regulation of cell volume metal ion transmembrane transporter activity detection of mechanical stimulus involved in sensory perception of sound chaperone binding Hsp90 protein binding chloride ion homeostasis potassium ion homeostasis sodium ion homeostasis transmembrane transport branching involved in mammary gland duct morphogenesis mammary duct terminal end bud growth negative regulation of vascular wound healing transepithelial ammonium transport cell periphery cell periphery inorganic anion import across plasma membrane inorganic cation import across plasma membrane sodium ion import across plasma membrane regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission chloride transmembrane transport chloride transmembrane transport positive regulation of aspartate secretion regulation of matrix metallopeptidase secretion potassium ion import across plasma membrane potassium ion import across plasma membrane cellular response to chemokine cellular response to chemokine	04970 04972
MG-1-pos-10343494_st
TC0X00000181.mm.2	Maoa	monoamine oxidase A	X	16619697	NM_173740, BC029100 NM_173740, BC029100	17161	136	protein binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane cytosol catecholamine metabolic process primary amine oxidase activity primary amine oxidase activity positive regulation of signal transduction membrane integral component of membrane oxidoreductase activity neurotransmitter catabolic process dopamine catabolic process serotonin metabolic process phenylethylamine metabolic process flavin adenine dinucleotide binding serotonin binding	00260 00330 00340 00350 00360 00380 00982 01100
TC1100001095.mm.2	Tlcd3a	TLC domain containing 3A	11	76202091, 76179670, 76179670	NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520	116972	15	molecular_function endoplasmic reticulum plasma membrane membrane integral component of membrane lipid homeostasis
TC1400001032.mm.2	Lpar6	lysophosphatidic acid receptor 6	14	73237890	NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942	67168	28	blastocyst hatching G protein-coupled receptor activity plasma membrane integral component of plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway lysophosphatidic acid receptor activity	04080
TC0900000050.mm.2	Mmp8	matrix metallopeptidase 8	9	7558428	NM_008611, BC042742 NM_008611, BC042742	17394	93	endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding positive regulation of gene expression negative regulation of gene expression hydrolase activity extracellular matrix organization collagen catabolic process extracellular matrix negative regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of DNA binding positive regulation of MAPK cascade positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of JNK cascade metal ion binding positive regulation of neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of NIK/NF-kappaB signaling positive regulation of reactive oxygen species biosynthetic process positive regulation of microglial cell activation
TC0100001351.mm.2	Ivns1abp	influenza virus NS1A binding protein	1	151344485, 151344497, 151344497	NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092	117198	29	protein binding nucleus cytoplasm cytosol cytoskeleton RNA splicing response to virus negative regulation of protein ubiquitination negative regulation of intrinsic apoptotic signaling pathway
TC0200000319.mm.2	Etl4	enhancer trap locus 4	2	20519512, 20289912, 20510046	NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051	208618	46	protein binding cytoplasm cytoplasm multicellular organism development enzyme regulator activity embryonic skeletal system development
TC0800002339.mm.2	Psd3	pleckstrin and Sec7 domain containing 3	8	-67689081, -67689081, -67689081	NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698	234353	22	guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse	04144
TC1900000399.mm.2	Dock8	dedicator of cytokinesis 8	19	24999528	NM_028785, BC141358 NM_028785, BC141358	76088	43	immunological synapse formation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm plasma membrane small GTPase mediated signal transduction membrane cell leading edge leading edge membrane dendritic cell migration dendritic cell migration cell projection positive regulation of GTPase activity memory T cell proliferation negative regulation of T cell apoptotic process positive regulation of establishment of T cell polarity positive regulation of establishment of T cell polarity cellular response to chemokine positive regulation of T cell migration positive regulation of T cell migration
TC0800003176.mm.2	2810004N23Rik	RIKEN cDNA 2810004N23 gene	8	-124839354	NM_025615, BC023675 NM_025615, BC023675	66523	19	chromosome biological_process
TC1000001020.mm.2	Tcp11l2	t-complex 11 (mouse) like 2	10	84576946	NM_146008, BC029663 NM_146008, BC029663	216198	14	molecular_function cellular_component signal transduction
TC1300000967.mm.2	Mblac2	metallo-beta-lactamase domain containing 2	13	81711416	NM_028372, BC160254 NM_028372, BC160254	72852	12	biological_process hydrolase activity metal ion binding
TC1500001596.mm.2	Washc5	WASH complex subunit 5	15	-59331996	NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035	223593	31	oocyte maturation nucleoplasm cytoplasm endosome endosome endosome early endosome endoplasmic reticulum exocytosis phagocytosis endosome organization lysosome organization lysosome organization positive regulation of neuron projection development protein transport endosomal transport actin filament polymerization cellular protein-containing complex localization polar body extrusion after meiotic divisions cholesterol homeostasis identical protein binding neuron projection neuronal cell body protein-containing complex subunit organization protein-containing complex subunit organization regulation of actin nucleation regulation of actin nucleation WASH complex WASH complex WASH complex spindle assembly involved in meiosis regulation of vesicle size endosome fission endosome fission
TC0400000519.mm.2	Tgfbr1	transforming growth factor, beta receptor I	4	47353221, 47386215	NM_009370, BC063260 NM_009370, BC063260	21812	328	nucleotide binding activation of MAPKK activity skeletal system development angiogenesis in utero embryonic development kidney development blastocyst development epithelial to mesenchymal transition negative regulation of endothelial cell proliferation lens development in camera-type eye ventricular trabecula myocardium morphogenesis ventricular compact myocardium morphogenesis protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta-activated receptor activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type I transforming growth factor beta receptor activity, type I signaling receptor binding type II transforming growth factor beta receptor binding protein binding ATP binding nucleus endosome endosome plasma membrane plasma membrane caveola bicellular tight junction regulation of transcription, DNA-templated protein phosphorylation protein phosphorylation apoptotic process signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway nervous system development heart development heart development positive regulation of cell population proliferation germ cell migration male gonad development embryo development post-embryonic development anterior/posterior pattern specification cell surface regulation of gene expression positive regulation of gene expression positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral component of membrane kinase activity phosphorylation basolateral plasma membrane apical plasma membrane activin receptor activity, type I transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation growth factor binding cell junction cell differentiation collagen fibril organization positive regulation of cell growth positive regulation of cell migration regulation of protein ubiquitination ubiquitin protein ligase binding negative regulation of chondrocyte differentiation activin receptor signaling pathway protein-containing complex regulation of growth positive regulation of apoptotic process negative regulation of apoptotic process receptor complex receptor complex regulation of protein binding endothelial cell migration response to estrogen protein-containing complex binding membrane raft negative regulation of endothelial cell differentiation positive regulation of transcription, DNA-templated SMAD binding SMAD binding SMAD binding protein autophosphorylation metal ion binding activin receptor complex activin binding thymus development neuron fate commitment embryonic cranial skeleton morphogenesis skeletal system morphogenesis artery morphogenesis cell motility transforming growth factor beta binding transforming growth factor beta binding positive regulation of cellular component movement positive regulation of filopodium assembly positive regulation of stress fiber assembly positive regulation of protein kinase B signaling parathyroid gland development roof of mouth development roof of mouth development pharyngeal system development regulation of cardiac muscle cell proliferation pathway-restricted SMAD protein phosphorylation positive regulation of SMAD protein signal transduction ventricular septum morphogenesis angiogenesis involved in coronary vascular morphogenesis coronary artery morphogenesis I-SMAD binding response to cholesterol response to cholesterol cellular response to growth factor stimulus cellular response to transforming growth factor beta stimulus cellular response to transforming growth factor beta stimulus negative regulation of pri-miRNA transcription by RNA polymerase II positive regulation of pri-miRNA transcription by RNA polymerase II positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation positive regulation of tight junction disassembly epicardium morphogenesis positive regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway	04010 04060 04144 04350 04380 04520 05142 05200 05210 05212 05220
TC0100001836.mm.2	Nsl1	NSL1, MIS12 kinetochore complex component	1	191063020	NM_198654, BC029086 NM_198654, BC029086	381318	14	mitotic sister chromatid segregation MIS12/MIND type complex MIS12/MIND type complex chromosome, centromeric region kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cell cycle chromosome segregation nuclear speck cell division
TC1000001074.mm.2	Nup37	nucleoporin 37	10	88146991, 88147070	NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180	69736	19	chromosome, centromeric region kinetochore molecular_function nucleus nuclear pore nucleoplasm chromosome cell cycle chromosome segregation protein transport nuclear pore outer ring nuclear pore outer ring mRNA transport cell division	03013
TC1600001254.mm.2	Mcm4	minichromosome maintenance complex component 4	16	-15623896	NM_008565, BC013094 NM_008565, BC013094	17217	66	nucleotide binding double-strand break repair via break-induced replication DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex mitotic DNA replication initiation	03030 04110
TC1600000530.mm.2	Polq	polymerase (DNA directed), theta	16	37011785	NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900	77782	34	nucleotide binding nucleic acid binding DNA binding chromatin binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity ATP binding nucleus nucleoplasm chromosome cytoplasm Golgi apparatus cytosol DNA replication DNA-dependent DNA replication DNA repair DNA repair base-excision repair double-strand break repair cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes transferase activity nucleotidyltransferase activity single-stranded DNA helicase activity identical protein binding protein homooligomerization 5'-deoxyribose-5-phosphate lyase activity double-strand break repair via alternative nonhomologous end joining double-strand break repair via alternative nonhomologous end joining negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination
TC0900000255.mm.2	Ncapd3	non-SMC condensin II complex, subunit D3	9	27030164, 27060415	NM_178113, BC048190 NM_178113, BC048190	78658	20	condensed chromosome kinetochore condensed chromosome, centromeric region condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm pericentric heterochromatin cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation methylated histone binding histone binding germinal vesicle cell division meiotic chromosome separation
TC0100003531.mm.2	Pcp4l1	Purkinje cell protein 4-like 1	1	-171173263	NM_025557	66425	17	molecular_function cellular_component biological_process
TC0300001076.mm.2	Slc16a1	solute carrier family 16 (monocarboxylic acid transporters), member 1	3	104638663	NM_009196, BC014777 NM_009196, BC014777	20501	88	mitochondrion centrosome plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane lipid metabolic process centrosome cycle monocarboxylic acid transmembrane transporter activity monocarboxylic acid transmembrane transporter activity basal plasma membrane lactate transmembrane transporter activity symporter activity monocarboxylic acid transport monocarboxylic acid transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane cell junction response to food lactate transmembrane transport plasma membrane lactate transport plasma membrane lactate transport glucose homeostasis identical protein binding intracellular membrane-bounded organelle synapse synapse carboxylic acid transmembrane transporter activity regulation of insulin secretion behavioral response to nutrient transmembrane transport cellular response to organic cyclic compound organic cyclic compound binding carboxylic acid transmembrane transport
TC1100002813.mm.2	Gemin5	gem nuclear organelle associated protein 5	11	-58120000, -58120000	NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922	216766	23	RNA 7-methylguanosine cap binding spliceosomal snRNP assembly RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleoplasm cytoplasm cytosol mRNA processing translation regulation of translation RNA splicing nuclear body snRNA binding U1 snRNA binding U4 snRNA binding U4atac snRNA binding SMN complex SMN-Gemin2 complex SMN-Sm protein complex ribosome binding	03013
TC0900002115.mm.2	Sc5d	sterol-C5-desaturase	9	-42254176	NM_172769, BC024132 NM_172769, BC024132	235293	30	C-5 sterol desaturase activity C-5 sterol desaturase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process steroid metabolic process lipid biosynthetic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity cholesterol biosynthetic process via lathosterol cholesterol biosynthetic process via lathosterol intracellular membrane-bounded organelle	00100 01100
TC0900003342.mm.2	Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein	9	-88449363, -88455581	NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363	56403	66	nucleic acid binding RNA binding mRNA binding nucleus spliceosomal complex cytoplasm endoplasmic reticulum mRNA processing poly(A) binding RNA splicing negative regulation of translation intracellular membrane-bounded organelle mRNA 5'-UTR binding CRD-mediated mRNA stabilization CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex CRD-mediated mRNA stability complex catalytic step 2 spliceosome histone pre-mRNA 3'end processing complex cellular response to interferon-gamma GAIT complex ribonucleoprotein complex ribonucleoprotein complex
TC0500002508.mm.2	Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2	5	-66298724, -66298724	NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587	11787	36	amyloid-beta binding neuron migration protein binding nucleus nucleus cytoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated cell cycle arrest axon guidance transcription factor binding transcription factor binding actin filament-based movement extracellular matrix organization negative regulation of cell growth histone acetyltransferase binding positive regulation of apoptotic process negative regulation of apoptotic process protein stabilization
MG-1-neg-10339217_st
TC0900003248.mm.2	Cx3cr1	chemokine (C-X3-C motif) receptor 1	9	-120048682	NM_009987, BC012653 NM_009987, BC012653	13051	1010	microglial cell activation positive regulation of neuroblast proliferation microglial cell activation involved in immune response negative regulation of chronic inflammatory response to non-antigenic stimulus response to ischemia cytokine receptor activity G protein-coupled receptor activity chemokine receptor activity plasma membrane chemotaxis immune response cell adhesion signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration memory external side of plasma membrane cell surface cell surface membrane integral component of membrane C-C chemokine receptor activity C-X3-C chemokine receptor activity negative regulation of angiogenesis cytokine-mediated signaling pathway calcium-mediated signaling C-C chemokine binding C-X3-C chemokine binding C-X3-C chemokine binding central nervous system maturation cerebral cortex cell migration negative regulation of cell migration regulation of tumor necrosis factor production negative regulation of interleukin-1 beta production neuronal cell body membrane social behavior autocrine signaling neuron projection innate immune response regulation of nitric oxide biosynthetic process positive regulation of angiogenesis macrophage chemotaxis perinuclear region of cytoplasm positive regulation of neurogenesis modulation of chemical synaptic transmission leukocyte tethering or rolling positive regulation of NF-kappaB transcription factor activity positive regulation of protein kinase B signaling synapse maturation cell chemotaxis cell chemotaxis chemokine-mediated signaling pathway cellular response to lipopolysaccharide dendritic tree negative regulation of hippocampal neuron apoptotic process multiple spine synapse organization, single dendrite negative regulation of long-term synaptic potentiation positive regulation of I-kappaB phosphorylation positive regulation of microglial cell migration negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	04060 04062
TC1300001349.mm.2	Tmem267	transmembrane protein 267	13	119488472, 119488085	NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784	633640	12	molecular_function cellular_component biological_process membrane integral component of membrane
TC1200000719.mm.2	Rad51b	RAD51 paralog B	12	79297281, 79297350	NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184	19363	22	nucleotide binding four-way junction DNA binding four-way junction DNA binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination in utero embryonic development in utero embryonic development blastocyst growth DNA binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding ATP binding nucleus replication fork replication fork DNA repair DNA recombination cellular response to DNA damage stimulus DNA-dependent ATPase activity DNA-dependent ATPase activity positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle Rad51B-Rad51C-Rad51D-XRCC2 complex Rad51B-Rad51C-Rad51D-XRCC2 complex somite development	03440
TC1300001445.mm.2	Mtr	5-methyltetrahydrofolate-homocysteine methyltransferase	13	-12186539	NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685	238505	25	folic acid binding cytoplasm cytosol cytosol protein methylation methionine metabolic process methyltransferase activity zinc ion binding cellular amino acid biosynthetic process methionine synthase activity methionine synthase activity methionine synthase activity methionine biosynthetic process methionine biosynthetic process cobalamin metabolic process amino acid binding transferase activity axon regeneration cobalamin binding methylation pteridine-containing compound metabolic process cellular metabolic process tetrahydrofolate metabolic process metal ion binding response to axon injury homocysteine metabolic process cellular response to nitric oxide	00270 00450 00670 01100
TC1000003078.mm.2	Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	10	-125219269, -125219269	NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960	20503	44	nucleoplasm cytoplasm plasma membrane integral component of plasma membrane integral component of plasma membrane monocarboxylic acid transmembrane transporter activity lactate transmembrane transporter activity symporter activity monocarboxylic acid transport membrane integral component of membrane lactate transmembrane transport plasma membrane lactate transport pyruvate transmembrane transporter activity transmembrane transport Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse parallel fiber to Purkinje cell synapse glutamatergic synapse integral component of postsynaptic density membrane pyruvate transmembrane transport
TC0200005378.mm.2	Gm14326	predicted gene 14326	2	-177944590, -177935992	NM_001190302, NM_001282028 NM_001190302, NM_001282028	665211	9	molecular_function cellular_component biological_process
TC0800001263.mm.2	Nip7	NIP7, nucleolar pre-rRNA processing protein	8	107056876	NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972	66164	19	RNA binding nucleus nucleoplasm nucleolus nucleolus cytosol preribosome, large subunit precursor ribosome biogenesis ribosome assembly ribosomal large subunit biogenesis
TC1700002794.mm.2					NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983			molecular_function protein binding cellular_component cytosol cytoplasmic dynein complex microtubule-based movement biological_process extrinsic component of membrane sperm flagellum
TC1700002497.mm.2	Ndc80	NDC80 kinetochore complex component	17	-71496099	NM_023294, BC020131 NM_023294, BC020131	67052	29	mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome outer kinetochore protein binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cell cycle mitotic spindle organization spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I chromosome segregation G2/MI transition of meiotic cell cycle attachment of spindle microtubules to kinetochore cyclin binding Ndc80 complex Ndc80 complex regulation of protein stability identical protein binding centrosome duplication cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore attachment of mitotic spindle microtubules to kinetochore kinetochore organization kinetochore organization positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of protein localization to kinetochore
TC0100002739.mm.2	Ncl	nucleolin	1	-86344718	NM_010880, BC005460 NM_010880, BC005460	17975	127	angiogenesis fibrillar center dense fibrillar component nucleic acid binding DNA binding single-stranded DNA binding RNA binding RNA binding signaling receptor binding calcium ion binding protein binding nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex chromosome nucleolus nucleolus cytoplasm cell cortex endocytosis protein C-terminus binding cell surface negative regulation of translation positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production selenocysteine insertion sequence binding cytoplasmic ribonucleoprotein granule rRNA primary transcript binding telomeric DNA binding histone binding identical protein binding negative regulation of apoptotic process laminin binding sequence-specific DNA binding DNA topoisomerase binding positive regulation of transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome mRNA 5'-UTR binding cellular response to lipopolysaccharide cellular response to epidermal growth factor stimulus positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ErbB-4 class receptor binding cellular response to leukemia inhibitory factor ribonucleoprotein complex regulation of rRNA processing
TC1400000174.mm.2	Zswim8	zinc finger SWIM-type containing 8	14	20707551	NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103	268721	20	molecular_function cytosol zinc ion binding Cul2-RING ubiquitin ligase complex metal ion binding regulation of axon guidance
TC0900001908.mm.2	Anln	anillin, actin binding protein	9	-22331213	NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164	68743	47	mitotic cytokinesis mitotic cytokinesis actomyosin contractile ring assembly hematopoietic progenitor cell differentiation actin binding nucleus nucleoplasm cytoplasm actomyosin contractile ring actomyosin contractile ring cytoskeleton cell cycle actin cytoskeleton midbody septin ring organization bleb cell projection cell division glomerular visceral epithelial cell migration cell cortex region positive regulation of bleb assembly
TC1300000383.mm.2	Nqo2	N-ribosyldihydronicotinamide quinone reductase 2	13	33967152, 33964658	NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629	18105	32	dihydronicotinamide riboside quinone reductase activity NAD(P)H dehydrogenase (quinone) activity nucleoplasm cytoplasm cytosol cytosol zinc ion binding electron transfer activity oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors chloride ion binding protein homodimerization activity positive regulation of neuron apoptotic process metal ion binding positive regulation of ERK1 and ERK2 cascade FAD binding melatonin binding positive regulation of vascular associated smooth muscle cell proliferation resveratrol binding positive regulation of reactive oxygen species metabolic process
TC1100003693.mm.2	Top2a	topoisomerase (DNA) II alpha	11	-98992946	NM_011623	21973	101	nucleotide binding nuclear chromosome magnesium ion binding resolution of meiotic recombination intermediates chromosome, centromeric region condensed chromosome condensed chromosome sister chromatid segregation hematopoietic progenitor cell differentiation DNA binding chromatin binding DNA topoisomerase activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm centriole DNA metabolic process DNA topological change DNA topological change DNA ligation cellular response to DNA damage stimulus chromosome segregation chromosome segregation chromosome segregation female meiotic nuclear division protein C-terminus binding DNA-dependent ATPase activity DNA binding, bending DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex isomerase activity enzyme binding chromosome condensation apoptotic chromosome condensation apoptotic chromosome condensation protein-containing complex embryonic cleavage regulation of circadian rhythm protein homodimerization activity histone deacetylase binding positive regulation of apoptotic process ubiquitin binding sequence-specific DNA binding positive regulation of single stranded viral RNA replication via double stranded DNA intermediate positive regulation of transcription by RNA polymerase II metal ion binding protein heterodimerization activity rhythmic process female meiosis chromosome separation negative regulation of DNA duplex unwinding ribonucleoprotein complex
