| Probe |
Symbol |
Description |
Chromosome |
Chromosome Location |
GenBank |
Gene |
PubMed |
Gene Ontology |
Pathway |
| TC1100003401.mm.2 |
Ccl3 |
chemokine (C-C motif) ligand 3 |
11 |
-83647842 |
NM_011337, BC111443 NM_011337, BC111443 |
20302 |
260 |
monocyte chemotaxis cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity chemokine activity regulation of cell shape neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production positive regulation of neuron apoptotic process positive regulation of GTPase activity astrocyte cell migration positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II CCR chemokine receptor binding macrophage chemotaxis lymphocyte chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor |
04060 04062 04620 05142 05323 |
| TC1200000203.mm.2 |
Rrm2 |
ribonucleotide reductase M2 |
12 |
24708253 |
NM_009104, BC085136 NM_009104, BC085136 |
20135 |
72 |
blastocyst development ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding nuclear envelope cytoplasm cytosol cytosol cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication ferric iron binding deoxyribonucleotide metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity identical protein binding protein homodimerization activity metal ion binding protein heterotetramerization |
00230 00240 00480 01100 04115 |
| TC0600001606.mm.2 |
Emp1 |
epithelial membrane protein 1 |
6 |
135362930, 135367492 |
NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 |
13730 |
29 |
plasma membrane plasma membrane cell death membrane integral component of membrane cell growth bleb assembly |
|
| TC0800001737.mm.2 |
Gas6 |
growth arrest specific 6 |
8 |
-13465373 |
NM_019521, BC005444 NM_019521, BC005444 |
14456 |
109 |
neuron migration phosphatidylserine binding positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of glomerular filtration signaling receptor binding calcium ion binding extracellular region extracellular space extracellular space extracellular space cytoplasm protein phosphorylation phagocytosis signal transduction enzyme linked receptor protein signaling pathway blood coagulation cellular response to starvation positive regulation of gene expression negative regulation of tumor necrosis factor-mediated signaling pathway macrophage cytokine production peptidyl-serine phosphorylation fusion of virus membrane with host plasma membrane viral genome replication protein tyrosine kinase activator activity protein-macromolecule adaptor activity receptor tyrosine kinase binding cell-substrate adhesion positive regulation of TOR signaling activation of protein kinase B activity negative regulation of interferon-gamma production negative regulation of interleukin-1 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of natural killer cell differentiation positive regulation of peptidyl-serine phosphorylation cellular response to interferon-alpha cellular response to drug B cell chemotaxis regulation of growth cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic cell clearance apoptotic cell clearance negative regulation of DNA-binding transcription factor activity protein kinase B signaling protein kinase B signaling protein kinase B signaling protein kinase B signaling positive regulation of protein kinase activity negative regulation of transcription, DNA-templated viral entry into host cell receptor-mediated virion attachment to host cell positive regulation of protein export from nucleus metal ion binding receptor ligand activity receptor ligand activity receptor ligand activity positive regulation of fibroblast proliferation positive regulation of phagocytosis positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport cellular response to vitamin K cellular response to glucose stimulus cellular response to growth factor stimulus cellular response to growth factor stimulus protein localization to plasma membrane hematopoietic stem cell migration to bone marrow negative regulation of oligodendrocyte apoptotic process negative regulation of fibroblast apoptotic process negative regulation of endothelial cell apoptotic process positive regulation of dendritic cell chemotaxis negative regulation of dendritic cell apoptotic process |
|
| TC0400001856.mm.2 |
Dhrs3 |
dehydrogenase/reductase (SDR family) member 3 |
4 |
144893136, 144892826, 144893076 |
NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 |
20148 |
30 |
retinoid metabolic process retinoid metabolic process outflow tract morphogenesis retinol dehydrogenase activity retinol dehydrogenase activity lipid droplet membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor regulation of ossification retinol metabolic process regulation of retinoic acid receptor signaling pathway negative regulation of retinoic acid receptor signaling pathway NADP-retinol dehydrogenase activity roof of mouth development bone morphogenesis cardiac septum morphogenesis |
00830 01100 |
| TC1000000372.mm.2 |
Sesn1 |
sestrin 1 |
10 |
41810573, 41887438 |
NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 |
140742 |
33 |
fibrillar center protein binding nucleus nucleoplasm cytoplasm cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor negative regulation of cell growth TORC2 complex cellular response to amino acid starvation cellular response to glucose starvation regulation of protein kinase B signaling GATOR2 complex GATOR2 complex leucine binding leucine binding cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process cellular oxidant detoxification regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation |
04115 |
| TC0100000298.mm.2 |
Il1rl1 |
interleukin 1 receptor-like 1 |
1 |
40439628, 40439628, 40429569 |
NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445 |
17082 |
293 |
interleukin-33 binding interleukin-33 binding interleukin-33 receptor activity interleukin-33 receptor activity negative regulation of T-helper 1 type immune response interleukin-1 receptor activity protein binding extracellular region extracellular space cytosol plasma membrane focal adhesion signal transduction negative regulation of cell population proliferation external side of plasma membrane external side of plasma membrane cell surface membrane integral component of membrane hydrolase activity extracellular matrix negative regulation of interferon-gamma production positive regulation of chemokine production positive regulation of interleukin-5 production positive regulation of macrophage activation negative regulation of I-kappaB kinase/NF-kappaB signaling NAD(P)+ nucleosidase activity positive regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating |
|
| TC0400001639.mm.2 |
Stmn1 |
stathmin 1 |
4 |
134468319 |
NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 |
16765 |
112 |
mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm cytoplasm cytosol cytoskeleton microtubule microtubule depolymerization microtubule depolymerization mitotic spindle organization multicellular organism development nervous system development axonogenesis tubulin binding tubulin binding membrane cell differentiation regulation of microtubule polymerization or depolymerization regulation of microtubule polymerization or depolymerization negative regulation of microtubule polymerization negative regulation of microtubule polymerization neuron projection development negative regulation of Rho protein signal transduction neuron projection hepatocyte growth factor receptor signaling pathway positive regulation of cellular component movement negative regulation of stress fiber assembly establishment of skin barrier negative regulation of thrombin-activated receptor signaling pathway negative regulation of guanyl-nucleotide exchange factor activity |
04010 |
| TC0500003472.mm.2 |
|
|
|
|
NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 |
|
|
nucleotide binding double-strand break repair via break-induced replication in utero embryonic development negative regulation of B cell apoptotic process DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytosol DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cellular response to DNA damage stimulus cell cycle cell aging sensory perception of sound cell population proliferation Wnt signaling pathway hydrolase activity regulation of phosphorylation MCM complex MCM complex negative regulation of apoptotic process regulation of viral genome replication regulation of viral genome replication long-term synaptic potentiation SMAD protein signal transduction cellular response to inorganic substance cellular response to xenobiotic stimulus cellular response to forskolin single-stranded 3'-5' DNA helicase activity |
|
| TC0400001934.mm.2 |
Srm |
spermidine synthase |
4 |
148591512 |
NM_009272, BC005566 NM_009272, BC005566 |
20810 |
24 |
catalytic activity spermidine synthase activity spermidine synthase activity polyamine metabolic process polyamine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process transferase activity identical protein binding protein homodimerization activity cellular response to leukemia inhibitory factor |
00270 00330 00410 00480 01100 |
| TC1400000176.mm.2 |
Plau |
plasminogen activator, urokinase |
14 |
20836661 |
NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713 |
18792 |
311 |
angiogenesis response to hypoxia serine-type endopeptidase activity protein binding extracellular region extracellular space extracellular space proteolysis peptidase activity serine-type peptidase activity positive regulation of cell population proliferation cell surface regulation of signaling receptor activity smooth muscle cell migration regulation of smooth muscle cell migration positive regulation of smooth muscle cell migration membrane hydrolase activity positive regulation of cell migration plasminogen activation plasminogen activation regulation of cell adhesion mediated by integrin regulation of cell adhesion mediated by integrin wound healing regulation of cell population proliferation fibrinolysis fibrinolysis skeletal muscle tissue regeneration positive regulation of ovulation neuron death regulation of smooth muscle cell-matrix adhesion regulation of hepatocyte proliferation positive regulation of reactive oxygen species metabolic process |
04610 |
| TC1400002746.mm.2 |
Gpr183 |
G protein-coupled receptor 183 |
14 |
-121952330 |
NM_183031, BC052868 NM_183031, BC052868 |
321019 |
50 |
adaptive immune response B cell activation involved in immune response mature B cell differentiation involved in immune response immune system process dendritic cell chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane humoral immune response signal transduction G protein-coupled receptor signaling pathway oxysterol binding oxysterol binding T cell chemotaxis membrane integral component of membrane osteoclast differentiation leukocyte chemotaxis leukocyte chemotaxis positive regulation of B cell proliferation positive regulation of B cell proliferation dendritic cell homeostasis cell chemotaxis T follicular helper cell differentiation positive regulation of ERK1 and ERK2 cascade regulation of astrocyte chemotaxis |
|
| TSUnmapped00000029.mm.2 |
Psd3 |
pleckstrin and Sec7 domain containing 3 |
8 |
-67689081, -67689081, -67689081 |
NM_177698 |
234353 |
22 |
guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse |
04144 |
| TC0600002233.mm.2 |
Tmem176b |
transmembrane protein 176B |
6 |
-48833810, -48833811, -48833811 |
NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 NM_001164207, NM_001164208, NM_001164209, NM_001286651, NM_001286652, NM_023056, NR_104575, BC019539, BC022166 |
65963 |
34 |
protein binding nucleus membrane integral component of membrane cell differentiation negative regulation of dendritic cell differentiation negative regulation of dendritic cell differentiation |
|
| TC1100001220.mm.2 |
Ccl7 |
chemokine (C-C motif) ligand 7 |
11 |
82045711 |
NM_013654, BC061126 NM_013654, BC061126 |
20306 |
80 |
monocyte chemotaxis cytokine activity extracellular region extracellular space extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity heparin binding neutrophil chemotaxis CCR2 chemokine receptor binding positive regulation of GTPase activity CCR chemokine receptor binding eosinophil chemotaxis lymphocyte chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to ethanol |
04060 04062 |
| TC0900001182.mm.2 |
Slc9a9 |
solute carrier family 9 (sodium/hydrogen exchanger), member 9 |
9 |
94669891 |
NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825 |
331004 |
22 |
endosome plasma membrane ion transport cation transport sodium ion transport regulation of pH antiporter activity solute:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity membrane integral component of membrane regulation of intracellular pH recycling endosome recycling endosome transmembrane transport potassium ion transmembrane transport sodium ion import across plasma membrane |
|
| TC1100000168.mm.2 |
Cnrip1 |
cannabinoid receptor interacting protein 1 |
11 |
17051858 |
NM_029861, BC087946 NM_029861, BC087946 |
380686 |
27 |
cytoplasm plasma membrane plasma membrane protein C-terminus binding regulation of signaling receptor activity type 1 cannabinoid receptor binding type 1 cannabinoid receptor binding myelin sheath negative regulation of signaling receptor activity negative regulation of signaling receptor activity |
|
| TC0200002532.mm.2 |
Ube2c |
ubiquitin-conjugating enzyme E2C |
2 |
164769928 |
NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033 |
68612 |
25 |
ubiquitin ligase complex nucleotide binding protein polyubiquitination ubiquitin-protein transferase activity ATP binding nucleus anaphase-promoting complex cytosol plasma membrane ubiquitin-dependent protein catabolic process cell cycle exit from mitosis free ubiquitin chain polymerization protein ubiquitination transferase activity regulation of mitotic metaphase/anaphase transition anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of exit from mitosis ubiquitin-like protein ligase binding cell division ubiquitin conjugating enzyme activity ubiquitin conjugating enzyme activity protein K48-linked ubiquitination protein K11-linked ubiquitination |
04120 |
| TC0200001045.mm.2 |
Itga6 |
integrin alpha 6 |
2 |
71786938 |
NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095 |
16403 |
274 |
integrin binding protein binding basement membrane plasma membrane plasma membrane adherens junction cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex external side of plasma membrane basal plasma membrane cell surface cell surface positive regulation of cell-substrate adhesion positive regulation of neuron projection development membrane integral component of membrane basolateral plasma membrane positive regulation of cell-cell adhesion hemidesmosome filopodium positive regulation of cell migration cell-substrate adhesion cellular response to extracellular stimulus insulin-like growth factor I binding cell adhesion mediated by integrin integrin alpha6-beta4 complex nail development neuregulin binding positive regulation of phosphorylation odontogenesis of dentin-containing tooth positive regulation of apoptotic process laminin binding positive regulation of GTPase activity skin morphogenesis protein-containing complex binding basal part of cell positive regulation of transcription by RNA polymerase II filopodium assembly metal ion binding brown fat cell differentiation leukocyte migration leukocyte migration cell-cell adhesion negative regulation of extrinsic apoptotic signaling pathway |
04510 04512 04514 04640 04810 05145 05200 05222 05410 05412 05414 |
| TC1900000216.mm.2 |
|
|
|
|
XM_986941 |
|
|
|
|
| TC0300001639.mm.2 |
Fabp4 |
fatty acid binding protein 4, adipocyte |
3 |
-10204342 |
NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426 |
11770 |
198 |
cytokine production long-chain fatty acid transporter activity fatty acid binding nucleus nucleoplasm cytoplasm cytosol negative regulation of protein kinase activity fatty acid metabolic process positive regulation of cell population proliferation lipid binding response to bacterium long-chain fatty acid transport long-chain fatty acid binding cholesterol homeostasis negative regulation of transcription, DNA-templated regulation of inflammatory response positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation hormone receptor binding cellular response to lithium ion cellular response to tumor necrosis factor positive regulation of cold-induced thermogenesis |
03320 |
| TC1500000031.mm.2 |
Dab2 |
disabled 2, mitogen-responsive phosphoprotein |
15 |
6386747, 6299788 |
NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 |
13132 |
118 |
negative regulation of transcription by RNA polymerase II cell morphogenesis involved in differentiation fibrillar center in utero embryonic development positive regulation of receptor recycling positive regulation of protein phosphorylation positive regulation of receptor internalization integrin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis pinocytosis apoptotic process activation of JUN kinase activity multicellular organism development endoderm development excretion protein C-terminus binding positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation negative regulation of neuron projection development protein transport membrane Wnt signaling pathway apical plasma membrane myeloid cell differentiation clathrin coat of coated pit clathrin-coated vesicle cell differentiation clathrin binding negative regulation of cell growth positive regulation of cell migration positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway clathrin-coated vesicle membrane cytoplasmic vesicle negative regulation of protein binding positive regulation of aldosterone biosynthetic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of transcription elongation from RNA polymerase II promoter leading edge cell differentiation phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity clathrin adaptor activity cargo receptor activity cargo receptor activity negative regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle positive regulation of cell adhesion positive regulation of cell adhesion positive regulation of endocytosis positive regulation of endocytosis positive regulation of transcription by RNA polymerase II SMAD binding clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm response to steroid hormone negative regulation of epithelial cell proliferation low-density lipoprotein particle receptor binding positive regulation of SMAD protein signal transduction negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of protein localization to plasma membrane negative regulation of protein localization to plasma membrane positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of Rho-dependent protein serine/threonine kinase activity positive regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of early endosome to late endosome transport positive regulation of aldosterone secretion positive regulation of integrin-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway |
04144 |
| TC0100003026.mm.2 |
Mcm6 |
minichromosome maintenance complex component 6 |
1 |
-128331574 |
NM_008567, BC050886, BC057584 NM_008567, BC050886, BC057584 NM_008567, BC050886, BC057584 |
17219 |
58 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation cell cycle hydrolase activity MCM complex MCM complex identical protein binding mitotic DNA replication single-stranded 3'-5' DNA helicase activity |
03030 04110 |
| TC1000000937.mm.2 |
Chst11 |
carbohydrate sulfotransferase 11 |
10 |
82985496 |
NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793 |
58250 |
35 |
N-acetylgalactosamine 4-O-sulfotransferase activity in utero embryonic development chondrocyte development Golgi apparatus carbohydrate metabolic process respiratory gaseous exchange by respiratory system sulfotransferase activity sulfotransferase activity post-embryonic development membrane integral component of membrane carbohydrate biosynthetic process transferase activity proteoglycan biosynthetic process chondroitin sulfate metabolic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process embryonic limb morphogenesis negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization post-anal tail morphogenesis regulation of cell population proliferation embryonic digit morphogenesis negative regulation of apoptotic process chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity cartilage development |
00532 00920 |
| TC1500000453.mm.2 |
Myc |
myelocytomatosis oncogene |
15 |
61985340 |
NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 |
17869 |
1226 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade re-entry into mitotic cell cycle chromatin euchromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding core promoter sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in ureteric bud morphogenesis B cell apoptotic process positive regulation of mesenchymal cell proliferation regulation of oxidative phosphorylation positive regulation of B cell apoptotic process DNA binding DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm spindle glucose metabolic process chromatin remodeling transcription, DNA-templated DNA-templated transcription, initiation regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II pyruvate transport amino acid transport cellular iron ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus inner mitochondrial membrane organization cell cycle arrest regulation of mitotic cell cycle transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage response to radiation response to radiation response to gamma radiation regulation of gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of mitochondrial membrane potential positive regulation of smooth muscle cell migration Wnt signaling pathway protein processing nuclear body transformation of host cell by virus axon ubiquitin protein ligase binding negative regulation of protein binding regulation of telomere maintenance protein-DNA complex disassembly protein-containing complex activating transcription factor binding cellular response to interferon-alpha cellular response to drug cellular response to drug skeletal muscle cell differentiation middle ear morphogenesis regulation of apoptotic process regulation of apoptotic process positive regulation of catalytic activity response to alkaloid positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of DNA binding pigmentation sequence-specific DNA binding canonical Wnt signaling pathway involved in negative regulation of apoptotic process canonical Wnt signaling pathway involved in positive regulation of apoptotic process protein-containing complex binding negative regulation of monocyte differentiation positive regulation of cell cycle positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of glucose import lactic acid secretion protein dimerization activity positive regulation of fibroblast proliferation negative regulation of fibroblast proliferation perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation skeletal system morphogenesis positive regulation of epithelial cell proliferation detection of mechanical stimulus involved in sensory perception of sound chromosome organization negative regulation of cell division positive regulation of telomerase activity positive regulation of glial cell proliferation positive regulation of transcription initiation from RNA polymerase II promoter negative regulation of cell death ERK1 and ERK2 cascade repressing transcription factor binding E-box binding cellular response to hypoxia positive regulation of metanephric cap mesenchymal cell proliferation positive regulation of cellular respiration positive regulation of oxidative phosphorylation regulation of somatic stem cell population maintenance positive regulation of DNA methylation positive regulation of DNA biosynthetic process positive regulation of response to DNA damage stimulus positive regulation of ATP biosynthetic process positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway |
04010 04012 04110 04310 04350 04630 05200 05210 05213 05216 05219 05220 05221 05222 |
| TC0500001734.mm.2 |
Daglb |
diacylglycerol lipase, beta |
5 |
143464492 |
NM_144915, BC016105 NM_144915, BC016105 |
231871 |
29 |
prostaglandin biosynthetic process triglyceride lipase activity nucleoplasm plasma membrane lipid metabolic process icosanoid metabolic process G protein-coupled glutamate receptor signaling pathway neuroblast proliferation positive regulation of triglyceride catabolic process membrane integral component of membrane lipid catabolic process lipase activity lipase activity hydrolase activity arachidonic acid metabolic process arachidonic acid metabolic process arachidonic acid metabolic process neurogenesis neurogenesis neurotransmitter biosynthetic process neurotransmitter biosynthetic process postsynaptic membrane metal ion binding regulation of inflammatory response endocannabinoid signaling pathway retrograde trans-synaptic signaling by endocannabinoid |
|
| TC0600002491.mm.2 |
Mat2a |
methionine adenosyltransferase II, alpha |
6 |
-72432795 |
NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360 |
232087 |
42 |
nucleotide binding methionine adenosyltransferase activity methionine adenosyltransferase activity methionine adenosyltransferase activity ATP binding cytosol cytosol S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to hormone amino acid binding transferase activity protein hexamerization response to drug identical protein binding metal ion binding methionine adenosyltransferase complex methionine adenosyltransferase complex protein heterooligomerization response to cAMP cellular response to leukemia inhibitory factor |
00270 01100 |
| TC1200001605.mm.2 |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
12 |
-32173396, -32173396 |
NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 |
30955 |
302 |
nucleotide binding angiogenesis regulation of protein phosphorylation immune system process positive regulation of acute inflammatory response sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex, class IA phosphatidylinositol 3-kinase complex, class IB phosphatidylinositol 3-kinase complex, class IB protein phosphorylation endocytosis chemotaxis inflammatory response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of endothelial cell migration positive regulation of endothelial cell migration negative regulation of triglyceride catabolic process phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling membrane membrane kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity phosphorylation cell migration transferase activity secretory granule localization 1-phosphatidylinositol-4-phosphate 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity positive regulation of Rac protein signal transduction positive regulation of Rac protein signal transduction phosphatidylinositol-3-phosphate biosynthetic process identical protein binding positive regulation of catalytic activity positive regulation of MAP kinase activity phosphatidylinositol phosphorylation phosphatidylinositol phosphorylation ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-mediated signaling positive regulation of protein kinase B signaling phosphatidylinositol kinase activity cellular response to cAMP hepatocyte apoptotic process regulation of calcium ion transmembrane transport negative regulation of fibroblast apoptotic process |
00562 04012 04062 04070 04150 04210 04370 04380 04510 04620 04630 04650 04660 04662 04664 04666 04670 04722 04810 04910 04914 04930 04960 04973 05100 05142 05145 05146 05160 05200 05210 05211 05212 05213 05214 05215 05218 05220 05221 05222 05223 |
| TC0100000476.mm.2 |
Cd28 |
CD28 antigen |
1 |
60746387 |
NM_007642, BC064058, CD28 NM_007642, BC064058, CD28 NM_007642, BC064058, CD28 |
12487 |
502 |
immunological synapse protease binding positive regulation of inflammatory response to antigenic stimulus plasma membrane immune response external side of plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression positive regulation of phosphatidylinositol 3-kinase signaling membrane integral component of membrane protein kinase binding T cell costimulation T cell costimulation T cell costimulation T cell costimulation T cell costimulation positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation T cell activation T cell activation regulation of T cell proliferation identical protein binding negative thymic T cell selection regulatory T cell differentiation membrane raft regulation of regulatory T cell differentiation positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation positive regulation of isotype switching to IgG isotypes T cell receptor signaling pathway T cell receptor signaling pathway positive regulation of protein kinase B signaling apoptotic signaling pathway protein complex involved in cell adhesion |
04514 04660 04672 04940 05320 05322 05323 05330 05332 05416 |
| TC0800002992.mm.2 |
Maf |
avian musculoaponeurotic fibrosarcoma oncogene homolog |
8 |
-115703252 |
NM_001025577 |
17132 |
182 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production lens development in camera-type eye DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II positive regulation of gene expression regulation of chondrocyte differentiation identical protein binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cell development inner ear development lens fiber cell differentiation lens fiber cell differentiation sequence-specific double-stranded DNA binding |
|
| TC0300000627.mm.2 |
Gask1b |
golgi associated kinase 1B |
3 |
79885929 |
NM_133187, BC056975 NM_133187, BC056975 |
68659 |
14 |
molecular_function Golgi apparatus biological_process membrane integral component of membrane |
|
| TC0600001433.mm.2 |
Cdca3 |
cell division cycle associated 3 |
6 |
124830175 |
NM_013538, BC002006 NM_013538, BC002006 |
14793 |
23 |
molecular_function cytoplasm adherens junction cell cycle cell division |
|
| TC1100004051.mm.2 |
Cd300lb |
CD300 molecule like family member B |
11 |
-114922778 |
NM_199221, CD300, BC160263 NM_199221, CD300, BC160263 NM_199221, CD300, BC160263 |
217304 |
21 |
immune system process neutrophil mediated immunity transmembrane signaling receptor activity protein binding plasma membrane membrane integral component of membrane positive regulation of mast cell activation cellular response to lipopolysaccharide |
|
| TC1100003561.mm.2 |
Abcc3 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
11 |
-94343294 |
NM_029600, BC150788 NM_029600, BC150788 |
76408 |
46 |
nucleotide binding ATP binding plasma membrane integral component of plasma membrane drug transmembrane transport ABC-type xenobiotic transporter activity glucuronoside transmembrane transporter activity ABC-type glutathione S-conjugate transporter activity ABC-type bile acid transporter activity bile acid and bile salt transport canalicular bile acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane ATPase activity transmembrane transporter activity ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transport xenobiotic transmembrane transporter activity transmembrane transport transmembrane transport icosanoid transmembrane transporter activity leukotriene transport anion transmembrane transport |
02010 04976 |
| TC1400001676.mm.2 |
Sh3bp5 |
SH3-domain binding protein 5 (BTK-associated) |
14 |
-31372613, -31372613 |
NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741 |
24056 |
27 |
protein kinase inhibitor activity protein kinase inhibitor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytoplasm mitochondrion negative regulation of protein kinase activity membrane nuclear body SH3 domain binding cytoplasmic vesicle membrane cytoplasmic vesicle intracellular signal transduction intracellular signal transduction negative regulation of protein tyrosine kinase activity |
|
| TC0600002404.mm.2 |
Hpgds |
hematopoietic prostaglandin D synthase |
6 |
-65117292 |
NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737 |
54486 |
47 |
magnesium ion binding prostaglandin biosynthetic process glutathione transferase activity glutathione transferase activity prostaglandin-D synthase activity prostaglandin-D synthase activity calcium ion binding nucleoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process prostaglandin metabolic process glutathione metabolic process transferase activity isomerase activity protein homodimerization activity intracellular membrane-bounded organelle negative regulation of male germ cell proliferation |
00590 01100 |
| TC0700004624.mm.2 |
Plk1 |
polo like kinase 1 |
7 |
122159434 |
NM_011121, BC006880 NM_011121, BC006880 |
18817 |
147 |
mitotic sister chromatid segregation G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II establishment of mitotic spindle orientation nucleotide binding mitotic cell cycle mitotic cell cycle mitotic cytokinesis magnesium ion binding chromosome, centromeric region kinetochore kinetochore condensed chromosome, centromeric region chromatin synaptonemal complex spindle pole spindle pole condensed nuclear chromosome outer kinetochore microtubule bundle formation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus chromosome cytoplasm cytoplasm centrosome centrosome centriole spindle cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation cell cycle mitotic spindle assembly checkpoint centrosome cycle regulation of mitotic cell cycle microtubule binding positive regulation of peptidyl-threonine phosphorylation anaphase-promoting complex binding microtubule cytoskeleton kinase activity phosphorylation female meiosis chromosome segregation protein ubiquitination transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding regulation of mitotic metaphase/anaphase transition midbody protein destabilization positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis regulation of cytokinesis protein localization to organelle centriolar satellite polar body extrusion after meiotic divisions identical protein binding negative regulation of apoptotic process regulation of protein binding regulation of protein binding homologous chromosome segregation establishment of protein localization negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of proteolysis nuclear envelope disassembly spindle midzone cell division positive regulation of ubiquitin-protein transferase activity synaptonemal complex disassembly protein localization to chromatin signal transduction involved in G2 DNA damage checkpoint protein localization to nuclear envelope mitotic spindle pole regulation of mitotic spindle assembly positive regulation of ubiquitin protein ligase activity regulation of protein localization to cell cortex |
04110 04114 04914 |
| TC0400003366.mm.2 |
Kif2c |
kinesin family member 2C |
4 |
-117159632, -117159635 |
NM_134471, BC006841 NM_134471, BC006841 |
73804 |
32 |
nucleotide binding chromosome, centromeric region chromosome, centromeric region kinetochore microtubule motor activity ATP binding nucleus chromosome cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule depolymerization cell cycle chromosome segregation mitotic metaphase plate congression microtubule binding microtubule cytoskeleton ATPase activity establishment or maintenance of microtubule cytoskeleton polarity microtubule plus-end microtubule plus-end binding cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore regulation of chromosome segregation |
|
| TC1100001219.mm.2 |
Ccl2 |
chemokine (C-C motif) ligand 2 |
11 |
82035576 |
NM_011333, BC145867, BC145869 NM_011333, BC145867, BC145869 NM_011333, BC145867, BC145869 |
20296 |
908 |
angiogenesis G protein-coupled receptor binding positive regulation of leukocyte mediated cytotoxicity positive regulation of endothelial cell proliferation leukocyte migration involved in inflammatory response monocyte chemotaxis positive regulation of leukocyte migration positive regulation of cellular extravasation cytokine activity protein binding extracellular region extracellular space extracellular space extracellular space extracellular space cytoplasm rough endoplasmic reticulum cellular calcium ion homeostasis chemotaxis inflammatory response immune response cytoskeleton organization transforming growth factor beta receptor signaling pathway G protein-coupled receptor signaling pathway chemokine activity chemokine activity heparin binding glial cell migration regulation of cell shape response to heat response to wounding response to bacterium regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of macrophage chemotaxis positive regulation of macrophage chemotaxis negative regulation of angiogenesis cytokine-mediated signaling pathway sensory perception of pain positive regulation of cell-cell adhesion endocytic vesicle dendrite neutrophil chemotaxis neutrophil chemotaxis killing of cells of other organism CCR2 chemokine receptor binding positive regulation of tumor necrosis factor production positive regulation of collagen biosynthetic process helper T cell extravasation monocyte homeostasis neuronal cell body perikaryon positive regulation of GTPase activity axon terminus C-fiber synapse positive regulation of cell adhesion vascular endothelial growth factor receptor signaling pathway CCR chemokine receptor binding eosinophil chemotaxis eosinophil chemotaxis macrophage chemotaxis lymphocyte chemotaxis lymphocyte chemotaxis perinuclear region of cytoplasm positive regulation of synaptic transmission positive regulation of T cell activation positive regulation of nitric-oxide synthase biosynthetic process positive regulation of synaptic transmission, glutamatergic antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to interferon-gamma cellular response to interferon-gamma cellular response to interleukin-1 cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to tumor necrosis factor positive regulation of monocyte chemotaxis positive regulation of monocyte chemotaxis positive regulation of immune complex clearance by monocytes and macrophages positive regulation of wound healing positive regulation of protein targeting to membrane positive regulation of NMDA glutamate receptor activity positive regulation of apoptotic cell clearance |
04062 |
| TC1300001814.mm.2 |
F13a1 |
coagulation factor XIII, A1 subunit |
13 |
-36867177, -36867177 |
NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274 |
74145 |
69 |
protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity extracellular region cytoplasm blood coagulation blood coagulation hemostasis transferase activity transferase activity, transferring acyl groups peptide cross-linking peptide cross-linking peptide cross-linking metal ion binding collagen-containing extracellular matrix blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation |
04610 |
| TC1100004053.mm.2 |
Cd300ld |
CD300 molecule like family member d |
11 |
-114982445 |
NM_145437, BC019814, CD300-like NM_145437, BC019814, CD300-like NM_145437, BC019814, CD300-like |
217305 |
16 |
virus receptor activity immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane membrane integral component of membrane regulation of interleukin-6 production regulation of tumor necrosis factor production |
|
| TC1900001095.mm.2 |
Fads2 |
fatty acid desaturase 2 |
19 |
-10062764 |
NM_019699, BC057189 NM_019699, BC057189 |
56473 |
39 |
stearoyl-CoA 9-desaturase activity endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane linoleoyl-CoA desaturase activity oxidoreductase activity |
00592 01040 03320 |
| TC1500001963.mm.2 |
Nfam1 |
Nfat activating molecule with ITAM motif 1 |
15 |
-82996735, -82996735, -82996735 |
NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 NM_001271411, NM_001271412, NM_001271413, NM_001271414, NM_028728, BC150488 |
74039 |
14 |
positive regulation of cytokine production transmembrane signaling receptor activity transmembrane signaling receptor activity transmembrane signaling receptor activity plasma membrane signal transduction signal transduction cell surface membrane integral component of membrane integral component of membrane integral component of membrane B cell differentiation intracellular signal transduction intracellular signal transduction membrane raft membrane raft regulation of B cell differentiation B cell receptor signaling pathway B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity positive regulation of DNA-binding transcription factor activity |
|
| TC1800000291.mm.2 |
Kif20a |
kinesin family member 20A |
18 |
34624935, 34624623, 34625032 |
NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 |
19348 |
33 |
nucleotide binding mitotic cytokinesis microtubule bundle formation microtubule motor activity ATP binding nucleus nucleoplasm cytoplasm Golgi apparatus spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding protein transport ATPase activity protein kinase binding midbody cleavage furrow regulation of cytokinesis intercellular bridge midbody abscission |
|
| TC0800000937.mm.2 |
Asf1b |
anti-silencing function 1B histone chaperone |
8 |
83955693 |
NM_024184, BC003428 NM_024184, BC003428 |
66929 |
23 |
chromatin chromatin blastocyst hatching nucleus nucleoplasm chromatin organization chromatin assembly or disassembly nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly DNA replication-independent nucleosome assembly protein-containing complex histone binding histone binding |
|
| TC1400000322.mm.2 |
Nt5dc2 |
5'-nucleotidase domain containing 2 |
14 |
31134735, 31131088 |
NM_027289, BC011230 NM_027289, BC011230 |
70021 |
17 |
cellular_component 5'-nucleotidase activity |
|
| TC0100002285.mm.2 |
Slc40a1 |
solute carrier family 40 (iron-regulated transporter), member 1 |
1 |
-45908069 |
NM_016917, BC003438 NM_016917, BC003438 |
53945 |
138 |
lymphocyte homeostasis endothelium development iron ion transmembrane transporter activity iron ion transmembrane transporter activity iron ion transmembrane transporter activity protein binding nucleoplasm cytosol plasma membrane plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle ferrous iron transmembrane transporter activity membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane peptide hormone binding peptide hormone binding peptide hormone binding regulation of transcription from RNA polymerase II promoter in response to iron iron ion transmembrane transport iron ion transmembrane transport iron ion transmembrane transport identical protein binding negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II spleen development iron ion homeostasis iron ion homeostasis spleen trabecula formation multicellular organismal iron ion homeostasis iron ion export across plasma membrane |
|
| TC1100004229.mm.2 |
Cbr2 |
carbonyl reductase 2 |
11 |
-120729484 |
NM_007621, BC010758 NM_007621, BC010758 |
12409 |
25 |
carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity protein binding mitochondrion xylulose metabolic process glucose metabolic process NADH oxidation oxidoreductase activity identical protein binding protein self-association L-xylulose reductase (NADP+) activity |
00590 01100 |
| TC0800000096.mm.2 |
Arhgef7 |
Rho guanine nucleotide exchange factor (GEF7) |
8 |
11758364, 11728057, 11779283, 11728057, 11758364 |
NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 |
54126 |
81 |
storage vacuole hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane focal adhesion Golgi organization small GTPase mediated signal transduction nervous system development protein kinase binding protein kinase binding lamellipodium lamellipodium assembly cell junction growth cone small GTPase binding positive regulation of protein binding protein-containing complex regulation of Rho protein signal transduction intracellular signal transduction cell projection neuron projection neuronal cell body positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of GTPase activity positive regulation of GTPase activity astrocyte cell migration positive regulation of growth hormone secretion postsynaptic actin cytoskeleton organization GABA-ergic synapse presynaptic actin cytoskeleton organization regulation of GTP binding |
04810 |
| TC0100003029.mm.2 |
Cxcr4 |
chemokine (C-X-C motif) receptor 4 |
1 |
-128588198 |
NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322 |
12767 |
580 |
branching involved in blood vessel morphogenesis ameboidal-type cell migration neuron migration neuron migration kidney development positive regulation of protein phosphorylation epithelial cell development ventricular septum development actin binding G protein-coupled receptor activity chemokine receptor activity protein binding nucleus cytoplasm lysosome endosome early endosome late endosome plasma membrane plasma membrane cell-cell junction chemotaxis immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration germ cell development nervous system development brain development brain development motor neuron axon guidance germ cell migration animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface cell surface membrane integral component of membrane cell migration C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling cytokine binding C-C chemokine binding C-C chemokine binding neurogenesis neurogenesis telencephalon cell migration cell junction regulation of cell adhesion regulation of cell migration regulation of cell migration positive regulation of cell migration growth cone cell leading edge cytoplasmic vesicle ubiquitin protein ligase binding myosin light chain binding protein-containing complex positive regulation of vascular wound healing hematopoietic stem cell migration aorta development C-X-C motif chemokine 12 receptor activity CXCL12-activated CXCR4 signaling pathway T cell proliferation identical protein binding regulation of programmed cell death ubiquitin binding myelin maintenance endothelial cell differentiation generation of neurons positive regulation of oligodendrocyte differentiation positive regulation of neurogenesis regulation of viral process regulation of chemotaxis positive regulation of chemotaxis detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain regulation of calcium ion transport cardiac muscle contraction cell chemotaxis endothelial tube morphogenesis neural precursor cell proliferation positive regulation of ERK1 and ERK2 cascade cellular response to cytokine stimulus cellular response to cytokine stimulus positive regulation of calcium ion import positive regulation of cold-induced thermogenesis positive regulation of dendrite extension positive regulation of mesenchymal stem cell migration positive regulation of macrophage migration inhibitory factor signaling pathway |
04060 04062 04144 04360 04670 04672 |
| TC0800001247.mm.2 |
Prmt7 |
protein arginine N-methyltransferase 7 |
8 |
106211053 |
NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177 |
214572 |
42 |
spliceosomal snRNP assembly fibrillar center protein binding nucleus nucleoplasm cytoplasm cytosol chromatin organization regulation of gene expression by genetic imprinting protein methylation methyltransferase activity histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity [myelin basic protein]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation cell differentiation methylation histone arginine methylation protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity ribonucleoprotein complex binding DNA methylation involved in gamete generation histone methyltransferase activity (H4-R3 specific) |
|
| TC1500000175.mm.2 |
|
|
|
|
NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379 |
|
|
inorganic phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity plasma membrane integral component of plasma membrane integral component of plasma membrane phosphate ion transport phosphate ion transmembrane transporter activity membrane integral component of membrane integral component of membrane regulation of bone mineralization inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity phosphate ion transmembrane transport |
|
| TC0900000051.mm.2 |
Mmp27 |
matrix metallopeptidase 27 |
9 |
7571395 |
NM_001030289 |
234911 |
12 |
metalloendopeptidase activity extracellular matrix organization collagen catabolic process extrinsic component of endoplasmic reticulum membrane |
|
| TC0100003210.mm.2 |
Rgs18 |
regulator of G-protein signaling 18 |
1 |
-144752682 |
NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 |
64214 |
21 |
GTPase activator activity cytoplasm G protein-coupled receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction |
|
| TC0200000603.mm.2 |
Angptl2 |
angiopoietin-like 2 |
2 |
33215960 |
NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610 |
26360 |
53 |
angiogenesis signaling receptor binding extracellular region extracellular space extracellular space collagen-containing extracellular matrix |
|
| TC0900001173.mm.2 |
Plscr4 |
phospholipid scramblase 4 |
9 |
92457377 |
NM_178711, BC052067 NM_178711, BC052067 |
235527 |
14 |
plasma membrane plasma membrane membrane integral component of membrane plasma membrane phospholipid scrambling phospholipid scramblase activity enzyme binding CD4 receptor binding cellular response to lipopolysaccharide |
|
| TC1100004057.mm.2 |
|
|
|
|
NM_001101656, NM_001101657, BC119352 NM_001101656, NM_001101657, BC119352 NM_001101656, NM_001101657, BC119352 |
|
|
immune system process molecular_function transmembrane signaling receptor activity protein binding cellular_component lysosome endosome plasma membrane biological_process membrane integral component of membrane positive regulation of protein ubiquitination positive regulation of toll-like receptor 9 signaling pathway positive regulation of toll-like receptor 9 signaling pathway |
|
| TC0300001378.mm.2 |
Slc39a8 |
solute carrier family 39 (metal ion transporter), member 8 |
3 |
135825789, 135825656, 135825278 |
NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 |
67547 |
51 |
iron ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity lysosome lysosomal membrane plasma membrane plasma membrane integral component of plasma membrane transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated protein N-linked glycosylation arginine metabolic process ion transport cobalt ion transport zinc ion transport cellular cadmium ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cobalt ion transmembrane transporter activity bicarbonate transmembrane transporter activity anion:cation symporter activity bicarbonate transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane metal ion transport cellular manganese ion homeostasis extracellular matrix organization extracellular matrix organization organelle membrane regulation of membrane potential metal ion transmembrane transporter activity transmembrane transport leukocyte adhesion to arterial endothelial cell cadmium ion transmembrane transport cadmium ion transmembrane transport cadmium ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport zinc ion transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane selenite:proton symporter activity plasma membrane selenite transport plasma membrane selenite transport iron ion import across plasma membrane iron ion import across plasma membrane zinc:bicarbonate symporter activity cartilage homeostasis mitochondrial manganese ion transmembrane transport |
|
| TC0800000846.mm.2 |
Mcm5 |
minichromosome maintenance complex component 5 |
8 |
75109508 |
NM_008566, BC094416 NM_008566, BC094416 |
17218 |
41 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleoplasm chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation cell cycle hydrolase activity single-stranded DNA helicase activity MCM complex MCM complex 3'-5' DNA helicase activity |
03030 04110 |
| TC0900001673.mm.2 |
Ccr3 |
chemokine (C-C motif) receptor 3 |
9 |
124021970 |
NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968 |
12771 |
76 |
positive regulation of endothelial cell proliferation mast cell chemotaxis G protein-coupled receptor activity chemokine receptor activity protein binding extracellular space cytoplasm endosome plasma membrane chemotaxis inflammatory response immune response signal transduction positive regulation of cytosolic calcium ion concentration external side of plasma membrane membrane integral component of membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding C-C chemokine binding C-C chemokine binding angioblast cell migration positive regulation of angiogenesis positive regulation of angiogenesis eosinophil chemotaxis cell chemotaxis ERK1 and ERK2 cascade |
04060 04062 |
| TC0600002690.mm.2 |
Mcm2 |
minichromosome maintenance complex component 2 |
6 |
-88883473 |
NM_008564, BC055318 NM_008564, BC055318 |
17216 |
82 |
nucleotide binding double-strand break repair via break-induced replication chromatin DNA binding DNA replication origin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm nuclear origin of replication recognition complex chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA replication initiation nucleosome assembly apoptotic process cell cycle hydrolase activity single-stranded DNA helicase activity enzyme binding histone binding MCM complex MCM complex 3'-5' DNA helicase activity metal ion binding cellular response to interleukin-4 cochlea development mitotic DNA replication initiation negative regulation of DNA helicase activity |
03030 04110 |
| TC1600000650.mm.2 |
Naa50 |
N(alpha)-acetyltransferase 50, NatE catalytic subunit |
16 |
44139808, 44139790 |
NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 |
72117 |
26 |
peptide alpha-N-acetyltransferase activity protein binding nucleus cytoplasm cytoplasm cytoplasm cytosol N-terminal protein amino acid acetylation N-terminal protein amino acid acetylation mitotic sister chromatid cohesion N-acetyltransferase activity H4 histone acetyltransferase activity histone acetylation transferase activity transferase activity, transferring acyl groups NatA complex NatA complex establishment of mitotic sister chromatid cohesion peptidyl-lysine acetyltransferase activity mitotic sister chromatid cohesion, centromeric |
|
| TC1100001256.mm.2 |
Ccl4 |
chemokine (C-C motif) ligand 4 |
11 |
83662583 |
NM_013652, BC119257, BC119259 NM_013652, BC119257, BC119259 NM_013652, BC119257, BC119259 |
20303 |
86 |
monocyte chemotaxis cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis inflammatory response inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity chemokine activity response to toxic substance neutrophil chemotaxis leukocyte chemotaxis CCR1 chemokine receptor binding CCR5 chemokine receptor binding positive regulation of tumor necrosis factor production cellular response to drug identical protein binding positive regulation of vascular permeability positive regulation of GTPase activity negative regulation by host of viral transcription CCR chemokine receptor binding eosinophil chemotaxis lymphocyte chemotaxis positive regulation of calcium-mediated signaling positive regulation of calcium ion transport chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor positive regulation of natural killer cell chemotaxis |
04060 04062 04620 04623 |
| TC1000001207.mm.2 |
Dusp6 |
dual specificity phosphatase 6 |
10 |
99263230 |
NM_026268, BC003869 NM_026268, BC003869 |
67603 |
165 |
inactivation of MAPK activity inactivation of MAPK activity negative regulation of protein phosphorylation phosphoprotein phosphatase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding nucleoplasm cytoplasm cytoplasm cytosol cytosol protein dephosphorylation protein dephosphorylation protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity positive regulation of cell death dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-threonine dephosphorylation positive regulation of apoptotic process positive regulation of apoptotic process mitogen-activated protein kinase binding regulation of heart growth regulation of heart growth negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade |
04010 |
| TC1300001558.mm.2 |
H2ac15 |
H2A clustered histone 15 |
13 |
-21753376 |
NM_178183, BC119335 NM_178183, BC119335 |
319169 |
7 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC1600001011.mm.2 |
Itsn1 |
intersectin 1 (SH3 domain protein 1A) |
16 |
91729370, 91729370, 91729370 |
NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 |
16443 |
71 |
guanyl-nucleotide exchange factor activity calcium ion binding protein binding nucleus nuclear envelope cytoplasm cytoplasm endosome cytosol plasma membrane plasma membrane clathrin-coated pit clathrin-coated pit clathrin-coated pit exocytosis endocytosis small GTPase mediated signal transduction protein transport membrane endosomal transport kinase activator activity lamellipodium cell junction endocytic vesicle cytoplasmic vesicle cellular protein localization regulation of Rho protein signal transduction intracellular signal transduction presynaptic membrane cell projection neuron projection neuronal cell body dendritic spine negative regulation of neuron apoptotic process calyx of Held synapse metal ion binding synaptic vesicle endocytosis synaptic vesicle endocytosis positive regulation of protein kinase B signaling molecular adaptor activity molecular adaptor activity positive regulation of growth hormone secretion positive regulation of dendritic spine development proline-rich region binding apical dendrite intracellular vesicle intracellular vesicle presynaptic endocytic zone postsynaptic actin cytoskeleton glutamatergic synapse clathrin-dependent synaptic vesicle endocytosis regulation of modification of postsynaptic actin cytoskeleton positive regulation of caveolin-mediated endocytosis |
|
| TC1100002224.mm.2 |
Fignl1 |
fidgetin-like 1 |
11 |
-11800287 |
NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 |
60530 |
23 |
nucleotide binding nuclear chromosome osteoblast differentiation ATP binding nucleus nucleus cytoplasm male meiotic nuclear division microtubule-severing ATPase activity regulation of double-strand break repair via homologous recombination hydrolase activity ATPase activity cytoplasmic microtubule organization osteoblast proliferation negative regulation of apoptotic process metal ion binding perinuclear region of cytoplasm regulation of cell cycle cellular response to ionizing radiation negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0800000126.mm.2 |
Tfdp1 |
transcription factor Dp 1 |
8 |
13338803, 13338750 |
NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 |
21781 |
62 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II cell cycle transcription factor binding epidermis development protein domain specific binding anoikis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of DNA-binding transcription factor activity regulation of cell cycle negative regulation of fat cell proliferation RNA polymerase II transcription regulator complex positive regulation of G1/S transition of mitotic cell cycle regulation of DNA biosynthetic process |
04110 04350 |
| TC1500001940.mm.2 |
Cenpm |
centromere protein M |
15 |
-82233775, -82233775 |
NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 |
66570 |
19 |
chromosome, centromeric region kinetochore molecular_function nucleus chromosome cytoplasm cytosol biological_process |
|
| TC0500000052.mm.2 |
Abcb1b |
ATP-binding cassette, sub-family B (MDR/TAP), member 1B |
5 |
8798146 |
NM_011075, BC141363, BC150811 NM_011075, BC141363, BC150811 NM_011075, BC141363, BC150811 |
18669 |
256 |
Golgi membrane nucleotide binding ATP binding mitochondrion plasma membrane establishment of endothelial blood-brain barrier membrane integral component of membrane apical plasma membrane ATPase activity response to drug ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity phospholipid translocation intercellular canaliculus transmembrane transport Sertoli cell barrier remodeling phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity external side of apical plasma membrane ceramide floppase activity ceramide translocation |
02010 04976 |
| TC1300000246.mm.2 |
H3c8 |
H3 clustered histone 8 |
13 |
23535417 |
NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357 |
97908 |
28 |
nuclear chromosome nucleosome nucleus nucleoplasm nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1000003119.mm.2 |
Lrp1 |
low density lipoprotein receptor-related protein 1 |
10 |
-127538157 |
NM_008512 |
16971 |
324 |
protease binding astrocyte activation involved in immune response cardiac septum development calcium ion binding protein binding nucleus cytoplasm endosome early endosome Golgi apparatus cytoskeleton plasma membrane integral component of plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis phagocytosis lysosomal transport positive regulation of cytosolic calcium ion concentration protein kinase C-activating G protein-coupled receptor signaling pathway multicellular organism development cholesterol metabolic process cell population proliferation external side of plasma membrane negative regulation of cell-substrate adhesion positive regulation of cholesterol efflux positive regulation of cell death positive regulation of neuron projection development negative regulation of neuron projection development negative regulation of smooth muscle cell migration coreceptor activity membrane integral component of membrane basolateral plasma membrane alpha-2 macroglobulin receptor activity cell junction clathrin-coated vesicle negative regulation of Wnt signaling pathway dendrite clathrin heavy chain binding positive regulation of protein binding positive regulation of lipid transport regulation of cholesterol transport regulation of phospholipase A2 activity insulin-responsive compartment regulation of actin cytoskeleton organization apolipoprotein binding positive regulation of insulin secretion involved in cellular response to glucose stimulus aorta morphogenesis cargo receptor activity cargo receptor activity neuronal cell body negative regulation of apoptotic process receptor complex apoptotic cell clearance negative regulation of neuron apoptotic process cellular lipid catabolic process axonal growth cone protein-containing complex binding apical part of cell synapse positive regulation of axon extension positive regulation of endocytosis metal ion binding perinuclear region of cytoplasm positive regulation of axon extension involved in regeneration positive regulation of collateral sprouting of injured axon positive regulation of phagocytosis positive regulation of protein transport negative regulation of cytosolic calcium ion concentration negative regulation of focal adhesion assembly negative regulation of cell death coronary vasculature development chemoattraction of axon positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process transport across blood-brain barrier positive regulation of Schwann cell migration positive regulation of amyloid-beta clearance positive regulation of protein localization to plasma membrane positive regulation of cholesterol import positive regulation of transcytosis cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell migration positive regulation of lysosomal protein catabolic process positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of platelet-derived growth factor receptor-beta signaling pathway |
05010 05144 |
| TC0200001748.mm.2 |
Knstrn |
kinetochore-localized astrin/SPAG5 binding |
2 |
118814002 |
NM_026412, BC031709 NM_026412, BC031709 |
51944 |
22 |
mitotic sister chromatid segregation mitotic sister chromatid segregation microtubule cytoskeleton organization chromosome, centromeric region kinetochore kinetochore ruffle protein binding nucleus chromosome cytoplasm cytoskeleton microtubule plasma membrane cell cycle spindle organization spindle organization chromosome segregation cell migration centriolar satellite centriolar satellite microtubule plus-end microtubule plus-end protein homodimerization activity microtubule plus-end binding cell division regulation of attachment of spindle microtubules to kinetochore regulation of attachment of spindle microtubules to kinetochore cellular response to epidermal growth factor stimulus mitotic spindle mitotic spindle |
|
| TC0600001443.mm.2 |
Lpar5 |
lysophosphatidic acid receptor 5 |
6 |
125067919, 125071334 |
NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 |
381810 |
39 |
G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane positive regulation of CREB transcription factor activity positive regulation of CREB transcription factor activity behavioral response to pain behavioral response to pain |
|
| TC0300000934.mm.2 |
H3c13 |
H3 clustered histone 13 |
3 |
96268653 |
NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 |
319154 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC0200000245.mm.2 |
Mrc1 |
mannose receptor, C type 1 |
2 |
14229413 |
NM_008625, BC141338 NM_008625, BC141338 |
17533 |
108 |
transmembrane signaling receptor activity protein binding mannose binding endosome plasma membrane plasma membrane plasma membrane endocytosis receptor-mediated endocytosis receptor-mediated endocytosis cell surface endosome membrane membrane integral component of membrane carbohydrate binding signaling receptor activity cargo receptor activity cellular response to lipopolysaccharide cellular response to interferon-gamma cellular response to interleukin-4 |
04145 |
| TC0900002593.mm.2 |
Ccnb2 |
cyclin B2 |
9 |
-70407688 |
NM_007630, BC008247 NM_007630, BC008247 |
12442 |
54 |
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex in utero embryonic development protein binding nucleus cytoplasm cytoplasm centrosome centrosome cytosol cell cycle spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I G2/MI transition of meiotic cell cycle G2/MI transition of meiotic cell cycle microtubule cytoskeleton membrane cyclin-dependent protein serine/threonine kinase regulator activity regulation of growth T cell homeostasis mitotic cell cycle phase transition thymus development cell division |
04110 04114 04115 04914 |
| TC0700002422.mm.2 |
C5ar1 |
complement component 5a receptor 1 |
7 |
-16246742, -16246744 |
NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643 NM_001173550, NM_007577, BC125641, BC125643 |
12273 |
256 |
microglial cell activation complement component C5a binding complement receptor mediated signaling pathway complement receptor activity complement component C5a receptor activity complement component C5a receptor activity complement component C5a receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane apoptotic process chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell surface positive regulation of vascular endothelial growth factor production positive regulation of macrophage chemotaxis membrane integral component of membrane basolateral plasma membrane cell proliferation in hindbrain neutrophil chemotaxis cytoplasmic vesicle response to peptidoglycan complement component C5a signaling pathway mRNA transcription by RNA polymerase II negative regulation of neuron apoptotic process apical part of cell positive regulation of angiogenesis astrocyte activation positive regulation of epithelial cell proliferation defense response to Gram-positive bacterium cognition positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis amyloid-beta clearance presynapse organization regulation of tau-protein kinase activity |
04080 04610 05150 |
| TC1300000262.mm.2 |
H1f1 |
H1.1 linker histone, cluster member |
13 |
23763667 |
NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850 |
80838 |
42 |
nucleosome DNA binding double-stranded DNA binding protein binding nucleus nucleus chromosome nucleosome assembly spermatogenesis spermatogenesis heparin binding cell surface nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing vesicle negative regulation of DNA recombination positive regulation of receptor-mediated endocytosis |
|
| TC1300002037.mm.2 |
Cltb |
clathrin, light polypeptide (Lcb) |
13 |
-54592385 |
NM_028870, BC070404 NM_028870, BC070404 |
74325 |
32 |
structural molecule activity trans-Golgi network cytosol plasma membrane plasma membrane plasma membrane clathrin-coated pit intracellular protein transport membrane vesicle-mediated transport clathrin coat clathrin vesicle coat clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle clathrin heavy chain binding peptide binding intracellular membrane-bounded organelle clathrin coat assembly ciliary membrane clathrin-dependent endocytosis presynaptic endocytic zone membrane postsynaptic endocytic zone cytoplasmic component |
04142 04144 05016 05100 |
| TC1000001066.mm.2 |
Igf1 |
insulin-like growth factor 1 |
10 |
87861110, 87859051, 87858264 |
NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 NM_001111274, NM_001111275, NM_001111276, NM_010512, BC012409, NM_184052 |
16000 |
992 |
activation of MAPK activity osteoblast differentiation cell activation regulation of protein phosphorylation blood vessel remodeling blood vessel remodeling negative regulation of immune system process insulin receptor binding insulin receptor binding insulin-like growth factor receptor binding insulin-like growth factor receptor binding integrin binding hormone activity steroid binding protein binding extracellular region interstitial matrix extracellular space extracellular space extracellular space cytoplasm plasma membrane regulation of translation nervous system development sensory perception of smell memory circadian rhythm growth factor activity cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation response to heat glial cell differentiation regulation of gene expression positive regulation of glycoprotein biosynthetic process positive regulation of cardiac muscle hypertrophy positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression negative regulation of muscle cell apoptotic process phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration muscle hypertrophy myotube cell development positive regulation of smooth muscle cell migration positive regulation of cerebellar granule cell precursor proliferation water homeostasis proteoglycan biosynthetic process positive regulation of cell growth lung development positive regulation of cell migration mammary gland development exocrine pancreas development platelet alpha granule positive regulation of myelination activation of protein kinase B activity negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production regulation of establishment or maintenance of cell polarity regulation of intracellular steroid hormone receptor signaling pathway negative regulation of smooth muscle cell apoptotic process multicellular organism growth bone mineralization involved in bone maturation alphav-beta3 integrin-IGF-1-IGF1R complex wound healing positive regulation of activated T cell proliferation regulation of cell population proliferation positive regulation of tyrosine phosphorylation of STAT protein insulin-like growth factor ternary complex insulin-like growth factor ternary complex neuronal cell body negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of DNA binding positive regulation of MAPK cascade protein kinase B signaling positive regulation of blood vessel endothelial cell migration protein serine/threonine kinase activator activity positive regulation of insulin-like growth factor receptor signaling pathway regulation of nitric oxide biosynthetic process myoblast differentiation response to ethanol positive regulation of fat cell differentiation positive regulation of osteoblast differentiation positive regulation of glycogen biosynthetic process positive regulation of glycolytic process positive regulation of mitotic nuclear division positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of glucose import positive regulation of Ras protein signal transduction insulin-like growth factor receptor signaling pathway insulin-like growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of fibroblast proliferation lung alveolus development lung alveolus development cell development positive regulation of smooth muscle cell proliferation branching morphogenesis of an epithelial tube inner ear development chondroitin sulfate proteoglycan biosynthetic process positive regulation of epithelial cell proliferation positive regulation of protein secretion positive regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation protein stabilization detection of mechanical stimulus involved in sensory perception regulation of protein metabolic process myoblast proliferation positive regulation of protein kinase B signaling regulation of calcium ion transport positive regulation of glial cell proliferation negative regulation of oocyte development lung vasculature development lung vasculature development lung lobe morphogenesis lung lobe morphogenesis type I pneumocyte differentiation type II pneumocyte differentiation prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis prostate gland growth prostate gland growth prostate gland epithelium morphogenesis prostate gland stromal morphogenesis negative regulation of androgen receptor signaling pathway positive regulation of cell growth involved in cardiac muscle cell development ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade exocytic vesicle positive regulation of calcineurin-NFAT signaling cascade cellular response to glucose stimulus positive regulation of protein serine/threonine kinase activity positive regulation of steroid hormone biosynthetic process negative regulation of release of cytochrome c from mitochondria extrinsic apoptotic signaling pathway in absence of ligand negative regulation of neuroinflammatory response negative regulation of oligodendrocyte apoptotic process negative regulation of neuron death negative regulation of amyloid-beta formation positive regulation of trophectodermal cell proliferation negative regulation of cholangiocyte apoptotic process cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process positive regulation of vascular endothelial cell proliferation cellular response to insulin-like growth factor stimulus positive regulation of myoblast proliferation positive regulation of transcription regulatory region DNA binding negative regulation of extrinsic apoptotic signaling pathway |
04114 04115 04150 04510 04730 04914 04960 05200 05214 05215 05218 05410 05414 |
| TC0100001985.mm.2 |
Eya1 |
EYA transcriptional coactivator and phosphatase 1 |
1 |
-14168957 |
NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 |
14048 |
151 |
establishment of mitotic spindle orientation establishment of mitotic spindle orientation metanephros development ureteric bud development branching involved in ureteric bud morphogenesis outflow tract morphogenesis RNA binding phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm DNA repair double-strand break repair chromatin organization protein dephosphorylation cellular response to DNA damage stimulus multicellular organism development pattern specification process pattern specification process mesodermal cell fate specification animal organ morphogenesis response to ionizing radiation striated muscle tissue development histone dephosphorylation histone dephosphorylation nuclear body hydrolase activity protein sumoylation cell differentiation protein-containing complex protein-DNA complex cellular protein localization establishment or maintenance of apical/basal cell polarity peptidyl-tyrosine dephosphorylation aorta morphogenesis ear morphogenesis inner ear morphogenesis inner ear morphogenesis outer ear morphogenesis middle ear morphogenesis cell fate commitment regulation of neuron differentiation regulation of neuron differentiation positive regulation of DNA repair positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding neuron fate specification embryonic skeletal system morphogenesis semicircular canal morphogenesis anatomical structure development anatomical structure development positive regulation of epithelial cell proliferation pharyngeal system development lung epithelial cell differentiation otic vesicle development otic vesicle morphogenesis positive regulation of secondary heart field cardioblast proliferation cochlea morphogenesis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
|
| TC0X00003241.mm.2 |
Ptchd1 |
patched domain containing 1 |
X |
-155569735 |
NM_001093750, BC116312, BC116313 NM_001093750, BC116312, BC116313 NM_001093750, BC116312, BC116313 |
211612 |
18 |
protein binding plasma membrane plasma membrane smoothened signaling pathway chemical synaptic transmission short-term memory long-term memory membrane integral component of membrane thalamus development social behavior synapse synapse cognition cognition cognition excitatory chemical synaptic transmission inhibitory chemical synaptic transmission |
|
| TC0100001550.mm.2 |
Aldh9a1 |
aldehyde dehydrogenase 9, subfamily A1 |
1 |
167349990 |
NM_019993, BC003297 NM_019993, BC003297 |
56752 |
27 |
aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase (NAD+) activity cytoplasm mitochondrion cytosol cytosol cellular aldehyde metabolic process carnitine metabolic process oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor aminobutyraldehyde dehydrogenase activity aminobutyraldehyde dehydrogenase activity neurotransmitter biosynthetic process identical protein binding amine binding 4-trimethylammoniobutyraldehyde dehydrogenase activity 4-trimethylammoniobutyraldehyde dehydrogenase activity NAD binding protein homotetramerization |
00010 00053 00071 00280 00310 00330 00340 00380 00410 00561 00620 00640 01100 |
| TC0900000046.mm.2 |
Mmp12 |
matrix metallopeptidase 12 |
9 |
7347373, 7344396 |
NM_008605, BC019135 NM_008605, BC019135 |
17381 |
159 |
negative regulation of transcription by RNA polymerase II core promoter sequence-specific DNA binding metalloendopeptidase activity metalloendopeptidase activity calcium ion binding collagen binding extracellular region extracellular region extracellular space extracellular space extracellular space nucleus nucleus cytoplasm proteolysis protein import into nucleus protein import into nucleus peptidase activity metallopeptidase activity zinc ion binding positive regulation of gene expression hydrolase activity extracellular matrix organization collagen catabolic process extracellular matrix positive regulation of interferon-alpha production wound healing, spreading of epidermal cells wound healing sequence-specific DNA binding positive regulation of transcription by RNA polymerase II metal ion binding lung alveolus development regulation of defense response to virus by host positive regulation of epithelial cell proliferation involved in wound healing elastin catabolic process negative regulation of type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway bronchiole development bronchiole development cellular response to virus regulation of trophoblast cell migration negative regulation of endothelial cell-matrix adhesion via fibronectin |
|
| TC0300001137.mm.2 |
Sort1 |
sortilin 1 |
3 |
108284063 |
NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343 |
20661 |
120 |
ossification protein binding nucleus lysosome endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein targeting to lysosome post-Golgi vesicle-mediated transport Golgi to endosome transport Golgi to endosome transport endocytosis endocytosis endocytosis G protein-coupled receptor signaling pathway neuropeptide signaling pathway multicellular organism development endosome to lysosome transport extrinsic apoptotic signaling pathway via death domain receptors cell surface endosome membrane nerve growth factor receptor activity regulation of gene expression myotube differentiation myotube differentiation membrane integral component of membrane integral component of membrane vesicle organization vesicle organization vesicle organization enzyme binding clathrin-coated vesicle trans-Golgi network transport vesicle cell differentiation neurotensin receptor activity, non-G protein-coupled dendrite cytoplasmic vesicle membrane cytoplasmic vesicle endosome transport via multivesicular body sorting pathway response to insulin response to insulin neuronal cell body intracellular membrane-bounded organelle negative regulation of fat cell differentiation glucose import glucose import neurotrophin TRK receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity Golgi to lysosome transport positive regulation of epithelial cell apoptotic process retromer complex binding |
04142 04722 |
| TC0100003069.mm.2 |
Cdk18 |
cyclin-dependent kinase 18 |
1 |
-132113546 |
NM_008795, BC119617 NM_008795, BC119617 |
18557 |
20 |
regulation of transcription involved in G1/S transition of mitotic cell cycle nucleotide binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein phosphorylation kinase activity phosphorylation transferase activity |
|
| TC1100004058.mm.2 |
|
|
|
|
NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 NM_199201, BC120623, NM_001101656, NM_001101657, CD300(Cd300lh),, BC119352, CD300 |
|
|
immune system process molecular_function transmembrane signaling receptor activity protein binding cellular_component lysosome endosome plasma membrane biological_process membrane integral component of membrane positive regulation of protein ubiquitination positive regulation of toll-like receptor 9 signaling pathway positive regulation of toll-like receptor 9 signaling pathway |
|
| TC0300001856.mm.2 |
Ccna2 |
cyclin A2 |
3 |
-36564864 |
NM_009828, BC052730 NM_009828, BC052730 |
12428 |
199 |
regulation of cyclin-dependent protein serine/threonine kinase activity G2/M transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex female pronucleus male pronucleus protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm cytosol regulation of DNA replication cell cycle cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity histone phosphorylation protein kinase binding protein kinase binding protein domain specific binding mitotic cell cycle phase transition cell cycle G1/S phase transition positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fibroblast proliferation cell division cyclin A2-CDK2 complex cyclin A2-CDK2 complex cyclin A2-CDK2 complex |
04110 04914 |
| TC1300001837.mm.2 |
Eef1e1 |
eukaryotic translation elongation factor 1 epsilon 1 |
13 |
-38645690 |
NM_025380, BC048466 NM_025380, BC048466 |
66143 |
27 |
protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol translation negative regulation of cell population proliferation aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex positive regulation of apoptotic process positive regulation of DNA damage response, signal transduction by p53 class mediator cellular response to leukemia inhibitory factor positive regulation of cellular senescence positive regulation of apoptotic signaling pathway |
|
| TC0300002313.mm.2 |
Lmna |
lamin A |
3 |
-88481147, -88483204, -88483204 |
NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 |
16905 |
327 |
protein binding nucleus nucleus nuclear envelope nuclear envelope nuclear envelope lamin filament nucleoplasm nucleoplasm cytosol intermediate filament protein import into nucleus nucleus organization nucleus organization nuclear envelope organization nuclear envelope organization muscle organ development protein phosphatase 1 binding negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix nuclear body nuclear speck establishment of cell polarity regulation of cell migration establishment or maintenance of microtubule cytoskeleton polarity regulation of protein stability nuclear membrane regulation of telomere maintenance protein localization to nucleus cellular protein localization site of double-strand break identical protein binding positive regulation of osteoblast differentiation perinuclear region of cytoplasm ventricular cardiac muscle cell development negative regulation of mesenchymal cell proliferation negative regulation of release of cytochrome c from mitochondria positive regulation of cell aging positive regulation of histone H3-K9 trimethylation negative regulation of cardiac muscle hypertrophy in response to stress negative regulation of adipose tissue development DNA double-strand break attachment to nuclear envelope negative regulation of extrinsic apoptotic signaling pathway |
05410 05412 05414 |
| TC1200000664.mm.2 |
Rhoj |
ras homolog family member J |
12 |
75308312 |
NM_023275, BC043719 NM_023275, BC043719 |
80837 |
34 |
nucleotide binding angiogenesis GTPase activity GTPase activity GTPase activity protein binding GTP binding GTP binding intracellular anatomical structure plasma membrane endocytosis small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape regulation of endothelial cell migration membrane cell migration cell projection assembly actin cytoskeleton organization actin cytoskeleton organization Cdc42 protein signal transduction retina vasculature morphogenesis in camera-type eye positive regulation of cell migration involved in sprouting angiogenesis regulation of sprouting angiogenesis |
|
| TC1100001592.mm.2 |
Igfbp4 |
insulin-like growth factor binding protein 4 |
11 |
99041243 |
NM_010517, BC019836 NM_010517, BC019836 |
16010 |
101 |
regulation of cell growth protein binding insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space regulation of glucose metabolic process growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding regulation of growth positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation |
|
| TC0300000656.mm.2 |
Tmem154 |
transmembrane protein 154 |
3 |
84666191 |
NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 |
320782 |
11 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC1900001498.mm.2 |
Blnk |
B cell linker |
19 |
-40928926 |
NM_008528, BC059785 NM_008528, BC059785 |
17060 |
107 |
protein binding cytoplasm cytoplasm cytosol plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of gene expression membrane enzyme binding intracellular signal transduction intracellular signal transduction signaling adaptor activity cytoplasmic ribonucleoprotein granule B cell activation SH2 domain binding B cell receptor signaling pathway protein tyrosine kinase binding |
04380 04662 05340 |
| TC1300001633.mm.2 |
H3c6 |