TC1600001380.mm.2	Dgkg	diacylglycerol kinase, gamma	16	-22466568	NM_138650, BC015278 NM_138650, BC015278	110197	36	nucleotide binding NAD+ kinase activity diacylglycerol kinase activity diacylglycerol kinase activity diacylglycerol kinase activity calcium ion binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway lipid binding membrane kinase activity phosphorylation transferase activity intracellular signal transduction diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process glycerolipid metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding regulation of dendrite development negative regulation of protein kinase C signaling	00561 00564 01100 04070
TC0X00002826.mm.2	Taf9b	TATA-box binding protein associated factor 9B	X	-106206873, -106206873	NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223	407786	20	negative regulation of transcription by RNA polymerase II nucleus transcription factor TFIID complex transcription factor TFIID complex DNA-templated transcription, initiation transcription by RNA polymerase II RNA polymerase II general transcription initiation factor activity positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptotic process protein heterodimerization activity protein stabilization	03022
TC0600000989.mm.2	C87436	expressed sequence C87436	6	86438673, 86438397, 86438645, 86438375	NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913	232196	18	molecular_function nucleus nucleoplasm biological_process
TC0700002311.mm.2	Zik1	zinc finger protein interacting with K protein 1	7	-10487223	NM_009577, BC050942, BC067196 NM_009577, BC050942, BC067196 NM_009577, BC050942, BC067196	22775	21	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleic acid binding DNA binding intracellular anatomical structure nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II metal ion binding
TC1300000928.mm.2	Mctp1	multiple C2 domains, transmembrane 1	13	76384138, 76579596	NM_030174	78771	13	calcium ion binding calcium ion binding endosome endoplasmic reticulum membrane integral component of membrane integral component of membrane cell junction negative regulation of cell migration synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle synapse negative regulation of endocytosis metal ion binding regulation of neurotransmitter secretion recycling endosome negative regulation of response to oxidative stress
TC0500000928.mm.2	Anxa3	annexin A3	5	96793384	NM_013470, BC090634, BC141167 NM_013470, BC090634, BC141167 NM_013470, BC090634, BC141167	11745	28	phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding cytoplasm cytoplasm plasma membrane phagocytosis positive regulation of endothelial cell migration membrane phospholipase A2 inhibitor activity axon dendrite phagocytic vesicle membrane specific granule defense response to bacterium neuronal cell body neutrophil degranulation positive regulation of angiogenesis calcium-dependent protein binding positive regulation of DNA metabolic process positive regulation of DNA-binding transcription factor activity collagen-containing extracellular matrix
TC0400002460.mm.2	Ubap2	ubiquitin-associated protein 2	4	-41194314	NM_026872, BC007179 NM_026872, BC007179	68926	25	nucleus cytoplasm
TC0500001428.mm.2	Kntc1	kinetochore associated 1	5	123749725	NM_001042421	208628	20	chromosome, centromeric region kinetochore spindle pole molecular_function nucleus chromosome cytoplasm kinetochore microtubule cytosol cytoskeleton plasma membrane cell cycle mitotic spindle assembly checkpoint actin cytoskeleton cell division RZZ complex
TC0500000324.mm.2	Gpn1	GPN-loop GTPase 1	5	31494740	NM_133756, BC020174, BC096466 NM_133756, BC020174, BC096466 NM_133756, BC020174, BC096466	74254	17	nucleotide binding GTPase activity GTP binding nucleus nucleoplasm cytoplasm mitochondrion cytosol hydrolase activity
TC0200001947.mm.2	Polr1b	polymerase (RNA) I polypeptide B	2	129100995	NM_009086, BC060656 NM_009086, BC060656	20017	35	DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm chromosome nucleolus nucleolus RNA polymerase I complex RNA polymerase I complex RNA polymerase I complex cytosol transcription, DNA-templated embryo implantation rRNA transcription rRNA transcription embryo development transferase activity nucleotidyltransferase activity nucleologenesis ribonucleoside binding metal ion binding	00230 00240 01100 03020
TC0400001596.mm.2	Rpa2	replication protein A2	4	132768359	NM_011284, BC004578 NM_011284, BC004578	19891	46	telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region chromosome, telomeric region chromatin DNA binding damaged DNA binding single-stranded DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination cellular response to DNA damage stimulus regulation of double-strand break repair via homologous recombination nuclear body PML body enzyme binding protein phosphatase binding mitotic G1 DNA damage checkpoint ubiquitin protein ligase binding protein localization to chromosome site of double-strand break site of double-strand break protein N-terminus binding G-rich strand telomeric DNA binding regulation of DNA damage checkpoint	03030 03420 03430 03440
TC1100003124.mm.2	Nlrp1a	NLR family, pyrin domain containing 1A	11	-71091196	NM_001004142	195046	38	nucleotide binding protein binding ATP binding cytoplasm activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response response to muramyl dipeptide positive regulation of interleukin-1 beta production protein-containing complex defense response to bacterium regulation of apoptotic process neuronal cell body innate immune response inflammasome complex scaffold protein binding programmed necrotic cell death	04621
TC1100003945.mm.2	Nol11	nucleolar protein 11	11	-107166652	NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874	68979	19	nucleus nucleolus nucleolus rRNA processing maturation of SSU-rRNA maturation of SSU-rRNA t-UTP complex ribosome biogenesis positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
TC0200003182.mm.2	Qsox2	quiescin Q6 sulfhydryl oxidase 2	2	-26209123	NM_153559, BC030934 NM_153559, BC030934	227638	17	protein disulfide isomerase activity extracellular space nucleoplasm Golgi apparatus protein folding membrane integral component of membrane oxidoreductase activity flavin-linked sulfhydryl oxidase activity thiol oxidase activity integral component of Golgi membrane cell redox homeostasis
TC0800002960.mm.2	Adat1	adenosine deaminase, tRNA-specific 1	8	-111970864, -111966897	NM_013925, BC019976 NM_013925, BC019976	30947	14	RNA binding adenosine deaminase activity cellular_component RNA processing tRNA processing tRNA-specific adenosine deaminase activity tRNA-specific adenosine deaminase activity hydrolase activity metal ion binding
TC0700002102.mm.2	Dhcr7	7-dehydrocholesterol reductase	7	143830213, 143823166, 143823398	NM_007856, BC006854 NM_007856, BC006854	13360	56	blood vessel development nuclear outer membrane endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process post-embryonic development sterol delta7 reductase activity membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process brassinosteroid biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor cell differentiation integral component of endoplasmic reticulum membrane lung development multicellular organism growth regulation of cell population proliferation intracellular membrane-bounded organelle regulation of cholesterol biosynthetic process 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity	00100 01100
TC1000000047.mm.2	Nup43	nucleoporin 43	10	7667503	NM_145706, BC011060 NM_145706, BC011060	69912	16	chromosome, centromeric region kinetochore molecular_function nucleus nuclear pore nucleoplasm chromosome cytosol cell cycle chromosome segregation protein transport nuclear speck nuclear pore outer ring nuclear pore outer ring mRNA transport cell division	03013
TC0800001390.mm.2	Cenpn	centromere protein N	8	116921739	NM_028131, BC058243 NM_028131, BC058243	72155	14	chromosome, centromeric region kinetochore molecular_function nucleus nucleoplasm chromosome chromosome segregation kinetochore assembly
MG-1-neg-10338216_st
TC0200004808.mm.2	Thbd	thrombomodulin	2	-148404470	NM_009378, BC019154 NM_009378, BC019154	21824	120	transmembrane signaling receptor activity calcium ion binding extracellular space vacuolar membrane plasma membrane plasma membrane integral component of plasma membrane female pregnancy blood coagulation hemostasis embryo development external side of plasma membrane cell surface membrane integral component of membrane apicolateral plasma membrane negative regulation of blood coagulation negative regulation of coagulation	04610
TC0800002313.mm.2	Msmo1	methylsterol monoxygenase 1	8	-64718122	NM_025436, BC006802 NM_025436, BC006802	66234	31	C-4 methylsterol oxidase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process lipid biosynthetic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity	00100 01100
TC0X00003412.mm.2	Ccdc22	coiled-coil domain containing 22	X	-7593808	NM_138603, BC011195 NM_138603, BC011195	54638	17	protein binding endosome cellular copper ion homeostasis Golgi to plasma membrane transport cytoplasmic sequestering of NF-kappaB protein transport endocytic recycling cholesterol homeostasis positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling regulation of plasma lipoprotein particle levels cullin family protein binding cullin family protein binding retrograde transport, endosome to plasma membrane positive regulation of ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-dependent protein catabolic process
TC0600001462.mm.2	Vwf	Von Willebrand factor	6	125552947	NM_011708	22371	313	liver development placenta development protease binding integrin binding extracellular matrix structural constituent protein binding collagen binding extracellular region extracellular space extracellular space extracellular space cytoplasm endoplasmic reticulum cell adhesion blood coagulation blood coagulation blood coagulation hemostasis hemostasis hemostasis external side of plasma membrane immunoglobulin binding platelet activation extracellular matrix cell-substrate adhesion cell-substrate adhesion cell-substrate adhesion Weibel-Palade body identical protein binding protein N-terminus binding chaperone binding collagen-containing extracellular matrix collagen-containing extracellular matrix	04510 04512 04610
TC0100000858.mm.2	Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	1	89454810	NM_001037136, NM_178119, BC172673 NM_001037136, NM_178119, BC172673 NM_001037136, NM_178119, BC172673	347722	29	nucleotide binding GTPase activity GTPase activator activity GTP binding phospholipid binding nucleus cytoplasm cytosol protein transport metal ion binding	04144
TC0100002354.mm.2	Hspd1	heat shock protein 1 (chaperonin)	1	-55077833, -55077832	NM_010477, BC016400 NM_010477, BC016400	15510	137	nucleotide binding lipopolysaccharide binding lipopolysaccharide binding p53 binding MyD88-dependent toll-like receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell double-stranded RNA binding ATP binding extracellular space cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial matrix mitochondrial matrix early endosome peroxisomal matrix rough endoplasmic reticulum Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein folding activation of cysteine-type endopeptidase activity involved in apoptotic process response to unfolded protein high-density lipoprotein particle binding apoptotic mitochondrial changes apoptotic mitochondrial changes cell surface membrane isomerase activity enzyme binding mitochondrial crista coated vesicle secretory granule secretory granule ubiquitin protein ligase binding Golgi cisterna positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production protein-containing complex apolipoprotein binding apolipoprotein A-I binding mitochondrial unfolded protein response protein refolding B cell proliferation T cell activation T cell activation T cell activation T cell activation B cell activation zymogen granule positive regulation of macrophage activation positive regulation of apoptotic process negative regulation of apoptotic process myelin sheath intracellular membrane-bounded organelle negative regulation of neuron apoptotic process protein-containing complex binding protein import into mitochondrial intermembrane space membrane raft lipopolysaccharide receptor complex isotype switching to IgG isotypes positive regulation of inflammatory response protein stabilization positive regulation of T cell activation positive regulation of T cell activation positive regulation of T cell activation chaperone binding chaperone binding biological process involved in interaction with symbiont extracellular exosome negative regulation of apoptotic process in bone marrow cell cellular response to interleukin-7 modification-dependent protein binding negative regulation of reactive oxygen species biosynthetic process	03018 04940
TC0500002240.mm.2	Nop14	NOP14 nucleolar protein	5	-34638535	NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043	75416	21	nucleus nucleoplasm nucleolus nucleolus rRNA processing enzyme binding maturation of SSU-rRNA Noc4p-Nop14p complex small-subunit processome ribosome biogenesis
TC1600000335.mm.2	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	16	23226020, 23290469, 23224739	NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026	20440	78	Golgi trans cisterna Golgi membrane beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity extracellular region endoplasmic reticulum Golgi apparatus Golgi medial cisterna N-acetylneuraminate metabolic process protein glycosylation sialyltransferase activity sialyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine positive regulation of mononuclear cell proliferation protein homodimerization activity negative regulation of chemotaxis sialylation regulation of substrate adhesion-dependent cell spreading protein sialylation negative regulation of macrophage apoptotic process	00510 00514 01100
TC0100001656.mm.2	Exo1	exonuclease 1	1	175880777	NM_012012, BC006671 NM_012012, BC006671	26909	51	immune system process humoral immune response mediated by circulating immunoglobulin DNA binding chromatin binding catalytic activity nuclease activity endonuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane nucleobase-containing compound metabolic process DNA repair mismatch repair mismatch repair DNA recombination DNA recombination cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes nuclear body hydrolase activity hydrolase activity, acting on ester bonds 5'-flap endonuclease activity 5'-3' exodeoxyribonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity isotype switching metal ion binding flap endonuclease activity meiotic cell cycle double-stranded DNA 5'-3' exodeoxyribonuclease activity	03430
TC0100000351.mm.2	Wdr75	WD repeat domain 75	1	45795165	NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881	73674	23	nucleus nucleolus rRNA processing ribosome biogenesis positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing	03008
TC0500003219.mm.2	Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	5	-122731169	NM_001199676, NM_145358, BC023103 NM_001199676, NM_145358, BC023103 NM_001199676, NM_145358, BC023103	207565	67	nucleotide binding positive regulation of protein phosphorylation protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calcium ion binding protein binding calmodulin binding ATP binding nucleus cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity activation of protein kinase activity cell projection protein autophosphorylation CAMKK-AMPK signaling cascade	04920
TC0500002650.mm.2	Noa1	nitric oxide associated 1	5	-77294168	NM_019836, BC017154 NM_019836, BC017154	56412	24	nucleotide binding GTP binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane apoptotic process regulation of cell death regulation of cell death regulation of cell death membrane extrinsic component of mitochondrial inner membrane mitochondrial translation regulation of cellular respiration regulation of cellular respiration
TC1100003780.mm.2	Kat2a	K(lysine) acetyltransferase 2A	11	-100704745	NM_001038010, NM_020004, BC063752 NM_001038010, NM_020004, BC063752 NM_001038010, NM_020004, BC063752	14534	93	histone acetyltransferase complex histone acetyltransferase complex chromatin in utero embryonic development somitogenesis somitogenesis cytokine production neural tube closure chromatin binding chromatin binding transcription coactivator activity histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleus Ada2/Gcn5/Ada3 transcription activator complex Ada2/Gcn5/Ada3 transcription activator complex chromosome cytoplasm centrosome cytoskeleton regulation of transcription, DNA-templated nervous system development long-term memory N-acetyltransferase activity transcription factor binding transcription factor binding cell population proliferation H3 histone acetyltransferase activity H3 histone acetyltransferase activity acetyltransferase activity histone acetylation histone deubiquitination transferase activity transferase activity, transferring acyl groups internal peptidyl-lysine acetylation protein phosphatase binding telencephalon development metencephalon development midbrain development STAGA complex STAGA complex positive regulation of cell projection organization regulation of protein stability transcription factor TFTC complex positive regulation of histone acetylation multicellular organism growth histone deacetylase binding histone H3 acetylation histone H3 acetylation histone H4-K12 acetylation histone acetyltransferase activity (H4-K12 specific) histone H3-K14 acetylation oxoglutarate dehydrogenase complex regulation of regulatory T cell differentiation positive regulation of gluconeogenesis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of centriole replication regulation of synaptic plasticity intracellular distribution of mitochondria regulation of T cell activation regulation of cartilage development peptide-lysine-N-acetyltransferase activity alpha-tubulin acetylation mitotic spindle histone succinylation histone succinyltransferase activity peptidyl-lysine glutarylation histone glutaryltransferase activity regulation of bone development regulation of stem cell population maintenance positive regulation of cardiac muscle cell differentiation	04330
TSUnmapped00000020.mm.2	Snx29	sorting nexin 29	16	11322903, 11405647	NM_001290148	74478	15	molecular_function biological_process phosphatidylinositol binding
TC0400002854.mm.2	Tle1	transducin-like enhancer of split 1	4	-72157579, -72109944	NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573	21885	85	negative regulation of transcription by RNA polymerase II chromatin binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription factor binding positive regulation of gene expression Wnt signaling pathway identical protein binding negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of transcription, DNA-templated repressing transcription factor binding negative regulation of canonical Wnt signaling pathway beta-catenin-TCF complex negative regulation of anoikis
TC0700004201.mm.2	Cdr2	cerebellar degeneration-related 2	7	-120957039, -120957036	NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511	12585	20	molecular_function cytoplasm biological_process
TC0200001757.mm.2	Knl1	kinetochore scaffold 1	2	119047118, 119047118	NM_029617, BC080815 NM_029617, BC080815	76464	19	chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore acrosomal vesicle molecular_function nucleus nucleus nucleoplasm chromosome cell cycle chromosome segregation attachment of spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore negative regulation of phosphatase activity nuclear body protein localization to kinetochore protein localization to kinetochore cell division
TC0900002007.mm.2	Dcps	decapping enzyme, scavenger	9	-35124413	NM_027030, BC016273 NM_027030, BC016273	69305	22	deadenylation-dependent decapping of nuclear-transcribed mRNA RNA 7-methylguanosine cap binding RNA 7-methylguanosine cap binding P-body nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol mRNA processing RNA splicing hydrolase activity cellular response to menadione identical protein binding negative regulation of programmed cell death mRNA cis splicing, via spliceosome m7G(5')pppN diphosphatase activity m7G(5')pppN diphosphatase activity	03018
TC0700000786.mm.2	Klk1b11	kallikrein 1-related peptidase b11	7	43995876	NM_010640, BC013660 NM_010640, BC013660	16613	13	regulation of systemic arterial blood pressure endopeptidase activity serine-type endopeptidase activity extracellular space proteolysis peptidase activity serine-type peptidase activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides secretory granule zymogen activation protein-containing complex
TC1000002639.mm.2	Parpbp	PARP1 binding protein	10	-88091397	NM_029249, BC070476 NM_029249, BC070476	75317	21	chromatin chromatin DNA binding protein binding nucleus nucleoplasm cytoplasm DNA repair cellular response to DNA damage stimulus negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination
TC0700001989.mm.2	Lrrc27	leucine rich repeat containing 27	7	139212987, 139213274	NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816	76612	11	molecular_function
TC1500001742.mm.2	Top1mt	DNA topoisomerase 1, mitochondrial	15	-75657032	NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336	72960	21	DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity nucleoplasm chromosome mitochondrion mitochondrion DNA replication DNA topological change isomerase activity mitochondrial nucleoid mitochondrial nucleoid
TC0400001006.mm.2	Alg6	asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)	4	99715629	NM_001081264, BC050854 NM_001081264, BC050854	320438	15	endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity glucosyltransferase activity	00510 01100
TC0600003148.mm.2	Cd9	CD9 antigen	6	-125460265	NM_007657, BC070474, CD9 NM_007657, BC070474, CD9 NM_007657, BC070474, CD9	12527	130	integrin binding integrin binding protein binding extracellular region plasma membrane plasma membrane integral component of plasma membrane cell adhesion single fertilization fusion of sperm to egg plasma membrane involved in single fertilization fusion of sperm to egg plasma membrane involved in single fertilization negative regulation of cell population proliferation glial cell migration external side of plasma membrane cell surface myoblast fusion involved in skeletal muscle regeneration membrane integral component of membrane apical plasma membrane paranodal junction assembly receptor internalization protein-containing complex sperm-egg recognition negative regulation of cellular component movement extracellular exosome extracellular exosome cellular response to low-density lipoprotein particle stimulus negative regulation of platelet aggregation regulation of macrophage migration	04640
TC1800001654.mm.2	Rbfa	ribosome binding factor A	18	-80192263	NM_199197, BC064066 NM_199197, BC064066	68731	17	molecular_function cellular_component mitochondrion rRNA processing
TC0200002731.mm.2	Gm2026	predicted gene 2026	2	-175192004, -175419390, 175640390, 175737941, -176470368, -176619932	NM_001177543	100039060	9	cellular_component
TC0200001012.mm.2	Klhl23	kelch-like 23	2	69822369, 69821940, 69822840	NM_177784, BC072626 NM_177784, BC072626	277396	15
TC1000002043.mm.2					NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697			in utero embryonic development adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity protein binding cytosol cytosol polyamine biosynthetic process spermine biosynthetic process spermine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process lyase activity carboxy-lyase activity putrescine binding putrescine binding identical protein binding
TC1300001631.mm.2	H4c6	H4 clustered histone 6	13	-23551285	NM_175655, BC156748 NM_175655, BC156748	319157	5	nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation	05322
TC1700001163.mm.2	Ttc27	tetratricopeptide repeat domain 27	17	74717749	NM_152817, BC021912 NM_152817, BC021912	74196	18	molecular_function cellular_component biological_process
TC1200001834.mm.2	Mis18bp1	MIS18 binding protein 1	12	-65132734	NM_172578, BC052175 NM_172578, BC052175	217653	24	chromosome, centromeric region condensed nuclear chromosome kinetochore DNA binding protein binding nucleus chromosome cell cycle cell division
TC1700000657.mm.2	Lsm2	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated	17	34982129, 34981853, 34982129, 34981853	NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543	27756	32	spliceosomal tri-snRNP complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding protein binding nucleus nucleoplasm spliceosomal complex U6 snRNP cytoplasm mRNA processing mRNA catabolic process RNA splicing protein kinase binding small GTPase binding U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex	03018 03040
TC1600000238.mm.2	Trmt2a	TRM2 tRNA methyltransferase 2A	16	18248882	NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976	15547	40	nucleic acid binding RNA binding RNA processing methyltransferase activity RNA methyltransferase activity transferase activity methylation
TC0200004537.mm.2	Atp8b4	ATPase, class I, type 8B, member 4	2	-126320972, -126320972	NM_001080944	241633	12	Golgi apparatus trans-Golgi network plasma membrane plasma membrane Golgi organization phospholipid translocation ATPase-coupled intramembrane lipid transporter activity
TC0300000624.mm.2	4930579G24Rik	RIKEN cDNA 4930579G24 gene	3	79629078	NM_029482	75939	8	molecular_function cellular_component cytoplasm biological_process
TC1900001622.mm.2	Calhm2	calcium homeostasis modulator family member 2	19	-47132231	NM_133746, BC019197 NM_133746, BC019197	72691	13	cation channel activity integral component of plasma membrane ion transport membrane integral component of membrane positive regulation of apoptotic process
TC1200001012.mm.2	Rin3	Ras and Rab interactor 3	12	102283073, 102283640	NM_001161365, NM_177620, BC137907 NM_001161365, NM_177620, BC137907 NM_001161365, NM_177620, BC137907	217835	16	negative regulation of receptor internalization guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm endosome early endosome signal transduction endocytic vesicle axon dendrite small GTPase binding cytoplasmic vesicle vesicle neuronal cell body negative regulation of mast cell chemotaxis regulation of vesicle size
TC0200004376.mm.2	Dph6	diphthamine biosynthesis 6	2	-114516417	NM_025675, BC022995 NM_025675, BC022995	66632	17	nucleotide binding ATP binding nucleoplasm nucleolus ligase activity diphthine-ammonia ligase activity diphthine-ammonia ligase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine
MG-1-neg-10339930_st
TC1300001635.mm.2	H2bc7	H2B clustered histone 7	13	-23573759	NM_178195, BC160307 NM_178195, BC160307	319180	6	innate immune response in mucosa DNA binding extracellular space nucleoplasm cytosol nucleosome assembly antibacterial humoral response identical protein binding defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide	05322
TC0200005271.mm.2	Aurka	aurora kinase A	2	-172356189	NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711	20878	115	nucleotide binding meiotic spindle organization microtubule cytoskeleton organization mitotic cell cycle protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm cytoplasm centrosome centrosome microtubule organizing center spindle cytosol cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cilium protein phosphorylation protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle organization spindle assembly involved in female meiosis I centrosome cycle mitotic centrosome separation mitotic centrosome separation response to wounding anterior/posterior axis specification negative regulation of gene expression microtubule cytoskeleton kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation protein kinase binding cell projection organization spindle pole centrosome spindle pole centrosome ubiquitin protein ligase binding regulation of protein stability negative regulation of protein binding chromosome passenger complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis histone serine kinase activity histone serine kinase activity germinal vesicle cell projection negative regulation of apoptotic process axon hillock pronucleus protein heterodimerization activity perinuclear region of cytoplasm spindle midzone cell division meiotic cell cycle centrosome localization protein localization to centrosome mitotic spindle meiotic spindle negative regulation of spindle checkpoint liver regeneration mitotic spindle pole positive regulation of oocyte maturation neuron projection extension	04114
TC1500001823.mm.2	Foxred2	FAD-dependent oxidoreductase domain containing 2	15	-77940521	NM_001017983, NM_001168260, BC086662 NM_001017983, NM_001168260, BC086662 NM_001017983, NM_001168260, BC086662	239554	12	endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum lumen oxidoreductase activity ubiquitin-dependent ERAD pathway ubiquitin-dependent ERAD pathway flavin adenine dinucleotide binding
TC1000002443.mm.2	Pwp2	PWP2 periodic tryptophan protein homolog (yeast)	10	-78170909	NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480	110816	23	ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus small-subunit processome Pwp2p-containing subcomplex of 90S preribosome	03008
TC1900001472.mm.2	Noc3l	NOC3 like DNA replication regulator	19	-38788127	NM_021315, BC031132 NM_021315, BC031132	57753	29	chromatin binding nucleus nucleoplasm nucleolus nucleolus nucleolus mitochondrion DNA replication initiation nuclear speck fat cell differentiation
TC0500002095.mm.2	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	5	-24862734, -24862734, -24862734	NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283	108099	37	nucleotide binding AMP-activated protein kinase activity AMP-activated protein kinase activity cAMP-dependent protein kinase inhibitor activity ATP binding nucleus nucleoplasm cytoplasm cytosol glycogen metabolic process regulation of glycolytic process protein phosphorylation negative regulation of protein kinase activity lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process cAMP-dependent protein kinase regulator activity phosphorylase kinase regulator activity positive regulation of peptidyl-threonine phosphorylation AMP binding AMP binding regulation of fatty acid metabolic process protein kinase regulator activity protein kinase binding protein kinase binding protein kinase activator activity nucleotide-activated protein kinase complex nucleotide-activated protein kinase complex adenyl ribonucleotide binding intracellular signal transduction cellular response to glucose starvation ADP binding positive regulation of protein kinase activity regulation of catalytic activity regulation of catalytic activity regulation of protein serine/threonine kinase activity	04910 04920 05410
TC0300002352.mm.2	Cks1b	CDC28 protein kinase 1b	3	-89415471	NM_016904, BC076579 NM_016904, BC076579	54124	38	cyclin-dependent protein kinase holoenzyme complex regulation of transcription, DNA-templated cell cycle regulation of mitotic cell cycle cell population proliferation embryo development cyclin-dependent protein serine/threonine kinase regulator activity SCF ubiquitin ligase complex protein kinase binding histone binding ubiquitin binding mitotic cell cycle phase transition cell division cyclin-dependent protein serine/threonine kinase activator activity	05200 05222
TC0100003477.mm.2
TC1200000988.mm.2	Tdp1	tyrosyl-DNA phosphodiesterase 1	12	99884517, 99884517	NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162	104884	35	single strand break repair single strand break repair single strand break repair double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding nuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane DNA repair DNA repair double-strand break repair double-strand break repair cellular response to DNA damage stimulus phosphoric diester hydrolase activity hydrolase activity 3'-tyrosyl-DNA phosphodiesterase activity 3'-tyrosyl-DNA phosphodiesterase activity intracellular membrane-bounded organelle
TC0200001881.mm.2	Dut	deoxyuridine triphosphatase	2	125247247, 125247514	NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693	110074	32	magnesium ion binding dUTP diphosphatase activity dUTP diphosphatase activity nucleus nucleoplasm cytoplasm mitochondrion cytosol dUMP biosynthetic process dUMP biosynthetic process receptor inhibitor activity pyrimidine deoxyribonucleotide binding identical protein binding peroxisome proliferator activated receptor binding regulation of protein-containing complex assembly dUTP catabolic process dUTP catabolic process	00240 01100
TC0100003021.mm.2	Zranb3	zinc finger, RAN-binding domain containing 3	1	-127954178, -127954178, -127954178	NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922	226409	20	nucleotide binding nucleic acid binding catalytic activity helicase activity nuclease activity endonuclease activity endodeoxyribonuclease activity endodeoxyribonuclease activity ATP binding nucleus nucleoplasm chromosome DNA repair DNA repair cellular response to DNA damage stimulus metabolic process response to UV hydrolase activity replication fork processing replication fork processing DNA rewinding annealing helicase activity nuclear replication fork nuclear replication fork negative regulation of DNA recombination metal ion binding replication fork protection replication fork protection K63-linked polyubiquitin modification-dependent protein binding
TC1700002795.mm.2					NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983			molecular_function protein binding cellular_component cytosol cytoplasmic dynein complex microtubule-based movement biological_process extrinsic component of membrane sperm flagellum
TC0X00001323.mm.2	Bex3	brain expressed X-linked 3	X	136270252	NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815	12070	35	signaling receptor binding death receptor binding nucleus cytoplasm cytoplasm cytosol cytosol cytosol apoptotic process signal transduction extrinsic apoptotic signaling pathway via death domain receptors identical protein binding metal ion binding	04722
TC0200005339.mm.2					NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process
TC0800002529.mm.2	Gab1	growth factor receptor bound protein 2-associated protein 1	8	-80764433, -80764430	NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659	14388	95	activation of MAPK activity angiogenesis protein binding cytoplasm cytosol cell-cell junction response to oxidative stress signal transduction epidermal growth factor receptor signaling pathway activation of JUN kinase activity heart development epidermis development regulation of cell migration actin cytoskeleton reorganization response to hepatocyte growth factor cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor signaling pathway positive regulation of cell migration by vascular endothelial growth factor signaling pathway positive regulation of MAPK cascade positive regulation of angiogenesis platelet-derived growth factor receptor signaling pathway labyrinthine layer development interleukin-6-mediated signaling pathway endothelial cell chemotaxis to vascular endothelial growth factor	04012 04722 05100 05211
TC0200001002.mm.2	Nostrin	nitric oxide synthase trafficker	2	69135799	NM_181547, BC069942 NM_181547, BC069942	329416	17	DNA binding protein binding nucleus cytoplasm cytoskeleton plasma membrane endocytosis signal transduction membrane cytoplasmic vesicle negative regulation of transcription, DNA-templated
TC0700001343.mm.2	Nars2	asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)	7	96951526	NM_153591, BC030041 NM_153591, BC030041	244141	18	nucleotide binding nucleic acid binding aminoacyl-tRNA ligase activity asparagine-tRNA ligase activity ATP binding nucleoplasm mitochondrion mitochondrion cytosol translation tRNA aminoacylation for protein translation asparaginyl-tRNA aminoacylation ligase activity	00970
TC0200005350.mm.2					NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process
TC1100004056.mm.2					XR_106365
TC1200001908.mm.2	Dhrs7	dehydrogenase/reductase (SDR family) member 7	12	-72650352	NM_025522, BC016189 NM_025522, BC016189	66375	18	biological_process oxidoreductase activity
TC0800000371.mm.2	Fut10	fucosyltransferase 10	8	31187330, 31187330	NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113	171167	17	Golgi membrane nucleoplasm endoplasmic reticulum Golgi apparatus protein glycosylation fucosyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups cerebral cortex radially oriented cell migration fucosylation alpha-(1->3)-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity neuronal stem cell population maintenance
TC1100003941.mm.2	Kpna2	karyopherin (importin) alpha 2	11	-106988628	NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011	16647	97	protein binding nucleus nucleoplasm nucleoplasm nucleoplasm cytosol cytosol protein import into nucleus NLS-bearing protein import into nucleus NLS-bearing protein import into nucleus nuclear localization sequence binding nuclear localization sequence binding cytoplasmic stress granule histone deacetylase binding nuclear import signal receptor activity nuclear import signal receptor activity repressing transcription factor binding entry of viral genome into host nucleus through nuclear pore complex via importin entry of viral genome into host nucleus through nuclear pore complex via importin extrinsic component of postsynaptic specialization membrane glutamatergic synapse postsynapse to nucleus signaling pathway positive regulation of viral life cycle positive regulation of viral life cycle
TC0800000912.mm.2	Rnf150	ring finger protein 150	8	82863355	NM_177378, BC160221 NM_177378, BC160221	330812	10	cytoplasm ubiquitin-dependent protein catabolic process membrane integral component of membrane metal ion binding ubiquitin protein ligase activity
TC1200001861.mm.2	Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	12	-69201778	NM_011133, BC063772 NM_011133, BC063772	18974	23	DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA replication DNA-dependent DNA replication epsilon DNA polymerase complex epsilon DNA polymerase complex nuclear body error-prone translesion synthesis intracellular membrane-bounded organelle	00230 00240 01100 03030 03410 03420
TC0400000567.mm.2	Smc2	structural maintenance of chromosomes 2	4	52439220	NM_008017, BC094380 NM_008017, BC094380	14211	37	single strand break repair nucleotide binding nuclear chromosome condensed chromosome condensed chromosome condensin complex condensin complex condensin complex condensin complex chromatin binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cell cycle mitotic chromosome condensation meiotic chromosome condensation chromosome condensation meiotic chromosome segregation chromosome organization cell division kinetochore organization
TC0500003418.mm.2	Cux1	cut-like homeobox 1	5	-136248134, -136266409, -136266409, -136248134	NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847	13047	445	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific kidney development DNA binding chromatin binding nucleus nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II intra-Golgi vesicle-mediated transport multicellular organism development membrane integral component of membrane integral component of Golgi membrane lung development inner ear auditory receptor cell differentiation neuron projection sequence-specific DNA binding positive regulation of dendrite morphogenesis
TC0500002059.mm.2	Pus7	pseudouridylate synthase 7	5	-23740164, -23740164	NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316	78697	18	pseudouridine synthesis RNA binding nucleus nucleus tRNA processing RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity negative regulation of translation enzyme binding tRNA pseudouridine synthesis regulation of hematopoietic stem cell differentiation mRNA pseudouridine synthesis regulation of mesoderm development
TC0700004188.mm.2	Thumpd1	THUMP domain containing 1	7	-119715093	NM_145585, BC004776 NM_145585, BC004776	233802	21	RNA binding cellular_component tRNA modification
TC1000001601.mm.2					NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908			molecular_function cellular_component biological_process
TC1800001368.mm.2	Marchf3	membrane associated ring-CH-type finger 3	18	-56761715, -56775146	NM_177115, BC107232, BC107233 NM_177115, BC107232, BC107233 NM_177115, BC107232, BC107233	320253	15	ubiquitin-protein transferase activity lysosome endosome endocytosis zinc ion binding membrane integral component of membrane protein ubiquitination transferase activity cytoplasmic vesicle intracellular membrane-bounded organelle metal ion binding
TC0300003226.mm.2	Gm5150	predicted gene 5150	3	-15948069	NM_001081687, BC156687 NM_001081687, BC156687	381484	3	molecular_function plasma membrane positive regulation of phagocytosis positive regulation of T cell activation
TC0700001442.mm.2	Anapc15	anaphase promoting complex C subunit 15	7	101881324, 101896330, 101885859	NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730	75430	20	molecular_function anaphase-promoting complex cell cycle cell division regulation of mitotic cell cycle spindle assembly checkpoint
TC1500001300.mm.2	Otulinl	OTU deubiquitinase with linear linkage specificity like	15	-27655070	NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328	223433	15	molecular_function nucleus nuclear envelope cytoplasm endoplasmic reticulum biological_process membrane extrinsic component of endoplasmic reticulum membrane
TC1600000464.mm.2	Osbpl11	oxysterol binding protein-like 11	16	33185070	NM_176840, BC035278 NM_176840, BC035278	106326	25	nucleoplasm endosome Golgi apparatus cytosol lipid transport lipid binding positive regulation of sequestering of triglyceride sterol transporter activity membrane sterol binding intracellular membrane-bounded organelle fat cell differentiation
TC1700002286.mm.2	Sgo1	shugoshin 1	17	-53674786	NM_028232, BC089014 NM_028232, BC089014	72415	41	mitotic sister chromatid segregation chromosome, centromeric region chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region spindle pole nucleus nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton cell cycle chromosome segregation attachment of spindle microtubules to kinetochore centriole-centriole cohesion centriole-centriole cohesion kinase binding meiotic chromosome segregation homologous chromosome segregation meiotic sister chromatid cohesion cell division mitotic sister chromatid cohesion, centromeric	04114
TC0200004665.mm.2	Rassf2	Ras association (RalGDS/AF-6) domain family member 2	2	-131992849, -131992849	NM_175445, BC057402 NM_175445, BC057402	215653	22	chromosome, centromeric region kinetochore skeletal system development ossification protein kinase activity protein binding nucleus nucleus nucleus nucleoplasm chromosome cytoplasm cytoplasm cytoplasm Golgi apparatus cytosol plasma membrane cell cycle signal transduction positive regulation of protein autophosphorylation protein-containing complex negative regulation of peptidyl-serine phosphorylation epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade regulation of apoptotic process positive regulation of apoptotic process regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein kinase activity positive regulation of protein kinase activity positive regulation of JNK cascade positive regulation of JNK cascade bone remodeling homeostasis of number of cells protein stabilization regulation of NIK/NF-kappaB signaling regulation of NIK/NF-kappaB signaling negative regulation of NIK/NF-kappaB signaling
TC0100000399.mm.2	Mars2	methionine-tRNA synthetase 2 (mitochondrial)	1	55237176	NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739	212679	20	nucleotide binding aminoacyl-tRNA ligase activity methionine-tRNA ligase activity methionine-tRNA ligase activity ATP binding mitochondrion mitochondrial matrix translation tRNA aminoacylation for protein translation methionyl-tRNA aminoacylation methionyl-tRNA aminoacylation ligase activity	00450 00970
TC0400000501.mm.2	Ncbp1	nuclear cap binding protein subunit 1	4	46138510	NM_001033201, BC138898 NM_001033201, BC138898	433702	29	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay spliceosomal complex assembly RNA cap binding RNA 7-methylguanosine cap binding RNA binding mRNA binding protein binding nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol mRNA cap binding complex mRNA cap binding complex nuclear cap binding complex nuclear cap binding complex 7-methylguanosine mRNA capping mRNA processing RNA catabolic process mRNA export from nucleus mRNA export from nucleus regulation of translation regulation of translational initiation RNA splicing RNA metabolic process positive regulation of cell growth gene silencing by RNA positive regulation of mRNA 3'-end processing RNA cap binding complex mRNA cis splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome regulation of mRNA processing mRNA transport pre-mRNA cleavage required for polyadenylation positive regulation of RNA binding ribonucleoprotein complex	03013 03015 03040
TC0500001853.mm.2	B3glct	beta-3-glucosyltransferase	5	149678229	NM_001081204	381694	19	cellular_component endoplasmic reticulum carbohydrate metabolic process fucose metabolic process biological_process acetylglucosaminyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups	00514
TC0900001005.mm.2	Fam214a	family with sequence similarity 214, member A	9	74952879, 74976110, 74953052	NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353	235493	15	molecular_function cellular_component biological_process
TC0100000471.mm.2	Abi2	abl interactor 2	1	60409618	NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646	329165	33	cytoplasm cytosol cytoskeleton actin filament adherens junction adherens junction nervous system development learning or memory actin polymerization or depolymerization positive regulation of lamellipodium assembly dendrite development cell migration Rac protein signal transduction SH3 domain binding SH3 domain binding peptidyl-tyrosine phosphorylation lamellipodium lamellipodium cell junction dendrite SCAR complex small GTPase binding ubiquitin protein ligase binding filopodium tip signaling adaptor activity identical protein binding cell projection camera-type eye development dendritic spine zonula adherens assembly synapse regulation of dendritic spine morphogenesis proline-rich region binding lens fiber cell morphogenesis postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton organization postsynaptic actin cytoskeleton organization glutamatergic synapse glutamatergic synapse positive regulation of Arp2/3 complex-mediated actin nucleation	04810
MG-1-neg-10338901_st
TC1000000566.mm.2	Lrrc20	leucine rich repeat containing 20	10	61475832	NM_153542, BC036304 NM_153542, BC036304	216011	15	molecular_function cellular_component biological_process
TC0200002668.mm.2	Cass4	Cas scaffolding protein family member 4	2	172393643	NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538	320664	13	cytoplasm cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway cell migration cell junction positive regulation of cell migration positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity actin filament reorganization positive regulation of substrate adhesion-dependent cell spreading protein tyrosine kinase binding
TC1400001931.mm.2	Wdhd1	WD repeat and HMG-box DNA binding protein 1	14	-47240943	NM_172598, BC063740 NM_172598, BC063740	218973	22	mitotic cell cycle chromosome, centromeric region DNA binding chromatin binding chromatin binding RNA binding protein binding nucleus nucleoplasm DNA-dependent DNA replication DNA repair RNA processing regulation of chromosome organization nuclear replication fork RNA polymerase binding heterochromatin maintenance
TC1400000347.mm.2	Ercc6	excision repair cross-complementing rodent repair deficiency, complementation group 6	14	32513520	NM_001081221, BC167234 NM_001081221, BC167234	319955	84	single strand break repair DNA damage checkpoint nucleotide binding response to superoxide positive regulation of defense response to virus by host DNA binding chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus DNA repair DNA repair DNA repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair base-excision repair pyrimidine dimer repair transcription elongation from RNA polymerase I promoter cellular response to DNA damage stimulus response to oxidative stress response to oxidative stress activation of JNKK activity activation of JUN kinase activity nervous system development protein C-terminus binding transcription elongation factor complex DNA-dependent ATPase activity DNA-dependent ATPase activity intrinsic apoptotic signaling pathway in response to DNA damage response to UV response to UV response to toxic substance response to X-ray response to UV-B response to gamma radiation positive regulation of gene expression nuclear body hydrolase activity neurogenesis neuron differentiation protein tyrosine kinase activator activity neuron projection development regulation of DNA-templated transcription, elongation positive regulation of DNA-templated transcription, elongation positive regulation of peptidyl-serine phosphorylation of STAT protein multicellular organism growth ATP-dependent chromatin remodeling sequence-specific DNA binding protein-containing complex binding photoreceptor cell maintenance positive regulation of DNA repair protein N-terminus binding positive regulation of transcription initiation from RNA polymerase II promoter positive regulation of transcription initiation from RNA polymerase II promoter RNA polymerase binding site of DNA damage double-strand break repair via classical nonhomologous end joining positive regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via nonhomologous end joining	03420