H3 clustered histone 6 |
13 |
-23561474 |
NM_178205, BC156786 NM_178205, BC156786 |
319151 |
11 |
nuclear chromosome chromatin nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1300001561.mm.2 |
H3c11 |
H3 clustered histone 11 |
13 |
-21782914 |
NM_178207, BC116383 NM_178207, BC116383 |
319153 |
10 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1000002453.mm.2 |
Pdxk |
pyridoxal (pyridoxine, vitamin B6) kinase |
10 |
-78436746 |
NM_172134, BC027745 NM_172134, BC027745 |
216134 |
31 |
nucleotide binding magnesium ion binding ATP binding nucleoplasm cytoplasm cytosol zinc ion binding pyridoxal kinase activity pyridoxal kinase activity pyridoxal 5'-phosphate salvage pyridoxal 5'-phosphate salvage kinase activity phosphorylation transferase activity pyridoxal phosphate binding potassium ion binding sodium ion binding lithium ion binding small molecule binding protein homodimerization activity pyridoxal phosphate biosynthetic process negative regulation of apoptotic process metal ion binding pyridoxal binding |
00750 01100 |
| TC1200001324.mm.2 |
Cdca7l |
cell division cycle associated 7 like |
12 |
117843860 |
NM_146040, BC006933 NM_146040, BC006933 |
217946 |
19 |
fibrillar center nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol regulation of transcription, DNA-templated positive regulation of cell population proliferation |
|
| TC0800000955.mm.2 |
Cacna1a |
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
8 |
84415363 |
NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578 NM_001252059, NM_001252060, NM_001252061, NM_007578 |
12286 |
343 |
regulation of neurotransmitter levels ion channel activity voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity calcium channel activity protein binding calmodulin binding nucleus cytoplasm plasma membrane voltage-gated calcium channel complex voltage-gated calcium channel complex ion transport calcium ion transport calcium ion transport calcium ion transport positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration gamma-aminobutyric acid signaling pathway chemical synaptic transmission chemical synaptic transmission chemical synaptic transmission neuron-neuron synaptic transmission neuromuscular synaptic transmission synapse assembly adult walking behavior adult walking behavior cell death high voltage-gated calcium channel activity high voltage-gated calcium channel activity high voltage-gated calcium channel activity regulation of hormone levels gamma-aminobutyric acid secretion regulation of acetylcholine secretion, neurotransmission membrane integral component of membrane calcium-ion regulated exocytosis regulation of calcium ion-dependent exocytosis transmission of nerve impulse sensory perception of pain syntaxin binding spinal cord motor neuron differentiation cerebellum maturation cerebellar molecular layer development cerebellar Purkinje cell layer development cerebellar Purkinje cell differentiation vestibular nucleus development central nervous system neuron differentiation dendrite cellular chloride ion homeostasis regulation of sulfur amino acid metabolic process negative regulation of hormone biosynthetic process protein-containing complex regulation of ion transmembrane transport synaptic transmission, glutamatergic regulation of membrane potential glucose homeostasis cell projection neuronal cell body neuronal cell body receptor clustering perikaryon negative regulation of neuron apoptotic process metal ion binding response to pain behavioral response to pain calcium ion-regulated exocytosis of neurotransmitter dendrite morphogenesis regulation of axonogenesis modulation of chemical synaptic transmission nervous system process musculoskeletal movement, spinal reflex action neuromuscular process controlling balance neuromuscular process neuromuscular process membrane depolarization transmembrane transport rhythmic synaptic transmission calcium ion import calcium ion import calcium ion transmembrane transport glutamatergic synapse glutamatergic synapse integral component of presynaptic active zone membrane voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels regulation of voltage-gated calcium channel activity response to amyloid-beta cellular response to amyloid-beta |
04010 04020 04730 04742 04930 |
| TC1900000152.mm.2 |
Wdr74 |
WD repeat domain 74 |
19 |
8735838 |
NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478 |
107071 |
21 |
nuclear exosome (RNase complex) blastocyst formation molecular_function nucleus nucleus nucleoplasm nucleolus nucleolus rRNA processing RNA metabolic process preribosome, large subunit precursor ribosomal large subunit biogenesis ribosomal large subunit biogenesis |
|
| TC1000002650.mm.2 |
Utp20 |
UTP20 small subunit processome component |
10 |
-88746606 |
NM_175158 |
70683 |
20 |
nucleus nucleolus nucleolus plasma membrane rRNA processing 90S preribosome small-subunit processome |
|
| TC1200001990.mm.2 |
Actn1 |
actinin, alpha 1 |
12 |
-80167541 |
NM_134156, BC054830 NM_134156, BC054830 |
109711 |
100 |
stress fiber stress fiber stress fiber ruffle ruffle double-stranded RNA binding actin binding integrin binding integrin binding calcium ion binding protein binding cytoskeletal regulatory protein binding nucleus cytoplasm cytoskeleton actin filament plasma membrane brush border cell-cell junction fascia adherens focal adhesion focal adhesion actin filament organization membrane vinculin binding vinculin binding protein domain specific binding sarcomere Z disc Z disc cell junction secretory granule platelet formation nuclear receptor coactivator activity cortical cytoskeleton cortical actin cytoskeleton cortical cytoskeleton organization dense core granule membrane platelet morphogenesis protein homodimerization activity protein homodimerization activity cell projection dendritic spine ion channel binding metal ion binding focal adhesion assembly synapse organization actin filament binding actin filament binding actin filament bundle assembly negative regulation of cellular component movement actin filament network formation actin crosslink formation glutamatergic synapse postsynapse organization structural constituent of postsynapse |
04510 04520 04530 04670 04810 05146 05322 05412 |
| TC1900001266.mm.2 |
Mamdc2 |
MAM domain containing 2 |
19 |
-23302608 |
NM_174857, BC042773 NM_174857, BC042773 |
71738 |
14 |
glycosaminoglycan binding extracellular region interstitial matrix endoplasmic reticulum membrane peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix |
|
| TC1900000491.mm.2 |
Lipn |
lipase, family member N |
19 |
34067357 |
NM_027340 |
70166 |
12 |
extracellular region lipid metabolic process lipid catabolic process hydrolase activity hydrolase activity, acting on ester bonds intracellular membrane-bounded organelle |
|
| TC0600000324.mm.2 |
Akr1b8 |
aldo-keto reductase family 1, member B8 |
6 |
34354145 |
NM_008012, BC005789 NM_008012, BC005789 |
14187 |
23 |
retinoid metabolic process retinal dehydrogenase activity alditol:NADP+ 1-oxidoreductase activity cytoplasm mitochondrion cytosol alcohol dehydrogenase (NADP+) activity farnesol catabolic process oxidoreductase activity daunorubicin metabolic process doxorubicin metabolic process geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity cellular detoxification of aldehyde |
00040 00051 00052 00561 00620 01100 |
| TC0100003522.mm.2 |
Fcgr2b |
Fc receptor, IgG, low affinity IIb |
1 |
-170960558 |
NM_001077189, NM_010187, BC038070 NM_001077189, NM_010187, BC038070 NM_001077189, NM_010187, BC038070 |
14130 |
472 |
amyloid-beta binding negative regulation of type I hypersensitivity immune complex clearance negative regulation of immunoglobulin production negative regulation of inflammatory response to antigenic stimulus negative regulation of acute inflammatory response to antigenic stimulus negative regulation of humoral immune response mediated by circulating immunoglobulin transmembrane signaling receptor activity protein binding extracellular region cytoplasm cytoskeleton plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane integral component of plasma membrane receptor-mediated endocytosis phagocytosis, engulfment defense response cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane cell surface membrane integral component of membrane immunoglobulin mediated immune response dendrite development low-affinity IgG receptor activity IgG binding IgG binding immunoglobulin binding antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation endocytic recycling negative regulation of interleukin-10 production negative regulation of neutrophil apoptotic process Fc-gamma receptor signaling pathway involved in phagocytosis dendritic spine cell body protein-containing complex binding membrane raft positive regulation of JNK cascade regulation of long-term neuronal synaptic plasticity negative regulation of phagocytosis positive regulation of phagocytosis regulation of immune response negative regulation of immune response negative regulation of B cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity recycling endosome cellular response to molecule of bacterial origin positive regulation of neuron death positive regulation of neuron death regulation of dendritic spine maintenance regulation of dendritic spine maintenance cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of response to endoplasmic reticulum stress positive regulation of response to endoplasmic reticulum stress |
04145 04380 04662 04666 05150 05322 |
| TC1000003117.mm.2 |
Shmt2 |
serine hydroxymethyltransferase 2 (mitochondrial) |
10 |
-127517122 |
NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 |
108037 |
33 |
translation repressor activity, mRNA regulatory element binding regulation of oxidative phosphorylation regulation of oxidative phosphorylation regulation of oxidative phosphorylation chromatin binding catalytic activity glycine hydroxymethyltransferase activity glycine hydroxymethyltransferase activity nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial intermembrane space mitochondrial matrix mitochondrial matrix cytosol glycine metabolic process glycine biosynthetic process L-serine metabolic process L-serine biosynthetic process L-serine catabolic process one-carbon metabolic process one-carbon metabolic process zinc ion binding positive regulation of cell population proliferation L-allo-threonine aldolase activity purine nucleobase biosynthetic process microtubule cytoskeleton membrane amino acid binding transferase activity glycine biosynthetic process from serine glycine biosynthetic process from serine pyridoxal phosphate binding pyridoxal phosphate binding response to type I interferon response to type I interferon tetrahydrofolate interconversion mitochondrial nucleoid identical protein binding protein homodimerization activity tetrahydrofolate metabolic process tetrahydrofolate metabolic process folic acid metabolic process mRNA 5'-UTR binding cobalt ion binding protein tetramerization protein homotetramerization protein homotetramerization regulation of mitochondrial translation regulation of mitochondrial translation protein K63-linked deubiquitination BRISC complex BRISC complex serine binding regulation of aerobic respiration regulation of aerobic respiration |
00260 00460 00670 01100 |
| TC1400000940.mm.2 |
Pbk |
PDZ binding kinase |
14 |
65805910 |
NM_023209, BC020099 NM_023209, BC020099 |
52033 |
33 |
nucleotide binding mitotic cell cycle negative regulation of protein phosphorylation protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of stress-activated MAPK cascade cellular response to UV negative regulation of inflammatory response |
|
| TC0100002033.mm.2 |
Mcm3 |
minichromosome maintenance complex component 3 |
1 |
-20802967 |
NM_008563, BC031700 NM_008563, BC031700 |
17215 |
65 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytoplasm centrosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex perinuclear region of cytoplasm mitotic DNA replication initiation |
03030 04110 |
| TC0300002284.mm.2 |
Fcrls |
Fc receptor-like S, scavenger receptor |
3 |
-87250964 |
NM_030707, BC016551 NM_030707, BC016551 |
80891 |
22 |
transmembrane signaling receptor activity integral component of plasma membrane cell surface receptor signaling pathway |
|
| TC1700001622.mm.2 |
|
|
|
|
NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662 |
|
|
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex re-entry into mitotic cell cycle placenta development nucleus nucleus cytoplasm centrosome centrosome centriole cytoskeleton cell cycle negative regulation of centrosome duplication negative regulation of centrosome duplication cyclin-dependent protein serine/threonine kinase regulator activity protein ubiquitination SCF ubiquitin ligase complex cell junction SCF-dependent proteasomal ubiquitin-dependent protein catabolic process mitotic cell cycle phase transition cell division regulation of cell cycle |
|
| TC1300000181.mm.2 |
|
|
|
|
NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 |
|
|
nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity |
|
| TC1300001565.mm.2 |
|
|
|
|
NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 |
|
|
nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity |
|
| TC0800000564.mm.2 |
Dctd |
dCMP deaminase |
8 |
48109957, 48110012, 48099091 |
NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 |
320685 |
16 |
catalytic activity dCMP deaminase activity pyrimidine nucleotide metabolic process dUMP biosynthetic process dTMP biosynthetic process metabolic process zinc ion binding nucleotide biosynthetic process hydrolase activity identical protein binding metal ion binding |
00240 01100 |
| TC0100002576.mm.2 |
Tns1 |
tensin 1 |
1 |
-73910231 |
NM_001289895, NM_027884 NM_001289895, NM_027884 |
21961 |
27 |
actin binding focal adhesion focal adhesion cell-substrate junction assembly fibroblast migration cell-substrate junction |
|
| TC0100001387.mm.2 |
|
|
|
|
NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086 |
|
|
nucleotide binding magnesium ion binding angiogenesis catalytic activity glutamate-ammonia ligase activity glutamate-ammonia ligase activity protein binding ATP binding cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion endoplasmic reticulum rough endoplasmic reticulum cytosol plasma membrane glutamate metabolic process glutamine biosynthetic process glutamine biosynthetic process nitrogen compound metabolic process cell population proliferation cellular response to starvation response to glucose regulation of endothelial cell migration regulation of endothelial cell migration membrane glutamate binding transferase activity ligase activity protein palmitoylation ammonia assimilation cycle protein-cysteine S-palmitoyltransferase activity manganese ion binding positive regulation of insulin secretion protein-containing complex ribosome biogenesis identical protein binding cell projection neuron projection perikaryon myelin sheath myelin sheath intracellular membrane-bounded organelle axon terminus cell body dynein light chain binding metal ion binding positive regulation of epithelial cell proliferation positive regulation of synaptic transmission, glutamatergic glial cell projection regulation of sprouting angiogenesis regulation of sprouting angiogenesis regulation of protein localization to nucleolus |
|
| TC0100003697.mm.2 |
Lbr |
lamin B receptor |
1 |
-181815314 |
NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522 |
98386 |
67 |
DNA binding protein binding nucleus nuclear envelope nuclear envelope nuclear inner membrane nuclear inner membrane nuclear pore nuclear lamina cytoplasm endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process nuclear localization sequence binding steroid metabolic process cholesterol metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor neutrophil differentiation nuclear membrane nuclear membrane delta14-sterol reductase activity delta14-sterol reductase activity chaperone binding chromo shadow domain binding NADPH binding |
|
| TC0500003632.mm.2 |
Slc46a3 |
solute carrier family 46, member 3 |
5 |
-147875897 |
NM_027872, BC006902 NM_027872, BC006902 |
71706 |
18 |
membrane integral component of membrane transmembrane transporter activity vacuolar transmembrane transport transmembrane transport integral component of lysosomal membrane |
|
| TC1700000937.mm.2 |
Trem2 |
triggering receptor expressed on myeloid cells 2 |
17 |
48346400 |
NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 NM_001272078, NM_031254, BC032959, BC033485, BC052784 |
83433 |
169 |
lipopolysaccharide binding amyloid-beta binding microglial cell activation microglial cell activation positive regulation of protein phosphorylation microglial cell activation involved in immune response positive regulation of antigen processing and presentation of peptide antigen via MHC class II response to ischemia transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding phospholipid binding extracellular region plasma membrane plasma membrane plasma membrane integral component of plasma membrane phagocytosis, engulfment phagocytosis, engulfment high-density lipoprotein particle binding lipid binding regulation of gene expression regulation of gene expression negative regulation of autophagy negative regulation of autophagy positive regulation of gene expression positive regulation of mitochondrion organization membrane integral component of membrane low-density lipoprotein particle binding osteoclast differentiation intrinsic component of plasma membrane lipopolysaccharide-mediated signaling pathway regulation of TOR signaling positive regulation of TOR signaling detection of lipopolysaccharide detection of peptidoglycan regulation of interleukin-6 production negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production positive regulation of interleukin-10 production apolipoprotein binding apolipoprotein A-I binding very-low-density lipoprotein particle binding positive regulation of macrophage fusion signaling receptor activity defense response to bacterium peptidoglycan binding negative regulation of apoptotic process apoptotic cell clearance plasma membrane raft protein-containing complex binding innate immune response regulation of innate immune response positive regulation of osteoclast differentiation astrocyte activation positive regulation of protein secretion regulation of peptidyl-tyrosine phosphorylation regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of calcium-mediated signaling positive regulation of chemotaxis regulation of resting membrane potential positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment microglial cell proliferation positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid lipoteichoic acid binding cellular response to lipoteichoic acid cellular response to peptidoglycan regulation of macrophage inflammatory protein 1 alpha production lipoprotein particle binding dendritic cell differentiation scaffold protein binding amyloid-beta clearance import into cell regulation of plasma membrane bounded cell projection organization regulation of plasma membrane bounded cell projection organization regulation of plasma membrane bounded cell projection organization complement-mediated synapse pruning neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of amyloid-beta clearance positive regulation of engulfment of apoptotic cell positive regulation of NIK/NF-kappaB signaling positive regulation of proteasomal protein catabolic process positive regulation of inward rectifier potassium channel activity regulation of intracellular signal transduction positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of microglial cell activation positive regulation of microglial cell activation positive regulation of microglial cell activation negative regulation of autophagic cell death positive regulation of microglial cell migration positive regulation of microglial cell migration cellular response to amyloid-beta positive regulation of CAMKK-AMPK signaling cascade protein tyrosine kinase binding positive regulation of CD40 signaling pathway positive regulation of ATP biosynthetic process |
04380 |
| TC1000001894.mm.2 |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
10 |
-24637913 |
NM_008813, BC160371 NM_008813, BC160371 |
18605 |
131 |
nucleic acid binding catalytic activity exonuclease activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity nucleotide diphosphatase activity nucleotide diphosphatase activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding extracellular region extracellular space extracellular space plasma membrane integral component of plasma membrane generation of precursor metabolites and energy phosphate-containing compound metabolic process immune response zinc ion binding nucleoside triphosphate catabolic process nucleoside triphosphate catabolic process cell surface cell surface cell surface membrane integral component of membrane hydrolase activity polysaccharide binding negative regulation of ossification negative regulation of cell growth melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport inorganic diphosphate transport cellular phosphate ion homeostasis sequestering of triglyceride biomineral tissue development negative regulation of protein autophosphorylation cellular response to insulin stimulus NADH pyrophosphatase activity identical protein binding protein homodimerization activity cell projection neuron projection neuronal cell body cell body synapse negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process ATP metabolic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway bone remodeling metal ion binding nucleoside-triphosphate diphosphatase activity nucleoside-triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process nucleic acid phosphodiester bond hydrolysis apical dendrite basal dendrite cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity negative regulation of hh target transcription factor activity |
00230 00500 00740 00760 00770 01100 |
| TC1900000508.mm.2 |
Kif20b |
kinesin family member 20B |
19 |
34922357 |
NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148 |
240641 |
35 |
nucleotide binding neural tube closure microtubule motor activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytosol cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle regulation of mitotic nuclear division microtubule binding microtubule binding positive regulation of cell population proliferation positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed microtubule cytoskeleton ATPase activity ATPase activity midbody midbody positive regulation of cytokinesis protein localization to microtubule protein homodimerization activity cell projection intercellular bridge perinuclear region of cytoplasm neuron projection morphogenesis WW domain binding spindle midzone cell division regulation of establishment of protein localization contractile ring positive regulation of intracellular protein transport mitotic spindle pole positive regulation of mitotic cytokinetic process mitotic spindle midzone regulation of establishment of cell polarity regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration |
|
| TC1700001173.mm.2 |
Rasgrp3 |
RAS, guanyl releasing protein 3 |
17 |
75435904, 75465537 |
NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 |
240168 |
21 |
guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm Ras protein signal transduction kinase binding small GTPase binding small GTPase binding guanyl-nucleotide exchange factor complex regulation of GTPase activity perinuclear region of cytoplasm |
04010 04662 |
| TC1100002001.mm.2 |
Slc26a11 |
solute carrier family 26, member 11 |
11 |
119355556 |
NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897 |
268512 |
17 |
nucleoplasm lysosome lysosomal membrane endoplasmic reticulum Golgi apparatus plasma membrane integral component of plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity sulfate transmembrane transporter activity anion:anion antiporter activity membrane integral component of membrane intracellular membrane-bounded organelle transmembrane transport |
|
| TC0400002010.mm.2 |
Nol9 |
nucleolar protein 9 |
4 |
152039320, 152039320, 152039337 |
NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 |
74035 |
19 |
nucleotide binding cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA RNA binding ATP binding nucleus nucleolus rRNA processing RNA processing kinase activity transferase activity intermediate filament cytoskeleton polynucleotide 5'-hydroxyl-kinase activity polynucleotide 5'-hydroxyl-kinase activity |
|
| TC0100002965.mm.2 |
Steap3 |
STEAP family member 3 |
1 |
-120226413, -120226413, -120226413, -120226413 |
NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435 |
68428 |
33 |
ferric-chelate reductase activity ferric-chelate reductase activity protein binding cytoplasm endosome endosome multivesicular body plasma membrane plasma membrane ion transport iron ion transport apoptotic process cell cycle cupric reductase activity cupric reductase activity protein secretion protein secretion copper ion import copper ion import copper ion import membrane integral component of membrane oxidoreductase activity iron import into cell identical protein binding positive regulation of apoptotic process metal ion binding ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity iron ion homeostasis iron ion import across cell outer membrane iron ion import across cell outer membrane positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator exosomal secretion |
04115 |
| TC0300002500.mm.2 |
H3c15 |
H3 clustered histone 15 |
3 |
96246699, -96238478 |
NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 |
97114 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC0300003216.mm.2 |
|
|
|
|
NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 |
|
|
negative regulation of transcription by RNA polymerase II nuclear chromosome nucleosome chromatin binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
|
| TC0200002990.mm.2 |
Hacd1 |
3-hydroxyacyl-CoA dehydratase 1 |
2 |
-14026830 |
NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 |
30963 |
14 |
endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development regulation of G2/M transition of mitotic cell cycle positive regulation of cell-substrate adhesion myotube differentiation membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation cellular protein-containing complex assembly very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process hydroxyapatite binding cementum mineralization 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity regulation of G1/S transition of mitotic cell cycle |
|
| TC0700000236.mm.2 |
Slc1a5 |
solute carrier family 1 (neutral amino acid transporter), member 5 |
7 |
16781345 |
NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462 |
20514 |
33 |
plasma membrane plasma membrane amino acid transport glutamine transport basal plasma membrane glutamine secretion neutral amino acid transmembrane transporter activity L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity symporter activity L-serine transport membrane integral component of membrane metal ion binding protein homotrimerization L-aspartate import across plasma membrane L-aspartate import across plasma membrane transport across blood-brain barrier L-glutamine import across plasma membrane |
04974 |
| TC1300000972.mm.2 |
Mef2c |
myocyte enhancer factor 2C |
13 |
83504033, 83573606, 83524742, 83523655 |
NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 |
17260 |
401 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade MAPK cascade transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development osteoblast differentiation osteoblast differentiation neuron migration B cell homeostasis heart looping endochondral ossification endochondral ossification blood vessel remodeling chondrocyte differentiation germinal center formation regulation of germinal center formation primary heart field specification secondary heart field specification outflow tract morphogenesis sinoatrial valve morphogenesis cardiac ventricle formation cardiac ventricle formation DNA binding DNA binding minor groove of adenine-thymine-rich DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II apoptotic process humoral immune response multicellular organism development nervous system development heart development heart development skeletal muscle tissue development muscle cell fate determination learning or memory positive regulation of cardiac muscle hypertrophy positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of alkaline phosphatase activity neural crest cell differentiation cardiac muscle hypertrophy in response to stress nuclear speck sarcomere cell differentiation neuron differentiation platelet formation monocyte differentiation negative regulation of ossification melanocyte differentiation positive regulation of bone mineralization positive regulation of B cell proliferation protein-containing complex activating transcription factor binding cellular response to drug skeletal muscle cell differentiation skeletal muscle cell differentiation cellular response to trichostatin A B cell proliferation histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding cell fate commitment regulation of megakaryocyte differentiation positive regulation of myoblast differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion protein heterodimerization activity protein dimerization activity regulation of synaptic plasticity positive regulation of skeletal muscle tissue development neuron development cell morphogenesis involved in neuron differentiation embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis negative regulation of epithelial cell proliferation B cell receptor signaling pathway smooth muscle cell differentiation regulation of synapse assembly regulation of synaptic transmission, glutamatergic cardiac muscle cell differentiation cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation roof of mouth development regulation of synaptic activity positive regulation of cardiac muscle cell proliferation excitatory postsynaptic potential transdifferentiation regulation of sarcomere organization cartilage morphogenesis regulation of dendritic spine development renal tubule morphogenesis cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to growth factor stimulus cellular response to parathyroid hormone stimulus cellular response to fluid shear stress cellular response to transforming growth factor beta stimulus HMG box domain binding positive regulation of cell proliferation in bone marrow glomerulus morphogenesis nephron tubule epithelial cell differentiation negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular endothelial cell proliferation sequence-specific double-stranded DNA binding positive regulation of macrophage apoptotic process regulation of NMDA receptor activity regulation of AMPA receptor activity positive regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell differentiation positive regulation of behavioral fear response epithelial cell proliferation involved in renal tubule morphogenesis positive regulation of skeletal muscle cell differentiation |
04010 |
| TC1100003470.mm.2 |
Prr11 |
proline rich 11 |
11 |
-87089155 |
NM_175563, BC023918 NM_175563, BC023918 |
270906 |
14 |
molecular_function nucleus nucleus cytoplasm cytoplasm cell cycle arrest regulation of cell cycle |
|
| TC0200002474.mm.2 |
Srsf6 |
serine and arginine-rich splicing factor 6 |
2 |
162931507 |
NM_026499, BC012039 NM_026499, BC012039 |
67996 |
30 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus mRNA splice site selection mRNA splice site selection mRNA processing RNA splicing negative regulation of gene expression regulation of keratinocyte proliferation nuclear speck nuclear speck pre-mRNA binding negative regulation of keratinocyte differentiation negative regulation of mRNA splicing, via spliceosome positive regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of cell death regulation of wound healing negative regulation of type B pancreatic cell apoptotic process |
03040 |
| TC0400003390.mm.2 |
Cdc20 |
cell division cycle 20 |
4 |
-118432900 |
NM_023223, BC003215 NM_023223, BC003215 |
107995 |
81 |
mitotic metaphase protein binding nucleoplasm anaphase-promoting complex anaphase-promoting complex cytoplasm centrosome cytosol cytoskeleton cell cycle mitotic sister chromatid cohesion nervous system development protein C-terminus binding positive regulation of cell population proliferation anaphase-promoting complex binding enzyme binding cell differentiation anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of synaptic plasticity protein-containing complex regulation of meiotic nuclear division histone deacetylase binding perinuclear region of cytoplasm regulation of dendrite development cell division positive regulation of synapse maturation mitotic spindle assembly ubiquitin-protein transferase activator activity positive regulation of ubiquitin protein ligase activity positive regulation of anaphase-promoting complex-dependent catabolic process ubiquitin ligase activator activity |
04110 04114 04120 |
| TC1300000174.mm.2 |
H3c10 |
H3 clustered histone 10 |
13 |
21717627 |
NM_178206 |
319152 |
3 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC0600001279.mm.2 |
Pparg |
peroxisome proliferator activated receptor gamma |
6 |
115422065, 115360950, 115362348, 115361143 |
NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798 |
19016 |
1453 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific negative regulation of cytokine production placenta development response to dietary excess diet induced thermogenesis negative regulation of acute inflammatory response DNA binding DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity steroid hormone receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II fatty acid metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response signal transduction protein C-terminus binding transcription factor binding regulation of blood pressure zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation response to light stimulus hormone-mediated signaling pathway regulation of gene expression macrophage derived foam cell differentiation negative regulation of macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of cholesterol storage negative regulation of sequestering of triglyceride long-chain fatty acid transport negative regulation of angiogenesis regulation of lipid metabolic process regulation of lipid metabolic process fatty acid oxidation enzyme binding protein phosphatase binding cell differentiation monocyte differentiation negative regulation of cell growth estrogen receptor binding nuclear receptor coactivator activity negative regulation of BMP signaling pathway epithelial cell differentiation response to food cellular response to insulin stimulus cellular response to insulin stimulus negative regulation of collagen biosynthetic process activating transcription factor binding response to lipid response to lipid peroxisome proliferator activated receptor signaling pathway peroxisome proliferator activated receptor signaling pathway peptide binding glucose homeostasis regulation of circadian rhythm identical protein binding lipoprotein transport positive regulation of apoptotic process intracellular membrane-bounded organelle receptor complex positive regulation of DNA binding negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding protein self-association cell fate commitment cell fate commitment fat cell differentiation fat cell differentiation fat cell differentiation fat cell differentiation regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation negative regulation of osteoblast differentiation negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fatty acid metabolic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fatty acid oxidation metal ion binding retinoid X receptor binding retinoic acid receptor signaling pathway retinoic acid receptor signaling pathway cell maturation perinuclear region of cytoplasm rhythmic process negative regulation of smooth muscle cell proliferation positive regulation of oligodendrocyte differentiation arachidonic acid binding DNA binding domain binding LBD domain binding WW domain binding negative regulation of inflammatory response white fat cell differentiation white fat cell differentiation brown fat cell differentiation positive regulation of DNA-binding transcription factor activity alpha-actinin binding negative regulation of telomerase activity positive regulation of phagocytosis, engulfment negative regulation of interferon-gamma-mediated signaling pathway negative regulation of gene silencing by miRNA E-box binding cellular response to lithium ion cellular response to low-density lipoprotein particle stimulus cellular response to organic cyclic compound negative regulation of peptide hormone secretion RNA polymerase II transcription regulator complex negative regulation of neuroinflammatory response negative regulation of cellular response to insulin stimulus positive regulation of pri-miRNA transcription by RNA polymerase II negative regulation of microglial cell activation negative regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular endothelial cell proliferation positive regulation of low-density lipoprotein receptor activity promoter-specific chromatin binding negative regulation of pancreatic stellate cell proliferation negative regulation of signaling receptor activity |
03320 04380 05016 05200 05216 |
| TC0200005164.mm.2 |
Sulf2 |
sulfatase 2 |
2 |
-166073898, -166073898 |
NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 |
72043 |
66 |
kidney development chondrocyte development glomerular filtration catalytic activity arylsulfatase activity calcium ion binding glycosaminoglycan binding extracellular space endoplasmic reticulum endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane sulfur compound metabolic process N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity response to wounding cell surface cell surface positive regulation of vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production esophagus smooth muscle contraction hydrolase activity positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process glomerular basement membrane development glomerular basement membrane development glial cell-derived neurotrophic factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway metal ion binding embryonic skeletal system development cartilage development bone development innervation positive regulation of canonical Wnt signaling pathway liver regeneration regulation of hepatocyte proliferation |
|
| TC1900000184.mm.2 |
Rab3il1 |
RAB3A interacting protein (rabin3)-like 1 |
19 |
10018193, 10001668, 10018193, 10018193, 10018250, 10001724, 10015046, 10018250 |
NM_144538, BC020147 NM_144538, BC020147 |
74760 |
19 |
guanyl-nucleotide exchange factor activity exocytosis protein transport kinase binding identical protein binding Golgi to plasma membrane transport vesicle |
|
| TC1600000447.mm.2 |
Tfrc |
transferrin receptor |
16 |
32608895, 32609121 |
NM_011638, BC054522 NM_011638, BC054522 |
22042 |
174 |
positive regulation of protein phosphorylation double-stranded RNA binding transferrin receptor activity transferrin receptor activity iron ion transmembrane transporter activity protein binding extracellular region extracellular space nucleus cytoplasm mitochondrion endosome endosome early endosome plasma membrane plasma membrane integral component of plasma membrane clathrin-coated pit clathrin-coated pit iron ion transport iron ion transport cellular iron ion homeostasis cellular iron ion homeostasis endocytosis receptor-mediated endocytosis external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface endosome membrane positive regulation of gene expression negative regulation of mitochondrial fusion membrane membrane integral component of membrane basolateral plasma membrane protein kinase binding osteoclast differentiation Hsp70 protein binding positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of protein-containing complex assembly cytoplasmic vesicle receptor internalization cellular response to extracellular stimulus positive regulation of peptidyl-serine phosphorylation transferrin transport intracellular signal transduction cellular response to drug positive regulation of T cell proliferation positive regulation of T cell proliferation identical protein binding protein homodimerization activity negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling intracellular membrane-bounded organelle protein-containing complex binding positive regulation of bone resorption positive regulation of isotype switching perinuclear region of cytoplasm perinuclear region of cytoplasm chaperone binding positive regulation of NF-kappaB transcription factor activity recycling endosome recycling endosome recycling endosome membrane extracellular exosome extracellular exosome cellular response to iron ion positive regulation of protein localization to nucleus HFE-transferrin receptor complex HFE-transferrin receptor complex cellular response to leukemia inhibitory factor |
04144 04145 04640 |
| TC0400001107.mm.2 |
Dhcr24 |
24-dehydrocholesterol reductase |
4 |
106561037 |
NM_053272, BC019797 NM_053272, BC019797 |
74754 |
47 |
delta24(24-1) sterol reductase activity delta24(24-1) sterol reductase activity nucleus cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus cytosol cytoskeleton lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process Ras protein signal transduction protein localization steroid metabolic process steroid metabolic process cholesterol metabolic process negative regulation of cell population proliferation tissue development tissue development membrane membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor enzyme binding male genitalia development plasminogen activation peptide antigen binding amyloid precursor protein catabolic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process skin development delta24-sterol reductase activity flavin adenine dinucleotide binding membrane organization FAD binding |
00100 01100 |
| TC1400000975.mm.2 |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
14 |
69337150, 69555400 |
BC043134, NM_026174 BC043134, NM_026174 |
67464 |
23 |
Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane |
00230 00240 04142 |
| TC0200003195.mm.2 |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) |
2 |
-26593056 |
NM_026212, BC125530, BC137840 NM_026212, BC125530, BC137840 NM_026212, BC125530, BC137840 |
67512 |
31 |
positive regulation of cytokine production 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lipid metabolic process phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process phospholipid biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring acyl groups |
00561 00564 01100 04975 |
| TC1300000543.mm.2 |
Rnf144b |
ring finger protein 144B |
13 |
47194002, 47122719 |
NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007 |
218215 |
20 |
ubiquitin ligase complex protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoplasm mitochondrion ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process apoptotic process membrane integral component of membrane protein ubiquitination transferase activity ubiquitin conjugating enzyme binding mitochondrial membrane mitochondrial membrane positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of apoptotic process metal ion binding ubiquitin protein ligase activity |
|
| TC0300002334.mm.2 |
Fdps |
farnesyl diphosphate synthetase |
3 |
-89093587 |
NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 |
110196 |
37 |
dimethylallyltranstransferase activity geranyltranstransferase activity geranyltranstransferase activity nucleoplasm cytoplasm mitochondrion mitochondrial matrix peroxisome cytosol lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process sterol biosynthetic process transferase activity farnesyl diphosphate biosynthetic process farnesyl diphosphate biosynthetic process positive regulation of cholesterol biosynthetic process metal ion binding positive regulation of cell growth involved in cardiac muscle cell development |
00900 01100 |
| TC0100002866.mm.2 |
Pam |
peptidylglycine alpha-amidating monooxygenase |
1 |
-97821093, -97821093 |
NM_013626, BC166013 NM_013626, BC166013 |
18484 |
51 |
peptide amidation long-chain fatty acid metabolic process catalytic activity monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding calcium ion binding extracellular region extracellular space trans-Golgi network cytosol plasma membrane integral component of plasma membrane regulation of transcription by RNA polymerase II peptide metabolic process peptide metabolic process metabolic process zinc ion binding response to pH toxin metabolic process cell surface response to zinc ion membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen lyase activity protein amidation protein metabolic process protein kinase binding secretory granule secretory granule membrane cytoplasmic vesicle L-ascorbic acid binding regulation of actin cytoskeleton organization response to drug identical protein binding neuron projection neuronal cell body perikaryon metal ion binding perinuclear region of cytoplasm regulation of protein secretion fatty acid primary amide biosynthetic process |
|
| TC1500001656.mm.2 |
Sla |
src-like adaptor |
15 |
-66780818 |
NM_001029841, NM_009192, BC032922 NM_001029841, NM_009192, BC032922 NM_001029841, NM_009192, BC032922 |
20491 |
49 |
protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding cytoplasm endosome focal adhesion transmembrane receptor protein tyrosine kinase signaling pathway regulation of signal transduction cell differentiation extrinsic component of cytoplasmic side of plasma membrane dendritic spine innate immune response |
|
| TC0900002369.mm.2 |
Scamp5 |
secretory carrier membrane protein 5 |
9 |
-57441326 |
NM_020270, BC018613 NM_020270, BC018613 |
56807 |
22 |
Golgi membrane positive regulation of cytokine production endosome Golgi apparatus plasma membrane exocytosis synaptic vesicle synaptic vesicle protein transport membrane integral component of membrane cell junction integral component of synaptic vesicle membrane cytoplasmic vesicle trans-Golgi network membrane trans-Golgi network membrane response to endoplasmic reticulum stress protein-containing complex binding synapse negative regulation of endocytosis positive regulation of calcium ion-dependent exocytosis recycling endosome membrane recycling endosome membrane regulation of synaptic vesicle endocytosis |
|
| TC0200004811.mm.2 |
Cd93 |
CD93 antigen |
2 |
-148436650 |
NM_010740, BC156937, CD93 NM_010740, BC156937, CD93 NM_010740, BC156937, CD93 |
17064 |
42 |
complement component C1q complex binding calcium ion binding plasma membrane plasma membrane cell adhesion cell surface membrane integral component of membrane carbohydrate binding cytoplasmic vesicle cell-cell adhesion cell-cell adhesion |
|
| TC1300001576.mm.2 |
|
|
|
|
NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373 |
|
|
DNA binding nucleus chromatin silencing negative regulation of cell population proliferation |
|
| TC1800000528.mm.2 |
Sncaip |
synuclein, alpha interacting protein (synphilin) |
18 |
52768092, 52767810, 52768143 |
NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 |
67847 |
40 |
nucleoplasm cytoplasm cell death ubiquitin protein ligase binding cytoplasmic ribonucleoprotein granule dopamine metabolic process identical protein binding regulation of neurotransmitter secretion regulation of inclusion body assembly |
05012 |
| TC1400000075.mm.2 |
Rpp14 |
ribonuclease P 14 subunit |
14 |
8080312 |
NM_025938, BC026988, BC046803 NM_025938, BC026988, BC046803 NM_025938, BC026988, BC046803 |
67053 |
20 |
tRNA 5'-leader removal ribonuclease P activity nucleolus multimeric ribonuclease P complex ribonuclease P RNA binding |
03013 |
| TC0800002235.mm.2 |
Neil3 |
nei like 3 (E. coli) |
8 |
-53586866 |
NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753 |
234258 |
34 |
bubble DNA binding nucleic acid binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding catalytic activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity nucleus nucleus nucleoplasm chromosome DNA repair base-excision repair base-excision repair base-excision repair nucleotide-excision repair cellular response to DNA damage stimulus metabolic process zinc ion binding hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds lyase activity DNA N-glycosylase activity DNA N-glycosylase activity DNA N-glycosylase activity metal ion binding |
03410 |
| TC0500000054.mm.2 |
Abcb4 |
ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
5 |
8893720 |
NM_008830, BC150687 NM_008830, BC150687 |
18670 |
156 |
Golgi membrane nucleotide binding ATP binding nucleoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane plasma membrane focal adhesion lipid transport actin cytoskeleton membrane integral component of membrane apical plasma membrane ATPase activity cytoplasmic vesicle positive regulation of cholesterol transport bile acid secretion ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity phospholipid translocation phospholipid translocation intercellular canaliculus transmembrane transport lipid homeostasis positive regulation of phospholipid translocation phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity ceramide floppase activity response to fenofibrate cellular response to bile acid positive regulation of phospholipid transport |
02010 04976 |
| TC1700000775.mm.2 |
Olfr110 |
olfactory receptor 110 |
17 |
37492467 |
NM_146328, BC132347 NM_146328, BC132347 |
258325 |
7 |
olfactory receptor activity G protein-coupled receptor signaling pathway sensory perception of smell integral component of membrane |
04740 |
| TC0400003000.mm.2 |
Hacd4 |
3-hydroxyacyl-CoA dehydratase 4 |
4 |
-88413955, -88410341 |
NM_025760, BC020155 NM_025760, BC020155 |
66775 |
13 |
endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity |
|
| TC1200002396.mm.2 |
Cinp |
cyclin-dependent kinase 2 interacting protein |
12 |
-110872609 |
NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 |
67236 |
17 |
molecular_function cellular_component nucleus DNA replication DNA repair cellular response to DNA damage stimulus cell cycle biological_process cell division |
|
| TC0700000652.mm.2 |
Cebpa |
CCAAT/enhancer binding protein (C/EBP), alpha |
7 |
35119292, 35119292 |
NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 |
12606 |
476 |
urea cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase I transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development embryonic placenta development DNA binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex nucleolus regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase I mitochondrion organization Notch signaling pathway multicellular organism development transcription factor binding transcription factor binding cholesterol metabolic process negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix cytokine-mediated signaling pathway kinase binding kinase binding protein domain specific binding myeloid cell differentiation myeloid cell differentiation macrophage differentiation lung development granulocyte differentiation granulocyte differentiation protein-containing complex Rb-E2F complex CHOP-C/EBP complex regulation of cell population proliferation glucose homeostasis identical protein binding protein homodimerization activity histone deacetylase binding positive regulation of macrophage activation intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding protein-containing complex binding fat cell differentiation fat cell differentiation fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation negative regulation of cell cycle negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III protein heterodimerization activity cell maturation inner ear development positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation lipid homeostasis interleukin-6-mediated signaling pathway cellular response to lithium ion cellular response to tumor necrosis factor cellular response to organic cyclic compound HMG box domain binding RNA polymerase II transcription regulator complex positive regulation of DNA-templated transcription, initiation |
05200 05221 |
| TC1500002012.mm.2 |
Cerk |
ceramide kinase |
15 |
-86139100 |
NM_145475, BC094253 NM_145475, BC094253 |
223753 |
42 |
nucleotide binding magnesium ion binding lipid kinase activity ceramide kinase activity ceramide kinase activity ceramide kinase activity ceramide kinase activity NAD+ kinase activity ATP binding cytoplasm mitochondrion plasma membrane sphingolipid metabolic process ceramide metabolic process ceramide metabolic process membrane integral component of membrane kinase activity phosphorylation transferase activity |
00600 |
| TC1900000727.mm.2 |
Gsto1 |
glutathione S-transferase omega 1 |
19 |
47854972 |
NM_010362, BC085165 NM_010362, BC085165 |
14873 |
36 |
glutathione transferase activity basement membrane nucleoplasm cytoplasm cytosol regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum oxidoreductase activity transferase activity L-ascorbic acid metabolic process L-ascorbic acid biosynthetic process axon nuclear membrane xenobiotic catabolic process myelin sheath cell body glutathione dehydrogenase (ascorbate) activity glutathione dehydrogenase (ascorbate) activity methylarsonate reductase activity negative regulation of ryanodine-sensitive calcium-release channel activity positive regulation of ryanodine-sensitive calcium-release channel activity cellular response to arsenic-containing substance |
00480 00980 00982 |
| TC0400002980.mm.2 |
Plin2 |
perilipin 2 |
4 |
-86656564 |
NM_007408, BC054766 NM_007408, BC054766 |
11520 |
135 |
protein binding nucleus cytoplasm lipid droplet lipid droplet lipid droplet cytosol cytosol plasma membrane positive regulation of sequestering of triglyceride long-chain fatty acid transport membrane lipid storage lipid storage |
|
| TC0200001760.mm.2 |
Rad51 |
RAD51 recombinase |
2 |
119112813 |
NM_011234, BC027384 NM_011234, BC027384 |
19361 |
173 |
recombinase activity nucleotide binding nuclear chromosome telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA recombinase assembly DNA recombinase assembly chromosome, telomeric region chromosome, telomeric region chromatin condensed chromosome condensed nuclear chromosome condensed nuclear chromosome synaptonemal complex lateral element lateral element regulation of protein phosphorylation DNA binding chromatin binding chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytoplasm mitochondrion cytoskeleton DNA metabolic process DNA unwinding involved in DNA replication DNA repair DNA recombination mitotic recombination cellular response to DNA damage stimulus cellular response to DNA damage stimulus reciprocal meiotic recombination reciprocal meiotic recombination protein C-terminus binding DNA-dependent ATPase activity regulation of double-strand break repair via homologous recombination telomere maintenance via telomere lengthening PML body single-stranded DNA helicase activity enzyme binding replication fork processing replication fork processing telomere organization protein-containing complex site of double-strand break interstrand cross-link repair strand invasion identical protein binding perinuclear region of cytoplasm positive regulation of DNA ligation meiotic cell cycle DNA polymerase binding chromosome organization involved in meiotic cell cycle chromosome organization involved in meiotic cell cycle cellular response to alkaloid cellular response to ionizing radiation cellular response to hydroxyurea cellular response to camptothecin replication-born double-strand break repair via sister chromatid exchange mitotic recombination-dependent replication fork processing |
03440 05200 05212 |
| TC1600001373.mm.2 |
Tmem41a |
transmembrane protein 41a |
16 |
-21934326 |
NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770 |
66664 |
13 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC0500002152.mm.2 |
Tyms |
thymidylate synthase |
5 |
-30058199 |
NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139 |
22171 |
38 |
translation repressor activity, mRNA regulatory element binding mRNA binding thymidylate synthase activity thymidylate synthase activity folic acid binding nucleus nucleolus cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix cytosol dTMP biosynthetic process dTMP biosynthetic process regulation of translation methyltransferase activity nucleotide biosynthetic process membrane transferase activity negative regulation of translation methylation tetrahydrofolate interconversion protein homodimerization activity heterocyclic compound binding sequence-specific mRNA binding |
00240 00670 01100 |
| TC0600001400.mm.2 |
Clec4b1 |
C-type lectin domain family 4, member b1 |
6 |
123049961 |
NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521 |
69810 |
15 |
positive regulation of release of sequestered calcium ion into cytosol |
|
| TC1600001143.mm.2 |
Ubald1 |
UBA-like domain containing 1 |
16 |
-4874778 |
NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081 |
207740 |
15 |
molecular_function cellular_component biological_process |
|
| TC1700001003.mm.2 |
Uhrf1 |
ubiquitin-like, containing PHD and RING finger domains, 1 |
17 |
56303336, 56304312 |
NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 |
18140 |
107 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin euchromatin heterochromatin heterochromatin cis-regulatory region sequence-specific DNA binding DNA binding ubiquitin-protein transferase activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork replication fork plasma membrane DNA repair chromatin organization ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus cell cycle zinc ion binding methyl-CpG binding maintenance of DNA methylation maintenance of DNA methylation maintenance of DNA methylation histone monoubiquitination histone monoubiquitination nuclear matrix protein ubiquitination histone ubiquitination transferase activity cytoplasmic vesicle nucleosomal histone binding positive regulation of cellular protein metabolic process methylated histone binding methylated histone binding histone binding identical protein binding hemi-methylated DNA-binding hemi-methylated DNA-binding metal ion binding regulation of epithelial cell proliferation protein autoubiquitination protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| TC0200002542.mm.2 |
Mmp9 |
matrix metallopeptidase 9 |
2 |
164948218 |
NM_013599, BC046991 NM_013599, BC046991 |
17395 |
1041 |
skeletal system development skeletal system development positive regulation of protein phosphorylation fibronectin binding positive regulation of leukocyte migration endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity extracellular region extracellular space proteolysis response to oxidative stress heart development embryo implantation aging peptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity transformation of host cell by virus extracellular matrix organization extracellular matrix organization extracellular matrix organization positive regulation of cell migration collagen catabolic process collagen catabolic process collagen catabolic process extracellular matrix positive regulation of synaptic plasticity protein-containing complex cellular response to reactive oxygen species response to drug identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding protein-containing complex binding positive regulation of epidermal growth factor receptor signaling pathway positive regulation of angiogenesis metal ion binding negative regulation of fibroblast proliferation tissue remodeling positive regulation of keratinocyte migration collagen-containing extracellular matrix cellular response to cadmium ion cellular response to cell-matrix adhesion cellular response to UV-A positive regulation of release of cytochrome c from mitochondria positive regulation of receptor binding response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of epithelial cell differentiation involved in kidney development negative regulation of intrinsic apoptotic signaling pathway negative regulation of cation channel activity negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
04670 05200 05219 |
| TC1100004183.mm.2 |
Sgsh |
N-sulfoglucosamine sulfohydrolase (sulfamidase) |
11 |
-119343488 |
NM_018822, BC130268 NM_018822, BC130268 |
27029 |
46 |
protein binding glycosaminoglycan binding lysosome lysosome glycosaminoglycan catabolic process glycosaminoglycan catabolic process N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity sulfuric ester hydrolase activity N-sulfoglucosamine sulfohydrolase activity N-sulfoglucosamine sulfohydrolase activity heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan metabolic process |
00531 01100 04142 |
| TC1600001262.mm.2 |
Fgd4 |
FYVE, RhoGEF and PH domain containing 4 |
16 |
-16416914, -16416914, -16416914 |
NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 NM_139232, BC129902, BC129903, NM_139233, NM_139234 |
224014 |
30 |
actin binding guanyl-nucleotide exchange factor activity cytoplasm cytoskeleton cytoskeleton organization activation of JUN kinase activity regulation of cell shape lamellipodium lamellipodium assembly microspike assembly filopodium regulation of Rho protein signal transduction cell projection filopodium assembly metal ion binding actin filament binding |
|
| TC0700002617.mm.2 |
Atp1a3 |
ATPase, Na+/K+ transporting, alpha 3 polypeptide |
7 |
-24978168, -24978168 |
BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 |
232975 |
83 |
nucleotide binding amyloid-beta binding photoreceptor inner segment P-type sodium:potassium-exchanging ATPase activity P-type sodium:potassium-exchanging ATPase activity ATP binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex ion transport potassium ion transport sodium ion transport cellular sodium ion homeostasis cellular sodium ion homeostasis cellular sodium ion homeostasis memory adult locomotory behavior visual learning potassium transmembrane transporter activity, phosphorylative mechanism membrane integral component of membrane cellular potassium ion homeostasis cellular potassium ion homeostasis axon organelle membrane D1 dopamine receptor binding ionotropic glutamate receptor signaling pathway sodium ion export across plasma membrane sodium ion export across plasma membrane sodium ion export across plasma membrane sarcolemma response to drug neuronal cell body myelin sheath myelin sheath heparan sulfate proteoglycan binding calyx of Held dendritic spine neck dendritic spine head synapse metal ion binding chaperone binding cardiac muscle contraction regulation of cardiac muscle cell membrane potential sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential postsynapse neuron to neuron synapse integral component of presynaptic membrane ion antiporter activity involved in regulation of presynaptic membrane potential proton transmembrane transport cellular response to amyloid-beta neuron projection maintenance potassium ion import across plasma membrane potassium ion import across plasma membrane |
04260 04960 04964 04970 04971 04972 04973 04974 04976 |
| TC0300000491.mm.2 |
P2ry1 |
purinergic receptor P2Y, G-protein coupled 1 |
3 |
61002784 |
NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 |
18441 |
114 |
nucleotide binding G protein-coupled ADP receptor activity positive regulation of protein phosphorylation G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor activity ATP binding mitochondrion plasma membrane plasma membrane integral component of plasma membrane cilium signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration glial cell migration regulation of cell shape response to mechanical stimulus regulation of signaling receptor activity negative regulation of norepinephrine secretion postsynaptic density membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain signal transduction involved in regulation of gene expression platelet activation dendrite A1 adenosine receptor binding positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway eating behavior positive regulation of ion transport positive regulation of ion transport ADP binding cell body G protein-coupled purinergic nucleotide receptor activity G protein-coupled ATP receptor activity postsynaptic membrane positive regulation of transcription by RNA polymerase II positive regulation of hormone secretion protein heterodimerization activity negative regulation of binding positive regulation of penile erection positive regulation of ERK1 and ERK2 cascade cellular response to organic cyclic compound cellular response to purine-containing compound protein localization to plasma membrane relaxation of muscle scaffold protein binding blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis |
04080 |
| TC1300000245.mm.2 |
H2ac10 |
H2A clustered histone 10 |
13 |
23533874 |
NM_175661, BC125011 NM_175661, BC125011 |
319173 |
10 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC1000002341.mm.2 |
Cdk1 |
cyclin-dependent kinase 1 |
10 |
-69335145 |
NM_007659, BC024396 NM_007659, BC024396 |
12534 |
223 |
G2/M transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix centrosome cytosol cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint cell aging cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity response to organonitrogen compound positive regulation of gene expression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation chromosome condensation cyclin binding midbody Hsp70 protein binding animal organ regeneration protein localization to kinetochore histone kinase activity positive regulation of protein import into nucleus regulation of circadian rhythm negative regulation of apoptotic process mitotic cell cycle phase transition response to ethanol positive regulation of DNA replication positive regulation of mitotic cell cycle rhythmic process cell division positive regulation of cardiac muscle cell proliferation protein-containing complex assembly mitotic spindle Golgi disassembly cyclin B1-CDK1 complex cyclin-dependent protein kinase activity positive regulation of protein localization to nucleus positive regulation of mitochondrial ATP synthesis coupled electron transport |
04110 04114 04115 04540 04914 |
| TC0500001663.mm.2 |
Fam20c |
FAM20C, golgi associated secretory pathway kinase |
5 |
138755080 |
NM_030565 |
80752 |
44 |
nucleotide binding skeletal system development protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity calcium ion binding ATP binding extracellular region extracellular space extracellular space extracellular space cytoplasm cytoplasm Golgi apparatus Golgi apparatus protein phosphorylation protein phosphorylation protein phosphorylation kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor manganese ion binding positive regulation of bone mineralization biomineral tissue development osteoclast maturation regulation of fibroblast growth factor receptor signaling pathway positive regulation of osteoblast differentiation ATP metabolic process metal ion binding regulation of phosphorus metabolic process enamel mineralization enamel mineralization odontoblast differentiation dentinogenesis |
|
| TC1500000432.mm.2 |
Sqle |
squalene epoxidase |
15 |
59315091 |
NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361 |
20775 |
31 |
squalene monooxygenase activity squalene monooxygenase activity endoplasmic reticulum cellular aromatic compound metabolic process cholesterol metabolic process cholesterol metabolic process response to organic substance membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process oxidoreductase activity regulation of cell population proliferation intracellular membrane-bounded organelle flavin adenine dinucleotide binding FAD binding lipid droplet formation |
00100 01100 |
| TC1600001191.mm.2 |
Emp2 |
epithelial membrane protein 2 |
16 |
-10281748 |
NM_007929, BC041670 NM_007929, BC041670 |
13731 |
31 |
membrane raft assembly T cell mediated cytotoxicity regulation of cell-matrix adhesion regulation of cell-matrix adhesion positive regulation of cell-matrix adhesion regulation of glomerular filtration integrin binding integrin binding nucleus cytoplasm cytoplasm cytoplasm Golgi apparatus plasma membrane plasma membrane actin filament organization cell adhesion cell adhesion cell-matrix adhesion embryo implantation embryo implantation cell death positive regulation of cell population proliferation cell surface regulation of endothelial cell migration membrane integral component of membrane apical plasma membrane cell migration kinase binding protein kinase binding protein kinase binding cytoplasmic vesicle bleb assembly activation of protein kinase activity protein localization to cell surface blood vessel endothelial cell migration regulation of kinase activity early endosome to late endosome transport membrane raft membrane raft apical part of cell regulation of angiogenesis actin-mediated cell contraction protein localization to plasma membrane positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway regulation of vasculogenesis |
|
| TC0900002503.mm.2 |
Hacd3 |
3-hydroxyacyl-CoA dehydratase 3 |
9 |
-64986982 |
NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023 |
57874 |
26 |
protein binding endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process I-kappaB kinase/NF-kappaB signaling JNK cascade Rho protein signal transduction membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation nuclear membrane very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process positive regulation of viral genome replication positive regulation by virus of viral protein levels in host cell 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity |
|
| TC1300000572.mm.2 |
Iars |
isoleucine-tRNA synthetase |
13 |
49682129 |
NM_172015, BC067029 NM_172015, BC067029 |
105148 |
26 |
tRNA binding nucleotide binding aminoacyl-tRNA editing activity aminoacyl-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity ATP binding nucleoplasm cytoplasm cytosol translation tRNA aminoacylation for protein translation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex GTPase binding |
00290 00970 |
| TC1000002264.mm.2 |
Ddx21 |
DExD box helicase 21 |
10 |
-62580246 |
NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237 |
56200 |
47 |
nucleotide binding immune system process positive regulation of myeloid dendritic cell cytokine production nucleic acid binding RNA binding RNA binding RNA helicase activity RNA helicase activity RNA helicase activity double-stranded RNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus cytoplasm mitochondrion cytosol rRNA processing transcription by RNA polymerase II response to virus hydrolase activity rRNA binding snoRNA binding miRNA binding identical protein binding positive regulation of I-kappaB kinase/NF-kappaB signaling response to exogenous dsRNA innate immune response defense response to virus R-loop disassembly 7SK snRNA binding |
|
| TC0800000959.mm.2 |
Lyl1 |
lymphoblastomic leukemia 1 |
8 |
84701456 |
NM_008535, BC005736 NM_008535, BC005736 |
17095 |
45 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific blood vessel maturation DNA binding nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II B cell differentiation positive regulation of transcription, DNA-templated protein dimerization activity definitive hemopoiesis |
|
| TC1700000036.mm.2 |
Zdhhc14 |
zinc finger, DHHC domain containing 14 |
17 |
5492599 |
NM_146073, BC059814 NM_146073, BC059814 |
224454 |
19 |
endoplasmic reticulum endoplasmic reticulum Golgi apparatus protein targeting to membrane membrane integral component of membrane palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity |
|
| TC0200004410.mm.2 |
Gpr176 |
G protein-coupled receptor 176 |
2 |
-118277097 |
NM_201367, BC052037 NM_201367, BC052037 |
381413 |
18 |
G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway membrane integral component of membrane rhythmic process circadian behavior |
|
| TC1100000582.mm.2 |
Cdkn2aipnl |
CDKN2A interacting protein N-terminal like |
11 |
51967630 |
NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363 |
52626 |
20 |
molecular_function nucleoplasm nucleolus |
|
| TC1800001048.mm.2 |
B4galt6 |
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 |
18 |
-20684598 |
NM_019737, BC011149 NM_019737, BC011149 |
56386 |
28 |
lactosylceramide biosynthetic process cellular_component Golgi apparatus Golgi apparatus carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process glycosphingolipid biosynthetic process glycosphingolipid biosynthetic process galactosyltransferase activity galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity ganglioside biosynthetic process via lactosylceramide membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups central nervous system neuron axonogenesis central nervous system myelination sphingolipid biosynthetic process neuron maturation metal ion binding glycosylation |
00600 01100 |
| TC1100000983.mm.2 |
Pimreg |
PICALM interacting mitotic regulator |
11 |
72042501 |
NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115 |
109212 |
18 |
molecular_function nucleus nucleoplasm nucleolus cell cycle cell division |
|
| TC1600000480.mm.2 |
Itgb5 |
integrin beta 5 |
16 |
33829664 |
NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 |
16419 |
91 |
signaling receptor binding integrin binding integrin binding protein binding plasma membrane focal adhesion focal adhesion cell adhesion cell-matrix adhesion cell-matrix adhesion transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin complex cell surface cell surface membrane integral component of membrane cell migration cell leading edge cell adhesion mediated by integrin integrin alphav-beta5 complex integrin alphav-beta5 complex signaling receptor activity stress fiber assembly stress fiber assembly receptor complex epithelial cell-cell adhesion glutamatergic synapse integral component of synaptic membrane |
04145 04510 04512 04810 05410 05412 05414 |
| TC1800001404.mm.2 |
Ndst1 |
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
18 |
-60684493, -60684493, -60684493, -60701433, -60684493, -60684493 |
NM_008306, BC066098, BC079561 NM_008306, BC066098, BC079561 NM_008306, BC066098, BC079561 |
15531 |
88 |
polysaccharide biosynthetic process cardiac septum development catalytic activity protein binding Golgi apparatus protein deacetylation protein sulfation protein sulfation inflammatory response heart development respiratory gaseous exchange by respiratory system sulfotransferase activity metabolic process cell population proliferation fibroblast growth factor receptor signaling pathway embryo development animal organ morphogenesis heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [heparan sulfate]-glucosamine N-sulfotransferase activity [heparan sulfate]-glucosamine N-sulfotransferase activity [heparan sulfate]-glucosamine N-sulfotransferase activity membrane integral component of membrane transferase activity hydrolase activity deacetylase activity deacetylase activity glycosaminoglycan metabolic process forebrain development forebrain development midbrain development aorta development positive regulation of MAPK cascade positive regulation of smoothened signaling pathway embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis coronary vasculature development heparan sulfate N-deacetylase activity |
00534 01100 |
| TC0200001776.mm.2 |
Nusap1 |
nucleolar and spindle associated protein 1 |
2 |
119618297 |
NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 |
108907 |
31 |
mitotic sister chromatid segregation microtubule cytoskeleton organization mitotic cytokinesis mitotic cytokinesis DNA binding nucleus chromosome nucleolus nucleolus cytoplasm spindle cytoskeleton microtubule cell cycle mitotic chromosome condensation mitotic chromosome condensation microtubule binding microtubule binding establishment of mitotic spindle localization establishment of mitotic spindle localization positive regulation of mitotic nuclear division cell division mitotic spindle |
|
| TC0400001217.mm.2 |
Pdzk1ip1 |
PDZK1 interacting protein 1 |
4 |
115088707 |
NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 |
67182 |
24 |
molecular_function biological_process membrane integral component of membrane |
|
| TC1100001155.mm.2 |
Spag5 |
sperm associated antigen 5 |
11 |
78301590 |
NM_017407, BC052672 NM_017407, BC052672 |
54141 |
31 |
mitotic sister chromatid segregation chromosome, centromeric region kinetochore chromosome cytoplasm spindle cytosol cytoskeleton microtubule cell cycle spindle organization chromosome segregation microtubule binding nuclear body positive regulation of intracellular transport centriolar satellite microtubule plus-end establishment of spindle orientation cell division regulation of attachment of spindle microtubules to kinetochore protein localization to centrosome mitotic spindle mitotic spindle regulation of metaphase plate congression mitotic spindle pole positive regulation of spindle assembly |
|
| TC0200001144.mm.2 |
Gm14461 |
predicted gene 14461 |
2 |
78237546 |
NM_177843 |
329436 |
10 |
|
|
| TC0700001756.mm.2 |
Prkcb |
protein kinase C, beta |
7 |
122289124 |
NM_008855, BC127083 NM_008855, BC127083 |
18751 |
222 |
nucleotide binding response to hypoxia adaptive immune response immune system process chromatin binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein kinase C activity protein kinase C activity protein kinase C binding calcium channel regulator activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm centrosome cytosol plasma membrane chromatin organization regulation of transcription by RNA polymerase II protein phosphorylation calcium ion transport cellular calcium ion homeostasis apoptotic process spectrin zinc ion binding regulation of glucose transmembrane transport negative regulation of glucose transmembrane transport regulation of dopamine secretion membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation nuclear receptor coactivator activity positive regulation of vascular endothelial growth factor receptor signaling pathway brush border membrane histone kinase activity (H3-T6 specific) histone H3-T6 phosphorylation intracellular signal transduction regulation of growth B cell activation histone binding response to drug positive regulation of I-kappaB kinase/NF-kappaB signaling calyx of Held calyx of Held positive regulation of angiogenesis negative regulation of insulin receptor signaling pathway metal ion binding androgen receptor binding B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity cellular response to carbohydrate stimulus presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission presynaptic cytosol regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis |
04010 04012 04020 04062 04070 04270 04310 04370 04510 04530 04540 04650 04662 04664 04666 04670 04720 04730 04912 04916 04960 04970 04971 04972 04973 05140 05143 05146 05200 05214 05223 |
| TC0X00003021.mm.2 |
Tceal8 |
transcription elongation factor A (SII)-like 8 |
X |
-136168983 |
NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269 |
66684 |
18 |
nucleus WW domain binding |
|
| TC0100002736.mm.2 |
Htr2b |
5-hydroxytryptamine (serotonin) receptor 2B |
1 |
-86099036 |
NM_008311, BC023690 NM_008311, BC023690 |
15559 |
104 |
Gq/11-coupled serotonin receptor activity neural crest cell migration positive regulation of cytokine production positive regulation of cytokine production positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation G-protein alpha-subunit binding G protein-coupled receptor internalization heart morphogenesis cardiac muscle hypertrophy G protein-coupled receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity G protein-coupled serotonin receptor activity GTPase activator activity nucleoplasm cytoplasm cytoplasm plasma membrane plasma membrane integral component of plasma membrane cellular calcium ion homeostasis smooth muscle contraction signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger phospholipase C-activating G protein-coupled receptor signaling pathway activation of phospholipase C activity protein kinase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating serotonin receptor signaling pathway phospholipase C-activating serotonin receptor signaling pathway chemical synaptic transmission heart development behavior positive regulation of cell population proliferation negative regulation of autophagy positive regulation of phosphatidylinositol biosynthetic process neural crest cell differentiation phosphatidylinositol 3-kinase signaling intestine smooth muscle contraction membrane integral component of membrane phosphorylation calcium-mediated signaling cGMP-mediated signaling cell junction dendrite dendrite neurotransmitter receptor activity ion transmembrane transport vasoconstriction response to drug response to drug neuron projection neuronal cell body negative regulation of apoptotic process positive regulation of MAP kinase activity synapse embryonic morphogenesis regulation of behavior regulation of behavior positive regulation of nitric-oxide synthase activity release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol serotonin binding serotonin binding positive regulation of cell division negative regulation of cell death ERK1 and ERK2 cascade ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade protein kinase C signaling cellular response to amine stimulus cellular response to temperature stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled serotonin receptor complex G protein-coupled serotonin receptor complex cellular response to serotonin |
04020 04080 04540 |
| TC0400002275.mm.2 |
Atp6v0d2 |
ATPase, H+ transporting, lysosomal V0 subunit D2 |
4 |
-19876837 |
NM_175406, BC087899 NM_175406, BC087899 |
242341 |
45 |
lysosomal membrane endosome early endosome early endosome ion transport vacuolar transport vacuolar acidification proton transmembrane transporter activity membrane apical plasma membrane vacuolar proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V0 domain plasma membrane proton-transporting V-type ATPase complex proton-transporting ATPase activity, rotational mechanism proton transmembrane transport |
00190 01100 04142 04145 04966 05323 |
| TC1700001969.mm.2 |
Tcf19 |
transcription factor 19 |
17 |
-35512734 |
NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 |
106795 |
29 |
G1/S transition of mitotic cell cycle nucleus nucleus regulation of gene expression regulation of gene expression type B pancreatic cell proliferation |
|
| TC1400000350.mm.2 |
Tmem273 |
transmembrane protein 273 |
14 |
32785962 |
NM_001163616 |
69069 |
8 |
molecular_function cellular_component biological_process |
|
| TC0400001312.mm.2 |
|
|
|
|
NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 |
|
|
nucleus chromosome nucleolus nucleolus rRNA processing preribosome, large subunit precursor nuclear periphery ribosome biogenesis ribosomal large subunit biogenesis |
|
| TC1900001240.mm.2 |
Anxa1 |
annexin A1 |
19 |
-20373433 |
NM_010730, BC002289, BC004594 NM_010730, BC002289, BC004594 NM_010730, BC002289, BC004594 |
16952 |
210 |
cornified envelope neutrophil homeostasis neutrophil homeostasis adaptive immune response immune system process monocyte chemotaxis regulation of leukocyte migration regulation of leukocyte migration single-stranded DNA binding single-stranded RNA binding phospholipase inhibitor activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding extracellular region extracellular space extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm endosome cytosol cytosol actin filament plasma membrane plasma membrane plasma membrane cilium phagocytosis inflammatory response inflammatory response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of cell shape regulation of cell shape cell surface response to X-ray myoblast migration involved in skeletal muscle regeneration myoblast migration involved in skeletal muscle regeneration membrane apical plasma membrane lateral plasma membrane peptide cross-linking phospholipase A2 inhibitor activity phospholipase A2 inhibitor activity extrinsic component of membrane insulin secretion insulin secretion keratinocyte differentiation keratinocyte differentiation prostate gland development endocrine pancreas development extrinsic component of external side of plasma membrane positive regulation of vesicle fusion positive regulation of vesicle fusion positive regulation of prostaglandin biosynthetic process positive regulation of prostaglandin biosynthetic process cytoplasmic vesicle motile cilium actin cytoskeleton reorganization actin cytoskeleton reorganization mitochondrial membrane response to estradiol DNA duplex unwinding DNA duplex unwinding regulation of interleukin-1 production regulation of interleukin-1 production negative regulation of interleukin-8 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production protein-containing complex positive regulation of neutrophil apoptotic process positive regulation of neutrophil apoptotic process cellular response to vascular endothelial growth factor stimulus cellular response to vascular endothelial growth factor stimulus double-stranded DNA helicase activity gliogenesis positive regulation of T cell proliferation positive regulation of T cell proliferation regulation of cell population proliferation sarcolemma response to drug mast cell granule identical protein binding cell projection positive regulation of apoptotic process response to peptide hormone estrous cycle innate immune response positive regulation of T-helper 1 cell differentiation positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis negative regulation of exocytosis alpha-beta T cell differentiation alpha-beta T cell differentiation metal ion binding regulation of hormone secretion regulation of hormone secretion calcium-dependent protein binding arachidonic acid secretion arachidonic acid secretion negative regulation of protein secretion regulation of inflammatory response regulation of inflammatory response collagen-containing extracellular matrix extracellular exosome cellular response to hydrogen peroxide cellular response to hydrogen peroxide hepatocyte differentiation prolactin secretion prolactin secretion response to interleukin-1 cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus granulocyte chemotaxis granulocyte chemotaxis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of wound healing positive regulation of wound healing synaptic membrane neutrophil clearance neutrophil clearance positive regulation of G1/S transition of mitotic cell cycle positive regulation of G1/S transition of mitotic cell cycle negative regulation of phospholipase A2 activity negative regulation of phospholipase A2 activity DNA/DNA annealing activity |