TC1000000312.mm.2	Hdac2	histone deacetylase 2	10	36974543	NM_008229, BC138517 NM_008229, BC138517	15182	299	histone deacetylase complex histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor binding chromatin binding histone deacetylase activity histone deacetylase activity histone deacetylase activity histone deacetylase activity protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork transcription regulator complex cytoplasm cytoplasm chromatin organization protein deacetylation transcription factor binding transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation epidermal cell differentiation positive regulation of epithelial to mesenchymal transition negative regulation of neuron projection development negative regulation of neuron projection development dendrite development histone deacetylation histone deacetylation Sin3 complex NuRD complex hydrolase activity transcription repressor complex deacetylase activity deacetylase activity enzyme binding enzyme binding hippocampus development neuron differentiation heat shock protein binding chromatin DNA binding NAD-dependent histone deacetylase activity (H3-K14 specific) positive regulation of interleukin-1 production positive regulation of tumor necrosis factor production circadian regulation of gene expression protein-containing complex protein deacetylase activity protein deacetylase activity histone deacetylase activity (H4-K16 specific) ESC/E(Z) complex Krueppel-associated box domain binding cellular response to trichostatin A odontogenesis of dentin-containing tooth positive regulation of tyrosine phosphorylation of STAT protein embryonic digit morphogenesis histone deacetylase binding negative regulation of apoptotic process negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding positive regulation of proteolysis negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II rhythmic process positive regulation of oligodendrocyte differentiation positive regulation of oligodendrocyte differentiation NF-kappaB binding positive regulation of DNA-binding transcription factor activity regulation of protein kinase B signaling cardiac muscle cell development negative regulation of cardiac muscle cell proliferation regulation of sarcomere organization hair follicle placode formation negative regulation of dendritic spine development eyelid development in camera-type eye fungiform papilla formation cellular response to hydrogen peroxide histone H3-K27 methylation heterochromatin maintenance histone H3 deacetylation histone H3 deacetylation histone H3 deacetylation histone H4 deacetylation histone H4 deacetylation negative regulation of canonical Wnt signaling pathway regulation of protein deacetylation RNA polymerase II transcription repressor complex positive regulation of male mating behavior negative regulation of pri-miRNA transcription by RNA polymerase II negative regulation of pri-miRNA transcription by RNA polymerase II promoter-specific chromatin binding positive regulation of signaling receptor activity negative regulation of peptidyl-lysine acetylation negative regulation of intrinsic apoptotic signaling pathway	04110 04330 05016 05200 05220
TC1300000626.mm.2	Simc1	SUMO-interacting motifs containing 1	13	54503804	NM_176987, BC167252 NM_176987, BC167252	319719	12	cytoplasm biological_process sarcomere peptidase inhibitor activity SUMO polymer binding SUMO polymer binding
TC0700003075.mm.2	E2f8	E2F transcription factor 8	7	-48866428, -48866428	NM_001013368, BC086675, E2F NM_001013368, BC086675, E2F NM_001013368, BC086675, E2F	108961	43	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific placenta development sprouting angiogenesis sprouting angiogenesis DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleoplasm transcription regulator complex nucleolus cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle cell population proliferation negative regulation of cytokinesis positive regulation of DNA endoreduplication cell cycle comprising mitosis without cytokinesis identical protein binding positive regulation of transcription by RNA polymerase II trophoblast giant cell differentiation chorionic trophoblast cell differentiation hepatocyte differentiation RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding
TC1100000021.mm.2	Morc2a	microrchidia 2A	11	3649436, 3658671	NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243	74522	25	nucleotide binding magnesium ion binding heterochromatin chromatin binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytosol chromatin remodeling cellular response to DNA damage stimulus zinc ion binding nuclear matrix hydrolase activity ATPase activity histone binding protein homodimerization activity negative regulation of gene expression, epigenetic negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate metal ion binding positive regulation of DNA methylation-dependent heterochromatin assembly positive regulation of DNA methylation-dependent heterochromatin assembly
TC1200000348.mm.2	Etv1	ets variant 1	12	38783710, 38780081	NM_001163154, NM_007960, BC005645 NM_001163154, NM_007960, BC005645 NM_001163154, NM_007960, BC005645	14009	289	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II axon guidance muscle organ development mechanosensory behavior cell differentiation sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II peripheral nervous system neuron development sequence-specific double-stranded DNA binding
TC0700001906.mm.2	Tacc2	transforming, acidic coiled-coil containing protein 2	7	130577437, 130692617	NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856	57752	33	microtubule cytoskeleton organization microtubule cytoskeleton organization nucleus nucleoplasm cytoplasm cytosol cytoskeleton plasma membrane mitotic spindle organization cell population proliferation cell population proliferation protein domain specific binding cerebral cortex development cerebral cortex development neurogenesis interkinetic nuclear migration astral microtubule organization regulation of microtubule-based process nuclear hormone receptor binding
TC1000000191.mm.2	Slc18b1	solute carrier family 18, subfamily B, member 1	10	23796985	NM_183116	76306	17	membrane integral component of membrane transmembrane transporter activity
TC0100002963.mm.2	Tmem37	transmembrane protein 37	1	-120067376	NM_019432, BC024613 NM_019432, BC024613	170706	20	voltage-gated ion channel activity calcium channel activity ion transport calcium ion transport membrane integral component of membrane regulation of ion transmembrane transport calcium ion transmembrane transport
TC0900003168.mm.2	Crtap	cartilage associated protein	9	-114375130	NM_019922, BC049890 NM_019922, BC049890	56693	28	collagen binding extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum spermatogenesis peptidyl-proline hydroxylation to 3-hydroxy-L-proline peptidyl-proline hydroxylation to 3-hydroxy-L-proline collagen fibril organization protein stabilization negative regulation of post-translational protein modification
TC0600000127.mm.2	Cav2	caveolin 2	6	17281184, 17281184	NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095	12390	68	SNARE binding negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation acrosomal membrane caveolar macromolecular signaling complex protein binding nucleus nuclear envelope nuclear inner membrane cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus lipid droplet cytosol plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola caveola caveola focal adhesion focal adhesion focal adhesion endocytosis vesicle fusion vesicle fusion mitochondrion organization endoplasmic reticulum organization chemical synaptic transmission negative regulation of cell population proliferation insulin receptor signaling pathway insulin receptor signaling pathway cell surface membrane membrane vesicle organization receptor-mediated endocytosis of virus by host cell protein kinase binding protein kinase binding protein kinase binding syntaxin binding transport vesicle cell differentiation negative regulation of transforming growth factor beta receptor signaling pathway protein-macromolecule adaptor activity extrinsic component of cytoplasmic side of plasma membrane extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cytoplasmic vesicle mitogen-activated protein kinase kinase kinase binding D1 dopamine receptor binding D1 dopamine receptor binding protein-containing complex protein-containing complex sarcolemma protein homodimerization activity positive regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation by host of viral release from host cell positive regulation by host of viral process membrane raft protein heterodimerization activity vesicle docking vesicle docking perinuclear region of cytoplasm perinuclear region of cytoplasm perinuclear region of cytoplasm skeletal muscle fiber development positive regulation of peptidyl-tyrosine phosphorylation phosphoprotein binding regulation of cytosolic calcium ion concentration molecular adaptor activity molecular adaptor activity positive regulation of dopamine receptor signaling pathway positive regulation of dopamine receptor signaling pathway caveola assembly caveola assembly caveola assembly basement membrane organization scaffold protein binding positive regulation of protein localization to nucleus	04144 04510 05100
TC0X00001674.mm.2	Fancb	Fanconi anemia, complementation group B	X	164980591	NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151	237211	17	molecular_function nucleus DNA repair cellular response to DNA damage stimulus cellular response to drug cellular response to drug interstrand cross-link repair Fanconi anaemia nuclear complex Fanconi anaemia nuclear complex cellular response to camptothecin positive regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair via homologous recombination replication-born double-strand break repair via sister chromatid exchange replication-born double-strand break repair via sister chromatid exchange negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination
TC1600000440.mm.2	Tm4sf19	transmembrane 4 L six family member 19	16	32400505	NM_001160402, BC147727, BC147729 NM_001160402, BC147727, BC147729 NM_001160402, BC147727, BC147729	277203	4	molecular_function biological_process integral component of membrane
TC0600001027.mm.2	Rpn1	ribophorin I	6	88084472	NM_133933, BC016080 NM_133933, BC016080	103963	35	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum endoplasmic reticulum membrane rough endoplasmic reticulum rough endoplasmic reticulum cytosol protein glycosylation protein N-linked glycosylation oligosaccharyltransferase complex oligosaccharyltransferase complex membrane integral component of membrane protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine	00510 01100 04141
TC1400002387.mm.2
TC0900002367.mm.2	1700017B05Rik	RIKEN cDNA 1700017B05 gene	9	-57252321	NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965	74211	16	molecular_function cytosol biological_process
TC0300001478.mm.2	Znhit6	zinc finger, HIT type 6	3	145576215, 145576207	NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198	229937	13	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) box C/D snoRNP assembly box C/D snoRNP assembly TFIID-class transcription factor complex binding nucleus enzyme binding ribosome biogenesis identical protein binding metal ion binding snoRNA localization snoRNA localization ATPase binding protein complex oligomerization pre-snoRNP complex pre-snoRNP complex
TC0900002047.mm.2	Ccdc15	coiled-coil domain containing 15	9	-37267463	NM_001081429	245902	12	molecular_function centrosome centrosome biological_process
TC1200002092.mm.2	Acyp1	acylphosphatase 1, erythrocyte (common) type	12	-85272397, -85278893, -85272397	NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783	66204	13	acylphosphatase activity biological_process hydrolase activity	00620
MG-1-neg-10341270_st
TC0900002489.mm.2	Zwilch	zwilch kinetochore protein	9	-64137143	NM_026507, BC027435 NM_026507, BC027435	68014	18	chromosome, centromeric region kinetochore molecular_function chromosome cell cycle mitotic cell cycle checkpoint protein localization to kinetochore cell division signal transduction involved in mitotic cell cycle checkpoint RZZ complex
TC1300002766.mm.2	Nsun2	NOL1/NOP2/Sun domain family member 2	13	69612015	NM_145354, BC013625 NM_145354, BC013625	28114	49	tRNA binding RNA methylation in utero embryonic development RNA binding extracellular region nucleus nucleolus cytoplasm cytoplasm mitochondrion cytoskeleton cell cycle spermatogenesis spermatid development tRNA processing methyltransferase activity regulation of mRNA export from nucleus tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity transferase activity cell differentiation tRNA methylation tRNA methylation tRNA methylation tRNA methylation methylation meiotic cell cycle checkpoint chromatoid body tRNA stabilization hair follicle maturation cell division mRNA (cytidine-5-)-methyltransferase activity mRNA (cytidine-5-)-methyltransferase activity extracellular exosome mRNA methylation mRNA methylation regulation of stem cell differentiation
TC0200001546.mm.2	Lmo2	LIM domain only 2	2	103969556, 103970286, 103957994	NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880	16909	110	RNA polymerase II activating transcription factor binding transcription coregulator binding DNA binding chromatin binding transcription coactivator activity protein binding nucleus transcription regulator complex transcription factor binding protein-containing complex embryonic hemopoiesis identical protein binding bHLH transcription factor binding negative regulation of erythrocyte differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cellular response to thyroid hormone stimulus
MG-1-pos-10338865_st
TC1500001653.mm.2	Tmem71	transmembrane protein 71	15	-66526211	NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824	213068	13	molecular_function mitochondrion biological_process membrane integral component of membrane
TC1900001619.mm.2	Pcgf6	polycomb group ring finger 6	19	-47033616	NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460	71041	35	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II protein binding nucleus nucleus regulation of transcription by RNA polymerase II protein domain specific binding PcG protein complex PcG protein complex PRC1 complex PRC1 complex histone H2A-K119 monoubiquitination histone H2A-K119 monoubiquitination negative regulation of transcription, DNA-templated metal ion binding
TC1400002260.mm.2	Esco2	establishment of sister chromatid cohesion N-acetyltransferase 2	14	-65819026	NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275	71988	35	chromatin XY body hematopoietic progenitor cell differentiation lysine N-acetyltransferase activity, acting on acetyl phosphate as donor nucleus nucleoplasm chromosome pericentric heterochromatin Golgi apparatus regulation of DNA replication regulation of DNA replication double-strand break repair cell cycle chromosome segregation sister chromatid cohesion chromocenter acetyltransferase activity transferase activity transferase activity, transferring acyl groups cell junction post-translational protein acetylation post-translational protein acetylation site of double-strand break metal ion binding protein localization to chromatin
TC1400000862.mm.2	Arl11	ADP-ribosylation factor-like 11	14	61309752	NM_177337, BC064093 NM_177337, BC064093	219144	13	nucleotide binding hematopoietic progenitor cell differentiation GTP binding cytoplasm plasma membrane intracellular protein transport vesicle-mediated transport
TC1100002740.mm.2	Rad50	RAD50 double strand break repair protein	11	-53649518	NM_009012, BC168398 NM_009012, BC168398	19360	68	single-stranded DNA endodeoxyribonuclease activity regulation of mitotic recombination nucleotide binding telomere maintenance via recombination telomere maintenance chromosome, telomeric region chromatin condensed nuclear chromosome condensed nuclear chromosome DNA binding DNA helicase activity double-stranded DNA binding double-stranded telomeric DNA binding ATP binding nucleus nucleoplasm chromosome DNA repair double-strand break repair double-strand break repair DNA recombination cellular response to DNA damage stimulus telomere maintenance via telomerase telomere maintenance via telomerase cell cycle regulation of mitotic cell cycle 3'-5' exonuclease activity inclusion body hydrolase activity ATPase activity protein-macromolecule adaptor activity Mre11 complex Mre11 complex telomeric 3' overhang formation positive regulation of protein autophosphorylation positive regulation of telomere maintenance DNA duplex unwinding DNA duplex unwinding positive regulation of kinase activity site of double-strand break identical protein binding single-stranded telomeric DNA binding protein-containing complex binding pronucleus negative regulation of viral entry into host cell metal ion binding perinuclear region of cytoplasm chromosome organization meiotic cell cycle G-quadruplex DNA binding chromosome organization involved in meiotic cell cycle chromosome organization involved in meiotic cell cycle nucleic acid phosphodiester bond hydrolysis negative regulation of telomere capping	03440 03450
TC0100001853.mm.2	Ints7	integrator complex subunit 7	1	191575635	NM_178632, BC054120 NM_178632, BC054120	77065	25	DNA damage checkpoint molecular_function nucleus chromosome cytoplasm cellular response to DNA damage stimulus snRNA processing nuclear body integrator complex integrator complex snRNA 3'-end processing cellular response to ionizing radiation
TC0700003608.mm.2	Cpeb1	cytoplasmic polyadenylation element binding protein 1	7	-81347025, -81347025	NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476	12877	64	translation repressor activity, mRNA regulatory element binding translation repressor activity, mRNA regulatory element binding nucleic acid binding RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm centrosome cytosol mRNA processing regulation of translation synaptonemal complex assembly translation factor activity, RNA binding negative regulation of cell population proliferation positive regulation of neuron projection development postsynaptic density membrane negative regulation of translation cell junction positive regulation of cell migration growth cone cellular response to insulin stimulus mRNA 3'-UTR AU-rich region binding neuron projection ribosome binding neuronal cell body translation regulator activity synapse positive regulation of translation metal ion binding regulation of neuronal synaptic plasticity perinuclear region of cytoplasm mRNA transport positive regulation of nitric-oxide synthase biosynthetic process cellular response to amino acid stimulus cellular response to hypoxia cellular response to hypoxia meiotic spindle positive regulation of mRNA polyadenylation messenger ribonucleoprotein complex negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation	04114 04320 04914
TC0500000050.mm.2	Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	5	8567090	NM_011076	18671	275	G2/M transition of mitotic cell cycle nucleotide binding ATP binding nucleoplasm plasma membrane plasma membrane plasma membrane ABC-type xenobiotic transporter activity ABC-type xenobiotic transporter activity hormone transport cell surface efflux transmembrane transporter activity efflux transmembrane transporter activity membrane integral component of membrane apical plasma membrane apical plasma membrane ATPase activity ATPase activity transmembrane transporter activity brush border membrane ubiquitin protein ligase binding carbohydrate export maintenance of blood-brain barrier ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity xenobiotic transmembrane transporter activity xenobiotic transmembrane transporter activity daunorubicin transport apical part of cell phospholipid translocation phospholipid translocation phospholipid translocation intercellular canaliculus terpenoid transport carboxylic acid transmembrane transporter activity regulation of response to osmotic stress intestinal absorption transmembrane transport negative regulation of cell death establishment of blood-brain barrier transepithelial transport stem cell proliferation phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity phosphatidylethanolamine flippase activity phosphatidylethanolamine flippase activity ceramide floppase activity ceramide floppase activity ceramide floppase activity ceramide translocation ceramide translocation ceramide translocation export across plasma membrane export across plasma membrane floppase activity floppase activity positive regulation of anion channel activity protein localization to bicellular tight junction positive regulation of establishment of Sertoli cell barrier regulation of intestinal absorption carboxylic acid transmembrane transport xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic transport across blood-brain barrier xenobiotic transport across blood-brain barrier establishment of blood-retinal barrier positive regulation of response to drug regulation of chloride transport	02010 04976
TC0200002043.mm.2	Mcm8	minichromosome maintenance 8 homologous recombination repair factor	2	132816140	NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070	66634	19	nucleotide binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA binding chromatin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleoplasm chromosome cytosol DNA replication DNA replication initiation DNA repair cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle female gamete generation hydrolase activity enzyme binding MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding recombinational interstrand cross-link repair MCM complex male gamete generation protein stabilization protein localization to chromatin MCM8-MCM9 complex MCM8-MCM9 complex
TC0300002580.mm.2	Wdr3	WD repeat domain 3	3	-100138179	NM_175552, BC063100 NM_175552, BC063100	269470	20	nucleus nucleoplasm nucleolus maturation of SSU-rRNA snoRNA binding nuclear membrane small-subunit processome Pwp2p-containing subcomplex of 90S preribosome	03008
TC1300001374.mm.2	Net1	neuroepithelial cell transforming gene 1	13	-3882017, -3882017	NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699	56349	33	guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm plasma membrane small GTPase binding regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction intracellular signal transduction positive regulation of apoptotic process positive regulation of GTPase activity myoblast migration cellular response to hydrogen peroxide cellular response to ionizing radiation positive regulation of substrate adhesion-dependent cell spreading
TC1300000781.mm.2	Cdk20	cyclin-dependent kinase 20	13	64432552	NM_053180, BC031907 NM_053180, BC031907	105278	24	nucleotide binding neural tube closure protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytoplasm cilium protein phosphorylation cell cycle multicellular organism development kinase activity phosphorylation transferase activity floor plate formation embryonic camera-type eye development cell projection embryonic skeletal system development cell division roof of mouth development positive regulation of cardiac muscle cell proliferation protein localization to cilium protein threonine kinase activity regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning regulation of protein maturation embryonic brain development
TC1700001357.mm.2	Tfb1m	transcription factor B1, mitochondrial	17	-3519250	NM_146074, BC032930 NM_146074, BC032930	224481	26	rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity DNA binding RNA binding mitochondrion mitochondrial matrix rRNA processing transcription initiation from mitochondrial promoter methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation methylation mitochondrial transcription factor activity mitochondrial nucleoid
TC0100003877.mm.2	Poglut2	protein O-glucosyltransferase 2	1	-44106545	NM_023645, BC023141 NM_023645, BC023141	72050	23	nucleoplasm endoplasmic reticulum endoplasmic reticulum lumen cytosol endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity
TC1200000255.mm.2	Tmem18	transmembrane protein 18	12	30584442	NM_172049, BC024093 NM_172049, BC024093	211986	14	molecular_function DNA binding nucleus cytoplasm membrane integral component of membrane cell migration
TC0200002442.mm.2	Fam83d	family with sequence similarity 83, member D	2	158768098	NM_027975, BC068129 NM_027975, BC068129	71878	16	epithelial to mesenchymal transition cytoplasm spindle cytosol cytosol cytoskeleton cell cycle signal transduction microtubule binding cell population proliferation microtubule cytoskeleton cell migration kinesin binding protein kinase binding protein kinase binding regulation of TOR signaling regulation of TOR signaling regulation of protein catabolic process intercellular bridge cell division metaphase plate congression regulation of ERK1 and ERK2 cascade regulation of ERK1 and ERK2 cascade mitotic spindle mitotic spindle pole mitotic spindle pole protein localization to mitotic spindle protein localization to mitotic spindle positive regulation of cell cycle G1/S phase transition positive regulation of cell cycle G1/S phase transition
TC1200000825.mm.2	Ylpm1	YLP motif containing 1	12	84996320	NM_178363	56531	25	negative regulation of transcription by RNA polymerase II DNA-binding transcription repressor activity, RNA polymerase II-specific nucleus nucleus nucleus nucleoplasm cytosol nuclear speck regulation of telomere maintenance regulation of telomere maintenance
TC0400004151.mm.2	Atad3a	ATPase family, AAA domain containing 3A	4	-155740639	NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036	108888	43	nucleotide binding regulation of cell growth protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrion organization zinc ion binding membrane integral component of membrane mitochondrial nucleoid identical protein binding negative regulation of apoptotic process antiviral innate immune response
TC1400000501.mm.2	Cdkn3	cyclin-dependent kinase inhibitor 3	14	46760540	NM_028222, BC049694 NM_028222, BC049694	72391	17	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding cytoplasm cytosol cellular response to DNA damage stimulus cell cycle cell cycle arrest cell cycle arrest dephosphorylation hydrolase activity phosphatase activity perinuclear region of cytoplasm
TC0300002906.mm.2	Larp7	La ribonucleoprotein domain family, member 7	3	-127536713	NM_138593, BC153029 NM_138593, BC153029	28036	33	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II box C/D RNA 3'-end processing box C/D RNA 3'-end processing nucleic acid binding RNA binding nucleus nucleus nucleoplasm cytosol RNA processing mRNA processing spermatogenesis RNA splicing U6 snRNA binding U6 snRNA binding cell differentiation negative regulation of viral transcription negative regulation of chromatin binding germ cell proliferation regulation of mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome 7SK snRNA binding 7SK snRNP positive regulation of G1/S transition of mitotic cell cycle positive regulation of protein localization to Cajal body positive regulation of snRNA transcription by RNA polymerase II U6 2'-O-snRNA methylation U6 2'-O-snRNA methylation ribonucleoprotein complex