|
| TC0600001397.mm.2 |
Clec4a1 |
C-type lectin domain family 4, member a1 |
6 |
122921847 |
NM_199311, BC049354 NM_199311, BC049354 |
269799 |
5 |
molecular_function cellular_component biological_process |
|
| TC1600001379.mm.2 |
Etv5 |
ets variant 5 |
16 |
-22381312, -22381312 |
NM_023794, BC034680 NM_023794, BC034680 |
104156 |
283 |
negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II neuromuscular synaptic transmission locomotory behavior cell differentiation cellular response to oxidative stress sequence-specific DNA binding positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II male germ-line stem cell asymmetric division regulation of synapse organization positive regulation of glial cell proliferation regulation of branching involved in mammary gland duct morphogenesis skeletal muscle acetylcholine-gated channel clustering sequence-specific double-stranded DNA binding |
|
| TC0100000590.mm.2 |
Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
1 |
71557155 |
NM_026195, BC039925 NM_026195, BC039925 |
108147 |
24 |
catalytic activity IMP cyclohydrolase activity IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity mitochondrion cytosol cytosol plasma membrane purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process 'de novo' IMP biosynthetic process metabolic process nucleoside metabolic process ribonucleotide metabolic process transferase activity hydrolase activity protein homodimerization activity dihydrofolate metabolic process tetrahydrofolate biosynthetic process cellular response to interleukin-7 |
00230 00670 01100 |
| TC1300001562.mm.2 |
H2ac22 |
H2A clustered histone 22 |
13 |
-21786773 |
NM_178184 |
319170 |
4 |
DNA binding nucleus chromatin silencing enzyme binding |
05322 |
| TC0300002718.mm.2 |
Csf1 |
colony stimulating factor 1 (macrophage) |
3 |
-107745594, -107741047 |
NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 NM_001113529, NM_001113530, NM_007778, BC066187, BC066200, BC066205 |
12977 |
508 |
ossification positive regulation of cell-matrix adhesion osteoclast proliferation immune system process response to ischemia developmental process involved in reproduction cytokine activity cytokine activity macrophage colony-stimulating factor receptor binding protein binding extracellular region extracellular space extracellular space extracellular space plasma membrane inflammatory response transmembrane receptor protein tyrosine kinase signaling pathway growth factor activity cell population proliferation positive regulation of cell population proliferation positive regulation of gene expression positive regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of macrophage chemotaxis membrane integral component of membrane nuclear body macrophage differentiation regulation of ossification osteoclast differentiation osteoclast differentiation osteoclast differentiation positive regulation of cell migration positive regulation of cellular protein metabolic process positive regulation of mononuclear cell proliferation macrophage colony-stimulating factor signaling pathway positive regulation of multicellular organism growth odontogenesis positive regulation of odontogenesis of dentin-containing tooth identical protein binding identical protein binding protein homodimerization activity protein homodimerization activity innate immune response positive regulation of macrophage differentiation positive regulation of macrophage differentiation positive regulation of macrophage differentiation positive regulation of monocyte differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of protein kinase activity positive regulation of Ras protein signal transduction perinuclear region of cytoplasm homeostasis of number of cells within a tissue branching involved in mammary gland duct morphogenesis mammary gland fat development mammary duct terminal end bud growth microglial cell proliferation negative regulation of neuron death positive regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell migration CSF1-CSF1R complex |
04060 04380 04640 05323 |
| TC0600001474.mm.2 |
D6Wsu163e |
DNA segment, Chr 6, Wayne State University 163, expressed |
6 |
126939965 |
NM_138594, BC016429 NM_138594, BC016429 |
28040 |
17 |
molecular_function cytoplasm cytoplasm regulation of mast cell degranulation regulation of mast cell degranulation |
|
| TC0500000888.mm.2 |
Septin11 |
septin 11 |
5 |
93093415, 93093415 |
NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 |
52398 |
38 |
nucleotide binding stress fiber GTPase activity protein binding GTP binding cytoplasm cytoskeleton septin ring cell cycle microtubule cytoskeleton cell junction septin complex septin complex septin complex cell division site cellular protein localization cell projection synapse regulation of synapse organization cell division molecular adaptor activity cytoskeleton-dependent cytokinesis postsynapse glutamatergic synapse GABA-ergic synapse postsynaptic specialization of symmetric synapse |
|
| TC1100003771.mm.2 |
Nt5c3b |
5'-nucleotidase, cytosolic IIIB |
11 |
-100429351, -100439552, -100422320 |
NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307 |
68106 |
15 |
nucleotide binding magnesium ion binding cytoplasm nucleotide metabolic process hydrolase activity metal ion binding |
|
| TC1900000748.mm.2 |
Add3 |
adducin 3 (gamma) |
19 |
53140442, 53142755, 53143996 |
NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 |
27360 |
31 |
condensed nuclear chromosome actin binding protein kinase C binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton cytoskeleton plasma membrane brush border cell-cell junction cell cortex postsynaptic density postsynaptic density membrane response to drug positive regulation of vasoconstriction actin filament binding barbed-end actin filament capping |
|
| TC1300001069.mm.2 |
Wdr41 |
WD repeat domain 41 |
13 |
94976343 |
NM_172590, BC138095, BC145144 NM_172590, BC138095, BC145144 NM_172590, BC138095, BC145144 |
218460 |
18 |
guanyl-nucleotide exchange factor activity cytoplasm cytoplasm autophagy regulation of autophagy guanyl-nucleotide exchange factor complex Atg1/ULK1 kinase complex |
|
| TC1900000560.mm.2 |
Hells |
helicase, lymphoid specific |
19 |
38930989 |
NM_008234, BC100394 NM_008234, BC100394 |
15201 |
65 |
nucleotide binding chromosome, centromeric region urogenital system development chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus pericentric heterochromatin pericentric heterochromatin DNA methylation DNA methylation chromatin silencing DNA methylation-dependent heterochromatin assembly DNA methylation-dependent heterochromatin assembly cell cycle multicellular organism development maintenance of DNA methylation maintenance of DNA methylation hydrolase activity lymphocyte differentiation pericentric heterochromatin assembly pericentric heterochromatin assembly negative regulation of apoptotic process lymphocyte proliferation lymphocyte proliferation cell division cellular response to leukemia inhibitory factor negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0100000836.mm.2 |
|
|
|
|
NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 NM_013701, NM_145079, NM_201410, NM_201641, NM_201642, NM_201643, NM_201644, NM_201645, BC026561, BC069940, BC089569, BC093516, BC138676, BC138699, BC139093, BC139094, BC141205, BC141206, BC145969, BC146021, BC165969 |
|
|
retinoic acid binding enzyme inhibitor activity protein kinase C binding steroid binding fatty acid binding mitochondrial inner membrane endoplasmic reticulum integral component of plasma membrane estrogen catabolic process drug binding estrogen metabolic process response to organic substance glucuronosyltransferase activity glucuronosyltransferase activity membrane membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups aromatic compound catabolic process glucuronate metabolic process glucuronate metabolic process enzyme binding bile acid secretion protein-containing complex endoplasmic reticulum chaperone complex protein homodimerization activity intracellular membrane-bounded organelle intracellular membrane-bounded organelle protein-containing complex binding coumarin catabolic process protein heterodimerization activity flavone metabolic process cellular glucuronidation flavonoid glucuronidation flavonoid glucuronidation xenobiotic glucuronidation xenobiotic glucuronidation cytochrome complex vitamin D3 metabolic process biphenyl catabolic process negative regulation of cellular glucuronidation |
|
| TC1400002836.mm.2 |
Dok2 |
docking protein 2 |
14 |
70774380 |
NM_010071, BC004590 NM_010071, BC004590 |
13449 |
54 |
transmembrane receptor protein tyrosine kinase adaptor activity protein binding transmembrane receptor protein tyrosine kinase signaling pathway Ras protein signal transduction negative regulation of MAPK cascade |
|
| TC0100001227.mm.2 |
Cyb5r1 |
cytochrome b5 reductase 1 |
1 |
134405780 |
NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618 |
72017 |
21 |
cytochrome-b5 reductase activity, acting on NAD(P)H mitochondrion lipid metabolic process steroid biosynthetic process steroid metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity FAD binding |
00520 |
| TC1900000171.mm.2 |
|
|
|
|
NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 NM_001039959, NM_001286518, NM_009643, NR_104460, NR_105786 |
|
|
protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction actin cytoskeleton actin cytoskeleton vesicle vesicle sarcolemma identical protein binding costamere costamere regulation of RNA splicing regulation of RNA splicing cell-cell contact zone cell-cell contact zone S100 protein binding membrane raft membrane raft extracellular exosome structural molecule activity conferring elasticity regulation of voltage-gated calcium channel activity |
|
| TC1200001314.mm.2 |
Rapgef5 |
Rap guanine nucleotide exchange factor (GEF) 5 |
12 |
117516525, 117533927 |
NM_175930, BC046627 NM_175930, BC046627 |
217944 |
25 |
guanyl-nucleotide exchange factor activity intracellular anatomical structure nucleus nucleoplasm small GTPase mediated signal transduction nuclear body GTP-dependent protein binding intracellular signal transduction |
|
| TC0700001122.mm.2 |
Fanci |
Fanconi anemia, complementation group I |
7 |
79392337 |
NM_145946 |
208836 |
25 |
nucleus nucleoplasm cytoplasm cytosol DNA repair cellular response to DNA damage stimulus cell cycle positive regulation of protein ubiquitination Fanconi anaemia nuclear complex DNA polymerase binding DNA polymerase binding |
|
| TC0200005052.mm.2 |
Mafb |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) |
2 |
-160363676 |
NM_010658, BC016434, BC038256 NM_010658, BC016434, BC038256 NM_010658, BC016434, BC038256 |
16658 |
255 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II segment specification respiratory gaseous exchange by respiratory system transcription factor binding rhombomere 5 development rhombomere 6 development abducens nerve formation T cell differentiation in thymus brain segmentation inner ear morphogenesis identical protein binding sequence-specific DNA binding protein-containing complex binding regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation negative regulation of osteoclast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development sequence-specific double-stranded DNA binding |
|
| TC0700002950.mm.2 |
Cd33 |
CD33 antigen |
7 |
-43527455 |
NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 |
12489 |
24 |
plasma membrane cell adhesion external side of plasma membrane membrane integral component of membrane carbohydrate binding sialic acid binding |
04640 |
| TC0300003225.mm.2 |
|
|
|
|
BC145417, BC145418, NM_001173459 BC145417, BC145418, NM_001173459 BC145417, BC145418, NM_001173459 |
|
|
molecular_function plasma membrane plasma membrane intracellular signal transduction positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of T cell activation |
|
| TC0100002974.mm.2 |
Ddx18 |
DEAD box helicase 18 |
1 |
-121553834 |
NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 |
66942 |
25 |
nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleic acid binding RNA binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus hydrolase activity |
|
| TC0100000682.mm.2 |
|
|
|
|
NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 |
|
|
nucleotide binding long-chain fatty acid metabolic process long-chain fatty acid metabolic process catalytic activity long-chain fatty acid-CoA ligase activity long-chain fatty acid-CoA ligase activity ATP binding nucleus nucleolus nucleolus mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum endoplasmic reticulum Golgi apparatus lipid droplet lipid droplet cytosol plasma membrane rRNA processing lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development spermatogenesis membrane integral component of membrane ligase activity protein kinase binding protein domain specific binding cell differentiation neuron differentiation small-subunit processome very-low-density lipoprotein particle assembly long-chain fatty-acyl-CoA metabolic process ribosome biogenesis positive regulation of Golgi to plasma membrane protein transport intracellular membrane-bounded organelle long-chain fatty acid import into cell arachidonate-CoA ligase activity perinuclear region of cytoplasm positive regulation of secretion meiotic cell cycle decanoate-CoA ligase activity positive regulation of phosphatidylcholine biosynthetic process |
|
| TC0X00002993.mm.2 |
Timm8a1 |
translocase of inner mitochondrial membrane 8A1 |
X |
11609223, -134537255 |
NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631 |
30058 |
26 |
mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space protein targeting to mitochondrion zinc ion binding protein transport membrane identical protein binding metal ion binding chaperone-mediated protein transport |
|
| TC0200004568.mm.2 |
Bub1 |
BUB1, mitotic checkpoint serine/threonine kinase |
2 |
-127800199 |
NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116 |
12235 |
63 |
nucleotide binding chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed nuclear chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm chromosome cytosol protein phosphorylation apoptotic process cell cycle chromosome segregation regulation of sister chromatid cohesion mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity intracellular membrane-bounded organelle cell division meiotic sister chromatid cohesion, centromeric regulation of chromosome segregation mitotic spindle checkpoint positive regulation of intrinsic apoptotic signaling pathway |
04110 04114 04914 |
| TC0700001151.mm.2 |
Prc1 |
protein regulator of cytokinesis 1 |
7 |
80294475, 80294450 |
NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 |
233406 |
44 |
microtubule cytoskeleton organization cytokinesis microtubule bundle formation nucleus nucleoplasm cytoplasm spindle spindle cytoskeleton microtubule plasma membrane cell cycle microtubule binding positive regulation of cell population proliferation microtubule cytoskeleton kinesin binding protein kinase binding midbody regulation of cytokinesis identical protein binding intercellular bridge mitotic spindle midzone assembly cell division contractile ring mitotic spindle midzone |
|
| TC1800000265.mm.2 |
Wdr36 |
WD repeat domain 36 |
18 |
32837224, 32837224, 32837224 |
NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 |
225348 |
24 |
retina homeostasis nucleolus rRNA processing regulation of axon extension small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC0100000222.mm.2 |
Imp4 |
IMP4, U3 small nucleolar ribonucleoprotein |
1 |
34439828 |
NM_178601, BC069930 NM_178601, BC069930 |
27993 |
20 |
fibrillar center nucleus nucleolus nucleolus rRNA processing snoRNA binding preribosome small-subunit processome Mpp10 complex Mpp10 complex ribosome biogenesis |
03008 |
| TC1600001527.mm.2 |
Umps |
uridine monophosphate synthetase |
16 |
-33954781 |
NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981 |
22247 |
30 |
catalytic activity orotate phosphoribosyltransferase activity orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity orotidine-5'-phosphate decarboxylase activity nucleus cytoplasm 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process UMP biosynthetic process metabolic process nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups lyase activity carboxy-lyase activity pyrimidine nucleobase biosynthetic process identical protein binding 'de novo' UMP biosynthetic process |
00240 00983 01100 |
| TC0200003717.mm.2 |
Mettl8 |
methyltransferase like 8 |
2 |
-70964560, -70964561 |
NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 |
228019 |
18 |
histone acetyltransferase activity nucleus cytoplasm skeletal muscle tissue development methyltransferase activity mRNA methyltransferase activity mRNA methyltransferase activity histone acetylation transferase activity methylation fat cell differentiation tRNA (cytosine-3-)-methyltransferase activity mRNA methylation mRNA methylation |
|
| TC0X00001322.mm.2 |
Tceal9 |
transcription elongation factor A like 9 |
X |
136245079 |
NM_011712, BC007478 NM_011712, BC007478 |
22381 |
19 |
nucleus WW domain binding WW domain binding |
|
| TC0800002878.mm.2 |
Nob1 |
NIN1/RPN12 binding protein 1 homolog |
8 |
-107412488 |
NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 |
67619 |
23 |
cleavage involved in rRNA processing nuclease activity endonuclease activity endoribonuclease activity endoribonuclease activity nucleus nucleolus cytoplasm visual perception hydrolase activity maturation of SSU-rRNA maturation of SSU-rRNA preribosome, small subunit precursor ribosomal small subunit biogenesis metal ion binding |
03008 |
| TC1700000990.mm.2 |
Adgre4 |
adhesion G protein-coupled receptor E4 |
17 |
55749983 |
NM_139138, BC120538, BC120540 NM_139138, BC120538, BC120540 NM_139138, BC120538, BC120540 |
52614 |
19 |
transmembrane signaling receptor activity G protein-coupled receptor activity calcium ion binding plasma membrane integral component of plasma membrane integral component of plasma membrane signal transduction cell surface receptor signaling pathway epidermal growth factor receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway cell surface membrane integral component of membrane |
|
| TC0100003500.mm.2 |
Nuf2 |
NUF2, NDC80 kinetochore complex component |
1 |
-169497933 |
NM_023284, BC020026 NM_023284, BC020026 |
66977 |
22 |
chromosome, centromeric region kinetochore condensed nuclear chromosome kinetochore nucleus nucleoplasm chromosome cytosol cell cycle mitotic spindle organization attachment of spindle microtubules to kinetochore Ndc80 complex Ndc80 complex protein-containing complex binding meiotic chromosome segregation cell division attachment of mitotic spindle microtubules to kinetochore kinetochore organization |
|
| TC0800002927.mm.2 |
Sf3b3 |
splicing factor 3b, subunit 3 |
8 |
-110810491 |
NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 |
101943 |
28 |
mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding nucleus nucleus nucleoplasm spliceosomal complex U2 snRNP U12-type spliceosomal complex nucleolus mRNA processing RNA splicing U2 snRNA binding negative regulation of protein catabolic process protein-containing complex binding U2-type precatalytic spliceosome catalytic step 2 spliceosome |
03040 |
| TC1700001938.mm.2 |
D17H6S56E-5 |
DNA segment, Chr 17, human D6S56E 5 |
17 |
-34996723 |
BC027314 |
110956 |
28 |
|
|
| TC0800001095.mm.2 |
Mt1 |
metallothionein 1 |
8 |
94179088 |
NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990 |
17748 |
335 |
copper ion binding nucleus cytoplasm lysosome cytosol cytosol cellular metal ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding detoxification of copper ion detoxification of copper ion negative regulation of neuron apoptotic process metal ion binding metal ion binding cellular response to chromate cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion cellular response to zinc ion |
|
| TC1300001574.mm.2 |
H2ac12 |
H2A clustered histone 12 |
13 |
-22035121 |
NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008 |
319168 |
11 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC0700003592.mm.2 |
Man2a2 |
mannosidase 2, alpha 2 |
7 |
-80349096 |
NM_172903, BC055006 NM_172903, BC055006 |
140481 |
23 |
Golgi membrane catalytic activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing protein deglycosylation metabolic process mannosidase activity membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding |
00510 01100 |
| TC0400002007.mm.2 |
Dnajc11 |
DnaJ heat shock protein family (Hsp40) member C11 |
4 |
151933719 |
NM_172704, BC085257 NM_172704, BC085257 |
230935 |
32 |
SAM complex nucleoplasm mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane membrane nuclear speck cristae formation cristae formation cristae formation MICOS complex MICOS complex |
|
| TC1900000543.mm.2 |
Cep55 |
centrosomal protein 55 |
19 |
38054983, 38054983, 38055040 |
NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 |
74107 |
31 |
mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm centrosome cytoskeleton plasma membrane cell cycle regulation of phosphatidylinositol 3-kinase signaling midbody midbody midbody centriolar satellite identical protein binding intercellular bridge establishment of protein localization establishment of protein localization cell division midbody abscission Flemming body cranial skeletal system development |
|
| TC0400001465.mm.2 |
Clspn |
claspin |
4 |
126556979 |
NM_175554, BC050848 NM_175554, BC050848 |
269582 |
26 |
DNA replication checkpoint DNA damage checkpoint DNA secondary structure binding DNA binding nucleus nucleoplasm chromosome Golgi apparatus DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint anaphase-promoting complex binding anaphase-promoting complex binding peptidyl-serine phosphorylation activation of protein kinase activity activation of protein kinase activity mitotic DNA replication checkpoint mitotic DNA replication checkpoint |
|
| TC0900001987.mm.2 |
Fli1 |
Friend leukemia integration 1 |
9 |
-32422203 |
NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792 |
14247 |
133 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleus nucleus nucleoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II blood circulation animal organ morphogenesis cellular process nuclear body cell differentiation megakaryocyte development sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC1300002543.mm.2 |
Ccnb1 |
cyclin B1 |
13 |
-100778738 |
NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 |
268697 |
210 |
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex spindle pole condensed nuclear chromosome outer kinetochore oocyte maturation in utero embryonic development negative regulation of protein phosphorylation patched binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm mitochondrial matrix mitochondrial matrix mitochondrial matrix centrosome centrosome cytosol cytoskeleton protein phosphorylation cell cycle mitotic spindle organization mitotic metaphase plate congression mitotic metaphase plate congression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding positive regulation of mRNA 3'-end processing positive regulation of histone phosphorylation ubiquitin-like protein ligase binding mitotic cell cycle phase transition protein-containing complex binding positive regulation of cell cycle positive regulation of mitotic cell cycle positive regulation of fibroblast proliferation cell division positive regulation of attachment of spindle microtubules to kinetochore positive regulation of cardiac muscle cell proliferation regulation of chromosome condensation cyclin-dependent protein serine/threonine kinase activator activity protein-containing complex assembly regulation of mitotic cell cycle spindle assembly checkpoint cyclin B1-CDK1 complex cyclin B1-CDK1 complex positive regulation of mitochondrial ATP synthesis coupled electron transport histone H3-S10 phosphorylation involved in chromosome condensation |
04110 04114 04115 04914 |
| TC1100003817.mm.2 |
Dusp3 |
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) |
11 |
-101971143 |
NM_028207, BC016269 NM_028207, BC016269 |
72349 |
39 |
inactivation of MAPK activity in utero embryonic development immunological synapse phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm cytosol cytosol protein dephosphorylation cytoskeletal protein binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/serine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity protein kinase binding negative regulation of cell migration receptor tyrosine kinase binding MAP kinase phosphatase activity MAP kinase phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation negative regulation of epidermal growth factor receptor signaling pathway negative regulation of MAPK cascade positive regulation of mitotic cell cycle positive regulation of mitotic cell cycle negative regulation of JNK cascade negative regulation of JNK cascade negative regulation of T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway negative regulation of T cell activation negative regulation of T cell activation negative regulation of chemotaxis regulation of focal adhesion assembly regulation of focal adhesion assembly negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus cellular response to epidermal growth factor stimulus positive regulation of focal adhesion disassembly peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity protein tyrosine kinase binding |
04010 |
| TC0900002036.mm.2 |
Chek1 |
checkpoint kinase 1 |
9 |
-36708481 |
NM_007691, BC100386 NM_007691, BC100386 |
12649 |
117 |
DNA damage checkpoint DNA damage checkpoint DNA damage checkpoint G2/M transition of mitotic cell cycle nucleotide binding chromosome, telomeric region chromatin condensed nuclear chromosome inner cell mass cell proliferation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome cytoplasm cytoplasm centrosome cytoskeleton DNA repair DNA repair protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus DNA damage induced protein phosphorylation nucleus organization cell cycle mitotic cell cycle checkpoint regulation of gene expression regulation of double-strand break repair via homologous recombination regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage negative regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-threonine phosphorylation protein domain specific binding protein-containing complex histone kinase activity (H3-T11 specific) histone kinase activity (H3-T11 specific) intracellular signal transduction regulation of cell population proliferation intracellular membrane-bounded organelle mitotic G2/M transition checkpoint positive regulation of cell cycle negative regulation of mitotic nuclear division regulation of mitotic centrosome separation chromatin-mediated maintenance of transcription signal transduction involved in G2 DNA damage checkpoint apoptotic process involved in development negative regulation of DNA biosynthetic process regulation of histone H3-K9 acetylation |
04110 04115 |
| TC1400000777.mm.2 |
Dhrs4 |
dehydrogenase/reductase (SDR family) member 4 |
14 |
55478757, 55478757 |
NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361 NM_001037938, NM_030686, BC003484, BC054361 |
28200 |
24 |
3-keto sterol reductase activity retinal dehydrogenase activity carbonyl reductase (NADPH) activity nucleus mitochondrion peroxisome peroxisome peroxisomal membrane alcohol metabolic process steroid metabolic process oxidoreductase activity oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor alcohol dehydrogenase [NAD(P)+] activity cellular ketone metabolic process retinal metabolic process identical protein binding |
00830 01100 04146 |
| TC0700003581.mm.2 |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
7 |
-80094846 |
NM_173011, BC060030 NM_173011, BC060030 |
269951 |
84 |
magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane peroxisome cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process NADP metabolic process NADP biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding NAD binding negative regulation of glial cell proliferation negative regulation of glial cell migration negative regulation of matrix metallopeptidase secretion |
00020 00480 01100 04146 |
| TC1300002463.mm.2 |
Iqgap2 |
IQ motif containing GTPase activating protein 2 |
13 |
-95627176 |
NM_027711, BC150958 NM_027711, BC150958 |
544963 |
39 |
GTPase activator activity calmodulin binding calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytoplasm microtubule microvillus signal transduction cell surface lamellipodium filopodium small GTPase binding regulation of actin cytoskeleton organization Arp2/3 complex-mediated actin nucleation regulation of GTPase activity actin filament binding actin filament binding thrombin-activated receptor signaling pathway Arp2/3 complex binding regulation of actin cytoskeleton reorganization |
04810 |
| TC1400001671.mm.2 |
Stab1 |
stabilin 1 |
14 |
-31139016 |
NM_138672 |
192187 |
42 |
low-density lipoprotein particle receptor activity scavenger receptor activity calcium ion binding hyaluronic acid binding cytoplasm integral component of plasma membrane inflammatory response cell adhesion cell-cell signaling membrane integral component of membrane negative regulation of angiogenesis low-density lipoprotein particle binding defense response to bacterium |
|
| TC0600001398.mm.2 |
Clec4a3 |
C-type lectin domain family 4, member a3 |
6 |
122952514, 122952643 |
NM_001204241, NM_153197, BC034893 NM_001204241, NM_153197, BC034893 NM_001204241, NM_153197, BC034893 |
73149 |
11 |
molecular_function cellular_component biological_process |
|
| TC0900002451.mm.2 |
Kif23 |
kinesin family member 23 |
9 |
-61917277 |
NM_024245, BC047273 NM_024245, BC047273 |
71819 |
34 |
nucleotide binding mitotic cytokinesis actomyosin contractile ring assembly microtubule motor activity ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle microtubule binding microtubule binding ATPase activity midbody positive regulation of cytokinesis intercellular bridge mitotic spindle midzone assembly mitotic spindle midzone assembly cell division plus-end-directed vesicle transport along microtubule mitotic spindle Flemming body centralspindlin complex |
|
| TC0100002772.mm.2 |
|
|
|
|
NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 |
|
|
chromosome, centromeric region chromosome, centromeric region condensed chromosome kinetochore DNA binding nucleus nucleoplasm chromosome nucleolus mitochondrion cell cycle chromosome segregation CENP-A containing nucleosome assembly histone binding identical protein binding regulation of protein-containing complex assembly regulation of DNA binding |
|
| TC1000001546.mm.2 |
Cdk4 |
cyclin-dependent kinase 4 |
10 |
127063534 |
NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694 |
12567 |
327 |
G1/S transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex chromatin protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex nucleolus cytoplasm cytosol bicellular tight junction protein phosphorylation protein phosphorylation protein phosphorylation cell cycle signal transduction positive regulation of cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity response to organic substance response to lead ion regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane kinase activity phosphorylation mediator complex transferase activity cyclin binding cyclin binding nuclear membrane cellular response to insulin stimulus protein-containing complex response to testosterone regulation of multicellular organism growth regulation of cell population proliferation positive regulation of apoptotic process protein-containing complex binding positive regulation of translation positive regulation of cell size regulation of insulin receptor signaling pathway regulation of lipid biosynthetic process positive regulation of fibroblast proliferation perinuclear region of cytoplasm regulation of lipid catabolic process cell division regulation of cell cycle regulation of cell cycle adipose tissue development negative regulation of cell cycle arrest cellular response to lipopolysaccharide cellular response to interleukin-4 cyclin D2-CDK4 complex cellular response to phorbol 13-acetate 12-myristate cellular response to ionomycin |
04110 04115 04530 04660 05200 05212 05214 05218 05219 05220 05222 05223 |
| TC1400001665.mm.2 |
|
|
|
|
NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 |
|
|
nucleotide binding molecular_function protein binding GTP binding GTP binding cellular_component nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus biological_process cell population proliferation nuclear body stem cell division stem cell population maintenance midbody positive regulation of telomere maintenance positive regulation of protein sumoylation regulation of cell population proliferation mRNA 5'-UTR binding positive regulation of pri-miRNA transcription by RNA polymerase II positive regulation of protein localization to chromosome, telomeric region |
|
| TC0600003268.mm.2 |
Ybx3 |
Y box protein 3 |
6 |
-131364857 |
NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 |
56449 |
53 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development nucleic acid binding DNA binding single-stranded DNA binding single-stranded DNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm cytosol gap junction spermatogenesis male gonad development fertilization regulation of gene expression ribonucleoprotein complex binding negative regulation of apoptotic process positive regulation of organ growth negative regulation of skeletal muscle tissue development negative regulation of necroptotic process cellular response to tumor necrosis factor cellular hyperosmotic response negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress polysome binding |
04530 |
| TC0300002797.mm.2 |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
3 |
-115710432 |
NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023 |
13609 |
252 |
angiogenesis angiogenesis G protein-coupled receptor binding blood vessel maturation cardiac muscle tissue growth involved in heart morphogenesis sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway G protein-coupled receptor activity G protein-coupled receptor activity nucleoplasm cytoplasm endosome plasma membrane chemotaxis signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway brain development positive regulation of cell population proliferation external side of plasma membrane membrane integral component of membrane cell migration regulation of metabolic process lamellipodium assembly regulation of cell adhesion positive regulation of cell migration regulation of bone mineralization leukocyte chemotaxis intrinsic component of plasma membrane actin cytoskeleton reorganization sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity intracellular membrane-bounded organelle positive regulation of GTPase activity regulation of bone resorption positive regulation of transcription by RNA polymerase II sphingolipid binding positive regulation of smooth muscle cell proliferation positive regulation of positive chemotaxis positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway negative regulation of stress fiber assembly heart trabecula morphogenesis T cell migration |
04080 |
| TC1100003399.mm.2 |
Ccl6 |
chemokine (C-C motif) ligand 6 |
11 |
-83587885 |
NM_009139, BC002073 NM_009139, BC002073 |
20305 |
34 |
monocyte chemotaxis cytokine activity extracellular region extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity chemokine activity neutrophil chemotaxis positive regulation of GTPase activity CCR chemokine receptor binding lymphocyte chemotaxis cell chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor |
04060 04062 |
| TC0900001792.mm.2 |
Fat3 |
FAT atypical cadherin 3 |
9 |
-15910189 |
NM_001080814 |
270120 |
25 |
cell morphogenesis involved in differentiation neuron migration calcium ion binding plasma membrane cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules multicellular organism development retina layer formation membrane integral component of membrane dendrite cell-cell adhesion negative regulation of dendrite development |
|
| TC0500003169.mm.2 |
Tpcn1 |
two pore channel 1 |
5 |
-120534156 |
NM_145853, BC058951 NM_145853, BC058951 |
252972 |
40 |
ion channel activity voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated sodium channel activity calcium channel activity lysosome lysosomal membrane lysosomal membrane endosome ion transport calcium ion transport endosome membrane endosome membrane positive regulation of autophagy ligand-gated sodium channel activity membrane integral component of membrane regulation of ion transmembrane transport sodium ion transmembrane transport identical protein binding protein homodimerization activity transmembrane transport calcium ion transmembrane transport NAADP-sensitive calcium-release channel activity NAADP-sensitive calcium-release channel activity phosphatidylinositol-3,5-bisphosphate binding |
|
| TC0900002044.mm.2 |
Slc37a2 |
solute carrier family 37 (glycerol-3-phosphate transporter), member 2 |
9 |
-37229148 |
NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326 |
56857 |
18 |
endoplasmic reticulum glycerol-3-phosphate metabolic process glycerophosphate shuttle carbohydrate transport glycerol-3-phosphate transmembrane transporter activity antiporter activity glucose-6-phosphate transport glucose-6-phosphate transport glycerol-3-phosphate transmembrane transport membrane integral component of membrane transmembrane transporter activity integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane phosphate ion transmembrane transport phosphate ion transmembrane transport transmembrane transport glucose 6-phosphate:inorganic phosphate antiporter activity glucose 6-phosphate:inorganic phosphate antiporter activity |
|
| TC0100001058.mm.2 |
Nifk |
nucleolar protein interacting with the FHA domain of MKI67 |
1 |
118321842 |
NM_026472, BC058559 NM_026472, BC058559 |
67949 |
21 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed nuclear chromosome nucleic acid binding RNA binding RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm |
|
| TC0700000896.mm.2 |
Nav2 |
neuron navigator 2 |
7 |
49246188, 48959072 |
NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 |
78286 |
34 |
regulation of systemic arterial blood pressure by baroreceptor feedback interstitial matrix nucleoplasm nervous system development nervous system development sensory perception of sound sensory perception of smell locomotory behavior heparin binding optic nerve development glossopharyngeal nerve development vagus nerve development cerebellar cortex development extracellular matrix 3'-5' DNA helicase activity |
|
| TC0300002955.mm.2 |
Hadh |
hydroxyacyl-Coenzyme A dehydrogenase |
3 |
-131233419 |
NM_008212, BC064712 NM_008212, BC064712 |
15107 |
40 |
3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity protein binding nucleoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation response to activity oxidoreductase activity response to drug identical protein binding negative regulation of insulin secretion regulation of insulin secretion NAD+ binding positive regulation of cold-induced thermogenesis |
00062 00071 00280 00310 00380 00650 01100 |
| TC0500002231.mm.2 |
Mxd4 |
Max dimerization protein 4 |
5 |
-34176579 |
NM_010753, BC011303 NM_010753, BC011303 |
17122 |
31 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding protein binding nucleus regulation of transcription by RNA polymerase II negative regulation of transcription, DNA-templated protein dimerization activity RNA polymerase II transcription regulator complex |
|
| TC0300001757.mm.2 |
Ect2 |
ect2 oncogene |
3 |
-27097221, -27097221 |
NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 |
13605 |
48 |
mitotic cytokinesis mitotic cytokinesis cell morphogenesis guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytoskeleton cell-cell junction bicellular tight junction cell cortex cell cycle nervous system development protein transport nuclear body cell junction cell differentiation midbody small GTPase binding activation of protein kinase activity cleavage furrow positive regulation of cytokinesis regulation of Rho protein signal transduction intracellular signal transduction positive regulation of protein import into nucleus protein homodimerization activity positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of neuron differentiation regulation of protein kinase activity protein homooligomerization cell division regulation of attachment of spindle microtubules to kinetochore cellular response to hydrogen peroxide bicellular tight junction assembly cellular response to calcium ion cellular response to ionizing radiation mitotic spindle activation of GTPase activity activation of GTPase activity centralspindlin complex regulation of cytokinesis, actomyosin contractile ring assembly |
|
| TC1000001579.mm.2 |
Prim1 |
DNA primase, p49 subunit |
10 |
128015214 |
NM_008921, BC089544 NM_008921, BC089544 |
19075 |
29 |
DNA primase activity DNA primase activity DNA-directed 5'-3' RNA polymerase activity protein binding alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer transferase activity nucleotidyltransferase activity metal ion binding primosome complex |
00230 00240 01100 03030 |
| TC1100004157.mm.2 |
Timp2 |
tissue inhibitor of metalloproteinase 2 |
11 |
-118301060 |
NM_011594, BC049126 NM_011594, BC049126 |
21858 |
152 |
protease binding protease binding enzyme inhibitor activity integrin binding integrin binding extracellular region basement membrane extracellular space extracellular space extracellular space enzyme activator activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation response to hormone cell surface cell surface response to organic substance negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity growth cone extracellular matrix regulation of Rap protein signal transduction response to cytokine neuron projection neuronal cell body regulation of MAPK cascade positive regulation of MAPK cascade regulation of neuron differentiation regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of adenylate cyclase activity negative regulation of proteolysis negative regulation of mitotic cell cycle negative regulation of Ras protein signal transduction metal ion binding negative regulation of membrane protein ectodomain proteolysis cellular response to organic substance negative regulation of metallopeptidase activity |
|
| TC0200003109.mm.2 |
Hnmt |
histamine N-methyltransferase |
2 |
-24002912 |
NM_080462, BC033928 NM_080462, BC033928 |
140483 |
21 |
regulation of neurotransmitter levels histamine metabolic process histamine catabolic process nucleoplasm cytoplasm centrosome cytosol methyltransferase activity N-methyltransferase activity transferase activity methylation neuron projection histamine N-methyltransferase activity |
00340 |
| TC0500003516.mm.2 |
Gna12 |
guanine nucleotide binding protein, alpha 12 |
5 |
-140759943 |
NM_010302, BC111810 NM_010302, BC111810 |
14673 |
87 |
nucleotide binding G protein-coupled receptor binding in utero embryonic development GTPase activity GTPase activity GTPase activity GTP binding cytoplasm heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway Rho protein signal transduction Rho protein signal transduction regulation of cell shape regulation of fibroblast migration membrane guanyl nucleotide binding cell differentiation brush border membrane brush border membrane G-protein beta/gamma-subunit complex binding D5 dopamine receptor binding D5 dopamine receptor binding regulation of TOR signaling regulation of TOR signaling regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of proteasomal ubiquitin-dependent protein catabolic process intracellular signal transduction embryonic digit morphogenesis metal ion binding negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration |
04010 04270 04730 04810 |
| TC0600000772.mm.2 |
Mad2l1 |
MAD2 mitotic arrest deficient-like 1 |
6 |
66535220 |
NM_019499, BC089012 NM_019499, BC089012 |
56150 |
81 |
mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore kinetochore spindle pole protein binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytoplasm cytosol cytoskeleton cell cycle mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint protein C-terminus binding negative regulation of protein catabolic process identical protein binding protein homodimerization activity negative regulation of apoptotic process negative regulation of apoptotic process nuclear pore nuclear basket negative regulation of mitotic metaphase/anaphase transition negative regulation of mitotic cell cycle perinuclear region of cytoplasm cell division establishment of centrosome localization mitotic spindle positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic cell cycle spindle assembly checkpoint negative regulation of ubiquitin protein ligase activity |
04110 04114 04914 |
| TC0200004207.mm.2 |
Ldlrad3 |
low density lipoprotein receptor class A domain containing 3 |
2 |
-101950200 |
NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 |
241576 |
17 |
amyloid-beta binding plasma membrane receptor-mediated endocytosis membrane integral component of membrane regulation of protein processing |
|
| TC0200001906.mm.2 |
Blvra |
biliverdin reductase A |
2 |
127070656 |
NM_026678, BC052146 NM_026678, BC052146 |
109778 |
37 |
nucleotide binding biliverdin reductase (NAD(P)+) activity biliverdin reductase (NAD(P)+) activity biliverdin reductase (NAD(P)+) activity cytoplasm cytosol zinc ion binding oxidoreductase activity heme catabolic process metal ion binding |
00860 |
| TC0100003679.mm.2 |
Ephx1 |
epoxide hydrolase 1, microsomal |
1 |
-180989555 |
NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 NM_010145, BC029636, BC045194, BC057857, BC061493 |
13849 |
51 |
catalytic activity epoxide hydrolase activity endoplasmic reticulum plasma membrane cellular aromatic compound metabolic process response to toxic substance response to organic cyclic compound membrane integral component of membrane hydrolase activity arachidonic acid metabolic process aromatic compound catabolic process enzyme binding cis-stilbene-oxide hydrolase activity diol biosynthetic process intracellular membrane-bounded organelle epoxide metabolic process |
00980 04976 |
| TC0600001448.mm.2 |
Nop2 |
NOP2 nucleolar protein |
6 |
125131882 |
NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151 |
110109 |
37 |
ribosomal large subunit assembly maturation of LSU-rRNA RNA methylation blastocyst formation RNA binding nucleus nucleolus nucleolus rRNA processing methyltransferase activity positive regulation of cell population proliferation S-adenosylmethionine-dependent methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity transferase activity methylation ribosome biogenesis rRNA base methylation regulation of signal transduction by p53 class mediator |
|
| TC0300000693.mm.2 |
Cd5l |
CD5 antigen-like |
3 |
87357880 |
NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like NM_009690, BC006799, BC094459, CD5-like |
11801 |
46 |
immune system process serine-type endopeptidase activity scavenger receptor activity extracellular region cytoplasm plasma membrane plasma membrane apoptotic process inflammatory response cell surface cell surface membrane regulation of complement activation zymogen activation positive regulation of complement-dependent cytotoxicity |
|
| TC0600001508.mm.2 |
|
|
|
|
NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 |
|
|
G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding vasculogenesis liver development molecular_function DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding cellular_component nucleus nucleus DNA repair regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle biological_process positive regulation of cell population proliferation positive regulation of cell population proliferation protein kinase binding negative regulation of stress-activated MAPK cascade regulation of cell population proliferation regulation of cell population proliferation sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of Ras protein signal transduction regulation of cell cycle arrest regulation of cell cycle arrest negative regulation of cell aging regulation of reactive oxygen species metabolic process positive regulation of double-strand break repair positive regulation of double-strand break repair |
|
| TC1200001030.mm.2 |
Ifi27 |
interferon, alpha-inducible protein 27 |
12 |
103434188 |
NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 |
52668 |
21 |
negative regulation of transcription by RNA polymerase II RNA polymerase II activating transcription factor binding lamin binding nuclear inner membrane mitochondrion regulation of protein export from nucleus apoptotic signaling pathway |
|
| TC0600001033.mm.2 |
Ruvbl1 |
RuvB-like protein 1 |
6 |
88465408 |
NM_019685, BC004718 NM_019685, BC004718 |
56505 |
53 |
nucleotide binding box C/D snoRNP assembly Swr1 complex Swr1 complex TFIID-class transcription factor complex binding DNA helicase activity DNA helicase activity transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm cytosol DNA repair DNA recombination chromatin organization chromatin remodeling regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus cell cycle positive regulation of plasminogen activation nuclear matrix histone acetylation hydrolase activity ATPase activity TBP-class protein binding Ino80 complex Ino80 complex protein-containing complex NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth 3'-5' DNA helicase activity 5'-3' DNA helicase activity ADP binding histone H4 acetylation histone H2A acetylation ATPase binding cell division MLL1 complex positive regulation of canonical Wnt signaling pathway R2TP complex R2TP complex ribonucleoprotein complex regulation of fibroblast apoptotic process |
04310 |
| TC1100003059.mm.2 |
|
|
|
|
NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 NM_001034097, NM_001159503, NM_001159505, NM_011614, NM_023517, BC069900, BC096441 |
|
|
angiogenesis immune system process immunoglobulin production in mucosal tissue positive regulation of germinal center formation cytokine activity tumor necrosis factor receptor binding extracellular region extracellular region extracellular space cytoplasm plasma membrane apoptotic process immune response multicellular organism development positive regulation of cell population proliferation external side of plasma membrane membrane integral component of membrane immunoglobulin mediated immune response cell differentiation positive regulation of protein catabolic process receptor ligand activity positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgA isotypes perinuclear region of cytoplasm regulation of immune response extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway |
|
| TC1300002654.mm.2 |
Gapt |
Grb2-binding adaptor, transmembrane |
13 |
-110352614 |
NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005 |
238875 |
14 |
B cell homeostasis B cell homeostasis B cell proliferation involved in immune response B cell proliferation involved in immune response immunoglobulin production involved in immunoglobulin-mediated immune response immunoglobulin production involved in immunoglobulin-mediated immune response Golgi apparatus plasma membrane membrane integral component of membrane B cell activation intracellular membrane-bounded organelle |
|
| TC1600001320.mm.2 |
Cdc45 |
cell division cycle 45 |
16 |
-18780446 |
NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635 |
12544 |
41 |
double-strand break repair via break-induced replication chromatin binding DNA replication origin binding single-stranded DNA binding nucleus nucleoplasm centrosome DNA replication DNA replication initiation cell cycle DNA replication preinitiation complex regulation of chromatin silencing at telomere ciliary basal body mitotic DNA replication preinitiation complex assembly |
04110 |
| TC0200001056.mm.2 |
Cdca7 |
cell division cycle associated 7 |
2 |
72476218 |
NM_025866, BC066169 NM_025866, BC066169 |
66953 |
36 |
molecular_function nucleus nucleus nucleoplasm cytoplasm cytosol regulation of transcription, DNA-templated apoptotic process regulation of cell population proliferation |
|
| TC1100002694.mm.2 |
Hnrnpab |
heterogeneous nuclear ribonucleoprotein A/B |
11 |
-51600099 |
NM_001048061, NM_010448, BC043069 NM_001048061, NM_010448, BC043069 NM_001048061, NM_010448, BC043069 |
15384 |
55 |
negative regulation of transcription by RNA polymerase II epithelial to mesenchymal transition nucleic acid binding DNA binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm regulation of gene expression positive regulation of transcription, DNA-templated RNA polymerase II transcription regulator complex presynaptic cytosol ribonucleoprotein complex |
|
| TC0100003505.mm.2 |
Hsd17b7 |
hydroxysteroid (17-beta) dehydrogenase 7 |
1 |
-169949536 |
NM_010476 |
15490 |
38 |
3-keto sterol reductase activity 3-keto sterol reductase activity 3-keto sterol reductase activity estradiol 17-beta-dehydrogenase activity estradiol 17-beta-dehydrogenase activity prolactin receptor binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process estrogen biosynthetic process estrogen biosynthetic process nervous system development brain development androgen metabolic process androgen metabolic process membrane integral component of membrane oxidoreductase activity cell differentiation 5alpha-androstane-3beta,17beta-diol dehydrogenase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity embryonic organ development embryonic skeletal system development |
00100 00140 01100 |
| TC1000000402.mm.2 |
Cd24a |
CD24a antigen |
10 |
43579168 |
NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a |
12484 |
167 |
response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation immune system process leukocyte migration involved in inflammatory response positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptotic process protein binding plasma membrane plasma membrane cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion cell surface receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuromuscular synaptic transmission neuromuscular synaptic transmission negative regulation of neuroblast proliferation apoptotic mitochondrial changes external side of plasma membrane external side of plasma membrane cell surface positive regulation of neuron projection development positive regulation of neuron projection development membrane membrane cell migration protein kinase binding regulation of cell-cell adhesion positive regulation of cell-cell adhesion carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity Hsp70 protein binding negative regulation of B cell proliferation neuron projection development neuron projection development anchored component of membrane T cell costimulation anchored component of external side of plasma membrane anchored component of external side of plasma membrane anchored component of external side of plasma membrane microvillus membrane chemokine receptor transport out of membrane raft negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of transforming growth factor beta3 production positive regulation of integrin activation positive regulation of integrin activation positive regulation of cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin regulation of cell-cell adhesion mediated by integrin positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPK cascade response to estrogen innate immune response membrane raft membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of neurogenesis positive regulation of calcium-mediated signaling Hsp90 protein binding ciliary membrane negative regulation of monocyte chemotactic protein-1 production apoptotic signaling pathway negative regulation of inflammatory response to wounding positive regulation of inflammatory response to wounding |
04640 |
| TC1100001634.mm.2 |
Atp6v0a1 |
ATPase, H+ transporting, lysosomal V0 subunit A1 |
11 |
101010397, 101009440, 101009440, 101009440 |
NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 |
11975 |
48 |
vacuolar proton-transporting V-type ATPase, V0 domain protein binding cytoplasm Golgi apparatus cytosol plasma membrane plasma membrane ion transport vacuolar acidification synaptic vesicle proton transmembrane transporter activity membrane integral component of membrane regulation of macroautophagy vacuolar proton-transporting V-type ATPase complex nuclear speck integral component of synaptic vesicle membrane cytoplasmic vesicle proton-transporting V-type ATPase, V0 domain intracellular organelle intracellular membrane-bounded organelle proton-transporting ATPase activity, rotational mechanism perinuclear region of cytoplasm ATPase binding ATPase binding toxin transport proton transmembrane transport |
00190 01100 04142 04145 04966 05323 |
| TC1100003434.mm.2 |
Brip1 |
BRCA1 interacting protein C-terminal helicase 1 |
11 |
-86058135 |
NM_178309, BC094252 NM_178309, BC094252 |
237911 |
22 |
nucleotide binding nucleic acid binding DNA binding DNA helicase activity chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm cytoplasm nucleobase-containing compound metabolic process DNA repair nucleotide-excision repair regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus homologous chromosome pairing at meiosis spermatogenesis spermatogonial cell division spermatid development negative regulation of cell population proliferation male gonad development negative regulation of gene expression meiotic DNA double-strand break processing involved in reciprocal meiotic recombination hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides nuclear membrane metal ion binding chiasma assembly iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding seminiferous tubule development double-strand break repair involved in meiotic recombination double-strand break repair involved in meiotic recombination |
|
| TC0100001381.mm.2 |
Rgs16 |
regulator of G-protein signaling 16 |
1 |
153740352 |
NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459 NM_011267, BC010980, BC049968, BC055459 |
19734 |
45 |
GTPase activator activity GTPase activator activity GTPase activator activity protein binding cytoplasm cytoplasm G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway negative regulation of signal transduction membrane intrinsic component of membrane positive regulation of GTPase activity positive regulation of GTPase activity membrane raft |
|
| TC1200001460.mm.2 |
Lpin1 |
lipin 1 |
12 |
-16535668, -16535668 |
NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 |
14245 |
127 |
negative regulation of transcription by RNA polymerase II mitochondrial fission RNA polymerase II transcription factor binding transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus transcription regulator complex cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum DNA replication regulation of transcription by RNA polymerase II lipid metabolic process triglyceride mobilization immune response phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity fatty acid catabolic process fatty acid catabolic process membrane hydrolase activity triglyceride biosynthetic process positive regulation of histone deacetylation ruffle organization actin cytoskeleton reorganization negative regulation of myelination nuclear membrane cellular response to insulin stimulus cellular response to insulin stimulus cellular response to insulin stimulus histone deacetylase binding peroxisome proliferator activated receptor binding cellular lipid metabolic process cellular lipid metabolic process fat cell differentiation regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II phosphatidic acid metabolic process positive regulation of cold-induced thermogenesis regulation of phosphatidate phosphatase activity |
|
| TC0500000008.mm.2 |
Cdk6 |
cyclin-dependent kinase 6 |
5 |
3343892 |
NM_009873, BC119360, BC120595 NM_009873, BC119360, BC120595 NM_009873, BC119360, BC120595 |
12571 |
139 |
negative regulation of transcription by RNA polymerase II nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion hematopoietic progenitor cell differentiation type B pancreatic cell development protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome cytosol cytoskeleton protein phosphorylation protein phosphorylation cell cycle Notch signaling pathway Notch signaling pathway RNA polymerase II CTD heptapeptide repeat kinase activity regulation of gene expression positive regulation of gene expression kinase activity phosphorylation mediator complex transferase activity hemopoiesis cell differentiation cyclin binding T cell differentiation in thymus response to 5-fluorouracil gliogenesis regulation of cell population proliferation cell projection cell dedifferentiation cell quiescence negative regulation of myeloid cell differentiation regulation of erythrocyte differentiation negative regulation of monocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division regulation of cell cycle hematopoietic stem cell differentiation cyclin D2-CDK6 complex FBXO family protein binding regulation of hematopoietic stem cell differentiation negative regulation of cellular senescence |
04110 04115 05200 05212 05214 05218 05220 05222 05223 |
| TC1400001031.mm.2 |
Rcbtb2 |
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
14 |
73142509, 73142784 |
NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 |
105670 |
17 |
acrosomal vesicle molecular_function biological_process cytoplasmic vesicle |
|
| TC1200000596.mm.2 |
Frmd6 |
FERM domain containing 6 |
12 |
70825513 |
NM_028127, BC053929 NM_028127, BC053929 |
319710 |
24 |
apical constriction protein binding cytoplasm cytoskeleton plasma membrane membrane actomyosin structure organization regulation of actin filament-based process cellular protein localization apical junction complex |
|
| TC0400001158.mm.2 |
Kti12 |
KTI12 homolog, chromatin associated |
4 |
108847856 |
NM_029571, BC021493 NM_029571, BC021493 |
100087 |
12 |
nucleotide binding tRNA wobble uridine modification molecular_function ATP binding regulation of transcription by RNA polymerase II elongator holoenzyme complex |
|
| TC1300000260.mm.2 |
H2ac4 |
H2A clustered histone 4 |
13 |
23751087 |
NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047 |
319172 |
7 |
DNA binding nucleus chromatin silencing |
05322 |
| TC1000000422.mm.2 |
Prep |
prolyl endopeptidase |
10 |
45067215 |
NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830 |
19072 |
58 |
endopeptidase activity endopeptidase activity serine-type endopeptidase activity nucleus cytoplasm cytosol cytosol proteolysis peptidase activity serine-type peptidase activity hydrolase activity protein metabolic process peptide binding serine-type exopeptidase activity oligopeptidase activity |
|
| TC1400002231.mm.2 |
Msra |
methionine sulfoxide reductase A |
14 |
-64122620, -64122620, -64122620, -64122620, -64122620 |
NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 |
110265 |
79 |
nucleus nucleoplasm cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion cytosol plasma membrane aging peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity actin cytoskeleton membrane oxidoreductase activity cellular response to oxidative stress L-methionine-(S)-S-oxide reductase activity |
|
| TC0400001129.mm.2 |
Ndc1 |
NDC1 transmembrane nucleoporin |
4 |
107368046 |
NM_028355, BC021337 NM_028355, BC021337 |
72787 |
28 |
nucleus nuclear pore nuclear pore cytoplasm plasma membrane nuclear pore organization homologous chromosome pairing at meiosis spermatogenesis protein transport actin cytoskeleton membrane integral component of membrane structural constituent of nuclear pore protein-macromolecule adaptor activity nuclear membrane mRNA transport nuclear pore complex assembly nuclear pore localization nuclear pore transmembrane ring |
03013 |
| TC1400000980.mm.2 |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
14 |
69337150, 69555400 |
NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 |
67464 |
23 |
Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane |
00230 00240 04142 |
| TC1100000573.mm.2 |
Nhp2 |
NHP2 ribonucleoprotein |
11 |
51619772 |
NM_026631, BC024944 NM_026631, BC024944 |
52530 |
29 |
cleavage involved in rRNA processing maturation of LSU-rRNA RNA binding RNA binding protein binding nucleus telomerase holoenzyme complex nucleolus rRNA processing telomere maintenance via telomerase rRNA pseudouridine synthesis snRNA pseudouridine synthesis box H/ACA snoRNP complex box H/ACA snoRNP complex box H/ACA snoRNA binding box H/ACA snoRNA binding ribosome biogenesis telomerase RNA binding box H/ACA telomerase RNP complex |
03008 |
| TC0600000570.mm.2 |
Tmem176a |
transmembrane protein 176A |
6 |
48841655, 48841482 |
NM_001098271, NM_025326, BC010831 NM_001098271, NM_025326, BC010831 NM_001098271, NM_025326, BC010831 |
66058 |
18 |
protein binding membrane integral component of membrane negative regulation of dendritic cell differentiation negative regulation of dendritic cell differentiation |
|
| TC0300001488.mm.2 |
Mcoln3 |
mucolipin 3 |
3 |
146121790 |
NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857 |
171166 |
53 |
cation channel activity cytoplasm lysosomal membrane endosome plasma membrane plasma membrane ion transport sensory perception of sound locomotory behavior lipid binding membrane integral component of membrane cytoplasmic vesicle inner ear auditory receptor cell differentiation cell projection NAADP-sensitive calcium-release channel activity |
|
| TC1100004128.mm.2 |
Srsf2 |
serine and arginine-rich splicing factor 2 |
11 |
-116849896 |
NM_011358, BC005493 NM_011358, BC005493 |
20382 |
92 |
regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding protein kinase C binding protein binding nucleus nucleus nucleoplasm spliceosomal complex cytoplasm cytosol mRNA processing RNA splicing nuclear speck nuclear speck nuclear speck interchromatin granule pre-mRNA binding regulation of RNA splicing |
03040 |
| TC0600001852.mm.2 |
Ica1 |
islet cell autoantigen 1 |
6 |
-8630526, -8630526 |
NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030 |
15893 |
37 |
Golgi membrane protein binding cytoplasm Golgi apparatus Golgi stack cytosol cytosol neurotransmitter transport membrane protein domain specific binding cell junction dendrite secretory granule membrane synaptic vesicle membrane cytoplasmic vesicle intracellular membrane-bounded organelle regulation of protein-containing complex assembly synapse regulation of neurotransmitter secretion perinuclear region of cytoplasm regulation of insulin secretion regulation of transport membrane curvature sensor activity |
04940 |
| TC0200001972.mm.2 |
|
|
|
|
NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355 |
|
|
fibrillar center molecular_function RNA binding cellular_component nucleus sno(s)RNA-containing ribonucleoprotein complex cytoplasm biological_process snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis pre-snoRNP complex histone methyltransferase binding |
|
| TC1600002082.mm.2 |
Gart |
phosphoribosylglycinamide formyltransferase |
16 |
-91621396 |
NM_010256, BC070465 NM_010256, BC070465 |
14450 |
40 |
nucleotide binding catalytic activity phosphoribosylamine-glycine ligase activity phosphoribosylamine-glycine ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylglycinamide formyltransferase activity ATP binding cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glycine metabolic process metabolic process biosynthetic process purine nucleobase biosynthetic process ribonucleoside monophosphate biosynthetic process response to organic substance response to inorganic substance transferase activity hydroxymethyl-, formyl- and related transferase activity ligase activity adenine biosynthetic process tetrahydrofolate biosynthetic process metal ion binding |
00230 00670 01100 |
| TC0900001210.mm.2 |
Tfdp2 |
transcription factor Dp 2 |
9 |
96259247, 96196274, 96258704 |
NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 |
211586 |
37 |
mitotic cell cycle RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity transcription coregulator activity protein binding nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle transcription factor binding protein domain specific binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of cell cycle mitotic spindle RNA polymerase II transcription regulator complex |
04110 |
| TC1300000240.mm.2 |
|
|
|
|
NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 |
|
|
nuclear chromosome nucleosome DNA binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly chromatin silencing negative regulation of cell population proliferation enzyme binding protein-containing complex regulation of gene silencing |
|
| TC0100002481.mm.2 |
Idh1 |
isocitrate dehydrogenase 1 (NADP+), soluble |
1 |
-65158615, -65158615 |
NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986 |
15926 |
147 |
magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisome cytosol cytosol cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process isocitrate metabolic process 2-oxoglutarate metabolic process NADP metabolic process glutathione metabolic process response to oxidative stress response to organic cyclic compound oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding protein homodimerization activity metal ion binding response to steroid hormone NADP binding NAD binding regulation of phospholipid catabolic process regulation of phospholipid biosynthetic process |
00020 00480 01100 04146 |
| TC1200001348.mm.2 |
Efr3b |
EFR3 homolog B |
12 |
-3962553 |
NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968 |
668212 |
14 |
molecular_function cytoplasm cytosol plasma membrane plasma membrane actin cytoskeleton membrane phosphatidylinositol phosphorylation protein localization to plasma membrane protein localization to plasma membrane |
|
| TC0900000854.mm.2 |
Pclaf |
PCNA clamp associated factor |
9 |
65890322 |
NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393 |
68026 |
31 |
chromatin binding chromatin binding nucleus nucleus cytoplasm centrosome DNA replication DNA repair cellular response to DNA damage stimulus centrosome cycle response to UV translesion synthesis translesion synthesis perinuclear region of cytoplasm regulation of cell cycle |
|
| TC0700003024.mm.2 |
Grwd1 |
glutamate-rich WD repeat containing 1 |
7 |
-45825225, -45825222 |
NM_153419, BC028896 NM_153419, BC028896 |
101612 |
19 |
chromatin binding DNA replication origin binding nucleus nucleoplasm chromosome nucleolus cytosol DNA replication nucleosome assembly nucleosome disassembly protein-containing complex histone binding |
|
| TC0600000711.mm.2 |
Abcg2 |
ATP binding cassette subfamily G member 2 (Junior blood group) |
6 |
58596671, 58584532, 58640545, 58595959 |
NM_011920, BC053730 NM_011920, BC053730 |
26357 |
176 |
nucleotide binding ATP binding nucleus nucleoplasm mitochondrion plasma membrane plasma membrane plasma membrane cytoskeletal protein binding organic anion transmembrane transporter activity ABC-type xenobiotic transporter activity urate transmembrane transporter activity biotin transmembrane transporter activity efflux transmembrane transporter activity efflux transmembrane transporter activity organic anion transport urate transport biotin transport membrane integral component of membrane apical plasma membrane apical plasma membrane ATPase activity glucuronoside metabolic process brush border membrane riboflavin transmembrane transporter activity riboflavin transmembrane transporter activity riboflavin transport riboflavin transport ATPase-coupled transmembrane transporter activity identical protein binding protein homodimerization activity amide transmembrane transporter activity xenobiotic transmembrane transporter activity membrane raft urate metabolic process transmembrane transport embryonic process involved in female pregnancy protein-containing complex assembly transepithelial transport urate salt excretion external side of apical plasma membrane export across plasma membrane negative regulation of intestinal absorption cellular detoxification xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic transport across blood-brain barrier |
02010 04976 |
| TC1500002223.mm.2 |
Lima1 |
LIM domain and actin binding 1 |
15 |
-99778467, -99778467 |
NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490 |
65970 |
51 |
stress fiber ruffle actin binding actin monomer binding protein binding cytoplasm cytosol cytoskeleton plasma membrane plasma membrane brush border focal adhesion lipid metabolic process steroid metabolic process cholesterol metabolic process actin cytoskeleton actin cytoskeleton actin cytoskeleton membrane cell migration intestinal cholesterol absorption negative regulation of actin filament depolymerization brush border membrane ruffle organization ruffle organization cleavage furrow cholesterol homeostasis cell projection metal ion binding actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly |
|
| TC1000002493.mm.2 |
Gamt |
guanidinoacetate methyltransferase |
10 |
-80258150 |
NM_010255, BC049233 NM_010255, BC049233 |
14431 |
39 |
nucleus cytoplasm cytosol creatine biosynthetic process creatine biosynthetic process creatine biosynthetic process spermatogenesis methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity animal organ morphogenesis transferase activity guanidinoacetate N-methyltransferase activity guanidinoacetate N-methyltransferase activity methylation regulation of multicellular organism growth identical protein binding cell projection S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process |
00260 00330 01100 |
| TC1200002411.mm.2 |
Ckb |
creatine kinase, brain |
12 |
-111669354 |
NM_021273, BC015271, BC106109 NM_021273, BC015271, BC106109 NM_021273, BC015271, BC106109 |
12709 |
78 |
nucleotide binding catalytic activity creatine kinase activity creatine kinase activity protein binding ATP binding extracellular space nucleus cytoplasm mitochondrion cytosol kinase activity transferase activity transferase activity, transferring phosphorus-containing groups dendrite cellular chloride ion homeostasis ubiquitin protein ligase binding neuronal cell body myelin sheath phosphocreatine biosynthetic process |
00330 01100 |
| TC1400001174.mm.2 |
Uchl3 |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
14 |
101653966 |
NM_016723, BC048481 NM_016723, BC048481 |
50933 |
43 |
thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity intracellular anatomical structure nucleoplasm cytoplasm cytosol proteolysis ubiquitin-dependent protein catabolic process adult walking behavior peptidase activity peptidase activity cysteine-type peptidase activity protein deubiquitination protein deubiquitination protein deubiquitination protein deubiquitination hydrolase activity protein catabolic process protein catabolic process cellular response to insulin stimulus eating behavior ubiquitin binding positive regulation of fat cell differentiation retina development in camera-type eye ubiquitinyl hydrolase activity |
|
| TC0200001951.mm.2 |
Slc20a1 |
solute carrier family 20, member 1 |
2 |
129198772, 129207095, 129198772 |
NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085 |
20515 |
63 |
inorganic phosphate transmembrane transporter activity high-affinity inorganic phosphate:sodium symporter activity plasma membrane integral component of plasma membrane sodium ion transport phosphate ion transport symporter activity membrane integral component of membrane biomineral tissue development phosphate ion transmembrane transport |
|
| TC0700000798.mm.2 |
|
|
|
|
NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 |
|
|
molecular_function cellular_component biological_process |
|
| TC0300001181.mm.2 |
Dph5 |
diphthamide biosynthesis 5 |
3 |
115888182 |
NM_027193, BC060372 NM_027193, BC060372 |
69740 |
16 |
diphthine synthase activity cellular_component methyltransferase activity transferase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine methylation |
|
| TC0800002153.mm.2 |
Ankrd37 |
ankyrin repeat domain 37 |
8 |
-45996907 |
NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377 |
654824 |
14 |
protein binding nucleus nucleoplasm cytoplasm mitochondrion cytosol biological_process |
|
| TC0800001258.mm.2 |
Utp4 |
UTP4 small subunit processome component |
8 |
106893639 |
NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113 |
21771 |
28 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleus chromosome nucleolus regulation of transcription, DNA-templated rRNA processing maturation of SSU-rRNA 90S preribosome small-subunit processome t-UTP complex t-UTP complex ribosome biogenesis |
03008 |
| TC0800001493.mm.2 |
Cdt1 |
chromatin licensing and DNA replication factor 1 |
8 |
122568014 |
NM_026014, BC048076 NM_026014, BC048076 |
67177 |
45 |
DNA replication checkpoint DNA replication checkpoint DNA replication checkpoint mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore DNA binding DNA binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm chromosome DNA replication cell cycle chromosome segregation nuclear body regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation positive regulation of protein-containing complex assembly regulation of chromosome organization regulation of nuclear cell cycle DNA replication positive regulation of chromatin binding positive regulation of DNA replication cell division attachment of mitotic spindle microtubules to kinetochore kinetochore organization DNA polymerase binding DNA replication preinitiation complex assembly DNA replication preinitiation complex assembly response to sorbitol deactivation of mitotic spindle assembly checkpoint regulation of DNA replication origin binding negative regulation of protein localization to kinetochore positive regulation of protein localization to kinetochore positive regulation of DNA-dependent DNA replication |
|
| TC0100001244.mm.2 |
Ptpn7 |
protein tyrosine phosphatase, non-receptor type 7 |
1 |
135133308, 135132699 |
NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190 NM_177081, BC098475, BC138194, BC145190 |
320139 |
17 |
phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity cytoplasm cytosol cytoskeleton protein dephosphorylation protein dephosphorylation cytoplasmic side of plasma membrane microtubule cytoskeleton dephosphorylation hydrolase activity phosphatase activity mitotic spindle |
04010 |
| TC0900001979.mm.2 |
Aplp2 |
amyloid beta (A4) precursor-like protein 2 |
9 |
-31149556 |
NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 NM_001102455, NM_001102456, NM_009691, BC051999, BC052396 |
11804 |
111 |
suckling behavior DNA binding protein binding nucleus plasma membrane cellular copper ion homeostasis regulation of epidermal growth factor-activated receptor activity mating behavior locomotory behavior heparin binding cholesterol metabolic process embryo development membrane integral component of membrane extracellular matrix organization forebrain development midbrain development identical protein binding regulation of protein binding metal ion binding transition metal ion binding neuromuscular process controlling balance |
|
| TC1300001634.mm.2 |
H2ac8 |
H2A clustered histone 8 |
13 |
-23570662 |
NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498 |
319166 |
12 |
DNA binding nucleus chromatin silencing enzyme binding |
05322 |
| TC0X00003361.mm.2 |
Prps2 |
phosphoribosyl pyrophosphate synthetase 2 |
X |
-167346319 |
NM_026662, BC024942 NM_026662, BC024942 |
110639 |
23 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex identical protein binding ADP binding cellular biosynthetic process metal ion binding |
00030 00230 01100 |
| TC1700002414.mm.2 |
Rab31 |
RAB31, member RAS oncogene family |
17 |
-65651725 |
NM_133685, BC013063 NM_133685, BC013063 |
106572 |
25 |
nucleotide binding phagocytic cup GTPase activity protein binding GTP binding cytoplasm endosome early endosome late endosome Golgi apparatus trans-Golgi network intracellular protein transport endomembrane system membrane GDP binding cytoplasmic vesicle receptor internalization trans-Golgi network membrane trans-Golgi network membrane cellular response to insulin stimulus early phagosome membrane Golgi to plasma membrane protein transport Golgi to plasma membrane protein transport regulated exocytosis phagocytic vesicle Golgi vesicle transport positive regulation of phagocytosis, engulfment phagosome maturation |
04144 |
| TC1600001308.mm.2 |
Ranbp1 |
RAN binding protein 1 |
16 |
-18239978 |
NM_011239, BC061140 NM_011239, BC061140 |
19385 |
59 |
GDP-dissociation inhibitor activity GTPase activator activity nucleus nuclear pore cytoplasm cytoplasm cytoplasm centrosome centrosome cytosol spindle organization positive regulation of neuron projection development plasma membrane bounded cell projection cytoplasm positive regulation of mitotic centrosome separation positive regulation of mitotic centrosome separation intracellular transport cellular response to leptomycin B axon cytoplasm |
|
| TC0X00001272.mm.2 |
|
|
|
|
NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719 |
|
|
nucleic acid binding RNA binding mRNA binding nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA polyadenylation mRNA processing nuclear body mRNA 3'-end processing cleavage body pre-mRNA cleavage required for polyadenylation |
|
| TC0500002420.mm.2 |
Sel1l3 |
sel-1 suppressor of lin-12-like 3 (C. elegans) |
5 |
-53107082 |
NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916 NM_172710, BC094607, BC117915, BC117916 |
231238 |
18 |
molecular_function nucleoplasm biological_process membrane integral component of membrane |
|
| TC0500001648.mm.2 |
Nxpe5 |
neurexophilin and PC-esterase domain family, member 5 |
5 |
138225903 |
NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195 |
381680 |
10 |
molecular_function cellular_component biological_process |
|
| TC0400003349.mm.2 |
Mmachc |
methylmalonic aciduria cblC type, with homocystinuria |
4 |
-116702433 |
NM_025962, BC054756 NM_025962, BC054756 |
67096 |
21 |
cytoplasm cytoplasm mitochondrion glutathione metabolic process cobalamin metabolic process cobalamin metabolic process oxidoreductase activity transferase activity cobalamin binding demethylase activity demethylase activity cyanocobalamin reductase (cyanide-eliminating) activity cyanocobalamin reductase (cyanide-eliminating) activity protein homodimerization activity glutathione binding demethylation FAD binding FAD binding |
04977 |
| TC0800003249.mm.2 |
Emc8 |
ER membrane protein complex subunit 8 |
8 |
-120653913 |
NM_010926, BC009103 NM_010926, BC009103 |
18117 |
21 |
cytoplasm mitochondrion cytosol membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane EMC complex EMC complex |
|
| TC0100003204.mm.2 |
Rgs2 |
regulator of G-protein signaling 2 |
1 |
-143999337 |
NM_009061, BC023001 NM_009061, BC023001 |
19735 |
111 |
G-protein alpha-subunit binding GTPase activator activity GTPase activator activity protein binding nucleus nucleus cytoplasm cytosol cytosol plasma membrane plasma membrane regulation of translation cell cycle G protein-coupled receptor signaling pathway spermatogenesis regulation of G protein-coupled receptor signaling pathway cytoplasmic side of plasma membrane cytoplasmic side of plasma membrane negative regulation of signal transduction negative regulation of phospholipase activity negative regulation of cardiac muscle hypertrophy positive regulation of neuron projection development membrane negative regulation of translation neuron projection negative regulation of MAP kinase activity negative regulation of cAMP-mediated signaling negative regulation of G protein-coupled receptor signaling pathway negative regulation of G protein-coupled receptor signaling pathway beta-tubulin binding brown fat cell differentiation relaxation of cardiac muscle relaxation of vascular associated smooth muscle positive regulation of cardiac muscle contraction negative regulation of cell growth involved in cardiac muscle cell development negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process negative regulation of glycine import across plasma membrane |
|
| TC0800000972.mm.2 |
|
|
|
|
NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 NM_010062, NR_103491, BC058609, XR_106146, BC060661 |
|
|
DNA catabolic process, endonucleolytic nuclease activity endonuclease activity endodeoxyribonuclease activity deoxyribonuclease II activity deoxyribonuclease II activity lysosome DNA metabolic process DNA catabolic process apoptotic DNA fragmentation apoptotic process multicellular organism development hydrolase activity erythrocyte differentiation regulation of immune response |
|
| TC0900001302.mm.2 |
Topbp1 |
topoisomerase (DNA) II binding protein 1 |
9 |
103305326 |
NM_176979, BC049797 NM_176979, BC049797 |
235559 |
50 |
condensed nuclear chromosome male germ cell nucleus DNA binding nucleus nucleoplasm chromosome chromosome cytoplasm cytoskeleton plasma membrane DNA replication initiation DNA repair cellular response to DNA damage stimulus mitotic G2 DNA damage checkpoint reciprocal meiotic recombination response to ionizing radiation actin cytoskeleton nuclear body PML body mitotic DNA replication checkpoint identical protein binding intracellular membrane-bounded organelle |
|
| TC0800001541.mm.2 |
Urb2 |
URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
8 |
124021496 |
NM_001029876, BC151125 NM_001029876, BC151125 |
382038 |
13 |
molecular_function nucleolus nucleolus aggresome midbody ribosome biogenesis |
|
| TC0700001871.mm.2 |
Fus |
fused in sarcoma |
7 |
127967478 |
NM_139149, BC040827, BC058247 NM_139149, BC040827, BC058247 NM_139149, BC040827, BC058247 |
233908 |
143 |
transcription coregulator activity RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm polysome RNA splicing gene expression gene expression estrogen receptor binding dendrite myosin V binding ionotropic glutamate receptor binding neuronal cell body dendritic spine perikaryon dendritic spine head retinoid X receptor binding thyroid hormone receptor binding mRNA stabilization perinuclear region of cytoplasm cellular response to calcium ion |
|
| TC1500001585.mm.2 |
Mtss1 |
MTSS I-BAR domain containing 1 |
15 |
-58941233 |
NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131 |
211401 |
51 |
in utero embryonic development actin binding actin monomer binding signaling receptor binding protein binding cytoplasm cytoskeleton adherens junction plasma membrane organization actin filament organization nervous system development muscle organ development magnesium ion homeostasis actin cytoskeleton actin cytoskeleton organization actin filament polymerization bone mineralization positive regulation of actin filament bundle assembly adherens junction maintenance identical protein binding identical protein binding negative regulation of epithelial cell proliferation actin filament binding renal tubule morphogenesis cellular response to fluid shear stress glomerulus morphogenesis nephron tubule epithelial cell differentiation metanephric tubule development epithelial cell proliferation involved in renal tubule morphogenesis |
|
| TC0800001031.mm.2 |
Adcy7 |
adenylate cyclase 7 |
8 |
88282991, 88289065, 88272402, 88294203 |
NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 NM_001037723, NM_001037724, NM_001109756, NM_007406, BC115833 |
11513 |
30 |
nucleotide binding regulation of adaptive immune response adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane integral component of plasma membrane cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity cyclic nucleotide biosynthetic process membrane integral component of membrane lyase activity phosphorus-oxygen lyase activity intracellular signal transduction metal ion binding cellular response to lithium ion cellular response to ethanol negative regulation of cytokine production involved in inflammatory response |
00230 04020 04062 04114 04270 04540 04912 04914 04916 04970 04971 04972 04976 05414 |
| TC1100002069.mm.2 |
Metrnl |
meteorin, glial cell differentiation regulator-like |
11 |
121702426 |
NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 NM_144797, BC019776, BC024445, BC024497, BC026646 |
210029 |
27 |
hormone activity hormone activity extracellular region extracellular space extracellular space extracellular space response to cold response to muscle activity fat cell differentiation negative regulation of inflammatory response brown fat cell differentiation positive regulation of brown fat cell differentiation positive regulation of brown fat cell differentiation energy homeostasis energy homeostasis |
|
| TC1900000312.mm.2 |
Prune2 |
prune homolog 2 |
19 |
16956117 |
NM_181348, BC095978 NM_181348, BC095978 |
353211 |
29 |
exopolyphosphatase activity cytoplasm polyphosphate catabolic process apoptotic process pyrophosphatase activity |
|
| TC1300002269.mm.2 |
Mtrr |
5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
13 |
-68560779, -68560779 |
NM_172480, BC025942 NM_172480, BC025942 |
210009 |
26 |
NADPH-hemoprotein reductase activity nucleoplasm cytoplasm cytosol cytosol DNA methylation cellular amino acid biosynthetic process methionine biosynthetic process methionine biosynthetic process methionine biosynthetic process FMN binding FMN binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [methionine synthase] reductase activity [methionine synthase] reductase activity [methionine synthase] reductase activity S-adenosylmethionine cycle homocysteine catabolic process intermediate filament cytoskeleton folic acid metabolic process folic acid metabolic process flavin adenine dinucleotide binding flavin adenine dinucleotide binding homocysteine metabolic process homocysteine metabolic process protein stabilization NADPH binding FAD binding negative regulation of cystathionine beta-synthase activity |
|
| TC1400001783.mm.2 |
Tspan14 |
tetraspanin 14 |
14 |
-40906426, -40906426 |
NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574 NM_145928, BC024611, BC025568, BC026574 |
52588 |
24 |
plasma membrane integral component of plasma membrane cell surface membrane integral component of membrane enzyme binding enzyme binding positive regulation of Notch signaling pathway protein maturation protein maturation protein localization to plasma membrane tetraspanin-enriched microdomain |
|
| TC0900001101.mm.2 |
Ttk |
Ttk protein kinase |
9 |
83834688, 83834688 |
NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 |
22137 |
34 |
nucleotide binding kinetochore kinetochore protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm spindle protein phosphorylation chromosome segregation mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint membrane kinase activity phosphorylation female meiosis chromosome segregation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation meiotic spindle assembly checkpoint meiotic spindle assembly checkpoint protein localization to kinetochore protein localization to kinetochore protein localization to chromosome identical protein binding kinetochore binding protein autophosphorylation chromosome separation meiotic prometaphase I protein localization to meiotic spindle midzone |
04110 |
| TC0500001894.mm.2 |
Cyp51 |
cytochrome P450, family 51 |
5 |
-4080673 |
NM_020010, BC031813 NM_020010, BC031813 |
13121 |
55 |
monooxygenase activity iron ion binding endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process sterol 14-demethylase activity sterol 14-demethylase activity membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding cholesterol biosynthetic process via 24,25-dihydrolanosterol negative regulation of protein catabolic process intracellular membrane-bounded organelle metal ion binding negative regulation of protein secretion negative regulation of amyloid-beta clearance |
00100 01100 |
| TC0300003221.mm.2 |
Wdr77 |
WD repeat domain 77 |
3 |
105959497 |
NM_027432, BC005755 NM_027432, BC005755 |
70465 |
39 |
protein binding nucleus nucleoplasm nucleoplasm cytoplasm Golgi apparatus cytosol cytosol regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II pole plasm assembly positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation methyl-CpG binding methyl-CpG binding nuclear receptor coactivator activity nuclear receptor coactivator activity methylosome methylosome pole plasm secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development negative regulation of epithelial cell proliferation involved in prostate gland development negative regulation of epithelial cell proliferation involved in prostate gland development |
|
| TC1800001087.mm.2 |
Tpgs2 |
tubulin polyglutamylase complex subunit 2 |
18 |
-25136038, -25127222, -25136038 |
NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 |
66648 |
19 |
molecular_function cellular_component cytoplasm cytosol cytoskeleton microtubule biological_process protein polyglutamylation protein polyglutamylation |
|
| TC0100003478.mm.2 |
Uck2 |
uridine-cytidine kinase 2 |
1 |
-167226083 |
NM_030724, BC023789 NM_030724, BC023789 |
80914 |
24 |
nucleotide binding uridine kinase activity protein binding ATP binding cytoplasm cytosol cytosol CMP salvage phosphorylation transferase activity nucleoside kinase activity identical protein binding intracellular membrane-bounded organelle UMP salvage |
00240 00983 01100 |
| TC0700004363.mm.2 |
Rgs10 |
regulator of G-protein signalling 10 |
7 |
-128373624 |
NM_026418, BC109178 NM_026418, BC109178 |
67865 |
37 |
G-protein alpha-subunit binding GTPase activator activity protein binding nucleus cytoplasm cytosol G protein-coupled acetylcholine receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction neuronal cell body dendritic spine positive regulation of GTPase activity axon terminus |
|
| TC1100001973.mm.2 |
Birc5 |
baculoviral IAP repeat-containing 5 |
11 |
117849236 |
NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702 |
11799 |
215 |
G2/M transition of mitotic cell cycle microtubule cytoskeleton organization nuclear chromosome mitotic cytokinesis chromosome, centromeric region kinetochore condensed chromosome kinetochore cysteine-type endopeptidase inhibitor activity protein binding nucleus nucleus chromosome cytoplasm cytoplasm cytoplasm centriole cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cytoplasmic microtubule protein phosphorylation apoptotic process cell cycle chromosome segregation mitotic spindle assembly checkpoint regulation of mitotic cell cycle microtubule binding zinc ion binding embryo development negative regulation of peptidase activity tubulin binding apical plasma membrane enzyme binding peptidase inhibitor activity midbody interphase microtubule organizing center small GTPase binding protein-containing complex localization positive regulation of exit from mitosis chromosome passenger complex protein-containing complex identical protein binding protein homodimerization activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process positive regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of mitotic cell cycle metal ion binding protein heterodimerization activity chaperone binding cell division establishment of chromosome localization regulation of cell cycle regulation of insulin secretion involved in cellular response to glucose stimulus regulation of type B pancreatic cell proliferation |
05200 05210 |
| TC0900001652.mm.2 |
Kif15 |
kinesin family member 15 |
9 |
122951080 |
NM_010620, BC060710 NM_010620, BC060710 |
209737 |
26 |
nucleotide binding microtubule motor activity ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding ATPase activity |
|
| TC1500002217.mm.2 |
Racgap1 |
Rac GTPase-activating protein 1 |
15 |
-99620495 |
NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 |
26934 |
52 |
mitotic cytokinesis actomyosin contractile ring assembly GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleoplasm cytoplasm spindle cytoskeleton plasma membrane ion transport cell cycle signal transduction multicellular organism development spermatogenesis neuroblast proliferation microtubule binding sulfate transport lipid binding membrane protein kinase binding cell differentiation midbody extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cleavage furrow positive regulation of cytokinesis intracellular signal transduction alpha-tubulin binding gamma-tubulin binding regulation of embryonic development metal ion binding beta-tubulin binding spindle midzone mitotic spindle midzone assembly cell division regulation of attachment of spindle microtubules to kinetochore mitotic spindle centralspindlin complex |
|
| TC0600003373.mm.2 |
Recql |
RecQ protein-like |
6 |
-142350341, -142361375, -142356946, -142361375 |
NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735 NM_001204906, NM_001204907, NM_023042, BC014735 |
19691 |
21 |
nucleotide binding double-strand break repair via homologous recombination DNA strand renaturation nucleic acid binding DNA binding DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome cytoplasm DNA unwinding involved in DNA replication DNA repair DNA recombination four-way junction helicase activity hydrolase activity DNA duplex unwinding annealing helicase activity annealing helicase activity 3'-5' DNA helicase activity |
|
| TC1200000647.mm.2 |
Prkch |
protein kinase C, eta |
12 |
73584795 |
NM_008856, BC031121 NM_008856, BC031121 |
18755 |
43 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-independent protein kinase C activity protein binding ATP binding cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction protein phosphorylation positive regulation of macrophage derived foam cell differentiation membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation enzyme binding cell differentiation small GTPase binding negative regulation of glial cell apoptotic process intracellular signal transduction positive regulation of keratinocyte differentiation metal ion binding positive regulation of B cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity positive regulation of glial cell proliferation protein kinase C signaling regulation of bicellular tight junction assembly |
04270 04530 |
| TC0600000788.mm.2 |
Serbp1 |
serpine1 mRNA binding protein 1 |
6 |
67266978 |
NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 |
66870 |
38 |
RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleus cytoplasm cytoplasm cytosol PML body organization SUMO binding |
|
| TC1300001353.mm.2 |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 |
13 |
119690350 |
NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 |
208715 |
44 |
catalytic activity hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity cytoplasm cytosol cytosol acetyl-CoA metabolic process lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process farnesyl diphosphate biosynthetic process, mevalonate pathway response to purine-containing compound sterol biosynthetic process transferase activity isomerase activity small molecule binding protein homodimerization activity organic acid binding cellular response to low-density lipoprotein particle stimulus |
00072 00280 00650 00900 01100 |
| TC0300002203.mm.2 |
Tmem144 |
transmembrane protein 144 |
3 |
-79812563, -79812563, -79812563, -79812563 |
NM_027495, BC018493 NM_027495, BC018493 |
70652 |
11 |
molecular_function cellular_component biological_process carbohydrate transmembrane transporter activity membrane integral component of membrane carbohydrate transmembrane transport |
|
| TC1500000053.mm.2 |
Nup155 |
nucleoporin 155 |
15 |
8109312 |
NM_133227, BC050919 NM_133227, BC050919 |
170762 |
28 |
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear envelope nuclear pore cytoplasm RNA export from nucleus mRNA export from nucleus protein import into nucleus protein import into nucleus nucleocytoplasmic transport nuclear envelope organization protein transport membrane structural constituent of nuclear pore nuclear membrane protein localization to nuclear inner membrane nuclear pore inner ring mRNA transport atrial cardiac muscle cell action potential |
03013 |
| TC0300000586.mm.2 |
Nmd3 |
NMD3 ribosome export adaptor |
3 |
69722054 |
NM_133787, BC003842, NMD3(S NM_133787, BC003842, NMD3(S NM_133787, BC003842, NMD3(S |
97112 |
20 |
ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm protein transport protein-macromolecule adaptor activity positive regulation of protein binding ribosomal large subunit binding ribosomal large subunit binding positive regulation of RNA biosynthetic process positive regulation of protein localization to nucleolus |
03008 03013 |
| TC0800003233.mm.2 |
Trmt1 |
tRNA methyltransferase 1 |
8 |
84689283, 84689246, 84686323 |
NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 |
212528 |
21 |
tRNA binding tRNA N2-guanine methylation RNA binding tRNA (guanine-N2-)-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity nucleus tRNA processing methyltransferase activity transferase activity methylation metal ion binding |
|
| TC1800000704.mm.2 |
Tubb6 |
tubulin, beta 6 class V |
18 |
67390730 |
NM_026473, BC008225 NM_026473, BC008225 |
67951 |
38 |
nucleotide binding microtubule cytoskeleton organization mitotic cell cycle GTPase activity structural constituent of cytoskeleton GTP binding cytoplasm cytoskeleton microtubule microtubule microtubule-based process |
04145 04540 |
| TC0800000987.mm.2 |
Orc6 |
origin recognition complex, subunit 6 |
8 |
85299631 |
NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 |
56452 |
21 |
origin recognition complex fibrillar center DNA binding nucleus nucleoplasm nuclear origin of replication recognition complex DNA replication DNA-dependent DNA replication DNA replication initiation negative regulation of cell division |
04110 |
| TC0500001865.mm.2 |
Brca2 |
breast cancer 2, early onset |
5 |
150522620 |
NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649 |
12190 |
178 |
telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region lateral element oocyte maturation inner cell mass cell proliferation protease binding DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton DNA repair nucleotide-excision repair double-strand break repair double-strand break repair DNA recombination regulation of transcription, DNA-templated cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle male meiosis I male meiosis I spermatogenesis spermatogenesis brain development cell aging protein C-terminus binding cell population proliferation female gonad development intrinsic apoptotic signaling pathway in response to DNA damage response to X-ray response to UV-C response to gamma radiation H3 histone acetyltransferase activity H4 histone acetyltransferase activity hemopoiesis secretory granule mammary gland development homologous chromosome orientation involved in meiotic metaphase I plate congression regulation of cytokinesis protein-containing complex BRCA2-MAGE-D1 complex negative regulation of mammary gland epithelial cell proliferation multicellular organism growth intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding chordate embryonic development gamma-tubulin binding histone H3 acetylation histone H4 acetylation positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle replication fork protection chromosome organization centrosome duplication establishment of protein localization to telomere establishment of protein localization to telomere mitotic recombination-dependent replication fork processing |
03440 05200 05212 |
| TC1100004296.mm.2 |
Nme1 |
NME/NM23 nucleoside diphosphate kinase 1 |
11 |
-93958924, -93958924 |
NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23 |
18102 |
75 |
nucleotide binding magnesium ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding negative regulation of myeloid leukocyte differentiation single-stranded DNA binding deoxyribonuclease activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding GTP binding nucleus cytoplasm mitochondrion mitochondrial outer membrane centrosome cytosol intermediate filament nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process endocytosis nervous system development lactation nucleotide metabolic process negative regulation of gene expression positive regulation of neuron projection development membrane kinase activity phosphorylation transferase activity intermediate filament binding enzyme binding protein kinase binding cell differentiation mammary gland development ruffle membrane identical protein binding gamma-tubulin binding ribosomal small subunit binding myelin sheath positive regulation of DNA binding metal ion binding perinuclear region of cytoplasm positive regulation of epithelial cell proliferation |
00230 00240 01100 |
| TC0700004451.mm.2 |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
7 |
-135689787 |
NM_001081117 |
17345 |
1917 |
nucleotide binding chromosome, centromeric region condensed chromosome condensed chromosome DNA binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm cell cycle regulation of mitotic nuclear division protein C-terminus binding cell population proliferation nuclear body meiotic cell cycle regulation of chromosome segregation hepatocyte proliferation regulation of chromatin organization cholangiocyte proliferation |
|
| TC1400002057.mm.2 |
Prmt5 |
protein arginine N-methyltransferase 5 |
14 |
-54507181 |
NM_013768, BC023905 NM_013768, BC023905 |
27374 |
104 |
negative regulation of transcription by RNA polymerase II spliceosomal snRNP assembly p53 binding chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm Golgi apparatus cytosol cytosol chromatin organization DNA-templated transcription, termination regulation of transcription, DNA-templated protein methylation methyltransferase activity methyl-CpG binding histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation methylation circadian regulation of gene expression protein-containing complex methylosome histone arginine methylation histone methyltransferase complex histone methyltransferase complex protein-arginine omega-N symmetric methyltransferase activity peptidyl-arginine N-methylation endothelial cell activation identical protein binding ribonucleoprotein complex binding histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) regulation of DNA methylation protein-containing complex binding negative regulation of cell differentiation protein heterodimerization activity rhythmic process positive regulation of oligodendrocyte differentiation regulation of ERK1 and ERK2 cascade E-box binding Golgi ribbon formation positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway |
03013 |
| TC0800000146.mm.2 |
Cln8 |
CLN8 transmembrane ER and ERGIC protein |
8 |
14888535 |
NM_012000, BC021625 NM_012000, BC021625 |
26889 |
85 |
age-dependent response to oxidative stress protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment phospholipid metabolic process phospholipid metabolic process phospholipid metabolic process ceramide metabolic process mitochondrial membrane organization lysosome organization nervous system development nervous system development visual perception adult walking behavior cholesterol metabolic process associative learning adult locomotory behavior regulation of cell size membrane integral component of membrane spinal cord motor neuron differentiation somatic motor neuron differentiation social behavior negative regulation of apoptotic process cellular protein catabolic process cellular macromolecule catabolic process cellular protein metabolic process photoreceptor cell maintenance musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate reuptake lipid homeostasis retina development in camera-type eye neurofilament cytoskeleton organization ceramide binding ceramide binding |
|
| TC0400002457.mm.2 |
Nol6 |
nucleolar protein family 6 (RNA-associated) |
4 |
-41114426 |
NM_139236, BC059820 NM_139236, BC059820 |
230082 |
24 |
condensed nuclear chromosome RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus mitochondrion rRNA processing tRNA export from nucleus small-subunit processome CURI complex UTP-C complex |
03008 |
| TC1000003152.mm.2 |
Pa2g4 |
proliferation-associated 2G4 |
10 |
-128557765 |
NM_011119, BC046532 NM_011119, BC046532 |
18813 |
52 |
nucleic acid binding transcription corepressor activity RNA binding nucleus nucleolus cytoplasm rRNA processing regulation of translation ubiquitin protein ligase binding negative regulation of apoptotic process positive regulation of cell differentiation negative regulation of transcription, DNA-templated ribonucleoprotein complex |
|
| TC1300000033.mm.2 |
Pitrm1 |
pitrilysin metallepetidase 1 |
13 |
6548156, 6548156 |
NM_145131, BC006917 NM_145131, BC006917 |
69617 |
28 |
catalytic activity metalloendopeptidase activity metalloendopeptidase activity mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix proteolysis peptidase activity metallopeptidase activity zinc ion binding protein processing hydrolase activity metal ion binding |
|
| TC0800003236.mm.2 |
Usp10 |
ubiquitin specific peptidase 10 |
8 |
119910359 |
NM_009462, BC007134 NM_009462, BC007134 |
22224 |
38 |
p53 binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity nucleus nucleus nucleoplasm cytoplasm endosome early endosome early endosome cytosol cytosol DNA repair ubiquitin-dependent protein catabolic process autophagy cellular response to DNA damage stimulus peptidase activity cysteine-type peptidase activity regulation of autophagy regulation of autophagy protein deubiquitination protein deubiquitination hydrolase activity DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator protein-containing complex negative regulation of I-kappaB kinase/NF-kappaB signaling ion channel binding intermediate filament cytoskeleton cellular response to interleukin-1 |
|
| TC0400002222.mm.2 |
Cibar1 |
CBY1 interacting BAR domain containing 1 |
4 |
-12153141 |
NM_026558, BC020162 NM_026558, BC020162 |
68099 |
19 |
protein binding phospholipid binding nucleus cytoplasm mitochondrial inner membrane centriole cytoskeleton cilium inner mitochondrial membrane organization cell projection organization limb morphogenesis limb morphogenesis ciliary transition zone ciliary basal body cell projection positive regulation of smoothened signaling pathway cilium assembly cilium assembly membrane organization ciliary base |
|
| TC0600000648.mm.2 |
Chn2 |
chimerin 2 |
6 |
54039931, 54272821, 54269155, 54264857 |
NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 |
69993 |
32 |
GTPase activator activity GTPase activator activity signal transduction membrane intracellular signal transduction regulation of GTPase activity synapse metal ion binding |
|
| TC1400001314.mm.2 |
Ipo5 |
importin 5 |
14 |
120915846, 120911193 |
NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814 |
70572 |
40 |
protein binding nucleus nucleus cytoplasm cytoplasm protein import into nucleus NLS-bearing protein import into nucleus ribosomal protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding positive regulation of protein import into nucleus nuclear import signal receptor activity nuclear import signal receptor activity cellular response to amino acid stimulus |
|
| TC1700000777.mm.2 |
Olfr111 |
olfactory receptor 111 |
17 |
37529956 |
NM_001005485, BC139116, BC139117 NM_001005485, BC139116, BC139117 NM_001005485, BC139116, BC139117 |
545205 |
6 |
olfactory receptor activity G protein-coupled receptor signaling pathway sensory perception of smell integral component of membrane |
|
| TC1900000212.mm.2 |
Prpf19 |
pre-mRNA processing factor 19 |
19 |
10898644, 10895230 |
NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 |
28000 |
38 |
protein polyubiquitination spliceosomal tri-snRNP complex assembly spliceosomal complex assembly generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome Prp19 complex Prp19 complex inner cell mass cell proliferation ubiquitin-protein transferase activity protein binding nucleus nucleus DNA replication factor A complex spliceosomal complex cytoplasm cytoplasm lipid droplet cytoskeleton DNA repair double-strand break repair via nonhomologous end joining mRNA processing cellular response to DNA damage stimulus RNA splicing lipid biosynthetic process proteasomal protein catabolic process proteasomal protein catabolic process nuclear speck transferase activity ubiquitin-ubiquitin ligase activity cellular protein localization site of double-strand break identical protein binding negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of mRNA splicing, via spliceosome positive regulation of astrocyte differentiation positive regulation of astrocyte differentiation ubiquitin protein ligase activity protein K63-linked ubiquitination U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome signal transduction involved in DNA damage checkpoint |
03040 04120 |
| TC0100001858.mm.2 |
Nek2 |
NIMA (never in mitosis gene a)-related expressed kinase 2 |
1 |
191821472 |
NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 |
18005 |
48 |
mitotic sister chromatid segregation nucleotide binding chromosome, centromeric region kinetochore condensed nuclear chromosome spindle pole blastocyst development protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cytoskeleton microtubule protein phosphorylation protein phosphorylation cell cycle chromosome segregation chromosome segregation chromosome segregation kinase activity phosphorylation transferase activity protein phosphatase binding midbody positive regulation of telomere maintenance via telomerase protein-containing complex negative regulation of DNA binding regulation of mitotic centrosome separation protein autophosphorylation metal ion binding centrosome separation cell division meiotic cell cycle positive regulation of telomerase activity regulation of attachment of spindle microtubules to kinetochore mitotic spindle assembly negative regulation of centriole-centriole cohesion positive regulation of telomere capping |
|
| TC0400003633.mm.2 |
Nkain1 |
Na+/K+ transporting ATPase interacting 1 |
4 |
-130530130 |
NM_025998, BC116391 NM_025998, BC116391 |
67149 |
18 |
regulation of sodium ion transport plasma membrane membrane integral component of membrane ATPase binding |
|
| TC0100003280.mm.2 |
Npl |
N-acetylneuraminate pyruvate lyase |
1 |
-153503015 |
NM_028749, BC022734 NM_028749, BC022734 |
74091 |
23 |
catalytic activity cellular_component cytoplasm carbohydrate metabolic process N-acetylneuraminate lyase activity N-acetylneuraminate lyase activity lyase activity N-acetylneuraminate catabolic process identical protein binding |
00520 |
| TC1800001083.mm.2 |
Slc39a6 |
solute carrier family 39 (metal ion transporter), member 6 |
18 |
-24579880 |
NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012 |
106957 |
27 |
zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity endoplasmic reticulum plasma membrane integral component of plasma membrane integral component of plasma membrane ion transport zinc ion transport cellular zinc ion homeostasis cellular zinc ion homeostasis membrane integral component of membrane metal ion transport lamellipodium membrane metal ion transmembrane transporter activity transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane |
|
| TC0100002308.mm.2 |
Myo1b |
myosin IB |
1 |
-51749757 |
NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 |
17912 |
41 |
microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding calmodulin binding ATP binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytoplasm early endosome actin filament plasma membrane plasma membrane microvillus brush border brush border brush border post-Golgi vesicle-mediated transport actin filament organization actin filament organization endosome membrane actin cytoskeleton myosin complex actin filament-based movement vesicle transport along actin filament filopodium actin-dependent ATPase activity actin-dependent ATPase activity vesicle trans-Golgi network membrane transferrin transport apical part of cell perinuclear region of cytoplasm actin filament binding actin filament binding actin filament bundle assembly cell periphery |
|
| TC1300001751.mm.2 |
Gmds |
GDP-mannose 4, 6-dehydratase |
13 |
-31819585 |
NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502 |
218138 |
21 |
cytoplasm GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process |
00051 00520 01100 |
| TC0900000505.mm.2 |
H2ax |
H2A.X variant histone |
9 |
44334714 |
NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, |
15270 |
476 |
double-strand break repair via homologous recombination chromosome, telomeric region chromatin nucleosome condensed nuclear chromosome male germ cell nucleus XY body DNA binding damaged DNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome centrosome DNA repair DNA repair DNA recombination chromatin silencing cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle spermatogenesis nuclear speck enzyme binding site of double-strand break site of double-strand break histone binding protein heterodimerization activity meiotic cell cycle cellular response to gamma radiation site of DNA damage |
05322 |
| TC1500000736.mm.2 |
Xrcc6 |
X-ray repair complementing defective repair in Chinese hamster cells 6 |
15 |
82016368 |
NM_010247, BC031422 NM_010247, BC031422 |
14375 |
137 |
nucleotide binding telomere maintenance transcription regulatory region sequence-specific DNA binding activation of innate immune response immune system process DNA binding DNA helicase activity damaged DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded telomeric DNA binding catalytic activity helicase activity protein binding ATP binding nucleus nucleus nucleoplasm transcription regulator complex chromosome nucleolus cytoplasm cytoplasm DNA repair double-strand break repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining DNA recombination cellular response to DNA damage stimulus protein C-terminus binding DNA-dependent ATPase activity metabolic process response to ionizing radiation hydrolase activity lyase activity cyclin binding protein-containing complex protein-DNA complex V(D)J recombination telomeric DNA binding Ku70:Ku80 complex Ku70:Ku80 complex protein-containing complex binding DNA end binding innate immune response positive regulation of lymphocyte differentiation positive regulation of protein kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of smooth muscle cell proliferation positive regulation of neurogenesis 5'-deoxyribose-5-phosphate lyase activity nonhomologous end joining complex cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to gamma radiation cellular response to X-ray cellular response to X-ray double-strand break repair via classical nonhomologous end joining |
03450 |
| TC1800000063.mm.2 |
Colec12 |
collectin sub-family member 12 |
18 |
9707647 |
NM_130449, BC057936 NM_130449, BC057936 |
140792 |
19 |
scavenger receptor activity collagen trimer phagocytosis, recognition phagocytosis, recognition immune response membrane integral component of membrane low-density lipoprotein particle binding low-density lipoprotein particle binding carbohydrate binding toll-like receptor 3 signaling pathway signaling receptor activity pattern recognition receptor activity pattern recognition receptor activity defense response to bacterium metal ion binding positive regulation of cell adhesion molecule production collagen-containing extracellular matrix |
04145 |
| TC0500002580.mm.2 |
Tec |
tec protein tyrosine kinase |
5 |
-72755717 |
NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 NM_001113460, NM_001113461, NM_001113464, NM_013689, BC037071, BC062884 |
21682 |
74 |
nucleotide binding adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane cell-cell junction protein phosphorylation integrin-mediated signaling pathway integrin-mediated signaling pathway lipid binding regulation of platelet activation regulation of platelet activation membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation intracellular signal transduction peptidyl-tyrosine autophosphorylation peptidyl-tyrosine autophosphorylation tissue regeneration metal ion binding positive regulation of peptidyl-tyrosine phosphorylation T cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway |
04380 04660 |
| TC0300000714.mm.2 |
Iqgap3 |
IQ motif containing GTPase activating protein 3 |
3 |
88082050 |
NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704 |
404710 |
20 |
G1/S transition of mitotic cell cycle activation of MAPK activity positive regulation of protein phosphorylation GTPase activator activity protein binding calmodulin binding calmodulin binding cytoplasm cytoplasm cell-cell junction Ras protein signal transduction regulation of cell size positive regulation of gene expression negative regulation of gene expression lateral plasma membrane small GTPase binding regulation of actin cytoskeleton organization positive regulation of mammary gland epithelial cell proliferation actin filament binding ERK1 and ERK2 cascade myosin VI light chain binding cellular response to organic substance |
04810 |
| TC1300000173.mm.2 |
H2ac13 |
H2A clustered histone 13 |
13 |
21716411 |
NM_178182, BC099406 NM_178182, BC099406 |
319191 |
16 |
DNA binding nucleus chromatin silencing negative regulation of cell population proliferation |
05322 |
| TC1800001138.mm.2 |
Stard4 |
StAR-related lipid transfer (START) domain containing 4 |
18 |
-33199137 |
NM_133774, BC005642 NM_133774, BC005642 |
170459 |
24 |
cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum cytosol cytosol lipid transport lipid binding positive regulation of cholesterol esterification cholesterol transport involved in cholesterol storage cholesterol transport involved in cholesterol storage cholesterol binding cholesterol binding cholesterol binding cytoplasmic vesicle intracellular cholesterol transport intracellular cholesterol transport cholesterol esterification cholesterol import cholesterol import positive regulation of bile acid biosynthetic process cholesterol transfer activity cholesterol transfer activity |
|
| TC0800001094.mm.2 |
Mt2 |
metallothionein 2 |
8 |
94172617 |
NM_008630, BC031758 NM_008630, BC031758 |
17750 |
217 |
nucleus cytoplasm cytosol cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding response to bacterium detoxification of copper ion detoxification of copper ion metal ion binding cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion |
|
| TC0800003059.mm.2 |
Slc7a5 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
8 |
-121881145 |
NM_011404, BC026131 NM_011404, BC026131 |
20539 |
56 |
amino acid transmembrane transport lysosome cytosol plasma membrane amino acid transport basal plasma membrane negative regulation of gene expression amino acid transmembrane transporter activity aromatic amino acid transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-leucine transmembrane transporter activity L-tryptophan transmembrane transporter activity thyroid hormone transmembrane transporter activity L-amino acid transport phenylalanine transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane transmembrane transporter activity microvillus membrane positive regulation of interferon-gamma production positive regulation of interleukin-17 production positive regulation of interleukin-4 production xenobiotic transport intracellular membrane-bounded organelle transmembrane transport thyroid hormone transport amino acid import across plasma membrane external side of apical plasma membrane leucine import across plasma membrane L-leucine import across plasma membrane L-tryptophan transmembrane transport amino acid transport complex |
|
| TC0400000913.mm.2 |
Mtap |
methylthioadenosine phosphorylase |
4 |
89137369 |
NM_024433, BC003858 NM_024433, BC003858 |
66902 |
37 |
catalytic activity nucleus nucleoplasm cytoplasm cytosol cytosol purine ribonucleoside salvage nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring pentosyl groups S-methyl-5-thioadenosine phosphorylase activity L-methionine salvage from methylthioadenosine methylation |
00270 01100 |
| TC1100003221.mm.2 |
Rpa1 |
replication protein A1 |
11 |
-75300258 |
NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119 |
68275 |
73 |
telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome lateral element male germ cell nucleus in utero embryonic development nucleic acid binding DNA binding chromatin binding damaged DNA binding damaged DNA binding single-stranded DNA binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA unwinding involved in DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination cellular response to DNA damage stimulus telomere maintenance via telomerase positive regulation of cell population proliferation PML body hemopoiesis protein localization to chromosome single-stranded telomeric DNA binding metal ion binding homeostasis of number of cells within a tissue chromosome organization meiotic cell cycle meiotic cell cycle site of DNA damage G-rich strand telomeric DNA binding |
03030 03420 03430 03440 |
| TC0600001807.mm.2 |
Pon3 |
paraoxonase 3 |
6 |
-5216255 |
NM_173006, BC099416 NM_173006, BC099416 |
269823 |
29 |
aryldialkylphosphatase activity arylesterase activity arylesterase activity extracellular region extracellular space extracellular space response to toxic substance phenylacetate catabolic process hydrolase activity 3,4-dihydrocoumarin hydrolase activity aromatic compound catabolic process negative regulation of superoxide anion generation protein homodimerization activity intracellular membrane-bounded organelle coumarin catabolic process carboxylic acid catabolic process metal ion binding acyl-L-homoserine-lactone lactonohydrolase activity |
01100 |
| TC1500000710.mm.2 |
Adsl |
adenylosuccinate lyase |
15 |
80948489 |
NM_009634, BC020187 NM_009634, BC020187 |
11564 |
34 |
catalytic activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity mitochondrion cytosol cytosol purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process response to nutrient aerobic respiration purine ribonucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process lyase activity protein-containing complex identical protein binding 'de novo' AMP biosynthetic process (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity |
00230 00250 01100 |
| TC0400003849.mm.2 |
Mrto4 |
mRNA turnover 4, ribosome maturation factor |
4 |
-139347439 |
NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 |
69902 |
26 |
ribosomal large subunit assembly nuclear-transcribed mRNA catabolic process intracellular anatomical structure nucleus nucleolus cytoplasm rRNA processing preribosome, large subunit precursor ribosome biogenesis ribosomal large subunit biogenesis |
|
| TC0X00001069.mm.2 |
Tlr13 |
toll-like receptor 13 |
X |
106143274 |
NM_205820, BC117913, BC117914 NM_205820, BC117913, BC117914 NM_205820, BC117913, BC117914 |
279572 |
31 |
toll-like receptor signaling pathway immune system process MyD88-dependent toll-like receptor signaling pathway RNA binding protein binding cytoplasm endosome integral component of plasma membrane inflammatory response signal transduction response to virus membrane integral component of membrane hydrolase activity rRNA binding toll-like receptor 13 signaling pathway signaling receptor activity identical protein binding regulation of MAPK cascade innate immune response NAD(P)+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating |
|
| TC0700004321.mm.2 |
Sephs2 |
selenophosphate synthetase 2 |
7 |
-127271878 |
NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 |
20768 |
20 |
nucleotide binding selenium compound metabolic process selenium compound metabolic process selenide, water dikinase activity selenide, water dikinase activity ATP binding cytoplasm selenocysteine biosynthetic process selenocysteine biosynthetic process kinase activity phosphorylation transferase activity metal ion binding |
00450 01100 |
| TC0700001951.mm.2 |
Dock1 |
dedicator of cytokinesis 1 |
7 |
134670686 |
NM_001033420 |
330662 |
46 |
hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleoplasm cytoplasm cytosol phagocytosis apoptotic process cytoskeleton organization small GTPase mediated signal transduction positive regulation of epithelial cell migration membrane cell migration nuclear speck SH3 domain binding guanyl-nucleotide exchange factor complex positive regulation of substrate adhesion-dependent cell spreading |
04510 04810 05100 |
| TC0700002999.mm.2 |
Cd37 |
CD37 antigen |
7 |
-45233631, -45233631 |
NM_007645, BC019402, CD37 NM_007645, BC019402, CD37 NM_007645, BC019402, CD37 |
12493 |
34 |
immunological synapse positive regulation of immunoglobulin production regulation of humoral immune response integral component of plasma membrane negative regulation of cell population proliferation membrane integral component of membrane negative regulation of myeloid dendritic cell activation defense response to protozoan regulation of defense response to virus |
04640 |
| TC0200002478.mm.2 |
Mybl2 |
myeloblastosis oncogene-like 2 |
2 |
163054634 |
NM_008652, BC050842 NM_008652, BC050842 |
17865 |
77 |
mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated Myb complex positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mitotic spindle assembly cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding |
|
| TC1900000718.mm.2 |
Pdcd11 |
programmed cell death 11 |
19 |
47090765 |
NM_011053, BC070468 NM_011053, BC070468 |
18572 |
30 |
nucleic acid binding RNA binding nucleus nucleolus cytosol rRNA processing RNA processing mRNA processing transcription factor binding small-subunit processome |
|
| TC0600002045.mm.2 |
|
|
|
|
NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 NM_009658, NR_037965, BC004725, BC021655, BC085310 |
|
|
retinoid metabolic process retinal dehydrogenase activity tissue homeostasis epithelial cell maturation renal water homeostasis alditol:NADP+ 1-oxidoreductase activity alditol:NADP+ 1-oxidoreductase activity alditol:NADP+ 1-oxidoreductase activity extracellular space nucleoplasm cytoplasm cytosol cytosol monosaccharide metabolic process sorbitol biosynthetic process response to water deprivation response to organic substance oxidoreductase activity naphthalene metabolic process stress-activated protein kinase signaling cascade plasma membrane bounded cell projection cytoplasm paranodal junction regulation of urine volume regulation of urine volume norepinephrine metabolic process mast cell granule negative regulation of apoptotic process Schmidt-Lanterman incisure glyceraldehyde oxidoreductase activity daunorubicin metabolic process doxorubicin metabolic process positive regulation of receptor signaling pathway via JAK-STAT allyl-alcohol dehydrogenase activity perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation NADP-retinol dehydrogenase activity cellular response to hydrogen peroxide cellular hyperosmotic salinity response inner medullary collecting duct development metanephric collecting duct development cellular response to methylglyoxal Schwann cell microvillus |
|
| TC1100000822.mm.2 |
Pmp22 |
peripheral myelin protein 22 |
11 |
63131456, 63128981, 63132568, 63132802 |
NM_008885, BC010765 NM_008885, BC010765 |
18858 |
199 |
motor activity protein binding plasma membrane plasma membrane bicellular tight junction autophagy immune response cell cycle cell cycle arrest cell adhesion peripheral nervous system development mating adult walking behavior cholesterol metabolic process cell death negative regulation of cell population proliferation integrin complex adult locomotory behavior response to bacterium cell surface multicellular organism aging regulation of gene expression proteasomal protein catabolic process regulation of Schwann cell proliferation positive regulation of gene expression negative regulation of gene expression fibroblast migration negative regulation of neuron projection development Schwann cell differentiation Schwann cell development membrane integral component of membrane transmission of nerve impulse transmission of nerve impulse neuronal action potential propagation neuronal action potential myelination in peripheral nervous system myelination in peripheral nervous system lamellipodium assembly actin cytoskeleton organization cell differentiation paranodal junction assembly membrane raft organization bleb assembly myelin assembly myelin assembly regulation of glial cell apoptotic process cellular response to heat cellular response to unfolded protein response to endoplasmic reticulum stress multicellular organism growth Schwann cell migration gliogenesis myelination myelination proteasome-mediated ubiquitin-dependent protein catabolic process compact myelin compact myelin laminin complex cellular lipid metabolic process neuronal ion channel clustering perinuclear region of cytoplasm muscle fiber development peripheral nervous system neuron axonogenesis regulation of inflammatory response neuromuscular process striated muscle cell differentiation cellular localization vestibular reflex axon development motor behavior aggresome assembly basement membrane organization regulation of protein serine/threonine kinase activity neuromuscular junction development, skeletal muscle fiber regulation of apoptotic signaling pathway |
|
| TC0500001399.mm.2 |
P2rx7 |
purinergic receptor P2X, ligand-gated ion channel, 7 |
5 |
122643926, 122643926, 122650382, 122643926 |
NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027, BC141120 |
18439 |
515 |
activation of MAPK activity cell morphogenesis lipopolysaccharide binding purinergic nucleotide receptor activity positive regulation of cytokine production phagolysosome assembly positive regulation of T cell mediated cytotoxicity positive regulation of protein phosphorylation extracellularly ATP-gated cation channel activity extracellularly ATP-gated cation channel activity extracellularly ATP-gated cation channel activity ion channel activity protein binding ATP binding integral component of nuclear inner membrane plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cell-cell junction protein phosphorylation membrane protein ectodomain proteolysis phospholipid transfer to membrane ion transport cation transport calcium ion transport cell volume homeostasis vesicle budding from membrane inflammatory response mitochondrion organization plasma membrane organization cell death cell death response to mechanical stimulus response to bacterium external side of plasma membrane response to organic substance response to zinc ion gene expression positive regulation of calcium ion transport into cytosol positive regulation of gene expression programmed cell death programmed cell death positive regulation of glutamate secretion positive regulation of gamma-aminobutyric acid secretion response to organic cyclic compound channel activity channel activity membrane membrane integral component of membrane synaptic vesicle exocytosis protein processing plasma membrane phospholipid scrambling sensory perception of pain protein catabolic process positive regulation of bone mineralization neuromuscular junction cellular response to extracellular stimulus bleb assembly bleb assembly positive regulation of prostaglandin secretion response to lipopolysaccharide response to lipopolysaccharide positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production collagen metabolic process response to ATP response to ATP response to ATP response to fluid shear stress positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway signaling receptor activity T cell proliferation response to drug identical protein binding neuronal cell body T cell homeostasis positive regulation of apoptotic process positive regulation of catalytic activity NAD transport negative regulation of MAPK cascade positive regulation of MAPK cascade synapse phospholipid translocation positive regulation of ossification negative regulation of bone resorption negative regulation of cell volume negative regulation of cell volume positive regulation of glycolytic process ceramide biosynthetic process pore complex assembly pore complex assembly skeletal system morphogenesis homeostasis of number of cells within a tissue positive regulation of protein secretion defense response to Gram-positive bacterium release of sequestered calcium ion into cytosol response to calcium ion response to calcium ion response to electrical stimulus membrane depolarization positive regulation of mitochondrial depolarization positive regulation of lymphocyte apoptotic process cellular response to dsRNA cellular response to organic cyclic compound reactive oxygen species metabolic process extrinsic apoptotic signaling pathway positive regulation of bleb assembly |
04020 04080 |
| TC1000001716.mm.2 |
Sash1 |
SAM and SH3 domain containing 1 |
10 |
-8722218 |
NM_175155, BC152995 NM_175155, BC152995 |
70097 |
22 |
protein polyubiquitination G-protein alpha-subunit binding cytoplasm protein C-terminus binding positive regulation of endothelial cell migration regulation of epithelial cell migration membrane protein kinase binding mitogen-activated protein kinase kinase kinase binding mitogen-activated protein kinase kinase kinase binding positive regulation of lipopolysaccharide-mediated signaling pathway protein-containing complex positive regulation of JUN kinase activity positive regulation of JUN kinase activity positive regulation of angiogenesis molecular adaptor activity regulation of protein K63-linked ubiquitination positive regulation of p38MAPK cascade positive regulation of NIK/NF-kappaB signaling positive regulation of NIK/NF-kappaB signaling regulation of protein autoubiquitination |
|
| TC1100003118.mm.2 |
C1qbp |
complement component 1, q subcomponent binding protein |
11 |
-70977845 |
NM_007573, BC038075 NM_007573, BC038075 |
12261 |
67 |
negative regulation of transcription by RNA polymerase II complement component C1q complex binding complement component C1q complex binding adaptive immune response immune system process transcription corepressor activity transcription corepressor activity mRNA binding mRNA binding protein kinase C binding protein binding hyaluronic acid binding hyaluronic acid binding extracellular region extracellular space nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol plasma membrane plasma membrane mRNA processing apoptotic process complement activation, classical pathway transcription factor binding transcription factor binding RNA splicing translation activator activity cell surface cell surface phosphatidylinositol 3-kinase signaling membrane regulation of complement activation regulation of complement activation kininogen binding kininogen binding adrenergic receptor binding negative regulation of interferon-gamma production negative regulation of interleukin-12 production negative regulation of MDA-5 signaling pathway negative regulation of RIG-I signaling pathway ribosome biogenesis mature ribosome assembly mature ribosome assembly mature ribosome assembly positive regulation of apoptotic process innate immune response positive regulation of cell adhesion negative regulation of mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome presynaptic active zone negative regulation of defense response to virus positive regulation of protein kinase B signaling positive regulation of mitochondrial translation positive regulation of mitochondrial translation positive regulation of neutrophil chemotaxis mitochondrial ribosome binding mitochondrial ribosome binding presynapse glutamatergic synapse GABA-ergic synapse positive regulation of substrate adhesion-dependent cell spreading positive regulation of trophoblast cell migration positive regulation of dendritic cell chemotaxis |
|
| TC0400002479.mm.2 |
Sigmar1 |
sigma non-opioid intracellular receptor 1 |
4 |
-41738492 |
NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014, BC002000, BC019930 |
18391 |
145 |
opioid receptor activity protein binding nucleus nuclear envelope endoplasmic reticulum endoplasmic reticulum lipid droplet plasma membrane lipid transport nervous system development postsynaptic density postsynaptic density membrane integral component of membrane cell junction cytoplasmic vesicle cell death in response to hydrogen peroxide signaling receptor activity identical protein binding cell projection regulation of neuron apoptotic process synapse postsynaptic membrane protein homotrimerization |
|
| TC1100001047.mm.2 |
Cluh |
clustered mitochondria (cluA/CLU1) homolog |
11 |
74649503 |
NM_001081158, BC072573 NM_001081158, BC072573 |
74148 |
19 |
mRNA binding mRNA binding cytoplasm cytoplasm mitochondrion organization intracellular distribution of mitochondria intracellular distribution of mitochondria |
|
| TC0700001689.mm.2 |
Xylt1 |
xylosyltransferase 1 |
7 |
117380978 |
NM_175645, BC157033 NM_175645, BC157033 |
233781 |
18 |
Golgi cis cisterna Golgi membrane extracellular space Golgi apparatus glycosaminoglycan biosynthetic process acetylglucosaminyltransferase activity heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein xylosyltransferase activity protein xylosyltransferase activity protein xylosyltransferase activity proteoglycan biosynthetic process chondroitin sulfate biosynthetic process cellular response to heat ossification involved in bone maturation metal ion binding negative regulation of axon regeneration embryonic skeletal system development chondroitin sulfate proteoglycan biosynthetic process chondroitin sulfate proteoglycan biosynthetic process |
00532 00534 01100 |
| TC0600002858.mm.2 |
Shq1 |
SHQ1 homolog (S. cerevisiae) |
6 |
-100571810 |
NM_181590, BC052657 NM_181590, BC052657 |
72171 |
18 |
box H/ACA snoRNP assembly nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol ribonucleoprotein complex assembly positive regulation of apoptotic process unfolded protein binding negative regulation of rRNA processing |
|
| TC1100004233.mm.2 |
Fasn |
fatty acid synthase |
11 |
-120805957 |
NM_007988, BC046513 NM_007988, BC046513 |
14104 |
153 |
glandular epithelial cell development catalytic activity fatty acid synthase activity fatty acid synthase activity fatty acid synthase activity [acyl-carrier-protein] S-acetyltransferase activity [acyl-carrier-protein] S-malonyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity oleoyl-[acyl-carrier-protein] hydrolase activity cytoplasm mitochondrion Golgi apparatus cytosol plasma membrane acetyl-CoA metabolic process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process fatty acid biosynthetic process metabolic process ether lipid biosynthetic process biosynthetic process tissue development myristoyl-[acyl-carrier-protein] hydrolase activity palmitoyl-[acyl-carrier-protein] hydrolase activity acyl-[acyl-carrier-protein] hydrolase activity oxidoreductase activity transferase activity hydrolase activity hydrolase activity, acting on ester bonds lyase activity 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity neutrophil differentiation monocyte differentiation mammary gland development phosphopantetheine binding glycogen granule identical protein binding enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity cellular response to interleukin-4 establishment of endothelial intestinal barrier 3-oxo-glutaryl-[acp] methyl ester reductase activity 3-oxo-pimeloyl-[acp] methyl ester reductase activity |
00061 01100 04910 |
| TC1100001010.mm.2 |
Atp2a3 |
ATPase, Ca++ transporting, ubiquitous |
11 |
72961168 |
NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 |
53313 |
37 |
nucleotide binding calcium transmembrane transporter activity, phosphorylative mechanism calcium transmembrane transporter activity, phosphorylative mechanism calcium ion binding protein binding ATP binding endoplasmic reticulum endoplasmic reticulum ion transport calcium ion transport cellular calcium ion homeostasis cellular calcium ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process proton-exporting ATPase activity, phosphorylative mechanism cysteine-type endopeptidase activator activity involved in apoptotic process calcium ion transmembrane transporter activity membrane integral component of membrane sarcoplasmic reticulum ATPase activity calcium-dependent ATPase activity organelle membrane endoplasmic reticulum calcium ion homeostasis sarcoplasmic reticulum membrane ion channel binding metal ion binding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress calcium ion transmembrane transport calcium ion transmembrane transport negative regulation of receptor binding calcium ion transport from cytosol to endoplasmic reticulum |
04020 04972 05010 |
| TC0500000785.mm.2 |
Stap1 |
signal transducing adaptor family member 1 |
5 |
86071745 |
NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 |
56792 |
26 |
phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity macrophage colony-stimulating factor receptor binding protein binding nucleus nucleoplasm cytoplasm mitochondrion transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to bacterium positive regulation of gene expression negative regulation of macrophage chemotaxis protein kinase binding protein kinase binding myeloid cell differentiation protein-macromolecule adaptor activity receptor tyrosine kinase binding protein-containing complex signaling adaptor activity signaling adaptor activity negative regulation of phosphorylation intracellular membrane-bounded organelle positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation positive regulation of non-membrane spanning protein tyrosine kinase activity negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity positive regulation of actin cytoskeleton reorganization |
|
| TC0X00001276.mm.2 |
Cenpi |
centromere protein I |
X |
134308083 |
NM_145924, BC030328 NM_145924, BC030328 |
102920 |
14 |
chromosome, centromeric region kinetochore kinetochore molecular_function nucleus chromosome cytosol cytosol biological_process nuclear body nuclear body centromere complex assembly |
|
| TC0800001231.mm.2 |
|
|
|
|
NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 |
|
|
nuclear outer membrane nucleoplasm cytosol protein import into nucleus protein import into nucleus protein import into nucleus protein export from nucleus nucleocytoplasmic transport structural constituent of nuclear pore small GTPase binding nuclear membrane positive regulation of protein import into nucleus identical protein binding nuclear pore central transport channel nuclear pore central transport channel nuclear import signal receptor activity protein localization to nuclear pore nucleocytoplasmic carrier activity negative regulation of vascular endothelial growth factor production |
|
| TC1500002221.mm.2 |
Cers5 |
ceramide synthase 5 |
15 |
-99735591 |
NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797 |
71949 |
46 |
DNA binding endoplasmic reticulum endoplasmic reticulum lipid metabolic process sphingolipid metabolic process membrane integral component of membrane N-acyltransferase activity transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity |
|
| TC0700000225.mm.2 |
Zc3h4 |
zinc finger CCCH-type containing 4 |
7 |
16401195 |
NM_198631, BC057627 NM_198631, BC057627 |
330474 |
35 |
nucleus nucleoplasm cytosol metal ion binding |
|
| TC0200001047.mm.2 |
Pdk1 |
pyruvate dehydrogenase kinase, isoenzyme 1 |
2 |
71873223, 71874903 |
NM_172665, BC027196 NM_172665, BC027196 |
228026 |
52 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrion plasma membrane mitochondrial pyruvate dehydrogenase complex carbohydrate metabolic process glucose metabolic process protein phosphorylation protein phosphorylation cell surface receptor signaling pathway cell population proliferation intrinsic apoptotic signaling pathway in response to oxidative stress regulation of acetyl-CoA biosynthetic process from pyruvate regulation of glucose metabolic process regulation of glucose metabolic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation intracellular signal transduction identical protein binding protein-containing complex binding pyruvate dehydrogenase complex hypoxia-inducible factor-1alpha signaling pathway |
04660 04664 04722 05145 05160 |
| TC1500000420.mm.2 |
Trmt12 |
tRNA methyltransferase 12 |
15 |
58872648 |
NM_026642, BC052533, BC055850 NM_026642, BC052533, BC055850 NM_026642, BC052533, BC055850 |
68260 |
12 |
cytoplasm tRNA processing tRNA methyltransferase activity transferase activity tRNA methylation tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity |
|
| TC1800001632.mm.2 |
Haus1 |
HAUS augmin-like complex, subunit 1 |
18 |
-77757293, -77757293, -77757293 |
NM_146089, BC024400 NM_146089, BC024400 |
225745 |
17 |
molecular_function cytoplasm centrosome cytosol cytosol cytoskeleton microtubule cell cycle centrosome cycle centrosome cycle spindle assembly spindle assembly cell division HAUS complex HAUS complex mitotic spindle microtubule |
|
| TC1600001390.mm.2 |
Rfc4 |
replication factor C (activator 1) 4 |
16 |
-23113947 |
NM_145480, BC003335 NM_145480, BC003335 |
106344 |
29 |
nucleotide binding DNA binding DNA clamp loader activity DNA clamp loader activity ATP binding nucleus nucleoplasm DNA replication factor C complex DNA replication factor C complex DNA replication DNA-dependent DNA replication DNA repair single-stranded DNA helicase activity enzyme binding Ctf18 RFC-like complex Elg1 RFC-like complex positive regulation of DNA-directed DNA polymerase activity |
03030 03420 03430 |
| TC1700001084.mm.2 |
Ddx11 |
DEAD/H box helicase 11 |
17 |
66123519 |
NM_001003919, BC079656 NM_001003919, BC079656 |
320209 |
19 |
nucleotide binding chromatin spindle pole fibrillar center nucleic acid binding DNA binding DNA helicase activity DNA helicase activity chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding RNA binding single-stranded RNA binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytoskeleton nucleobase-containing compound metabolic process DNA replication DNA repair cellular response to DNA damage stimulus sister chromatid cohesion multicellular organism development DNA-dependent ATPase activity RNA-dependent ATPase activity hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides midbody replication fork processing Ctf18 RFC-like complex positive regulation of endodeoxyribonuclease activity negative regulation of protein binding DNA duplex unwinding DNA duplex unwinding establishment of sister chromatid cohesion positive regulation of chromatin binding G-quadruplex DNA unwinding triplex DNA binding positive regulation of sister chromatid cohesion metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding G-quadruplex DNA binding cellular response to hydroxyurea cellular response to cisplatin positive regulation of transcription of nucleolar large rRNA by RNA polymerase I cellular response to bleomycin nucleolar chromatin organization positive regulation of double-strand break repair |
|
| TC1900000099.mm.2 |
Cdca5 |
cell division cycle associated 5 |
19 |
6085096 |
NM_026410, BC052904 NM_026410, BC052904 |
67849 |
34 |
mitotic cell cycle mitotic cell cycle chromatin protein binding nucleus nucleus nucleoplasm chromosome cytoplasm double-strand break repair double-strand break repair cell cycle mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic chromosome condensation mitotic metaphase plate congression mitotic metaphase plate congression positive regulation of exit from mitosis positive regulation of exit from mitosis protein-containing complex binding cell division regulation of cohesin loading regulation of cohesin loading |
|
| TC0300002549.mm.2 |
Phgdh |
3-phosphoglycerate dehydrogenase |
3 |
-98313170 |
NM_016966, BC086668, BC110673 NM_016966, BC086668, BC110673 NM_016966, BC086668, BC110673 |
236539 |
59 |
phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity glutamine metabolic process glycine metabolic process L-serine metabolic process L-serine biosynthetic process threonine metabolic process cellular amino acid biosynthetic process gamma-aminobutyric acid metabolic process regulation of gene expression oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor taurine metabolic process spinal cord development glial cell development neural tube development neurogenesis neuron projection development myelin sheath NAD binding G1 to G0 transition |
00260 01100 |
| TC0700000861.mm.2 |
Dbp |
D site albumin promoter binding protein |
7 |
45705246 |
NM_016974, BC018323 NM_016974, BC018323 |
13170 |
76 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II circadian rhythm positive regulation of transcription by RNA polymerase II rhythmic process sequence-specific double-stranded DNA binding |
|
| TC1900001131.mm.2 |
Ms4a7 |
membrane-spanning 4-domains, subfamily A, member 7 |
19 |
-11321038, -11321038 |
NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402 NM_001025610, NM_001276398, NM_027836, BC024402 |
109225 |
12 |
molecular_function trans-Golgi network biological_process |
|
| TC0200004366.mm.2 |
Arhgap11a |
Rho GTPase activating protein 11A |
2 |
-113831491 |
NM_181416, BC050875 NM_181416, BC050875 |
228482 |
18 |
GTPase activator activity signal transduction |
|
| TC1500001750.mm.2 |
Eef1d |
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
15 |
-75894795, -75894795 |
NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 |
66656 |
35 |
fibrillar center DNA binding translation elongation factor activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytoplasm endoplasmic reticulum cytosol cytosol eukaryotic translation elongation factor 1 complex translation translational elongation mRNA transcription regulation of cell death heat shock protein binding activating transcription factor binding synapse synapse cellular response to ionizing radiation glutamatergic synapse glutamatergic synapse |
|
| TC0600001813.mm.2 |
Slc25a13 |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 |
6 |
-6041217 |
NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571 |
50799 |
49 |
L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity calcium ion binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane ATP biosynthetic process transport L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity aspartate transmembrane transport aspartate transmembrane transport aspartate transmembrane transport L-glutamate transmembrane transport L-glutamate transmembrane transport membrane integral component of membrane transmembrane transporter activity identical protein binding malate-aspartate shuttle malate-aspartate shuttle malate-aspartate shuttle cellular respiration metal ion binding response to calcium ion transmembrane transport |
|
| TC0400001770.mm.2 |
Padi2 |
peptidyl arginine deiminase, type II |
4 |
140906359 |
NM_008812, BC040350, BC049947 NM_008812, BC040350, BC049947 NM_008812, BC040350, BC049947 |
18600 |
50 |
protein-arginine deiminase activity protein-arginine deiminase activity calcium ion binding nucleus cytoplasm cytoplasm regulation of chromatin disassembly hydrolase activity protein citrullination estrogen receptor binding intracellular estrogen receptor signaling pathway transcriptionally active chromatin histone H3-R26 citrullination histone citrullination protein homodimerization activity metal ion binding chromatin-mediated maintenance of transcription negative regulation of chemokine-mediated signaling pathway negative regulation of lymphocyte chemotaxis cellular response to leukemia inhibitory factor |
|
| TC1000002655.mm.2 |
Gas2l3 |
growth arrest-specific 2 like 3 |
10 |
-89408822 |
NM_001033331, NM_001079876, NM_001284344 NM_001033331, NM_001079876, NM_001284344 NM_001033331, NM_001079876, NM_001284344 |
237436 |
22 |
microtubule cytoskeleton organization microtubule cytoskeleton organization actin binding cytoplasm cytoskeleton microtubule actin filament microtubule binding microtubule binding cytoskeletal anchor activity response to bacterium actin cytoskeleton microtubule cytoskeleton actin cytoskeleton organization actin filament binding actin crosslink formation |
|
| TC0800002869.mm.2 |
|
|
|
|
NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654 |
|
|
molecular_function mitochondrion mitochondrion Golgi apparatus intra-Golgi vesicle-mediated transport positive regulation of cell population proliferation protein transport membrane Golgi transport complex Golgi transport complex peptidyl-methionine modification peptidyl-methionine modification N-terminal protein amino acid modification N-terminal protein amino acid modification peptide deformylase activity peptide deformylase activity co-translational protein modification |
|
| TC0700000057.mm.2 |
U2af2 |
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 |
7 |
5062142 |
NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) NM_001205231, NM_133671, BC007487, BC043071, BC106134, U2(U2AF) |
22185 |
42 |
commitment complex mRNA splicing, via spliceosome Prp19 complex nucleic acid binding RNA binding protein binding nucleus spliceosomal complex mRNA processing poly-pyrimidine tract binding RNA splicing nuclear speck nuclear speck nuclear speck enzyme binding pre-mRNA 3'-splice site binding pre-mRNA 3'-splice site binding negative regulation of protein ubiquitination positive regulation of RNA splicing negative regulation of mRNA splicing, via spliceosome C2H2 zinc finger domain binding U2-type prespliceosome U2-type prespliceosome U2AF complex U2AF complex |
03040 |
| TC0700002635.mm.2 |
Ceacam1 |
carcinoembryonic antigen-related cell adhesion molecule 1 |
7 |
-25461701 |
NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926 NM_001039185, NM_001039186, NM_001039187, NM_011926 |
26365 |
145 |
blood vessel development virus receptor activity negative regulation of cytokine production positive regulation of immunoglobulin production negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target actin binding granulocyte colony-stimulating factor receptor binding protein binding calmodulin binding extracellular space plasma membrane plasma membrane cell-cell junction adherens junction negative regulation of protein kinase activity homophilic cell adhesion via plasma membrane adhesion molecules external side of plasma membrane basal plasma membrane cell surface cell surface regulation of endothelial cell migration bile acid transmembrane transporter activity membrane integral component of membrane viral process apical plasma membrane lateral plasma membrane calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules kinase binding protein kinase binding protein phosphatase binding cell junction negative regulation of granulocyte differentiation filamin binding cytoplasmic vesicle brush border membrane negative regulation of interleukin-1 production negative regulation of interleukin-2 production Toll-like receptor binding common myeloid progenitor cell proliferation granulocyte colony-stimulating factor signaling pathway regulation of epidermal growth factor receptor signaling pathway T cell receptor complex positive regulation of T cell proliferation negative regulation of T cell proliferation identical protein binding protein homodimerization activity cell projection negative regulation of vascular permeability positive regulation of MAP kinase activity negative regulation by host of viral process negative regulation by host of viral process positive regulation by host of viral process negative regulation by host of viral genome replication cell-cell junction organization regulation of endothelial cell differentiation negative regulation of osteoclast differentiation negative regulation of bone resorption negative regulation of JNK cascade positive regulation of JNK cascade viral entry into host cell virion binding protein dimerization activity Peyer's patch development negative regulation of lipid biosynthetic process ciliary membrane regulation of blood vessel remodeling positive regulation of activation-induced cell death of T cells positive regulation of calcineurin-NFAT signaling cascade negative regulation of platelet aggregation insulin catabolic process regulation of sprouting angiogenesis protein tyrosine kinase binding protein tyrosine kinase binding negative regulation of hepatocyte proliferation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD8-positive, alpha-beta T cell activation positive regulation of vasculogenesis |
|
| TC0700000904.mm.2 |
Prmt3 |
protein arginine N-methyltransferase 3 |
7 |
49778357 |
NM_133740, BC050775 NM_133740, BC050775 |
71974 |
35 |
protein binding cytoplasm cytosol protein methylation methyltransferase activity protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine negative regulation of protein ubiquitination methylation protein-arginine omega-N asymmetric methyltransferase activity ribosome binding metal ion binding dendritic spine morphogenesis modified amino acid binding |
|
| TC0300003106.mm.2 |
Prkacb |
protein kinase, cAMP dependent, catalytic, beta |
3 |
-146729578, -146729578, -146729578, -146729578 |
NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 |
18749 |
67 |
nucleotide binding magnesium ion binding magnesium ion binding neural tube closure protein kinase activity protein serine/threonine kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity ATP binding ATP binding nucleus nucleus cytoplasm centrosome cytosol cytosol plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex protein phosphorylation protein phosphorylation G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway protein kinase A signaling membrane kinase activity phosphorylation transferase activity ubiquitin protein ligase binding protein kinase A regulatory subunit binding perinuclear region of cytoplasm negative regulation of meiotic cell cycle regulation of protein processing ciliary base negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning |
04010 04020 04062 04114 04210 04270 04310 04340 04540 04720 04740 04742 04910 04912 04914 04916 04962 04970 04971 04976 05020 05146 05414 |
| TC0400001274.mm.2 |
Eif2b3 |
eukaryotic translation initiation factor 2B, subunit 3 |
4 |
117019401, 117019401 |
NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 |
108067 |
22 |
cytoplasmic translational initiation translation initiation factor activity translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm eukaryotic translation initiation factor 2B complex eukaryotic translation initiation factor 2B complex translational initiation translation factor activity, RNA binding response to heat response to glucose oligodendrocyte development guanyl-nucleotide exchange factor complex response to peptide hormone T cell receptor signaling pathway |
03013 |
| TC0700003829.mm.2 |
P2ry6 |
pyrimidinergic receptor P2Y, G-protein coupled, 6 |
7 |
-100937633 |
NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095 |
233571 |
54 |
G protein-coupled ADP receptor activity G protein-coupled receptor activity plasma membrane phagocytosis signal transduction G protein-coupled receptor signaling pathway positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane pyrimidine nucleotide binding transepithelial chloride transport positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor activity G protein-coupled UDP receptor activity G protein-coupled UDP receptor activity G protein-coupled UTP receptor activity positive regulation of ERK1 and ERK2 cascade cellular response to prostaglandin E stimulus cellular response to organic cyclic compound cellular response to purine-containing compound positive regulation of vascular associated smooth muscle cell proliferation cellular response to pyrimidine ribonucleotide |
04080 |
| TC1300001190.mm.2 |
Dimt1 |
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae) |
13 |
106947128 |
NM_025447, BC019799 NM_025447, BC019799 |
66254 |
18 |
rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding nucleus nucleoplasm nucleolus mitochondrial matrix cytosol rRNA processing methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation rRNA methylation methylation 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity positive regulation of rRNA processing |
|
| TC0300001289.mm.2 |
Zgrf1 |
zinc finger, GRF-type containing 1 |
3 |
127553488 |
NM_197997 |
71643 |
15 |
RNA binding cytoplasm zinc ion binding membrane integral component of membrane 5'-flap endonuclease activity metal ion binding replication fork reversal |
|
| TC0300002730.mm.2 |
Ampd2 |
adenosine monophosphate deaminase 2 |
3 |
-108074061, -108074058, -108074061 |
NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119 NM_001289719, NM_001289720, NM_028779, BC049119 |
109674 |
31 |
AMP deaminase activity AMP deaminase activity AMP deaminase activity cytosol cytosol IMP biosynthetic process IMP biosynthetic process IMP biosynthetic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity IMP salvage cholesterol homeostasis identical protein binding AMP metabolic process AMP metabolic process ATP metabolic process ATP metabolic process GTP metabolic process GTP metabolic process metal ion binding cyclic purine nucleotide metabolic process glomerular visceral epithelial cell development energy homeostasis energy homeostasis |
00230 01100 |
| TC1400002600.mm.2 |
Dis3 |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
14 |
-99076633 |
NM_028315, BC027357 NM_028315, BC027357 |
72662 |
27 |
3'-5'-exoribonuclease activity 3'-5'-exoribonuclease activity nuclear exosome (RNase complex) nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) RNA binding nuclease activity endonuclease activity endonuclease activity exonuclease activity ribonuclease activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytosol rRNA processing rRNA catabolic process rRNA catabolic process hydrolase activity CUT catabolic process |
03018 |
| TC0800001436.mm.2 |
6430548M08Rik |
RIKEN cDNA 6430548M08 gene |
8 |
120114151, 120114151, 120144928 |
NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 |
234797 |
15 |
molecular_function cellular_component biological_process |
|
| TC1000000240.mm.2 |
Arhgap18 |
Rho GTPase activating protein 18 |
10 |
26772511 |
NM_176837, BC030858 NM_176837, BC030858 |
73910 |
22 |
ruffle GTPase activator activity GTPase activator activity cytoplasm cytoplasm cytosol cytoplasmic microtubule plasma membrane signal transduction small GTPase mediated signal transduction regulation of cell shape nuclear speck regulation of actin filament polymerization regulation of actin filament polymerization regulation of actin cytoskeleton organization regulation of small GTPase mediated signal transduction regulation of small GTPase mediated signal transduction regulation of cell motility |
|
| TC1100004054.mm.2 |
Cd300c2 |
CD300C molecule 2 |
11 |
-114996768 |
NM_134158, BC006801 NM_134158, BC006801 |
140497 |
21 |
positive regulation of cytokine production immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane plasma membrane membrane integral component of membrane |
|
| TC0700001348.mm.2 |
Alg8 |
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase) |
7 |
97371616 |
NM_199035, BC061244 NM_199035, BC061244 |
381903 |
20 |
alpha-1,3-mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups protein N-linked glycosylation via asparagine dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity |
00510 01100 |
| TC0100003814.mm.2 |
Dtl |
denticleless E3 ubiquitin protein ligase |
1 |
-191537355 |
NM_029766 |
76843 |
33 |
protein polyubiquitination ubiquitin-protein transferase activity nucleus nucleoplasm chromosome nucleolus cytoplasm centrosome cytosol cytoskeleton DNA replication ubiquitin-dependent protein catabolic process protein monoubiquitination cellular response to DNA damage stimulus response to UV positive regulation of G2/M transition of mitotic cell cycle membrane translesion synthesis Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex positive regulation of protein catabolic process rhythmic process regulation of cell cycle signal transduction involved in G2 DNA damage checkpoint Cul4-RING E3 ubiquitin ligase complex |
|
| TC1500001192.mm.2 |
Skp2 |
S-phase kinase-associated protein 2 |
15 |
-9111981, -9111981 |
NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 |
27401 |
133 |
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle protein polyubiquitination protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of intracellular estrogen receptor signaling pathway identical protein binding regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process innate immune response positive regulation of smooth muscle cell proliferation defense response to virus regulation of cell cycle regulation of cell cycle protein K48-linked ubiquitination positive regulation of protein polyubiquitination |
04110 04120 05200 05222 |
| TC1400002215.mm.2 |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
14 |
-63145150, -63145150 |
NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 |
14137 |
44 |
catalytic activity farnesyl-diphosphate farnesyltransferase activity farnesyl-diphosphate farnesyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process ergosterol biosynthetic process metabolic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process lipid biosynthetic process biosynthetic process membrane integral component of membrane sterol biosynthetic process transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups intracellular membrane-bounded organelle farnesyl diphosphate metabolic process farnesyl diphosphate metabolic process metal ion binding squalene synthase activity |
00100 01100 |
| TC1400001785.mm.2 |
Prxl2a |
peroxiredoxin like 2A |
14 |
-40993734, -40993734, -40993734, -40993734, -40993734 |
NM_027464, BC056635 NM_027464, BC056635 |
70564 |
25 |
extracellular region cytoplasm cytoplasm mitochondrion antioxidant activity antioxidant activity regulation of osteoclast differentiation |
|
| TC0700001455.mm.2 |
Rrm1 |
ribonucleotide reductase M1 |
7 |
102441694 |
NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217 |
20133 |
53 |
nucleotide binding catalytic activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding ATP binding nuclear envelope cytoplasm cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity purine nucleotide binding identical protein binding cell projection neuronal cell body protein heterotetramerization ribonucleoside-diphosphate reductase activity disordered domain specific binding |
00230 00240 00480 01100 |
| TC0100000469.mm.2 |
Cyp20a1 |
cytochrome P450, family 20, subfamily a, polypeptide 1 |
1 |
60343299 |
NM_030013, BC049147 NM_030013, BC049147 |
77951 |
17 |
monooxygenase activity iron ion binding membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding metal ion binding |
|
| TC0900001851.mm.2 |
Dnmt1 |
DNA methyltransferase (cytosine-5) 1 |
9 |
-20907205, -20907205, -20907205 |
NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 NM_001199431, NM_001199432, NM_001199433, NM_010066, BC048148, BC053047 |
13433 |