TC0500001066.mm.2	Cdc7	cell division cycle 7 (S. cerevisiae)	5	106964321, 106964560	NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702	12545	32	nucleotide binding double-strand break repair via break-induced replication protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm protein phosphorylation cell cycle positive regulation of cell population proliferation positive regulation of nuclear cell cycle DNA replication positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell cycle phase transition intercellular bridge metal ion binding cell division mitotic spindle	04110
TC0300000807.mm.2	S100a4	S100 calcium binding protein A4	3	90603769	NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100	20198	169	actin binding calcium ion binding calcium ion binding calcium ion binding protein binding nucleus nucleus identical protein binding identical protein binding neuron projection positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling metal ion binding transition metal ion binding calcium-dependent protein binding calcium-dependent protein binding perinuclear region of cytoplasm perinuclear region of cytoplasm RAGE receptor binding RAGE receptor binding
TC1700001805.mm.2	Glo1	glyoxalase 1	17	-30592861	NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432	109801	99	lactoylglutathione lyase activity lactoylglutathione lyase activity nucleoplasm cytosol plasma membrane carbohydrate metabolic process regulation of transcription by RNA polymerase II glutathione metabolic process zinc ion binding zinc ion binding methylglyoxal metabolic process lyase activity methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione osteoclast differentiation negative regulation of apoptotic process metal ion binding	00620
TC0500000852.mm.2	Mthfd2l	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	5	90931195	NM_026788	665563	17	histidine biosynthetic process catalytic activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity mitochondrion mitochondrial inner membrane mitochondrial matrix purine nucleotide biosynthetic process one-carbon metabolic process metabolic process cellular amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate metabolic process membrane oxidoreductase activity hydrolase activity tetrahydrofolate interconversion tetrahydrofolate interconversion	00670 01100
TC0100001548.mm.2	Tmco1	transmembrane and coiled-coil domains 1	1	167308669	NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098	68944	31	calcium channel activity calcium channel activity cytoplasm endoplasmic reticulum endoplasmic reticulum Golgi apparatus ion transport calcium ion transport cellular calcium ion homeostasis ER overload response membrane integral component of membrane integral component of endoplasmic reticulum membrane endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis calcium ion transmembrane transport calcium ion transmembrane transport
TC0200002579.mm.2	Ddx27	DEAD box helicase 27	2	167015312	NM_153065, BC011321 NM_153065, BC011321	228889	30	nucleotide binding nucleic acid binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus rRNA processing hydrolase activity ribosome biogenesis
TC1900000763.mm.2	Pdcd4	programmed cell death 4	19	53903350, 53892230	NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739	18569	88	RNA binding protein binding nucleus nucleus cytoplasm cytosol cytosol apoptotic process cell aging BMP signaling pathway positive regulation of smooth muscle cell apoptotic process negative regulation of apoptotic process negative regulation of transcription, DNA-templated positive regulation of inflammatory response regulation of protein metabolic process epithelial to mesenchymal transition involved in cardiac fibroblast development cellular response to lipopolysaccharide negative regulation of cytokine production involved in inflammatory response positive regulation of NIK/NF-kappaB signaling negative regulation of vascular associated smooth muscle cell proliferation negative regulation of myofibroblast differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of vascular associated smooth muscle cell apoptotic process positive regulation of endothelial cell apoptotic process
TC1000000744.mm.2	Lss	lanosterol synthase	10	76531604	NM_146006, BC029082 NM_146006, BC029082	16987	36	lanosterol synthase activity lanosterol synthase activity endoplasmic reticulum endoplasmic reticulum membrane lipid droplet lipid droplet lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process membrane sterol metabolic process isomerase activity intramolecular transferase activity regulation of protein stability intracellular membrane-bounded organelle	00100 01100
TC0600002656.mm.2	Arhgap25	Rho GTPase activating protein 25	6	-87458544, -87458544	NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752	232201	21	phagocytic cup phagocytic cup GTPase activator activity phagocytosis, engulfment phagocytosis, engulfment actin filament organization actin filament organization signal transduction negative regulation of small GTPase mediated signal transduction negative regulation of small GTPase mediated signal transduction activation of GTPase activity
TC1700002771.mm.2	Nme3	NME/NM23 nucleoside diphosphate kinase 3	17	24896499	NM_019730, BC028503, NME/NM23 NM_019730, BC028503, NME/NM23 NM_019730, BC028503, NME/NM23	79059	24	nucleotide binding nucleoside diphosphate kinase activity ATP binding mitochondrion GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process kinase activity phosphorylation transferase activity metal ion binding	00230 00240 01100
TC1900001510.mm.2	Arhgap19	Rho GTPase activating protein 19	19	-41766587	NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195	71085	22	GTPase activator activity cytoplasm plasma membrane signal transduction intracellular membrane-bounded organelle regulation of small GTPase mediated signal transduction
TC0X00000652.mm.2	Hmgb3	high mobility group box 3	X	71555916	NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037	15354	39	immune system process DNA binding RNA binding nucleus chromosome cytoplasm regulation of transcription by RNA polymerase II DNA binding, bending innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation
MG-1-neg-10339902_st
TC0500002458.mm.2	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	5	-62602445	NM_178407	212285	18	GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm signal transduction positive regulation of GTPase activity metal ion binding	04144
TC0200005331.mm.2					XR_140551
TC1800000344.mm.2	Wdr55	WD repeat domain 55	18	36760221	NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934	67936	17	molecular_function nucleus nucleoplasm nucleolus nucleolus cytoplasm rRNA processing rRNA processing
TC0100000267.mm.2	Lipt1	lipoyltransferase 1	1	37872218, 37872349, 37871737	NM_001037918, BC019519 NM_001037918, BC019519	623661	16	cytoplasm mitochondrion mitochondrion cellular protein modification process protein lipoylation transferase activity transferase activity, transferring acyl groups lipoyltransferase activity	00785 01100
TC0800000968.mm.2	Syce2	synaptonemal complex central element protein 2	8	84872110, 84872257	NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534	71846	31	synaptonemal complex central element central element protein binding nucleus nucleoplasm nucleoplasm chromosome cell cycle synaptonemal complex assembly cell division meiotic cell cycle
TC1200001832.mm.2	Fkbp3	FK506 binding protein 3	12	-65062431	NM_013902, BC002122, FK506 NM_013902, BC002122, FK506 NM_013902, BC002122, FK506	30795	31	peptidyl-prolyl cis-trans isomerase activity protein binding nucleus isomerase activity
TC0700004326.mm.2	Zfp764	zinc finger protein 764	7	-127403667	NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397	233893	16	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
TC1100002297.mm.2	Cep68	centrosomal protein 68	11	-20227036	NM_172260, BC027174 NM_172260, BC027174	216543	20	nucleoplasm cytoplasm centrosome cytosol cytoskeleton centrosome cycle centriole-centriole cohesion protein kinase binding protein domain specific binding cell junction protein localization to organelle centriolar satellite
TC0100000829.mm.2	Dgkd	diacylglycerol kinase, delta	1	87853286	NM_177646	227333	35	nucleotide binding NAD+ kinase activity diacylglycerol kinase activity diacylglycerol kinase activity diacylglycerol kinase activity ATP binding cytoplasm cytosol plasma membrane clathrin-coated pit phosphatidic acid biosynthetic process endocytosis signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway response to organic substance protein transport membrane kinase activity phosphorylation transferase activity kinase binding cytoplasmic vesicle intracellular signal transduction identical protein binding protein homodimerization activity positive regulation of epidermal growth factor receptor signaling pathway diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding protein heterodimerization activity negative regulation of protein kinase C signaling positive regulation of clathrin-dependent endocytosis	00561 00564 01100 04070
TC0400002613.mm.2	Alg2	asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)	4	-47469832	NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411	56737	22	alpha-1,3-mannosyltransferase activity alpha-1,3-mannosyltransferase activity GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity nucleus cytoplasm cytosol protein glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process actin cytoskeleton membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein glycosylation in endoplasmic reticulum protein glycosylation in endoplasmic reticulum protein heterodimerization activity protein N-terminus binding calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	00510 01100
TC1600000138.mm.2	Snx29	sorting nexin 29	16	11322903, 11405647	NM_028964	74478	15	molecular_function biological_process phosphatidylinositol binding
TC1300001642.mm.2	H3c3	H3 clustered histone 3	13	-23745041	NM_175653, BC120800, BC120802 NM_175653, BC120800, BC120802 NM_175653, BC120800, BC120802	319148	7	nucleosome nucleus nucleoplasm nucleosome assembly	05322
TC1400000910.mm.2	Pinx1	PIN2/TERF1 interacting, telomerase inhibitor 1	14	63860311	NM_028228, BC115636 NM_028228, BC115636	72400	17	nuclear chromosome chromosome, centromeric region kinetochore chromosome, telomeric region nucleic acid binding nucleus nucleoplasm chromosome nucleolus mitochondrion spindle telomere maintenance via telomerase mitotic metaphase plate congression telomerase inhibitor activity negative regulation of G2/M transition of mitotic cell cycle negative regulation of protein ubiquitination regulation of protein stability negative regulation of telomere maintenance via telomerase protein-containing complex binding negative regulation of telomerase activity telomerase RNA binding protein localization to chromosome, telomeric region protein localization to nucleolus positive regulation of telomeric DNA binding positive regulation of protein localization to nucleolus
TC1100003410.mm.2	Aatf	apoptosis antagonizing transcription factor	11	-84422855	NM_019816, BC025080 NM_019816, BC025080	56321	42	protein binding nucleus nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm Golgi apparatus cytosol regulation of transcription by RNA polymerase II cell adhesion regulation of mitotic cell cycle protein kinase binding negative regulation of superoxide anion generation embryonic cleavage ribosome biogenesis negative regulation of amyloid precursor protein biosynthetic process negative regulation of apoptotic process leucine zipper domain binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II tau protein binding negative regulation of reactive oxygen species metabolic process negative regulation of apoptotic signaling pathway
MG-1-pos-10338128_st
TC0100002899.mm.2	Kdsr	3-ketodihydrosphingosine reductase	1	-106720409, -106731201	NM_027534, BC023820 NM_027534, BC023820	70750	23	endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process sphingolipid metabolic process 3-keto-sphinganine metabolic process 3-keto-sphinganine metabolic process membrane integral component of membrane oxidoreductase activity sphingolipid biosynthetic process sphingolipid biosynthetic process 3-dehydrosphinganine reductase activity 3-dehydrosphinganine reductase activity	00600 01100
TC0700002924.mm.2					XR_105097
TC0600002917.mm.2	Camk1	calcium/calmodulin-dependent protein kinase I	6	-113334123	NM_133926, BC014825 NM_133926, BC014825	52163	49	nucleotide binding catalytic activity protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calmodulin-dependent protein kinase activity protein binding calmodulin binding ATP binding intracellular anatomical structure nucleus cytoplasm protein phosphorylation protein phosphorylation protein phosphorylation nucleocytoplasmic transport nucleocytoplasmic transport cell cycle signal transduction multicellular organism development nervous system development metabolic process positive regulation of neuron projection development postsynaptic density kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell differentiation negative regulation of protein binding regulation of protein localization positive regulation of peptidyl-serine phosphorylation regulation of protein binding positive regulation of transcription by RNA polymerase II positive regulation of protein export from nucleus positive regulation of protein export from nucleus regulation of synapse organization regulation of muscle cell differentiation positive regulation of muscle cell differentiation positive regulation of synapse structural plasticity positive regulation of syncytium formation by plasma membrane fusion positive regulation of dendritic spine development positive regulation of protein serine/threonine kinase activity glutamatergic synapse positive regulation of protein acetylation
TC1600001050.mm.2	Chaf1b	chromatin assembly factor 1, subunit B (p60)	16	93883900	NM_028083, BC013532 NM_028083, BC013532	110749	29	chromatin protein binding nucleus nucleoplasm cytoplasm DNA replication DNA repair nucleosome assembly DNA replication-dependent nucleosome assembly cellular response to DNA damage stimulus cell cycle chromatin assembly protein-containing complex CAF-1 complex CAF-1 complex
TC0X00002648.mm.2	Maged1	MAGE family member D1	X	-94535473	NM_019791, BC016438, BC031461 NM_019791, BC016438, BC031461 NM_019791, BC016438, BC031461	94275	69	chromatin transcription coactivator activity protein binding nucleus cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II membrane circadian regulation of gene expression protein-containing complex regulation of circadian rhythm identical protein binding regulation of apoptotic process positive regulation of MAP kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated rhythmic process negative regulation of epithelial cell proliferation positive regulation of branching involved in ureteric bud morphogenesis positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway	04722
TC0200002157.mm.2	Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	2	145242610, 145167774	NM_053195, BC017615 NM_053195, BC017615	94249	13	calcium channel activity plasma membrane plasma membrane integral component of plasma membrane ion transport cation transport potassium ion transport sodium ion transport calcium ion transport cellular calcium ion homeostasis cellular calcium ion homeostasis cellular calcium ion homeostasis cellular calcium ion homeostasis calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity positive regulation of gene expression negative regulation of gene expression symporter activity antiporter activity membrane integral component of membrane bone mineralization sodium ion transmembrane transport transmembrane transport calcium ion transmembrane transport calcium ion transmembrane transport potassium ion transmembrane transport cell periphery cell periphery
TC1200002002.mm.2	Erh	ERH mRNA splicing and mitosis factor	12	-80634020	NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423	13877	34	osteoblast differentiation nucleus methyl-CpG binding membrane midbody methylosome
MG-1-neg-10343507_st
TC0400002709.mm.2	Tmem245	transmembrane protein 245	4	-56876013, -56876012	NM_175518	242474	16	membrane integral component of membrane
TC1400001152.mm.2	Bora	bora, aurora kinase A activator	14	99046376	NM_175265, BC052183 NM_175265, BC052183	77744	19	nucleus cytoplasm cell cycle regulation of mitotic nuclear division regulation of mitotic nuclear division protein kinase binding protein kinase binding activation of protein kinase activity regulation of protein localization cell division regulation of mitotic spindle organization regulation of mitotic spindle organization meiotic spindle
TC0400001477.mm.2	Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	4	127021300, 127021300	NM_023603, NR_045010, BC089305 NM_023603, NR_045010, BC089305 NM_023603, NR_045010, BC089305	71514	84	negative regulation of transcription by RNA polymerase II alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome double-strand break repair via homologous recombination chromatin transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding activation of innate immune response immune system process nucleic acid binding DNA binding chromatin binding RNA binding protein binding nucleus nucleus nucleoplasm cytoplasm DNA repair regulation of transcription, DNA-templated mRNA processing cellular response to DNA damage stimulus RNA splicing nuclear matrix paraspeckles paraspeckles regulation of circadian rhythm negative regulation of circadian rhythm protein homodimerization activity histone deacetylase binding innate immune response positive regulation of sister chromatid cohesion negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II rhythmic process chromosome organization regulation of cell cycle histone H3 deacetylation RNA polymerase II transcription regulator complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
TC0200000391.mm.2	Zmynd19	zinc finger, MYND domain containing 19	2	24949776, 24950157	NM_026021, BC027321 NM_026021, BC027321	67187	26	molecular_function cytoplasm plasma membrane biological_process membrane synapse metal ion binding
TC1100004000.mm.2	Abca9	ATP-binding cassette, sub-family A (ABC1), member 9	11	-110100821	NM_147220	217262	15	nucleotide binding lipid transporter activity ATP binding mitochondrion lipid transport membrane integral component of membrane ATPase activity ATPase-coupled transmembrane transporter activity intracellular membrane-bounded organelle	02010
TC0X00002269.mm.2	Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	X	-57231484, -57231484	NM_152801, BC156697 NM_152801, BC156697	73341	35	guanyl-nucleotide exchange factor activity protein binding cell-cell junction lamellipodium lamellipodium assembly regulation of Rho protein signal transduction intracellular signal transduction cell projection	04810 05212
TC1900000814.mm.2	Trub1	TruB pseudouridine (psi) synthase family member 1	19	57452905, 57452905	NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592	72133	18	pseudouridine synthesis RNA binding nucleus cytoplasm mitochondrion cytosol RNA processing tRNA modification RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity mRNA pseudouridine synthesis mRNA pseudouridine synthesis
TC0200001741.mm.2	Bub1b	BUB1B, mitotic checkpoint serine/threonine kinase	2	118598210	NM_009773, BC031577 NM_009773, BC031577	12236	96	nucleotide binding chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus chromosome cytoplasm spindle cytosol protein phosphorylation apoptotic process cell cycle metaphase/anaphase transition of mitotic cell cycle mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity perinuclear region of cytoplasm cell division meiotic sister chromatid cohesion, centromeric protein localization to chromosome, centromeric region	04110
TC0200004725.mm.2	Tasp1	taspase, threonine aspartase 1	2	-139833478, -139976218	NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597	75812	25	threonine-type endopeptidase activity threonine-type endopeptidase activity cytoplasm proteolysis peptidase activity hydrolase activity identical protein binding positive regulation of transcription, DNA-templated protein maturation
TC1100004301.mm.2	Trim47	tripartite motif-containing 47	11	-116105749	NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059	217333	23	ubiquitin-protein transferase activity ubiquitin-protein transferase activity nucleus cytoplasm cytosol zinc ion binding protein ubiquitination protein ubiquitination transferase activity metal ion binding
TC0600003003.mm.2	Ankrd26	ankyrin repeat domain 26	6	-118501299	NM_001081112	232339	22	protein binding cytoplasm centrosome actin cytoskeleton regulation of lipid metabolic process regulation of fatty acid metabolic process negative regulation of multicellular organism growth glucose homeostasis negative regulation of fat cell differentiation negative regulation of organ growth negative regulation of insulin receptor signaling pathway regulation of feeding behavior negative regulation of ERK1 and ERK2 cascade
TC0X00002689.mm.2	Ophn1	oligophrenin 1	X	-98554279, -98873725	NM_052976, BC004845 NM_052976, BC004845	94190	39	actin binding GTPase activator activity GTPase activator activity protein binding phospholipid binding cytoplasm cytoplasm endocytosis signal transduction nervous system development actin cytoskeleton actin cytoskeleton cerebellar granule cell differentiation cerebral cortex neuron differentiation actin cytoskeleton organization actin cytoskeleton organization cell junction regulation of endocytosis regulation of endocytosis neuron differentiation dendrite neuron projection development cell junction assembly regulation of Rho protein signal transduction ionotropic glutamate receptor binding cell projection terminal bouton terminal bouton dendritic spine dendritic spine establishment of epithelial cell apical/basal polarity synapse synaptic vesicle endocytosis synaptic vesicle endocytosis synaptic vesicle endocytosis cell morphogenesis involved in neuron differentiation regulation of synaptic transmission, glutamatergic regulation of synaptic transmission, glutamatergic maintenance of postsynaptic specialization structure glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization negative regulation of proteasomal protein catabolic process negative regulation of proteasomal protein catabolic process
TC1800000019.mm.2	Svil	supervillin	18	5046588, 5046588	NM_153153	225115	32	actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm cytosol cytoskeleton plasma membrane cytoskeleton organization skeletal muscle tissue development actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton membrane cell junction cell projection costamere actin filament severing actin filament binding actin filament binding barbed-end actin filament capping
TC0100001303.mm.2	Aspm	abnormal spindle microtubule assembly	1	139454772	NM_009791	12316	49	spindle pole neuron migration neuron migration positive regulation of neuroblast proliferation positive regulation of neuroblast proliferation calmodulin binding nucleus cytoplasm centrosome cytoskeleton microtubule cell cycle spindle organization spermatogenesis brain development male gonad development apical plasma membrane forebrain neuroblast division cerebral cortex development midbody midbody microtubule minus-end negative regulation of neuron differentiation negative regulation of asymmetric cell division oogenesis developmental growth cell division regulation of meiotic cell cycle spindle localization maintenance of centrosome location meiotic spindle positive regulation of canonical Wnt signaling pathway spindle assembly involved in meiosis neuronal stem cell population maintenance mitotic spindle pole mitotic spindle pole
TC0200003401.mm.2	Strbp	spermatid perinuclear RNA binding protein	2	-37569867, -37569867, -37569867, -37569867	NM_009261, BC014710 NM_009261, BC014710	20744	32	manchette RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding nucleus cytoplasm cytoskeleton movement of cell or subcellular component multicellular organism development spermatogenesis spermatid development mechanosensory behavior microtubule binding microtubule cytoskeleton tubulin binding cell differentiation
TC1300001205.mm.2	Depdc1b	DEP domain containing 1B	13	108316336	NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331	218581	16	molecular_function GTPase activator activity signal transduction cell migration positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway intracellular signal transduction
TC0500000307.mm.2					NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788			nucleotide binding UTP binding catalytic activity aspartate carbamoyltransferase activity aspartate carbamoyltransferase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity dihydroorotase activity dihydroorotase activity protein kinase activity ATP binding nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol 'de novo' pyrimidine nucleobase biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UTP biosynthetic process UTP biosynthetic process cellular amino acid metabolic process glutamine metabolic process glutamine metabolic process nitrogen compound metabolic process metabolic process zinc ion binding nuclear matrix amino acid binding transferase activity carboxyl- or carbamoyltransferase activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ligase activity drug metabolic process peptidyl-threonine phosphorylation citrulline biosynthetic process citrulline biosynthetic process enzyme binding response to insulin protein-containing complex response to starvation identical protein binding cell projection neuronal cell body terminal bouton protein autophosphorylation metal ion binding