442 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II heterochromatin DNA binding DNA binding chromatin binding RNA binding catalytic activity DNA (cytosine-5-)-methyltransferase activity DNA (cytosine-5-)-methyltransferase activity protein binding nucleus nucleus nucleus nucleoplasm replication fork pericentric heterochromatin cytoplasm DNA methylation DNA methylation chromatin organization Ras protein signal transduction metabolic process methyltransferase activity zinc ion binding methyl-CpG binding DNA-methyltransferase activity DNA-methyltransferase activity maintenance of DNA methylation maintenance of DNA methylation DNA methylation on cytosine within a CG sequence regulation of gene expression positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression gene silencing transferase activity protein domain specific binding estrogen receptor binding methylation DNA methylation on cytosine DNA methylation on cytosine protein-containing complex regulation of cell population proliferation response to drug histone deacetylase binding neuronal cell body DNA methylation involved in embryo development DNA hypermethylation negative regulation of transcription, DNA-templated S-adenosylmethionine metabolic process metal ion binding positive regulation of histone H3-K4 methylation negative regulation of histone H3-K9 methylation DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates cellular response to amino acid stimulus cellular response to transforming growth factor beta stimulus C-5 methylation of cytosine positive regulation of DNA methylation-dependent heterochromatin assembly positive regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching promoter-specific chromatin binding |
00270 01100 |
| TC1100000774.mm.2 |
Tnfrsf13b |
tumor necrosis factor receptor superfamily, member 13b |
11 |
61142483, 61126754 |
NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 NM_021349, BC139392, BC139393, BC141867, BC141868 |
57916 |
81 |
B cell homeostasis B cell homeostasis B cell homeostasis hematopoietic progenitor cell differentiation hematopoietic progenitor cell differentiation adaptive immune response immune system process integral component of plasma membrane external side of plasma membrane membrane integral component of membrane negative regulation of B cell proliferation negative regulation of B cell proliferation |
04060 04672 05340 |
| TC0100000297.mm.2 |
Il1rl2 |
interleukin 1 receptor-like 2 |
1 |
40324588 |
NM_133193, BC117797 NM_133193, BC117797 |
107527 |
33 |
immune system process cytokine receptor activity interleukin-1 receptor activity interleukin-1, type I, activating receptor activity cellular_component inflammatory response signal transduction membrane integral component of membrane hydrolase activity positive regulation of interleukin-6 production innate immune response positive regulation of T cell differentiation NAD(P)+ nucleosidase activity regulation of inflammatory response regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating |
|
| TC0700001736.mm.2 |
Eef2k |
eukaryotic elongation factor-2 kinase |
7 |
120843599, 120851188, 120842830 |
NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 |
13631 |
47 |
nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding calmodulin binding ATP binding translational elongation protein phosphorylation translation factor activity, RNA binding postsynaptic density kinase activity phosphorylation transferase activity regulation of protein autophosphorylation negative regulation of apoptotic process dendritic spine positive regulation of endocytosis protein autophosphorylation positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis |
|
| TC0500001270.mm.2 |
Cit |
citron |
5 |
115845655 |
NM_007708, BC023775, BC051165 NM_007708, BC023775, BC051165 NM_007708, BC023775, BC051165 |
12704 |
52 |
mitotic sister chromatid segregation G2/M transition of mitotic cell cycle nucleotide binding mitotic cell cycle mitotic cytokinesis cytokinesis transcription coactivator binding ruffle protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm vacuole cytosol cytosol cytoskeleton plasma membrane protein phosphorylation Golgi organization cell cycle metaphase/anaphase transition of mitotic cell cycle multicellular organism development spermatogenesis nervous system development regulation of actin polymerization or depolymerization actin cytoskeleton kinase activity phosphorylation dendrite development transferase activity SH3 domain binding peptidyl-threonine phosphorylation protein kinase binding cell differentiation PDZ domain binding protein serine/threonine kinase inhibitor activity midbody actomyosin structure organization Golgi cisterna cleavage furrow positive regulation of cytokinesis negative regulation of hippo signaling intracellular signal transduction neuronal cell body negative regulation of neuron differentiation metal ion binding generation of neurons negative regulation of dendrite morphogenesis cell division neuron apoptotic process scaffold protein binding |
|
| TC1100001051.mm.2 |
Tsr1 |
TSR1 20S rRNA accumulation |
11 |
74898079 |
NM_177325, BC031531 NM_177325, BC031531 |
104662 |
25 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus preribosome, small subunit precursor U3 snoRNA binding ribosome biogenesis |
|
| TC0100001602.mm.2 |
Cd84 |
CD84 antigen |
1 |
171839696, 171839696 |
NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 NM_001252472, NM_001289470, NM_013489, BC140952, BC144736, CD84 |
12523 |
34 |
adaptive immune response immune system process plasma membrane autophagy cell adhesion membrane integral component of membrane regulation of lipopolysaccharide-mediated signaling pathway negative regulation of granulocyte macrophage colony-stimulating factor production negative regulation of interleukin-10 production negative regulation of interleukin-18 production negative regulation of interleukin-6 production positive regulation of tumor necrosis factor production negative regulation of mast cell activation identical protein binding regulation of macrophage activation intracellular membrane-bounded organelle negative regulation of mast cell degranulation positive regulation of MAPK cascade innate immune response positive regulation of NF-kappaB transcription factor activity positive regulation of monocyte chemotactic protein-1 production regulation of store-operated calcium entry |
|
| TC0200005334.mm.2 |
|
|
|
|
NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 |
|
|
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II |
|
| TC1000002686.mm.2 |
Nedd1 |
neural precursor cell expressed, developmentally down-regulated gene 1 |
10 |
-92684744 |
NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870 |
17997 |
34 |
pericentriolar material pericentriolar material spindle pole spindle pole gamma-tubulin ring complex, centrosomal nucleoplasm cytoplasm centrosome centrosome centriole centriole cytoskeleton plasma membrane microtubule depolymerization cell cycle microtubule polymerization or depolymerization ciliary basal body ciliary basal body apical part of cell cell division regulation of establishment of protein localization protein localization to centrosome |
|
| TC0200001675.mm.2 |
Aven |
apoptosis, caspase activation inhibitor |
2 |
112571612, 112492963, 112559681, 112559281, 112618416 |
NM_001165935, NM_028844, BC100725 NM_001165935, NM_028844, BC100725 NM_001165935, NM_028844, BC100725 |
74268 |
21 |
molecular_function apoptotic process negative regulation of G2/M transition of mitotic cell cycle membrane membrane negative regulation of apoptotic process negative regulation of apoptotic process |
|
| TC0100001114.mm.2 |
Mgat5 |
mannoside acetylglucosaminyltransferase 5 |
1 |
127204985 |
NM_145128, BC125533, BC125535 NM_145128, BC125533, BC125535 NM_145128, BC125533, BC125535 |
107895 |
63 |
protein phosphatase inhibitor activity extracellular region Golgi apparatus Golgi apparatus protein N-linked glycosylation protein N-linked glycosylation protein N-linked glycosylation protein N-linked glycosylation acetylglucosaminyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein N-linked glycosylation via asparagine alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity manganese ion binding positive regulation of cell migration negative regulation of protein tyrosine phosphatase activity positive regulation of receptor signaling pathway via STAT |
00510 01100 |
| TC1000002944.mm.2 |
Nup107 |
nucleoporin 107 |
10 |
-117750642 |
NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261 |
103468 |
26 |
chromosome, centromeric region kinetochore posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore chromosome regulation of transcription, DNA-templated mRNA export from nucleus mRNA export from nucleus protein import into nucleus female gonad development protein transport membrane structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring nuclear pore outer ring nuclear membrane nuclear periphery mRNA transport nuclear pore complex assembly nephron development |
03013 |
| TC0700004291.mm.2 |
Sult1a1 |
sulfotransferase family 1A, phenol-preferring, member 1 |
7 |
-126672864 |
NM_133670, BC005413 NM_133670, BC005413 |
20887 |
40 |
nucleotide binding aryl sulfotransferase activity aryl sulfotransferase activity cytoplasm cytosol catecholamine metabolic process lipid metabolic process xenobiotic metabolic process sulfotransferase activity sulfotransferase activity sulfotransferase activity steroid metabolic process estrogen metabolic process transferase activity tyrosine-ester sulfotransferase activity drug metabolic process 4-nitrophenol metabolic process identical protein binding 3'-phosphoadenosine 5'-phosphosulfate binding response to glucocorticoid sulfation sulfation sulfation |
00920 |
| TC1800000794.mm.2 |
Acaa2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) |
18 |
74779211 |
NM_177470, BC028901 NM_177470, BC028901 |
52538 |
34 |
catalytic activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA hydrolase activity acetyl-CoA C-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix acetyl-CoA metabolic process lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation palmitoyl-CoA hydrolase activity transferase activity transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups hydrolase activity acyl-CoA hydrolase activity cellular response to hypoxia myristoyl-CoA hydrolase activity negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway negative regulation of mitochondrial membrane permeability involved in apoptotic process |
00062 00071 00280 01100 |
| TC1400000578.mm.2 |
|
|
|
|
NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 |
|
|
angiogenesis angiogenesis response to hypoxia response to yeast response to yeast positive regulation of endothelial cell proliferation nucleic acid binding DNA binding RNA binding actin binding nuclease activity endonuclease activity ribonuclease activity ribonuclease activity ribonuclease activity signaling receptor binding copper ion binding extracellular region extracellular region extracellular region basement membrane extracellular space extracellular space extracellular space nucleus chromosome nucleolus diacylglycerol biosynthetic process activation of phospholipase C activity multicellular organism development central nervous system development heparin binding cellular response to starvation rRNA transcription response to hormone actin cytoskeleton cell migration hydrolase activity negative regulation of translation antibacterial humoral response antibacterial humoral response antibacterial humoral response antifungal humoral response antifungal humoral response cell differentiation growth cone cytoplasmic vesicle activation of protein kinase B activity angiogenin-PRI complex activation of phospholipase A2 activity peptide binding positive regulation of phosphorylation protein homodimerization activity neuronal cell body innate immune response innate immune response innate immune response negative regulation of smooth muscle cell proliferation positive regulation of protein secretion defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide RNA phosphodiester bond hydrolysis |
|
| TC0700000647.mm.2 |
Pepd |
peptidase D |
7 |
34912406 |
NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 |
18624 |
40 |
aminopeptidase activity peptidase activity peptidase activity metallopeptidase activity hydrolase activity dipeptidase activity manganese ion binding collagen catabolic process metal ion binding proline dipeptidase activity |
|
| TC0600003474.mm.2 |
Sinhcaf |
SIN3-HDAC complex associated factor |
6 |
-148921058, -148921058 |
NM_019643, BC076599 NM_019643, BC076599 |
56306 |
28 |
protein binding nucleus positive regulation of cell population proliferation Sin3 complex Sin3 complex negative regulation of cell migration negative regulation of cell migration negative regulation of cell differentiation |
|
| TC0100003483.mm.2 |
Mgst3 |
microsomal glutathione S-transferase 3 |
1 |
-167371965 |
NM_025569, BC029669 NM_025569, BC029669 |
66447 |
28 |
glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity glutathione peroxidase activity nuclear envelope endoplasmic reticulum lipid metabolic process membrane integral component of membrane oxidoreductase activity transferase activity leukotriene biosynthetic process identical protein binding intracellular membrane-bounded organelle |
00480 00980 00982 |
| TC1200001598.mm.2 |
Dus4l |
dihydrouridine synthase 4-like (S. cerevisiae) |
12 |
-31640054 |
NM_028002, BC109351 NM_028002, BC109351 |
71916 |
15 |
catalytic activity tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity flavin adenine dinucleotide binding |
|
| TC0400002271.mm.2 |
Wwp1 |
WW domain containing E3 ubiquitin protein ligase 1 |
4 |
-19608299 |
NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 |
107568 |
40 |
protein polyubiquitination ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus cytoplasm cytosol plasma membrane ubiquitin-dependent protein catabolic process membrane protein ubiquitination protein ubiquitination protein ubiquitination transferase activity T cell differentiation lung development proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process negative regulation of transcription, DNA-templated ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity |
04120 04144 |
| TC1400001935.mm.2 |
Dlgap5 |
DLG associated protein 5 |
14 |
-47387778 |
NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949 |
218977 |
24 |
nucleus nucleus cytoplasm mitochondrion cytosol cytoskeleton cell cycle mitotic spindle organization chromosome segregation regulation of mitotic cell cycle microtubule binding signaling spindle pole centrosome spindle pole centrosome centriolar satellite kinetochore assembly centrosome localization |
|
| TC0200000651.mm.2 |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
2 |
36230425 |
NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322 |
19224 |
299 |
prostaglandin biosynthetic process prostaglandin biosynthetic process photoreceptor outer segment peroxidase activity prostaglandin-endoperoxide synthase activity nuclear envelope cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process inflammatory response response to oxidative stress learning memory regulation of blood pressure negative regulation of norepinephrine secretion membrane oxidoreductase activity sensory perception of pain cyclooxygenase pathway heme binding keratinocyte differentiation negative regulation of epinephrine secretion maintenance of blood-brain barrier regulation of cell population proliferation intracellular membrane-bounded organelle positive regulation of vasoconstriction positive regulation of smooth muscle contraction metal ion binding dioxygenase activity |
00590 01100 |
| TC0800000114.mm.2 |
F7 |
coagulation factor VII |
8 |
13026033 |
NM_010172, BC061149 NM_010172, BC061149 |
14068 |
48 |
positive regulation of leukocyte chemotaxis positive regulation of leukocyte chemotaxis endopeptidase activity serine-type endopeptidase activity signaling receptor binding calcium ion binding extracellular region extracellular region extracellular space extracellular space proteolysis blood coagulation blood coagulation blood coagulation hemostasis peptidase activity serine-type peptidase activity positive regulation of platelet-derived growth factor receptor signaling pathway protein processing hydrolase activity positive regulation of blood coagulation response to nutrient levels vesicle positive regulation of positive chemotaxis positive regulation of protein kinase B signaling response to anticoagulant response to cholesterol response to astaxanthin serine-type peptidase complex |
04610 |
| TC0400000662.mm.2 |
Snx30 |
sorting nexin family member 30 |
4 |
59805649 |
NM_172468, BC099674 NM_172468, BC099674 |
209131 |
14 |
cytoplasm protein transport phosphatidylinositol binding |
|
| TC1000003220.mm.2 |
Nt5dc3 |
5'-nucleotidase domain containing 3 |
10 |
86779004 |
NM_175331, BC172705 NM_175331, BC172705 |
103466 |
20 |
mitochondrion cytosol 5'-nucleotidase activity hydrolase activity receptor complex metal ion binding |
|
| TC1300000330.mm.2 |
Mboat1 |
membrane bound O-acyltransferase domain containing 1 |
13 |
30136489 |
NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653 |
218121 |
18 |
endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phospholipid biosynthetic process regulation of neuron projection development membrane integral component of membrane transferase activity transferase activity, transferring acyl groups lipid modification phosphatidylserine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoserine O-acyltransferase activity |
00561 00564 01100 |
| TC0900001582.mm.2 |
Exog |
endo/exonuclease (5'-3'), endonuclease G-like |
9 |
119444959 |
NM_001172136, NM_172456, BC119024 NM_001172136, NM_172456, BC119024 NM_001172136, NM_172456, BC119024 |
208194 |
20 |
single-stranded DNA endodeoxyribonuclease activity nucleic acid binding nuclease activity endonuclease activity endonuclease activity endoribonuclease activity nucleus mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane apoptotic DNA fragmentation 5'-3' exonuclease activity 5'-3' exonuclease activity membrane hydrolase activity protein-containing complex metal ion binding |
04210 |
| TC1000000830.mm.2 |
Wdr18 |
WD repeat domain 18 |
10 |
79960151 |
NM_175450, BC095984 NM_175450, BC095984 |
216156 |
29 |
molecular_function nucleus nucleoplasm nuclear pre-replicative complex cytoplasm rRNA processing multicellular organism development regulation of DNA-dependent DNA replication initiation Rix1 complex |
|
| TC1800001437.mm.2 |
Adrb2 |
adrenergic receptor, beta 2 |
18 |
-62177712 |
NM_007420, BC032883 NM_007420, BC032883 |
11555 |
345 |
amyloid-beta binding G-protein alpha-subunit binding regulation of systemic arterial blood pressure by norepinephrine-epinephrine diet induced thermogenesis norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure regulation of sodium ion transport desensitization of G protein-coupled receptor signaling pathway by arrestin diaphragm contraction positive regulation of the force of heart contraction by epinephrine G protein-coupled receptor activity adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity protein binding nucleus nucleus cytoplasm endosome Golgi apparatus plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola receptor-mediated endocytosis regulation of smooth muscle contraction signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase binding positive regulation of cell population proliferation associative learning response to cold positive regulation of protein kinase A signaling positive regulation of protein kinase A signaling positive regulation of sodium ion transport potassium channel regulator activity membrane membrane integral component of membrane apical plasma membrane negative regulation of angiogenesis enzyme binding negative regulation of ossification axon dendrite positive regulation of bone mineralization heat generation B2 bradykinin receptor binding positive regulation of ATPase activity neuronal cell body membrane synaptic transmission, glutamatergic ionotropic glutamate receptor binding negative regulation of urine volume negative regulation of multicellular organism growth wound healing sarcolemma identical protein binding protein homodimerization activity positive regulation of apoptotic process dendritic spine intracellular membrane-bounded organelle receptor complex positive regulation of potassium ion transport positive regulation of MAPK cascade protein-containing complex binding bone resorption positive regulation of heart contraction positive regulation of transcription by RNA polymerase II negative regulation of smooth muscle contraction negative regulation of smooth muscle contraction positive regulation of skeletal muscle tissue growth negative regulation of inflammatory response brown fat cell differentiation norepinephrine binding norepinephrine binding protein phosphatase 2A binding regulation of calcium ion transport regulation of sensory perception of pain excitatory postsynaptic potential positive regulation of mini excitatory postsynaptic potential cellular response to hypoxia adrenergic receptor signaling pathway adenylate cyclase-activating adrenergic receptor signaling pathway positive regulation of protein serine/threonine kinase activity negative regulation of platelet aggregation receptor-receptor interaction blood vessel diameter maintenance glutamatergic synapse positive regulation of cold-induced thermogenesis positive regulation of autophagosome maturation positive regulation of lipophagy cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of calcium ion import across plasma membrane regulation of synaptic vesicle exocytosis positive regulation of AMPA receptor activity |
04020 04080 04144 04970 |
| TC1900001336.mm.2 |
Ak3 |
adenylate kinase 3 |
19 |
-29020831 |
NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 NM_021299, BC016432, BC019174, BC024871, BC058191 |
56248 |
23 |
nucleotide binding adenylate kinase activity adenylate kinase activity ATP binding GTP binding cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial intermembrane space mitochondrial matrix mitochondrial matrix mitochondrial matrix nucleobase-containing compound metabolic process ADP biosynthetic process AMP phosphorylation nucleoside triphosphate biosynthetic process kinase activity phosphorylation transferase activity phosphotransferase activity, phosphate group as acceptor nucleobase-containing compound kinase activity identical protein binding AMP metabolic process AMP metabolic process ATP metabolic process GTP metabolic process ITP metabolic process UTP metabolic process dATP metabolic process nucleoside triphosphate adenylate kinase activity nucleoside triphosphate adenylate kinase activity |
00240 |
| TC1500000742.mm.2 |
Srebf2 |
sterol regulatory element binding factor 2 |
15 |
82147268 |
NM_033218, BC167259 NM_033218, BC167259 |
20788 |
149 |
negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II lipid metabolic process protein C-terminus binding steroid metabolic process cholesterol metabolic process cellular response to starvation response to hormone positive regulation of cholesterol storage positive regulation of cholesterol storage membrane integral component of membrane dendrite cytoplasmic vesicle SREBP signaling pathway SREBP-SCAP-Insig complex cholesterol homeostasis intracellular membrane-bounded organelle sequence-specific DNA binding positive regulation of cholesterol biosynthetic process positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein dimerization activity E-box binding negative regulation of cholesterol efflux positive regulation of pri-miRNA transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC1900001514.mm.2 |
Exosc1 |
exosome component 1 |
19 |
-41922979 |
NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423 |
66583 |
25 |
nuclear exosome (RNase complex) exosome (RNase complex) RNA binding protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing |
03018 |
| TC0100003449.mm.2 |
Mpzl1 |
myelin protein zero-like 1 |
1 |
-165592175, -165592180 |
NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563 |
68481 |
23 |
protein binding integral component of plasma membrane signal transduction membrane integral component of membrane positive regulation of cell migration |
04514 |
| TC0100002838.mm.2 |
Dtymk |
deoxythymidylate kinase |
1 |
-93792575, -93800494 |
NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 |
21915 |
24 |
nucleotide binding nucleoside diphosphate kinase activity thymidylate kinase activity thymidylate kinase activity thymidylate kinase activity ATP binding nucleus cytoplasm mitochondrion mitochondrion mitochondrial intermembrane space mitochondrial matrix cytosol dUDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process dTTP biosynthetic process uridylate kinase activity nucleotide biosynthetic process kinase activity phosphorylation transferase activity cellular response to growth factor stimulus |
00240 01100 |
| TC0800000328.mm.2 |
Plpp5 |
phospholipid phosphatase 5 |
8 |
25720047 |
NM_028000 |
71910 |
16 |
diacylglycerol diphosphate phosphatase activity plasma membrane lipid metabolic process phosphatidate phosphatase activity phosphatidate phosphatase activity membrane integral component of membrane hydrolase activity phospholipid dephosphorylation phospholipid dephosphorylation |
|
| TC0300001046.mm.2 |
Dennd2c |
DENN/MADD domain containing 2C |
3 |
103140325, 103127555, 103102658 |
NM_177857, BC060666 NM_177857, BC060666 |
329727 |
21 |
guanyl-nucleotide exchange factor activity nucleoplasm |
|
| TC1500001181.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0200004598.mm.2 |
Ckap2l |
cytoskeleton associated protein 2-like |
2 |
-129268209 |
NM_181589, BC053443 NM_181589, BC053443 |
70466 |
18 |
molecular_function cytoplasm centrosome centrosome cytosol cytosol cytoskeleton biological_process mitotic spindle mitotic spindle |
|
| TC0800001863.mm.2 |
Ckap2 |
cytoskeleton associated protein 2 |
8 |
-22168151 |
NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023 |
80986 |
26 |
mitotic cytokinesis molecular_function cytoplasm centrosome cytosol cytoskeleton microtubule apoptotic process negative regulation of microtubule depolymerization cell cycle microtubule cytoskeleton microtubule cytoskeleton positive regulation of transcription by RNA polymerase II |
|
| TC0600001401.mm.2 |
Clec4a2 |
C-type lectin domain family 4, member a2 |
6 |
123122689, 123123315 |
NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 NM_001170332, NM_001170333, NM_011999, BC006623, BC075729, BC096565 |
26888 |
24 |
negative regulation of cytokine production adaptive immune response immune system process plasmacytoid dendritic cell antigen processing and presentation calcium ion binding mannose binding plasma membrane membrane integral component of membrane carbohydrate binding carbohydrate binding negative regulation of tumor necrosis factor production CD8-positive, alpha-beta T cell activation antigen processing and presentation of exogenous peptide antigen via MHC class I innate immune response metal ion binding |
|
| TC0200005476.mm.2 |
Nup35 |
nucleoporin 35 |
2 |
80639263, 80638811 |
NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814 |
69482 |
22 |
nucleic acid binding single-stranded DNA binding phospholipid binding nucleus nuclear pore nuclear lamina nucleoplasm plasma membrane regulation of transcription, DNA-templated NLS-bearing protein import into nucleus nuclear pore organization protein transport membrane structural constituent of nuclear pore nuclear membrane identical protein binding nuclear pore central transport channel nuclear pore nuclear basket mRNA transport cellular response to leukemia inhibitory factor |
03013 |
| TC1000002175.mm.2 |
Man1a |
mannosidase 1, alpha |
10 |
-53904784 |
NM_008548, BC015265 NM_008548, BC015265 |
17155 |
30 |
Golgi membrane Golgi membrane catalytic activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus cytosol N-glycan processing metabolic process membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds ubiquitin-dependent ERAD pathway cytoplasmic vesicle protein targeting to ER metal ion binding mannose trimming involved in glycoprotein ERAD pathway |
00510 01100 04141 |
| TC1200002242.mm.2 |
Fbln5 |
fibulin 5 |
12 |
-101746564, -101746564 |
NM_011812, BC006636 NM_011812, BC006636 |
23876 |
75 |
negative regulation of transcription by RNA polymerase II integrin binding calcium ion binding protein binding extracellular region extracellular region extracellular space extracellular space cell adhesion protein C-terminus binding negative regulation of angiogenesis extracellular matrix constituent conferring elasticity extracellular matrix organization positive regulation of osteoblast proliferation protein localization to cell surface protein homodimerization activity positive regulation of transcription by RNA polymerase II secretion elastic fiber assembly elastic fiber assembly elastic fiber assembly collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix elastic fiber intramembranous bone growth regulation of removal of superoxide radicals |
|
| TC1300000838.mm.2 |
Fastkd3 |
FAST kinase domains 3 |
13 |
68582209 |
NM_027123, BC042506, BC060688 NM_027123, BC042506, BC060688 NM_027123, BC042506, BC060688 |
69577 |
14 |
protein kinase activity nucleoplasm mitochondrion mitochondrion mitochondrial cytochrome c oxidase assembly regulation of mitochondrial mRNA stability positive regulation of mitochondrial translation |
|
| TC1300002204.mm.2 |
Ctsl |
cathepsin L |
13 |
-64361889 |
NM_009984, BC068163 NM_009984, BC068163 |
13039 |
210 |
endopeptidase activity aminopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region extracellular space extracellular space nucleus nucleolus cytoplasm lysosome lysosome lysosome vacuole plasma membrane microvillus proteolysis proteolysis thyroid hormone generation immune response cell communication peptidase activity cysteine-type peptidase activity external side of plasma membrane external side of plasma membrane negative regulation of keratinocyte proliferation membrane protein processing protein processing protein autoprocessing hydrolase activity cysteine-type carboxypeptidase activity secretory granule collagen catabolic process kininogen binding hair follicle morphogenesis cytoplasmic vesicle peptide binding histone binding catagen neuron projection perikaryon CD4-positive, alpha-beta T cell lineage commitment protein-containing complex binding apical part of cell decidualization antigen processing and presentation of peptide antigen proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process elastin catabolic process collagen-containing extracellular matrix regulation of actin cytoskeleton reorganization |
04142 04145 04612 05323 |
| TC0700003988.mm.2 |
Rrp8 |
ribosomal RNA processing 8 |
7 |
-105731729, -105731729 |
NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 |
101867 |
23 |
rDNA heterochromatin assembly rDNA heterochromatin assembly nucleus nucleoplasm chromatin silencing complex chromatin silencing complex nucleolus nucleolus cytosol plasma membrane chromatin organization rRNA processing methyltransferase activity transferase activity methylation rDNA heterochromatin rDNA heterochromatin methylated histone binding methylated histone binding cellular response to glucose starvation cellular response to glucose starvation regulation of transcription by glucose regulation of transcription by glucose positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator |
|
| TC0700004665.mm.2 |
Vkorc1 |
vitamin K epoxide reductase complex, subunit 1 |
7 |
-127893062 |
NM_178600, BC031732 NM_178600, BC031732 |
27973 |
34 |
endoplasmic reticulum blood coagulation blood coagulation blood coagulation response to organonitrogen compound response to organic cyclic compound membrane integral component of membrane oxidoreductase activity drug metabolic process peptidyl-glutamic acid carboxylation peptidyl-glutamic acid carboxylation regulation of blood coagulation vitamin K biosynthetic process vitamin K metabolic process vitamin K metabolic process vitamin K metabolic process vitamin K metabolic process intracellular membrane-bounded organelle response to antibiotic vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-insensitive) activity quinone binding positive regulation of coagulation bone development |
|
| TC0800003162.mm.2 |
Nup133 |
nucleoporin 133 |
8 |
-123897122 |
NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845 |
234865 |
23 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome outer kinetochore transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore nuclear pore nuclear pore chromosome mRNA export from nucleus mRNA export from nucleus protein import into nucleus nuclear pore organization protein transport poly(A)+ mRNA export from nucleus structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore neural tube development neurogenesis nuclear pore outer ring nuclear pore outer ring nuclear membrane paraxial mesoderm development mRNA transport somite development nephron development |
03013 |
| TC0600001404.mm.2 |
Clec4d |
C-type lectin domain family 4, member d |
6 |
123262106 |
NM_001163161, NM_010819, BC099471 NM_001163161, NM_010819, BC099471 NM_001163161, NM_010819, BC099471 |
17474 |
34 |
adaptive immune response T cell differentiation involved in immune response immune system process plasma membrane membrane integral component of membrane carbohydrate binding positive regulation of myeloid dendritic cell activation immunoglobulin receptor binding Fc-gamma receptor signaling pathway defense response to bacterium innate immune response metal ion binding |
|
| TC0200002232.mm.2 |
Gins1 |
GINS complex subunit 1 (Psf1 homolog) |
2 |
150909593, 150909593 |
NM_001163476, NM_027014, BC027537 NM_001163476, NM_027014, BC027537 NM_001163476, NM_027014, BC027537 |
69270 |
20 |
GINS complex inner cell mass cell proliferation protein binding nucleus nucleus chromosome cytoplasm cytoplasm DNA replication DNA strand elongation involved in mitotic DNA replication |
|
| TC0X00003301.mm.2 |
Reps2 |
RALBP1 associated Eps domain containing protein 2 |
X |
-162411951, -162411951 |
NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500 |
194590 |
19 |
molecular_function calcium ion binding cytoplasm plasma membrane endocytosis endosomal transport metal ion binding |
|
| TC0200005349.mm.2 |
|
|
|
|
NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC0500001548.mm.2 |
Gtf2ird2 |
GTF2I repeat domain containing 2 |
5 |
134184037 |
NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159 |
114674 |
18 |
DNA binding protein binding nucleus nucleus transition between fast and slow fiber |
|
| TC1800001741.mm.2 |
|
|
|
|
NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 |
|
|
molecular_function calcium ion binding protein binding plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cell-cell junction cell-cell junction cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules biological_process endosome to lysosome transport membrane integral component of membrane calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules growth cone synapse organization lipid tube assembly involved in organelle fusion |
|
| TC0100003027.mm.2 |
Dars |
aspartyl-tRNA synthetase |
1 |
-128412117, -128363706 |
NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638 |
226414 |
31 |
nucleotide binding nucleic acid binding RNA binding aminoacyl-tRNA ligase activity aspartate-tRNA ligase activity aspartate-tRNA ligase activity ATP binding cytoplasm cytosol cytosol translation tRNA aminoacylation for protein translation aspartyl-tRNA aminoacylation aspartyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex synapse |
00970 |
| TC0900001056.mm.2 |
Cd109 |
CD109 antigen |
9 |
78615545 |
NM_153098, BC052443, CD109 NM_153098, BC052443, CD109 NM_153098, BC052443, CD109 |
235505 |
36 |
negative regulation of protein phosphorylation hair follicle development endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular region extracellular space cytosol plasma membrane negative regulation of peptidase activity negative regulation of keratinocyte proliferation membrane peptidase inhibitor activity negative regulation of transforming growth factor beta receptor signaling pathway anchored component of membrane regulation of keratinocyte differentiation transforming growth factor beta binding negative regulation of wound healing osteoclast fusion |
|
| TC1300000763.mm.2 |
|
|
|
|
NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 NR_029530, NR_029531, NR_029575, BC141279, NM_028079, XM_003688907 |
|
|
RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding aminopeptidase activity nucleus nucleolus nucleolus cytoplasm proteolysis cell aging sensory perception of sound peptidase activity metallopeptidase activity zinc ion binding positive regulation of cell population proliferation response to bacterium regulation of gene expression negative regulation of gene expression Wnt signaling pathway hydrolase activity myelination regulation of viral genome replication regulation of viral genome replication positive regulation of angiogenesis metal ion binding long-term synaptic potentiation retina vasculature development in camera-type eye metalloaminopeptidase activity cellular response to lipopolysaccharide cellular response to inorganic substance cellular response to forskolin cellular response to leukemia inhibitory factor regulation of semaphorin-plexin signaling pathway |
|
| TC0800003037.mm.2 |
Gins2 |
GINS complex subunit 2 (Psf2 homolog) |
8 |
-120581265 |
NM_178856, BC082565 NM_178856, BC082565 |
272551 |
19 |
double-strand break repair via break-induced replication GINS complex nucleus chromosome DNA replication |
|
| TC1100003397.mm.2 |
Ccl9 |
chemokine (C-C motif) ligand 9 |
11 |
-83572916 |
NM_011338, BC139318, BC145962 NM_011338, BC139318, BC145962 NM_011338, BC139318, BC145962 |
20308 |
52 |
monocyte chemotaxis cytokine activity extracellular region extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway chemokine activity neutrophil chemotaxis positive regulation of GTPase activity negative regulation of myoblast differentiation CCR chemokine receptor binding lymphocyte chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor |
04060 04062 |
| TC0800002558.mm.2 |
|
|
|
|
NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 NM_001163029, NM_001163030, NM_001163031, NM_011925, NR_106188, BC006676, CD97 |
|
|
transmembrane signaling receptor activity G protein-coupled receptor activity calcium ion binding extracellular region plasma membrane integral component of plasma membrane cell adhesion signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway external side of plasma membrane membrane integral component of membrane positive regulation of synapse assembly |
|
| TC0200000393.mm.2 |
Pnpla7 |
patatin-like phospholipase domain containing 7 |
2 |
24976032 |
NM_146251, BC141365, BC141366 NM_146251, BC141365, BC141366 NM_146251, BC141365, BC141366 |
241274 |
25 |
lysophospholipase activity lysophospholipase activity lysophospholipase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid droplet lipid metabolic process membrane integral component of membrane lipid catabolic process hydrolase activity phosphatidylcholine catabolic process carboxylic ester hydrolase activity |
|
| TC1100001730.mm.2 |
Itgb3 |
integrin beta 3 |
11 |
104607999 |
NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520 |
16416 |
424 |
positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion fibronectin binding fibronectin binding protease binding positive regulation of leukocyte migration protein disulfide isomerase activity protein kinase C binding integrin binding integrin binding integrin binding protein binding nucleus nucleoplasm plasma membrane cell-cell junction focal adhesion focal adhesion focal adhesion cell-substrate junction assembly cell adhesion cell-matrix adhesion cell-matrix adhesion cell-matrix adhesion integrin-mediated signaling pathway regulation of G protein-coupled receptor signaling pathway integrin complex integrin complex external side of plasma membrane cell surface cell surface cell surface positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of macrophage derived foam cell differentiation positive regulation of fibroblast migration positive regulation of fibroblast migration negative regulation of lipid storage smooth muscle cell migration positive regulation of smooth muscle cell migration membrane integral component of membrane apical plasma membrane apical plasma membrane cell migration fibroblast growth factor binding enzyme binding enzyme binding C-X3-C chemokine binding cell junction platelet activation regulation of cell migration positive regulation of cell migration lamellipodium membrane filopodium membrane microvillus membrane cell-substrate adhesion insulin-like growth factor I binding activation of protein kinase activity negative regulation of lipid transport ruffle membrane regulation of protein localization regulation of actin cytoskeleton organization protein-containing complex cell adhesion mediated by integrin cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading integrin alpha9-beta1 complex integrin alphav-beta3 complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-IGF-1-IGF1R complex alphav-beta3 integrin-HMGB1 complex cellular response to platelet-derived growth factor stimulus apolipoprotein A-I-mediated signaling pathway neuregulin binding melanosome identical protein binding cell projection vascular endothelial growth factor receptor 2 binding receptor complex apoptotic cell clearance apoptotic cell clearance synapse postsynaptic membrane positive regulation of osteoclast differentiation positive regulation of angiogenesis positive regulation of bone resorption positive regulation of bone resorption viral entry into host cell platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation cell projection morphogenesis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process cell adhesion molecule binding extracellular matrix binding negative chemotaxis regulation of release of sequestered calcium ion into cytosol regulation of serotonin uptake negative regulation of cell death regulation of protein tyrosine kinase activity fibrinogen binding fibrinogen binding positive regulation of ERK1 and ERK2 cascade platelet aggregation alpha9-beta1 integrin-ADAM8 complex positive regulation of glomerular mesangial cell proliferation glutamatergic synapse glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization integral component of synaptic membrane positive regulation of substrate adhesion-dependent cell spreading positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway regulation of extracellular matrix organization negative regulation of low-density lipoprotein receptor activity positive regulation of T cell migration |
04145 04380 04510 04512 04640 04810 05410 05412 05414 |
| TC0200002395.mm.2 |
Epb41l1 |
erythrocyte membrane protein band 4.1 like 1 |
2 |
156475533, 156420908, 156421090, 156475548 |
NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815 NM_001006664, NM_013510, BC034751, NM_001003815 |
13821 |
50 |
actin binding signaling receptor binding structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane plasma membrane cytoskeletal protein binding postsynaptic density cortical actin cytoskeleton organization actomyosin structure organization protein-containing complex synaptic membrane |
04530 |
| TC0500000850.mm.2 |
Cxcl2 |
chemokine (C-X-C motif) ligand 2 |
5 |
90903898 |
NM_009140, BC119511, BC119512 NM_009140, BC119511, BC119512 NM_009140, BC119511, BC119512 |
20310 |
162 |
response to molecule of bacterial origin cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis killing of cells of other organism CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway neuron death cellular response to lipopolysaccharide |
04060 04062 04621 |
| TC1100001741.mm.2 |
Mettl2 |
methyltransferase like 2 |
11 |
105126424 |
NM_172567, BC089591 NM_172567, BC089591 |
52686 |
23 |
cellular_component tRNA processing methyltransferase activity transferase activity tRNA methylation tRNA methylation methylation tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity |
00340 00350 |
| TC0X00001382.mm.2 |
Prps1 |
phosphoribosyl pyrophosphate synthetase 1 |
X |
140456602 |
NM_021463, BC054772 NM_021463, BC054772 |
19139 |
35 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleobase metabolic process purine nucleotide biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex urate biosynthetic process identical protein binding protein homodimerization activity ADP binding cellular biosynthetic process hypoxanthine biosynthetic process metal ion binding |
00030 00230 01100 |
| TC0500001576.mm.2 |
Tbl2 |
transducin (beta)-like 2 |
5 |
135149685 |
NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185 |
27368 |
25 |
endoplasmic reticulum protein kinase binding endoplasmic reticulum unfolded protein response translation initiation factor binding cellular response to glucose starvation phosphoprotein binding cellular response to hypoxia |
|
| TC1100001882.mm.2 |
Cd300a |
CD300A molecule |
11 |
114890040 |
NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A NM_170758, BC139296, BC139297, CD300A |
217303 |
31 |
phosphatidylserine binding immune system process serotonin secretion by mast cell transmembrane signaling receptor activity protein binding plasma membrane plasma membrane receptor-mediated endocytosis phosphatidylethanolamine binding negative regulation of serotonin secretion membrane integral component of membrane phosphatase binding negative regulation of B cell proliferation positive regulation of phosphoprotein phosphatase activity negative regulation of mast cell activation involved in immune response negative regulation of MyD88-dependent toll-like receptor signaling pathway signaling receptor activity negative regulation of mast cell degranulation negative regulation of mast cell degranulation negative regulation of MAP kinase activity negative regulation of fibroblast proliferation regulation of T cell receptor signaling pathway negative regulation of B cell receptor signaling pathway negative regulation of NK T cell activation negative regulation of phagocytosis, engulfment negative regulation of neutrophil activation negative regulation of eosinophil activation negative regulation of activation of Janus kinase activity negative regulation of eosinophil migration |
|
| TC0700003831.mm.2 |
P2ry2 |
purinergic receptor P2Y, G-protein coupled 2 |
7 |
-100996567, -100996567 |
NM_008773, BC006613 NM_008773, BC006613 |
18442 |
136 |
G protein-coupled receptor activity ATP binding mitochondrion lysosome early endosome plasma membrane signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of neuron projection development positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain negative regulation of ossification A1 adenosine receptor binding positive regulation of prostaglandin secretion positive regulation of chemokine production G protein-coupled purinergic nucleotide receptor activity G protein-coupled UTP receptor activity positive regulation of penile erection positive regulation of mucus secretion blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis |
04080 |
| TC1500000002.mm.2 |
Selenop |
selenoprotein P |
15 |
3270766, 3270976, 3270810 |
NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 |
20363 |
74 |
selenium compound metabolic process selenium compound metabolic process selenium compound metabolic process protein binding extracellular region extracellular region extracellular space brain development locomotory behavior selenium binding selenium binding post-embryonic development sexual reproduction regulation of growth |
|
| TC0800000621.mm.2 |
Hpgd |
hydroxyprostaglandin dehydrogenase 15 (NAD) |
8 |
56294551 |
NM_008278, BC021157 NM_008278, BC021157 |
15446 |
43 |
prostaglandin E receptor activity extracellular space nucleoplasm cytoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy female pregnancy parturition basolateral plasma membrane 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding positive regulation of apoptotic process response to ethanol negative regulation of cell cycle NAD binding NAD+ binding ductus arteriosus closure positive regulation of vascular associated smooth muscle cell proliferation regulation of prostaglandin catabolic process |
|
| TC1100000995.mm.2 |
Mybbp1a |
MYB binding protein (P160) 1a |
11 |
72441326 |
NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889 |
18432 |
63 |
DNA binding transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleolus nucleolus nucleolus cytoplasm regulation of transcription, DNA-templated transcription factor binding zinc ion binding respiratory electron transport chain circadian regulation of gene expression cellular response to glucose starvation ribosome biogenesis NLS-dependent protein nuclear import complex intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding negative regulation of transcription, DNA-templated rhythmic process E-box binding positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of anoikis |
|
| TC1300002036.mm.2 |
Nop16 |
NOP16 nucleolar protein |
13 |
-54584190 |
NM_178605, BC012213 NM_178605, BC012213 |
28126 |
21 |
nucleus nucleoplasm nucleolus nucleolus ribosomal large subunit biogenesis intracellular membrane-bounded organelle |
|
| TC1900000683.mm.2 |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
19 |
46075846 |
NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 |
70769 |
29 |
protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm nucleolus organization Cajal body small nuclear ribonucleoprotein complex |
|
| TC0400000207.mm.2 |
Mms22l |
MMS22-like, DNA repair protein |
4 |
24496450 |
NM_199467, BC137910, BC145028 NM_199467, BC137910, BC145028 NM_199467, BC137910, BC145028 |
212377 |
19 |
double-strand break repair via homologous recombination double-strand break repair via homologous recombination molecular_function nucleus nucleoplasm cytosol DNA repair cellular response to DNA damage stimulus replication fork processing replication fork processing FACT complex MCM complex MCM complex nuclear replication fork nuclear replication fork |
|
| TC1200000132.mm.2 |
E2f6 |
E2F transcription factor 6 |
12 |
16810964 |
NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F |
50496 |
48 |
regulation of transcription involved in G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleoplasm DNA replication factor A complex transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle protein dimerization activity MLL1 complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex |
|
| TC0800001116.mm.2 |
Arl2bp |
ADP-ribosylation factor-like 2 binding protein |
8 |
94667090, 94666599 |
NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 |
107566 |
23 |
transcription coactivator activity protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space centrosome cytoskeleton cilium midbody GTPase regulator activity positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein cell projection maintenance of protein location in nucleus maintenance of protein location in nucleus |
|
| TC1400002259.mm.2 |
Elp3 |
elongator acetyltransferase complex subunit 3 |
14 |
-65530445 |
NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453 NM_001253812, NM_028811, NR_045599, BC057453 |
74195 |
39 |
tRNA binding neuron migration tRNA wobble uridine modification tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation RNA binding catalytic activity nucleus nucleolus cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II nervous system development central nervous system development tRNA processing phosphorylase kinase regulator activity acetyltransferase activity transferase activity transferase activity, transferring acyl groups positive regulation of cell migration elongator holoenzyme complex elongator holoenzyme complex metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding |
|
| TC1100001049.mm.2 |
Mettl16 |
methyltransferase like 16 |
11 |
74770862 |
NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724 |
67493 |
23 |
RNA methylation mRNA (N6-adenosine)-methyltransferase activity mRNA (N6-adenosine)-methyltransferase activity RNA binding nucleus nucleus cytoplasm mRNA catabolic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process methyltransferase activity posttranscriptional regulation of gene expression posttranscriptional regulation of gene expression transferase activity U6 snRNA 3'-end binding methylation RNA stem-loop binding 23S rRNA (adenine(1618)-N(6))-methyltransferase activity mRNA destabilization rRNA base methylation mRNA methylation mRNA methylation U6 snRNA (adenine-(43)-N(6))-methyltransferase activity snRNA (adenine-N6)-methylation negative regulation of 3'-UTR-mediated mRNA stabilization |
|
| TC0500000260.mm.2 |
Insig1 |
insulin induced gene 1 |
5 |
28071411 |
NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499 |
231070 |
37 |
protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lipid metabolic process triglyceride metabolic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process response to sterol depletion oxysterol binding steroid metabolic process cholesterol metabolic process lipid binding negative regulation of steroid biosynthetic process membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process cellular response to insulin stimulus SREBP signaling pathway SREBP signaling pathway SREBP-SCAP-Insig complex SREBP-SCAP-Insig complex cellular response to sterol SREBP-SCAP complex retention in endoplasmic reticulum SREBP-SCAP complex retention in endoplasmic reticulum inner ear morphogenesis middle ear morphogenesis cholesterol homeostasis negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process roof of mouth development cranial suture morphogenesis negative regulation of protein exit from endoplasmic reticulum negative regulation of cargo loading into COPII-coated vesicle |
|
| TC0500000494.mm.2 |
Ncapg |
non-SMC condensin I complex, subunit G |
5 |
45669924 |
NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960 |
54392 |
26 |
condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex molecular_function cytoplasm cytoplasm mitotic chromosome condensation mitotic chromosome condensation |
|
| TC1900000529.mm.2 |
Kif11 |
kinesin family member 11 |
19 |
37376381 |
NM_010615, BC060670 NM_010615, BC060670 |
16551 |
58 |
nucleotide binding spindle pole microtubule motor activity ATP binding nucleus cytoplasm spindle cytosol cytoskeleton microtubule spindle microtubule spindle microtubule microtubule-based movement cell cycle spindle organization mitotic centrosome separation microtubule binding ATP-dependent microtubule motor activity, plus-end-directed protein kinase binding protein-containing complex regulation of mitotic centrosome separation spindle assembly cell division mitotic spindle mitotic spindle assembly mitotic spindle assembly |
|
| TC1400002515.mm.2 |
Diaph3 |
diaphanous related formin 3 |
14 |
-86655356 |
NM_019670, BC028920, BC085191 NM_019670, BC028920, BC085191 NM_019670, BC028920, BC085191 |
56419 |
64 |
actin binding protein binding nucleus nucleus cytoplasm cytoplasm cytoskeleton organization cellular component organization actin cytoskeleton organization actin filament polymerization small GTPase binding |
04810 |
| TC1000002003.mm.2 |
Amd2 |
S-adenosylmethionine decarboxylase 2 |
10 |
-40287464 |
NM_007444 |
100041585 |
17 |
adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity cytosol cytosol polyamine biosynthetic process spermine biosynthetic process spermidine biosynthetic process lyase activity carboxy-lyase activity putrescine binding putrescine binding identical protein binding |
|
| TC1300001641.mm.2 |
Hfe |
homeostatic iron regulator |
13 |
-23702033 |
NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746 |
15216 |
179 |
negative regulation of T cell antigen processing and presentation negative regulation of T cell cytokine production signaling receptor binding extracellular space extracellular space nucleoplasm early endosome plasma membrane ion transport cellular iron ion homeostasis external side of plasma membrane external side of plasma membrane response to iron ion positive regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral component of membrane BMP signaling pathway beta-2-microglobulin binding cytoplasmic vesicle positive regulation of protein binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of iron ion transport regulation of iron ion transport co-receptor binding hormone biosynthetic process apical part of cell basal part of cell positive regulation of receptor-mediated endocytosis perinuclear region of cytoplasm recycling endosome iron ion homeostasis iron ion homeostasis multicellular organismal iron ion homeostasis cellular response to iron ion positive regulation of peptide hormone secretion iron ion import across plasma membrane negative regulation of receptor binding positive regulation of receptor binding negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I positive regulation of ferrous iron binding positive regulation of transferrin receptor binding terminal web transferrin receptor binding transferrin receptor binding transferrin receptor binding response to iron ion starvation HFE-transferrin receptor complex HFE-transferrin receptor complex regulation of protein localization to cell surface negative regulation of ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process negative regulation of signaling receptor activity positive regulation of signaling receptor activity negative regulation of CD8-positive, alpha-beta T cell activation |
|
| TC0200000492.mm.2 |
Ak8 |
adenylate kinase 8 |
2 |
28700160 |
NM_001033874, BC100481, BC109352 NM_001033874, BC100481, BC109352 NM_001033874, BC100481, BC109352 |
68870 |
19 |
nucleotide binding adenylate kinase activity adenylate kinase activity cytidylate kinase activity cytidylate kinase activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding cytoplasm axoneme nucleobase-containing compound metabolic process nucleoside diphosphate phosphorylation nucleoside diphosphate phosphorylation nucleoside triphosphate biosynthetic process nucleoside triphosphate biosynthetic process kinase activity phosphorylation transferase activity nucleobase-containing compound kinase activity ventricular system development sperm flagellum |
|
| TC0300001247.mm.2 |
Bcar3 |
breast cancer anti-estrogen resistance 3 |
3 |
122483568, 122419756 |
NM_013867, BC023930 NM_013867, BC023930 |
29815 |
26 |
phosphotyrosine residue binding lens morphogenesis in camera-type eye guanyl-nucleotide exchange factor activity cytoplasm focal adhesion signal transduction small GTPase mediated signal transduction insulin receptor signaling pathway membrane kinase binding cell junction positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation of DNA replication positive regulation of epidermal growth factor receptor signaling pathway endothelin receptor signaling pathway |
|
| TC1200000334.mm.2 |
Agmo |
alkylglycerol monooxygenase |
12 |
37241638 |
NM_178767, BC148840 NM_178767, BC148840 |
319660 |
14 |
iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process membrane lipid metabolic process lipid biosynthetic process membrane integral component of membrane oxidoreductase activity ether lipid metabolic process glyceryl-ether monooxygenase activity glyceryl-ether monooxygenase activity |
|
| TC0700002980.mm.2 |
Prmt1 |
protein arginine N-methyltransferase 1 |
7 |
-44976754 |
NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 |
15469 |
104 |
in utero embryonic development protein binding nucleus nucleus cytoplasm cytosol protein methylation methyltransferase activity N-methyltransferase activity protein methyltransferase activity protein methyltransferase activity positive regulation of cell population proliferation methyl-CpG binding histone-arginine N-methyltransferase activity membrane protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity [cytochrome c]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation enzyme binding peptidyl-arginine methylation, to asymmetrical-dimethyl arginine peptidyl-arginine methylation, to asymmetrical-dimethyl arginine snoRNP binding neuron projection development methylation protein-containing complex methylosome protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity peptidyl-arginine omega-N-methylation histone methyltransferase activity histone methyltransferase activity identical protein binding histone H4-R3 methylation histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) positive regulation of erythrocyte differentiation regulation of megakaryocyte differentiation negative regulation of megakaryocyte differentiation positive regulation of hemoglobin biosynthetic process mitogen-activated protein kinase p38 binding protein homooligomerization positive regulation of p38MAPK cascade S-adenosyl-L-methionine binding |
|
| TC1700002541.mm.2 |
Fam98a |
family with sequence similarity 98, member A |
17 |
-75537084, -75537085 |
NM_133747, BC004626 NM_133747, BC004626 |
72722 |
26 |
protein binding protein methylation protein methyltransferase activity positive regulation of cell population proliferation positive regulation of gene expression lysosome localization tRNA-splicing ligase complex positive regulation of ruffle assembly |
|
| TC0700002168.mm.2 |
Tmem150b |
transmembrane protein 150B |
7 |
-4716001, -4706831 |
NM_001142792, NM_177887, BC022651 NM_001142792, NM_177887, BC022651 NM_001142792, NM_177887, BC022651 |
330460 |
13 |
molecular_function lysosome endosome plasma membrane integral component of plasma membrane autophagy regulation of autophagy membrane integral component of membrane cytoplasmic vesicle |
|
| TC0400000085.mm.2 |
Ccne2 |
cyclin E2 |
4 |
11191708, 11191350 |
NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 |
12448 |
79 |
regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex telomere maintenance nucleus cytoplasm centrosome DNA replication initiation cell cycle homologous chromosome pairing at meiosis cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding mitotic cell cycle phase transition cell division regulation of cell cycle chromosome organization involved in meiotic cell cycle cyclin E1-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex regulation of cellular protein localization |
04110 04114 04115 05200 05215 05222 |
| TC0300001364.mm.2 |
Cenpe |
centromere protein E |
3 |
135212562 |
NM_173762 |
229841 |
44 |
nucleotide binding mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed chromosome outer kinetochore microtubule motor activity ATP binding nucleus nucleoplasm chromosome cytoplasm kinetochore microtubule cytosol cytoskeleton microtubule microtubule microtubule-based movement cell cycle mitotic spindle organization spindle assembly involved in female meiosis I chromosome segregation mitotic chromosome movement towards spindle pole mitotic metaphase plate congression regulation of mitotic nuclear division mitotic spindle assembly checkpoint multicellular organism development microtubule binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed attachment of spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore microtubule cytoskeleton protein kinase binding regulation of mitotic metaphase/anaphase transition midbody regulation of protein stability kinetochore binding kinetochore binding establishment of protein localization positive regulation of mitotic metaphase/anaphase transition positive regulation of protein kinase activity positive regulation of protein kinase activity regulation of developmental process spindle midzone cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore kinetochore assembly positive regulation of chromosome segregation positive regulation of attachment of spindle microtubules to kinetochore microtubule plus-end directed mitotic chromosome migration lateral attachment of mitotic spindle microtubules to kinetochore mitotic spindle midzone |
|
| TC0200002010.mm.2 |
Cdc25b |
cell division cycle 25B |
2 |
131186947 |
NM_001111075, NM_023117, BC057568 NM_001111075, NM_023117, BC057568 NM_001111075, NM_023117, BC057568 |
12531 |
69 |
G2/M transition of mitotic cell cycle mitotic cell cycle spindle pole oocyte maturation phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm centrosome cytoskeleton protein phosphorylation protein dephosphorylation cell cycle female meiosis I positive regulation of G2/M transition of mitotic cell cycle hydrolase activity protein kinase binding positive regulation of cytokinesis positive regulation of protein kinase activity positive regulation of mitotic cell cycle cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition |
04010 04110 04914 |
| TC0200000591.mm.2 |
Sh2d3c |
SH2 domain containing 3C |
2 |
32721054, 32727688 |
NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203 NM_001252547, NM_013781, NR_045535, BC113203 |
27387 |
25 |
transmembrane receptor protein tyrosine kinase adaptor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm plasma membrane signal transduction small GTPase mediated signal transduction membrane positive regulation of peptidyl-serine phosphorylation cell projection |
|
| TC1700000402.mm.2 |
Pgap6 |
post-glycosylphosphatidylinositol attachment to proteins 6 |
17 |
26113315 |
NM_021793, BC005722 NM_021793, BC005722 |
60455 |
20 |
molecular_function phospholipase A2 activity lysosome plasma membrane integral component of plasma membrane biological_process membrane integral component of membrane hydrolase activity |
|
| TC0100000456.mm.2 |
Nop58 |
NOP58 ribonucleoprotein |
1 |
59685005 |
NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135 |
55989 |
31 |
TFIID-class transcription factor complex binding fibrillar center nucleus nucleoplasm nucleolus sno(s)RNA-containing ribonucleoprotein complex cytosol Cajal body snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis snoRNA localization ATPase binding pre-snoRNP complex |
03008 |
| TC0100001877.mm.2 |
Plxna2 |
plexin A2 |
1 |
194619828 |
NM_008882, BC068155 NM_008882, BC068155 |
18845 |
130 |
somitogenesis semaphorin receptor complex protein binding plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane negative regulation of cell adhesion signal transduction cell surface receptor signaling pathway regulation of cell shape membrane integral component of membrane semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity neural tube development cerebellar granule cell precursor tangential migration regulation of cell migration regulation of cell migration identical protein binding regulation of GTPase activity positive regulation of axonogenesis centrosome localization pharyngeal system development limb bud formation collagen-containing extracellular matrix semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway involved in axon guidance |
04360 |
| TC1800000509.mm.2 |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
18 |
50128200 |
NM_008292, BC022175 NM_008292, BC022175 |
15488 |
55 |
very long-chain fatty acid metabolic process 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity enoyl-CoA hydratase activity enoyl-CoA hydratase activity estradiol 17-beta-dehydrogenase activity protein binding mitochondrion peroxisome peroxisome peroxisome peroxisomal matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation androgen metabolic process estrogen metabolic process oxidoreductase activity long-chain-enoyl-CoA hydratase activity lyase activity isomerase activity 3-hydroxyacyl-CoA dehydratase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity very long-chain fatty-acyl-CoA metabolic process medium-chain fatty-acyl-CoA metabolic process identical protein binding protein homodimerization activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Sertoli cell development |
00120 01100 04146 |
| TC0200001006.mm.2 |
Dhrs9 |
dehydrogenase/reductase (SDR family) member 9 |
2 |
69380461 |
NM_175512, BC118029 NM_175512, BC118029 |
241452 |
16 |
retinoic acid biosynthetic process alcohol dehydrogenase (NAD+) activity retinol dehydrogenase activity endoplasmic reticulum lipid metabolic process steroid metabolic process androgen metabolic process membrane oxidoreductase activity integral component of endoplasmic reticulum membrane progesterone metabolic process 9-cis-retinoic acid biosynthetic process intracellular membrane-bounded organelle androsterone dehydrogenase activity testosterone dehydrogenase (NAD+) activity androstan-3-alpha,17-beta-diol dehydrogenase activity |
00830 01100 |
| TC0200004547.mm.2 |
Ncaph |
non-SMC condensin I complex, subunit H |
2 |
-127103809 |
NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060 |
215387 |
31 |
condensin complex condensin complex condensin complex condensin complex chromatin binding chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation female meiotic nuclear division meiotic chromosome condensation meiotic chromosome condensation chromosome condensation DNA topoisomerase binding meiotic chromosome segregation cell division female meiosis chromosome separation DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity |
|
| TC1500000659.mm.2 |
Nol12 |
nucleolar protein 12 |
15 |
78934932 |
NM_133800, BC013701, BC094424 NM_133800, BC013701, BC094424 NM_133800, BC013701, BC094424 |
97961 |
20 |
single-stranded DNA binding RNA binding RNA binding nucleus nucleolus nucleolus nucleolus rRNA binding identical protein binding |
|
| TC1700001881.mm.2 |
Kifc1 |
kinesin family member C1 |
17 |
-33875665 |
NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328 NM_001195298, BC003753, BC057162, BC100328 |
100502766 |
35 |
microtubule motor activity microtubule motor activity protein binding nucleus nucleus microtubule organizing center kinesin complex kinesin complex microtubule microtubule-based movement microtubule binding ATP-dependent microtubule motor activity, minus-end-directed negative regulation of centrosome duplication ATPase activity endocytic vesicle spindle pole centrosome vesicle transport along microtubule minus-end-directed vesicle transport along microtubule mitotic spindle mitotic spindle mitotic spindle assembly |
|
| TC0300000902.mm.2 |
Ctsk |
cathepsin K |
3 |
95499209 |
NM_007802, BC046320 NM_007802, BC046320 |
13038 |
199 |
fibronectin binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity collagen binding extracellular region extracellular space extracellular space extracellular space nucleoplasm cytoplasm lysosome lysosome lysosome plasma membrane proteolysis thyroid hormone generation thyroid hormone generation immune response peptidase activity cysteine-type peptidase activity external side of plasma membrane membrane hydrolase activity collagen catabolic process collagen catabolic process intracellular membrane-bounded organelle proteoglycan binding bone resorption bone resorption proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process negative regulation of cartilage development |
04142 04380 04620 05323 |
| TC1100002549.mm.2 |
Hmmr |
hyaluronan mediated motility receptor (RHAMM) |
11 |
-40701387 |
NM_013552, BC021427 NM_013552, BC021427 |
15366 |
47 |
hyaluronic acid binding cytoplasm centrosome cytosol microtubule cytoskeleton |
04512 |
| TC0400002110.mm.2 |
Noc2l |
NOC2 like nucleolar associated transcriptional repressor |
4 |
156236014, 156236009 |
NM_021303, BC020013 NM_021303, BC020013 |
57741 |
25 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II p53 binding negative regulation of B cell apoptotic process chromatin binding transcription corepressor activity transcription corepressor activity nucleus nucleus nucleoplasm nucleoplasm chromosome nucleolus nucleolus cytosol apoptotic process Noc1p-Noc2p complex Noc2p-Noc3p complex nucleosome binding nucleosomal histone binding chromatin assembly cellular response to UV negative regulation of histone acetylation negative regulation of histone acetylation negative regulation of histone acetylation ribosomal large subunit biogenesis histone binding histone binding histone binding repressing transcription factor binding repressing transcription factor binding negative regulation of intrinsic apoptotic signaling pathway |
|
| TC1000000752.mm.2 |
Slc19a1 |
solute carrier family 19 (folate transporter), member 1 |
10 |
77033211, 77032738 |
NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263 |
20509 |
60 |
folic acid binding folic acid binding plasma membrane plasma membrane integral component of plasma membrane organic anion transmembrane transporter activity folic acid transmembrane transporter activity folic acid transmembrane transporter activity folate:anion antiporter activity folate:anion antiporter activity antiporter activity methotrexate transmembrane transporter activity methotrexate transmembrane transporter activity organic anion transport folic acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane brush border membrane vitamin transport methotrexate transport methotrexate transport transmembrane transport cyclic-GMP-AMP binding vitamin transmembrane transporter activity folate transmembrane transport folate transmembrane transport folate transmembrane transport folate import across plasma membrane folate import across plasma membrane |
04977 |
| TC0500001798.mm.2 |
Gtf3a |
general transcription factor III A |
5 |
146948656 |
NM_025652, BC032292 NM_025652, BC032292 |
66596 |
24 |
RNA polymerase III general transcription initiation factor activity nucleic acid binding DNA binding DNA binding RNA binding nucleus nucleoplasm 5S rRNA binding ribosome biogenesis ribosomal large subunit biogenesis metal ion binding |
|
| TC0600003074.mm.2 |
Slc2a3 |
solute carrier family 2 (facilitated glucose transporter), member 3 |
6 |
-122727808 |
NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811 |
20527 |
133 |
acrosomal membrane transporter activity glucose transmembrane transporter activity glucose binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane integral component of plasma membrane caveola carbohydrate transport monosaccharide transmembrane transporter activity membrane integral component of membrane galactoside binding kinase binding transmembrane transporter activity synaptic vesicle membrane xylose binding dehydroascorbic acid transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity cell projection D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity transmembrane transport dehydroascorbic acid transport glucose import across plasma membrane glutamatergic synapse integral component of synaptic membrane transport across blood-brain barrier glucose transmembrane transport glucose transmembrane transport glucose transmembrane transport |
|
| TC1800000708.mm.2 |
Psmg2 |
proteasome (prosome, macropain) assembly chaperone 2 |
18 |
67641586 |
NM_134138, BC016606 NM_134138, BC016606 |
107047 |
21 |
nucleus nucleus cytosol mitotic spindle assembly checkpoint negative regulation of apoptotic process proteasome assembly chaperone-mediated protein complex assembly regulation of cell cycle molecular adaptor activity chaperone complex |
|
| TC0700004361.mm.2 |
|
|
|
|
NM_145590, NR_037290, BC017158 NM_145590, NR_037290, BC017158 NM_145590, NR_037290, BC017158 |
|
|
molecular_function biological_process membrane integral component of membrane |
|
| TC1900001217.mm.2 |
Gcnt1 |
glucosaminyl (N-acetyl) transferase 1, core 2 |
19 |
-17326140, -17326140, -17326140 |
NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126 NM_001136484, NM_010265, NM_173442, BC039126 |
14537 |
68 |
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity extracellular space Golgi apparatus trans-Golgi network acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity glycoprotein biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups Golgi cisterna tissue morphogenesis leukocyte tethering or rolling cell adhesion molecule production kidney morphogenesis |
00512 01100 |
| TC0300002357.mm.2 |
Il6ra |
interleukin 6 receptor, alpha |
3 |
-89869323 |
NM_010559 |
16194 |
145 |
cytokine receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity interleukin-6 receptor binding extracellular region extracellular space plasma membrane interleukin-6 receptor complex interleukin-6 receptor complex positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of activation of Janus kinase activity positive regulation of activation of Janus kinase activity vascular endothelial growth factor production membrane integral component of membrane apical plasma membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway enzyme binding cytokine binding interleukin-11 binding interleukin-6 binding interleukin-6 binding interleukin-6 binding endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production neuronal cell body membrane negative regulation of collagen biosynthetic process response to cytokine positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein protein homodimerization activity receptor complex positive regulation of MAPK cascade developmental growth positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway positive regulation of glomerular mesangial cell proliferation T-helper 17 cell lineage commitment |
04060 04630 04640 |
| TC0200003753.mm.2 |
Gpr155 |
G protein-coupled receptor 155 |
2 |
-73341505 |
NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 |
68526 |
13 |
molecular_function cognition |
|
| TC1100003659.mm.2 |
Plxdc1 |
plexin domain containing 1 |
11 |
-97923236 |
NM_001163608, NM_028199, BC114352 NM_001163608, NM_028199, BC114352 NM_001163608, NM_028199, BC114352 |
72324 |
24 |
angiogenesis protein binding cytoplasm plasma membrane plasma membrane bicellular tight junction membrane integral component of membrane cell junction dendrite neuronal cell body receptor complex |
|
| TC0100003783.mm.2 |
Cenpf |
centromere protein F |
1 |
-189640613 |
NM_001081363 |
108000 |
56 |
mitotic cell cycle mitotic cell cycle chromosome, centromeric region chromosome, centromeric region spindle pole spindle pole condensed chromosome outer kinetochore kidney development nucleus nucleus nucleus nucleus nuclear envelope nucleoplasm cytoplasm centrosome spindle axoneme chromosome segregation protein C-terminus binding transcription factor binding regulation of G2/M transition of mitotic cell cycle regulation of G2/M transition of mitotic cell cycle protein transport regulation of striated muscle tissue development nuclear matrix ventricular system development midbody ciliary basal body protein homodimerization activity pronucleus negative regulation of transcription, DNA-templated metaphase plate congression metaphase plate congression dynein complex binding dynein complex binding ciliary transition fiber ciliary transition fiber |
|
| TC0500002232.mm.2 |
Zfyve28 |
zinc finger, FYVE domain containing 28 |
5 |
-34194893 |
NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051 |
231125 |
20 |
cytoplasm endosome cytosol negative regulation of epidermal growth factor-activated receptor activity negative regulation of epidermal growth factor-activated receptor activity membrane early endosome membrane early endosome membrane phosphatidylinositol-3-phosphate binding negative regulation of epidermal growth factor receptor signaling pathway metal ion binding |
|
| TC1100001156.mm.2 |
Aldoc |
aldolase C, fructose-bisphosphate |
11 |
78324197, 78323072 |
NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184 |
11676 |
84 |
catalytic activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity cytoplasm mitochondrion cytosol glycolytic process apoptotic process aging cytoskeletal protein binding lyase activity fructose 1,6-bisphosphate metabolic process fructose 1,6-bisphosphate metabolic process axon identical protein binding protein-containing complex binding postsynaptic cytosol |
00010 00030 00051 01100 |
| TC1500001933.mm.2 |
Polr3h |
polymerase (RNA) III (DNA directed) polypeptide H |
15 |
-81915029 |
NM_030229, BC010793 NM_030229, BC010793 |
78929 |
23 |
immune system process DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex centrosome nucleobase-containing compound metabolic process transcription, DNA-templated transcription by RNA polymerase III transcription initiation from RNA polymerase III promoter intracellular membrane-bounded organelle innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC1500001005.mm.2 |
Troap |
trophinin associated protein |
15 |
99074972 |
NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227 |
78733 |
12 |
molecular_function cellular_component cytoplasm cell adhesion biological_process |
|
| TC1100001849.mm.2 |
Kcnj2 |
potassium inwardly-rectifying channel, subfamily J, member 2 |
11 |
111066163 |
NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842 |
16518 |
120 |
inward rectifier potassium channel activity inward rectifier potassium channel activity voltage-gated ion channel activity protein binding phosphatidylinositol-4,5-bisphosphate binding smooth endoplasmic reticulum rough endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane ion transport potassium ion transport voltage-gated potassium channel complex intercalated disc regulation of skeletal muscle contraction via regulation of action potential magnesium ion transport membrane integral component of membrane T-tubule dendrite intrinsic component of membrane regulation of ion transmembrane transport identical protein binding identical protein binding neuronal cell body dendritic spine protein homotetramerization relaxation of cardiac muscle regulation of membrane repolarization potassium ion transmembrane transport cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction regulation of cardiac muscle cell contraction voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential regulation of heart rate by cardiac conduction relaxation of skeletal muscle positive regulation of potassium ion transmembrane transport potassium ion import across plasma membrane potassium ion import across plasma membrane |
04971 |
| TC0X00002671.mm.2 |
Las1l |
LAS1-like (S. cerevisiae) |
X |
-95935312, -95935320 |
NM_152822, BC141155 NM_152822, BC141155 |
76130 |
25 |
maturation of 5.8S rRNA maturation of LSU-rRNA nucleus cytoplasm rRNA processing preribosome, large subunit precursor MLL1 complex |
|
| TC0800003160.mm.2 |
Ccsap |
centriole, cilia and spindle associated protein |
8 |
-123840843, -123839973, -123839973 |
NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300 |
73420 |
14 |
cytoplasm centrosome centriole centriole spindle spindle cytoskeleton microtubule cilium axoneme axoneme cell cycle multicellular organism development microtubule binding microtubule binding axon axon ciliary transition zone ciliary transition zone ciliary basal body ciliary basal body cell projection cell division mitotic spindle astral microtubule mitotic spindle regulation of mitotic spindle assembly regulation of mitotic spindle assembly mitotic spindle microtubule depolymerization |
|
| TC0100003639.mm.2 |
Adss |
adenylosuccinate synthetase, non muscle |
1 |
-177763177 |
NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417 |
11566 |
23 |
nucleotide binding adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cytoplasm mitochondrion cytosol purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process aspartate metabolic process ligase activity 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding |
00230 00250 01100 |
| TC1100001586.mm.2 |
Cdc6 |
cell division cycle 6 |
11 |
98907800, 98908150 |
NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434 |
23834 |
42 |
nucleotide binding mitotic cell cycle spindle pole chromatin binding DNA replication origin binding ATP binding nucleus nucleus nucleoplasm cytoplasm spindle cytosol DNA replication DNA replication initiation cell cycle kinase binding regulation of mitotic metaphase/anaphase transition positive regulation of cytokinesis mitotic DNA replication checkpoint intercellular bridge positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of fibroblast proliferation spindle midzone cell division positive regulation of chromosome segregation mitotic spindle |
04110 |
| TC0100003279.mm.2 |
Dhx9 |
DEAH (Asp-Glu-Ala-His) box polypeptide 9 |
1 |
-153455757 |
NM_007842 |
13211 |
54 |
nucleotide binding alternative mRNA splicing, via spliceosome RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding regulatory region RNA binding regulatory region RNA binding RNA polymerase II transcription factor binding immune system process nucleic acid binding DNA binding DNA helicase activity DNA replication origin binding double-stranded DNA binding single-stranded DNA binding transcription coregulator activity transcription coactivator activity RNA binding RNA binding RNA helicase activity double-stranded RNA binding single-stranded RNA binding mRNA binding helicase activity protein binding ATP binding intracellular anatomical structure nucleus nucleus nucleoplasm perichromatin fibrils nucleolus nucleolus nucleolus cytoplasm cytoplasm centrosome polysome cytoskeleton DNA-templated transcription, termination regulation of transcription by RNA polymerase II mRNA processing regulation of translation inflammatory response circadian rhythm RNA splicing RNA secondary structure unwinding actin cytoskeleton RISC complex nuclear body hydrolase activity ATPase activity targeting of mRNA for destruction involved in RNA interference gene silencing by RNA chromatin DNA binding DNA duplex unwinding positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interleukin-18 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production protein-containing complex 3'-5' DNA/RNA helicase activity 3'-5' RNA helicase activity cellular response to heat cellular protein-containing complex assembly siRNA binding RNA stem-loop binding cytoplasmic ribonucleoprotein granule DNA-templated viral transcription polysomal ribosome 3'-5' DNA helicase activity 3'-5' DNA helicase activity G-quadruplex DNA unwinding innate immune response positive regulation of innate immune response triplex DNA binding positive regulation of DNA repair positive regulation of DNA replication positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of RNA export from nucleus metal ion binding nucleoside-triphosphate diphosphatase activity positive regulation of fibroblast proliferation rhythmic process positive regulation of viral transcription regulation of mRNA processing regulation of mRNA processing regulation of defense response to virus by host positive regulation of inflammatory response mRNA transport positive regulation of NF-kappaB transcription factor activity positive regulation of response to cytokine stimulus importin-alpha family protein binding RNA polymerase binding pyroptosis RISC-loading complex small RNA loading onto RISC CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex cellular response to tumor necrosis factor cellular response to exogenous dsRNA nuclear stress granule protein localization to cytoplasmic stress granule positive regulation of viral translation RISC complex binding polysome binding positive regulation of polysome binding single-stranded 3'-5' DNA helicase activity sequence-specific mRNA binding promoter-specific chromatin binding ribonucleoprotein complex ribonucleoprotein complex positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity positive regulation of gene silencing by miRNA regulation of cytoplasmic translation positive regulation of cytoplasmic translation |