TC1200000675.mm.2	Mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase	12	76255231	NM_138745, BC008523 NM_138745, BC008523	108156	53	histidine biosynthetic process nucleotide binding neutrophil homeostasis neural tube closure catalytic activity formate-tetrahydrofolate ligase activity formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity ATP binding cytoplasm mitochondrion cytosol cytosol purine nucleotide biosynthetic process methionine metabolic process one-carbon metabolic process heart development metabolic process cellular amino acid biosynthetic process serine family amino acid metabolic process serine family amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate biosynthetic process 10-formyltetrahydrofolate biosynthetic process oxidoreductase activity hydrolase activity ligase activity transsulfuration tetrahydrofolate interconversion tetrahydrofolate interconversion tetrahydrofolate interconversion somite development	00670 01100
TC1300001419.mm.2	Gtpbp4	GTP binding protein 4	13	-8972477	NM_027000, BC025431 NM_027000, BC025431	69237	30	regulation of cyclin-dependent protein serine/threonine kinase activity nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus nucleoplasm nucleolus cytoplasm cytosol negative regulation of DNA replication negative regulation of cell population proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination nuclear membrane negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization	03008
TC1100003345.mm.2	Myo1d	myosin ID	11	-80482126	NM_177390, BC150765 NM_177390, BC150765	338367	34	microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding protein binding calmodulin binding ATP binding cytoplasm endosome smooth endoplasmic reticulum plasma membrane microvillus brush border brush border actin filament organization negative regulation of phosphatase activity protein transport actin cytoskeleton membrane basolateral plasma membrane myosin complex protein domain specific binding vesicle transport along actin filament axon axolemma actin-dependent ATPase activity actin-dependent ATPase activity cytoplasmic vesicle vesicle cell projection neuron projection neuronal cell body neuronal cell body myelin sheath myelin sheath myelin sheath plasma membrane raft calcium-dependent protein binding actin filament binding actin filament binding cellular localization apical dendrite
TC1400002863.mm.2	Ipo4	importin 4	14	-55625399	NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150	75751	25	chromatin protein binding nucleus cytoplasm DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein import into nucleus protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding protein-containing complex ribosome biogenesis nuclear import signal receptor activity
TC0900000581.mm.2	Nxpe4	neurexophilin and PC-esterase domain family, member 4	9	48362040	NM_172921, BC085195, BC094249 NM_172921, BC085195, BC094249 NM_172921, BC085195, BC094249	244853	13	molecular_function extracellular region biological_process
TC0400001215.mm.2	Stil	Scl/Tal1 interrupting locus	4	115000117	NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493	20460	29	embryonic axis specification in utero embryonic development neural tube closure heart looping protein binding cytoplasm centrosome centrosome centriole centriole cytoskeleton mitotic spindle organization mitotic spindle organization smoothened signaling pathway smoothened signaling pathway multicellular organism development determination of left/right symmetry neural tube development forebrain development notochord development floor plate development multicellular organism growth identical protein binding negative regulation of apoptotic process positive regulation of cyclin-dependent protein serine/threonine kinase activity regulation of centriole replication centrosome duplication centrosome duplication centrosome duplication mitotic spindle checkpoint protein localization to centrosome protein localization to centrosome non-motile cilium assembly
TC0300000354.mm.2	Noct	nocturnin	3	51224446	NM_009834, BC139369, BC139370 NM_009834, BC139369, BC139370 NM_009834, BC139369, BC139370	12457	48	3'-5'-exoribonuclease activity deadenylation-dependent decapping of nuclear-transcribed mRNA P-body RNA binding mRNA binding poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus cytoplasm mitochondrion NADP metabolic process circadian rhythm circadian rhythm response to extracellular stimulus negative regulation of gene expression hydrolase activity NADP phosphatase activity response to lipopolysaccharide circadian regulation of gene expression P-body assembly regulation of circadian rhythm positive regulation of fat cell differentiation negative regulation of osteoblast differentiation regulation of embryonic development metal ion binding mRNA stabilization perinuclear region of cytoplasm rhythmic process NADPH phosphatase activity
TC0100001699.mm.2	Sccpdh	saccharopine dehydrogenase (putative)	1	179668230	NM_178653, BC025803 NM_178653, BC025803	109232	18	molecular_function mitochondrion mitochondrion lipid droplet lipid droplet plasma membrane glycolipid biosynthetic process oxidoreductase activity midbody
MG-1-pos-10341135_st
TC0800001533.mm.2	Rab4a	RAB4A, member RAS oncogene family	8	123805995	NM_009003, BC138508 NM_009003, BC138508	19341	35	nucleotide binding ATPase activator activity GTPase activity protein binding GTP binding cytoplasm endosome endosome cytosol plasma membrane small GTPase mediated signal transduction protein transport membrane GDP binding antigen processing and presentation syntaxin binding regulation of endocytosis regulation of endocytosis cytoplasmic vesicle membrane vesicle Rab protein signal transduction insulin-responsive compartment insulin-responsive compartment ionotropic glutamate receptor binding intracellular membrane-bounded organelle perinuclear region of cytoplasm ATPase binding recycling endosome extracellular exosome postsynaptic recycling endosome postsynaptic recycling endosome anchored component of synaptic vesicle membrane	04144
TC0400000133.mm.2	Tmem64	transmembrane protein 64	4	15265819	NM_181401, BC030341 NM_181401, BC030341	100201	20	protein binding endoplasmic reticulum membrane integral component of membrane regulation of ATPase activity positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of bone resorption regulation of cytosolic calcium ion concentration negative regulation of canonical Wnt signaling pathway
TC0400001743.mm.2	Akr7a5	aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)	4	139310743	NM_025337, BC031857 NM_025337, BC031857	110198	25	alditol:NADP+ 1-oxidoreductase activity nuclear envelope cytoplasm mitochondrion Golgi apparatus cytosol oxidoreductase activity phenanthrene-9,10-epoxide hydrolase activity daunorubicin metabolic process doxorubicin metabolic process
TC1000003023.mm.2	Hmga2	high mobility group AT-hook 2	10	-120361267	NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085	15364	139	negative regulation of transcription by RNA polymerase II nuclear chromosome chromatin DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding minor groove of adenine-thymine-rich DNA binding transcription coregulator activity protein binding nucleus nucleus nucleus regulation of transcription, DNA-templated cell cycle signal transduction spermatogenesis positive regulation of cell population proliferation male gonad development regulation of cell cycle process positive regulation of gene expression enzyme binding cell proliferation in forebrain pituitary gland development negative regulation of Wnt signaling pathway chromosome condensation adrenal gland development negative regulation of intracellular steroid hormone receptor signaling pathway somatic stem cell population maintenance somatic stem cell population maintenance regulation of growth positive regulation of multicellular organism growth positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II negative regulation of receptor signaling pathway via JAK-STAT negative regulation of astrocyte differentiation positive regulation of DNA-binding transcription factor activity cell division meiotic cell cycle regulation of growth hormone secretion lung epithelium development epithelial tube branching involved in lung morphogenesis positive regulation of epithelial cell proliferation involved in lung morphogenesis adipose tissue development fat pad development positive regulation of cell proliferation in bone marrow regulation of peptide hormone secretion positive regulation of stem cell proliferation negative regulation of cellular senescence
TC1400002341.mm.2	Polr3d	polymerase (RNA) III (DNA directed) polypeptide D	14	-70438747, -70438747	NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102	67065	19	immune system process DNA binding chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytosol transcription by RNA polymerase III positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus	00230 00240 01100 03020 04623
TC1500001347.mm.2	Rida	reactive intermediate imine deaminase A homolog	15	-34484021	NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592	15473	17	RNA binding mRNA binding nucleus cytoplasm mitochondrion mitochondrion mitochondrial matrix peroxisome cytosol cytosol mRNA catabolic process hydrolase activity endoribonuclease activity, producing 3'-phosphomonoesters negative regulation of translation deaminase activity deaminase activity long-chain fatty acid binding identical protein binding ion binding transition metal ion binding negative regulation of epithelial cell proliferation mRNA destabilization organonitrogen compound catabolic process organonitrogen compound catabolic process
TC1300000045.mm.2	Idi1	isopentenyl-diphosphate delta isomerase	13	8885605	NM_145360, BC004801, BC110313 NM_145360, BC004801, BC110313 NM_145360, BC004801, BC110313	319554	26	magnesium ion binding isopentenyl-diphosphate delta-isomerase activity isopentenyl-diphosphate delta-isomerase activity cytoplasm mitochondrion peroxisome isoprenoid biosynthetic process isopentenyl diphosphate biosynthetic process manganese ion binding response to stilbenoid	00900 01100
TC0100001271.mm.2	Kif14	kinesin family member 14	1	136467847	NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258	381293	25	nucleotide binding regulation of cell growth microtubule motor activity ATP binding nucleus cytoplasm cytosol cytoskeleton kinesin complex microtubule microtubule plasma membrane microtubule-based movement mitotic metaphase plate congression microtubule binding microtubule binding positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed regulation of G2/M transition of mitotic cell cycle tubulin binding ATPase activity ATPase activity protein kinase binding cerebellar granular layer structural organization cerebellar Purkinje cell layer structural organization cerebellar cortex development hippocampus development olfactory bulb development cell proliferation in forebrain cerebral cortex development regulation of cell adhesion PDZ domain binding regulation of cell migration midbody SCF-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of myelination activation of protein kinase activity positive regulation of cytokinesis regulation of Rap protein signal transduction negative regulation of integrin activation substrate adhesion-dependent cell spreading negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of neuron apoptotic process negative regulation of neuron apoptotic process establishment of protein localization spindle midzone cell division Flemming body regulation of cell maturation regulation of G1/S transition of mitotic cell cycle
TC0900000639.mm.2	Poglut3	protein O-glucosyltransferase 3	9	53384022	NM_212445	68304	16	endoplasmic reticulum endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity
TC1200001306.mm.2	Ncapg2	non-SMC condensin II complex, subunit G2	12	116405435	NM_133762, BC076631 NM_133762, BC076631	76044	27	mitotic sister chromatid segregation condensin complex condensin complex condensin complex inner cell mass cell proliferation protein binding nucleus nucleus nucleoplasm transcription by RNA polymerase II transcription by RNA polymerase II cell cycle nuclear speck erythrocyte differentiation erythrocyte differentiation chromosome condensation methylated histone binding bHLH transcription factor binding cell division transcription regulator inhibitor activity
TC0100002413.mm.2	Raph1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	1	-60483184	NM_001045513	77300	23	protein binding cytosol cytosol plasma membrane plasma membrane nuclear body cell leading edge axon extension
TC0100000526.mm.2	Fastkd2	FAST kinase domains 2	1	63730624	NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813	75619	19	RNA binding protein kinase activity mitochondrion mitochondrion mitochondrial inner membrane rRNA binding ribonucleoprotein granule ribosome biogenesis mitochondrial nucleoid positive regulation of mitochondrial translation apoptotic process in response to mitochondrial fragmentation mitochondrial large ribosomal subunit assembly
TC1100000544.mm.2	Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	11	50377677, 50378290, 50377796, 50378235, 50376989	NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224	59013	52	nucleic acid binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm spliceosomal complex cytosol mRNA processing RNA splicing identical protein binding regulation of RNA splicing regulation of RNA splicing catalytic step 2 spliceosome cellular response to interleukin-7 ribonucleoprotein complex
TC1300001560.mm.2	H1f5	H1.5 linker histone, cluster member	13	-21779831	NM_020034, BC146469 NM_020034, BC146469	56702	34	nucleosome DNA binding double-stranded DNA binding protein binding nucleus chromosome nucleosome assembly muscle organ development nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing negative regulation of DNA recombination
TC1600001124.mm.2	Adcy9	adenylate cyclase 9	16	-4284885	NM_009624, BC166017 NM_009624, BC166017	11515	44	nucleotide binding in utero embryonic development adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane integral component of plasma membrane integral component of plasma membrane cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway cyclic nucleotide biosynthetic process membrane integral component of membrane lyase activity phosphorus-oxygen lyase activity axon dendrite intracellular signal transduction metal ion binding adenylate cyclase-activating adrenergic receptor signaling pathway	00230 04020 04062 04114 04270 04540 04912 04914 04916 04962 04970 04971 04972 04976 05414
TC0X00000454.mm.2	Stk26	serine/threonine kinase 26	X	50841370	NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193	70415	20	Golgi membrane nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus Golgi-associated vesicle cytosol protein phosphorylation apoptotic process cellular response to starvation membrane kinase activity phosphorylation apical plasma membrane transferase activity microvillus assembly negative regulation of cell migration response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process protein autophosphorylation metal ion binding perinuclear region of cytoplasm cell periphery regulation of hydrogen peroxide-induced cell death
TC0200000354.mm.2	Pdss1	prenyl (solanesyl) diphosphate synthase, subunit 1	2	22895521, 22895521	NM_019501, BC026820 NM_019501, BC026820	56075	18	trans-hexaprenyltranstransferase activity trans-hexaprenyltranstransferase activity prenyltransferase activity protein binding mitochondrion ubiquinone biosynthetic process ubiquinone biosynthetic process ubiquinone biosynthetic process isoprenoid biosynthetic process isoprenoid biosynthetic process isoprenoid biosynthetic process transferase activity metal ion binding protein heterodimerization activity trans-octaprenyltranstransferase activity all-trans-decaprenyl-diphosphate synthase activity transferase complex transferase complex transferase complex	00900
TC1900000758.mm.2	Smc3	structural maintenance of chromosomes 3	19	53600395	NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935	13006	75	nucleotide binding chromosome, centromeric region chromatin lateral element chromatin binding protein binding ATP binding basement membrane nucleus nucleoplasm nucleoplasm chromosome regulation of DNA replication DNA repair cellular response to DNA damage stimulus cell cycle sister chromatid cohesion cohesin complex cohesin complex nuclear matrix stem cell population maintenance meiotic cohesin complex meiotic cohesin complex nuclear meiotic cohesin complex mediator complex binding protein heterodimerization activity beta-tubulin binding chromosome organization cell division meiotic cell cycle meiotic cell cycle dynein complex binding mitotic spindle assembly mitotic spindle pole	04110 04114
TC1500002037.mm.2	Hdac10	histone deacetylase 10	15	-89123302	NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018	170787	24	histone deacetylase complex negative regulation of transcription by RNA polymerase II histone deacetylase activity nucleus nucleoplasm cytoplasm DNA repair DNA recombination regulation of transcription, DNA-templated autophagy cellular response to DNA damage stimulus macroautophagy histone deacetylation hydrolase activity deacetylase activity enzyme binding positive regulation of mismatch repair peptidyl-lysine deacetylation homologous recombination histone deacetylase binding negative regulation of transcription, DNA-templated metal ion binding acetylputrescine deacetylase activity acetylspermidine deacetylase activity polyamine deacetylation spermidine deacetylation
TC0200004440.mm.2	Oip5	Opa interacting protein 5	2	-119609531	NM_001042653, BC115883, BC116660 NM_001042653, BC115883, BC116660 NM_001042653, BC115883, BC116660	70645	14	chromosome, centromeric region chromatin chromatin nucleus nucleus nucleus chromosome cell cycle chromosome segregation chromocenter Cajal body nuclear speck CENP-A containing nucleosome assembly identical protein binding intracellular membrane-bounded organelle metal ion binding cell division
TC0X00003175.mm.2	Tsr2	TSR2 20S rRNA accumulation	X	-151087093	NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668	69499	16	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) molecular_function rRNA processing
TC0800002236.mm.2	Spcs3	signal peptidase complex subunit 3 homolog (S. cerevisiae)	8	-54520432	NM_029701, BC054817 NM_029701, BC054817	76687	18	endoplasmic reticulum signal peptidase complex signal peptide processing proteolysis peptidase activity membrane integral component of membrane hydrolase activity viral protein processing intracellular membrane-bounded organelle protein targeting to ER	03060
TC0500000434.mm.2	Lyar	Ly1 antibody reactive clone	5	38220481	NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927	17089	30	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II photoreceptor outer segment immune system process DNA binding DNA binding nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm rRNA processing rRNA processing activating transcription factor binding identical protein binding cell projection innate immune response negative regulation of innate immune response positive regulation of transcription by RNA polymerase I metal ion binding erythrocyte development positive regulation of phagocytosis transcription regulator inhibitor activity
TC0700002057.mm.2	Ap2a2	adaptor-related protein complex 2, alpha 2 subunit	7	141562179	NM_007459, BC058099 NM_007459, BC058099	11772	78	protein binding plasma membrane clathrin-coated pit intracellular protein transport endocytosis receptor-mediated endocytosis synaptic vesicle lipid binding protein transport membrane vesicle-mediated transport kinase binding protein kinase binding protein domain specific binding membrane coat AP-2 adaptor complex AP-2 adaptor complex AP-2 adaptor complex clathrin adaptor complex secretory granule cytoplasmic vesicle phosphatidylinositol binding clathrin adaptor activity protein-containing complex binding clathrin-dependent endocytosis clathrin-dependent endocytosis clathrin-dependent endocytosis disordered domain specific binding cargo adaptor activity regulation of hematopoietic stem cell differentiation	04144 05016
TC0200003697.mm.2	Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	2	-69193894	NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605	66442	23	chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cytosol cell cycle mitotic spindle organization chromosome segregation chromosome segregation Ndc80 complex Ndc80 complex cell division
TC1500000392.mm.2	Deptor	DEP domain containing MTOR-interacting protein	15	55112316, 55133435	NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690	97998	42	negative regulation of protein kinase activity negative regulation of TOR signaling intracellular signal transduction negative regulation of cell size regulation of extrinsic apoptotic signaling pathway
TC0600000962.mm.2	Smyd5	SET and MYND domain containing 5	6	85431975	NM_144918, BC016525 NM_144918, BC016525	232187	22	molecular_function cellular_component biological_process methyltransferase activity transferase activity methylation metal ion binding
TC0900001461.mm.2	Ngp	neutrophilic granule protein	9	110419807	NM_008694, BC119403, BC119405 NM_008694, BC119403, BC119405 NM_008694, BC119403, BC119405	18054	22	cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space defense response negative regulation of peptidase activity negative regulation of angiogenesis peptidase inhibitor activity cytoplasmic vesicle negative regulation of lymphangiogenesis
TC0500001251.mm.2	Pop5	processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)	5	115235850	NM_026398, BC022670 NM_026398, BC022670	117109	19	ribonuclease MRP activity ribonuclease MRP complex ribonuclease MRP complex ribonuclease MRP complex tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolar ribonuclease P complex nucleolus rRNA processing rRNA processing tRNA processing tRNA processing RNA metabolic process hydrolase activity multimeric ribonuclease P complex ribonuclease P RNA binding	03008 03013
TC1100003318.mm.2	Wsb1	WD repeat and SOCS box-containing 1	11	-79239381, -79239382	NM_001042565, NM_019653, BC053391 NM_001042565, NM_019653, BC053391 NM_001042565, NM_019653, BC053391	78889	31	biological_process intracellular signal transduction
TC0600001998.mm.2	Tmem209	transmembrane protein 209	6	-30481232, -30481038	NM_178625, BC052187, BC057109 NM_178625, BC052187, BC057109 NM_178625, BC052187, BC057109	72649	15	molecular_function cellular_component biological_process membrane integral component of membrane
TC1700001138.mm.2	Wdr43	WD repeat domain 43	17	71616214	NM_175639	72515	22	chromatin RNA polymerase II complex binding fibrillar center transcription elongation regulator activity RNA binding protein binding nucleus nucleoplasm nucleolus nucleolus rRNA processing regulation of transcription elongation from RNA polymerase II promoter ribosome biogenesis positive regulation of transcription by RNA polymerase I regulation of stem cell population maintenance positive regulation of rRNA processing	03008
TC1600001378.mm.2	Tra2b	transformer 2 beta	16	-22244551	NM_009186, BC061177, BC086795 NM_009186, BC061177, BC086795 NM_009186, BC061177, BC086795	20462	54	regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding protein binding nucleus nucleus nuclear inner membrane nucleoplasm spliceosomal complex spliceosomal complex mRNA processing RNA splicing protein domain specific binding cerebral cortex regionalization protein-containing complex pre-mRNA binding pre-mRNA binding identical protein binding regulation of RNA splicing negative regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome perinuclear region of cytoplasm poly-purine tract binding cellular response to glucose stimulus embryonic brain development	03040
TC0400002527.mm.2	Arhgef39	Rho guanine nucleotide exchange factor (GEF) 39	4	-43496143	NM_001013377, BC080700 NM_001013377, BC080700	230098	13	guanyl-nucleotide exchange factor activity plasma membrane plasma membrane membrane positive regulation of cell migration positive regulation of cell migration regulation of Rho protein signal transduction
TC0600001254.mm.2	Fancd2	Fanconi anemia, complementation group D2	6	113531681, 113531681	NM_001033244, BC139004 NM_001033244, BC139004	211651	85	condensed chromosome condensed chromosome protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytosol DNA repair cellular response to DNA damage stimulus cell cycle homologous chromosome pairing at meiosis homologous chromosome pairing at meiosis multicellular organism development gamete generation response to gamma radiation nuclear body intra-S DNA damage checkpoint cellular response to oxidative stress interstrand cross-link repair regulation of regulatory T cell differentiation brain morphogenesis regulation of inflammatory response regulation of DNA-binding transcription factor activity DNA polymerase binding DNA polymerase binding neuronal stem cell population maintenance double-strand break repair involved in meiotic recombination regulation of CD40 signaling pathway
TC0400004186.mm.2	Nfia	nuclear factor I/A	4	97581942, 97777625	NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878	18027	121	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding chromatin binding DNA-binding transcription factor activity intracellular anatomical structure nucleus nucleus nucleus nucleoplasm DNA replication regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription factor binding cell junction positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II synapse maturation ureter development
TC1700000819.mm.2	Mmut	methylmalonyl-Coenzyme A mutase	17	40934684	NM_008650, BC019175 NM_008650, BC019175	17850	42	catalytic activity GTPase activity methylmalonyl-CoA mutase activity methylmalonyl-CoA mutase activity methylmalonyl-CoA mutase activity cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial matrix post-embryonic development isomerase activity intramolecular transferase activity cobalamin binding identical protein binding protein homodimerization activity positive regulation of GTPase activity metal ion binding homocysteine metabolic process modified amino acid binding	00280 00630 00640 01100