|
| TC0100000282.mm.2 |
Npas2 |
neuronal PAS domain protein 2 |
1 |
39194271 |
NM_008719, BC109166 NM_008719, BC109166 |
18143 |
63 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus circadian rhythm circadian regulation of gene expression circadian regulation of gene expression response to drug circadian sleep/wake cycle regulation of circadian rhythm locomotor rhythm positive regulation of DNA repair positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding protein dimerization activity rhythmic process response to redox state response to redox state Hsp90 protein binding negative regulation of cell death CLOCK-BMAL transcription complex sequence-specific double-stranded DNA binding positive regulation of behavioral fear response regulation of response to DNA damage stimulus |
04710 |
| TC1900001691.mm.2 |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
19 |
-55067635, -55067635 |
NM_008149, BC019201 NM_008149, BC019201 |
14732 |
58 |
regulation of cytokine production glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane glycerol-3-phosphate metabolic process lipid metabolic process fatty acid metabolic process fatty acid metabolic process acyl-CoA metabolic process triglyceride metabolic process glycerophospholipid metabolic process diacylglycerol biosynthetic process phosphatidic acid biosynthetic process phosphatidylglycerol biosynthetic process O-acyltransferase activity phospholipid biosynthetic process response to glucose positive regulation of triglyceride biosynthetic process response to activity membrane integral component of membrane transferase activity transferase activity, transferring acyl groups triglyceride biosynthetic process triglyceride biosynthetic process mitochondrial membrane mitochondrial membrane interleukin-2 production cellular response to insulin stimulus positive regulation of multicellular organism growth positive regulation of activated T cell proliferation cellular lipid metabolic process defense response to virus fatty acid homeostasis phospholipid homeostasis negative regulation of activation-induced cell death of T cells |
00561 00564 01100 |
| TC1600001770.mm.2 |
St3gal6 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
16 |
-58469741, -58469741 |
NM_018784, BC052338 NM_018784, BC052338 |
54613 |
23 |
Golgi apparatus cellular protein modification process protein glycosylation glycolipid metabolic process sialyltransferase activity sialyltransferase activity oligosaccharide metabolic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups beta-galactoside alpha-2,3-sialyltransferase activity beta-galactoside alpha-2,3-sialyltransferase activity |
00601 01100 |
| TC0100000447.mm.2 |
Cdk15 |
cyclin-dependent kinase 15 |
1 |
59256905 |
NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 |
271697 |
15 |
regulation of transcription involved in G1/S transition of mitotic cell cycle nucleotide binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity cyclin binding metal ion binding |
|
| TC1700001689.mm.2 |
Nme4 |
NME/NM23 nucleoside diphosphate kinase 4 |
17 |
-26091744 |
NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23 |
56520 |
24 |
nucleotide binding nucleoside diphosphate kinase activity ATP binding mitochondrion mitochondrion mitochondrial intermembrane space GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process lipid transport lipid binding nucleotide metabolic process membrane kinase activity phosphorylation transferase activity protein-containing complex binding metal ion binding GTPase binding cardiolipin binding |
00230 00240 01100 |
| TC1700002208.mm.2 |
Bysl |
bystin-like |
17 |
-47599330 |
NM_016859, BC017530 NM_016859, BC017530 |
53414 |
24 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) in utero embryonic development blastocyst formation trophectodermal cell differentiation nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm cytoplasmic microtubule rRNA processing cell population proliferation snoRNA binding preribosome, small subunit precursor ribosome biogenesis cell projection intracellular membrane-bounded organelle apical part of cell perinuclear region of cytoplasm |
|
| MG-1-pos-10341793_st |
|
|
|
|
|
|
|
|
|
| TC0X00002266.mm.2 |
|
|
|
|
NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271 |
|
|
Golgi membrane cytoplasm endosome early endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus plasma membrane plasma membrane cation transport cobalt ion transport copper ion transport iron ion transport cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity magnesium ion transmembrane transporter activity magnesium ion transport membrane integral component of membrane inorganic cation transmembrane transporter activity inorganic cation transmembrane transporter activity integral component of endoplasmic reticulum membrane membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane EMC complex EMC complex |
|
| TC0100000237.mm.2 |
Hs6st1 |
heparan sulfate 6-O-sulfotransferase 1 |
1 |
36068399 |
NM_015818, BC052316 NM_015818, BC052316 |
50785 |
45 |
angiogenesis sulfotransferase activity heparan sulfate proteoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, enzymatic modification heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane integral component of membrane transferase activity heparan sulfate 6-O-sulfotransferase activity heparan sulfate 6-O-sulfotransferase activity lung alveolus development neuron development labyrinthine layer blood vessel development |
00534 |
| TC1100000892.mm.2 |
Aurkb |
aurora kinase B |
11 |
69045636 |
NM_011496, BC003261 NM_011496, BC003261 |
20877 |
114 |
negative regulation of transcription by RNA polymerase II nucleotide binding chromosome, centromeric region kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region negative regulation of B cell apoptotic process protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm spindle cytoskeleton spindle microtubule protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle assembly checkpoint chromocenter kinase activity phosphorylation transferase activity kinase binding midbody midbody spindle pole centrosome negative regulation of protein binding chromosome passenger complex chromosome passenger complex chromosome passenger complex positive regulation of telomere maintenance via telomerase regulation of cytokinesis positive regulation of cytokinesis protein localization to kinetochore cellular response to UV histone serine kinase activity histone serine kinase activity cleavage furrow formation histone H3-S28 phosphorylation metal ion binding spindle midzone mitotic spindle midzone assembly cell division positive regulation of telomerase activity mitotic spindle pole mitotic spindle pole positive regulation of telomere capping positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore mitotic spindle midzone |
|
| TC0X00001634.mm.2 |
Phka2 |
phosphorylase kinase alpha 2 |
X |
160502161, 160502161, 160502161 |
NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 |
110094 |
27 |
catalytic activity calmodulin binding plasma membrane phosphorylase kinase complex phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process protein phosphorylation membrane |
04020 04910 |
| TC0200003865.mm.2 |
Calcrl |
calcitonin receptor-like |
2 |
-84330626 |
NM_018782, BC138537, BC138540 NM_018782, BC138537, BC138540 NM_018782, BC138537, BC138540 |
54598 |
41 |
angiogenesis angiogenesis adrenomedullin receptor activity adrenomedullin receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity transmembrane signaling receptor activity G protein-coupled receptor activity calcitonin receptor activity cytoplasm lysosome endosome endoplasmic reticulum plasma membrane plasma membrane calcium ion transport signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway heart development positive regulation of cell population proliferation G protein-coupled peptide receptor activity protein transport membrane integral component of membrane receptor internalization negative regulation of smooth muscle contraction positive regulation of smooth muscle cell proliferation negative regulation of inflammatory response cellular response to sucrose stimulus adrenomedullin receptor complex CGRP receptor complex calcitonin gene-related peptide receptor signaling pathway adrenomedullin binding adrenomedullin receptor signaling pathway |
04080 04270 |
| TC0900001099.mm.2 |
Sh3bgrl2 |
SH3 domain binding glutamic acid-rich protein like 2 |
9 |
83548337 |
NM_172507, BC038473 NM_172507, BC038473 |
212531 |
17 |
protein binding nucleus nucleoplasm biological_process SH3 domain binding nuclear membrane |
|
| TC0900001345.mm.2 |
Dusp7 |
dual specificity phosphatase 7 |
9 |
106368631 |
NM_153459, BC010207 NM_153459, BC010207 |
235584 |
22 |
inactivation of MAPK activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity cytoplasm cytosol cytosol protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-threonine dephosphorylation negative regulation of MAP kinase activity mitogen-activated protein kinase binding |
04010 |
| TC1400002150.mm.2 |
Ska3 |
spindle and kinetochore associated complex subunit 3 |
14 |
-57806560 |
NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501 |
219114 |
19 |
mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore molecular_function chromosome cytoplasm centrosome cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cell cycle chromosome segregation chromosome segregation regulation of microtubule polymerization or depolymerization cell division mitotic spindle |
|
| TC0200002869.mm.2 |
Mcm10 |
minichromosome maintenance 10 replication initiation factor |
2 |
-4990723, -4990723 |
NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689 NM_027290, BC094576, BC120687, BC120689 |
70024 |
29 |
DNA binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding nucleus nucleoplasm nucleolus DNA replication DNA replication initiation cellular response to DNA damage stimulus cell population proliferation enzyme binding replication fork protection complex identical protein binding metal ion binding |
|
| TC0300000711.mm.2 |
Nes |
nestin |
3 |
87971092 |
NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893 |
18008 |
988 |
protein binding cytoplasm intermediate filament intermediate filament intermediate filament multicellular organism development nervous system development intermediate filament binding positive regulation of intermediate filament depolymerization CCR5 chemokine receptor binding CCR5 chemokine receptor binding negative regulation of neuron apoptotic process cell projection morphogenesis |
|
| TC1000002212.mm.2 |
Mcu |
mitochondrial calcium uniporter |
10 |
-59446983 |
NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257 |
215999 |
80 |
calcium channel activity calcium channel activity protein binding mitochondrion mitochondrion mitochondrial inner membrane ion transport calcium ion transport mitochondrial calcium ion transmembrane transport mitochondrial calcium ion transmembrane transport uniporter activity uniporter activity membrane integral component of membrane calcium-mediated signaling integral component of mitochondrial inner membrane integral component of mitochondrial inner membrane positive regulation of insulin secretion calcium channel complex calcium channel complex calcium import into the mitochondrion calcium import into the mitochondrion glucose homeostasis identical protein binding identical protein binding protein complex oligomerization mitochondrial calcium ion homeostasis mitochondrial calcium ion homeostasis positive regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration calcium ion transmembrane transport positive regulation of neutrophil chemotaxis positive regulation of mitochondrial fission actin filament reorganization uniplex complex uniplex complex |
|
| MG-1-neg-10339860_st |
|
|
|
|
|
|
|
|
|
| TC1600001280.mm.2 |
Sdf2l1 |
stromal cell-derived factor 2-like 1 |
16 |
-17130137 |
NM_022324, BC053425 NM_022324, BC053425 |
64136 |
21 |
dolichyl-phosphate-mannose-protein mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane membrane endoplasmic reticulum chaperone complex response to endoplasmic reticulum stress protein O-linked mannosylation regulation of apoptotic process chaperone cofactor-dependent protein refolding chaperone binding ATPase binding misfolded protein binding cellular response to misfolded protein ER-associated misfolded protein catabolic process chaperone complex |
|
| TC0100002411.mm.2 |
Wdr12 |
WD repeat domain 12 |
1 |
-60076867, -60076867, -60076867 |
NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 |
57750 |
23 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding nucleus nucleoplasm nucleolus rRNA processing Notch signaling pathway preribosome, large subunit precursor preribosome, large subunit precursor ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex |
|
| TC1300002360.mm.2 |
Polr3g |
polymerase (RNA) III (DNA directed) polypeptide G |
13 |
-81673836 |
NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818 |
67486 |
24 |
immune system process chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytoplasm cytosol transcription by RNA polymerase III cell population proliferation cell population proliferation cell population proliferation nuclear body positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC1000001204.mm.2 |
Galnt4 |
polypeptide N-acetylgalactosaminyltransferase 4 |
10 |
99108134 |
NM_015737, BC057882 NM_015737, BC057882 |
14426 |
21 |
polypeptide N-acetylgalactosaminyltransferase activity Golgi apparatus Golgi apparatus membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine protein O-linked glycosylation via threonine manganese ion binding carbohydrate binding metal ion binding perinuclear region of cytoplasm |
00512 01100 |
| TC1000002586.mm.2 |
Appl2 |
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
10 |
-83600033 |
NM_145220, BC048906 NM_145220, BC048906 |
216190 |
34 |
ruffle phosphatidylserine binding diet induced thermogenesis protein binding nucleus cytoplasm cytoplasm endosome plasma membrane plasma membrane protein import into nucleus cell cycle transforming growth factor beta receptor signaling pathway cell population proliferation cold acclimation endosome membrane endosome membrane regulation of fibroblast migration membrane signaling small GTPase binding cytoplasmic vesicle vesicle early phagosome ruffle membrane adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway phosphatidylinositol binding cellular response to hepatocyte growth factor stimulus early phagosome membrane glucose homeostasis identical protein binding protein homodimerization activity cell projection macropinosome protein-containing complex binding regulation of innate immune response negative regulation of fatty acid oxidation negative regulation of glucose import negative regulation of glucose import negative regulation of neurogenesis protein homotetramerization positive regulation of phagocytosis, engulfment positive regulation of cold-induced thermogenesis negative regulation of cytokine production involved in inflammatory response negative regulation of cellular response to insulin stimulus positive regulation of macropinocytosis positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis regulation of G1/S transition of mitotic cell cycle negative regulation of neural precursor cell proliferation |
|
| TC1100000609.mm.2 |
Kif3a |
kinesin family member 3A |
11 |
53567368 |
NM_008443, BC052707 NM_008443, BC052707 |
16568 |
175 |
nucleotide binding in utero embryonic development kidney development heart looping cilium movement microtubule motor activity protein binding ATP binding cytoplasm centrosome centriole centriole cytosol cytoskeleton kinesin complex microtubule spindle microtubule cilium axoneme microtubule-based movement smoothened signaling pathway determination of left/right symmetry heart development microtubule binding microtubule binding anterograde axonal transport epidermis development anterior/posterior pattern specification dorsal/ventral pattern formation centriole-centriole cohesion protein transport microtubule cytoskeleton ATPase activity kinesin II complex kinesin II complex kinesin binding protein phosphatase binding dentate gyrus development dorsal/ventral neural tube patterning dorsal/ventral neural tube patterning neural tube development cell projection organization spectrin binding forebrain development small GTPase binding motile cilium photoreceptor connecting cilium microtubule anchoring at centrosome epidermal stem cell homeostasis cell projection neuron projection neuronal cell body motile cilium assembly protein-containing complex binding positive regulation of receptor-mediated endocytosis positive regulation of epithelial cell proliferation inner ear receptor cell stereocilium organization cilium assembly cilium assembly neural precursor cell proliferation positive regulation of intracellular protein transport ribbon synapse intraciliary transport particle B binding protein localization to cell junction axon cytoplasm positive regulation of axo-dendritic protein transport non-motile cilium assembly positive regulation of establishment or maintenance of cell polarity regulating cell shape |
|
| TC0600001440.mm.2 |
Pianp |
PILR alpha associated neural protein |
6 |
124998609, 124996719, 124998436 |
NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 |
319352 |
18 |
molecular_function biological_process membrane integral component of membrane basolateral plasma membrane regulation of immune response |
|
| TC1500001791.mm.2 |
Arhgap39 |
Rho GTPase activating protein 39 |
15 |
-76723984 |
NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637 |
223666 |
31 |
GTPase activator activity nucleus cytoplasm cytoskeleton signal transduction postsynapse glutamatergic synapse postsynapse organization |
|
| TC1400000179.mm.2 |
Adk |
adenosine kinase |
14 |
21076151, 21052573 |
NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659 |
11534 |
58 |
nucleotide binding adenosine kinase activity adenosine kinase activity adenosine kinase activity ATP binding nucleus nucleus nucleus nucleoplasm cytoplasm cytosol cytosol cytosol plasma membrane purine ribonucleoside salvage dATP biosynthetic process positive regulation of cardiac muscle hypertrophy kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor positive regulation of T cell proliferation type B pancreatic cell proliferation adenosine metabolic process metal ion binding |
00230 01100 |
| TC1200001262.mm.2 |
Adssl1 |
adenylosuccinate synthetase like 1 |
12 |
112620046 |
NM_007421, BC039943 NM_007421, BC039943 |
11565 |
28 |
nucleotide binding GTPase activity adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity protein binding GTP binding cytoplasm cytoplasm cytoplasm purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process aspartate metabolic process purine ribonucleoside monophosphate biosynthetic process membrane ligase activity identical protein binding 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding actin filament binding |
00230 00250 01100 |
| TC0100003709.mm.2 |
Degs1 |
delta(4)-desaturase, sphingolipid 1 |
1 |
-182275963, -182275963 |
NM_007853, BC003751 NM_007853, BC003751 |
13244 |
39 |
mitochondrion endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane oxidoreductase activity sphingolipid biosynthetic process sphingolipid delta-4 desaturase activity sphingolipid delta-4 desaturase activity sphingolipid delta-4 desaturase activity positive regulation of apoptotic process myelin maintenance ceramide biosynthetic process ceramide biosynthetic process retinol isomerase activity retinol isomerase activity |
00600 01100 |
| TC1100000028.mm.2 |
Pes1 |
pescadillo ribosomal biogenesis factor 1 |
11 |
3963974 |
NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142 |
64934 |
35 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed chromosome RNA binding protein binding nucleus nucleoplasm chromosome nucleolus nucleolus cytosol rRNA processing rRNA processing rRNA processing nucleolus organization cell population proliferation preribosome, large subunit precursor protein localization to organelle ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex PeBoW complex |
|
| TC0X00003209.mm.2 |
Kctd12b |
potassium channel tetramerisation domain containing 12b |
X |
-153685153 |
NM_175429, BC064459 NM_175429, BC064459 |
207474 |
12 |
molecular_function regulation of G protein-coupled receptor signaling pathway receptor complex |
|
| TC0600003072.mm.2 |
Gdf3 |
growth differentiation factor 3 |
6 |
-122605402 |
NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565 NM_008108, BC101963, BC101964, BC103565 |
14562 |
46 |
skeletal system development eye development in utero embryonic development in utero embryonic development response to dietary excess cytokine activity protein binding extracellular region extracellular space cytoplasm signal transduction multicellular organism development endoderm development endoderm development mesoderm development mesoderm development growth factor activity regulation of cell fate commitment positive regulation of pathway-restricted SMAD protein phosphorylation protein kinase binding BMP signaling pathway negative regulation of BMP signaling pathway notochord development somite rostral/caudal axis specification positive regulation of fat cell differentiation negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation formation of anatomical boundary SMAD protein signal transduction primitive streak formation |
|
| TC0X00003371.mm.2 |
Msl3 |
MSL complex subunit 3 |
X |
-168651266, -168651266 |
NM_010832, BC010226 NM_010832, BC010226 |
17692 |
22 |
histone acetyltransferase complex DNA binding nucleus chromatin organization chromatin silencing regulation of transcription, DNA-templated histone acetylation histone deacetylation methylated histone binding NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation histone H4-K16 acetylation histone H4-K16 acetylation histone acetyltransferase activity (H4-K16 specific) MSL complex MSL complex |
|
| TC0500003395.mm.2 |
Hip1 |
huntingtin interacting protein 1 |
5 |
-135406518, -135406495 |
NM_146001, BC017516 NM_146001, BC017516 |
215114 |
55 |
actin binding protein binding phospholipid binding nucleus cytoplasm Golgi apparatus endocytosis endocytosis apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process actin filament organization membrane clathrin-coated vesicle clathrin-coated vesicle cell differentiation clathrin binding extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle clathrin light chain binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity regulation of apoptotic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding postsynaptic membrane positive regulation of epidermal growth factor receptor signaling pathway protein heterodimerization activity positive regulation of receptor-mediated endocytosis positive regulation of receptor-mediated endocytosis clathrin coat assembly clathrin coat assembly protein stabilization actin filament binding actin filament binding clathrin-dependent endocytosis phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding apoptotic signaling pathway presynapse presynapse postsynapse extrinsic component of presynaptic membrane extrinsic component of postsynaptic membrane extrinsic component of postsynaptic membrane glutamatergic synapse positive regulation of platelet-derived growth factor receptor-beta signaling pathway |
05016 |
| TC1200002497.mm.2 |
D430020J02Rik |
RIKEN cDNA D430020J02 gene |
12 |
-116401946 |
NR_028421 |
319545 |
10 |
molecular_function cellular_component biological_process |
|
| TC0200002729.mm.2 |
|
|
|
|
NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 |
|
|
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II |
|
| TC0100001844.mm.2 |
Pacc1 |
proton activated chloride channel 1 |
1 |
191325901 |
NM_025864, BC027151 NM_025864, BC027151 |
66950 |
15 |
chloride channel activity plasma membrane integral component of plasma membrane ion transport chloride transport chloride transport membrane integral component of membrane chloride channel complex pH-gated chloride channel activity pH-gated chloride channel activity |
|
| TC1200002413.mm.2 |
Bag5 |
BCL2-associated athanogene 5 |
12 |
-111709489, -111709490 |
NM_027404, BC037642 NM_027404, BC037642 |
70369 |
20 |
adenyl-nucleotide exchange factor activity protein binding nucleus nucleus cytoplasm mitochondrion cytosol cytosol Golgi organization negative regulation of neuron projection development membrane inclusion body inclusion body protein kinase binding heat shock protein binding negative regulation of protein ubiquitination negative regulation of protein ubiquitination negative regulation of protein ubiquitination ubiquitin protein ligase binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process perinuclear region of cytoplasm perinuclear region of cytoplasm protein stabilization protein stabilization chaperone binding chaperone binding chaperone binding negative regulation of ubiquitin-protein transferase activity negative regulation of ubiquitin-protein transferase activity negative regulation of protein refolding negative regulation of protein refolding neuron death neuron death regulation of inclusion body assembly regulation of inclusion body assembly regulation of inclusion body assembly negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
|
| TC1700000070.mm.2 |
Rps6ka2 |
ribosomal protein S6 kinase, polypeptide 2 |
17 |
7170114 |
NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 |
20112 |
56 |
nucleotide binding magnesium ion binding oocyte maturation brain renin-angiotensin system protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity ribosomal protein S6 kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spindle protein phosphorylation heart development negative regulation of cell population proliferation positive regulation of gene expression cardiac muscle cell apoptotic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation intracellular signal transduction positive regulation of apoptotic process negative regulation of cell cycle negative regulation of meiotic nuclear division heart contraction regulation of protein processing regulation of protein processing cellular response to carbohydrate stimulus meiotic spindle |
04010 04114 04150 04720 04722 04914 |
| TC1100004267.mm.2 |
Trim16 |
tripartite motif-containing 16 |
11 |
62820252 |
NM_053169, BC052821 NM_053169, BC052821 |
94092 |
20 |
DNA binding cytoplasm cytoplasm cytosol plasma membrane zinc ion binding PML body transferase activity interleukin-1 binding NACHT domain binding positive regulation of interleukin-1 beta production histone H3 acetylation histone H4 acetylation positive regulation of keratinocyte differentiation positive regulation of transcription, DNA-templated metal ion binding positive regulation of retinoic acid receptor signaling pathway response to growth hormone |
|
| TC1000001686.mm.2 |
Fbxo5 |
F-box protein 5 |
10 |
-5799157 |
NM_025995, BC053434 NM_025995, BC053434 |
67141 |
29 |
oocyte maturation oocyte maturation protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm spindle cytoskeleton regulation of DNA replication cell cycle spindle assembly involved in female meiosis I regulation of mitotic nuclear division regulation of mitotic cell cycle positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex binding vesicle organization protein kinase binding negative regulation of DNA endoreduplication regulation of meiotic nuclear division positive regulation of osteoblast differentiation negative regulation of meiotic nuclear division negative regulation of meiotic nuclear division negative regulation of mitotic metaphase/anaphase transition microtubule polymerization metal ion binding spindle assembly cell division negative regulation of ubiquitin-protein transferase activity positive regulation of meiosis I positive regulation of biomineral tissue development meiotic spindle negative regulation of ubiquitin protein ligase activity positive regulation of mesenchymal stem cell migration ubiquitin ligase inhibitor activity negative regulation of cellular senescence negative regulation of response to DNA damage stimulus |
04114 |
| TC1000001593.mm.2 |
Timeless |
timeless circadian clock 1 |
10 |
128232062, 128238065 |
NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 NM_001136082, NM_001164080, NM_001164081, NM_011589, BC058641, BC082770 |
21853 |
45 |
DNA replication checkpoint negative regulation of transcription by RNA polymerase II chromatin branching involved in ureteric bud morphogenesis kidney development morphogenesis of an epithelium DNA binding protein binding nucleus nucleus nucleoplasm chromosome DNA repair cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle multicellular organism development circadian rhythm embryo development lung development replication fork protection complex site of double-strand break regulation of circadian rhythm regulation of circadian rhythm positive regulation of circadian rhythm identical protein binding replication fork arrest cell cycle phase transition negative regulation of transcription, DNA-templated replication fork protection rhythmic process branching morphogenesis of an epithelial tube cell division cellular response to hydroxyurea cellular response to cisplatin cellular response to bleomycin positive regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair |
|
| TC0100002964.mm.2 |
Dbi |
diazepam binding inhibitor |
1 |
-120113279, -120113279 |
NM_001037999, NM_007830, BC028874 NM_001037999, NM_007830, BC028874 NM_001037999, NM_007830, BC028874 |
13167 |
65 |
fatty-acyl-CoA binding behavioral fear response hair follicle development extracellular space nucleus cytoplasm mitochondrion endoplasmic reticulum Golgi apparatus plasma membrane triglyceride metabolic process learning or memory synaptic vesicle lipid binding glial cell proliferation lateral ventricle development benzodiazepine receptor binding negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic protein-lipid complex long-chain fatty acyl-CoA binding phosphatidylcholine acyl-chain remodeling identical protein binding contractile fiber skin development positive regulation of lipid biosynthetic process positive regulation of release of sequestered calcium ion into cytosol long-term synaptic potentiation perinuclear endoplasmic reticulum negative regulation of protein lipidation positive regulation of CoA-transferase activity positive regulation of phospholipid transport |
03320 |
| TC1500000524.mm.2 |
Ptp4a3 |
protein tyrosine phosphatase 4a3 |
15 |
73723144, 73748025, 73724929, 73724796 |
NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 NM_001166388, NM_001166389, NM_001166390, NM_008975, BC027445, BC066043 |
19245 |
42 |
phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleus cytoplasm cytoplasm endosome plasma membrane regulation of transcription, DNA-templated protein dephosphorylation Notch signaling pathway membrane dephosphorylation hydrolase activity phosphatase activity positive regulation of vascular permeability endothelial cell migration endothelial cell migration endothelial cell migration regulation of vascular endothelial growth factor signaling pathway positive regulation of NIK/NF-kappaB signaling positive regulation of establishment of protein localization cellular response to leukemia inhibitory factor |
|
| TC0700001897.mm.2 |
Wdr11 |
WD repeat domain 11 |
7 |
129591862 |
NM_172255, BC037177 NM_172255, BC037177 |
207425 |
23 |
protein binding nucleus nucleus cytoplasm cytoplasm Golgi apparatus trans-Golgi network cytosol cytoskeleton cilium axoneme intracellular protein transport heart development regulation of smoothened signaling pathway microtubule cytoskeleton cytoplasmic vesicle multicellular organism growth ciliary basal body ciliary basal body cell projection cilium assembly head development vesicle tethering to Golgi |
|
| TC1300002609.mm.2 |
Rnf180 |
ring finger protein 180 |
13 |
-105147493, -105130569 |
NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700 |
71816 |
19 |
protein polyubiquitination protein binding nucleus endoplasmic reticulum membrane integral component of membrane transferase activity adult behavior intrinsic component of endoplasmic reticulum membrane intrinsic component of endoplasmic reticulum membrane positive regulation of protein ubiquitination ubiquitin conjugating enzyme binding ubiquitin conjugating enzyme binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process norepinephrine metabolic process norepinephrine metabolic process serotonin metabolic process serotonin metabolic process metal ion binding regulation of catalytic activity ubiquitin protein ligase activity ubiquitin protein ligase activity organic cyclic compound metabolic process |
|
| TC1600001471.mm.2 |
Xxylt1 |
xyloside xylosyltransferase 1 |
16 |
-30955502 |
NM_198626, BC031419 NM_198626, BC031419 |
268880 |
16 |
magnesium ion binding protein binding endoplasmic reticulum membrane integral component of membrane O-glycan processing O-glycan processing transferase activity transferase activity, transferring glycosyl groups manganese ion binding manganese ion binding integral component of endoplasmic reticulum membrane UDP-xylosyltransferase activity UDP-xylosyltransferase activity metal ion binding |
|
| TC0400000743.mm.2 |
Tlr4 |
toll-like receptor 4 |
4 |
66827550 |
NM_021297, BC029856 NM_021297, BC029856 |
21898 |
2990 |
activation of MAPK activity lipopolysaccharide binding lipopolysaccharide binding microglial cell activation lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity phagocytic cup activation of innate immune response toll-like receptor signaling pathway toll-like receptor signaling pathway B cell proliferation involved in immune response immune system process nitric oxide production involved in inflammatory response regulation of dendritic cell cytokine production MyD88-dependent toll-like receptor signaling pathway innate immune response-activating signal transduction signaling receptor binding protein binding cytoplasm endosome Golgi apparatus plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane leukotriene metabolic process phagocytosis inflammatory response response to oxidative stress signal transduction activation of NF-kappaB-inducing kinase activity I-kappaB phosphorylation I-kappaB phosphorylation response to bacterium external side of plasma membrane cell surface positive regulation of platelet activation positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression positive regulation of keratinocyte proliferation astrocyte development membrane integral component of membrane hydrolase activity positive regulation of B cell proliferation intrinsic component of plasma membrane lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide interferon-gamma production interleukin-1 beta production regulation of tumor necrosis factor production negative regulation of interferon-gamma production negative regulation of interleukin-17 production negative regulation of interleukin-23 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of interferon-gamma production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 4 signaling pathway TRIF-dependent toll-like receptor signaling pathway signaling receptor activity macrophage activation macrophage activation macrophage activation defense response to bacterium identical protein binding cell projection positive regulation of macrophage activation positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling receptor complex receptor complex positive regulation of DNA binding phosphatidylinositol 3-kinase binding innate immune response membrane raft positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol mast cell activation positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of JNK cascade lipopolysaccharide receptor complex protein heterodimerization activity perinuclear region of cytoplasm NAD(P)+ nucleosidase activity positive regulation of lymphocyte proliferation regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium defense response to Gram-negative bacterium detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process regulation of sensory perception of pain intestinal epithelial structure maintenance positive regulation of macrophage cytokine production NAD+ nucleotidase, cyclic ADP-ribose generating negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway response to fatty acid cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to interferon-gamma negative regulation of cold-induced thermogenesis cellular response to oxidised low-density lipoprotein particle stimulus positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly positive regulation of NIK/NF-kappaB signaling positive regulation of oxidative stress-induced neuron death positive regulation of reactive oxygen species biosynthetic process positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of matrix metallopeptidase secretion cellular response to amyloid-beta positive regulation of chemokine (C-X-C motif) ligand 2 production |
04145 04620 05140 05142 05144 05145 05146 05323 |
| TC0100003786.mm.2 |
Smyd2 |
SET and MYND domain containing 2 |
1 |
-189880491 |
NM_026796, BC023119 NM_026796, BC023119 |
226830 |
30 |
negative regulation of transcription by RNA polymerase II RNA polymerase II complex binding p53 binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol chromatin organization methyltransferase activity negative regulation of cell population proliferation protein-lysine N-methyltransferase activity histone methylation transferase activity histone-lysine N-methyltransferase activity peptidyl-lysine monomethylation peptidyl-lysine dimethylation methylation histone lysine methylation regulation of DNA damage response, signal transduction by p53 class mediator metal ion binding histone methyltransferase activity (H3-K36 specific) |
|
| TC1800000583.mm.2 |
Slc12a2 |
solute carrier family 12, member 2 |
18 |
57878677 |
NM_009194 |
20496 |
193 |
transporter activity protein binding cytosol plasma membrane ion transport potassium ion transport sodium ion transport chloride transport cellular sodium ion homeostasis cell volume homeostasis cell volume homeostasis hyperosmotic response gamma-aminobutyric acid signaling pathway sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity ammonium transmembrane transporter activity ammonium transmembrane transporter activity basal plasma membrane T cell chemotaxis T cell chemotaxis potassium ion transmembrane transporter activity symporter activity cation:chloride symporter activity potassium:chloride symporter activity ammonium transport ammonium transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane lateral plasma membrane protein kinase binding cellular potassium ion homeostasis transepithelial chloride transport cellular chloride ion homeostasis cytoplasmic vesicle membrane multicellular organism growth maintenance of blood-brain barrier sodium ion transmembrane transport cellular response to potassium ion cell projection neuron projection neuronal cell body neuronal cell body cell body positive regulation of cell volume metal ion transmembrane transporter activity detection of mechanical stimulus involved in sensory perception of sound chaperone binding Hsp90 protein binding chloride ion homeostasis potassium ion homeostasis sodium ion homeostasis transmembrane transport branching involved in mammary gland duct morphogenesis mammary duct terminal end bud growth negative regulation of vascular wound healing transepithelial ammonium transport cell periphery cell periphery inorganic anion import across plasma membrane inorganic cation import across plasma membrane sodium ion import across plasma membrane regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission chloride transmembrane transport chloride transmembrane transport positive regulation of aspartate secretion regulation of matrix metallopeptidase secretion potassium ion import across plasma membrane potassium ion import across plasma membrane cellular response to chemokine cellular response to chemokine |
04970 04972 |
| MG-1-pos-10343494_st |
|
|
|
|
|
|
|
|
|
| TC0X00000181.mm.2 |
Maoa |
monoamine oxidase A |
X |
16619697 |
NM_173740, BC029100 NM_173740, BC029100 |
17161 |
136 |
protein binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane cytosol catecholamine metabolic process primary amine oxidase activity primary amine oxidase activity positive regulation of signal transduction membrane integral component of membrane oxidoreductase activity neurotransmitter catabolic process dopamine catabolic process serotonin metabolic process phenylethylamine metabolic process flavin adenine dinucleotide binding serotonin binding |
00260 00330 00340 00350 00360 00380 00982 01100 |
| TC1100001095.mm.2 |
Tlcd3a |
TLC domain containing 3A |
11 |
76202091, 76179670, 76179670 |
NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520 |
116972 |
15 |
molecular_function endoplasmic reticulum plasma membrane membrane integral component of membrane lipid homeostasis |
|
| TC1400001032.mm.2 |
Lpar6 |
lysophosphatidic acid receptor 6 |
14 |
73237890 |
NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 NM_175116, BC047931, BC069991, BC145940, BC145942 |
67168 |
28 |
blastocyst hatching G protein-coupled receptor activity plasma membrane integral component of plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway lysophosphatidic acid receptor activity |
04080 |
| TC0900000050.mm.2 |
Mmp8 |
matrix metallopeptidase 8 |
9 |
7558428 |
NM_008611, BC042742 NM_008611, BC042742 |
17394 |
93 |
endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding positive regulation of gene expression negative regulation of gene expression hydrolase activity extracellular matrix organization collagen catabolic process extracellular matrix negative regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of DNA binding positive regulation of MAPK cascade positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of JNK cascade metal ion binding positive regulation of neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of NIK/NF-kappaB signaling positive regulation of reactive oxygen species biosynthetic process positive regulation of microglial cell activation |
|
| TC0100001351.mm.2 |
Ivns1abp |
influenza virus NS1A binding protein |
1 |
151344485, 151344497, 151344497 |
NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 |
117198 |
29 |
protein binding nucleus cytoplasm cytosol cytoskeleton RNA splicing response to virus negative regulation of protein ubiquitination negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0200000319.mm.2 |
Etl4 |
enhancer trap locus 4 |
2 |
20519512, 20289912, 20510046 |
NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 |
208618 |
46 |
protein binding cytoplasm cytoplasm multicellular organism development enzyme regulator activity embryonic skeletal system development |
|
| TC0800002339.mm.2 |
Psd3 |
pleckstrin and Sec7 domain containing 3 |
8 |
-67689081, -67689081, -67689081 |
NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698 |
234353 |
22 |
guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse |
04144 |
| TC1900000399.mm.2 |
Dock8 |
dedicator of cytokinesis 8 |
19 |
24999528 |
NM_028785, BC141358 NM_028785, BC141358 |
76088 |
43 |
immunological synapse formation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm plasma membrane small GTPase mediated signal transduction membrane cell leading edge leading edge membrane dendritic cell migration dendritic cell migration cell projection positive regulation of GTPase activity memory T cell proliferation negative regulation of T cell apoptotic process positive regulation of establishment of T cell polarity positive regulation of establishment of T cell polarity cellular response to chemokine positive regulation of T cell migration positive regulation of T cell migration |
|
| TC0800003176.mm.2 |
2810004N23Rik |
RIKEN cDNA 2810004N23 gene |
8 |
-124839354 |
NM_025615, BC023675 NM_025615, BC023675 |
66523 |
19 |
chromosome biological_process |
|
| TC1000001020.mm.2 |
Tcp11l2 |
t-complex 11 (mouse) like 2 |
10 |
84576946 |
NM_146008, BC029663 NM_146008, BC029663 |
216198 |
14 |
molecular_function cellular_component signal transduction |
|
| TC1300000967.mm.2 |
Mblac2 |
metallo-beta-lactamase domain containing 2 |
13 |
81711416 |
NM_028372, BC160254 NM_028372, BC160254 |
72852 |
12 |
biological_process hydrolase activity metal ion binding |
|
| TC1500001596.mm.2 |
Washc5 |
WASH complex subunit 5 |
15 |
-59331996 |
NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035 NM_153548, BC034070, BC040815, BC067035 |
223593 |
31 |
oocyte maturation nucleoplasm cytoplasm endosome endosome endosome early endosome endoplasmic reticulum exocytosis phagocytosis endosome organization lysosome organization lysosome organization positive regulation of neuron projection development protein transport endosomal transport actin filament polymerization cellular protein-containing complex localization polar body extrusion after meiotic divisions cholesterol homeostasis identical protein binding neuron projection neuronal cell body protein-containing complex subunit organization protein-containing complex subunit organization regulation of actin nucleation regulation of actin nucleation WASH complex WASH complex WASH complex spindle assembly involved in meiosis regulation of vesicle size endosome fission endosome fission |
|
| TC0400000519.mm.2 |
Tgfbr1 |
transforming growth factor, beta receptor I |
4 |
47353221, 47386215 |
NM_009370, BC063260 NM_009370, BC063260 |
21812 |
328 |
nucleotide binding activation of MAPKK activity skeletal system development angiogenesis in utero embryonic development kidney development blastocyst development epithelial to mesenchymal transition negative regulation of endothelial cell proliferation lens development in camera-type eye ventricular trabecula myocardium morphogenesis ventricular compact myocardium morphogenesis protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta-activated receptor activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type I transforming growth factor beta receptor activity, type I signaling receptor binding type II transforming growth factor beta receptor binding protein binding ATP binding nucleus endosome endosome plasma membrane plasma membrane caveola bicellular tight junction regulation of transcription, DNA-templated protein phosphorylation protein phosphorylation apoptotic process signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway nervous system development heart development heart development positive regulation of cell population proliferation germ cell migration male gonad development embryo development post-embryonic development anterior/posterior pattern specification cell surface regulation of gene expression positive regulation of gene expression positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral component of membrane kinase activity phosphorylation basolateral plasma membrane apical plasma membrane activin receptor activity, type I transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation growth factor binding cell junction cell differentiation collagen fibril organization positive regulation of cell growth positive regulation of cell migration regulation of protein ubiquitination ubiquitin protein ligase binding negative regulation of chondrocyte differentiation activin receptor signaling pathway protein-containing complex regulation of growth positive regulation of apoptotic process negative regulation of apoptotic process receptor complex receptor complex regulation of protein binding endothelial cell migration response to estrogen protein-containing complex binding membrane raft negative regulation of endothelial cell differentiation positive regulation of transcription, DNA-templated SMAD binding SMAD binding SMAD binding protein autophosphorylation metal ion binding activin receptor complex activin binding thymus development neuron fate commitment embryonic cranial skeleton morphogenesis skeletal system morphogenesis artery morphogenesis cell motility transforming growth factor beta binding transforming growth factor beta binding positive regulation of cellular component movement positive regulation of filopodium assembly positive regulation of stress fiber assembly positive regulation of protein kinase B signaling parathyroid gland development roof of mouth development roof of mouth development pharyngeal system development regulation of cardiac muscle cell proliferation pathway-restricted SMAD protein phosphorylation positive regulation of SMAD protein signal transduction ventricular septum morphogenesis angiogenesis involved in coronary vascular morphogenesis coronary artery morphogenesis I-SMAD binding response to cholesterol response to cholesterol cellular response to growth factor stimulus cellular response to transforming growth factor beta stimulus cellular response to transforming growth factor beta stimulus negative regulation of pri-miRNA transcription by RNA polymerase II positive regulation of pri-miRNA transcription by RNA polymerase II positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation positive regulation of tight junction disassembly epicardium morphogenesis positive regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway |
04010 04060 04144 04350 04380 04520 05142 05200 05210 05212 05220 |
| TC0100001836.mm.2 |
Nsl1 |
NSL1, MIS12 kinetochore complex component |
1 |
191063020 |
NM_198654, BC029086 NM_198654, BC029086 |
381318 |
14 |
mitotic sister chromatid segregation MIS12/MIND type complex MIS12/MIND type complex chromosome, centromeric region kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cell cycle chromosome segregation nuclear speck cell division |
|
| TC1000001074.mm.2 |
Nup37 |
nucleoporin 37 |
10 |
88146991, 88147070 |
NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180 NM_027191, NM_028334, BC011102, BC032180 |
69736 |
19 |
chromosome, centromeric region kinetochore molecular_function nucleus nuclear pore nucleoplasm chromosome cell cycle chromosome segregation protein transport nuclear pore outer ring nuclear pore outer ring mRNA transport cell division |
03013 |
| TC1600001254.mm.2 |
Mcm4 |
minichromosome maintenance complex component 4 |
16 |
-15623896 |
NM_008565, BC013094 NM_008565, BC013094 |
17217 |
66 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex mitotic DNA replication initiation |
03030 04110 |
| TC1600000530.mm.2 |
Polq |
polymerase (DNA directed), theta |
16 |
37011785 |
NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 |
77782 |
34 |
nucleotide binding nucleic acid binding DNA binding chromatin binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity ATP binding nucleus nucleoplasm chromosome cytoplasm Golgi apparatus cytosol DNA replication DNA-dependent DNA replication DNA repair DNA repair base-excision repair double-strand break repair cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes transferase activity nucleotidyltransferase activity single-stranded DNA helicase activity identical protein binding protein homooligomerization 5'-deoxyribose-5-phosphate lyase activity double-strand break repair via alternative nonhomologous end joining double-strand break repair via alternative nonhomologous end joining negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC0900000255.mm.2 |
Ncapd3 |
non-SMC condensin II complex, subunit D3 |
9 |
27030164, 27060415 |
NM_178113, BC048190 NM_178113, BC048190 |
78658 |
20 |
condensed chromosome kinetochore condensed chromosome, centromeric region condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm pericentric heterochromatin cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation methylated histone binding histone binding germinal vesicle cell division meiotic chromosome separation |
|
| TC0100003531.mm.2 |
Pcp4l1 |
Purkinje cell protein 4-like 1 |
1 |
-171173263 |
NM_025557 |
66425 |
17 |
molecular_function cellular_component biological_process |
|
| TC0300001076.mm.2 |
Slc16a1 |
solute carrier family 16 (monocarboxylic acid transporters), member 1 |
3 |
104638663 |
NM_009196, BC014777 NM_009196, BC014777 |
20501 |
88 |
mitochondrion centrosome plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane lipid metabolic process centrosome cycle monocarboxylic acid transmembrane transporter activity monocarboxylic acid transmembrane transporter activity basal plasma membrane lactate transmembrane transporter activity symporter activity monocarboxylic acid transport monocarboxylic acid transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane cell junction response to food lactate transmembrane transport plasma membrane lactate transport plasma membrane lactate transport glucose homeostasis identical protein binding intracellular membrane-bounded organelle synapse synapse carboxylic acid transmembrane transporter activity regulation of insulin secretion behavioral response to nutrient transmembrane transport cellular response to organic cyclic compound organic cyclic compound binding carboxylic acid transmembrane transport |
|
| TC1100002813.mm.2 |
Gemin5 |
gem nuclear organelle associated protein 5 |
11 |
-58120000, -58120000 |
NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 |
216766 |
23 |
RNA 7-methylguanosine cap binding spliceosomal snRNP assembly RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleoplasm cytoplasm cytosol mRNA processing translation regulation of translation RNA splicing nuclear body snRNA binding U1 snRNA binding U4 snRNA binding U4atac snRNA binding SMN complex SMN-Gemin2 complex SMN-Sm protein complex ribosome binding |
03013 |
| TC0900002115.mm.2 |
Sc5d |
sterol-C5-desaturase |
9 |
-42254176 |
NM_172769, BC024132 NM_172769, BC024132 |
235293 |
30 |
C-5 sterol desaturase activity C-5 sterol desaturase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process steroid metabolic process lipid biosynthetic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity cholesterol biosynthetic process via lathosterol cholesterol biosynthetic process via lathosterol intracellular membrane-bounded organelle |
00100 01100 |
| TC0900003342.mm.2 |
Syncrip |
synaptotagmin binding, cytoplasmic RNA interacting protein |
9 |
-88449363, -88455581 |
NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 |
56403 |
66 |
nucleic acid binding RNA binding mRNA binding nucleus spliceosomal complex cytoplasm endoplasmic reticulum mRNA processing poly(A) binding RNA splicing negative regulation of translation intracellular membrane-bounded organelle mRNA 5'-UTR binding CRD-mediated mRNA stabilization CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex CRD-mediated mRNA stability complex catalytic step 2 spliceosome histone pre-mRNA 3'end processing complex cellular response to interferon-gamma GAIT complex ribonucleoprotein complex ribonucleoprotein complex |
|
| TC0500002508.mm.2 |
Apbb2 |
amyloid beta (A4) precursor protein-binding, family B, member 2 |
5 |
-66298724, -66298724 |
NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 NM_001201413, NM_001201414, NM_001201415, NM_001201416, NM_009686, BC076587 |
11787 |
36 |
amyloid-beta binding neuron migration protein binding nucleus nucleus cytoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated cell cycle arrest axon guidance transcription factor binding transcription factor binding actin filament-based movement extracellular matrix organization negative regulation of cell growth histone acetyltransferase binding positive regulation of apoptotic process negative regulation of apoptotic process protein stabilization |
|
| MG-1-neg-10339217_st |
|
|
|
|
|
|
|
|
|
| TC0900003248.mm.2 |
Cx3cr1 |
chemokine (C-X3-C motif) receptor 1 |
9 |
-120048682 |
NM_009987, BC012653 NM_009987, BC012653 |
13051 |
1010 |
microglial cell activation positive regulation of neuroblast proliferation microglial cell activation involved in immune response negative regulation of chronic inflammatory response to non-antigenic stimulus response to ischemia cytokine receptor activity G protein-coupled receptor activity chemokine receptor activity plasma membrane chemotaxis immune response cell adhesion signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration memory external side of plasma membrane cell surface cell surface membrane integral component of membrane C-C chemokine receptor activity C-X3-C chemokine receptor activity negative regulation of angiogenesis cytokine-mediated signaling pathway calcium-mediated signaling C-C chemokine binding C-X3-C chemokine binding C-X3-C chemokine binding central nervous system maturation cerebral cortex cell migration negative regulation of cell migration regulation of tumor necrosis factor production negative regulation of interleukin-1 beta production neuronal cell body membrane social behavior autocrine signaling neuron projection innate immune response regulation of nitric oxide biosynthetic process positive regulation of angiogenesis macrophage chemotaxis perinuclear region of cytoplasm positive regulation of neurogenesis modulation of chemical synaptic transmission leukocyte tethering or rolling positive regulation of NF-kappaB transcription factor activity positive regulation of protein kinase B signaling synapse maturation cell chemotaxis cell chemotaxis chemokine-mediated signaling pathway cellular response to lipopolysaccharide dendritic tree negative regulation of hippocampal neuron apoptotic process multiple spine synapse organization, single dendrite negative regulation of long-term synaptic potentiation positive regulation of I-kappaB phosphorylation positive regulation of microglial cell migration negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
04060 04062 |
| TC1300001349.mm.2 |
Tmem267 |
transmembrane protein 267 |
13 |
119488472, 119488085 |
NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 |
633640 |
12 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC1200000719.mm.2 |
Rad51b |
RAD51 paralog B |
12 |
79297281, 79297350 |
NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184 |
19363 |
22 |
nucleotide binding four-way junction DNA binding four-way junction DNA binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination in utero embryonic development in utero embryonic development blastocyst growth DNA binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding ATP binding nucleus replication fork replication fork DNA repair DNA recombination cellular response to DNA damage stimulus DNA-dependent ATPase activity DNA-dependent ATPase activity positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle Rad51B-Rad51C-Rad51D-XRCC2 complex Rad51B-Rad51C-Rad51D-XRCC2 complex somite development |
03440 |
| TC1300001445.mm.2 |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
13 |
-12186539 |
NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685 |
238505 |
25 |
folic acid binding cytoplasm cytosol cytosol protein methylation methionine metabolic process methyltransferase activity zinc ion binding cellular amino acid biosynthetic process methionine synthase activity methionine synthase activity methionine synthase activity methionine biosynthetic process methionine biosynthetic process cobalamin metabolic process amino acid binding transferase activity axon regeneration cobalamin binding methylation pteridine-containing compound metabolic process cellular metabolic process tetrahydrofolate metabolic process metal ion binding response to axon injury homocysteine metabolic process cellular response to nitric oxide |
00270 00450 00670 01100 |
| TC1000003078.mm.2 |
Slc16a7 |
solute carrier family 16 (monocarboxylic acid transporters), member 7 |
10 |
-125219269, -125219269 |
NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960 NM_011391, BC117803, BC117804, BC126960 |
20503 |
44 |
nucleoplasm cytoplasm plasma membrane integral component of plasma membrane integral component of plasma membrane monocarboxylic acid transmembrane transporter activity lactate transmembrane transporter activity symporter activity monocarboxylic acid transport membrane integral component of membrane lactate transmembrane transport plasma membrane lactate transport pyruvate transmembrane transporter activity transmembrane transport Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse parallel fiber to Purkinje cell synapse glutamatergic synapse integral component of postsynaptic density membrane pyruvate transmembrane transport |
|
| TC0200005378.mm.2 |
Gm14326 |
predicted gene 14326 |
2 |
-177944590, -177935992 |
NM_001190302, NM_001282028 NM_001190302, NM_001282028 |
665211 |
9 |
molecular_function cellular_component biological_process |
|
| TC0800001263.mm.2 |
Nip7 |
NIP7, nucleolar pre-rRNA processing protein |
8 |
107056876 |
NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 |
66164 |
19 |
RNA binding nucleus nucleoplasm nucleolus nucleolus cytosol preribosome, large subunit precursor ribosome biogenesis ribosome assembly ribosomal large subunit biogenesis |
|
| TC1700002794.mm.2 |
|
|
|
|
NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 |
|
|
molecular_function protein binding cellular_component cytosol cytoplasmic dynein complex microtubule-based movement biological_process extrinsic component of membrane sperm flagellum |
|
| TC1700002497.mm.2 |
Ndc80 |
NDC80 kinetochore complex component |
17 |
-71496099 |
NM_023294, BC020131 NM_023294, BC020131 |
67052 |
29 |
mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome outer kinetochore protein binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cell cycle mitotic spindle organization spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I chromosome segregation G2/MI transition of meiotic cell cycle attachment of spindle microtubules to kinetochore cyclin binding Ndc80 complex Ndc80 complex regulation of protein stability identical protein binding centrosome duplication cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore attachment of mitotic spindle microtubules to kinetochore kinetochore organization kinetochore organization positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of protein localization to kinetochore |
|
| TC0100002739.mm.2 |
Ncl |
nucleolin |
1 |
-86344718 |
NM_010880, BC005460 NM_010880, BC005460 |
17975 |
127 |
angiogenesis fibrillar center dense fibrillar component nucleic acid binding DNA binding single-stranded DNA binding RNA binding RNA binding signaling receptor binding calcium ion binding protein binding nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex chromosome nucleolus nucleolus cytoplasm cell cortex endocytosis protein C-terminus binding cell surface negative regulation of translation positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production selenocysteine insertion sequence binding cytoplasmic ribonucleoprotein granule rRNA primary transcript binding telomeric DNA binding histone binding identical protein binding negative regulation of apoptotic process laminin binding sequence-specific DNA binding DNA topoisomerase binding positive regulation of transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome mRNA 5'-UTR binding cellular response to lipopolysaccharide cellular response to epidermal growth factor stimulus positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ErbB-4 class receptor binding cellular response to leukemia inhibitory factor ribonucleoprotein complex regulation of rRNA processing |
|
| TC1400000174.mm.2 |
Zswim8 |
zinc finger SWIM-type containing 8 |
14 |
20707551 |
NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 NM_001252081, NM_001252082, NM_027996, BC151046, BC151056, BC151173, BC172103 |
268721 |
20 |
molecular_function cytosol zinc ion binding Cul2-RING ubiquitin ligase complex metal ion binding regulation of axon guidance |
|
| TC0900001908.mm.2 |
Anln |
anillin, actin binding protein |
9 |
-22331213 |
NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164 |
68743 |
47 |
mitotic cytokinesis mitotic cytokinesis actomyosin contractile ring assembly hematopoietic progenitor cell differentiation actin binding nucleus nucleoplasm cytoplasm actomyosin contractile ring actomyosin contractile ring cytoskeleton cell cycle actin cytoskeleton midbody septin ring organization bleb cell projection cell division glomerular visceral epithelial cell migration cell cortex region positive regulation of bleb assembly |
|
| TC1300000383.mm.2 |
Nqo2 |
N-ribosyldihydronicotinamide quinone reductase 2 |
13 |
33967152, 33964658 |
NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 |
18105 |
32 |
dihydronicotinamide riboside quinone reductase activity NAD(P)H dehydrogenase (quinone) activity nucleoplasm cytoplasm cytosol cytosol zinc ion binding electron transfer activity oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors chloride ion binding protein homodimerization activity positive regulation of neuron apoptotic process metal ion binding positive regulation of ERK1 and ERK2 cascade FAD binding melatonin binding positive regulation of vascular associated smooth muscle cell proliferation resveratrol binding positive regulation of reactive oxygen species metabolic process |
|
| TC1100003693.mm.2 |
Top2a |
topoisomerase (DNA) II alpha |
11 |
-98992946 |
NM_011623 |
21973 |
101 |
nucleotide binding nuclear chromosome magnesium ion binding resolution of meiotic recombination intermediates chromosome, centromeric region condensed chromosome condensed chromosome sister chromatid segregation hematopoietic progenitor cell differentiation DNA binding chromatin binding DNA topoisomerase activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm centriole DNA metabolic process DNA topological change DNA topological change DNA ligation cellular response to DNA damage stimulus chromosome segregation chromosome segregation chromosome segregation female meiotic nuclear division protein C-terminus binding DNA-dependent ATPase activity DNA binding, bending DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex isomerase activity enzyme binding chromosome condensation apoptotic chromosome condensation apoptotic chromosome condensation protein-containing complex embryonic cleavage regulation of circadian rhythm protein homodimerization activity histone deacetylase binding positive regulation of apoptotic process ubiquitin binding sequence-specific DNA binding positive regulation of single stranded viral RNA replication via double stranded DNA intermediate positive regulation of transcription by RNA polymerase II metal ion binding protein heterodimerization activity rhythmic process female meiosis chromosome separation negative regulation of DNA duplex unwinding ribonucleoprotein complex |
|
| TC1600001380.mm.2 |
Dgkg |
diacylglycerol kinase, gamma |
16 |
-22466568 |
NM_138650, BC015278 NM_138650, BC015278 |
110197 |
36 |
nucleotide binding NAD+ kinase activity diacylglycerol kinase activity diacylglycerol kinase activity diacylglycerol kinase activity calcium ion binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway lipid binding membrane kinase activity phosphorylation transferase activity intracellular signal transduction diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process glycerolipid metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding regulation of dendrite development negative regulation of protein kinase C signaling |
00561 00564 01100 04070 |
| TC0X00002826.mm.2 |
Taf9b |
TATA-box binding protein associated factor 9B |
X |
-106206873, -106206873 |
NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223 |
407786 |
20 |
negative regulation of transcription by RNA polymerase II nucleus transcription factor TFIID complex transcription factor TFIID complex DNA-templated transcription, initiation transcription by RNA polymerase II RNA polymerase II general transcription initiation factor activity positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptotic process protein heterodimerization activity protein stabilization |
03022 |
| TC0600000989.mm.2 |
C87436 |
expressed sequence C87436 |
6 |
86438673, 86438397, 86438645, 86438375 |
NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 |
232196 |
18 |
molecular_function nucleus nucleoplasm biological_process |
|
| TC0700002311.mm.2 |
Zik1 |
zinc finger protein interacting with K protein 1 |
7 |
-10487223 |
NM_009577, BC050942, BC067196 NM_009577, BC050942, BC067196 NM_009577, BC050942, BC067196 |
22775 |
21 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleic acid binding DNA binding intracellular anatomical structure nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II metal ion binding |
|
| TC1300000928.mm.2 |
Mctp1 |
multiple C2 domains, transmembrane 1 |
13 |
76384138, 76579596 |
NM_030174 |
78771 |
13 |
calcium ion binding calcium ion binding endosome endoplasmic reticulum membrane integral component of membrane integral component of membrane cell junction negative regulation of cell migration synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle synapse negative regulation of endocytosis metal ion binding regulation of neurotransmitter secretion recycling endosome negative regulation of response to oxidative stress |
|
| TC0500000928.mm.2 |
Anxa3 |
annexin A3 |
5 |
96793384 |
NM_013470, BC090634, BC141167 NM_013470, BC090634, BC141167 NM_013470, BC090634, BC141167 |
11745 |
28 |
phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding cytoplasm cytoplasm plasma membrane phagocytosis positive regulation of endothelial cell migration membrane phospholipase A2 inhibitor activity axon dendrite phagocytic vesicle membrane specific granule defense response to bacterium neuronal cell body neutrophil degranulation positive regulation of angiogenesis calcium-dependent protein binding positive regulation of DNA metabolic process positive regulation of DNA-binding transcription factor activity collagen-containing extracellular matrix |
|
| TC0400002460.mm.2 |
Ubap2 |
ubiquitin-associated protein 2 |
4 |
-41194314 |
NM_026872, BC007179 NM_026872, BC007179 |
68926 |
25 |
nucleus cytoplasm |
|
| TC0500001428.mm.2 |
Kntc1 |
kinetochore associated 1 |
5 |
123749725 |
NM_001042421 |
208628 |
20 |
chromosome, centromeric region kinetochore spindle pole molecular_function nucleus chromosome cytoplasm kinetochore microtubule cytosol cytoskeleton plasma membrane cell cycle mitotic spindle assembly checkpoint actin cytoskeleton cell division RZZ complex |
|
| TC0500000324.mm.2 |
Gpn1 |
GPN-loop GTPase 1 |
5 |
31494740 |
NM_133756, BC020174, BC096466 NM_133756, BC020174, BC096466 NM_133756, BC020174, BC096466 |
74254 |
17 |
nucleotide binding GTPase activity GTP binding nucleus nucleoplasm cytoplasm mitochondrion cytosol hydrolase activity |
|
| TC0200001947.mm.2 |
Polr1b |
polymerase (RNA) I polypeptide B |
2 |
129100995 |
NM_009086, BC060656 NM_009086, BC060656 |
20017 |
35 |
DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm chromosome nucleolus nucleolus RNA polymerase I complex RNA polymerase I complex RNA polymerase I complex cytosol transcription, DNA-templated embryo implantation rRNA transcription rRNA transcription embryo development transferase activity nucleotidyltransferase activity nucleologenesis ribonucleoside binding metal ion binding |
00230 00240 01100 03020 |
| TC0400001596.mm.2 |
Rpa2 |
replication protein A2 |
4 |
132768359 |
NM_011284, BC004578 NM_011284, BC004578 |
19891 |
46 |
telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region chromosome, telomeric region chromatin DNA binding damaged DNA binding single-stranded DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination cellular response to DNA damage stimulus regulation of double-strand break repair via homologous recombination nuclear body PML body enzyme binding protein phosphatase binding mitotic G1 DNA damage checkpoint ubiquitin protein ligase binding protein localization to chromosome site of double-strand break site of double-strand break protein N-terminus binding G-rich strand telomeric DNA binding regulation of DNA damage checkpoint |
03030 03420 03430 03440 |
| TC1100003124.mm.2 |
Nlrp1a |
NLR family, pyrin domain containing 1A |
11 |
-71091196 |
NM_001004142 |
195046 |
38 |
nucleotide binding protein binding ATP binding cytoplasm activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response response to muramyl dipeptide positive regulation of interleukin-1 beta production protein-containing complex defense response to bacterium regulation of apoptotic process neuronal cell body innate immune response inflammasome complex scaffold protein binding programmed necrotic cell death |
04621 |
| TC1100003945.mm.2 |
Nol11 |
nucleolar protein 11 |
11 |
-107166652 |
NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874 |
68979 |
19 |
nucleus nucleolus nucleolus rRNA processing maturation of SSU-rRNA maturation of SSU-rRNA t-UTP complex ribosome biogenesis positive regulation of transcription of nucleolar large rRNA by RNA polymerase I |
|
| TC0200003182.mm.2 |
Qsox2 |
quiescin Q6 sulfhydryl oxidase 2 |
2 |
-26209123 |
NM_153559, BC030934 NM_153559, BC030934 |
227638 |
17 |
protein disulfide isomerase activity extracellular space nucleoplasm Golgi apparatus protein folding membrane integral component of membrane oxidoreductase activity flavin-linked sulfhydryl oxidase activity thiol oxidase activity integral component of Golgi membrane cell redox homeostasis |
|
| TC0800002960.mm.2 |
Adat1 |
adenosine deaminase, tRNA-specific 1 |
8 |
-111970864, -111966897 |
NM_013925, BC019976 NM_013925, BC019976 |
30947 |
14 |
RNA binding adenosine deaminase activity cellular_component RNA processing tRNA processing tRNA-specific adenosine deaminase activity tRNA-specific adenosine deaminase activity hydrolase activity metal ion binding |
|
| TC0700002102.mm.2 |
Dhcr7 |
7-dehydrocholesterol reductase |
7 |
143830213, 143823166, 143823398 |
NM_007856, BC006854 NM_007856, BC006854 |
13360 |
56 |
blood vessel development nuclear outer membrane endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process post-embryonic development sterol delta7 reductase activity membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process brassinosteroid biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor cell differentiation integral component of endoplasmic reticulum membrane lung development multicellular organism growth regulation of cell population proliferation intracellular membrane-bounded organelle regulation of cholesterol biosynthetic process 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity |
00100 01100 |
| TC1000000047.mm.2 |
Nup43 |
nucleoporin 43 |
10 |
7667503 |
NM_145706, BC011060 NM_145706, BC011060 |
69912 |
16 |
chromosome, centromeric region kinetochore molecular_function nucleus nuclear pore nucleoplasm chromosome cytosol cell cycle chromosome segregation protein transport nuclear speck nuclear pore outer ring nuclear pore outer ring mRNA transport cell division |
03013 |
| TC0800001390.mm.2 |
Cenpn |
centromere protein N |
8 |
116921739 |
NM_028131, BC058243 NM_028131, BC058243 |
72155 |
14 |
chromosome, centromeric region kinetochore molecular_function nucleus nucleoplasm chromosome chromosome segregation kinetochore assembly |
|
| MG-1-neg-10338216_st |
|
|
|
|
|
|
|
|
|
| TC0200004808.mm.2 |
Thbd |
thrombomodulin |
2 |
-148404470 |
NM_009378, BC019154 NM_009378, BC019154 |
21824 |
120 |
transmembrane signaling receptor activity calcium ion binding extracellular space vacuolar membrane plasma membrane plasma membrane integral component of plasma membrane female pregnancy blood coagulation hemostasis embryo development external side of plasma membrane cell surface membrane integral component of membrane apicolateral plasma membrane negative regulation of blood coagulation negative regulation of coagulation |
04610 |
| TC0800002313.mm.2 |
Msmo1 |
methylsterol monoxygenase 1 |
8 |
-64718122 |
NM_025436, BC006802 NM_025436, BC006802 |
66234 |
31 |
C-4 methylsterol oxidase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process lipid biosynthetic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity |
00100 01100 |
| TC0X00003412.mm.2 |
Ccdc22 |
coiled-coil domain containing 22 |
X |
-7593808 |
NM_138603, BC011195 NM_138603, BC011195 |
54638 |
17 |
protein binding endosome cellular copper ion homeostasis Golgi to plasma membrane transport cytoplasmic sequestering of NF-kappaB protein transport endocytic recycling cholesterol homeostasis positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling regulation of plasma lipoprotein particle levels cullin family protein binding cullin family protein binding retrograde transport, endosome to plasma membrane positive regulation of ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-dependent protein catabolic process |
|
| TC0600001462.mm.2 |
Vwf |
Von Willebrand factor |
6 |
125552947 |
NM_011708 |
22371 |
313 |
liver development placenta development protease binding integrin binding extracellular matrix structural constituent protein binding collagen binding extracellular region extracellular space extracellular space extracellular space cytoplasm endoplasmic reticulum cell adhesion blood coagulation blood coagulation blood coagulation hemostasis hemostasis hemostasis external side of plasma membrane immunoglobulin binding platelet activation extracellular matrix cell-substrate adhesion cell-substrate adhesion cell-substrate adhesion Weibel-Palade body identical protein binding protein N-terminus binding chaperone binding collagen-containing extracellular matrix collagen-containing extracellular matrix |
04510 04512 04610 |
| TC0100000858.mm.2 |
Agap1 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
1 |
89454810 |
NM_001037136, NM_178119, BC172673 NM_001037136, NM_178119, BC172673 NM_001037136, NM_178119, BC172673 |
347722 |
29 |
nucleotide binding GTPase activity GTPase activator activity GTP binding phospholipid binding nucleus cytoplasm cytosol protein transport metal ion binding |
04144 |
| TC0100002354.mm.2 |
Hspd1 |
heat shock protein 1 (chaperonin) |
1 |
-55077833, -55077832 |
NM_010477, BC016400 NM_010477, BC016400 |
15510 |
137 |
nucleotide binding lipopolysaccharide binding lipopolysaccharide binding p53 binding MyD88-dependent toll-like receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell double-stranded RNA binding ATP binding extracellular space cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial matrix mitochondrial matrix early endosome peroxisomal matrix rough endoplasmic reticulum Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein folding activation of cysteine-type endopeptidase activity involved in apoptotic process response to unfolded protein high-density lipoprotein particle binding apoptotic mitochondrial changes apoptotic mitochondrial changes cell surface membrane isomerase activity enzyme binding mitochondrial crista coated vesicle secretory granule secretory granule ubiquitin protein ligase binding Golgi cisterna positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production protein-containing complex apolipoprotein binding apolipoprotein A-I binding mitochondrial unfolded protein response protein refolding B cell proliferation T cell activation T cell activation T cell activation T cell activation B cell activation zymogen granule positive regulation of macrophage activation positive regulation of apoptotic process negative regulation of apoptotic process myelin sheath intracellular membrane-bounded organelle negative regulation of neuron apoptotic process protein-containing complex binding protein import into mitochondrial intermembrane space membrane raft lipopolysaccharide receptor complex isotype switching to IgG isotypes positive regulation of inflammatory response protein stabilization positive regulation of T cell activation positive regulation of T cell activation positive regulation of T cell activation chaperone binding chaperone binding biological process involved in interaction with symbiont extracellular exosome negative regulation of apoptotic process in bone marrow cell cellular response to interleukin-7 modification-dependent protein binding negative regulation of reactive oxygen species biosynthetic process |
03018 04940 |
| TC0500002240.mm.2 |
Nop14 |
NOP14 nucleolar protein |
5 |
-34638535 |
NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043 |
75416 |
21 |
nucleus nucleoplasm nucleolus nucleolus rRNA processing enzyme binding maturation of SSU-rRNA Noc4p-Nop14p complex small-subunit processome ribosome biogenesis |
|
| TC1600000335.mm.2 |
St6gal1 |
beta galactoside alpha 2,6 sialyltransferase 1 |
16 |
23226020, 23290469, 23224739 |
NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 |
20440 |
78 |
Golgi trans cisterna Golgi membrane beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity extracellular region endoplasmic reticulum Golgi apparatus Golgi medial cisterna N-acetylneuraminate metabolic process protein glycosylation sialyltransferase activity sialyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine positive regulation of mononuclear cell proliferation protein homodimerization activity negative regulation of chemotaxis sialylation regulation of substrate adhesion-dependent cell spreading protein sialylation negative regulation of macrophage apoptotic process |
00510 00514 01100 |
| TC0100001656.mm.2 |
Exo1 |
exonuclease 1 |
1 |
175880777 |
NM_012012, BC006671 NM_012012, BC006671 |
26909 |
51 |
immune system process humoral immune response mediated by circulating immunoglobulin DNA binding chromatin binding catalytic activity nuclease activity endonuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane nucleobase-containing compound metabolic process DNA repair mismatch repair mismatch repair DNA recombination DNA recombination cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes nuclear body hydrolase activity hydrolase activity, acting on ester bonds 5'-flap endonuclease activity 5'-3' exodeoxyribonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity isotype switching metal ion binding flap endonuclease activity meiotic cell cycle double-stranded DNA 5'-3' exodeoxyribonuclease activity |
03430 |
| TC0100000351.mm.2 |
Wdr75 |
WD repeat domain 75 |
1 |
45795165 |
NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881 |
73674 |
23 |
nucleus nucleolus rRNA processing ribosome biogenesis positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing |
03008 |
| TC0500003219.mm.2 |
Camkk2 |
calcium/calmodulin-dependent protein kinase kinase 2, beta |
5 |
-122731169 |
NM_001199676, NM_145358, BC023103 NM_001199676, NM_145358, BC023103 NM_001199676, NM_145358, BC023103 |
207565 |
67 |
nucleotide binding positive regulation of protein phosphorylation protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calcium ion binding protein binding calmodulin binding ATP binding nucleus cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity activation of protein kinase activity cell projection protein autophosphorylation CAMKK-AMPK signaling cascade |
04920 |
| TC0500002650.mm.2 |
Noa1 |
nitric oxide associated 1 |
5 |
-77294168 |
NM_019836, BC017154 NM_019836, BC017154 |
56412 |
24 |
nucleotide binding GTP binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane apoptotic process regulation of cell death regulation of cell death regulation of cell death membrane extrinsic component of mitochondrial inner membrane mitochondrial translation regulation of cellular respiration regulation of cellular respiration |
|
| TC1100003780.mm.2 |
Kat2a |
K(lysine) acetyltransferase 2A |
11 |
-100704745 |
NM_001038010, NM_020004, BC063752 NM_001038010, NM_020004, BC063752 NM_001038010, NM_020004, BC063752 |
14534 |
93 |
histone acetyltransferase complex histone acetyltransferase complex chromatin in utero embryonic development somitogenesis somitogenesis cytokine production neural tube closure chromatin binding chromatin binding transcription coactivator activity histone acetyltransferase activity histone acetyltransferase activity protein binding nucleus nucleus Ada2/Gcn5/Ada3 transcription activator complex Ada2/Gcn5/Ada3 transcription activator complex chromosome cytoplasm centrosome cytoskeleton regulation of transcription, DNA-templated nervous system development long-term memory N-acetyltransferase activity transcription factor binding transcription factor binding cell population proliferation H3 histone acetyltransferase activity H3 histone acetyltransferase activity acetyltransferase activity histone acetylation histone deubiquitination transferase activity transferase activity, transferring acyl groups internal peptidyl-lysine acetylation protein phosphatase binding telencephalon development metencephalon development midbrain development STAGA complex STAGA complex positive regulation of cell projection organization regulation of protein stability transcription factor TFTC complex positive regulation of histone acetylation multicellular organism growth histone deacetylase binding histone H3 acetylation histone H3 acetylation histone H4-K12 acetylation histone acetyltransferase activity (H4-K12 specific) histone H3-K14 acetylation oxoglutarate dehydrogenase complex regulation of regulatory T cell differentiation positive regulation of gluconeogenesis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of centriole replication regulation of synaptic plasticity intracellular distribution of mitochondria regulation of T cell activation regulation of cartilage development peptide-lysine-N-acetyltransferase activity alpha-tubulin acetylation mitotic spindle histone succinylation histone succinyltransferase activity peptidyl-lysine glutarylation histone glutaryltransferase activity regulation of bone development regulation of stem cell population maintenance positive regulation of cardiac muscle cell differentiation |
04330 |
| TSUnmapped00000020.mm.2 |
Snx29 |
sorting nexin 29 |
16 |
11322903, 11405647 |
NM_001290148 |
74478 |
15 |
molecular_function biological_process phosphatidylinositol binding |
|
| TC0400002854.mm.2 |
Tle1 |
transducin-like enhancer of split 1 |
4 |
-72157579, -72109944 |
NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 NM_001285529, NM_001285530, NM_001285531, NM_001285532, NM_011599, BC057573 |
21885 |
85 |
negative regulation of transcription by RNA polymerase II chromatin binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription factor binding positive regulation of gene expression Wnt signaling pathway identical protein binding negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of transcription, DNA-templated repressing transcription factor binding negative regulation of canonical Wnt signaling pathway beta-catenin-TCF complex negative regulation of anoikis |
|
| TC0700004201.mm.2 |
Cdr2 |
cerebellar degeneration-related 2 |
7 |
-120957039, -120957036 |
NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511 |
12585 |
20 |
molecular_function cytoplasm biological_process |
|
| TC0200001757.mm.2 |
Knl1 |
kinetochore scaffold 1 |
2 |
119047118, 119047118 |
NM_029617, BC080815 NM_029617, BC080815 |
76464 |
19 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore acrosomal vesicle molecular_function nucleus nucleus nucleoplasm chromosome cell cycle chromosome segregation attachment of spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore negative regulation of phosphatase activity nuclear body protein localization to kinetochore protein localization to kinetochore cell division |
|
| TC0900002007.mm.2 |
Dcps |
decapping enzyme, scavenger |
9 |
-35124413 |
NM_027030, BC016273 NM_027030, BC016273 |
69305 |
22 |
deadenylation-dependent decapping of nuclear-transcribed mRNA RNA 7-methylguanosine cap binding RNA 7-methylguanosine cap binding P-body nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol mRNA processing RNA splicing hydrolase activity cellular response to menadione identical protein binding negative regulation of programmed cell death mRNA cis splicing, via spliceosome m7G(5')pppN diphosphatase activity m7G(5')pppN diphosphatase activity |
03018 |
| TC0700000786.mm.2 |
Klk1b11 |
kallikrein 1-related peptidase b11 |
7 |
43995876 |
NM_010640, BC013660 NM_010640, BC013660 |
16613 |
13 |
regulation of systemic arterial blood pressure endopeptidase activity serine-type endopeptidase activity extracellular space proteolysis peptidase activity serine-type peptidase activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides secretory granule zymogen activation protein-containing complex |
|
| TC1000002639.mm.2 |
Parpbp |
PARP1 binding protein |
10 |
-88091397 |
NM_029249, BC070476 NM_029249, BC070476 |
75317 |
21 |
chromatin chromatin DNA binding protein binding nucleus nucleoplasm cytoplasm DNA repair cellular response to DNA damage stimulus negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC0700001989.mm.2 |
Lrrc27 |
leucine rich repeat containing 27 |
7 |
139212987, 139213274 |
NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816 |
76612 |
11 |
molecular_function |
|
| TC1500001742.mm.2 |
Top1mt |
DNA topoisomerase 1, mitochondrial |
15 |
-75657032 |
NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 |
72960 |
21 |
DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity nucleoplasm chromosome mitochondrion mitochondrion DNA replication DNA topological change isomerase activity mitochondrial nucleoid mitochondrial nucleoid |
|
| TC0400001006.mm.2 |
Alg6 |
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase) |
4 |
99715629 |
NM_001081264, BC050854 NM_001081264, BC050854 |
320438 |
15 |
endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity glucosyltransferase activity |
00510 01100 |
| TC0600003148.mm.2 |
Cd9 |
CD9 antigen |
6 |
-125460265 |
NM_007657, BC070474, CD9 NM_007657, BC070474, CD9 NM_007657, BC070474, CD9 |
12527 |
130 |
integrin binding integrin binding protein binding extracellular region plasma membrane plasma membrane integral component of plasma membrane cell adhesion single fertilization fusion of sperm to egg plasma membrane involved in single fertilization fusion of sperm to egg plasma membrane involved in single fertilization negative regulation of cell population proliferation glial cell migration external side of plasma membrane cell surface myoblast fusion involved in skeletal muscle regeneration membrane integral component of membrane apical plasma membrane paranodal junction assembly receptor internalization protein-containing complex sperm-egg recognition negative regulation of cellular component movement extracellular exosome extracellular exosome cellular response to low-density lipoprotein particle stimulus negative regulation of platelet aggregation regulation of macrophage migration |
04640 |
| TC1800001654.mm.2 |
Rbfa |
ribosome binding factor A |
18 |
-80192263 |
NM_199197, BC064066 NM_199197, BC064066 |
68731 |
17 |
molecular_function cellular_component mitochondrion rRNA processing |
|
| TC0200002731.mm.2 |
Gm2026 |
predicted gene 2026 |
2 |
-175192004, -175419390, 175640390, 175737941, -176470368, -176619932 |
NM_001177543 |
100039060 |
9 |
cellular_component |
|
| TC0200001012.mm.2 |
Klhl23 |
kelch-like 23 |
2 |
69822369, 69821940, 69822840 |
NM_177784, BC072626 NM_177784, BC072626 |
277396 |
15 |
|
|
| TC1000002043.mm.2 |
|
|
|
|
NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 |
|
|
in utero embryonic development adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity protein binding cytosol cytosol polyamine biosynthetic process spermine biosynthetic process spermine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process lyase activity carboxy-lyase activity putrescine binding putrescine binding identical protein binding |
|
| TC1300001631.mm.2 |
H4c6 |
H4 clustered histone 6 |
13 |
-23551285 |
NM_175655, BC156748 NM_175655, BC156748 |
319157 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation |
05322 |
| TC1700001163.mm.2 |
Ttc27 |
tetratricopeptide repeat domain 27 |
17 |
74717749 |
NM_152817, BC021912 NM_152817, BC021912 |
74196 |
18 |
molecular_function cellular_component biological_process |
|
| TC1200001834.mm.2 |
Mis18bp1 |
MIS18 binding protein 1 |
12 |
-65132734 |
NM_172578, BC052175 NM_172578, BC052175 |
217653 |
24 |
chromosome, centromeric region condensed nuclear chromosome kinetochore DNA binding protein binding nucleus chromosome cell cycle cell division |
|
| TC1700000657.mm.2 |
Lsm2 |
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated |
17 |
34982129, 34981853, 34982129, 34981853 |
NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 |
27756 |
32 |
spliceosomal tri-snRNP complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding protein binding nucleus nucleoplasm spliceosomal complex U6 snRNP cytoplasm mRNA processing mRNA catabolic process RNA splicing protein kinase binding small GTPase binding U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
03018 03040 |
| TC1600000238.mm.2 |
Trmt2a |
TRM2 tRNA methyltransferase 2A |
16 |
18248882 |
NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 NM_001080999, NM_001081000, NM_001195205, BC027431, BC038486, BC046976 |
15547 |
40 |
nucleic acid binding RNA binding RNA processing methyltransferase activity RNA methyltransferase activity transferase activity methylation |
|
| TC0200004537.mm.2 |
Atp8b4 |
ATPase, class I, type 8B, member 4 |
2 |
-126320972, -126320972 |
NM_001080944 |
241633 |
12 |
Golgi apparatus trans-Golgi network plasma membrane plasma membrane Golgi organization phospholipid translocation ATPase-coupled intramembrane lipid transporter activity |
|
| TC0300000624.mm.2 |
4930579G24Rik |
RIKEN cDNA 4930579G24 gene |
3 |
79629078 |
NM_029482 |
75939 |
8 |
molecular_function cellular_component cytoplasm biological_process |
|
| TC1900001622.mm.2 |
Calhm2 |
calcium homeostasis modulator family member 2 |
19 |
-47132231 |
NM_133746, BC019197 NM_133746, BC019197 |
72691 |
13 |
cation channel activity integral component of plasma membrane ion transport membrane integral component of membrane positive regulation of apoptotic process |
|
| TC1200001012.mm.2 |
Rin3 |
Ras and Rab interactor 3 |
12 |
102283073, 102283640 |
NM_001161365, NM_177620, BC137907 NM_001161365, NM_177620, BC137907 NM_001161365, NM_177620, BC137907 |
217835 |
16 |
negative regulation of receptor internalization guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm endosome early endosome signal transduction endocytic vesicle axon dendrite small GTPase binding cytoplasmic vesicle vesicle neuronal cell body negative regulation of mast cell chemotaxis regulation of vesicle size |
|
| TC0200004376.mm.2 |
Dph6 |
diphthamine biosynthesis 6 |
2 |
-114516417 |
NM_025675, BC022995 NM_025675, BC022995 |
66632 |
17 |
nucleotide binding ATP binding nucleoplasm nucleolus ligase activity diphthine-ammonia ligase activity diphthine-ammonia ligase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
|
| MG-1-neg-10339930_st |
|
|
|
|
|
|
|
|
|
| TC1300001635.mm.2 |
H2bc7 |
H2B clustered histone 7 |
13 |
-23573759 |
NM_178195, BC160307 NM_178195, BC160307 |
319180 |
6 |
innate immune response in mucosa DNA binding extracellular space nucleoplasm cytosol nucleosome assembly antibacterial humoral response identical protein binding defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide |
05322 |
| TC0200005271.mm.2 |
Aurka |
aurora kinase A |
2 |
-172356189 |
NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711 |
20878 |
115 |
nucleotide binding meiotic spindle organization microtubule cytoskeleton organization mitotic cell cycle protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm cytoplasm centrosome centrosome microtubule organizing center spindle cytosol cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cilium protein phosphorylation protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle organization spindle assembly involved in female meiosis I centrosome cycle mitotic centrosome separation mitotic centrosome separation response to wounding anterior/posterior axis specification negative regulation of gene expression microtubule cytoskeleton kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation protein kinase binding cell projection organization spindle pole centrosome spindle pole centrosome ubiquitin protein ligase binding regulation of protein stability negative regulation of protein binding chromosome passenger complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis histone serine kinase activity histone serine kinase activity germinal vesicle cell projection negative regulation of apoptotic process axon hillock pronucleus protein heterodimerization activity perinuclear region of cytoplasm spindle midzone cell division meiotic cell cycle centrosome localization protein localization to centrosome mitotic spindle meiotic spindle negative regulation of spindle checkpoint liver regeneration mitotic spindle pole positive regulation of oocyte maturation neuron projection extension |
04114 |
| TC1500001823.mm.2 |
Foxred2 |
FAD-dependent oxidoreductase domain containing 2 |
15 |
-77940521 |
NM_001017983, NM_001168260, BC086662 NM_001017983, NM_001168260, BC086662 NM_001017983, NM_001168260, BC086662 |
239554 |
12 |
endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum lumen oxidoreductase activity ubiquitin-dependent ERAD pathway ubiquitin-dependent ERAD pathway flavin adenine dinucleotide binding |
|
| TC1000002443.mm.2 |
Pwp2 |
PWP2 periodic tryptophan protein homolog (yeast) |
10 |
-78170909 |
NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480 |
110816 |
23 |
ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC1900001472.mm.2 |
Noc3l |
NOC3 like DNA replication regulator |
19 |
-38788127 |
NM_021315, BC031132 NM_021315, BC031132 |
57753 |
29 |
chromatin binding nucleus nucleoplasm nucleolus nucleolus nucleolus mitochondrion DNA replication initiation nuclear speck fat cell differentiation |
|
| TC0500002095.mm.2 |
Prkag2 |
protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
5 |
-24862734, -24862734, -24862734 |
NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 |
108099 |
37 |
nucleotide binding AMP-activated protein kinase activity AMP-activated protein kinase activity cAMP-dependent protein kinase inhibitor activity ATP binding nucleus nucleoplasm cytoplasm cytosol glycogen metabolic process regulation of glycolytic process protein phosphorylation negative regulation of protein kinase activity lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process cAMP-dependent protein kinase regulator activity phosphorylase kinase regulator activity positive regulation of peptidyl-threonine phosphorylation AMP binding AMP binding regulation of fatty acid metabolic process protein kinase regulator activity protein kinase binding protein kinase binding protein kinase activator activity nucleotide-activated protein kinase complex nucleotide-activated protein kinase complex adenyl ribonucleotide binding intracellular signal transduction cellular response to glucose starvation ADP binding positive regulation of protein kinase activity regulation of catalytic activity regulation of catalytic activity regulation of protein serine/threonine kinase activity |
04910 04920 05410 |
| TC0300002352.mm.2 |
Cks1b |
CDC28 protein kinase 1b |
3 |
-89415471 |
NM_016904, BC076579 NM_016904, BC076579 |
54124 |
38 |
cyclin-dependent protein kinase holoenzyme complex regulation of transcription, DNA-templated cell cycle regulation of mitotic cell cycle cell population proliferation embryo development cyclin-dependent protein serine/threonine kinase regulator activity SCF ubiquitin ligase complex protein kinase binding histone binding ubiquitin binding mitotic cell cycle phase transition cell division cyclin-dependent protein serine/threonine kinase activator activity |
05200 05222 |
| TC0100003477.mm.2 |
|
|
|
|
|
|
|
|
|
| TC1200000988.mm.2 |
Tdp1 |
tyrosyl-DNA phosphodiesterase 1 |
12 |
99884517, 99884517 |
NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162 |
104884 |
35 |
single strand break repair single strand break repair single strand break repair double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding nuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane DNA repair DNA repair double-strand break repair double-strand break repair cellular response to DNA damage stimulus phosphoric diester hydrolase activity hydrolase activity 3'-tyrosyl-DNA phosphodiesterase activity 3'-tyrosyl-DNA phosphodiesterase activity intracellular membrane-bounded organelle |
|
| TC0200001881.mm.2 |
Dut |
deoxyuridine triphosphatase |
2 |
125247247, 125247514 |
NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 |
110074 |
32 |
magnesium ion binding dUTP diphosphatase activity dUTP diphosphatase activity nucleus nucleoplasm cytoplasm mitochondrion cytosol dUMP biosynthetic process dUMP biosynthetic process receptor inhibitor activity pyrimidine deoxyribonucleotide binding identical protein binding peroxisome proliferator activated receptor binding regulation of protein-containing complex assembly dUTP catabolic process dUTP catabolic process |
00240 01100 |
| TC0100003021.mm.2 |
Zranb3 |
zinc finger, RAN-binding domain containing 3 |
1 |
-127954178, -127954178, -127954178 |
NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 |
226409 |
20 |
nucleotide binding nucleic acid binding catalytic activity helicase activity nuclease activity endonuclease activity endodeoxyribonuclease activity endodeoxyribonuclease activity ATP binding nucleus nucleoplasm chromosome DNA repair DNA repair cellular response to DNA damage stimulus metabolic process response to UV hydrolase activity replication fork processing replication fork processing DNA rewinding annealing helicase activity nuclear replication fork nuclear replication fork negative regulation of DNA recombination metal ion binding replication fork protection replication fork protection K63-linked polyubiquitin modification-dependent protein binding |
|
| TC1700002795.mm.2 |
|
|
|
|
NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 NM_001123367, NM_001123368, BC061136, BC131981, BC131983 |
|
|
molecular_function protein binding cellular_component cytosol cytoplasmic dynein complex microtubule-based movement biological_process extrinsic component of membrane sperm flagellum |
|
| TC0X00001323.mm.2 |
Bex3 |
brain expressed X-linked 3 |
X |
136270252 |
NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 |
12070 |
35 |
signaling receptor binding death receptor binding nucleus cytoplasm cytoplasm cytosol cytosol cytosol apoptotic process signal transduction extrinsic apoptotic signaling pathway via death domain receptors identical protein binding metal ion binding |
04722 |
| TC0200005339.mm.2 |
|
|
|
|
NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC0800002529.mm.2 |
Gab1 |
growth factor receptor bound protein 2-associated protein 1 |
8 |
-80764433, -80764430 |
NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659 |
14388 |
95 |
activation of MAPK activity angiogenesis protein binding cytoplasm cytosol cell-cell junction response to oxidative stress signal transduction epidermal growth factor receptor signaling pathway activation of JUN kinase activity heart development epidermis development regulation of cell migration actin cytoskeleton reorganization response to hepatocyte growth factor cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor signaling pathway positive regulation of cell migration by vascular endothelial growth factor signaling pathway positive regulation of MAPK cascade positive regulation of angiogenesis platelet-derived growth factor receptor signaling pathway labyrinthine layer development interleukin-6-mediated signaling pathway endothelial cell chemotaxis to vascular endothelial growth factor |
04012 04722 05100 05211 |
| TC0200001002.mm.2 |
Nostrin |
nitric oxide synthase trafficker |
2 |
69135799 |
NM_181547, BC069942 NM_181547, BC069942 |
329416 |
17 |
DNA binding protein binding nucleus cytoplasm cytoskeleton plasma membrane endocytosis signal transduction membrane cytoplasmic vesicle negative regulation of transcription, DNA-templated |
|
| TC0700001343.mm.2 |
Nars2 |
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative) |
7 |
96951526 |
NM_153591, BC030041 NM_153591, BC030041 |
244141 |
18 |
nucleotide binding nucleic acid binding aminoacyl-tRNA ligase activity asparagine-tRNA ligase activity ATP binding nucleoplasm mitochondrion mitochondrion cytosol translation tRNA aminoacylation for protein translation asparaginyl-tRNA aminoacylation ligase activity |
00970 |
| TC0200005350.mm.2 |
|
|
|
|
NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC1100004056.mm.2 |
|
|
|
|
XR_106365 |
|
|
|
|
| TC1200001908.mm.2 |
Dhrs7 |
dehydrogenase/reductase (SDR family) member 7 |
12 |
-72650352 |
NM_025522, BC016189 NM_025522, BC016189 |
66375 |
18 |
biological_process oxidoreductase activity |
|
| TC0800000371.mm.2 |
Fut10 |
fucosyltransferase 10 |
8 |
31187330, 31187330 |
NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 |
171167 |
17 |
Golgi membrane nucleoplasm endoplasmic reticulum Golgi apparatus protein glycosylation fucosyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups cerebral cortex radially oriented cell migration fucosylation alpha-(1->3)-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity neuronal stem cell population maintenance |
|
| TC1100003941.mm.2 |
Kpna2 |
karyopherin (importin) alpha 2 |
11 |
-106988628 |
NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 |
16647 |
97 |
protein binding nucleus nucleoplasm nucleoplasm nucleoplasm cytosol cytosol protein import into nucleus NLS-bearing protein import into nucleus NLS-bearing protein import into nucleus nuclear localization sequence binding nuclear localization sequence binding cytoplasmic stress granule histone deacetylase binding nuclear import signal receptor activity nuclear import signal receptor activity repressing transcription factor binding entry of viral genome into host nucleus through nuclear pore complex via importin entry of viral genome into host nucleus through nuclear pore complex via importin extrinsic component of postsynaptic specialization membrane glutamatergic synapse postsynapse to nucleus signaling pathway positive regulation of viral life cycle positive regulation of viral life cycle |
|
| TC0800000912.mm.2 |
Rnf150 |
ring finger protein 150 |
8 |
82863355 |
NM_177378, BC160221 NM_177378, BC160221 |
330812 |
10 |
cytoplasm ubiquitin-dependent protein catabolic process membrane integral component of membrane metal ion binding ubiquitin protein ligase activity |
|
| TC1200001861.mm.2 |
Pole2 |
polymerase (DNA directed), epsilon 2 (p59 subunit) |
12 |
-69201778 |
NM_011133, BC063772 NM_011133, BC063772 |
18974 |
23 |
DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA replication DNA-dependent DNA replication epsilon DNA polymerase complex epsilon DNA polymerase complex nuclear body error-prone translesion synthesis intracellular membrane-bounded organelle |
00230 00240 01100 03030 03410 03420 |
| TC0400000567.mm.2 |
Smc2 |
structural maintenance of chromosomes 2 |
4 |
52439220 |
NM_008017, BC094380 NM_008017, BC094380 |
14211 |
37 |
single strand break repair nucleotide binding nuclear chromosome condensed chromosome condensed chromosome condensin complex condensin complex condensin complex condensin complex chromatin binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cell cycle mitotic chromosome condensation meiotic chromosome condensation chromosome condensation meiotic chromosome segregation chromosome organization cell division kinetochore organization |
|
| TC0500003418.mm.2 |
Cux1 |
cut-like homeobox 1 |
5 |
-136248134, -136266409, -136266409, -136248134 |
NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847 |
13047 |
445 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific kidney development DNA binding chromatin binding nucleus nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II intra-Golgi vesicle-mediated transport multicellular organism development membrane integral component of membrane integral component of Golgi membrane lung development inner ear auditory receptor cell differentiation neuron projection sequence-specific DNA binding positive regulation of dendrite morphogenesis |
|
| TC0500002059.mm.2 |
Pus7 |
pseudouridylate synthase 7 |
5 |
-23740164, -23740164 |
NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 |
78697 |
18 |
pseudouridine synthesis RNA binding nucleus nucleus tRNA processing RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity negative regulation of translation enzyme binding tRNA pseudouridine synthesis regulation of hematopoietic stem cell differentiation mRNA pseudouridine synthesis regulation of mesoderm development |
|
| TC0700004188.mm.2 |
Thumpd1 |
THUMP domain containing 1 |
7 |
-119715093 |
NM_145585, BC004776 NM_145585, BC004776 |
233802 |
21 |
RNA binding cellular_component tRNA modification |
|
| TC1000001601.mm.2 |
|
|
|
|
NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908 NM_172790, NR_105879, BC117907, BC117908 |
|
|
molecular_function cellular_component biological_process |
|
| TC1800001368.mm.2 |
Marchf3 |
membrane associated ring-CH-type finger 3 |
18 |
-56761715, -56775146 |
NM_177115, BC107232, BC107233 NM_177115, BC107232, BC107233 NM_177115, BC107232, BC107233 |
320253 |
15 |
ubiquitin-protein transferase activity lysosome endosome endocytosis zinc ion binding membrane integral component of membrane protein ubiquitination transferase activity cytoplasmic vesicle intracellular membrane-bounded organelle metal ion binding |
|
| TC0300003226.mm.2 |
Gm5150 |
predicted gene 5150 |
3 |
-15948069 |
NM_001081687, BC156687 NM_001081687, BC156687 |
381484 |
3 |
molecular_function plasma membrane positive regulation of phagocytosis positive regulation of T cell activation |
|
| TC0700001442.mm.2 |
Anapc15 |
anaphase promoting complex C subunit 15 |
7 |
101881324, 101896330, 101885859 |
NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730 |
75430 |
20 |
molecular_function anaphase-promoting complex cell cycle cell division regulation of mitotic cell cycle spindle assembly checkpoint |
|
| TC1500001300.mm.2 |
Otulinl |
OTU deubiquitinase with linear linkage specificity like |
15 |
-27655070 |
NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328 NM_001242423, NM_001242424, NM_198301, BC052328 |
223433 |
15 |
molecular_function nucleus nuclear envelope cytoplasm endoplasmic reticulum biological_process membrane extrinsic component of endoplasmic reticulum membrane |
|
| TC1600000464.mm.2 |
Osbpl11 |
oxysterol binding protein-like 11 |
16 |
33185070 |
NM_176840, BC035278 NM_176840, BC035278 |
106326 |
25 |
nucleoplasm endosome Golgi apparatus cytosol lipid transport lipid binding positive regulation of sequestering of triglyceride sterol transporter activity membrane sterol binding intracellular membrane-bounded organelle fat cell differentiation |
|
| TC1700002286.mm.2 |
Sgo1 |
shugoshin 1 |
17 |
-53674786 |
NM_028232, BC089014 NM_028232, BC089014 |
72415 |
41 |
mitotic sister chromatid segregation chromosome, centromeric region chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region spindle pole nucleus nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton cell cycle chromosome segregation attachment of spindle microtubules to kinetochore centriole-centriole cohesion centriole-centriole cohesion kinase binding meiotic chromosome segregation homologous chromosome segregation meiotic sister chromatid cohesion cell division mitotic sister chromatid cohesion, centromeric |
04114 |
| TC0200004665.mm.2 |
Rassf2 |
Ras association (RalGDS/AF-6) domain family member 2 |
2 |
-131992849, -131992849 |
NM_175445, BC057402 NM_175445, BC057402 |
215653 |
22 |
chromosome, centromeric region kinetochore skeletal system development ossification protein kinase activity protein binding nucleus nucleus nucleus nucleoplasm chromosome cytoplasm cytoplasm cytoplasm Golgi apparatus cytosol plasma membrane cell cycle signal transduction positive regulation of protein autophosphorylation protein-containing complex negative regulation of peptidyl-serine phosphorylation epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade regulation of apoptotic process positive regulation of apoptotic process regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein kinase activity positive regulation of protein kinase activity positive regulation of JNK cascade positive regulation of JNK cascade bone remodeling homeostasis of number of cells protein stabilization regulation of NIK/NF-kappaB signaling regulation of NIK/NF-kappaB signaling negative regulation of NIK/NF-kappaB signaling |
|
| TC0100000399.mm.2 |
Mars2 |
methionine-tRNA synthetase 2 (mitochondrial) |
1 |
55237176 |
NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 |
212679 |
20 |
nucleotide binding aminoacyl-tRNA ligase activity methionine-tRNA ligase activity methionine-tRNA ligase activity ATP binding mitochondrion mitochondrial matrix translation tRNA aminoacylation for protein translation methionyl-tRNA aminoacylation methionyl-tRNA aminoacylation ligase activity |
00450 00970 |
| TC0400000501.mm.2 |
Ncbp1 |
nuclear cap binding protein subunit 1 |
4 |
46138510 |
NM_001033201, BC138898 NM_001033201, BC138898 |
433702 |
29 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay spliceosomal complex assembly RNA cap binding RNA 7-methylguanosine cap binding RNA binding mRNA binding protein binding nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol mRNA cap binding complex mRNA cap binding complex nuclear cap binding complex nuclear cap binding complex 7-methylguanosine mRNA capping mRNA processing RNA catabolic process mRNA export from nucleus mRNA export from nucleus regulation of translation regulation of translational initiation RNA splicing RNA metabolic process positive regulation of cell growth gene silencing by RNA positive regulation of mRNA 3'-end processing RNA cap binding complex mRNA cis splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome regulation of mRNA processing mRNA transport pre-mRNA cleavage required for polyadenylation positive regulation of RNA binding ribonucleoprotein complex |
03013 03015 03040 |
| TC0500001853.mm.2 |
B3glct |
beta-3-glucosyltransferase |
5 |
149678229 |
NM_001081204 |
381694 |
19 |
cellular_component endoplasmic reticulum carbohydrate metabolic process fucose metabolic process biological_process acetylglucosaminyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups |
00514 |
| TC0900001005.mm.2 |
Fam214a |
family with sequence similarity 214, member A |
9 |
74952879, 74976110, 74953052 |
NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353 |
235493 |
15 |
molecular_function cellular_component biological_process |
|
| TC0100000471.mm.2 |
Abi2 |
abl interactor 2 |
1 |
60409618 |
NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 |
329165 |
33 |
cytoplasm cytosol cytoskeleton actin filament adherens junction adherens junction nervous system development learning or memory actin polymerization or depolymerization positive regulation of lamellipodium assembly dendrite development cell migration Rac protein signal transduction SH3 domain binding SH3 domain binding peptidyl-tyrosine phosphorylation lamellipodium lamellipodium cell junction dendrite SCAR complex small GTPase binding ubiquitin protein ligase binding filopodium tip signaling adaptor activity identical protein binding cell projection camera-type eye development dendritic spine zonula adherens assembly synapse regulation of dendritic spine morphogenesis proline-rich region binding lens fiber cell morphogenesis postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton organization postsynaptic actin cytoskeleton organization glutamatergic synapse glutamatergic synapse positive regulation of Arp2/3 complex-mediated actin nucleation |
04810 |
| MG-1-neg-10338901_st |
|
|
|
|
|
|
|
|
|
| TC1000000566.mm.2 |
Lrrc20 |
leucine rich repeat containing 20 |
10 |
61475832 |
NM_153542, BC036304 NM_153542, BC036304 |
216011 |
15 |
molecular_function cellular_component biological_process |
|
| TC0200002668.mm.2 |
Cass4 |
Cas scaffolding protein family member 4 |
2 |
172393643 |
NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 NM_001080820, NM_001276422, NM_001276423, BC117858, BC117859, BC129975, BC129976, NM_001033538 |
320664 |
13 |
cytoplasm cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway cell migration cell junction positive regulation of cell migration positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity actin filament reorganization positive regulation of substrate adhesion-dependent cell spreading protein tyrosine kinase binding |
|
| TC1400001931.mm.2 |
Wdhd1 |
WD repeat and HMG-box DNA binding protein 1 |
14 |
-47240943 |
NM_172598, BC063740 NM_172598, BC063740 |
218973 |
22 |
mitotic cell cycle chromosome, centromeric region DNA binding chromatin binding chromatin binding RNA binding protein binding nucleus nucleoplasm DNA-dependent DNA replication DNA repair RNA processing regulation of chromosome organization nuclear replication fork RNA polymerase binding heterochromatin maintenance |
|
| TC1400000347.mm.2 |
Ercc6 |
excision repair cross-complementing rodent repair deficiency, complementation group 6 |
14 |
32513520 |
NM_001081221, BC167234 NM_001081221, BC167234 |
319955 |
84 |
single strand break repair DNA damage checkpoint nucleotide binding response to superoxide positive regulation of defense response to virus by host DNA binding chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus DNA repair DNA repair DNA repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair base-excision repair pyrimidine dimer repair transcription elongation from RNA polymerase I promoter cellular response to DNA damage stimulus response to oxidative stress response to oxidative stress activation of JNKK activity activation of JUN kinase activity nervous system development protein C-terminus binding transcription elongation factor complex DNA-dependent ATPase activity DNA-dependent ATPase activity intrinsic apoptotic signaling pathway in response to DNA damage response to UV response to UV response to toxic substance response to X-ray response to UV-B response to gamma radiation positive regulation of gene expression nuclear body hydrolase activity neurogenesis neuron differentiation protein tyrosine kinase activator activity neuron projection development regulation of DNA-templated transcription, elongation positive regulation of DNA-templated transcription, elongation positive regulation of peptidyl-serine phosphorylation of STAT protein multicellular organism growth ATP-dependent chromatin remodeling sequence-specific DNA binding protein-containing complex binding photoreceptor cell maintenance positive regulation of DNA repair protein N-terminus binding positive regulation of transcription initiation from RNA polymerase II promoter positive regulation of transcription initiation from RNA polymerase II promoter RNA polymerase binding site of DNA damage double-strand break repair via classical nonhomologous end joining positive regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via nonhomologous end joining |
03420 |
| TC1000000312.mm.2 |
Hdac2 |
histone deacetylase 2 |
10 |
36974543 |
NM_008229, BC138517 NM_008229, BC138517 |
15182 |
299 |
histone deacetylase complex histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor binding chromatin binding histone deacetylase activity histone deacetylase activity histone deacetylase activity histone deacetylase activity protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork transcription regulator complex cytoplasm cytoplasm chromatin organization protein deacetylation transcription factor binding transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation epidermal cell differentiation positive regulation of epithelial to mesenchymal transition negative regulation of neuron projection development negative regulation of neuron projection development dendrite development histone deacetylation histone deacetylation Sin3 complex NuRD complex hydrolase activity transcription repressor complex deacetylase activity deacetylase activity enzyme binding enzyme binding hippocampus development neuron differentiation heat shock protein binding chromatin DNA binding NAD-dependent histone deacetylase activity (H3-K14 specific) positive regulation of interleukin-1 production positive regulation of tumor necrosis factor production circadian regulation of gene expression protein-containing complex protein deacetylase activity protein deacetylase activity histone deacetylase activity (H4-K16 specific) ESC/E(Z) complex Krueppel-associated box domain binding cellular response to trichostatin A odontogenesis of dentin-containing tooth positive regulation of tyrosine phosphorylation of STAT protein embryonic digit morphogenesis histone deacetylase binding negative regulation of apoptotic process negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding positive regulation of proteolysis negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II rhythmic process positive regulation of oligodendrocyte differentiation positive regulation of oligodendrocyte differentiation NF-kappaB binding positive regulation of DNA-binding transcription factor activity regulation of protein kinase B signaling cardiac muscle cell development negative regulation of cardiac muscle cell proliferation regulation of sarcomere organization hair follicle placode formation negative regulation of dendritic spine development eyelid development in camera-type eye fungiform papilla formation cellular response to hydrogen peroxide histone H3-K27 methylation heterochromatin maintenance histone H3 deacetylation histone H3 deacetylation histone H3 deacetylation histone H4 deacetylation histone H4 deacetylation negative regulation of canonical Wnt signaling pathway regulation of protein deacetylation RNA polymerase II transcription repressor complex positive regulation of male mating behavior negative regulation of pri-miRNA transcription by RNA polymerase II negative regulation of pri-miRNA transcription by RNA polymerase II promoter-specific chromatin binding positive regulation of signaling receptor activity negative regulation of peptidyl-lysine acetylation negative regulation of intrinsic apoptotic signaling pathway |
04110 04330 05016 05200 05220 |
| TC1300000626.mm.2 |
Simc1 |
SUMO-interacting motifs containing 1 |
13 |
54503804 |
NM_176987, BC167252 NM_176987, BC167252 |
319719 |
12 |
cytoplasm biological_process sarcomere peptidase inhibitor activity SUMO polymer binding SUMO polymer binding |
|
| TC0700003075.mm.2 |
E2f8 |
E2F transcription factor 8 |
7 |
-48866428, -48866428 |
NM_001013368, BC086675, E2F NM_001013368, BC086675, E2F NM_001013368, BC086675, E2F |
108961 |
43 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific placenta development sprouting angiogenesis sprouting angiogenesis DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleoplasm transcription regulator complex nucleolus cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle cell population proliferation negative regulation of cytokinesis positive regulation of DNA endoreduplication cell cycle comprising mitosis without cytokinesis identical protein binding positive regulation of transcription by RNA polymerase II trophoblast giant cell differentiation chorionic trophoblast cell differentiation hepatocyte differentiation RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding |
|
| TC1100000021.mm.2 |
Morc2a |
microrchidia 2A |
11 |
3649436, 3658671 |
NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243 |
74522 |
25 |
nucleotide binding magnesium ion binding heterochromatin chromatin binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytosol chromatin remodeling cellular response to DNA damage stimulus zinc ion binding nuclear matrix hydrolase activity ATPase activity histone binding protein homodimerization activity negative regulation of gene expression, epigenetic negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate metal ion binding positive regulation of DNA methylation-dependent heterochromatin assembly positive regulation of DNA methylation-dependent heterochromatin assembly |
|
| TC1200000348.mm.2 |
Etv1 |
ets variant 1 |
12 |
38783710, 38780081 |
NM_001163154, NM_007960, BC005645 NM_001163154, NM_007960, BC005645 NM_001163154, NM_007960, BC005645 |
14009 |
289 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II axon guidance muscle organ development mechanosensory behavior cell differentiation sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II peripheral nervous system neuron development sequence-specific double-stranded DNA binding |
|
| TC0700001906.mm.2 |
Tacc2 |
transforming, acidic coiled-coil containing protein 2 |
7 |
130577437, 130692617 |
NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856 |
57752 |
33 |
microtubule cytoskeleton organization microtubule cytoskeleton organization nucleus nucleoplasm cytoplasm cytosol cytoskeleton plasma membrane mitotic spindle organization cell population proliferation cell population proliferation protein domain specific binding cerebral cortex development cerebral cortex development neurogenesis interkinetic nuclear migration astral microtubule organization regulation of microtubule-based process nuclear hormone receptor binding |
|
| TC1000000191.mm.2 |
Slc18b1 |
solute carrier family 18, subfamily B, member 1 |
10 |
23796985 |
NM_183116 |
76306 |
17 |
membrane integral component of membrane transmembrane transporter activity |
|
| TC0100002963.mm.2 |
Tmem37 |
transmembrane protein 37 |
1 |
-120067376 |
NM_019432, BC024613 NM_019432, BC024613 |
170706 |
20 |
voltage-gated ion channel activity calcium channel activity ion transport calcium ion transport membrane integral component of membrane regulation of ion transmembrane transport calcium ion transmembrane transport |
|
| TC0900003168.mm.2 |
Crtap |
cartilage associated protein |
9 |
-114375130 |
NM_019922, BC049890 NM_019922, BC049890 |
56693 |
28 |
collagen binding extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum spermatogenesis peptidyl-proline hydroxylation to 3-hydroxy-L-proline peptidyl-proline hydroxylation to 3-hydroxy-L-proline collagen fibril organization protein stabilization negative regulation of post-translational protein modification |
|
| TC0600000127.mm.2 |
Cav2 |
caveolin 2 |
6 |
17281184, 17281184 |
NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095 |
12390 |
68 |
SNARE binding negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation acrosomal membrane caveolar macromolecular signaling complex protein binding nucleus nuclear envelope nuclear inner membrane cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus lipid droplet cytosol plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola caveola caveola focal adhesion focal adhesion focal adhesion endocytosis vesicle fusion vesicle fusion mitochondrion organization endoplasmic reticulum organization chemical synaptic transmission negative regulation of cell population proliferation insulin receptor signaling pathway insulin receptor signaling pathway cell surface membrane membrane vesicle organization receptor-mediated endocytosis of virus by host cell protein kinase binding protein kinase binding protein kinase binding syntaxin binding transport vesicle cell differentiation negative regulation of transforming growth factor beta receptor signaling pathway protein-macromolecule adaptor activity extrinsic component of cytoplasmic side of plasma membrane extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cytoplasmic vesicle mitogen-activated protein kinase kinase kinase binding D1 dopamine receptor binding D1 dopamine receptor binding protein-containing complex protein-containing complex sarcolemma protein homodimerization activity positive regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation by host of viral release from host cell positive regulation by host of viral process membrane raft protein heterodimerization activity vesicle docking vesicle docking perinuclear region of cytoplasm perinuclear region of cytoplasm perinuclear region of cytoplasm skeletal muscle fiber development positive regulation of peptidyl-tyrosine phosphorylation phosphoprotein binding regulation of cytosolic calcium ion concentration molecular adaptor activity molecular adaptor activity positive regulation of dopamine receptor signaling pathway positive regulation of dopamine receptor signaling pathway caveola assembly caveola assembly caveola assembly basement membrane organization scaffold protein binding positive regulation of protein localization to nucleus |
04144 04510 05100 |
| TC0X00001674.mm.2 |
Fancb |
Fanconi anemia, complementation group B |
X |
164980591 |
NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151 |
237211 |
17 |
molecular_function nucleus DNA repair cellular response to DNA damage stimulus cellular response to drug cellular response to drug interstrand cross-link repair Fanconi anaemia nuclear complex Fanconi anaemia nuclear complex cellular response to camptothecin positive regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair via homologous recombination replication-born double-strand break repair via sister chromatid exchange replication-born double-strand break repair via sister chromatid exchange negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC1600000440.mm.2 |
Tm4sf19 |
transmembrane 4 L six family member 19 |
16 |
32400505 |
NM_001160402, BC147727, BC147729 NM_001160402, BC147727, BC147729 NM_001160402, BC147727, BC147729 |
277203 |
4 |
molecular_function biological_process integral component of membrane |
|
| TC0600001027.mm.2 |
Rpn1 |
ribophorin I |
6 |
88084472 |
NM_133933, BC016080 NM_133933, BC016080 |
103963 |
35 |
dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum endoplasmic reticulum membrane rough endoplasmic reticulum rough endoplasmic reticulum cytosol protein glycosylation protein N-linked glycosylation oligosaccharyltransferase complex oligosaccharyltransferase complex membrane integral component of membrane protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine |
00510 01100 04141 |
| TC1400002387.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0900002367.mm.2 |
1700017B05Rik |
RIKEN cDNA 1700017B05 gene |
9 |
-57252321 |
NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965 NM_028820, BC118527, BC150963, BC150965 |
74211 |
16 |
molecular_function cytosol biological_process |
|
| TC0300001478.mm.2 |
Znhit6 |
zinc finger, HIT type 6 |
3 |
145576215, 145576207 |
NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 |
229937 |
13 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) box C/D snoRNP assembly box C/D snoRNP assembly TFIID-class transcription factor complex binding nucleus enzyme binding ribosome biogenesis identical protein binding metal ion binding snoRNA localization snoRNA localization ATPase binding protein complex oligomerization pre-snoRNP complex pre-snoRNP complex |
|
| TC0900002047.mm.2 |
Ccdc15 |
coiled-coil domain containing 15 |
9 |
-37267463 |
NM_001081429 |
245902 |
12 |
molecular_function centrosome centrosome biological_process |
|
| TC1200002092.mm.2 |
Acyp1 |
acylphosphatase 1, erythrocyte (common) type |
12 |
-85272397, -85278893, -85272397 |
NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783 NM_025421, BC061088, BC116781, BC116783 |
66204 |
13 |
acylphosphatase activity biological_process hydrolase activity |
00620 |
| MG-1-neg-10341270_st |
|
|
|
|
|
|
|
|
|
| TC0900002489.mm.2 |
Zwilch |
zwilch kinetochore protein |
9 |
-64137143 |
NM_026507, BC027435 NM_026507, BC027435 |
68014 |
18 |
chromosome, centromeric region kinetochore molecular_function chromosome cell cycle mitotic cell cycle checkpoint protein localization to kinetochore cell division signal transduction involved in mitotic cell cycle checkpoint RZZ complex |
|
| TC1300002766.mm.2 |
Nsun2 |
NOL1/NOP2/Sun domain family member 2 |
13 |
69612015 |
NM_145354, BC013625 NM_145354, BC013625 |
28114 |
49 |
tRNA binding RNA methylation in utero embryonic development RNA binding extracellular region nucleus nucleolus cytoplasm cytoplasm mitochondrion cytoskeleton cell cycle spermatogenesis spermatid development tRNA processing methyltransferase activity regulation of mRNA export from nucleus tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity transferase activity cell differentiation tRNA methylation tRNA methylation tRNA methylation tRNA methylation methylation meiotic cell cycle checkpoint chromatoid body tRNA stabilization hair follicle maturation cell division mRNA (cytidine-5-)-methyltransferase activity mRNA (cytidine-5-)-methyltransferase activity extracellular exosome mRNA methylation mRNA methylation regulation of stem cell differentiation |
|
| TC0200001546.mm.2 |
Lmo2 |
LIM domain only 2 |
2 |
103969556, 103970286, 103957994 |
NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 NM_001142335, NM_001142336, NM_001142337, NM_008505, BC057880 |
16909 |
110 |
RNA polymerase II activating transcription factor binding transcription coregulator binding DNA binding chromatin binding transcription coactivator activity protein binding nucleus transcription regulator complex transcription factor binding protein-containing complex embryonic hemopoiesis identical protein binding bHLH transcription factor binding negative regulation of erythrocyte differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cellular response to thyroid hormone stimulus |
|
| MG-1-pos-10338865_st |
|
|
|
|
|
|
|
|
|
| TC1500001653.mm.2 |
Tmem71 |
transmembrane protein 71 |
15 |
-66526211 |
NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824 |
213068 |
13 |
molecular_function mitochondrion biological_process membrane integral component of membrane |
|
| TC1900001619.mm.2 |
Pcgf6 |
polycomb group ring finger 6 |
19 |
-47033616 |
NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460 |
71041 |
35 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II protein binding nucleus nucleus regulation of transcription by RNA polymerase II protein domain specific binding PcG protein complex PcG protein complex PRC1 complex PRC1 complex histone H2A-K119 monoubiquitination histone H2A-K119 monoubiquitination negative regulation of transcription, DNA-templated metal ion binding |
|
| TC1400002260.mm.2 |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
14 |
-65819026 |
NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275 |
71988 |
35 |
chromatin XY body hematopoietic progenitor cell differentiation lysine N-acetyltransferase activity, acting on acetyl phosphate as donor nucleus nucleoplasm chromosome pericentric heterochromatin Golgi apparatus regulation of DNA replication regulation of DNA replication double-strand break repair cell cycle chromosome segregation sister chromatid cohesion chromocenter acetyltransferase activity transferase activity transferase activity, transferring acyl groups cell junction post-translational protein acetylation post-translational protein acetylation site of double-strand break metal ion binding protein localization to chromatin |
|
| TC1400000862.mm.2 |
Arl11 |
ADP-ribosylation factor-like 11 |
14 |
61309752 |
NM_177337, BC064093 NM_177337, BC064093 |
219144 |
13 |
nucleotide binding hematopoietic progenitor cell differentiation GTP binding cytoplasm plasma membrane intracellular protein transport vesicle-mediated transport |
|
| TC1100002740.mm.2 |
Rad50 |
RAD50 double strand break repair protein |
11 |
-53649518 |
NM_009012, BC168398 NM_009012, BC168398 |
19360 |
68 |
single-stranded DNA endodeoxyribonuclease activity regulation of mitotic recombination nucleotide binding telomere maintenance via recombination telomere maintenance chromosome, telomeric region chromatin condensed nuclear chromosome condensed nuclear chromosome DNA binding DNA helicase activity double-stranded DNA binding double-stranded telomeric DNA binding ATP binding nucleus nucleoplasm chromosome DNA repair double-strand break repair double-strand break repair DNA recombination cellular response to DNA damage stimulus telomere maintenance via telomerase telomere maintenance via telomerase cell cycle regulation of mitotic cell cycle 3'-5' exonuclease activity inclusion body hydrolase activity ATPase activity protein-macromolecule adaptor activity Mre11 complex Mre11 complex telomeric 3' overhang formation positive regulation of protein autophosphorylation positive regulation of telomere maintenance DNA duplex unwinding DNA duplex unwinding positive regulation of kinase activity site of double-strand break identical protein binding single-stranded telomeric DNA binding protein-containing complex binding pronucleus negative regulation of viral entry into host cell metal ion binding perinuclear region of cytoplasm chromosome organization meiotic cell cycle G-quadruplex DNA binding chromosome organization involved in meiotic cell cycle chromosome organization involved in meiotic cell cycle nucleic acid phosphodiester bond hydrolysis negative regulation of telomere capping |
03440 03450 |
| TC0100001853.mm.2 |
Ints7 |
integrator complex subunit 7 |
1 |
191575635 |
NM_178632, BC054120 NM_178632, BC054120 |
77065 |
25 |
DNA damage checkpoint molecular_function nucleus chromosome cytoplasm cellular response to DNA damage stimulus snRNA processing nuclear body integrator complex integrator complex snRNA 3'-end processing cellular response to ionizing radiation |
|
| TC0700003608.mm.2 |
Cpeb1 |
cytoplasmic polyadenylation element binding protein 1 |
7 |
-81347025, -81347025 |
NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 |
12877 |
64 |
translation repressor activity, mRNA regulatory element binding translation repressor activity, mRNA regulatory element binding nucleic acid binding RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm centrosome cytosol mRNA processing regulation of translation synaptonemal complex assembly translation factor activity, RNA binding negative regulation of cell population proliferation positive regulation of neuron projection development postsynaptic density membrane negative regulation of translation cell junction positive regulation of cell migration growth cone cellular response to insulin stimulus mRNA 3'-UTR AU-rich region binding neuron projection ribosome binding neuronal cell body translation regulator activity synapse positive regulation of translation metal ion binding regulation of neuronal synaptic plasticity perinuclear region of cytoplasm mRNA transport positive regulation of nitric-oxide synthase biosynthetic process cellular response to amino acid stimulus cellular response to hypoxia cellular response to hypoxia meiotic spindle positive regulation of mRNA polyadenylation messenger ribonucleoprotein complex negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation |
04114 04320 04914 |
| TC0500000050.mm.2 |
Abcb1a |
ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
5 |
8567090 |
NM_011076 |
18671 |
275 |
G2/M transition of mitotic cell cycle nucleotide binding ATP binding nucleoplasm plasma membrane plasma membrane plasma membrane ABC-type xenobiotic transporter activity ABC-type xenobiotic transporter activity hormone transport cell surface efflux transmembrane transporter activity efflux transmembrane transporter activity membrane integral component of membrane apical plasma membrane apical plasma membrane ATPase activity ATPase activity transmembrane transporter activity brush border membrane ubiquitin protein ligase binding carbohydrate export maintenance of blood-brain barrier ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity xenobiotic transmembrane transporter activity xenobiotic transmembrane transporter activity daunorubicin transport apical part of cell phospholipid translocation phospholipid translocation phospholipid translocation intercellular canaliculus terpenoid transport carboxylic acid transmembrane transporter activity regulation of response to osmotic stress intestinal absorption transmembrane transport negative regulation of cell death establishment of blood-brain barrier transepithelial transport stem cell proliferation phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity phosphatidylethanolamine flippase activity phosphatidylethanolamine flippase activity ceramide floppase activity ceramide floppase activity ceramide floppase activity ceramide translocation ceramide translocation ceramide translocation export across plasma membrane export across plasma membrane floppase activity floppase activity positive regulation of anion channel activity protein localization to bicellular tight junction positive regulation of establishment of Sertoli cell barrier regulation of intestinal absorption carboxylic acid transmembrane transport xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic transport across blood-brain barrier xenobiotic transport across blood-brain barrier establishment of blood-retinal barrier positive regulation of response to drug regulation of chloride transport |
02010 04976 |
| TC0200002043.mm.2 |
Mcm8 |
minichromosome maintenance 8 homologous recombination repair factor |
2 |
132816140 |
NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070 |
66634 |
19 |
nucleotide binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA binding chromatin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleoplasm chromosome cytosol DNA replication DNA replication initiation DNA repair cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle female gamete generation hydrolase activity enzyme binding MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding recombinational interstrand cross-link repair MCM complex male gamete generation protein stabilization protein localization to chromatin MCM8-MCM9 complex MCM8-MCM9 complex |
|
| TC0300002580.mm.2 |
Wdr3 |
WD repeat domain 3 |
3 |
-100138179 |
NM_175552, BC063100 NM_175552, BC063100 |
269470 |
20 |
nucleus nucleoplasm nucleolus maturation of SSU-rRNA snoRNA binding nuclear membrane small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC1300001374.mm.2 |
Net1 |
neuroepithelial cell transforming gene 1 |
13 |
-3882017, -3882017 |
NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699 |
56349 |
33 |
guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm plasma membrane small GTPase binding regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction intracellular signal transduction positive regulation of apoptotic process positive regulation of GTPase activity myoblast migration cellular response to hydrogen peroxide cellular response to ionizing radiation positive regulation of substrate adhesion-dependent cell spreading |
|
| TC1300000781.mm.2 |
Cdk20 |
cyclin-dependent kinase 20 |
13 |
64432552 |
NM_053180, BC031907 NM_053180, BC031907 |
105278 |
24 |
nucleotide binding neural tube closure protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytoplasm cilium protein phosphorylation cell cycle multicellular organism development kinase activity phosphorylation transferase activity floor plate formation embryonic camera-type eye development cell projection embryonic skeletal system development cell division roof of mouth development positive regulation of cardiac muscle cell proliferation protein localization to cilium protein threonine kinase activity regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning regulation of protein maturation embryonic brain development |
|
| TC1700001357.mm.2 |
Tfb1m |
transcription factor B1, mitochondrial |
17 |
-3519250 |
NM_146074, BC032930 NM_146074, BC032930 |
224481 |
26 |
rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity DNA binding RNA binding mitochondrion mitochondrial matrix rRNA processing transcription initiation from mitochondrial promoter methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation methylation mitochondrial transcription factor activity mitochondrial nucleoid |
|
| TC0100003877.mm.2 |
Poglut2 |
protein O-glucosyltransferase 2 |
1 |
-44106545 |
NM_023645, BC023141 NM_023645, BC023141 |
72050 |
23 |
nucleoplasm endoplasmic reticulum endoplasmic reticulum lumen cytosol endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity |
|
| TC1200000255.mm.2 |
Tmem18 |
transmembrane protein 18 |
12 |
30584442 |
NM_172049, BC024093 NM_172049, BC024093 |
211986 |
14 |
molecular_function DNA binding nucleus cytoplasm membrane integral component of membrane cell migration |
|
| TC0200002442.mm.2 |
Fam83d |
family with sequence similarity 83, member D |
2 |
158768098 |
NM_027975, BC068129 NM_027975, BC068129 |
71878 |
16 |
epithelial to mesenchymal transition cytoplasm spindle cytosol cytosol cytoskeleton cell cycle signal transduction microtubule binding cell population proliferation microtubule cytoskeleton cell migration kinesin binding protein kinase binding protein kinase binding regulation of TOR signaling regulation of TOR signaling regulation of protein catabolic process intercellular bridge cell division metaphase plate congression regulation of ERK1 and ERK2 cascade regulation of ERK1 and ERK2 cascade mitotic spindle mitotic spindle pole mitotic spindle pole protein localization to mitotic spindle protein localization to mitotic spindle positive regulation of cell cycle G1/S phase transition positive regulation of cell cycle G1/S phase transition |
|
| TC1200000825.mm.2 |
Ylpm1 |
YLP motif containing 1 |
12 |
84996320 |
NM_178363 |
56531 |
25 |
negative regulation of transcription by RNA polymerase II DNA-binding transcription repressor activity, RNA polymerase II-specific nucleus nucleus nucleus nucleoplasm cytosol nuclear speck regulation of telomere maintenance regulation of telomere maintenance |
|
| TC0400004151.mm.2 |
Atad3a |
ATPase family, AAA domain containing 3A |
4 |
-155740639 |
NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 |
108888 |
43 |
nucleotide binding regulation of cell growth protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrion organization zinc ion binding membrane integral component of membrane mitochondrial nucleoid identical protein binding negative regulation of apoptotic process antiviral innate immune response |
|
| TC1400000501.mm.2 |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
14 |
46760540 |
NM_028222, BC049694 NM_028222, BC049694 |
72391 |
17 |
phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding cytoplasm cytosol cellular response to DNA damage stimulus cell cycle cell cycle arrest cell cycle arrest dephosphorylation hydrolase activity phosphatase activity perinuclear region of cytoplasm |
|
| TC0300002906.mm.2 |
Larp7 |
La ribonucleoprotein domain family, member 7 |
3 |
-127536713 |
NM_138593, BC153029 NM_138593, BC153029 |
28036 |
33 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II box C/D RNA 3'-end processing box C/D RNA 3'-end processing nucleic acid binding RNA binding nucleus nucleus nucleoplasm cytosol RNA processing mRNA processing spermatogenesis RNA splicing U6 snRNA binding U6 snRNA binding cell differentiation negative regulation of viral transcription negative regulation of chromatin binding germ cell proliferation regulation of mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome 7SK snRNA binding 7SK snRNP positive regulation of G1/S transition of mitotic cell cycle positive regulation of protein localization to Cajal body positive regulation of snRNA transcription by RNA polymerase II U6 2'-O-snRNA methylation U6 2'-O-snRNA methylation ribonucleoprotein complex |
|
| TC0500001066.mm.2 |
Cdc7 |
cell division cycle 7 (S. cerevisiae) |
5 |
106964321, 106964560 |
NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 |
12545 |
32 |
nucleotide binding double-strand break repair via break-induced replication protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm protein phosphorylation cell cycle positive regulation of cell population proliferation positive regulation of nuclear cell cycle DNA replication positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell cycle phase transition intercellular bridge metal ion binding cell division mitotic spindle |
04110 |
| TC0300000807.mm.2 |
S100a4 |
S100 calcium binding protein A4 |
3 |
90603769 |
NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100 NM_011311, BC051214, BC094635, S100 |
20198 |
169 |
actin binding calcium ion binding calcium ion binding calcium ion binding protein binding nucleus nucleus identical protein binding identical protein binding neuron projection positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling metal ion binding transition metal ion binding calcium-dependent protein binding calcium-dependent protein binding perinuclear region of cytoplasm perinuclear region of cytoplasm RAGE receptor binding RAGE receptor binding |
|
| TC1700001805.mm.2 |
Glo1 |
glyoxalase 1 |
17 |
-30592861 |
NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 |
109801 |
99 |
lactoylglutathione lyase activity lactoylglutathione lyase activity nucleoplasm cytosol plasma membrane carbohydrate metabolic process regulation of transcription by RNA polymerase II glutathione metabolic process zinc ion binding zinc ion binding methylglyoxal metabolic process lyase activity methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione osteoclast differentiation negative regulation of apoptotic process metal ion binding |
00620 |
| TC0500000852.mm.2 |
Mthfd2l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
5 |
90931195 |
NM_026788 |
665563 |
17 |
histidine biosynthetic process catalytic activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity mitochondrion mitochondrial inner membrane mitochondrial matrix purine nucleotide biosynthetic process one-carbon metabolic process metabolic process cellular amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate metabolic process membrane oxidoreductase activity hydrolase activity tetrahydrofolate interconversion tetrahydrofolate interconversion |
00670 01100 |
| TC0100001548.mm.2 |
Tmco1 |
transmembrane and coiled-coil domains 1 |
1 |
167308669 |
NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 |
68944 |
31 |
calcium channel activity calcium channel activity cytoplasm endoplasmic reticulum endoplasmic reticulum Golgi apparatus ion transport calcium ion transport cellular calcium ion homeostasis ER overload response membrane integral component of membrane integral component of endoplasmic reticulum membrane endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis calcium ion transmembrane transport calcium ion transmembrane transport |
|
| TC0200002579.mm.2 |
Ddx27 |
DEAD box helicase 27 |
2 |
167015312 |
NM_153065, BC011321 NM_153065, BC011321 |
228889 |
30 |
nucleotide binding nucleic acid binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus rRNA processing hydrolase activity ribosome biogenesis |
|
| TC1900000763.mm.2 |
Pdcd4 |
programmed cell death 4 |
19 |
53903350, 53892230 |
NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 |
18569 |
88 |
RNA binding protein binding nucleus nucleus cytoplasm cytosol cytosol apoptotic process cell aging BMP signaling pathway positive regulation of smooth muscle cell apoptotic process negative regulation of apoptotic process negative regulation of transcription, DNA-templated positive regulation of inflammatory response regulation of protein metabolic process epithelial to mesenchymal transition involved in cardiac fibroblast development cellular response to lipopolysaccharide negative regulation of cytokine production involved in inflammatory response positive regulation of NIK/NF-kappaB signaling negative regulation of vascular associated smooth muscle cell proliferation negative regulation of myofibroblast differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of vascular associated smooth muscle cell apoptotic process positive regulation of endothelial cell apoptotic process |
|
| TC1000000744.mm.2 |
Lss |
lanosterol synthase |
10 |
76531604 |
NM_146006, BC029082 NM_146006, BC029082 |
16987 |
36 |
lanosterol synthase activity lanosterol synthase activity endoplasmic reticulum endoplasmic reticulum membrane lipid droplet lipid droplet lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process membrane sterol metabolic process isomerase activity intramolecular transferase activity regulation of protein stability intracellular membrane-bounded organelle |
00100 01100 |
| TC0600002656.mm.2 |
Arhgap25 |
Rho GTPase activating protein 25 |
6 |
-87458544, -87458544 |
NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 NM_001037727, NM_001286610, NM_175476, NR_104483, BC138751, BC138752 |
232201 |
21 |
phagocytic cup phagocytic cup GTPase activator activity phagocytosis, engulfment phagocytosis, engulfment actin filament organization actin filament organization signal transduction negative regulation of small GTPase mediated signal transduction negative regulation of small GTPase mediated signal transduction activation of GTPase activity |
|
| TC1700002771.mm.2 |
Nme3 |
NME/NM23 nucleoside diphosphate kinase 3 |
17 |
24896499 |
NM_019730, BC028503, NME/NM23 NM_019730, BC028503, NME/NM23 NM_019730, BC028503, NME/NM23 |
79059 |
24 |
nucleotide binding nucleoside diphosphate kinase activity ATP binding mitochondrion GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process kinase activity phosphorylation transferase activity metal ion binding |
00230 00240 01100 |
| TC1900001510.mm.2 |
Arhgap19 |
Rho GTPase activating protein 19 |
19 |
-41766587 |
NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 |
71085 |
22 |
GTPase activator activity cytoplasm plasma membrane signal transduction intracellular membrane-bounded organelle regulation of small GTPase mediated signal transduction |
|
| TC0X00000652.mm.2 |
Hmgb3 |
high mobility group box 3 |
X |
71555916 |
NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 |
15354 |
39 |
immune system process DNA binding RNA binding nucleus chromosome cytoplasm regulation of transcription by RNA polymerase II DNA binding, bending innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation |
|
| MG-1-neg-10339902_st |
|
|
|
|
|
|
|
|
|
| TC0500002458.mm.2 |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
5 |
-62602445 |
NM_178407 |
212285 |
18 |
GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm signal transduction positive regulation of GTPase activity metal ion binding |
04144 |
| TC0200005331.mm.2 |
|
|
|
|
XR_140551 |
|
|
|
|
| TC1800000344.mm.2 |
Wdr55 |
WD repeat domain 55 |
18 |
36760221 |
NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934 |
67936 |
17 |
molecular_function nucleus nucleoplasm nucleolus nucleolus cytoplasm rRNA processing rRNA processing |
|
| TC0100000267.mm.2 |
Lipt1 |
lipoyltransferase 1 |
1 |
37872218, 37872349, 37871737 |
NM_001037918, BC019519 NM_001037918, BC019519 |
623661 |
16 |
cytoplasm mitochondrion mitochondrion cellular protein modification process protein lipoylation transferase activity transferase activity, transferring acyl groups lipoyltransferase activity |
00785 01100 |
| TC0800000968.mm.2 |
Syce2 |
synaptonemal complex central element protein 2 |
8 |
84872110, 84872257 |
NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 |
71846 |
31 |
synaptonemal complex central element central element protein binding nucleus nucleoplasm nucleoplasm chromosome cell cycle synaptonemal complex assembly cell division meiotic cell cycle |
|
| TC1200001832.mm.2 |
Fkbp3 |
FK506 binding protein 3 |
12 |
-65062431 |
NM_013902, BC002122, FK506 NM_013902, BC002122, FK506 NM_013902, BC002122, FK506 |
30795 |
31 |
peptidyl-prolyl cis-trans isomerase activity protein binding nucleus isomerase activity |
|
| TC0700004326.mm.2 |
Zfp764 |
zinc finger protein 764 |
7 |
-127403667 |
NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397 |
233893 |
16 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| TC1100002297.mm.2 |
Cep68 |
centrosomal protein 68 |
11 |
-20227036 |
NM_172260, BC027174 NM_172260, BC027174 |
216543 |
20 |
nucleoplasm cytoplasm centrosome cytosol cytoskeleton centrosome cycle centriole-centriole cohesion protein kinase binding protein domain specific binding cell junction protein localization to organelle centriolar satellite |
|
| TC0100000829.mm.2 |
Dgkd |
diacylglycerol kinase, delta |
1 |
87853286 |
NM_177646 |
227333 |
35 |
nucleotide binding NAD+ kinase activity diacylglycerol kinase activity diacylglycerol kinase activity diacylglycerol kinase activity ATP binding cytoplasm cytosol plasma membrane clathrin-coated pit phosphatidic acid biosynthetic process endocytosis signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway response to organic substance protein transport membrane kinase activity phosphorylation transferase activity kinase binding cytoplasmic vesicle intracellular signal transduction identical protein binding protein homodimerization activity positive regulation of epidermal growth factor receptor signaling pathway diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding protein heterodimerization activity negative regulation of protein kinase C signaling positive regulation of clathrin-dependent endocytosis |
00561 00564 01100 04070 |
| TC0400002613.mm.2 |
Alg2 |
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) |
4 |
-47469832 |
NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411 |
56737 |
22 |
alpha-1,3-mannosyltransferase activity alpha-1,3-mannosyltransferase activity GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity nucleus cytoplasm cytosol protein glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process actin cytoskeleton membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein glycosylation in endoplasmic reticulum protein glycosylation in endoplasmic reticulum protein heterodimerization activity protein N-terminus binding calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity |
00510 01100 |
| TC1600000138.mm.2 |
Snx29 |
sorting nexin 29 |
16 |
11322903, 11405647 |
NM_028964 |
74478 |
15 |
molecular_function biological_process phosphatidylinositol binding |
|
| TC1300001642.mm.2 |
H3c3 |
H3 clustered histone 3 |
13 |
-23745041 |
NM_175653, BC120800, BC120802 NM_175653, BC120800, BC120802 NM_175653, BC120800, BC120802 |
319148 |
7 |
nucleosome nucleus nucleoplasm nucleosome assembly |
05322 |
| TC1400000910.mm.2 |
Pinx1 |
PIN2/TERF1 interacting, telomerase inhibitor 1 |
14 |
63860311 |
NM_028228, BC115636 NM_028228, BC115636 |
72400 |
17 |
nuclear chromosome chromosome, centromeric region kinetochore chromosome, telomeric region nucleic acid binding nucleus nucleoplasm chromosome nucleolus mitochondrion spindle telomere maintenance via telomerase mitotic metaphase plate congression telomerase inhibitor activity negative regulation of G2/M transition of mitotic cell cycle negative regulation of protein ubiquitination regulation of protein stability negative regulation of telomere maintenance via telomerase protein-containing complex binding negative regulation of telomerase activity telomerase RNA binding protein localization to chromosome, telomeric region protein localization to nucleolus positive regulation of telomeric DNA binding positive regulation of protein localization to nucleolus |
|
| TC1100003410.mm.2 |
Aatf |
apoptosis antagonizing transcription factor |
11 |
-84422855 |
NM_019816, BC025080 NM_019816, BC025080 |
56321 |
42 |
protein binding nucleus nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm Golgi apparatus cytosol regulation of transcription by RNA polymerase II cell adhesion regulation of mitotic cell cycle protein kinase binding negative regulation of superoxide anion generation embryonic cleavage ribosome biogenesis negative regulation of amyloid precursor protein biosynthetic process negative regulation of apoptotic process leucine zipper domain binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II tau protein binding negative regulation of reactive oxygen species metabolic process negative regulation of apoptotic signaling pathway |
|
| MG-1-pos-10338128_st |
|
|
|
|
|
|
|
|
|
| TC0100002899.mm.2 |
Kdsr |
3-ketodihydrosphingosine reductase |
1 |
-106720409, -106731201 |
NM_027534, BC023820 NM_027534, BC023820 |
70750 |
23 |
endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process sphingolipid metabolic process 3-keto-sphinganine metabolic process 3-keto-sphinganine metabolic process membrane integral component of membrane oxidoreductase activity sphingolipid biosynthetic process sphingolipid biosynthetic process 3-dehydrosphinganine reductase activity 3-dehydrosphinganine reductase activity |
00600 01100 |
| TC0700002924.mm.2 |
|
|
|
|
XR_105097 |
|
|
|
|
| TC0600002917.mm.2 |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
6 |
-113334123 |
NM_133926, BC014825 NM_133926, BC014825 |
52163 |
49 |
nucleotide binding catalytic activity protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calmodulin-dependent protein kinase activity protein binding calmodulin binding ATP binding intracellular anatomical structure nucleus cytoplasm protein phosphorylation protein phosphorylation protein phosphorylation nucleocytoplasmic transport nucleocytoplasmic transport cell cycle signal transduction multicellular organism development nervous system development metabolic process positive regulation of neuron projection development postsynaptic density kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell differentiation negative regulation of protein binding regulation of protein localization positive regulation of peptidyl-serine phosphorylation regulation of protein binding positive regulation of transcription by RNA polymerase II positive regulation of protein export from nucleus positive regulation of protein export from nucleus regulation of synapse organization regulation of muscle cell differentiation positive regulation of muscle cell differentiation positive regulation of synapse structural plasticity positive regulation of syncytium formation by plasma membrane fusion positive regulation of dendritic spine development positive regulation of protein serine/threonine kinase activity glutamatergic synapse positive regulation of protein acetylation |
|
| TC1600001050.mm.2 |
Chaf1b |
chromatin assembly factor 1, subunit B (p60) |
16 |
93883900 |
NM_028083, BC013532 NM_028083, BC013532 |
110749 |
29 |
chromatin protein binding nucleus nucleoplasm cytoplasm DNA replication DNA repair nucleosome assembly DNA replication-dependent nucleosome assembly cellular response to DNA damage stimulus cell cycle chromatin assembly protein-containing complex CAF-1 complex CAF-1 complex |
|
| TC0X00002648.mm.2 |
Maged1 |
MAGE family member D1 |
X |
-94535473 |
NM_019791, BC016438, BC031461 NM_019791, BC016438, BC031461 NM_019791, BC016438, BC031461 |
94275 |
69 |
chromatin transcription coactivator activity protein binding nucleus cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II membrane circadian regulation of gene expression protein-containing complex regulation of circadian rhythm identical protein binding regulation of apoptotic process positive regulation of MAP kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated rhythmic process negative regulation of epithelial cell proliferation positive regulation of branching involved in ureteric bud morphogenesis positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway |
04722 |
| TC0200002157.mm.2 |
Slc24a3 |
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
2 |
145242610, 145167774 |
NM_053195, BC017615 NM_053195, BC017615 |
94249 |
13 |
calcium channel activity plasma membrane plasma membrane integral component of plasma membrane ion transport cation transport potassium ion transport sodium ion transport calcium ion transport cellular calcium ion homeostasis cellular calcium ion homeostasis cellular calcium ion homeostasis cellular calcium ion homeostasis calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity positive regulation of gene expression negative regulation of gene expression symporter activity antiporter activity membrane integral component of membrane bone mineralization sodium ion transmembrane transport transmembrane transport calcium ion transmembrane transport calcium ion transmembrane transport potassium ion transmembrane transport cell periphery cell periphery |
|
| TC1200002002.mm.2 |
Erh |
ERH mRNA splicing and mitosis factor |
12 |
-80634020 |
NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 |
13877 |
34 |
osteoblast differentiation nucleus methyl-CpG binding membrane midbody methylosome |
|
| MG-1-neg-10343507_st |
|
|
|
|
|
|
|
|
|
| TC0400002709.mm.2 |
Tmem245 |
transmembrane protein 245 |
4 |
-56876013, -56876012 |
NM_175518 |
242474 |
16 |
membrane integral component of membrane |
|
| TC1400001152.mm.2 |
Bora |
bora, aurora kinase A activator |
14 |
99046376 |
NM_175265, BC052183 NM_175265, BC052183 |
77744 |
19 |
nucleus cytoplasm cell cycle regulation of mitotic nuclear division regulation of mitotic nuclear division protein kinase binding protein kinase binding activation of protein kinase activity regulation of protein localization cell division regulation of mitotic spindle organization regulation of mitotic spindle organization meiotic spindle |
|
| TC0400001477.mm.2 |
Sfpq |
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) |
4 |
127021300, 127021300 |
NM_023603, NR_045010, BC089305 NM_023603, NR_045010, BC089305 NM_023603, NR_045010, BC089305 |
71514 |
84 |
negative regulation of transcription by RNA polymerase II alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome double-strand break repair via homologous recombination chromatin transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding activation of innate immune response immune system process nucleic acid binding DNA binding chromatin binding RNA binding protein binding nucleus nucleus nucleoplasm cytoplasm DNA repair regulation of transcription, DNA-templated mRNA processing cellular response to DNA damage stimulus RNA splicing nuclear matrix paraspeckles paraspeckles regulation of circadian rhythm negative regulation of circadian rhythm protein homodimerization activity histone deacetylase binding innate immune response positive regulation of sister chromatid cohesion negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II rhythmic process chromosome organization regulation of cell cycle histone H3 deacetylation RNA polymerase II transcription regulator complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
|
| TC0200000391.mm.2 |
Zmynd19 |
zinc finger, MYND domain containing 19 |
2 |
24949776, 24950157 |
NM_026021, BC027321 NM_026021, BC027321 |
67187 |
26 |
molecular_function cytoplasm plasma membrane biological_process membrane synapse metal ion binding |
|
| TC1100004000.mm.2 |
Abca9 |
ATP-binding cassette, sub-family A (ABC1), member 9 |
11 |
-110100821 |
NM_147220 |
217262 |
15 |
nucleotide binding lipid transporter activity ATP binding mitochondrion lipid transport membrane integral component of membrane ATPase activity ATPase-coupled transmembrane transporter activity intracellular membrane-bounded organelle |
02010 |
| TC0X00002269.mm.2 |
Arhgef6 |
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
X |
-57231484, -57231484 |
NM_152801, BC156697 NM_152801, BC156697 |
73341 |
35 |
guanyl-nucleotide exchange factor activity protein binding cell-cell junction lamellipodium lamellipodium assembly regulation of Rho protein signal transduction intracellular signal transduction cell projection |
04810 05212 |
| TC1900000814.mm.2 |
Trub1 |
TruB pseudouridine (psi) synthase family member 1 |
19 |
57452905, 57452905 |
NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592 |
72133 |
18 |
pseudouridine synthesis RNA binding nucleus cytoplasm mitochondrion cytosol RNA processing tRNA modification RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity mRNA pseudouridine synthesis mRNA pseudouridine synthesis |
|
| TC0200001741.mm.2 |
Bub1b |
BUB1B, mitotic checkpoint serine/threonine kinase |
2 |
118598210 |
NM_009773, BC031577 NM_009773, BC031577 |
12236 |
96 |
nucleotide binding chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus chromosome cytoplasm spindle cytosol protein phosphorylation apoptotic process cell cycle metaphase/anaphase transition of mitotic cell cycle mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity perinuclear region of cytoplasm cell division meiotic sister chromatid cohesion, centromeric protein localization to chromosome, centromeric region |
04110 |
| TC0200004725.mm.2 |
Tasp1 |
taspase, threonine aspartase 1 |
2 |
-139833478, -139976218 |
NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 |
75812 |
25 |
threonine-type endopeptidase activity threonine-type endopeptidase activity cytoplasm proteolysis peptidase activity hydrolase activity identical protein binding positive regulation of transcription, DNA-templated protein maturation |
|
| TC1100004301.mm.2 |
Trim47 |
tripartite motif-containing 47 |
11 |
-116105749 |
NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 NM_001205081, NM_172570, BC132148, BC137953, BC145059 |
217333 |
23 |
ubiquitin-protein transferase activity ubiquitin-protein transferase activity nucleus cytoplasm cytosol zinc ion binding protein ubiquitination protein ubiquitination transferase activity metal ion binding |
|
| TC0600003003.mm.2 |
Ankrd26 |
ankyrin repeat domain 26 |
6 |
-118501299 |
NM_001081112 |
232339 |
22 |
protein binding cytoplasm centrosome actin cytoskeleton regulation of lipid metabolic process regulation of fatty acid metabolic process negative regulation of multicellular organism growth glucose homeostasis negative regulation of fat cell differentiation negative regulation of organ growth negative regulation of insulin receptor signaling pathway regulation of feeding behavior negative regulation of ERK1 and ERK2 cascade |
|
| TC0X00002689.mm.2 |
Ophn1 |
oligophrenin 1 |
X |
-98554279, -98873725 |
NM_052976, BC004845 NM_052976, BC004845 |
94190 |
39 |
actin binding GTPase activator activity GTPase activator activity protein binding phospholipid binding cytoplasm cytoplasm endocytosis signal transduction nervous system development actin cytoskeleton actin cytoskeleton cerebellar granule cell differentiation cerebral cortex neuron differentiation actin cytoskeleton organization actin cytoskeleton organization cell junction regulation of endocytosis regulation of endocytosis neuron differentiation dendrite neuron projection development cell junction assembly regulation of Rho protein signal transduction ionotropic glutamate receptor binding cell projection terminal bouton terminal bouton dendritic spine dendritic spine establishment of epithelial cell apical/basal polarity synapse synaptic vesicle endocytosis synaptic vesicle endocytosis synaptic vesicle endocytosis cell morphogenesis involved in neuron differentiation regulation of synaptic transmission, glutamatergic regulation of synaptic transmission, glutamatergic maintenance of postsynaptic specialization structure glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization negative regulation of proteasomal protein catabolic process negative regulation of proteasomal protein catabolic process |