TC0X00001371.mm.2	Rnf128	ring finger protein 128	X	139610619, 139563339	NM_001254761, NM_023270, BC010477 NM_001254761, NM_023270, BC010477 NM_001254761, NM_023270, BC010477	66889	49	negative regulation of cytokine production cytoplasm late endosome late endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus cytoskeleton ubiquitin-dependent protein catabolic process membrane integral component of membrane transferase activity regulation of protein stability metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity
TC1000001282.mm.2	E2f7	E2F transcription factor 7	10	110745438	NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F	52679	39	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific placenta development sprouting angiogenesis sprouting angiogenesis DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus cell cycle negative regulation of cell population proliferation negative regulation of cell population proliferation nuclear speck DNA damage response, signal transduction by p53 class mediator negative regulation of cytokinesis positive regulation of DNA endoreduplication identical protein binding positive regulation of transcription by RNA polymerase II trophoblast giant cell differentiation chorionic trophoblast cell differentiation hepatocyte differentiation negative regulation of transcription involved in G1/S transition of mitotic cell cycle RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding negative regulation of G1/S transition of mitotic cell cycle
TC0400000530.mm.2	Stx17	syntaxin 17	4	48124918	NM_026343, BC028639 NM_026343, BC028639	67727	23	SNARE binding SNARE binding autophagosome membrane autophagosome membrane SNAP receptor activity SNAP receptor activity cytoplasm autophagosome autophagosome endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment cytosol plasma membrane intracellular protein transport exocytosis endoplasmic reticulum to Golgi vesicle-mediated transport vesicle fusion autophagy Golgi organization endomembrane system membrane integral component of membrane vesicle-mediated transport autophagosome membrane docking protein kinase binding protein phosphatase binding COPII-coated ER to Golgi transport vesicle smooth endoplasmic reticulum membrane HOPS complex SNARE complex SNARE complex cytoplasmic vesicle protein localization to phagophore assembly site mitochondria-associated endoplasmic reticulum membrane vesicle docking endoplasmic reticulum-Golgi intermediate compartment organization autophagosome maturation	04130
TC0600003000.mm.2	Bms1	BMS1, ribosome biogenesis factor	6	-118383380	NM_194339, BC057054 NM_194339, BC057054	213895	17	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleoplasm chromosome nucleolus 90S preribosome U3 snoRNA binding	03008
TC0200005489.mm.2	Zfp965	zinc finger protein 965	2	175470024	NM_001242944	100503949	1	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific nucleoplasm regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding
TC0800001245.mm.2	Slc7a6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	8	106168853, 106168920	NM_178798, BC038404 NM_178798, BC038404	330836	20	amino acid transmembrane transport plasma membrane amino acid transport basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity antiporter activity ornithine transport membrane integral component of membrane transmembrane transporter activity intracellular membrane-bounded organelle transmembrane transport basic amino acid transmembrane transport
TC1500001698.mm.2	Slc45a4	solute carrier family 45, member 4	15	-73577423, -73577423, -73577423	NM_001033219, NM_001168255, BC056501 NM_001033219, NM_001168255, BC056501 NM_001033219, NM_001168255, BC056501	106068	24	sucrose:proton symporter activity sucrose:proton symporter activity sucrose transport membrane integral component of membrane
MG-1-pos-10340825_st
TC0700001131.mm.2	Ticrr	TOPBP1-interacting checkpoint and replication regulator	7	79660195	NM_029835, BC158103 NM_029835, BC158103	77011	18	chromatin binding chromatin binding nucleus nucleus nucleoplasm cytosol DNA replication DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint response to ionizing radiation regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation mitotic DNA replication checkpoint intracellular membrane-bounded organelle
TC0800001639.mm.2	Shcbp1	Shc SH2-domain binding protein 1	8	-4735975	NM_011369, BC070455 NM_011369, BC070455	20419	24	protein binding cellular_component cytoplasm cytoskeleton fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway SH2 domain binding regulation of neural precursor cell proliferation
MG-1-pos-10342215_st
TC1100001899.mm.2	Nup85	nucleoporin 85	11	115564443	NM_001002929, BC079856 NM_001002929, BC079856	445007	21	chromosome, centromeric region kinetochore nucleus nuclear pore nucleoplasm chromosome cytoplasm cytosol cytoskeleton plasma membrane mRNA export from nucleus protein import into nucleus chemotaxis protein transport membrane structural constituent of nuclear pore cytokine-mediated signaling pathway lamellipodium assembly nuclear pore outer ring nuclear pore outer ring CCR2 chemokine receptor binding positive regulation of transcription, DNA-templated macrophage chemotaxis mRNA transport nephron development	03013
TC0900001441.mm.2	Nme6	NME/NM23 nucleoside diphosphate kinase 6	9	109832793	NM_018757, BC002007, NME/NM23 NM_018757, BC002007, NME/NM23 NM_018757, BC002007, NME/NM23	54369	23	nucleotide binding nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding mitochondrion mitochondrion mitochondrion nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process kinase activity phosphorylation transferase activity negative regulation of cell growth negative regulation of cell growth negative regulation of mitotic nuclear division negative regulation of mitotic nuclear division metal ion binding	00230 00240 01100
TC1600002056.mm.2	Urb1	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)	16	-90751526	NM_029497	207932	16	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleus nucleolus nucleolus
TC1400000858.mm.2	Sacs	sacsin	14	61138456, 61138456	NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956	50720	26	cytoplasm Hsp70 protein binding low-density lipoprotein particle receptor binding chaperone binding
TC0700002744.mm.2	Zfp146	zinc finger protein 146	7	-30160486	NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039	26465	22	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleic acid binding DNA binding nucleus nucleolus cytosol regulation of transcription by RNA polymerase II metal ion binding
TC0200004589.mm.2
TC0200000352.mm.2	Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	2	22774326	NM_019456, BC023110 NM_019456, BC023110	54519	28	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell protein binding cytoplasm cytosol cytosol cytosol cytoskeleton plasma membrane plasma membrane plasma membrane signal transduction membrane cell junction T cell receptor complex cell projection positive regulation of cell adhesion
TC0900002613.mm.2	Tcf12	transcription factor 12	9	-71844251, -71844251, -71844251	NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097	21406	124	chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of transcription by RNA polymerase II multicellular organism development nervous system development transcription factor binding positive regulation of gene expression nuclear speck cell differentiation cAMP response element binding intracellular membrane-bounded organelle bHLH transcription factor binding positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II SMAD binding protein heterodimerization activity protein dimerization activity E-box binding HMG box domain binding RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding
TC0800001204.mm.2	Cbfb	core binding factor beta	8	105170673	NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752	12400	145	negative regulation of transcription by RNA polymerase II protein polyubiquitination ossification osteoblast differentiation DNA binding transcription coactivator activity protein binding nucleus nucleoplasm regulation of transcription by RNA polymerase II core-binding factor complex core-binding factor complex lymphocyte differentiation myeloid cell differentiation protein-containing complex negative regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding sequence-specific DNA binding positive regulation of transcription by RNA polymerase II cell maturation definitive hemopoiesis
TC1000001868.mm.2	Eya4	EYA transcriptional coactivator and phosphatase 4	10	-23102961, -23102961	NM_010167, BC120898, BC120899 NM_010167, BC120898, BC120899 NM_010167, BC120898, BC120899	14051	28	phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus cytoplasm DNA repair chromatin organization cellular response to DNA damage stimulus multicellular organism development sensory perception of sound transcription factor binding histone dephosphorylation hydrolase activity cell differentiation middle ear morphogenesis positive regulation of DNA repair metal ion binding anatomical structure development negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
MG-1-neg-10339405_st
MG-1-pos-10343496_st
TC0800002618.mm.2	Neto2	neuropilin (NRP) and tolloid (TLL)-like 2	8	-85636717, -85636717	NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139	74513	35	plasma membrane postsynaptic density membrane integral component of membrane ionotropic glutamate receptor binding synapse regulation of kainate selective glutamate receptor activity
MG-1-neg-10338964_st
TC1100000407.mm.2	Nudcd2	NudC domain containing 2	11	40733660	NM_026023, BC005646 NM_026023, BC005646	52653	19	chromosome, centromeric region kinetochore chromosome cytoplasm cytosol cytoskeleton protein folding microtubule cytoskeleton intercellular bridge unfolded protein binding mitotic spindle
MG-1-neg-10344006_st
TC0100003887.mm.2	Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	1	-170315466, -170315466	NM_001109985, NM_027528, BC160272 NM_001109985, NM_027528, BC160272 NM_001109985, NM_027528, BC160272	70729	28	protease binding nucleus cytoplasm mitochondrion cytosol caveola biological_process Z disc PDZ domain binding T-tubule nuclear membrane sarcoplasmic reticulum membrane nitric-oxide synthase binding nitric-oxide synthase binding nitric-oxide synthase binding presynapse postsynapse glutamatergic synapse negative regulation of neuron death regulation of high voltage-gated calcium channel activity inward rectifier potassium channel complex L-type voltage-gated calcium channel complex positive regulation of peptidyl-cysteine S-nitrosylation
TC0100001595.mm.2	Cd244a	CD244 molecule A	1	171559192	NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244	18106	80	myeloid dendritic cell activation adaptive immune response natural killer cell activation involved in immune response natural killer cell activation involved in immune response immune system process protein binding plasma membrane immune response external side of plasma membrane external side of plasma membrane membrane integral component of membrane positive regulation of interferon-gamma production positive regulation of interleukin-8 production positive regulation of natural killer cell proliferation signaling receptor activity MHC class I protein binding innate immune response positive regulation of inositol phosphate biosynthetic process positive regulation of granzyme B production positive regulation of CD8-positive, alpha-beta T cell proliferation	04650
TC0200000274.mm.2	Plxdc2	plexin domain containing 2	2	16356303	NM_026162, BC057881 NM_026162, BC057881	67448	29	plasma membrane membrane integral component of membrane collagen-containing extracellular matrix
TC1100004268.mm.2	Fbxw10	F-box and WD-40 domain protein 10	11	62847122	NM_001033669, BC141212, BC172760 NM_001033669, BC141212, BC172760 NM_001033669, BC141212, BC172760	213980	13	cellular_component biological_process
TC0200002844.mm.2	Rpp38	ribonuclease P/MRP 38 subunit	2	-3328948	NM_001013376, BC051448 NM_001013376, BC051448	227522	15	fibrillar center fibrillar center tRNA 5'-leader removal tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity nucleus nucleolus rRNA processing tRNA processing hydrolase activity multimeric ribonuclease P complex multimeric ribonuclease P complex ribonuclease P RNA binding ribonuclease P RNA binding	03008 03013
TC1100000164.mm.2	Fbxo48	F-box protein 48	11	16951409, 16951374	NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591	319701	10	molecular_function SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
TC1100002486.mm.2	Npm1	nucleophosmin 1	11	-33152497, -33154924	NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378	18148	155	ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus ribosomal small subunit export from nucleus cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) core promoter sequence-specific DNA binding regulation of cell growth granular component p53 binding nucleic acid binding DNA binding chromatin binding transcription coactivator activity RNA binding RNA binding RNA binding protein kinase inhibitor activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleus nucleoplasm nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm centrosome centrosome centrosome cytosol cytoskeleton DNA repair nucleosome assembly chromatin remodeling rRNA export from nucleus rRNA export from nucleus rRNA export from nucleus cell volume homeostasis cell volume homeostasis nucleocytoplasmic transport nucleocytoplasmic transport centrosome cycle cell aging protein localization protein localization transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation rRNA transcription posttranscriptional regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication regulation of centrosome duplication positive regulation of centrosome duplication negative regulation of centrosome duplication large ribosomal subunit small ribosomal subunit nuclear matrix nuclear speck rRNA binding enzyme binding protein kinase binding Tat protein binding positive regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process positive regulation of protein ubiquitination spindle pole centrosome regulation of protein stability protein destabilization regulation of endodeoxyribonuclease activity protein-containing complex protein-DNA complex activating transcription factor binding cellular response to UV ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis histone binding histone binding identical protein binding identical protein binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of catalytic activity protein kinase B binding regulation of DNA damage response, signal transduction by p53 class mediator regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of protein kinase activity by regulation of protein phosphorylation positive regulation of translation positive regulation of DNA replication positive regulation of protein kinase activity positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of centriole replication protein N-terminus binding negative regulation of mRNA splicing, via spliceosome negative regulation of epithelial cell proliferation protein stabilization protein stabilization positive regulation of DNA metabolic process NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity regulation of cell cycle regulation of endoribonuclease activity regulation of eIF2 alpha phosphorylation by dsRNA positive regulation of DNA-directed DNA polymerase activity regulation of mRNA stability involved in cellular response to UV positive regulation of cell cycle G2/M phase transition positive regulation of protein localization to nucleolus ribonucleoprotein complex ribonucleoprotein complex
TC0400000484.mm.2	Polr1e	polymerase (RNA) I polypeptide E	4	45018608	NM_001285800, NM_022811, BC034783 NM_001285800, NM_022811, BC034783 NM_001285800, NM_022811, BC034783	64424	30	RNA polymerase I general transcription initiation factor binding RNA polymerase I preinitiation complex assembly RNA polymerase I preinitiation complex assembly fibrillar center DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm nucleoplasm nucleolus RNA polymerase I complex RNA polymerase I complex transcription, DNA-templated transcription elongation from RNA polymerase I promoter nucleolar large rRNA transcription by RNA polymerase I nucleolar large rRNA transcription by RNA polymerase I	00230 00240 01100 03020
TC0300001587.mm.2	Depdc1a	DEP domain containing 1a	3	159495432	NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934	76131	12	GTPase activator activity nucleus nucleus signal transduction transcription repressor complex transcription repressor complex intracellular signal transduction negative regulation of transcription, DNA-templated
TC0200002720.mm.2					NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II
TC0200002738.mm.2					NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II
TC0200005341.mm.2					NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068			RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II
TC1500001202.mm.2	Brix1	BRX1, biogenesis of ribosomes	15	-10474778	NM_026396, BC014832 NM_026396, BC014832	67832	23	ribosomal large subunit assembly RNA binding nucleus chromosome nucleolus nucleolus ribosome biogenesis
TC0200000473.mm.2	Wdr5	WD repeat domain 5	2	27515146	NM_080848, BC016103, BC025801 NM_080848, BC016103, BC025801 NM_080848, BC016103, BC025801	140858	64	histone acetyltransferase complex skeletal system development protein binding intracellular anatomical structure nucleus nucleus nucleoplasm nucleoplasm Ada2/Gcn5/Ada3 transcription activator complex Ada2/Gcn5/Ada3 transcription activator complex chromatin organization neuron projection development methylated histone binding histone methyltransferase complex histone binding histone methyltransferase activity (H3-K4 specific) histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K16 acetylation MLL3/4 complex positive regulation of gluconeogenesis Set1C/COMPASS complex Set1C/COMPASS complex histone H3-K4 methylation histone H3-K4 methylation histone H3-K4 methylation positive regulation of histone H3-K4 methylation negative regulation of histone H3-K4 methylation MLL1 complex
TC1700001439.mm.2	Pacrg	PARK2 co-regulated	17	-10403011	NM_027032, BC120740 NM_027032, BC120740	69310	35	G protein-coupled receptor binding manchette actin binding protein binding mitochondrion cytosol cytosol cytosol cilium spermatid development Hsp70 protein binding Hsp70 protein binding heat shock protein binding ubiquitin protein ligase binding ubiquitin protein ligase binding vesicle vesicle vesicle cellular protein localization cellular response to unfolded protein neuron projection neuron projection neuron projection alpha-tubulin binding cell body beta-tubulin binding chaperone binding chaperone binding Hsp90 protein binding Hsp90 protein binding negative regulation of cell death negative regulation of cell death negative regulation of cell death sperm midpiece
TC0X00000958.mm.2	Kif4	kinesin family member 4	X	100626064	NM_008446, BC050946 NM_008446, BC050946	16571	43	nucleotide binding mitotic cytokinesis DNA binding microtubule motor activity ATP binding nucleus nucleoplasm chromosome cytoplasm cytosol cytoskeleton microtubule microtubule-based movement mitotic spindle organization microtubule binding midbody metal ion binding mitotic spindle midzone assembly iron-sulfur cluster binding
TC0100001240.mm.2	Ube2t	ubiquitin-conjugating enzyme E2T	1	134962564	NM_001278115, NM_026024, BC029213 NM_001278115, NM_026024, BC029213 NM_001278115, NM_026024, BC029213	67196	19	nucleotide binding protein polyubiquitination chromatin binding ubiquitin-protein transferase activity ATP binding nucleus nucleoplasm nucleolus DNA repair protein monoubiquitination cellular response to DNA damage stimulus cellular response to DNA damage stimulus transferase activity ubiquitin protein ligase binding protein K29-linked ubiquitination protein K27-linked ubiquitination protein autoubiquitination ubiquitin conjugating enzyme activity ubiquitin conjugating enzyme activity protein K63-linked ubiquitination protein K48-linked ubiquitination protein K11-linked ubiquitination protein K6-linked ubiquitination
TC0900000819.mm.2	Tipin	timeless interacting protein	9	64281584	NM_025372, BC016211 NM_025372, BC016211	66131	25	DNA replication checkpoint DNA replication checkpoint DNA damage checkpoint chromatin DNA binding protein binding nucleus nucleus cytoplasm cellular response to DNA damage stimulus cell cycle positive regulation of cell population proliferation response to UV replication fork protection complex intra-S DNA damage checkpoint replication fork arrest cell cycle phase transition replication fork protection cell division
TC0X00000429.mm.2	Utp14a	UTP14A small subunit processome component	X	48256933	NM_028276, BC082590 NM_028276, BC082590	72554	22	nucleus nucleolus nucleolus cytosol rRNA processing small-subunit processome ribosome biogenesis	03008
TC1900001089.mm.2	Incenp	inner centromere protein	19	-9872294	NM_016692, BC052414 NM_016692, BC052414	16319	37	mitotic sister chromatid segregation mitotic cytokinesis mitotic cytokinesis chromosome, centromeric region chromosome, centromeric region kinetochore kinetochore condensed chromosome synaptonemal complex lateral element central element nucleus nucleoplasm chromosome pericentric heterochromatin cytoplasm spindle cytosol cytoskeleton microtubule cell cycle chromosome segregation meiotic chromosome condensation chromocenter histone phosphorylation nuclear body midbody midbody midbody chromosome passenger complex protein-containing complex protein serine/threonine kinase activator activity meiotic spindle midzone assembly cell division metaphase plate congression positive regulation of protein serine/threonine kinase activity regulation of mitotic cytokinesis meiotic spindle midzone
TC0400000309.mm.2	Rars2	arginyl-tRNA synthetase 2, mitochondrial	4	34614956	NM_181406, BC024878 NM_181406, BC024878	109093	23	nucleotide binding aminoacyl-tRNA ligase activity arginine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrion translation tRNA aminoacylation for protein translation arginyl-tRNA aminoacylation ligase activity mitochondrial translation	00970
TC1600000376.mm.2	Il1rap	interleukin 1 receptor accessory protein	16	26581704, 26581704, 26581704, 26581704	NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159	16180	51	interleukin-33 receptor activity immune system process interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1 receptor binding interleukin-1 receptor binding protein binding extracellular region cytoplasm plasma membrane inflammatory response signal transduction membrane integral component of membrane hydrolase activity cytokine-mediated signaling pathway interleukin-2 production interleukin-4 production positive regulation of interleukin-13 production positive regulation of interleukin-5 production positive regulation of interleukin-6 production protein-containing complex interleukin-33-mediated signaling pathway innate immune response NAD(P)+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of synapse assembly NAD+ nucleotidase, cyclic ADP-ribose generating glutamatergic synapse glutamatergic synapse regulation of postsynaptic density assembly regulation of postsynaptic density assembly trans-synaptic signaling by trans-synaptic complex trans-synaptic signaling by trans-synaptic complex synaptic membrane adhesion synaptic membrane adhesion positive regulation of dendrite development regulation of presynapse assembly regulation of presynapse assembly protein tyrosine kinase binding	04060 04210
TC0400001736.mm.2	Pla2g2e	phospholipase A2, group IIE	4	138877941	NM_012044, BC027524 NM_012044, BC027524	26970	28	phospholipase A2 activity calcium ion binding calcium ion binding phospholipid binding extracellular region cytoplasm lipid metabolic process phospholipid metabolic process inflammatory response lipid catabolic process hydrolase activity low-density lipoprotein particle remodeling phosphatidylcholine metabolic process phosphatidylglycerol metabolic process metal ion binding calcium-dependent phospholipase A2 activity calcium-dependent phospholipase A2 activity calcium-dependent phospholipase A2 activity arachidonic acid secretion	00564 00565 00590 00591 00592 01100 04010 04270 04370 04664 04730 04912 04972 04975 05145
TC1800001156.mm.2	Cdc25c	cell division cycle 25C	18	-34732994	NM_009860, BC004669 NM_009860, BC004669	12532	51	G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding intracellular anatomical structure nucleus nucleus nucleus cytoplasm cytoplasm mitochondrial intermembrane space protein dephosphorylation cell cycle positive regulation of G2/M transition of mitotic cell cycle nuclear speck hydrolase activity protein kinase binding perinuclear region of cytoplasm WW domain binding cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition	04110 04114 04914
TC0800003008.mm.2	Gcsh	glycine cleavage system protein H (aminomethyl carrier)	8	-116981966	NM_026572, BC014745 NM_026572, BC014745	68133	19	aminomethyltransferase activity cytoplasm mitochondrion mitochondrion mitochondrion glycine cleavage complex protein lipoylation protein lipoylation glycine decarboxylation via glycine cleavage system glycine decarboxylation via glycine cleavage system enzyme binding
TC1400000177.mm.2	Vcl	vinculin	14	20929397	NM_009502, BC008520 NM_009502, BC008520	22330	214	stress fiber morphogenesis of an epithelium podosome dystroglycan binding actin binding structural molecule activity protein binding cytoplasm cytoskeleton actin filament plasma membrane cell-cell junction cell-cell junction adherens junction adherens junction fascia adherens focal adhesion focal adhesion cell adhesion intercalated disc actin cytoskeleton membrane Z disc lamellipodium assembly cell junction regulation of cell migration small GTPase binding ubiquitin protein ligase binding protein-containing complex adherens junction assembly protein localization to cell surface sarcolemma sarcolemma costamere costamere apical junction assembly cell-cell contact zone membrane raft alpha-catenin binding axon extension actin filament binding regulation of focal adhesion assembly epithelial cell-cell adhesion regulation of establishment of endothelial barrier regulation of protein localization to adherens junction	04510 04520 04670 04810 05100 05146