|
| TC1800000019.mm.2 |
Svil |
supervillin |
18 |
5046588, 5046588 |
NM_153153 |
225115 |
32 |
actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm cytosol cytoskeleton plasma membrane cytoskeleton organization skeletal muscle tissue development actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton membrane cell junction cell projection costamere actin filament severing actin filament binding actin filament binding barbed-end actin filament capping |
|
| TC0100001303.mm.2 |
Aspm |
abnormal spindle microtubule assembly |
1 |
139454772 |
NM_009791 |
12316 |
49 |
spindle pole neuron migration neuron migration positive regulation of neuroblast proliferation positive regulation of neuroblast proliferation calmodulin binding nucleus cytoplasm centrosome cytoskeleton microtubule cell cycle spindle organization spermatogenesis brain development male gonad development apical plasma membrane forebrain neuroblast division cerebral cortex development midbody midbody microtubule minus-end negative regulation of neuron differentiation negative regulation of asymmetric cell division oogenesis developmental growth cell division regulation of meiotic cell cycle spindle localization maintenance of centrosome location meiotic spindle positive regulation of canonical Wnt signaling pathway spindle assembly involved in meiosis neuronal stem cell population maintenance mitotic spindle pole mitotic spindle pole |
|
| TC0200003401.mm.2 |
Strbp |
spermatid perinuclear RNA binding protein |
2 |
-37569867, -37569867, -37569867, -37569867 |
NM_009261, BC014710 NM_009261, BC014710 |
20744 |
32 |
manchette RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding nucleus cytoplasm cytoskeleton movement of cell or subcellular component multicellular organism development spermatogenesis spermatid development mechanosensory behavior microtubule binding microtubule cytoskeleton tubulin binding cell differentiation |
|
| TC1300001205.mm.2 |
Depdc1b |
DEP domain containing 1B |
13 |
108316336 |
NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331 |
218581 |
16 |
molecular_function GTPase activator activity signal transduction cell migration positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway intracellular signal transduction |
|
| TC0500000307.mm.2 |
|
|
|
|
NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 |
|
|
nucleotide binding UTP binding catalytic activity aspartate carbamoyltransferase activity aspartate carbamoyltransferase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity dihydroorotase activity dihydroorotase activity protein kinase activity ATP binding nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol 'de novo' pyrimidine nucleobase biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UTP biosynthetic process UTP biosynthetic process cellular amino acid metabolic process glutamine metabolic process glutamine metabolic process nitrogen compound metabolic process metabolic process zinc ion binding nuclear matrix amino acid binding transferase activity carboxyl- or carbamoyltransferase activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ligase activity drug metabolic process peptidyl-threonine phosphorylation citrulline biosynthetic process citrulline biosynthetic process enzyme binding response to insulin protein-containing complex response to starvation identical protein binding cell projection neuronal cell body terminal bouton protein autophosphorylation metal ion binding |
|
| TC1200000675.mm.2 |
Mthfd1 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase |
12 |
76255231 |
NM_138745, BC008523 NM_138745, BC008523 |
108156 |
53 |
histidine biosynthetic process nucleotide binding neutrophil homeostasis neural tube closure catalytic activity formate-tetrahydrofolate ligase activity formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity ATP binding cytoplasm mitochondrion cytosol cytosol purine nucleotide biosynthetic process methionine metabolic process one-carbon metabolic process heart development metabolic process cellular amino acid biosynthetic process serine family amino acid metabolic process serine family amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate biosynthetic process 10-formyltetrahydrofolate biosynthetic process oxidoreductase activity hydrolase activity ligase activity transsulfuration tetrahydrofolate interconversion tetrahydrofolate interconversion tetrahydrofolate interconversion somite development |
00670 01100 |
| TC1300001419.mm.2 |
Gtpbp4 |
GTP binding protein 4 |
13 |
-8972477 |
NM_027000, BC025431 NM_027000, BC025431 |
69237 |
30 |
regulation of cyclin-dependent protein serine/threonine kinase activity nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus nucleoplasm nucleolus cytoplasm cytosol negative regulation of DNA replication negative regulation of cell population proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination nuclear membrane negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization |
03008 |
| TC1100003345.mm.2 |
Myo1d |
myosin ID |
11 |
-80482126 |
NM_177390, BC150765 NM_177390, BC150765 |
338367 |
34 |
microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding protein binding calmodulin binding ATP binding cytoplasm endosome smooth endoplasmic reticulum plasma membrane microvillus brush border brush border actin filament organization negative regulation of phosphatase activity protein transport actin cytoskeleton membrane basolateral plasma membrane myosin complex protein domain specific binding vesicle transport along actin filament axon axolemma actin-dependent ATPase activity actin-dependent ATPase activity cytoplasmic vesicle vesicle cell projection neuron projection neuronal cell body neuronal cell body myelin sheath myelin sheath myelin sheath plasma membrane raft calcium-dependent protein binding actin filament binding actin filament binding cellular localization apical dendrite |
|
| TC1400002863.mm.2 |
Ipo4 |
importin 4 |
14 |
-55625399 |
NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150 |
75751 |
25 |
chromatin protein binding nucleus cytoplasm DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein import into nucleus protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding protein-containing complex ribosome biogenesis nuclear import signal receptor activity |
|
| TC0900000581.mm.2 |
Nxpe4 |
neurexophilin and PC-esterase domain family, member 4 |
9 |
48362040 |
NM_172921, BC085195, BC094249 NM_172921, BC085195, BC094249 NM_172921, BC085195, BC094249 |
244853 |
13 |
molecular_function extracellular region biological_process |
|
| TC0400001215.mm.2 |
Stil |
Scl/Tal1 interrupting locus |
4 |
115000117 |
NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493 |
20460 |
29 |
embryonic axis specification in utero embryonic development neural tube closure heart looping protein binding cytoplasm centrosome centrosome centriole centriole cytoskeleton mitotic spindle organization mitotic spindle organization smoothened signaling pathway smoothened signaling pathway multicellular organism development determination of left/right symmetry neural tube development forebrain development notochord development floor plate development multicellular organism growth identical protein binding negative regulation of apoptotic process positive regulation of cyclin-dependent protein serine/threonine kinase activity regulation of centriole replication centrosome duplication centrosome duplication centrosome duplication mitotic spindle checkpoint protein localization to centrosome protein localization to centrosome non-motile cilium assembly |
|
| TC0300000354.mm.2 |
Noct |
nocturnin |
3 |
51224446 |
NM_009834, BC139369, BC139370 NM_009834, BC139369, BC139370 NM_009834, BC139369, BC139370 |
12457 |
48 |
3'-5'-exoribonuclease activity deadenylation-dependent decapping of nuclear-transcribed mRNA P-body RNA binding mRNA binding poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus cytoplasm mitochondrion NADP metabolic process circadian rhythm circadian rhythm response to extracellular stimulus negative regulation of gene expression hydrolase activity NADP phosphatase activity response to lipopolysaccharide circadian regulation of gene expression P-body assembly regulation of circadian rhythm positive regulation of fat cell differentiation negative regulation of osteoblast differentiation regulation of embryonic development metal ion binding mRNA stabilization perinuclear region of cytoplasm rhythmic process NADPH phosphatase activity |
|
| TC0100001699.mm.2 |
Sccpdh |
saccharopine dehydrogenase (putative) |
1 |
179668230 |
NM_178653, BC025803 NM_178653, BC025803 |
109232 |
18 |
molecular_function mitochondrion mitochondrion lipid droplet lipid droplet plasma membrane glycolipid biosynthetic process oxidoreductase activity midbody |
|
| MG-1-pos-10341135_st |
|
|
|
|
|
|
|
|
|
| TC0800001533.mm.2 |
Rab4a |
RAB4A, member RAS oncogene family |
8 |
123805995 |
NM_009003, BC138508 NM_009003, BC138508 |
19341 |
35 |
nucleotide binding ATPase activator activity GTPase activity protein binding GTP binding cytoplasm endosome endosome cytosol plasma membrane small GTPase mediated signal transduction protein transport membrane GDP binding antigen processing and presentation syntaxin binding regulation of endocytosis regulation of endocytosis cytoplasmic vesicle membrane vesicle Rab protein signal transduction insulin-responsive compartment insulin-responsive compartment ionotropic glutamate receptor binding intracellular membrane-bounded organelle perinuclear region of cytoplasm ATPase binding recycling endosome extracellular exosome postsynaptic recycling endosome postsynaptic recycling endosome anchored component of synaptic vesicle membrane |
04144 |
| TC0400000133.mm.2 |
Tmem64 |
transmembrane protein 64 |
4 |
15265819 |
NM_181401, BC030341 NM_181401, BC030341 |
100201 |
20 |
protein binding endoplasmic reticulum membrane integral component of membrane regulation of ATPase activity positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of bone resorption regulation of cytosolic calcium ion concentration negative regulation of canonical Wnt signaling pathway |
|
| TC0400001743.mm.2 |
Akr7a5 |
aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) |
4 |
139310743 |
NM_025337, BC031857 NM_025337, BC031857 |
110198 |
25 |
alditol:NADP+ 1-oxidoreductase activity nuclear envelope cytoplasm mitochondrion Golgi apparatus cytosol oxidoreductase activity phenanthrene-9,10-epoxide hydrolase activity daunorubicin metabolic process doxorubicin metabolic process |
|
| TC1000003023.mm.2 |
Hmga2 |
high mobility group AT-hook 2 |
10 |
-120361267 |
NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085 NM_010441, BC052158, BC069985, BC085085 |
15364 |
139 |
negative regulation of transcription by RNA polymerase II nuclear chromosome chromatin DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding minor groove of adenine-thymine-rich DNA binding transcription coregulator activity protein binding nucleus nucleus nucleus regulation of transcription, DNA-templated cell cycle signal transduction spermatogenesis positive regulation of cell population proliferation male gonad development regulation of cell cycle process positive regulation of gene expression enzyme binding cell proliferation in forebrain pituitary gland development negative regulation of Wnt signaling pathway chromosome condensation adrenal gland development negative regulation of intracellular steroid hormone receptor signaling pathway somatic stem cell population maintenance somatic stem cell population maintenance regulation of growth positive regulation of multicellular organism growth positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II negative regulation of receptor signaling pathway via JAK-STAT negative regulation of astrocyte differentiation positive regulation of DNA-binding transcription factor activity cell division meiotic cell cycle regulation of growth hormone secretion lung epithelium development epithelial tube branching involved in lung morphogenesis positive regulation of epithelial cell proliferation involved in lung morphogenesis adipose tissue development fat pad development positive regulation of cell proliferation in bone marrow regulation of peptide hormone secretion positive regulation of stem cell proliferation negative regulation of cellular senescence |
|
| TC1400002341.mm.2 |
Polr3d |
polymerase (RNA) III (DNA directed) polypeptide D |
14 |
-70438747, -70438747 |
NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102 |
67065 |
19 |
immune system process DNA binding chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytosol transcription by RNA polymerase III positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC1500001347.mm.2 |
Rida |
reactive intermediate imine deaminase A homolog |
15 |
-34484021 |
NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592 NM_008287, BC092375, BC125590, BC125592 |
15473 |
17 |
RNA binding mRNA binding nucleus cytoplasm mitochondrion mitochondrion mitochondrial matrix peroxisome cytosol cytosol mRNA catabolic process hydrolase activity endoribonuclease activity, producing 3'-phosphomonoesters negative regulation of translation deaminase activity deaminase activity long-chain fatty acid binding identical protein binding ion binding transition metal ion binding negative regulation of epithelial cell proliferation mRNA destabilization organonitrogen compound catabolic process organonitrogen compound catabolic process |
|
| TC1300000045.mm.2 |
Idi1 |
isopentenyl-diphosphate delta isomerase |
13 |
8885605 |
NM_145360, BC004801, BC110313 NM_145360, BC004801, BC110313 NM_145360, BC004801, BC110313 |
319554 |
26 |
magnesium ion binding isopentenyl-diphosphate delta-isomerase activity isopentenyl-diphosphate delta-isomerase activity cytoplasm mitochondrion peroxisome isoprenoid biosynthetic process isopentenyl diphosphate biosynthetic process manganese ion binding response to stilbenoid |
00900 01100 |
| TC0100001271.mm.2 |
Kif14 |
kinesin family member 14 |
1 |
136467847 |
NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258 |
381293 |
25 |
nucleotide binding regulation of cell growth microtubule motor activity ATP binding nucleus cytoplasm cytosol cytoskeleton kinesin complex microtubule microtubule plasma membrane microtubule-based movement mitotic metaphase plate congression microtubule binding microtubule binding positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed regulation of G2/M transition of mitotic cell cycle tubulin binding ATPase activity ATPase activity protein kinase binding cerebellar granular layer structural organization cerebellar Purkinje cell layer structural organization cerebellar cortex development hippocampus development olfactory bulb development cell proliferation in forebrain cerebral cortex development regulation of cell adhesion PDZ domain binding regulation of cell migration midbody SCF-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of myelination activation of protein kinase activity positive regulation of cytokinesis regulation of Rap protein signal transduction negative regulation of integrin activation substrate adhesion-dependent cell spreading negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of neuron apoptotic process negative regulation of neuron apoptotic process establishment of protein localization spindle midzone cell division Flemming body regulation of cell maturation regulation of G1/S transition of mitotic cell cycle |
|
| TC0900000639.mm.2 |
Poglut3 |
protein O-glucosyltransferase 3 |
9 |
53384022 |
NM_212445 |
68304 |
16 |
endoplasmic reticulum endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity |
|
| TC1200001306.mm.2 |
Ncapg2 |
non-SMC condensin II complex, subunit G2 |
12 |
116405435 |
NM_133762, BC076631 NM_133762, BC076631 |
76044 |
27 |
mitotic sister chromatid segregation condensin complex condensin complex condensin complex inner cell mass cell proliferation protein binding nucleus nucleus nucleoplasm transcription by RNA polymerase II transcription by RNA polymerase II cell cycle nuclear speck erythrocyte differentiation erythrocyte differentiation chromosome condensation methylated histone binding bHLH transcription factor binding cell division transcription regulator inhibitor activity |
|
| TC0100002413.mm.2 |
Raph1 |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
1 |
-60483184 |
NM_001045513 |
77300 |
23 |
protein binding cytosol cytosol plasma membrane plasma membrane nuclear body cell leading edge axon extension |
|
| TC0100000526.mm.2 |
Fastkd2 |
FAST kinase domains 2 |
1 |
63730624 |
NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813 NM_172422, BC008271, BC057208, BC080813 |
75619 |
19 |
RNA binding protein kinase activity mitochondrion mitochondrion mitochondrial inner membrane rRNA binding ribonucleoprotein granule ribosome biogenesis mitochondrial nucleoid positive regulation of mitochondrial translation apoptotic process in response to mitochondrial fragmentation mitochondrial large ribosomal subunit assembly |
|
| TC1100000544.mm.2 |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
11 |
50377677, 50378290, 50377796, 50378235, 50376989 |
NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224 |
59013 |
52 |
nucleic acid binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm spliceosomal complex cytosol mRNA processing RNA splicing identical protein binding regulation of RNA splicing regulation of RNA splicing catalytic step 2 spliceosome cellular response to interleukin-7 ribonucleoprotein complex |
|
| TC1300001560.mm.2 |
H1f5 |
H1.5 linker histone, cluster member |
13 |
-21779831 |
NM_020034, BC146469 NM_020034, BC146469 |
56702 |
34 |
nucleosome DNA binding double-stranded DNA binding protein binding nucleus chromosome nucleosome assembly muscle organ development nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing negative regulation of DNA recombination |
|
| TC1600001124.mm.2 |
Adcy9 |
adenylate cyclase 9 |
16 |
-4284885 |
NM_009624, BC166017 NM_009624, BC166017 |
11515 |
44 |
nucleotide binding in utero embryonic development adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane integral component of plasma membrane integral component of plasma membrane cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway cyclic nucleotide biosynthetic process membrane integral component of membrane lyase activity phosphorus-oxygen lyase activity axon dendrite intracellular signal transduction metal ion binding adenylate cyclase-activating adrenergic receptor signaling pathway |
00230 04020 04062 04114 04270 04540 04912 04914 04916 04962 04970 04971 04972 04976 05414 |
| TC0X00000454.mm.2 |
Stk26 |
serine/threonine kinase 26 |
X |
50841370 |
NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 |
70415 |
20 |
Golgi membrane nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus Golgi-associated vesicle cytosol protein phosphorylation apoptotic process cellular response to starvation membrane kinase activity phosphorylation apical plasma membrane transferase activity microvillus assembly negative regulation of cell migration response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process protein autophosphorylation metal ion binding perinuclear region of cytoplasm cell periphery regulation of hydrogen peroxide-induced cell death |
|
| TC0200000354.mm.2 |
Pdss1 |
prenyl (solanesyl) diphosphate synthase, subunit 1 |
2 |
22895521, 22895521 |
NM_019501, BC026820 NM_019501, BC026820 |
56075 |
18 |
trans-hexaprenyltranstransferase activity trans-hexaprenyltranstransferase activity prenyltransferase activity protein binding mitochondrion ubiquinone biosynthetic process ubiquinone biosynthetic process ubiquinone biosynthetic process isoprenoid biosynthetic process isoprenoid biosynthetic process isoprenoid biosynthetic process transferase activity metal ion binding protein heterodimerization activity trans-octaprenyltranstransferase activity all-trans-decaprenyl-diphosphate synthase activity transferase complex transferase complex transferase complex |
00900 |
| TC1900000758.mm.2 |
Smc3 |
structural maintenance of chromosomes 3 |
19 |
53600395 |
NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935 |
13006 |
75 |
nucleotide binding chromosome, centromeric region chromatin lateral element chromatin binding protein binding ATP binding basement membrane nucleus nucleoplasm nucleoplasm chromosome regulation of DNA replication DNA repair cellular response to DNA damage stimulus cell cycle sister chromatid cohesion cohesin complex cohesin complex nuclear matrix stem cell population maintenance meiotic cohesin complex meiotic cohesin complex nuclear meiotic cohesin complex mediator complex binding protein heterodimerization activity beta-tubulin binding chromosome organization cell division meiotic cell cycle meiotic cell cycle dynein complex binding mitotic spindle assembly mitotic spindle pole |
04110 04114 |
| TC1500002037.mm.2 |
Hdac10 |
histone deacetylase 10 |
15 |
-89123302 |
NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 |
170787 |
24 |
histone deacetylase complex negative regulation of transcription by RNA polymerase II histone deacetylase activity nucleus nucleoplasm cytoplasm DNA repair DNA recombination regulation of transcription, DNA-templated autophagy cellular response to DNA damage stimulus macroautophagy histone deacetylation hydrolase activity deacetylase activity enzyme binding positive regulation of mismatch repair peptidyl-lysine deacetylation homologous recombination histone deacetylase binding negative regulation of transcription, DNA-templated metal ion binding acetylputrescine deacetylase activity acetylspermidine deacetylase activity polyamine deacetylation spermidine deacetylation |
|
| TC0200004440.mm.2 |
Oip5 |
Opa interacting protein 5 |
2 |
-119609531 |
NM_001042653, BC115883, BC116660 NM_001042653, BC115883, BC116660 NM_001042653, BC115883, BC116660 |
70645 |
14 |
chromosome, centromeric region chromatin chromatin nucleus nucleus nucleus chromosome cell cycle chromosome segregation chromocenter Cajal body nuclear speck CENP-A containing nucleosome assembly identical protein binding intracellular membrane-bounded organelle metal ion binding cell division |
|
| TC0X00003175.mm.2 |
Tsr2 |
TSR2 20S rRNA accumulation |
X |
-151087093 |
NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668 NM_001164578, NM_175146, NR_028392, BC049668 |
69499 |
16 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) molecular_function rRNA processing |
|
| TC0800002236.mm.2 |
Spcs3 |
signal peptidase complex subunit 3 homolog (S. cerevisiae) |
8 |
-54520432 |
NM_029701, BC054817 NM_029701, BC054817 |
76687 |
18 |
endoplasmic reticulum signal peptidase complex signal peptide processing proteolysis peptidase activity membrane integral component of membrane hydrolase activity viral protein processing intracellular membrane-bounded organelle protein targeting to ER |
03060 |
| TC0500000434.mm.2 |
Lyar |
Ly1 antibody reactive clone |
5 |
38220481 |
NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927 |
17089 |
30 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II photoreceptor outer segment immune system process DNA binding DNA binding nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm rRNA processing rRNA processing activating transcription factor binding identical protein binding cell projection innate immune response negative regulation of innate immune response positive regulation of transcription by RNA polymerase I metal ion binding erythrocyte development positive regulation of phagocytosis transcription regulator inhibitor activity |
|
| TC0700002057.mm.2 |
Ap2a2 |
adaptor-related protein complex 2, alpha 2 subunit |
7 |
141562179 |
NM_007459, BC058099 NM_007459, BC058099 |
11772 |
78 |
protein binding plasma membrane clathrin-coated pit intracellular protein transport endocytosis receptor-mediated endocytosis synaptic vesicle lipid binding protein transport membrane vesicle-mediated transport kinase binding protein kinase binding protein domain specific binding membrane coat AP-2 adaptor complex AP-2 adaptor complex AP-2 adaptor complex clathrin adaptor complex secretory granule cytoplasmic vesicle phosphatidylinositol binding clathrin adaptor activity protein-containing complex binding clathrin-dependent endocytosis clathrin-dependent endocytosis clathrin-dependent endocytosis disordered domain specific binding cargo adaptor activity regulation of hematopoietic stem cell differentiation |
04144 05016 |
| TC0200003697.mm.2 |
Spc25 |
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) |
2 |
-69193894 |
NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 |
66442 |
23 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cytosol cell cycle mitotic spindle organization chromosome segregation chromosome segregation Ndc80 complex Ndc80 complex cell division |
|
| TC1500000392.mm.2 |
Deptor |
DEP domain containing MTOR-interacting protein |
15 |
55112316, 55133435 |
NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690 |
97998 |
42 |
negative regulation of protein kinase activity negative regulation of TOR signaling intracellular signal transduction negative regulation of cell size regulation of extrinsic apoptotic signaling pathway |
|
| TC0600000962.mm.2 |
Smyd5 |
SET and MYND domain containing 5 |
6 |
85431975 |
NM_144918, BC016525 NM_144918, BC016525 |
232187 |
22 |
molecular_function cellular_component biological_process methyltransferase activity transferase activity methylation metal ion binding |
|
| TC0900001461.mm.2 |
Ngp |
neutrophilic granule protein |
9 |
110419807 |
NM_008694, BC119403, BC119405 NM_008694, BC119403, BC119405 NM_008694, BC119403, BC119405 |
18054 |
22 |
cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space defense response negative regulation of peptidase activity negative regulation of angiogenesis peptidase inhibitor activity cytoplasmic vesicle negative regulation of lymphangiogenesis |
|
| TC0500001251.mm.2 |
Pop5 |
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae) |
5 |
115235850 |
NM_026398, BC022670 NM_026398, BC022670 |
117109 |
19 |
ribonuclease MRP activity ribonuclease MRP complex ribonuclease MRP complex ribonuclease MRP complex tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolar ribonuclease P complex nucleolus rRNA processing rRNA processing tRNA processing tRNA processing RNA metabolic process hydrolase activity multimeric ribonuclease P complex ribonuclease P RNA binding |
03008 03013 |
| TC1100003318.mm.2 |
Wsb1 |
WD repeat and SOCS box-containing 1 |
11 |
-79239381, -79239382 |
NM_001042565, NM_019653, BC053391 NM_001042565, NM_019653, BC053391 NM_001042565, NM_019653, BC053391 |
78889 |
31 |
biological_process intracellular signal transduction |
|
| TC0600001998.mm.2 |
Tmem209 |
transmembrane protein 209 |
6 |
-30481232, -30481038 |
NM_178625, BC052187, BC057109 NM_178625, BC052187, BC057109 NM_178625, BC052187, BC057109 |
72649 |
15 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC1700001138.mm.2 |
Wdr43 |
WD repeat domain 43 |
17 |
71616214 |
NM_175639 |
72515 |
22 |
chromatin RNA polymerase II complex binding fibrillar center transcription elongation regulator activity RNA binding protein binding nucleus nucleoplasm nucleolus nucleolus rRNA processing regulation of transcription elongation from RNA polymerase II promoter ribosome biogenesis positive regulation of transcription by RNA polymerase I regulation of stem cell population maintenance positive regulation of rRNA processing |
03008 |
| TC1600001378.mm.2 |
Tra2b |
transformer 2 beta |
16 |
-22244551 |
NM_009186, BC061177, BC086795 NM_009186, BC061177, BC086795 NM_009186, BC061177, BC086795 |
20462 |
54 |
regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding protein binding nucleus nucleus nuclear inner membrane nucleoplasm spliceosomal complex spliceosomal complex mRNA processing RNA splicing protein domain specific binding cerebral cortex regionalization protein-containing complex pre-mRNA binding pre-mRNA binding identical protein binding regulation of RNA splicing negative regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome perinuclear region of cytoplasm poly-purine tract binding cellular response to glucose stimulus embryonic brain development |
03040 |
| TC0400002527.mm.2 |
Arhgef39 |
Rho guanine nucleotide exchange factor (GEF) 39 |
4 |
-43496143 |
NM_001013377, BC080700 NM_001013377, BC080700 |
230098 |
13 |
guanyl-nucleotide exchange factor activity plasma membrane plasma membrane membrane positive regulation of cell migration positive regulation of cell migration regulation of Rho protein signal transduction |
|
| TC0600001254.mm.2 |
Fancd2 |
Fanconi anemia, complementation group D2 |
6 |
113531681, 113531681 |
NM_001033244, BC139004 NM_001033244, BC139004 |
211651 |
85 |
condensed chromosome condensed chromosome protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytosol DNA repair cellular response to DNA damage stimulus cell cycle homologous chromosome pairing at meiosis homologous chromosome pairing at meiosis multicellular organism development gamete generation response to gamma radiation nuclear body intra-S DNA damage checkpoint cellular response to oxidative stress interstrand cross-link repair regulation of regulatory T cell differentiation brain morphogenesis regulation of inflammatory response regulation of DNA-binding transcription factor activity DNA polymerase binding DNA polymerase binding neuronal stem cell population maintenance double-strand break repair involved in meiotic recombination regulation of CD40 signaling pathway |
|
| TC0400004186.mm.2 |
Nfia |
nuclear factor I/A |
4 |
97581942, 97777625 |
NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878 NM_001122953, NM_010905, BC075702, BC122878 |
18027 |
121 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding chromatin binding DNA-binding transcription factor activity intracellular anatomical structure nucleus nucleus nucleus nucleoplasm DNA replication regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription factor binding cell junction positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II synapse maturation ureter development |
|
| TC1700000819.mm.2 |
Mmut |
methylmalonyl-Coenzyme A mutase |
17 |
40934684 |
NM_008650, BC019175 NM_008650, BC019175 |
17850 |
42 |
catalytic activity GTPase activity methylmalonyl-CoA mutase activity methylmalonyl-CoA mutase activity methylmalonyl-CoA mutase activity cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial matrix post-embryonic development isomerase activity intramolecular transferase activity cobalamin binding identical protein binding protein homodimerization activity positive regulation of GTPase activity metal ion binding homocysteine metabolic process modified amino acid binding |
00280 00630 00640 01100 |
| TC0X00001371.mm.2 |
Rnf128 |
ring finger protein 128 |
X |
139610619, 139563339 |
NM_001254761, NM_023270, BC010477 NM_001254761, NM_023270, BC010477 NM_001254761, NM_023270, BC010477 |
66889 |
49 |
negative regulation of cytokine production cytoplasm late endosome late endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus cytoskeleton ubiquitin-dependent protein catabolic process membrane integral component of membrane transferase activity regulation of protein stability metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| TC1000001282.mm.2 |
E2f7 |
E2F transcription factor 7 |
10 |
110745438 |
NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F NM_178609, BC145429, BC150772, E2F |
52679 |
39 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific placenta development sprouting angiogenesis sprouting angiogenesis DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus cell cycle negative regulation of cell population proliferation negative regulation of cell population proliferation nuclear speck DNA damage response, signal transduction by p53 class mediator negative regulation of cytokinesis positive regulation of DNA endoreduplication identical protein binding positive regulation of transcription by RNA polymerase II trophoblast giant cell differentiation chorionic trophoblast cell differentiation hepatocyte differentiation negative regulation of transcription involved in G1/S transition of mitotic cell cycle RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding negative regulation of G1/S transition of mitotic cell cycle |
|
| TC0400000530.mm.2 |
Stx17 |
syntaxin 17 |
4 |
48124918 |
NM_026343, BC028639 NM_026343, BC028639 |
67727 |
23 |
SNARE binding SNARE binding autophagosome membrane autophagosome membrane SNAP receptor activity SNAP receptor activity cytoplasm autophagosome autophagosome endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment cytosol plasma membrane intracellular protein transport exocytosis endoplasmic reticulum to Golgi vesicle-mediated transport vesicle fusion autophagy Golgi organization endomembrane system membrane integral component of membrane vesicle-mediated transport autophagosome membrane docking protein kinase binding protein phosphatase binding COPII-coated ER to Golgi transport vesicle smooth endoplasmic reticulum membrane HOPS complex SNARE complex SNARE complex cytoplasmic vesicle protein localization to phagophore assembly site mitochondria-associated endoplasmic reticulum membrane vesicle docking endoplasmic reticulum-Golgi intermediate compartment organization autophagosome maturation |
04130 |
| TC0600003000.mm.2 |
Bms1 |
BMS1, ribosome biogenesis factor |
6 |
-118383380 |
NM_194339, BC057054 NM_194339, BC057054 |
213895 |
17 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleoplasm chromosome nucleolus 90S preribosome U3 snoRNA binding |
03008 |
| TC0200005489.mm.2 |
Zfp965 |
zinc finger protein 965 |
2 |
175470024 |
NM_001242944 |
100503949 |
1 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific nucleoplasm regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC0800001245.mm.2 |
Slc7a6 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 |
8 |
106168853, 106168920 |
NM_178798, BC038404 NM_178798, BC038404 |
330836 |
20 |
amino acid transmembrane transport plasma membrane amino acid transport basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity antiporter activity ornithine transport membrane integral component of membrane transmembrane transporter activity intracellular membrane-bounded organelle transmembrane transport basic amino acid transmembrane transport |
|
| TC1500001698.mm.2 |
Slc45a4 |
solute carrier family 45, member 4 |
15 |
-73577423, -73577423, -73577423 |
NM_001033219, NM_001168255, BC056501 NM_001033219, NM_001168255, BC056501 NM_001033219, NM_001168255, BC056501 |
106068 |
24 |
sucrose:proton symporter activity sucrose:proton symporter activity sucrose transport membrane integral component of membrane |
|
| MG-1-pos-10340825_st |
|
|
|
|
|
|
|
|
|
| TC0700001131.mm.2 |
Ticrr |
TOPBP1-interacting checkpoint and replication regulator |
7 |
79660195 |
NM_029835, BC158103 NM_029835, BC158103 |
77011 |
18 |
chromatin binding chromatin binding nucleus nucleus nucleoplasm cytosol DNA replication DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint response to ionizing radiation regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation mitotic DNA replication checkpoint intracellular membrane-bounded organelle |
|
| TC0800001639.mm.2 |
Shcbp1 |
Shc SH2-domain binding protein 1 |
8 |
-4735975 |
NM_011369, BC070455 NM_011369, BC070455 |
20419 |
24 |
protein binding cellular_component cytoplasm cytoskeleton fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway SH2 domain binding regulation of neural precursor cell proliferation |
|
| MG-1-pos-10342215_st |
|
|
|
|
|
|
|
|
|
| TC1100001899.mm.2 |
Nup85 |
nucleoporin 85 |
11 |
115564443 |
NM_001002929, BC079856 NM_001002929, BC079856 |
445007 |
21 |
chromosome, centromeric region kinetochore nucleus nuclear pore nucleoplasm chromosome cytoplasm cytosol cytoskeleton plasma membrane mRNA export from nucleus protein import into nucleus chemotaxis protein transport membrane structural constituent of nuclear pore cytokine-mediated signaling pathway lamellipodium assembly nuclear pore outer ring nuclear pore outer ring CCR2 chemokine receptor binding positive regulation of transcription, DNA-templated macrophage chemotaxis mRNA transport nephron development |
03013 |
| TC0900001441.mm.2 |
Nme6 |
NME/NM23 nucleoside diphosphate kinase 6 |
9 |
109832793 |
NM_018757, BC002007, NME/NM23 NM_018757, BC002007, NME/NM23 NM_018757, BC002007, NME/NM23 |
54369 |
23 |
nucleotide binding nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding mitochondrion mitochondrion mitochondrion nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process kinase activity phosphorylation transferase activity negative regulation of cell growth negative regulation of cell growth negative regulation of mitotic nuclear division negative regulation of mitotic nuclear division metal ion binding |
00230 00240 01100 |
| TC1600002056.mm.2 |
Urb1 |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
16 |
-90751526 |
NM_029497 |
207932 |
16 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleus nucleolus nucleolus |
|
| TC1400000858.mm.2 |
Sacs |
sacsin |
14 |
61138456, 61138456 |
NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 |
50720 |
26 |
cytoplasm Hsp70 protein binding low-density lipoprotein particle receptor binding chaperone binding |
|
| TC0700002744.mm.2 |
Zfp146 |
zinc finger protein 146 |
7 |
-30160486 |
NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039 |
26465 |
22 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleic acid binding DNA binding nucleus nucleolus cytosol regulation of transcription by RNA polymerase II metal ion binding |
|
| TC0200004589.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0200000352.mm.2 |
Apbb1ip |
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
2 |
22774326 |
NM_019456, BC023110 NM_019456, BC023110 |
54519 |
28 |
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell protein binding cytoplasm cytosol cytosol cytosol cytoskeleton plasma membrane plasma membrane plasma membrane signal transduction membrane cell junction T cell receptor complex cell projection positive regulation of cell adhesion |
|
| TC0900002613.mm.2 |
Tcf12 |
transcription factor 12 |
9 |
-71844251, -71844251, -71844251 |
NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 NM_001253862, NM_001253863, NM_001253864, NM_001253865, NM_011544, BC037097 |
21406 |
124 |
chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of transcription by RNA polymerase II multicellular organism development nervous system development transcription factor binding positive regulation of gene expression nuclear speck cell differentiation cAMP response element binding intracellular membrane-bounded organelle bHLH transcription factor binding positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II SMAD binding protein heterodimerization activity protein dimerization activity E-box binding HMG box domain binding RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding |
|
| TC0800001204.mm.2 |
Cbfb |
core binding factor beta |
8 |
105170673 |
NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 NM_001161456, NM_001161457, NM_001161458, NM_022309, BC006763, BC026749, BC040752 |
12400 |
145 |
negative regulation of transcription by RNA polymerase II protein polyubiquitination ossification osteoblast differentiation DNA binding transcription coactivator activity protein binding nucleus nucleoplasm regulation of transcription by RNA polymerase II core-binding factor complex core-binding factor complex lymphocyte differentiation myeloid cell differentiation protein-containing complex negative regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding sequence-specific DNA binding positive regulation of transcription by RNA polymerase II cell maturation definitive hemopoiesis |
|
| TC1000001868.mm.2 |
Eya4 |
EYA transcriptional coactivator and phosphatase 4 |
10 |
-23102961, -23102961 |
NM_010167, BC120898, BC120899 NM_010167, BC120898, BC120899 NM_010167, BC120898, BC120899 |
14051 |
28 |
phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus cytoplasm DNA repair chromatin organization cellular response to DNA damage stimulus multicellular organism development sensory perception of sound transcription factor binding histone dephosphorylation hydrolase activity cell differentiation middle ear morphogenesis positive regulation of DNA repair metal ion binding anatomical structure development negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
|
| MG-1-neg-10339405_st |
|
|
|
|
|
|
|
|
|
| MG-1-pos-10343496_st |
|
|
|
|
|
|
|
|
|
| TC0800002618.mm.2 |
Neto2 |
neuropilin (NRP) and tolloid (TLL)-like 2 |
8 |
-85636717, -85636717 |
NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 NM_001081324, BC151050, BC157941, BC172104, BC172139 |
74513 |
35 |
plasma membrane postsynaptic density membrane integral component of membrane ionotropic glutamate receptor binding synapse regulation of kainate selective glutamate receptor activity |
|
| MG-1-neg-10338964_st |
|
|
|
|
|
|
|
|
|
| TC1100000407.mm.2 |
Nudcd2 |
NudC domain containing 2 |
11 |
40733660 |
NM_026023, BC005646 NM_026023, BC005646 |
52653 |
19 |
chromosome, centromeric region kinetochore chromosome cytoplasm cytosol cytoskeleton protein folding microtubule cytoskeleton intercellular bridge unfolded protein binding mitotic spindle |
|
| MG-1-neg-10344006_st |
|
|
|
|
|
|
|
|
|
| TC0100003887.mm.2 |
Nos1ap |
nitric oxide synthase 1 (neuronal) adaptor protein |
1 |
-170315466, -170315466 |
NM_001109985, NM_027528, BC160272 NM_001109985, NM_027528, BC160272 NM_001109985, NM_027528, BC160272 |
70729 |
28 |
protease binding nucleus cytoplasm mitochondrion cytosol caveola biological_process Z disc PDZ domain binding T-tubule nuclear membrane sarcoplasmic reticulum membrane nitric-oxide synthase binding nitric-oxide synthase binding nitric-oxide synthase binding presynapse postsynapse glutamatergic synapse negative regulation of neuron death regulation of high voltage-gated calcium channel activity inward rectifier potassium channel complex L-type voltage-gated calcium channel complex positive regulation of peptidyl-cysteine S-nitrosylation |
|
| TC0100001595.mm.2 |
Cd244a |
CD244 molecule A |
1 |
171559192 |
NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 NM_018729, BC145067, BC150692, BC160247, CD244 |
18106 |
80 |
myeloid dendritic cell activation adaptive immune response natural killer cell activation involved in immune response natural killer cell activation involved in immune response immune system process protein binding plasma membrane immune response external side of plasma membrane external side of plasma membrane membrane integral component of membrane positive regulation of interferon-gamma production positive regulation of interleukin-8 production positive regulation of natural killer cell proliferation signaling receptor activity MHC class I protein binding innate immune response positive regulation of inositol phosphate biosynthetic process positive regulation of granzyme B production positive regulation of CD8-positive, alpha-beta T cell proliferation |
04650 |
| TC0200000274.mm.2 |
Plxdc2 |
plexin domain containing 2 |
2 |
16356303 |
NM_026162, BC057881 NM_026162, BC057881 |
67448 |
29 |
plasma membrane membrane integral component of membrane collagen-containing extracellular matrix |
|
| TC1100004268.mm.2 |
Fbxw10 |
F-box and WD-40 domain protein 10 |
11 |
62847122 |
NM_001033669, BC141212, BC172760 NM_001033669, BC141212, BC172760 NM_001033669, BC141212, BC172760 |
213980 |
13 |
cellular_component biological_process |
|
| TC0200002844.mm.2 |
Rpp38 |
ribonuclease P/MRP 38 subunit |
2 |
-3328948 |
NM_001013376, BC051448 NM_001013376, BC051448 |
227522 |
15 |
fibrillar center fibrillar center tRNA 5'-leader removal tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity nucleus nucleolus rRNA processing tRNA processing hydrolase activity multimeric ribonuclease P complex multimeric ribonuclease P complex ribonuclease P RNA binding ribonuclease P RNA binding |
03008 03013 |
| TC1100000164.mm.2 |
Fbxo48 |
F-box protein 48 |
11 |
16951409, 16951374 |
NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591 |
319701 |
10 |
molecular_function SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
| TC1100002486.mm.2 |
Npm1 |
nucleophosmin 1 |
11 |
-33152497, -33154924 |
NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 |
18148 |
155 |
ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus ribosomal small subunit export from nucleus cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) core promoter sequence-specific DNA binding regulation of cell growth granular component p53 binding nucleic acid binding DNA binding chromatin binding transcription coactivator activity RNA binding RNA binding RNA binding protein kinase inhibitor activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleus nucleoplasm nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm centrosome centrosome centrosome cytosol cytoskeleton DNA repair nucleosome assembly chromatin remodeling rRNA export from nucleus rRNA export from nucleus rRNA export from nucleus cell volume homeostasis cell volume homeostasis nucleocytoplasmic transport nucleocytoplasmic transport centrosome cycle cell aging protein localization protein localization transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation rRNA transcription posttranscriptional regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication regulation of centrosome duplication positive regulation of centrosome duplication negative regulation of centrosome duplication large ribosomal subunit small ribosomal subunit nuclear matrix nuclear speck rRNA binding enzyme binding protein kinase binding Tat protein binding positive regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process positive regulation of protein ubiquitination spindle pole centrosome regulation of protein stability protein destabilization regulation of endodeoxyribonuclease activity protein-containing complex protein-DNA complex activating transcription factor binding cellular response to UV ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis histone binding histone binding identical protein binding identical protein binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of catalytic activity protein kinase B binding regulation of DNA damage response, signal transduction by p53 class mediator regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of protein kinase activity by regulation of protein phosphorylation positive regulation of translation positive regulation of DNA replication positive regulation of protein kinase activity positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of centriole replication protein N-terminus binding negative regulation of mRNA splicing, via spliceosome negative regulation of epithelial cell proliferation protein stabilization protein stabilization positive regulation of DNA metabolic process NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity regulation of cell cycle regulation of endoribonuclease activity regulation of eIF2 alpha phosphorylation by dsRNA positive regulation of DNA-directed DNA polymerase activity regulation of mRNA stability involved in cellular response to UV positive regulation of cell cycle G2/M phase transition positive regulation of protein localization to nucleolus ribonucleoprotein complex ribonucleoprotein complex |
|
| TC0400000484.mm.2 |
Polr1e |
polymerase (RNA) I polypeptide E |
4 |
45018608 |
NM_001285800, NM_022811, BC034783 NM_001285800, NM_022811, BC034783 NM_001285800, NM_022811, BC034783 |
64424 |
30 |
RNA polymerase I general transcription initiation factor binding RNA polymerase I preinitiation complex assembly RNA polymerase I preinitiation complex assembly fibrillar center DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm nucleoplasm nucleolus RNA polymerase I complex RNA polymerase I complex transcription, DNA-templated transcription elongation from RNA polymerase I promoter nucleolar large rRNA transcription by RNA polymerase I nucleolar large rRNA transcription by RNA polymerase I |
00230 00240 01100 03020 |
| TC0300001587.mm.2 |
Depdc1a |
DEP domain containing 1a |
3 |
159495432 |
NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 |
76131 |
12 |
GTPase activator activity nucleus nucleus signal transduction transcription repressor complex transcription repressor complex intracellular signal transduction negative regulation of transcription, DNA-templated |
|
| TC0200002720.mm.2 |
|
|
|
|
NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0200002738.mm.2 |
|
|
|
|
NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0200005341.mm.2 |
|
|
|
|
NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC1500001202.mm.2 |
Brix1 |
BRX1, biogenesis of ribosomes |
15 |
-10474778 |
NM_026396, BC014832 NM_026396, BC014832 |
67832 |
23 |
ribosomal large subunit assembly RNA binding nucleus chromosome nucleolus nucleolus ribosome biogenesis |
|
| TC0200000473.mm.2 |
Wdr5 |
WD repeat domain 5 |
2 |
27515146 |
NM_080848, BC016103, BC025801 NM_080848, BC016103, BC025801 NM_080848, BC016103, BC025801 |
140858 |
64 |
histone acetyltransferase complex skeletal system development protein binding intracellular anatomical structure nucleus nucleus nucleoplasm nucleoplasm Ada2/Gcn5/Ada3 transcription activator complex Ada2/Gcn5/Ada3 transcription activator complex chromatin organization neuron projection development methylated histone binding histone methyltransferase complex histone binding histone methyltransferase activity (H3-K4 specific) histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K16 acetylation MLL3/4 complex positive regulation of gluconeogenesis Set1C/COMPASS complex Set1C/COMPASS complex histone H3-K4 methylation histone H3-K4 methylation histone H3-K4 methylation positive regulation of histone H3-K4 methylation negative regulation of histone H3-K4 methylation MLL1 complex |
|
| TC1700001439.mm.2 |
Pacrg |
PARK2 co-regulated |
17 |
-10403011 |
NM_027032, BC120740 NM_027032, BC120740 |
69310 |
35 |
G protein-coupled receptor binding manchette actin binding protein binding mitochondrion cytosol cytosol cytosol cilium spermatid development Hsp70 protein binding Hsp70 protein binding heat shock protein binding ubiquitin protein ligase binding ubiquitin protein ligase binding vesicle vesicle vesicle cellular protein localization cellular response to unfolded protein neuron projection neuron projection neuron projection alpha-tubulin binding cell body beta-tubulin binding chaperone binding chaperone binding Hsp90 protein binding Hsp90 protein binding negative regulation of cell death negative regulation of cell death negative regulation of cell death sperm midpiece |
|
| TC0X00000958.mm.2 |
Kif4 |
kinesin family member 4 |
X |
100626064 |
NM_008446, BC050946 NM_008446, BC050946 |
16571 |
43 |
nucleotide binding mitotic cytokinesis DNA binding microtubule motor activity ATP binding nucleus nucleoplasm chromosome cytoplasm cytosol cytoskeleton microtubule microtubule-based movement mitotic spindle organization microtubule binding midbody metal ion binding mitotic spindle midzone assembly iron-sulfur cluster binding |
|
| TC0100001240.mm.2 |
Ube2t |
ubiquitin-conjugating enzyme E2T |
1 |
134962564 |
NM_001278115, NM_026024, BC029213 NM_001278115, NM_026024, BC029213 NM_001278115, NM_026024, BC029213 |
67196 |
19 |
nucleotide binding protein polyubiquitination chromatin binding ubiquitin-protein transferase activity ATP binding nucleus nucleoplasm nucleolus DNA repair protein monoubiquitination cellular response to DNA damage stimulus cellular response to DNA damage stimulus transferase activity ubiquitin protein ligase binding protein K29-linked ubiquitination protein K27-linked ubiquitination protein autoubiquitination ubiquitin conjugating enzyme activity ubiquitin conjugating enzyme activity protein K63-linked ubiquitination protein K48-linked ubiquitination protein K11-linked ubiquitination protein K6-linked ubiquitination |
|
| TC0900000819.mm.2 |
Tipin |
timeless interacting protein |
9 |
64281584 |
NM_025372, BC016211 NM_025372, BC016211 |
66131 |
25 |
DNA replication checkpoint DNA replication checkpoint DNA damage checkpoint chromatin DNA binding protein binding nucleus nucleus cytoplasm cellular response to DNA damage stimulus cell cycle positive regulation of cell population proliferation response to UV replication fork protection complex intra-S DNA damage checkpoint replication fork arrest cell cycle phase transition replication fork protection cell division |
|
| TC0X00000429.mm.2 |
Utp14a |
UTP14A small subunit processome component |
X |
48256933 |
NM_028276, BC082590 NM_028276, BC082590 |
72554 |
22 |
nucleus nucleolus nucleolus cytosol rRNA processing small-subunit processome ribosome biogenesis |
03008 |
| TC1900001089.mm.2 |
Incenp |
inner centromere protein |
19 |
-9872294 |
NM_016692, BC052414 NM_016692, BC052414 |
16319 |
37 |
mitotic sister chromatid segregation mitotic cytokinesis mitotic cytokinesis chromosome, centromeric region chromosome, centromeric region kinetochore kinetochore condensed chromosome synaptonemal complex lateral element central element nucleus nucleoplasm chromosome pericentric heterochromatin cytoplasm spindle cytosol cytoskeleton microtubule cell cycle chromosome segregation meiotic chromosome condensation chromocenter histone phosphorylation nuclear body midbody midbody midbody chromosome passenger complex protein-containing complex protein serine/threonine kinase activator activity meiotic spindle midzone assembly cell division metaphase plate congression positive regulation of protein serine/threonine kinase activity regulation of mitotic cytokinesis meiotic spindle midzone |
|
| TC0400000309.mm.2 |
Rars2 |
arginyl-tRNA synthetase 2, mitochondrial |
4 |
34614956 |
NM_181406, BC024878 NM_181406, BC024878 |
109093 |
23 |
nucleotide binding aminoacyl-tRNA ligase activity arginine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrion translation tRNA aminoacylation for protein translation arginyl-tRNA aminoacylation ligase activity mitochondrial translation |
00970 |
| TC1600000376.mm.2 |
Il1rap |
interleukin 1 receptor accessory protein |
16 |
26581704, 26581704, 26581704, 26581704 |
NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 NM_001159317, NM_001159318, NM_008364, NM_134103, BC021159 |
16180 |
51 |
interleukin-33 receptor activity immune system process interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1 receptor binding interleukin-1 receptor binding protein binding extracellular region cytoplasm plasma membrane inflammatory response signal transduction membrane integral component of membrane hydrolase activity cytokine-mediated signaling pathway interleukin-2 production interleukin-4 production positive regulation of interleukin-13 production positive regulation of interleukin-5 production positive regulation of interleukin-6 production protein-containing complex interleukin-33-mediated signaling pathway innate immune response NAD(P)+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of synapse assembly NAD+ nucleotidase, cyclic ADP-ribose generating glutamatergic synapse glutamatergic synapse regulation of postsynaptic density assembly regulation of postsynaptic density assembly trans-synaptic signaling by trans-synaptic complex trans-synaptic signaling by trans-synaptic complex synaptic membrane adhesion synaptic membrane adhesion positive regulation of dendrite development regulation of presynapse assembly regulation of presynapse assembly protein tyrosine kinase binding |
04060 04210 |
| TC0400001736.mm.2 |
Pla2g2e |
phospholipase A2, group IIE |
4 |
138877941 |
NM_012044, BC027524 NM_012044, BC027524 |
26970 |
28 |
phospholipase A2 activity calcium ion binding calcium ion binding phospholipid binding extracellular region cytoplasm lipid metabolic process phospholipid metabolic process inflammatory response lipid catabolic process hydrolase activity low-density lipoprotein particle remodeling phosphatidylcholine metabolic process phosphatidylglycerol metabolic process metal ion binding calcium-dependent phospholipase A2 activity calcium-dependent phospholipase A2 activity calcium-dependent phospholipase A2 activity arachidonic acid secretion |
00564 00565 00590 00591 00592 01100 04010 04270 04370 04664 04730 04912 04972 04975 05145 |
| TC1800001156.mm.2 |
Cdc25c |
cell division cycle 25C |
18 |
-34732994 |
NM_009860, BC004669 NM_009860, BC004669 |
12532 |
51 |
G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding intracellular anatomical structure nucleus nucleus nucleus cytoplasm cytoplasm mitochondrial intermembrane space protein dephosphorylation cell cycle positive regulation of G2/M transition of mitotic cell cycle nuclear speck hydrolase activity protein kinase binding perinuclear region of cytoplasm WW domain binding cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition |
04110 04114 04914 |
| TC0800003008.mm.2 |
Gcsh |
glycine cleavage system protein H (aminomethyl carrier) |
8 |
-116981966 |
NM_026572, BC014745 NM_026572, BC014745 |
68133 |
19 |
aminomethyltransferase activity cytoplasm mitochondrion mitochondrion mitochondrion glycine cleavage complex protein lipoylation protein lipoylation glycine decarboxylation via glycine cleavage system glycine decarboxylation via glycine cleavage system enzyme binding |
|
| TC1400000177.mm.2 |
Vcl |
vinculin |
14 |
20929397 |
NM_009502, BC008520 NM_009502, BC008520 |
22330 |
214 |
stress fiber morphogenesis of an epithelium podosome dystroglycan binding actin binding structural molecule activity protein binding cytoplasm cytoskeleton actin filament plasma membrane cell-cell junction cell-cell junction adherens junction adherens junction fascia adherens focal adhesion focal adhesion cell adhesion intercalated disc actin cytoskeleton membrane Z disc lamellipodium assembly cell junction regulation of cell migration small GTPase binding ubiquitin protein ligase binding protein-containing complex adherens junction assembly protein localization to cell surface sarcolemma sarcolemma costamere costamere apical junction assembly cell-cell contact zone membrane raft alpha-catenin binding axon extension actin filament binding regulation of focal adhesion assembly epithelial cell-cell adhesion regulation of establishment of endothelial barrier regulation of protein localization to adherens junction |
04510 04520 04670 04810 05100 05146 |
| MG-1-pos-10343924_st |
|
|
|
|
|
|
|
|
|
| TC0500000048.mm.2 |
Slc25a40 |
solute carrier family 25, member 40 |
5 |
8422837 |
NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103 NM_001289595, NM_001289596, NM_178766, BC083103 |
319653 |
15 |
mitochondrion mitochondrial inner membrane membrane integral component of membrane transmembrane transporter activity transmembrane transport |
|
| TC0200001756.mm.2 |
Rpusd2 |
RNA pseudouridylate synthase domain containing 2 |
2 |
119034789 |
NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828 |
271842 |
13 |
enzyme-directed rRNA pseudouridine synthesis pseudouridine synthesis RNA binding RNA modification pseudouridine synthase activity |
|
| TC0500003096.mm.2 |
Gatc |
glutamyl-tRNA(Gln) amidotransferase, subunit C |
5 |
-115333241 |
NM_029645, BC021775 NM_029645, BC021775 |
384281 |
14 |
nucleotide binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion translation regulation of translational fidelity ligase activity glutamyl-tRNA(Gln) amidotransferase complex glutamyl-tRNA(Gln) amidotransferase complex mitochondrial translation mitochondrial translation glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNAGln biosynthesis via transamidation glutaminyl-tRNAGln biosynthesis via transamidation |
|
| TC0400003437.mm.2 |
Ctps |
cytidine 5'-triphosphate synthase |
4 |
-120539867, -120539867 |
NM_016748, BC006698 NM_016748, BC006698 |
51797 |
30 |
nucleotide binding immune system process CTP synthase activity CTP synthase activity ATP binding cytoplasm pyrimidine nucleotide biosynthetic process CTP biosynthetic process CTP biosynthetic process glutamine metabolic process ligase activity pyrimidine nucleobase biosynthetic process T cell proliferation B cell proliferation identical protein binding identical protein binding cytoophidium cytoophidium |
00240 01100 |
| TC1100001329.mm.2 |
Ska2 |
spindle and kinetochore associated complex subunit 2 |
11 |
87109260 |
NM_025377, BC117001, BC119167 NM_025377, BC117001, BC119167 NM_025377, BC117001, BC119167 |
66140 |
23 |
mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore chromosome cytoplasm cytoskeleton microtubule spindle microtubule spindle microtubule cell cycle chromosome segregation chromosome segregation microtubule binding microtubule binding regulation of microtubule polymerization or depolymerization cell division |
|
| TC0200003202.mm.2 |
Surf6 |
surfeit gene 6 |
2 |
-26890417 |
NM_009298, BC037634 NM_009298, BC037634 |
20935 |
30 |
granular component DNA binding DNA binding RNA binding RNA binding nucleus nucleoplasm nucleoplasm chromosome nucleolus nucleolus nucleolus ribosome biogenesis ribosome assembly ribosomal large subunit biogenesis ribosomal small subunit biogenesis |
|
| TC1500001534.mm.2 |
Dscc1 |
DNA replication and sister chromatid cohesion 1 |
15 |
-55076100 |
NM_183089, BC116833, BC116835 NM_183089, BC116833, BC116835 NM_183089, BC116833, BC116835 |
72107 |
16 |
chromosome, centromeric region chromosome, centromeric region chromatin chromatin DNA binding DNA clamp loader activity DNA clamp loader activity nucleus nucleoplasm DNA replication regulation of DNA replication regulation of DNA replication cell cycle mitotic sister chromatid cohesion single-stranded DNA helicase activity Ctf18 RFC-like complex Ctf18 RFC-like complex maintenance of mitotic sister chromatid cohesion maintenance of mitotic sister chromatid cohesion post-translational protein acetylation positive regulation of DNA-directed DNA polymerase activity |
|
| TC0600003342.mm.2 |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
6 |
-137477244, -137477244, -137477244 |
NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 |
13860 |
73 |
actin binding actin binding protein binding cytoplasm plasma membrane brush border cell cortex Rho protein signal transduction adult locomotory behavior regulation of cell shape exit from mitosis postsynaptic density postsynaptic density membrane Rac protein signal transduction NMDA selective glutamate receptor complex cell junction regulation of actin filament length small GTPase binding actin cytoskeleton reorganization stereocilium stereocilium bundle stereocilium tip ruffle membrane ruffle membrane regulation of Rho protein signal transduction signaling adaptor activity dendritic cell migration cell projection neuron projection synapse behavioral response to ethanol barbed-end actin filament capping barbed-end actin filament capping actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly actin crosslink formation actin crosslink formation actin polymerization-dependent cell motility glutamatergic synapse glutamatergic synapse glutamatergic synapse regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels positive regulation of ruffle assembly cellular response to leukemia inhibitory factor |
|
| TC1100003569.mm.2 |
Eme1 |
essential meiotic structure-specific endonuclease 1 |
11 |
-94644972, -94644995 |
NM_177752, BC089459 NM_177752, BC089459 |
268465 |
26 |
resolution of meiotic recombination intermediates chromatin heterochromatin DNA binding nuclease activity endonuclease activity protein binding nucleus DNA repair double-strand break repair DNA recombination cellular response to DNA damage stimulus hydrolase activity replication fork processing intra-S DNA damage checkpoint metal ion binding Holliday junction resolvase complex response to intra-S DNA damage checkpoint signaling |
03440 |
| TC1700002561.mm.2 |
Cebpz |
CCAAT/enhancer binding protein zeta |
17 |
-78919002 |
NM_001024806, BC160197 NM_001024806, BC160197 |
12607 |
24 |
transcription coactivator activity nucleus nucleus ribosome biogenesis positive regulation of transcription by RNA polymerase II |
|
| TC1900001428.mm.2 |
Pank1 |
pantothenate kinase 1 |
19 |
-34806935, -34806935 |
NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496 |
75735 |
33 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus nucleus nucleus cytosol cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity clathrin coat protein homodimerization activity recycling endosome cell periphery acetyl-CoA binding |
00770 01100 |
| TC0100001178.mm.2 |
Nucks1 |
nuclear casein kinase and cyclin-dependent kinase substrate 1 |
1 |
131910457 |
NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951 |
98415 |
32 |
double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromatin chromatin cellular glucose homeostasis chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding transcription coactivator activity nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cytoplasm cytoplasm regulation of DNA replication DNA repair chromatin organization regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus transcription factor binding release from viral latency replication fork processing interstrand cross-link repair interstrand cross-link repair glucose homeostasis positive regulation by host of viral transcription positive regulation by host of viral genome replication positive regulation of transcription by RNA polymerase II regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway regulation of DNA strand elongation cellular response to X-ray modulation by host of RNA binding by virus modulation by host of viral RNA-binding transcription factor activity |
|
| TC1800000535.mm.2 |
Snx24 |
sorting nexing 24 |
18 |
53245624 |
NM_029394, BC051168 NM_029394, BC051168 |
69226 |
15 |
cellular_component biological_process lipid binding phosphatidylinositol-5-phosphate binding protein transport membrane cytoplasmic vesicle phosphatidylinositol-3-phosphate binding phosphatidylinositol binding phosphatidylinositol-4-phosphate binding phosphatidylinositol phosphate binding |
|
| TC1600000952.mm.2 |
N6amt1 |
N-6 adenine-specific DNA methyltransferase 1 (putative) |
16 |
87354184 |
NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 NM_001159331, NM_026366, BC098330, BC116393, BC116394 |
67768 |
20 |
nucleic acid binding protein binding nucleus chromatin organization methyltransferase activity protein methyltransferase activity protein methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity toxin metabolic process transferase activity histone-lysine N-methyltransferase activity peptidyl-glutamine methylation peptidyl-glutamine methylation arsonoacetate metabolic process positive regulation of cell growth methylarsonite methyltransferase activity methylation protein-containing complex histone lysine methylation eRF1 methyltransferase complex protein-glutamine N-methyltransferase activity protein-glutamine N-methyltransferase activity S-adenosyl-L-methionine binding |
|
| TC0200000312.mm.2 |
Msrb2 |
methionine sulfoxide reductase B2 |
2 |
19371635 |
NM_029619, BC021619 NM_029619, BC021619 |
76467 |
30 |
actin binding cytoplasm mitochondrion mitochondrion response to oxidative stress zinc ion binding oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor actin filament polymerization protein repair peptide-methionine (R)-S-oxide reductase activity peptide-methionine (R)-S-oxide reductase activity L-methionine-(R)-S-oxide reductase activity metal ion binding |
|
| TC0300000880.mm.2 |
Selenbp1 |
selenium binding protein 1 |
3 |
94933082 |
NM_009150, BC011202 NM_009150, BC011202 |
20341 |
31 |
fibrillar center nucleus nucleolus cytoplasm selenium binding protein transport membrane oxidoreductase activity methanethiol oxidase activity brown fat cell differentiation |
|
| TC1100003300.mm.2 |
Tmem97 |
transmembrane protein 97 |
11 |
-78541816 |
NM_133706, BC018156, BC093511 NM_133706, BC018156, BC093511 NM_133706, BC018156, BC093511 |
69071 |
23 |
molecular_function nucleus lysosome endoplasmic reticulum endoplasmic reticulum rough endoplasmic reticulum plasma membrane membrane integral component of membrane nuclear membrane cholesterol homeostasis |
|
| TC1800000908.mm.2 |
|
|
|
|
NM_175542, NR_105777 NM_175542, NR_105777 |
|
|
molecular_function cytoplasm centrosome centriole cytoskeleton cilium centriole replication multicellular organism development determination of left/right symmetry centriole-centriole cohesion integral component of membrane ciliary basal body organization ciliary basal body ciliary basal body cell projection cilium organization |
|
| TC0700003599.mm.2 |
Wdr73 |
WD repeat domain 73 |
7 |
-80890722 |
NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940 NM_028026, NR_027976, BC028870, BC087940 |
71968 |
20 |
spindle pole spindle pole molecular_function cytoplasm cytosol cytosol cytoskeleton nucleus organization cytoplasmic microtubule organization cytoplasmic microtubule organization cleavage furrow negative regulation of apoptotic process |
|
| TC0400000091.mm.2 |
|
|
|
|
NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604 NM_001039556, NM_001256142, NM_001256145, BC057604 |
|
|
double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination nucleus nucleus nucleoplasm cellular response to DNA damage stimulus cellular response to DNA damage stimulus reciprocal meiotic recombination biological_process determination of adult lifespan response to ionizing radiation response to ionizing radiation DNA translocase activity DNA translocase activity response to drug identical protein binding |
|
| TC0800000646.mm.2 |
Mfap3l |
microfibrillar-associated protein 3-like |
8 |
60632824, 60655103, 60655556 |
NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950 NM_001177881, NM_001177882, NM_027756, BC095950 |
71306 |
14 |
molecular_function nucleus nucleus nucleoplasm cytoplasm cytoplasm plasma membrane plasma membrane biological_process membrane integral component of membrane cell junction |
|
| TC1100003505.mm.2 |
Akap1 |
A kinase (PRKA) anchor protein 1 |
11 |
-88830791, -88830791, -88830791 |
NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310 |
11640 |
58 |
nucleic acid binding RNA binding protein binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum lipid droplet apoptotic process microtubule binding negative regulation of cardiac muscle hypertrophy regulation of protein kinase A signaling membrane integral component of membrane protein kinase binding protein phosphatase binding mitochondrial crista protein phosphatase 2B binding neuromuscular junction protein kinase A regulatory subunit binding negative regulation of protein dephosphorylation negative regulation of protein import into nucleus postsynaptic membrane beta-tubulin binding molecular adaptor activity antiviral innate immune response |
|
| MG-1-pos-10343025_st |
|
|
|
|
|
|
|
|
|
| TC0200000459.mm.2 |
Surf2 |
surfeit gene 2 |
2 |
26916407 |
NM_013678, BC096401 NM_013678, BC096401 |
20931 |
21 |
molecular_function nucleoplasm nucleolus plasma membrane biological_process nuclear speck |
|
| MG-1-neg-10340688_st |
|
|
|
|
|
|
|
|
|
| TC1300002617.mm.2 |
Ipo11 |
importin 11 |
13 |
-106794438 |
NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 |
76582 |
23 |
protein binding nucleus nuclear envelope nucleoplasm cytoplasm cytosol cytosol protein import into nucleus ribosomal protein import into nucleus intracellular protein transport protein transport small GTPase binding nuclear import signal receptor activity |
|
| TC0600001744.mm.2 |
Klhl42 |
kelch-like 42 |
6 |
147091074 |
NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 |
232539 |
16 |
protein polyubiquitination protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoskeleton cell cycle Cul3-RING ubiquitin ligase complex regulation of microtubule-based process regulation of microtubule-based process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division |
|
| TC1700000705.mm.2 |
Mdc1 |
mediator of DNA damage checkpoint 1 |
17 |
35841497 |
NM_001010833 |
240087 |
55 |
nucleus nucleoplasm chromosome focal adhesion DNA repair cellular response to DNA damage stimulus cell cycle protein C-terminus binding nuclear body identical protein binding FHA domain binding |
|
| TC0X00002631.mm.2 |
Pola1 |
polymerase (DNA directed), alpha 1 |
X |
-93304765 |
NM_008892, BC138047 NM_008892, BC138047 |
18968 |
36 |
nucleotide binding DNA synthesis involved in DNA repair chromatin nucleoside binding nucleic acid binding DNA binding chromatin binding chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity protein binding nucleus nucleus nuclear envelope nucleoplasm alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex nucleolus cytoplasm cytosol DNA replication DNA replication DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication initiation DNA strand elongation involved in DNA replication leading strand elongation leading strand elongation lagging strand elongation lagging strand elongation double-strand break repair via nonhomologous end joining nuclear matrix transferase activity nucleotidyltransferase activity purine nucleotide binding purine nucleotide binding pyrimidine nucleotide binding pyrimidine nucleotide binding protein kinase binding regulation of type I interferon production metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding DNA biosynthetic process mitotic DNA replication initiation |
00230 00240 01100 03030 |
| TC1600000176.mm.2 |
Nde1 |
nudE neurodevelopment protein 1 |
16 |
14163274 |
NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 |
67203 |
49 |
establishment of mitotic spindle orientation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore neuron migration protein binding chromosome cytoplasm centrosome centrosome centrosome microtubule organizing center spindle cytoskeleton kinesin complex microtubule microtubule nucleation microtubule nucleation cell cycle chromosome segregation mitotic centrosome separation multicellular organism development nervous system development neuroblast proliferation microtubule binding microtubule binding cell migration protein domain specific binding cerebral cortex development cerebral cortex development cell differentiation forebrain development microtubule organizing center organization spindle pole centrosome identical protein binding identical protein binding synapse vesicle transport along microtubule vesicle transport along microtubule centrosome duplication cell division establishment of chromosome localization establishment of chromosome localization centrosome localization regulation of microtubule motor activity |
|
| TC0200000055.mm.2 |
Nudt5 |
nudix (nucleoside diphosphate linked moiety X)-type motif 5 |
2 |
5845033 |
NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595 |
53893 |
28 |
magnesium ion binding RNA binding nucleus nucleus nucleobase-containing compound metabolic process chromatin remodeling nucleoside phosphate metabolic process ribonucleoside diphosphate catabolic process transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-diphosphatase activity ADP-sugar diphosphatase activity D-ribose catabolic process ribose phosphate metabolic process snoRNA binding identical protein binding protein homodimerization activity 8-oxo-dGDP phosphatase activity metal ion binding ADP-ribose diphosphatase activity ADP-ribose diphosphatase activity ATP generation from poly-ADP-D-ribose |
00230 |
| TC0100003866.mm.2 |
Serpinb2 |
serine (or cysteine) peptidase inhibitor, clade B, member 2 |
1 |
107511509, 107511422 |
NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817 NM_001174170, NM_011111, BC138815, BC138817 |
18788 |
55 |
serine-type endopeptidase inhibitor activity extracellular region extracellular space cytoplasm negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity wound healing negative regulation of apoptotic process |
05146 |
| TC1200001420.mm.2 |
Gen1 |
GEN1, Holliday junction 5' flap endonuclease |
12 |
-11238937 |
NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158 NM_177331, BC090653, BC138157, BC138158 |
209334 |
21 |
magnesium ion binding four-way junction DNA binding four-way junction DNA binding double-strand break repair via homologous recombination DNA binding catalytic activity nuclease activity endonuclease activity nucleus centrosome DNA repair cellular response to DNA damage stimulus crossover junction endodeoxyribonuclease activity regulation of centrosome duplication hydrolase activity 5'-flap endonuclease activity 5'-flap endonuclease activity replication fork processing protein homodimerization activity metal ion binding resolution of recombination intermediates resolution of mitotic recombination intermediates positive regulation of mitotic cell cycle spindle assembly checkpoint |
|
| TC0600003136.mm.2 |
Ncapd2 |
non-SMC condensin I complex, subunit D2 |
6 |
-125168006 |
NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133 |
68298 |
32 |
nuclear chromosome mitotic cell cycle condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation histone binding histone binding pronucleus cell division |
|
| MG-1-neg-10341224_st |
|
|
|
|
|
|
|
|
|
| MG-1-neg-10342714_st |
|
|
|
|
|
|
|
|
|
| MG-1-neg-10342165_st |
|
|
|
|
|
|
|
|
|
| TC0900001623.mm.2 |
Ss18l2 |
SS18, nBAF chromatin remodeling complex subunit like 2 |
9 |
121710388 |
NM_026794, BC027548 NM_026794, BC027548 |
26901 |
17 |
molecular_function transcription coactivator activity nucleus positive regulation of transcription by RNA polymerase II positive regulation of dendrite morphogenesis |
|
| TC1100002593.mm.2 |
Thg1l |
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
11 |
-45945305, -45945305 |
NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 |
66628 |
16 |
nucleotide binding magnesium ion binding guanyl-nucleotide exchange factor activity ATP binding GTP binding cytoplasm mitochondrion tRNA modification response to oxidative stress tRNA processing tRNA processing mitochondrial fusion tRNA guanylyltransferase activity tRNA guanylyltransferase activity transferase activity nucleotidyltransferase activity identical protein binding metal ion binding protein homotetramerization stress-induced mitochondrial fusion transferase complex |
|
| TC1300000273.mm.2 |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
13 |
24327403, 24415121 |
NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 |
12763 |
51 |
cytoplasm endoplasmic reticulum oxidoreductase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate metabolic process metal ion binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding |
00520 |
| TC0200001874.mm.2 |
Slc24a5 |
solute carrier family 24, member 5 |
2 |
125068126 |
NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643 NM_175034, BC094232, BC144866, BC145643 |
317750 |
17 |
calcium channel activity Golgi apparatus trans-Golgi network trans-Golgi network ion transport potassium ion transport sodium ion transport calcium ion transport cellular calcium ion homeostasis calcium, potassium:sodium antiporter activity calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral component of membrane melanocyte differentiation ion transmembrane transport regulation of melanin biosynthetic process negative regulation of melanin biosynthetic process response to stimulus transmembrane transport calcium ion transmembrane transport |
|
| TC0800002523.mm.2 |
Abce1 |
ATP-binding cassette, sub-family E (OABP), member 1 |
8 |
-79683441 |
NM_015751, BC005422 NM_015751, BC005422 |
24015 |
31 |
ribosomal subunit export from nucleus nucleotide binding iron ion binding ATP binding cytoplasm mitochondrion cytosol eukaryotic translation initiation factor 3 complex translational initiation translational termination ATPase activity ribosomal small subunit binding endoribonuclease inhibitor activity negative regulation of endoribonuclease activity |
|
| TC1300001922.mm.2 |
Kif13a |
kinesin family member 13A |
13 |
-46749087 |
NM_010617 |
16553 |
23 |
nucleotide binding microtubule motor activity microtubule motor activity protein binding ATP binding cytoplasm endosome Golgi apparatus centrosome cytoskeleton kinesin complex microtubule intracellular protein transport intracellular protein transport microtubule-based movement cell cycle microtubule binding endosome to lysosome transport endosome membrane protein transport membrane ATPase activity midbody melanosome organization regulation of cytokinesis trans-Golgi network membrane vesicle cargo loading Golgi to plasma membrane protein transport cell division plus-end-directed vesicle transport along microtubule |
|
| TC1300000715.mm.2 |
Rmi1 |
RecQ mediated genome instability 1 |
13 |
58402247, 58402596 |
NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694 NM_001168248, NM_028904, NR_031761, BC037694 |
74386 |
24 |
nucleotide binding resolution of meiotic recombination intermediates double-strand break repair via homologous recombination response to dietary excess reduction of food intake in response to dietary excess molecular_function nucleus nucleoplasm DNA replication response to glucose nuclear body nuclear body RecQ family helicase-topoisomerase III complex multicellular organism growth glucose homeostasis |
|
| TC1700000896.mm.2 |
Dnph1 |
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
17 |
46496788 |
NM_207161, BC048355 NM_207161, BC048355 |
381101 |
17 |
nucleus nucleus cytoplasm metabolic process nucleotide metabolic process deoxyribonucleoside monophosphate catabolic process deoxyribonucleoside monophosphate catabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds positive regulation of cell growth identical protein binding protein homodimerization activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity |
|
| TC0100001756.mm.2 |
Taf1a |
TATA-box binding protein associated factor, RNA polymerase I, A |
1 |
183388984, 183388884 |
NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 NM_001277957, NM_001277958, NM_001277959, NM_021466, BC061106, BC138425 |
21339 |
19 |
RNA polymerase I transcription regulator complex DNA binding protein binding nucleus nucleoplasm nucleoplasm transcription by RNA polymerase I microtubule cytoskeleton |
|
| TC0X00001084.mm.2 |
P2ry10b |
purinergic receptor P2Y, G-protein coupled 10B |
X |
107148926, 107149453, 107149614 |
NM_001122595, NM_001122596, NM_175442 NM_001122595, NM_001122596, NM_175442 NM_001122595, NM_001122596, NM_175442 |
213438 |
11 |
G protein-coupled receptor activity integral component of plasma membrane positive regulation of Rho protein signal transduction positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
|
| TC1500002075.mm.2 |
Abcd2 |
ATP-binding cassette, sub-family D (ALD), member 2 |
15 |
-91145870 |
NM_011994, BC019187 NM_011994, BC019187 |
26874 |
52 |
very long-chain fatty acid metabolic process nucleotide binding long-chain fatty acid transporter activity protein binding ATP binding mitochondrion peroxisome peroxisomal membrane peroxisomal membrane fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation peroxisome organization response to bacterium long-chain fatty acid import into peroxisome membrane integral component of membrane ATPase activity positive regulation of fatty acid beta-oxidation positive regulation of fatty acid beta-oxidation ATPase-coupled transmembrane transporter activity very long-chain fatty acid catabolic process very long-chain fatty acid catabolic process very long-chain fatty acid catabolic process protein homodimerization activity myelin maintenance transmembrane transport negative regulation of cytokine production involved in inflammatory response negative regulation of reactive oxygen species biosynthetic process neuron projection maintenance positive regulation of unsaturated fatty acid biosynthetic process |
02010 04146 |
| TC1100000383.mm.2 |
Pank3 |
pantothenate kinase 3 |
11 |
35769494 |
NM_145962, BC027089 NM_145962, BC027089 |
211347 |
27 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus cytoplasm cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity vitamin binding protein homodimerization activity acetyl-CoA binding |
00770 01100 |
| TC1300002380.mm.2 |
Rasa1 |
RAS p21 protein activator 1 |
13 |
-85214698 |
NM_145452, BC013637 NM_145452, BC013637 |
218397 |
91 |
ruffle phosphotyrosine residue binding positive regulation of protein phosphorylation negative regulation of cell-matrix adhesion GTPase activator activity signaling receptor binding platelet-derived growth factor receptor binding protein binding cytosol cytosol plasma membrane plasma membrane negative regulation of cell adhesion signal transduction transcription factor binding membrane kinase binding regulation of actin filament polymerization receptor tyrosine kinase binding nuclear membrane cellular response to platelet-derived growth factor stimulus response to drug negative regulation of apoptotic process protein kinase B binding positive regulation of GTPase activity ion channel binding protein-containing complex binding positive regulation of glucose import positive regulation of fibroblast proliferation blood vessel morphogenesis positive regulation of peptidyl-tyrosine phosphorylation GTPase binding cellular response to epidermal growth factor stimulus activation of GTPase activity protein tyrosine kinase binding |
04010 04360 |
| TC1300002119.mm.2 |
Golm1 |
golgi membrane protein 1 |
13 |
-59634995 |
NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486 NM_001035122, NM_027307, BC011152, BC098486 |
105348 |
24 |
molecular_function Golgi apparatus Golgi apparatus nucleus organization membrane integral component of membrane regulation of lipid metabolic process |
|