MG-1-pos-10343924_st
TC0500000048.mm.2	Slc25a40	solute carrier family 25, member 40	5	8422837	NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103	319653	15	mitochondrion mitochondrial inner membrane membrane integral component of membrane transmembrane transporter activity transmembrane transport
TC0200001756.mm.2	Rpusd2	RNA pseudouridylate synthase domain containing 2	2	119034789	NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828	271842	13	enzyme-directed rRNA pseudouridine synthesis pseudouridine synthesis RNA binding RNA modification pseudouridine synthase activity
TC0500003096.mm.2	Gatc	glutamyl-tRNA(Gln) amidotransferase, subunit C	5	-115333241	NM_029645, BC021775 NM_029645, BC021775	384281	14	nucleotide binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion translation regulation of translational fidelity ligase activity glutamyl-tRNA(Gln) amidotransferase complex glutamyl-tRNA(Gln) amidotransferase complex mitochondrial translation mitochondrial translation glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNAGln biosynthesis via transamidation glutaminyl-tRNAGln biosynthesis via transamidation
TC0400003437.mm.2	Ctps	cytidine 5'-triphosphate synthase	4	-120539867, -120539867	NM_016748, BC006698 NM_016748, BC006698	51797	30	nucleotide binding immune system process CTP synthase activity CTP synthase activity ATP binding cytoplasm pyrimidine nucleotide biosynthetic process CTP biosynthetic process CTP biosynthetic process glutamine metabolic process ligase activity pyrimidine nucleobase biosynthetic process T cell proliferation B cell proliferation identical protein binding identical protein binding cytoophidium cytoophidium	00240 01100
TC1100001329.mm.2	Ska2	spindle and kinetochore associated complex subunit 2	11	87109260	NM_025377, BC117001, BC119167 NM_025377, BC117001, BC119167 NM_025377, BC117001, BC119167	66140	23	mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore chromosome cytoplasm cytoskeleton microtubule spindle microtubule spindle microtubule cell cycle chromosome segregation chromosome segregation microtubule binding microtubule binding regulation of microtubule polymerization or depolymerization cell division
TC0200003202.mm.2	Surf6	surfeit gene 6	2	-26890417	NM_009298, BC037634 NM_009298, BC037634	20935	30	granular component DNA binding DNA binding RNA binding RNA binding nucleus nucleoplasm nucleoplasm chromosome nucleolus nucleolus nucleolus ribosome biogenesis ribosome assembly ribosomal large subunit biogenesis ribosomal small subunit biogenesis
TC1500001534.mm.2	Dscc1	DNA replication and sister chromatid cohesion 1	15	-55076100	NM_183089, BC116833, BC116835 NM_183089, BC116833, BC116835 NM_183089, BC116833, BC116835	72107	16	chromosome, centromeric region chromosome, centromeric region chromatin chromatin DNA binding DNA clamp loader activity DNA clamp loader activity nucleus nucleoplasm DNA replication regulation of DNA replication regulation of DNA replication cell cycle mitotic sister chromatid cohesion single-stranded DNA helicase activity Ctf18 RFC-like complex Ctf18 RFC-like complex maintenance of mitotic sister chromatid cohesion maintenance of mitotic sister chromatid cohesion post-translational protein acetylation positive regulation of DNA-directed DNA polymerase activity
TC0600003342.mm.2	Eps8	epidermal growth factor receptor pathway substrate 8	6	-137477244, -137477244, -137477244	NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890	13860	73	actin binding actin binding protein binding cytoplasm plasma membrane brush border cell cortex Rho protein signal transduction adult locomotory behavior regulation of cell shape exit from mitosis postsynaptic density postsynaptic density membrane Rac protein signal transduction NMDA selective glutamate receptor complex cell junction regulation of actin filament length small GTPase binding actin cytoskeleton reorganization stereocilium stereocilium bundle stereocilium tip ruffle membrane ruffle membrane regulation of Rho protein signal transduction signaling adaptor activity dendritic cell migration cell projection neuron projection synapse behavioral response to ethanol barbed-end actin filament capping barbed-end actin filament capping actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly actin crosslink formation actin crosslink formation actin polymerization-dependent cell motility glutamatergic synapse glutamatergic synapse glutamatergic synapse regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels positive regulation of ruffle assembly cellular response to leukemia inhibitory factor
TC1100003569.mm.2	Eme1	essential meiotic structure-specific endonuclease 1	11	-94644972, -94644995	NM_177752, BC089459 NM_177752, BC089459	268465	26	resolution of meiotic recombination intermediates chromatin heterochromatin DNA binding nuclease activity endonuclease activity protein binding nucleus DNA repair double-strand break repair DNA recombination cellular response to DNA damage stimulus hydrolase activity replication fork processing intra-S DNA damage checkpoint metal ion binding Holliday junction resolvase complex response to intra-S DNA damage checkpoint signaling	03440
TC1700002561.mm.2	Cebpz	CCAAT/enhancer binding protein zeta	17	-78919002	NM_001024806, BC160197 NM_001024806, BC160197	12607	24	transcription coactivator activity nucleus nucleus ribosome biogenesis positive regulation of transcription by RNA polymerase II
TC1900001428.mm.2	Pank1	pantothenate kinase 1	19	-34806935, -34806935	NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496	75735	33	nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus nucleus nucleus cytosol cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity clathrin coat protein homodimerization activity recycling endosome cell periphery acetyl-CoA binding	00770 01100
TC0100001178.mm.2	Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	1	131910457	NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951	98415	32	double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromatin chromatin cellular glucose homeostasis chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding transcription coactivator activity nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cytoplasm cytoplasm regulation of DNA replication DNA repair chromatin organization regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus transcription factor binding release from viral latency replication fork processing interstrand cross-link repair interstrand cross-link repair glucose homeostasis positive regulation by host of viral transcription positive regulation by host of viral genome replication positive regulation of transcription by RNA polymerase II regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway regulation of DNA strand elongation cellular response to X-ray modulation by host of RNA binding by virus modulation by host of viral RNA-binding transcription factor activity
TC1800000535.mm.2	Snx24	sorting nexing 24	18	53245624	NM_029394, BC051168 NM_029394, BC051168	69226	15	cellular_component biological_process lipid binding phosphatidylinositol-5-phosphate binding protein transport membrane cytoplasmic vesicle phosphatidylinositol-3-phosphate binding phosphatidylinositol binding phosphatidylinositol-4-phosphate binding phosphatidylinositol phosphate binding
TC1600000952.mm.2	N6amt1	N-6 adenine-specific DNA methyltransferase 1 (putative)	16	87354184	NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394	67768	20	nucleic acid binding protein binding nucleus chromatin organization methyltransferase activity protein methyltransferase activity protein methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity toxin metabolic process transferase activity histone-lysine N-methyltransferase activity peptidyl-glutamine methylation peptidyl-glutamine methylation arsonoacetate metabolic process positive regulation of cell growth methylarsonite methyltransferase activity methylation protein-containing complex histone lysine methylation eRF1 methyltransferase complex protein-glutamine N-methyltransferase activity protein-glutamine N-methyltransferase activity S-adenosyl-L-methionine binding
TC0200000312.mm.2	Msrb2	methionine sulfoxide reductase B2	2	19371635	NM_029619, BC021619 NM_029619, BC021619	76467	30	actin binding cytoplasm mitochondrion mitochondrion response to oxidative stress zinc ion binding oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor actin filament polymerization protein repair peptide-methionine (R)-S-oxide reductase activity peptide-methionine (R)-S-oxide reductase activity L-methionine-(R)-S-oxide reductase activity metal ion binding
TC0300000880.mm.2	Selenbp1	selenium binding protein 1	3	94933082	NM_009150, BC011202 NM_009150, BC011202	20341	31	fibrillar center nucleus nucleolus cytoplasm selenium binding protein transport membrane oxidoreductase activity methanethiol oxidase activity brown fat cell differentiation
TC1100003300.mm.2	Tmem97	transmembrane protein 97	11	-78541816	NM_133706, BC018156, BC093511 NM_133706, BC018156, BC093511 NM_133706, BC018156, BC093511	69071	23	molecular_function nucleus lysosome endoplasmic reticulum endoplasmic reticulum rough endoplasmic reticulum plasma membrane membrane integral component of membrane nuclear membrane cholesterol homeostasis
TC1800000908.mm.2					NM_175542, NR_105777 NM_175542, NR_105777			molecular_function cytoplasm centrosome centriole cytoskeleton cilium centriole replication multicellular organism development determination of left/right symmetry centriole-centriole cohesion integral component of membrane ciliary basal body organization ciliary basal body ciliary basal body cell projection cilium organization
TC0700003599.mm.2	Wdr73	WD repeat domain 73	7	-80890722	NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940	71968	20	spindle pole spindle pole molecular_function cytoplasm cytosol cytosol cytoskeleton nucleus organization cytoplasmic microtubule organization cytoplasmic microtubule organization cleavage furrow negative regulation of apoptotic process
TC0400000091.mm.2					NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604			double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination nucleus nucleus nucleoplasm cellular response to DNA damage stimulus cellular response to DNA damage stimulus reciprocal meiotic recombination biological_process determination of adult lifespan response to ionizing radiation response to ionizing radiation DNA translocase activity DNA translocase activity response to drug identical protein binding
TC0800000646.mm.2	Mfap3l	microfibrillar-associated protein 3-like	8	60632824, 60655103, 60655556	NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950	71306	14	molecular_function nucleus nucleus nucleoplasm cytoplasm cytoplasm plasma membrane plasma membrane biological_process membrane integral component of membrane cell junction
TC1100003505.mm.2	Akap1	A kinase (PRKA) anchor protein 1	11	-88830791, -88830791, -88830791	NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310	11640	58	nucleic acid binding RNA binding protein binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum lipid droplet apoptotic process microtubule binding negative regulation of cardiac muscle hypertrophy regulation of protein kinase A signaling membrane integral component of membrane protein kinase binding protein phosphatase binding mitochondrial crista protein phosphatase 2B binding neuromuscular junction protein kinase A regulatory subunit binding negative regulation of protein dephosphorylation negative regulation of protein import into nucleus postsynaptic membrane beta-tubulin binding molecular adaptor activity antiviral innate immune response
MG-1-pos-10343025_st
TC0200000459.mm.2	Surf2	surfeit gene 2	2	26916407	NM_013678, BC096401 NM_013678, BC096401	20931	21	molecular_function nucleoplasm nucleolus plasma membrane biological_process nuclear speck
MG-1-neg-10340688_st
TC1300002617.mm.2	Ipo11	importin 11	13	-106794438	NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943	76582	23	protein binding nucleus nuclear envelope nucleoplasm cytoplasm cytosol cytosol protein import into nucleus ribosomal protein import into nucleus intracellular protein transport protein transport small GTPase binding nuclear import signal receptor activity
TC0600001744.mm.2	Klhl42	kelch-like 42	6	147091074	NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076	232539	16	protein polyubiquitination protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoskeleton cell cycle Cul3-RING ubiquitin ligase complex regulation of microtubule-based process regulation of microtubule-based process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division
TC1700000705.mm.2	Mdc1	mediator of DNA damage checkpoint 1	17	35841497	NM_001010833	240087	55	nucleus nucleoplasm chromosome focal adhesion DNA repair cellular response to DNA damage stimulus cell cycle protein C-terminus binding nuclear body identical protein binding FHA domain binding
TC0X00002631.mm.2	Pola1	polymerase (DNA directed), alpha 1	X	-93304765	NM_008892, BC138047 NM_008892, BC138047	18968	36	nucleotide binding DNA synthesis involved in DNA repair chromatin nucleoside binding nucleic acid binding DNA binding chromatin binding chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity protein binding nucleus nucleus nuclear envelope nucleoplasm alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex nucleolus cytoplasm cytosol DNA replication DNA replication DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication initiation DNA strand elongation involved in DNA replication leading strand elongation leading strand elongation lagging strand elongation lagging strand elongation double-strand break repair via nonhomologous end joining nuclear matrix transferase activity nucleotidyltransferase activity purine nucleotide binding purine nucleotide binding pyrimidine nucleotide binding pyrimidine nucleotide binding protein kinase binding regulation of type I interferon production metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding DNA biosynthetic process mitotic DNA replication initiation	00230 00240 01100 03030
TC1600000176.mm.2	Nde1	nudE neurodevelopment protein 1	16	14163274	NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267	67203	49	establishment of mitotic spindle orientation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore neuron migration protein binding chromosome cytoplasm centrosome centrosome centrosome microtubule organizing center spindle cytoskeleton kinesin complex microtubule microtubule nucleation microtubule nucleation cell cycle chromosome segregation mitotic centrosome separation multicellular organism development nervous system development neuroblast proliferation microtubule binding microtubule binding cell migration protein domain specific binding cerebral cortex development cerebral cortex development cell differentiation forebrain development microtubule organizing center organization spindle pole centrosome identical protein binding identical protein binding synapse vesicle transport along microtubule vesicle transport along microtubule centrosome duplication cell division establishment of chromosome localization establishment of chromosome localization centrosome localization regulation of microtubule motor activity
TC0200000055.mm.2	Nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5	2	5845033	NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595	53893	28	magnesium ion binding RNA binding nucleus nucleus nucleobase-containing compound metabolic process chromatin remodeling nucleoside phosphate metabolic process ribonucleoside diphosphate catabolic process transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-diphosphatase activity ADP-sugar diphosphatase activity D-ribose catabolic process ribose phosphate metabolic process snoRNA binding identical protein binding protein homodimerization activity 8-oxo-dGDP phosphatase activity metal ion binding ADP-ribose diphosphatase activity ADP-ribose diphosphatase activity ATP generation from poly-ADP-D-ribose	00230
TC0100003866.mm.2	Serpinb2	serine (or cysteine) peptidase inhibitor, clade B, member 2	1	107511509, 107511422	NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817	18788	55	serine-type endopeptidase inhibitor activity extracellular region extracellular space cytoplasm negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity wound healing negative regulation of apoptotic process	05146
TC1200001420.mm.2	Gen1	GEN1, Holliday junction 5' flap endonuclease	12	-11238937	NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158	209334	21	magnesium ion binding four-way junction DNA binding four-way junction DNA binding double-strand break repair via homologous recombination DNA binding catalytic activity nuclease activity endonuclease activity nucleus centrosome DNA repair cellular response to DNA damage stimulus crossover junction endodeoxyribonuclease activity regulation of centrosome duplication hydrolase activity 5'-flap endonuclease activity 5'-flap endonuclease activity replication fork processing protein homodimerization activity metal ion binding resolution of recombination intermediates resolution of mitotic recombination intermediates positive regulation of mitotic cell cycle spindle assembly checkpoint
TC0600003136.mm.2	Ncapd2	non-SMC condensin I complex, subunit D2	6	-125168006	NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133	68298	32	nuclear chromosome mitotic cell cycle condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation histone binding histone binding pronucleus cell division
MG-1-neg-10341224_st
MG-1-neg-10342714_st
MG-1-neg-10342165_st
TC0900001623.mm.2	Ss18l2	SS18, nBAF chromatin remodeling complex subunit like 2	9	121710388	NM_026794, BC027548 NM_026794, BC027548	26901	17	molecular_function transcription coactivator activity nucleus positive regulation of transcription by RNA polymerase II positive regulation of dendrite morphogenesis
TC1100002593.mm.2	Thg1l	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)	11	-45945305, -45945305	NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561	66628	16	nucleotide binding magnesium ion binding guanyl-nucleotide exchange factor activity ATP binding GTP binding cytoplasm mitochondrion tRNA modification response to oxidative stress tRNA processing tRNA processing mitochondrial fusion tRNA guanylyltransferase activity tRNA guanylyltransferase activity transferase activity nucleotidyltransferase activity identical protein binding metal ion binding protein homotetramerization stress-induced mitochondrial fusion transferase complex
TC1300000273.mm.2	Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	13	24327403, 24415121	NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079	12763	51	cytoplasm endoplasmic reticulum oxidoreductase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate metabolic process metal ion binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding	00520
TC0200001874.mm.2	Slc24a5	solute carrier family 24, member 5	2	125068126	NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643	317750	17	calcium channel activity Golgi apparatus trans-Golgi network trans-Golgi network ion transport potassium ion transport sodium ion transport calcium ion transport cellular calcium ion homeostasis calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral component of membrane melanocyte differentiation ion transmembrane transport regulation of melanin biosynthetic process negative regulation of melanin biosynthetic process response to stimulus transmembrane transport calcium ion transmembrane transport
TC0800002523.mm.2	Abce1	ATP-binding cassette, sub-family E (OABP), member 1	8	-79683441	NM_015751, BC005422 NM_015751, BC005422	24015	31	ribosomal subunit export from nucleus nucleotide binding iron ion binding ATP binding cytoplasm mitochondrion cytosol eukaryotic translation initiation factor 3 complex translational initiation translational termination ATPase activity ribosomal small subunit binding endoribonuclease inhibitor activity negative regulation of endoribonuclease activity
TC1300001922.mm.2	Kif13a	kinesin family member 13A	13	-46749087	NM_010617	16553	23	nucleotide binding microtubule motor activity microtubule motor activity protein binding ATP binding cytoplasm endosome Golgi apparatus centrosome cytoskeleton kinesin complex microtubule intracellular protein transport intracellular protein transport microtubule-based movement cell cycle microtubule binding endosome to lysosome transport endosome membrane protein transport membrane ATPase activity midbody melanosome organization regulation of cytokinesis trans-Golgi network membrane vesicle cargo loading Golgi to plasma membrane protein transport cell division plus-end-directed vesicle transport along microtubule
TC1300000715.mm.2	Rmi1	RecQ mediated genome instability 1	13	58402247, 58402596	NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694	74386	24	nucleotide binding resolution of meiotic recombination intermediates double-strand break repair via homologous recombination response to dietary excess reduction of food intake in response to dietary excess molecular_function nucleus nucleoplasm DNA replication response to glucose nuclear body nuclear body RecQ family helicase-topoisomerase III complex multicellular organism growth glucose homeostasis
TC1700000896.mm.2	Dnph1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	17	46496788	NM_207161, BC048355 NM_207161, BC048355	381101	17	nucleus nucleus cytoplasm metabolic process nucleotide metabolic process deoxyribonucleoside monophosphate catabolic process deoxyribonucleoside monophosphate catabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds positive regulation of cell growth identical protein binding protein homodimerization activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity
TC0100001756.mm.2	Taf1a	TATA-box binding protein associated factor, RNA polymerase I, A	1	183388984, 183388884	NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425	21339	19	RNA polymerase I transcription regulator complex DNA binding protein binding nucleus nucleoplasm nucleoplasm transcription by RNA polymerase I microtubule cytoskeleton
TC0X00001084.mm.2	P2ry10b	purinergic receptor P2Y, G-protein coupled 10B	X	107148926, 107149453, 107149614	NM_001122595, NM_001122596, NM_175442 NM_001122595, NM_001122596, NM_175442 NM_001122595, NM_001122596, NM_175442	213438	11	G protein-coupled receptor activity integral component of plasma membrane positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
TC1500002075.mm.2	Abcd2	ATP-binding cassette, sub-family D (ALD), member 2	15	-91145870	NM_011994, BC019187 NM_011994, BC019187	26874	52	very long-chain fatty acid metabolic process nucleotide binding long-chain fatty acid transporter activity protein binding ATP binding mitochondrion peroxisome peroxisomal membrane peroxisomal membrane fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation peroxisome organization response to bacterium long-chain fatty acid import into peroxisome membrane integral component of membrane ATPase activity positive regulation of fatty acid beta-oxidation positive regulation of fatty acid beta-oxidation ATPase-coupled transmembrane transporter activity very long-chain fatty acid catabolic process very long-chain fatty acid catabolic process very long-chain fatty acid catabolic process protein homodimerization activity myelin maintenance transmembrane transport negative regulation of cytokine production involved in inflammatory response negative regulation of reactive oxygen species biosynthetic process neuron projection maintenance positive regulation of unsaturated fatty acid biosynthetic process	02010 04146
TC1100000383.mm.2	Pank3	pantothenate kinase 3	11	35769494	NM_145962, BC027089 NM_145962, BC027089	211347	27	nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus cytoplasm cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity vitamin binding protein homodimerization activity acetyl-CoA binding	00770 01100
TC1300002380.mm.2	Rasa1	RAS p21 protein activator 1	13	-85214698	NM_145452, BC013637 NM_145452, BC013637	218397	91	ruffle phosphotyrosine residue binding positive regulation of protein phosphorylation negative regulation of cell-matrix adhesion GTPase activator activity signaling receptor binding platelet-derived growth factor receptor binding protein binding cytosol cytosol plasma membrane plasma membrane negative regulation of cell adhesion signal transduction transcription factor binding membrane kinase binding regulation of actin filament polymerization receptor tyrosine kinase binding nuclear membrane cellular response to platelet-derived growth factor stimulus response to drug negative regulation of apoptotic process protein kinase B binding positive regulation of GTPase activity ion channel binding protein-containing complex binding positive regulation of glucose import positive regulation of fibroblast proliferation blood vessel morphogenesis positive regulation of peptidyl-tyrosine phosphorylation GTPase binding cellular response to epidermal growth factor stimulus activation of GTPase activity protein tyrosine kinase binding	04010 04360
TC1300002119.mm.2	Golm1	golgi membrane protein 1	13	-59634995	NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486	105348	24	molecular_function Golgi apparatus Golgi apparatus nucleus organization membrane integral component of membrane regulation of lipid metabolic process

1021 Genes